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51. Examining relationships between perceptions and objective assessments of neighborhood environment and sedentary time: Data from the Washington, D.C. Cardiovascular Health and Needs Assessment

Author

Ahuja, Chaarushi, Ayers, Colby, Hartz, Jacob, Adu-Brimpong, Joel, Thomas, Samantha, Mitchell, Valerie, Peters-Lawrence, Marlene, Sampson, Dana, Brooks, Alyssa T., Wallen, Gwenyth, Johnson, Allan, Graham, Lennox, Graham, Avis, Rivers, Joshua, Yingling, Leah, and Powell-Wiley, Tiffany M.

Published
2018
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52. Associations of Cumulative Perceived Stress with Cardiovascular Risk Factors and Outcomes: Findings from The Dallas Heart Study

Author

Eleazu, Ijeoma, primary, Ayers, Colby, additional, Navar, Ann Marie, additional, Salhadar, Karim, additional, Albert, Michele, additional, Carnethon, Mercedes, additional, Brown, Sherwood, additional, Nwobodo, Lucy Ogbu, additional, Carter, Spencer, additional, Bess, Courtney, additional, Powell-Wiley, Tiffany M., additional, and de Lemos, James A., additional

Published
2023
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54. Abstract 370: Corticosterone-mediated Associations Between Neighborhood Environment Perceptions and Lysosomal Acid Lipase Levels - Data From The Washington, D.C. Cardiovascular Health and Needs Assessment

Author

Baumer, Yvonne, primary, Ortiz-Whittingham, Lola, additional, Cintron, Manuel A, additional, Tarfa, Hannatu A, additional, Dave, Ayushi, additional, Saurabh, Abhinav, additional, Collins, Billy S, additional, Mitchell, Valerie, additional, and Powell-Wiley, Tiffany M, additional

Published
2023
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55. A community feasibility study of a cooking behavior intervention in African-American adults at risk for cardiovascular disease: DC COOKS (DC Community Organizing for Optimal culinary Knowledge Study) with Heart

Author

Farmer, Nicole, Powell-Wiley, Tiffany M., Middleton, Kimberly R., Roberson, Brenda, Flynn, Sharon, Brooks, Alyssa T., Kazmi, Narjis, Mitchell, Valerie, Collins, Billy, Hingst, Rachel, Swan, Lucy, Yang, Shanna, Kakar, Seema, Harlan, Timothy, and Wallen, Gwenyth R.

Published
2020
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58. Immune cell phenotyping in low blood volumes for assessment of cardiovascular disease risk, development, and progression: a pilot study

Author

Baumer, Yvonne, Gutierrez-Huerta, Cristhian A., Saxena, Ankit, Dagur, Pradeep K., Langerman, Steven D., Tamura, Kosuke, Ceasar, Joniqua N., Andrews, Marcus R., Mitchell, Valerie, Collins, Billy S., Yu, Quan, Teague, Heather L., Playford, Martin P., Bleck, Christopher K. E., Mehta, Nehal N., McCoy, J. Philip, and Powell-Wiley, Tiffany M.

Published
2020
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59. Association of neighborhood gentrification with prostate cancer and immune markers in African American and European American me.

Author

Pichardo, Catherine M., Ezeani, Adaora, Pichardo, Margaret S., Agurs-Collins, Tanya, Powell-Wiley, Tiffany M., Ryan, Brid, Minas, Tsion Zewdu, Bailey-Whyte, Maeve, Wei Tang, Dorsey, Tiffany H., Wooten, William, Loffredo, Christopher A., and Ambs, Stefan

Subjects
GENTRIFICATION, PROSTATE cancer, BIOMARKERS, TUMOR markers, AFRICAN Americans, DISEASE risk factors
Abstract

Background: Prior studies showed that neighborhood deprivation increases the risk of lethal prostate cancer. However, the role of neighborhood gentrification in prostate cancer development and outcome remains poorly understood. We examined the relationships of gentrification with prostate cancer and serum proteomedefined inflammation and immune function in a diverse cohort. Methods: The case–control study included 769 cases [405 African American (AA), 364 European American (EA) men] and 1023 controls (479 AA and 544 EA), with 219 all-cause and 59 prostate cancer-specific deaths among cases. Geocodes were linked to a neighborhood gentrification index (NGI) derived from US Census data. Cox and logistic regression, and MANOVA, were used to determine associations between NGI, as continuous or quintiles (Q), and outcomes. Results: Adjusting for individual socioeconomic status (SES), continuous NGI was positively associated with prostate cancer among all men (odds ratio [OR] 1.07, 95% confidence interval [CI] 1.01–1.14). AA and low-income men experienced the highest odds of prostate cancer when residing in tracts with moderate gentrification, whereas EA men experienced reduced odds of regional/metastatic cancer with increased gentrification in SES-adjusted analyses. Continuous NGI also associated with mortality among men presenting with localized disease and low-income men in SES-adjusted Cox regression analyses. NGI was not associated with serum proteome-defined chemotaxis, inflammation, and tumor immunity suppression. Conclusions: Findings show that neighborhood gentrification associates with prostate cancer and mortality in this diverse population albeit associations were heterogenous within subgroups. The observations suggest that changing neighborhood socioeconomic environments may affect prostate cancer risk and outcome, likely through multifactorial mechanisms. [ABSTRACT FROM AUTHOR]

Published
2024
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61. Associations of Cumulative Perceived Stress with Cardiovascular Risk Factors and Outcomes: Findings from The Dallas Heart Study

Author

Eleazu, Ijeoma, Ayers, Colby, Navar, Ann Marie, Salhadar, Karim, Albert, Michele, Carnethon, Mercedes, Brown, Sherwood, Nwobodo, Lucy Ogbu, Carter, Spencer, Bess, Courtney, Powell-Wiley, Tiffany M., and de Lemos, James A.

Subjects
Article
Abstract

BACKGROUND: Data remain sparse regarding the impact of chronic stress on cardiovascular disease (CVD) risk factors and outcomes. Prior work has been limited by incomplete assessments of perceived stress and focus on single stress domains. We evaluated the association between a composite measure of perceived stress and CVD risk factors and outcomes. METHODS: Participants from the Dallas Heart Study phase 2 (2007-2009) without prevalent CVD who completed questionnaire assessments of perceived stress were included (n=2685). Individual perceived stress subcomponents (generalized stress, psychosocial, financial, and neighborhood stress) were standardized and integrated into a single cumulative stress score (CSS) with equal weighting for each component. Associations between CSS and demographics, psychosocial variables and cardiac risk factors were assessed in univariable and multivariable analyses. Cox proportional hazards models were used to determine associations of the CSS with atherosclerotic CVD (ASCVD) and Global CVD (ASCVD, heart failure, and atrial fibrillation) after adjustment for demographics and traditional risk factors. RESULTS: Median age of the study population was 48 years, 55% were female, 49% Black and 15% Hispanic/Latinx. CSS was higher among participants who were younger, female, Black or Hispanic, and those with lower income and educational attainment (p one year previously (p

Published
2023

68. New insights in the mechanisms of weight-loss maintenance:Summary from a Pennington symposium

Author

Flanagan, Emily W., Spann, Redin, Berry, Sarah E., Berthoud, Hans Rudolf, Broyles, Stephanie, Foster, Gary D., Krakoff, Jonathan, Loos, Ruth J.F., Lowe, Michael R., Ostendorf, Danielle M., Powell-Wiley, Tiffany M., Redman, Leanne M., Rosenbaum, Michael, Schauer, Philip R., Seeley, Randy J., Swinburn, Boyd A., Hall, Kevin, Ravussin, Eric, Flanagan, Emily W., Spann, Redin, Berry, Sarah E., Berthoud, Hans Rudolf, Broyles, Stephanie, Foster, Gary D., Krakoff, Jonathan, Loos, Ruth J.F., Lowe, Michael R., Ostendorf, Danielle M., Powell-Wiley, Tiffany M., Redman, Leanne M., Rosenbaum, Michael, Schauer, Philip R., Seeley, Randy J., Swinburn, Boyd A., Hall, Kevin, and Ravussin, Eric

Abstract

Obesity is a chronic disease that affects more than 650 million adults worldwide. Obesity not only is a significant health concern on its own, but predisposes to cardiometabolic comorbidities, including coronary heart disease, dyslipidemia, hypertension, type 2 diabetes, and some cancers. Lifestyle interventions effectively promote weight loss of 5% to 10%, and pharmacological and surgical interventions even more, with some novel approved drugs inducing up to an average of 25% weight loss. Yet, maintaining weight loss over the long-term remains extremely challenging, and subsequent weight gain is typical. The mechanisms underlying weight regain remain to be fully elucidated. The purpose of this Pennington Biomedical Scientific Symposium was to review and highlight the complex interplay between the physiological, behavioral, and environmental systems controlling energy intake and expenditure. Each of these contributions were further discussed in the context of weight-loss maintenance, and systems-level viewpoints were highlighted to interpret gaps in current approaches. The invited speakers built upon the science of obesity and weight loss to collectively propose future research directions that will aid in revealing the complicated mechanisms involved in the weight-reduced state.

Published
2023

70. Comparing Methods to Identify Wear-Time Intervals for Physical Activity With the Fitbit Charge 2.

Author

Claudel, Sophie E., Tamura, Kosuke, Troendle, James, Andrews, Marcus R., Ceasar, Joniqua N., Mitchell, Valerie M., Vijayakumar, Nithya, and Powell-Wiley, Tiffany M.

Subjects
PHYSICAL fitness mobile apps, BLACK people, WEARABLE technology, PHYSICAL activity, HEART beat, DESCRIPTIVE statistics, STATISTICAL sampling, ALGORITHMS
Abstract

There is no established method for processing data from commercially available physical activity trackers. This study aims to develop a standardized approach to defining valid wear time for use in future interventions and analyses. Sixteen African American women (mean age = 62.1 years and mean body mass index = 35.5 kg/m2) wore the Fitbit Charge 2 for 20 days. Method 1 defined a valid day as ≥10-hr wear time with heart rate data. Method 2 removed minutes without heart rate data, minutes with heart rate ≤ mean − 2 SDs below mean and ≤2 steps, and nighttime. Linear regression modeled steps per day per week change. Using Method 1 (n = 292 person-days), participants had 20.5 (SD = 4.3) hr wear time per day compared with 16.3 (SD = 2.2) hr using Method 2 (n = 282) (p <.0001). With Method 1, participants took 7,436 (SD = 3,543) steps per day compared with 7,298 (SD = 3,501) steps per day with Method 2 (p =.64). The proposed algorithm represents a novel approach to standardizing data generated by physical activity trackers. Future studies are needed to improve the accuracy of physical activity data sets. [ABSTRACT FROM AUTHOR]

Published
2021
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74. Association of Rurality With Risk of Heart Failure

Author

Turecamo, Sarah E., primary, Xu, Meng, additional, Dixon, Debra, additional, Powell-Wiley, Tiffany M., additional, Mumma, Michael T., additional, Joo, Jungnam, additional, Gupta, Deepak K., additional, Lipworth, Loren, additional, and Roger, Véronique L., additional

Published
2023
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76. Use of a focus group-based cognitive interview methodology to validate a cooking behavior survey among African-American adults

Author

Farmer, Nicole, primary, Powell-Wiley, Tiffany M., additional, Middleton, Kimberly R., additional, Brooks, Alyssa T., additional, Mitchell, Valerie, additional, Troncoso, Melissa, additional, Ceasar, Joniqua, additional, Claudel, Sophie E., additional, Andrews, Marcus R., additional, Kazmi, Narjis, additional, Johnson, Allan, additional, and Wallen, Gwenyth R., additional

Published
2022
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79. Customizing Place-Tailored Messaging Using a Multilevel Approach: Pilot Study of the Step It Up Physical Activity Mobile App Tailored to Neighborhood Environment

Author

Vijayakumar, Nithya P., primary, Neally, Sam J., additional, Potharaju, Kameswari A., additional, Curlin, Kaveri, additional, Troendle, James F., additional, Collins, Billy S., additional, Mitchell, Valerie M., additional, Tamura, Kosuke, additional, Ayers, Colby, additional, Pita, Mario A., additional, Tarfa, Hannatu A., additional, Thompson, Keitra, additional, Osei Baah, Foster, additional, Baez, Andrew S., additional, Ortiz-Whittingham, Lola R., additional, Wills Gallagher, Jennifer, additional, McCoy, Regina, additional, Heist, Michael, additional, Gutierrez-Huerta, Cristhian A., additional, Turner, Briana S., additional, Baumer, Yvonne, additional, Farmer, Nicole, additional, Wallen, Gwenyth R., additional, Dodge, Tonya, additional, and Powell-Wiley, Tiffany M., additional

Published
2022
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81. Digital Food Records in Community-Based Interventions: Mixed-Methods Pilot Study

Author

Fowler, Lauren A, Yingling, Leah R, Brooks, Alyssa T, Wallen, Gwenyth R, Peters-Lawrence, Marlene, McClurkin, Michael, Wiley Jr, Kenneth L, Mitchell, Valerie M, Johnson, Twanda D, Curry, Kendrick E, Johnson, Allan A, Graham, Avis P, Graham, Lennox A, and Powell-Wiley, Tiffany M

Subjects
Information technology, T58.5-58.64, Public aspects of medicine, RA1-1270
Abstract

BackgroundA pressing need exists to understand and optimize the use of dietary assessment tools that can be used in community-based participatory research (CBPR) interventions. A digital food record, which uses a mobile device to capture the dietary intake through text and photography inputs, is a particularly promising mobile assessment method. However, little is understood about the acceptability and feasibility of digital food records in CBPR and how to best tailor dietary assessment tools to the needs of a community. ObjectiveThe objective of our study was to evaluate the acceptability and feasibility of digital food records among church-based populations in resource-limited wards of Washington, DC, USA, using a mixed-methods approach. MethodsThis community-based pilot study was conducted as part of the Washington, DC Cardiovascular Health and Needs Assessment. Participants (n=17) received a mobile device (iPod Touch) to photodocument their dietary intake for a 3-day digital food record using a mobile app, FitNinja (Vibrent Health). The acceptability of the digital food record was explored through the thematic analysis of verbatim transcripts from a moderated focus group (n=8). In addition, the feasibility was evaluated by the percentage of participants complying with instructions (ie, capturing both before and after meal photos for at least 2 meals/day for 3 days). ResultsQualitative themes identified were related to (1) the feasibility and acceptability of the mobile device and app, including issues in recording the dietary information and difficulty with photodocumentation; (2) suggestions for additional support and training experiences; and (3) comparisons with other mobile apps. Overall, the participants accepted the digital food record by demonstrating satisfaction with the tool and intent to continue the use (eg, participants recorded an average of 5.2, SD 7, consecutive days). Furthermore, of the 17 participants, 15 photodocumented at least 1 meal during the study period and 3 fully complied with the digital food record instructions. ConclusionsThis study demonstrated digital food records as an acceptable tool in CBPR and identified contributors and barriers to the feasibility of digital food records for future research. Engaging community members in the implementation of novel assessment methods allows for the tailoring of technology to the needs of the community and optimizing community-based interventions. Trial RegistrationClinicalTrials.gov NCT01927783; https://www.clinicaltrials.gov/ct2/show/NCT01927783 (Archived by WebCite at http://www.webcitation.org/70WzaFWb6)

Published
2018
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83. The Impact of a Place-Tailored Digital Health App Promoting Exercise Classes on African American Women’s Physical Activity and Obesity: Simulation Study

Author

Powell-Wiley, Tiffany M, primary, Martinez, Marie F, additional, Tamura, Kosuke, additional, Neally, Sam J, additional, O'Shea, Kelly J, additional, Curlin, Kaveri, additional, Albarracin, Yardley, additional, Vijayakumar, Nithya P, additional, Morgan, Matthew, additional, Ortiz-Chaparro, Erika, additional, Bartsch, Sarah M, additional, Osei Baah, Foster, additional, Wedlock, Patrick T, additional, Ortiz-Whittingham, Lola R, additional, Scannell, Sheryl, additional, Potharaju, Kameswari A, additional, Randall, Samuel, additional, Solano Gonzales, Mario, additional, Domino, Molly, additional, Ranganath, Kushi, additional, Hertenstein, Daniel, additional, Syed, Rafay, additional, Weatherwax, Colleen, additional, and Lee, Bruce Y, additional

Published
2022
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84. Machine Learning–Based Models Incorporating Social Determinants of Health vs Traditional Models for Predicting In-Hospital Mortality in Patients With Heart Failure

Author

Segar, Matthew W., primary, Hall, Jennifer L., additional, Jhund, Pardeep S., additional, Powell-Wiley, Tiffany M., additional, Morris, Alanna A., additional, Kao, David, additional, Fonarow, Gregg C., additional, Hernandez, Rosalba, additional, Ibrahim, Nasrien E., additional, Rutan, Christine, additional, Navar, Ann Marie, additional, Stevens, Laura M., additional, and Pandey, Ambarish, additional

Published
2022
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90. Dopamine D2‐Like Receptor Signaling and Downregulation of Filamin‐A May Drive the Association Between Neighborhood Socioeconomic Status and CCR2 Expression on Monocytes

Author

Pita, Mario A., primary, Baumer, Yvonne, additional, Turner, Briana S., additional, Gutierrez‐Huerta, Cristhian A., additional, Neally, Sam J., additional, Baez, Andrew S., additional, Farmer, Nicole, additional, Mitchell, Valerie M., additional, Collins, Billy S., additional, and Powell‐Wiley, Tiffany M., additional

Published
2022
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95. Cardiometabolic Health Outcomes Associated With Discordant Visceral and Liver Fat Phenotypes: Insights From the Dallas Heart Study and UK Biobank

Author

Tejani, Sanaa, McCoy, Cody, Ayers, Colby R., Powell-Wiley, Tiffany M., Després, Jean-Pierre, Linge, Jennifer, Dahlqvist Leinhard, Olof, Petersson, Mikael, Borga, Magnus, Neeland, Ian J., Tejani, Sanaa, McCoy, Cody, Ayers, Colby R., Powell-Wiley, Tiffany M., Després, Jean-Pierre, Linge, Jennifer, Dahlqvist Leinhard, Olof, Petersson, Mikael, Borga, Magnus, and Neeland, Ian J.

Abstract

Objective: To evaluate the cardiometabolic outcomes associated with discordant visceral adipose tissue (VAT) and liver fat (LF) phenotypes in 2 cohorts. Patients and Methods: Participants in the Dallas Heart Study underwent baseline imaging from January 1, 2000, through December 31, 2002, and were followed for incident cardiovascular disease (CVD) and type 2 diabetes mellitus (T2DM) through 2013. Associations between VAT-LF groups (low-low, high-low, low-high, and high-high) and outcomes were assessed using multivariable- adjusted regression and were replicated in the independent UK Biobank. Results: The Dallas Heart Study included 2064 participants (mean SD age, 449 years; 54% female; 47% black). High VATehigh LF and high VATelow LF were associated with prevalent atheroscle- rosis, whereas low VATehigh LF was not. Of 1731 participants without CVD/T2DM, 128 (7.4%) developed CVD and 95 (5.5%) T2DM over a median of 12 years. High VATehigh LF and high VATelow LF were associated with increased risk of CVD (hazard ratios [HRs], 2.0 [95% CI, 1.3 to 3.2] and 2.4 [95% CI, 1.4 to 4.1], respectively) and T2DM (odds ratios [ORs], 7.8 [95% CI, 3.8 to 15.8] and 3.3 [95% CI, 1.4 to 7.8], respectively), whereas low VATehigh LF was associated with T2DM (OR, 2.7 [95% CI, 1.1 to 6.7]). In the UK Biobank (N1⁄422,354; April 2014-May 2020), only high VATelow LF remained associated with CVD after multivariable adjustment for age and body mass index (HR, 1.5 [95% CI, 1.2 to 1.9]). Conclusion: Although VAT and LF are each associated with cardiometabolic risk, these observations demonstrate the importance of separating their cardiometabolic implications when there is presence or absence of either or both in an individual., Funding: National Institute of Diabetes and Digestive and Kidney Diseases [K23 DK106520]; National Center for Advancing Translational Sciences [UL1TR001105]; Swedish Research Council [VR-2019-04751]

Published
2022
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98. Use of an Implementation Research Framework in Community-Engaged Dietary Intervention

Author

Farmer, Nicole, Wildridge, Stephanie, Tuason, Ralph, Metellus, Rebecca, Wells, Ayanna, Powell-Wiley, Tiffany M., and Wallen, Gwenyth R.

Abstract

African-Americans have an increased risk for diet-related diseases. Cooking is a dietary behavior that increases self-efficacy and social support, factors shown to be efficacious in optimizing diet. However, the overall inclusion of African-Americans within dietary interventions remains a key gap area for addressing diet-related disparities. The use of implementation frameworks, such as RE-AIM (Reach, Effectiveness, Adoption, Implementation, and Maintenance) for planning interventions may assist in improving inclusion of African-American predominate communities in dietary interventions.

Published
2024
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