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982 results on '"Pin, Isabelle"'

51. Prevalence of asthma-like symptoms with ageing

Author

Jarvis, Debbie, Newson, Roger, Janson, Christer, Corsico, Angelo, Heinrich, Joachim, Anto, Josep M, Abramson, Michael J, Kirsten, Anne-Marie, Zock, Jan Paul, Bono, Roberto, Demoly, Pascal, Leynaert, Bénédicte, Raherison, Chantal, Pin, Isabelle, Gislason, Thorarinn, Jogi, Rain, Schlunssen, Vivi, Svanes, Cecilie, Watkins, John, Weyler, Joost, Pereira-Vega, Antonio, Urrutia, Isabel, Gullón, Jose A, Forsberg, Bertil, Probst-Hensch, Nicole, Boezen, H Marike, Martinez-Moratalla Rovira, Jesús, Accordini, Simone, de Marco, Roberto, and Burney, Peter

Published
2018
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52. Early-life exposure to a mixture of phthalates and phenols and child social behavior in a new type of mother-child cohort relying on within-subject pools of repeated urine biospecimens

Author

Mustieles, Vicente, primary, Rolland, Matthieu, additional, Pin, Isabelle, additional, Thomsen, Cathrine, additional, Sakhi, Amrit, additional, Sabaredzovic, Azemira, additional, Guichardet, Karine, additional, Slama, Rémy, additional, Philippat, Claire, additional, and Study Group, SEPAGES, additional

Published
2022
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54. Prenatal exposure to triclosan assessed through repeated urine samples and placental DNA methylation in the SEPAGES cohort

Author

Jedynak, Paulina, primary, Broséus, Lucile, additional, Tost, Jörg, additional, Busato, Florence, additional, Gabet, Stephan, additional, Thomsen, Cathrine, additional, Sakhi, Amrit K., additional, Pin, Isabelle, additional, Slama, Rémy, additional, Lepeule, Johanna, additional, Philippat, Claire, additional, and Study group, SEPAGES, additional

Published
2022
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58. Early delivery following chronic and acute ambient temperature exposure: a comprehensive survival approach.

Author

Hough, Ian, Rolland, Matthieu, Guilbert, Ariane, Seyve, Emie, Heude, Barbara, Slama, Rémy, Lyon-Caen, Sarah, Pin, Isabelle, Chevrier, Cécile, Kloog, Itai, and Lepeule, Johanna

Subjects
PREMATURE labor, WEATHER hazards, TEMPERATE climate, TEMPERATURE, HEALTH policy, HEAT waves (Meteorology)
Abstract

Background Ambient temperature, particularly heat, is increasingly acknowledged as a trigger for preterm delivery but study designs have been limited and results mixed. We aimed to comprehensively evaluate the association between ambient temperature throughout pregnancy and preterm delivery. Methods We estimated daily temperature throughout pregnancy using a cutting-edge spatiotemporal model for 5347 live singleton births from three prospective cohorts in France, 2002–2018. We performed Cox regression (survival analysis) with distributed lags to evaluate time-varying associations with preterm birth simultaneously controlling for exposure during the first 26 weeks and last 30 days of pregnancy. We examined weekly mean, daytime, night-time and variability of temperature, and heatwaves accounting for adaptation to location and season. Results Preterm birth risk was higher following cold (5th vs 50th percentile of mean temperature) 7–9 weeks after conception [relative risk (RR): 1.3, 95% CI: 1.0–1.6 for 2°C vs 11.6°C] and 10–4 days before delivery (RR: 1.6, 95% CI: 1.1–2.1 for 1.2°C vs 12.1°C). Night-time heat (95th vs 50th percentile of minimum temperature; 15.7°C vs 7.4°C) increased risk when exposure occurred within 5 weeks of conception (RR: 2.0, 95% CI: 1.05–3.8) or 20–26 weeks after conception (RR: 2.9, 95% CI: 1.2–6.8). Overall and daytime heat (high mean and maximum temperature) showed consistent effects. We found no clear associations with temperature variability or heatwave indicators, suggesting they may be less relevant for preterm birth. Conclusions In a temperate climate, night-time heat and chronic and acute cold exposures were associated with increased risk of preterm birth. These results suggest night-time heat as a relevant indicator. In the context of rising temperatures and more frequent weather hazards, these results should inform public health policies to reduce the growing burden of preterm births. [ABSTRACT FROM AUTHOR]

Published
2023
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63. Female sex hormones and symptoms of obstructive sleep apnea in European women of a population-based cohort

Author

Sigurðardóttir, Erla S., primary, Gislason, Thorarinn, additional, Benediktsdottir, Bryndis, additional, Hustad, Steinar, additional, Dadvand, Payam, additional, Demoly, Pascal, additional, Franklin, Karl A., additional, Heinrich, Joachim, additional, Holm, Mathias, additional, van der Plaat, Diana A., additional, Jõgi, Rain, additional, Leynaert, Benedicte, additional, Lindberg, Eva, additional, Martinez-Moratalla, Jesus, additional, Sainz De Aja, Leire, additional, Pesce, Giancarlo, additional, Pin, Isabelle, additional, Raherison, Chantal, additional, Pereira-Vega, Antonio, additional, Real, Francisco Gómez, additional, and Triebner, Kai, additional

Published
2022
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65. Functional variation in allelic methylomes underscores a strong genetic contribution and reveals novel epigenetic alterations in the human epigenome

Author

Cheung, Warren A., Shao, Xiaojian, Morin, Andréanne, Siroux, Valérie, Kwan, Tony, Ge, Bing, Aïssi, Dylan, Chen, Lu, Vasquez, Louella, Allum, Fiona, Guénard, Frédéric, Bouzigon, Emmanuelle, Simon, Marie-Michelle, Boulier, Elodie, Redensek, Adriana, Watt, Stephen, Datta, Avik, Clarke, Laura, Flicek, Paul, Mead, Daniel, Paul, Dirk S., Beck, Stephan, Bourque, Guillaume, Lathrop, Mark, Tchernof, André, Vohl, Marie-Claude, Demenais, Florence, Pin, Isabelle, Downes, Kate, Stunnenberg, Hendrick G., Soranzo, Nicole, Pastinen, Tomi, and Grundberg, Elin

Published
2017
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67. Associations between a mixture of phenols and phthalates and child behaviour in a French mother–child cohort with repeated assessment of exposure

Author

Guilbert, Ariane, Rolland, Matthieu, Pin, Isabelle, Thomsen, Cathrine, Sakhi, Amrit, Sabaredzovic, Azemira, Slama, Rémy, Guichardet, Karine, Philippat, Claire, Institute for Advanced Biosciences / Institut pour l'Avancée des Biosciences (Grenoble) (IAB), Etablissement français du sang - Auvergne-Rhône-Alpes (EFS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre Hospitalier Universitaire [Grenoble] (CHU)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA), Université Grenoble Alpes (UGA), Norwegian Institute of Public Health [Oslo] (NIPH), ANR-19-CE36-0003,EDeN,Exposition précoces aux perturbateurs endocriniens et neurodéveloppement de l'enfant : le rôle de l'axe hypothalamo-hypophysaire(2019), ANR-12-PDOC-0029,ANR-12-PDOC-0029-01,ANR-12-PDOC-0029-01, ANR-14-CE21-0007,SHALCOH,Expositions prénatales aux phénols et santé de l'enfant : analyse longitudinale(2014), ANR-18-CE36-0005,ETAPE,Exposition prénatale au tabac et à la pollution atmosphérique et effets sur la santé respiratoire et le neurodévelopment de l'enfant: rôle de la méthylation placentaire(2018), ANR-15-IDEX-0002,UGA,IDEX UGA(2015), ANR-15-IDEX-0005,ANR-15-IDEX5 ,ANR-15-IDEX5, European Project: 311765,EC:FP7:ERC,ERC-2012-StG_20111109,E-DOHAD(2013), Centre Hospitalier Universitaire [Grenoble] (CHU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Etablissement français du sang - Auvergne-Rhône-Alpes (EFS)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA), ANR-15-IDEX5ANR-15-IDEX5ANR-15-IDEX-0005, ANR-12-PDOC-0029,PAPER,Grossesse, pollution atmospherique, epigenetique, et sante respiratoire(2012), BARBAGALLO, Maïlys, Exposition précoces aux perturbateurs endocriniens et neurodéveloppement de l'enfant : le rôle de l'axe hypothalamo-hypophysaire - - EDeN2019 - ANR-19-CE36-0003 - AAPG2019 - VALID, Retour Post-Doctorant - Grossesse, pollution atmospherique, epigenetique, et sante respiratoire - - PAPER2012 - ANR-12-PDOC-0029 - PDOC - VALID, Appel à projets générique - Expositions prénatales aux phénols et santé de l'enfant : analyse longitudinale - - SHALCOH2014 - ANR-14-CE21-0007 - Appel à projets générique - VALID, APPEL À PROJETS GÉNÉRIQUE 2018 - Exposition prénatale au tabac et à la pollution atmosphérique et effets sur la santé respiratoire et le neurodévelopment de l'enfant: rôle de la méthylation placentaire - - ETAPE2018 - ANR-18-CE36-0005 - AAPG2018 - VALID, IDEX UGA - - UGA2015 - ANR-15-IDEX-0002 - IDEX - VALID, and Environmentally-induced Developmental Origins of Health and Disease - E-DOHAD - - EC:FP7:ERC2013-02-01 - 2018-01-31 - 311765 - VALID

Subjects
Male, Weighted quantile sum regression, Child behavior, [SDV]Life Sciences [q-bio], Phthalic Acids, [SCCO] Cognitive science, Environmental Exposure, Bisphenols, Mother-Child Relations, Triclosan, [SDV] Life Sciences [q-bio], Environmental sciences, [SCCO]Cognitive science, Phenols, Phthalates, [SDV.SPEE] Life Sciences [q-bio]/Santé publique et épidémiologie, Pregnancy, Prenatal exposure, Humans, Environmental Pollutants, Female, GE1-350, [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie, Child
Abstract

International audience; Background: Synthetic phenols and phthalates can interfere with biological pathways involved in brain development. Despite the high within-subject temporal variability of urinary concentrations observed for their metabolites, studies investigating effects of phenols and phthalates on child behaviour often relied on a limited number of spot biospecimens to assess exposure. Besides, the majority did not consider mixture effects.Objectives: To study the combined effect of prenatal exposure to synthetic phenols and phthalates on child behaviour using repeated exposure measurements.Methods: We assessed concentrations of 12 phenols, 13 phthalate and 2 non-phthalate plasticizer metabolites in within-subject pools of multiple urine samples (median = 21 samples per individual pool) collected at two distinct time points during pregnancy in 416 mother-child pairs from the French SEPAGES cohort. Child behaviour was evaluated at two years using the Child Behaviour Checklist 1.5-5 (CBCL). Associations between a mixture of biomarkers of exposure and externalizing and internalizing behaviour scores were studied using adjusted Weighted Quantile Sum (WQS) regressions with a repeated holdout validation (100 repetitions).Results: The positive WQS indexes were associated with both the externalizing and internalizing behaviour scores in the whole population, indicating greater risk of behavioural problems. Stratification for child sex suggested stronger associations in girls than boys. On average, girls externalizing and internalizing scores increased by 3.67 points (95% CI: 1.24, 6.10) and 2.47 points (95 %CI: 0.60, 4.33) respectively, for an increase of one tertile in the WQS index, compared with 1.70 points (95 %CI: -0.42, 3.81) and 1.17 points (95 %CI: -0.50, 2.84) in boys. Main contributors for the associations observed in girls were bisphenol A (weight of 18%), triclosan (17%) and monoethyl phthalate (MEP, 15%) for the externalizing score and MEP (19%), mono-benzyl phthalate (MBzP, 19%) and mono-n-butyl phthalate (MnBP, 16%) for the internalizing score.Discussion: Our results suggest adverse associations between in utero exposure to a mixture of phenols and phthalates and child behaviour, mainly in girls. Public health consequences may be substantial due to the widespread exposure of the population to these compounds.

Published
2021
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68. Prenatal Exposure to PM2.5 Oxidative Potential and Lung Function in Infants and Preschool- Age Children: A Prospective Study.

Author

Marsal, Anouk, Slama, Rémy, Lyon-Caen, Sarah, S. Borlaza, Lucille Joanna, Jaffrezo, Jean-Luc, Boudier, Anne, Darfeuil, Sophie, Elazzouzi, Rhabira, Gioria, Yoann, Lepeule, Johanna, Chartier, Ryan, Pin, Isabelle, Quentin, Joane, Bayat, Sam, Uzu, Gaëlle, Siroux, Valérie, and the SEPAGES cohort study group

Subjects
LUNG physiology, PARTICULATE matter, MATERNAL exposure, STATISTICS, CONFIDENCE intervals, MULTIPLE regression analysis, PRENATAL exposure delayed effects, PULMONARY function tests, DESCRIPTIVE statistics, RESEARCH funding, BIOLOGICAL assay, BREATH tests, DATA analysis software, OXIDATION-reduction reaction, LONGITUDINAL method, PREGNANCY
Abstract

BACKGROUND: Fine particulate matter (PM2.5) has been found to be detrimental to respiratory health of children, but few studies have examined the effects of prenatal PM2.5 oxidative potential (OP) on lung function in infants and preschool children. OBJECTIVES: We estimated the associations of personal exposure to PM2.5  and OP during pregnancy on offspring objective lung function parameters and compared the strengths of associations between both exposure metrics. METHODS: We used data from 356 mother–child pairs from the SEPAGES cohort. PM filters collected twice during a week were analyzed for OP, using the dithiothreitol (DTT) and the ascorbic acid (AA) assays, quantifying the exposure of each pregnant woman. Lung function was assessed with tidal breathing analysis (TBFVL) and nitrogen multiple-breath washout (N2MBW) test, performed at 6 wk, and airwave oscillometry (AOS) performed at 3 y. Associations of prenatal PM2.5  mass and OP with lung function parameters were estimated using multiple linear regressions. RESULTS: In neonates, an interquartile (IQR) increase in OPDTTv (0.89nmol/min/m³) was associated with a decrease in functional residual capacity (FRC) measured by N2MBW  [β = -2.26 mL ; 95% confidence interval (CI): -4.68, 0.15]. Associations with PM2.5  showed similar patterns in comparison with OPDTTv  but of smaller magnitude. Lung clearance index (LCI) and TBFVL parameters did not show any clear association with the exposures considered. At 3 y, increased frequency-dependent resistance of the lungs (Rrs7-19) from AOS tended to be associated with higher OPDTTv  (β = 0.09hPa×s/L ; 95% CI: -0.06, 0.24) and OPAAv  (IQR = 1.14nmol/min/m³ ; β = 0.12hPa×s/L ; 95% CI: -0.04, 0.27) but not with PM2.5  (IQR = 6.9µg/m³ ; β = 0.02hPa×s/L ; 95% CI: -0.13, 0.16). Results for FRC and Rrs7-19 remained similar in OP models adjusted on PM2.5. DISCUSSION: Prenatal exposure to OPDTTv was associated with several offspring lung function parameters over time, all related to lung volumes. [ABSTRACT FROM AUTHOR]

Published
2023
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69. Vaccination for Respiratory Infections in Patients with Heart Failure

Author

Fauroux, Brigitte, Khirani, Sonia, Amaddeo, Alessandro, MASSENAVETTE, Bruno, Bierme, Priscille, Taytard, Jessica, Stremler, Nathalie, Baravalle-Einaudi, Melisande, Mazenq, Julie, Ioan, Iulia, Schweitzer, Cyril, Lampin, Marie Emilie, Binoche, Alexandra, Mordacq, Clemence, Bergounioux, Jean, Mbieleu, Blaise, Rubinsztajn, Robert, Sigur, Elodie, Labouret, Geraldine, Genevois, Aline, Becourt, Arnaud, Hullo, Eglantine, Pin, Isabelle, Debelleix, Stéphane, Galodé, François, Bui, Stéphanie, Moreau, Johan, Renoux, Marie Catherine, Matecki, Stefan, Lavadera, Marc Lubrano, Heyman, Rachel, Pomedio, Michael, Le Clainche, Laurence, Bokov, Plamen, Masson, Alexandra, Hangard, Pauline, Menetrey, Celine, Jokic, Mikael, Gachelin, Elsa, Perisson, Caroline, Pervillé, Anne, Fina, Agnes, Giovannini-Chami, Lisa, Fleurence, Emmanuelle, Barzic, Audrey, Breining, Audrey, Ollivier, Morgane, Labbé, Guillaume, Coutier, Laurianne, Aubertin, Guillaume, Girerd, Nicolas, Chapet, Nicolas, Roubille, Camille, Roncalli, Jérôme, Salvat, Muriel, Mouquet, Frédéric, Lamblin, Nicolas, Gueffet, Jean-Pierre, Damy, Thibaud, Galinier, Michel, Tartiere, Jean-Michel, Janssen, Cécile, Berthelot, Emmanuelle, Aguilhon, Sylvain, Escamilla, Roger, Roubille, François, Institut Lorrain du Coeur et des Vaisseaux Louis Mathieu [Nancy], Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier), Physiologie & médecine expérimentale du Cœur et des Muscles [U 1046] (PhyMedExp), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), CHU Toulouse [Toulouse], Centre Hospitalier Universitaire [Grenoble] (CHU), Hôpital Privé Le Bois Ramsay Santé [Lille], Facteurs de Risque et Déterminants Moléculaires des Maladies liées au Vieillissement - U 1167 (RID-AGE), Institut Pasteur de Lille, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), Hôpital privé du Confluent [Nantes], Institut Mondor de Recherche Biomédicale (IMRB), Institut National de la Santé et de la Recherche Médicale (INSERM)-IFR10-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12), Hôpital Henri Mondor, Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées, Centre Hospitalier Intercommunal Toulon-La Seyne sur Mer - Hôpital Sainte-Musse, Centre Hospitalier Annecy-Genevois [Saint-Julien-en-Genevois], AP-HP Hôpital Bicêtre (Le Kremlin-Bicêtre), Université Paris-Sud - Paris 11 (UP11), Hôpital de Rangueil, Hôpital Privé Le Bois Ramsay Santé, Fédération des services de cardiologie [Rangueil], CHU Toulouse [Toulouse]-CHU Toulouse [Toulouse], CHITS, CHU Montpellier, Hôpital Larrey [Toulouse], Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12)-IFR10, Université de Montpellier (UM)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Centre Hospitalier Universitaire de Toulouse (CHU Toulouse), Université de Toulouse (UT), and MORNET, Dominique

Subjects
medicine.medical_specialty, pneumococcal vaccine, Influenza vaccine, [SDV]Life Sciences [q-bio], heart failure, review article, Disease, Review, 030204 cardiovascular system & hematology, medicine.disease_cause, law.invention, 03 medical and health sciences, respiratory infections, 0302 clinical medicine, Randomized controlled trial, law, Streptococcus pneumoniae, Medicine, 030212 general & internal medicine, Intensive care medicine, vaccination coverage, business.industry, General Medicine, medicine.disease, 3. Good health, Review article, [SDV] Life Sciences [q-bio], Vaccination, Pneumococcal vaccine, Heart failure, influenza vaccine, business, COVID-19 vaccine
Abstract

International audience; Bronchopulmonary infections are a major trigger of cardiac decompensation and are frequently associated with hospitalizations in patients with heart failure (HF). Adverse cardiac effects associated with respiratory infections, more specifically Streptococcus pneumoniae and influenza infections, are the consequence of inflammatory processes and thrombotic events. For both influenza and pneumococcal vaccinations, large multicenter randomized clinical trials are needed to evaluate their efficacy in preventing cardiovascular events, especially in HF patients. No study to date has evaluated the protective effect of the COVID-19 vaccine in patients with HF. Different guidelines recommend annual influenza vaccination for patients with established cardiovascular disease and also recommend pneumococcal vaccination in patients with HF. The Heart Failure group of the French Society of Cardiology recently strongly recommended vaccination against COVID-19 in HF patients. Nevertheless, the implementation of vaccination recommendations against respiratory infections in HF patients remains suboptimal. This suggests that a national health policy is needed to improve vaccination coverage, involving not only the general practitioner, but also other health providers, such as cardiologists, nurses, and pharmacists. This review first summarizes the pathophysiology of the interrelationships between inflammation, infection, and HF. Then, we describe the current clinical knowledge concerning the protective effect of vaccines against respiratory diseases (influenza, pneumococcal infection, and COVID-19) in patients with HF and finally we propose how vaccination coverage could be improved in these patients.

Published
2021
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70. Early Impact of Severe Acute Respiratory Syndrome Coronavirus 2 on Pediatric Clinical Research: A Pan-European and Canadian Snapshot in Time

Author

Mantha, Olivier L., primary, Flamein, Florence, additional, Turner, Mark A., additional, Fernandes, Ricardo M., additional, Hankard, Régis, additional, Ladenstein, Ruth, additional, Mikolasek, Andrea, additional, Christiaens, Daphné, additional, Degraeuwe, Eva, additional, Walle, Johan Vande, additional, Nuytinck, Lieve, additional, Mok, Elise, additional, Maguire, Jonathon L., additional, Lacaze-Masmonteil, Thierry, additional, Pokorna, Pavla, additional, Skovby, Pernille, additional, Rajasaar, Heli, additional, Kallio, Jaana, additional, Lepola, Pirkko, additional, Gras-Le Guen, Christele, additional, Gottrand, Frédéric, additional, Kaguelidou, Florentia, additional, Chevassus, Hugues, additional, Pin, Isabelle, additional, Rouger-Gaudichon, Jérémie, additional, Patel, Maya, additional, Neumann, Eva, additional, Schwab, Matthias, additional, Losifidis, Elias, additional, Roilides, Emmanuel, additional, Murray, Máiréad, additional, La Neve, Federica, additional, Rocchi, Francesca, additional, Hjelle, Sigrun Margrethe, additional, Halvorsen, Thomas, additional, Migdał, Marek, additional, Wiśniewski, Aleksander, additional, Cabrita, Inês Zimbarra, additional, Torrão, Rita Carilho, additional, Martins, Tiago, additional, Trasorras, Cristina Serén, additional, Martinón-Torres, Federico, additional, Rane, Anders, additional, Naumburg, Estelle, additional, Posfay-Barbe, Klara M., additional, Diezi, Manuel, additional, Paioni, Paolo, additional, Mahler, Fenna, additional, de Wildt, Saskia N., additional, Van der Geest, Tesa, additional, and Wilding, Karen, additional

Published
2021
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72. Long-term air pollution exposure, greenness and health-related quality of life (HRQOL) in ECRHS

Author

Siroux, Valerie, primary, Boudier, Anne, additional, Markevych, Iana, additional, Jacquemin, Bénédicte, additional, Abramson, Michael J, additional, Accordini, Simone, additional, Forsberg, Bertil, additional, Fuertes, Elaine, additional, Garcia-Aymerich, Judith, additional, Heinrich, Joachim, additional, Johanessen, Ane, additional, Leynaert, Bénédicte, additional, and Pin, Isabelle, additional

Published
2021
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73. Phenols, phthalates and thyroid hormone levels during pregnancy; relying on toxicological data and Adverse Outcome Pathways to inform epidemiological analysis

Author

Nakiwala, Dorothy, primary, Noyes, Pamela D., additional, Faure, Patrice, additional, Chovelon, Benoît, additional, Corne, Christelle, additional, Gauchez, Anne Sophie, additional, Guergour, Dorra, additional, Lyon Caen, Sarah, additional, Sakhi, Amrit K., additional, Sabaredzovic, Azemira, additional, Thomsen, Cathrine, additional, Pin, Isabelle, additional, Slama, Rémy, additional, and Philippat, Claire, additional

Published
2021
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76. Rapid Improvement after Starting Elexacaftor–Tezacaftor–Ivacaftor in Patients with Cystic Fibrosis and Advanced Pulmonary Disease

Author

Burgel, Pierre-Régis, primary, Durieu, Isabelle, additional, Chiron, Raphaël, additional, Ramel, Sophie, additional, Danner-Boucher, Isabelle, additional, Prevotat, Anne, additional, Grenet, Dominique, additional, Marguet, Christophe, additional, Reynaud-Gaubert, Martine, additional, Macey, Julie, additional, Mely, Laurent, additional, Fanton, Annlyse, additional, Quetant, Sébastien, additional, Lemonnier, Lydie, additional, Paillasseur, Jean-Louis, additional, Da Silva, Jennifer, additional, Martin, Clémence, additional, Andrejak, Claire, additional, Becourt, Arnaud, additional, Mounard, Julie, additional, Poulet, Claire, additional, Rames, Cinthia, additional, Talleux, Marie, additional, Chevalier, Marie-Chantal, additional, Darviot, Estelle, additional, Jouvenot, Marie, additional, Marien, Caroline, additional, Paris, Audrey, additional, Pelatan, Cécile, additional, Person, Christine, additional, Priou, Pascaline, additional, Troussier, Françoise, additional, Urban, Thierry, additional, Dalphin, Marie-Laure, additional, Dalphin, Jean-Charles, additional, Ladaurade, Alice, additional, Pernet, Didier, additional, Richaud-Thiriez, Bénédicte, additional, Roux-Claude, Pauline, additional, Blanc, Nathalia, additional, Boisserie-Lacroix, Vincent, additional, Bui, Stephanie, additional, Collet, Cyrielle, additional, Debelleix, Stéphane, additional, Bergot, Emmanuel, additional, Brouard, Jacques, additional, Campbell, Karine, additional, Laurans, Muriel, additional, Ribault, Virginie, additional, Borderon, Corinne, additional, Heraud, Marie-Christine, additional, Labbe, Guillaume, additional, Montcouquiol, Sylvie, additional, Petit, Isabelle, additional, Ruivard, Marc, additional, Delestrain, Céline, additional, Douvry, Benoit, additional, Epaud, Ralph, additional, Maitre, Bernard, additional, Remus, Natascha, additional, Beltramo, Guillaume, additional, Houzel, Anne, additional, Huet, Frédéric, additional, Perez, Stéphanie, additional, Boldron-Ghaddar, Amale, additional, Scalbert, Manuela, additional, Bouzioukh, Rabah, additional, Simon, Charles, additional, Camara, Boubou, additional, Hamidfar, Rébecca, additional, Llerena, Catherine, additional, Pin, Isabelle, additional, Deschildre, Antoine, additional, Gicquello, Alice, additional, Le Rouzic, Olivier, additional, Leroy, Clara, additional, Paris, Nicolas, additional, Perez, Thierry, additional, Thumerelle, Caroline, additional, Turck, Dominique, additional, Wizla, Nathalie, additional, Dupuy-Grasset, Magali, additional, Languepin, Jane, additional, Masson-Rouchaud, Alexandra, additional, Menetrey, Céline, additional, Durupt, Stéphane, additional, L’Excellent, Sophie, additional, Nove-Josserand, Raphaele, additional, Ohlmann, Camille, additional, Reix, Phillipe, additional, Reynaud, Quitterie, additional, Werck-Gallois, Marie-Christine, additional, Baravalle, Mélissandre, additional, Coltey, Bérangère, additional, Desmazes-Dufeu, Nadine, additional, Dubus, Jean-Christophe, additional, Gautier, Clarisse, additional, Rey, Jean-Baptiste, additional, Stremler, Nathalie, additional, Caimmi, Davide, additional, Devrait, Margot, additional, Moreau, Johan, additional, Billon, Yves, additional, Blondé, Aurore, additional, Guillaumot, Anne, additional, Kiefer, Sébastien, additional, Peretti, Laura, additional, Tatopoulos, Aurélie, additional, Tiotiu, Angélica, additional, Benhamida, Myriam, additional, Bihouee, Tiphaine, additional, Eschapasse, Emmanuel, additional, Tissot, Adrien, additional, Giannantonio, Marie, additional, Leroy, Sylvie, additional, Piccini-Bailly, Carole, additional, Pradelli, Johana, additional, Messika, Jonathan, additional, Boussaud, Véronique, additional, Burgel, Pierre-Régis, additional, Carlier, Nicolas, additional, Honoré, Isabelle, additional, Hubert, Dominique, additional, Kanaan, Reem, additional, Bailly-Botuha, Céline, additional, Chedevergne, Frédérique, additional, De Blic, Jacques, additional, Delacourt, Christophe, additional, Drummond, David, additional, Fauroux, Brigitte, additional, Karila, Chantal, additional, Le Bourgeois, Muriel, additional, Sermet, Isabelle, additional, Delaisi, Bertrand, additional, Gerardin, Michèle, additional, Houdouin, Veronique, additional, Leclainche, Laurence, additional, Aubertin, Guillaume, additional, Berdah, Laura, additional, Clement, Annick, additional, Corvol, Harriet, additional, Nathan, Nadia, additional, Prevost, Blandine, additional, Richard, Nicolas, additional, Tamalet, Aline, additional, Taytard, Jessica, additional, Thouvenin, Guillaume, additional, Tourniaire, Barbara, additional, Abely, Michel, additional, Bessaci-Kabouya, Katia, additional, Dury, Sandra, additional, Ravoninjatovo, Bruno, additional, Dabadie, Alain, additional, Dagorne, Michel, additional, Deneuville, Eric, additional, Jamin, Marie, additional, Ribault, Mélanie, additional, Vigier, Clémentine, additional, Belleguic, Chantal, additional, Brinchault, Graziella, additional, Desrues, Benoit, additional, Barzic, Audrey, additional, Dirou-Prigent, Anne, additional, Le Bihan, Jean, additional, Revert, Krista, additional, Ropars, Thomas, additional, Couderc, Laure, additional, Dominique, Stéphane, additional, Morisse-Pradier, Hélène, additional, Pramil, Stéphanie, additional, Thiberville, Luc, additional, Allou, Nathalie, additional, Enaud, Laurent, additional, Gachelin, Elsa, additional, Huchot, Eric, additional, Payet, Annabelle, additional, Perisson, Caroline, additional, Piyaraly, Saguiraly, additional, Valois, Sophie, additional, Herzog, Audrey, additional, Kessler, Romain, additional, Porzio, Michele, additional, Weiss, Laurence, additional, Beaumont, Laurence, additional, Brugiere, Olivier, additional, Colin, Sylvie, additional, Verdiere, de, additional, Cuquemelle, Elise, additional, De Miranda, Sandra, additional, Monem Hamid, Adbdul, additional, Parquin, François, additional, Picard, Clément, additional, Roux, Antoine, additional, Roy, Charlotte, additional, Bremont, François, additional, Didier, Alain, additional, Dupuis, Marion, additional, Faviez, Guillaume, additional, Labouret, Géraldine, additional, Mittaine, Marie, additional, Murris-Espin, Marlène, additional, Roditis, Léa, additional, Cosson, Laure, additional, Diot, Patrice, additional, Flament, Thomas, additional, Giraut, Charlotte, additional, Mankikian, Julie, additional, Arnouat, Baptiste, additional, Mousset, Gaétane, additional, Storni, Véronique, additional, Vigneron, Philippe, additional, Coirier-Duet, Emmanuelle, additional, and Gabsi, Asma, additional

Published
2021
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77. Comparison of a Barcode-Based Smartphone Application to a Questionnaire to Assess the Use of Cleaning Products at Home and Their Association with Asthma Symptoms

Author

Lemire, Pierre, Temam, Sofia, Quinot, Catherine, Sévin, Etienne, Remacle, Sophie, Supernant, Karine, Dumas, Orianne, Le Moual, Nicole, Eyriey, E., Licinia, A., Vellement, A., Pin, Isabelle, Hofmann, P., Hullo, Églantine, Llerena, Catherine, Morin, X., Morlot, A., Lepeule, Johanna, Lyon-Caen, Sarah, Philippat, Claire, Quentin, Joane, Siroux, Valérie, Slama, Rémy, Faraldo, Beatrice, Centre de recherche en épidémiologie et santé des populations (CESP), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Paul Brousse-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris-Saclay, MGEN Foundation for Public Health [Paris] (FESP-MGEN), Institute for Advanced Biosciences / Institut pour l'Avancée des Biosciences (Grenoble) (IAB), Centre Hospitalier Universitaire [Grenoble] (CHU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Etablissement français du sang - Auvergne-Rhône-Alpes (EFS)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA), EpiConcept [Paris], The Sepages Study Group., Fondation d’entreprise MGEN pour la santé publique (FESP MGEN), Anses-PNR-EST-2015-1-022/Ademe-1594C0091, Anses-PNR-EST-2017-1-101/Ademe-1762C0021 Seventh Framework Programme, FP7: FP7/2007-206, N308333-HELIX European Research Council, ERC: N 311765-E-DOHaD Agence Nationale de la Recherche, ANR: 14-CE21-0007-01, 19-CE36-0003-01, ANR 18-CE36-005, ANR-12-PDOC-0029-01, ANR-15-IDEX, ANR-15-IDEX-02 Institut National de la Santé et de la Recherche Médicale, Inserm Fondation de France: CLI-MATHES—00081169 Commissariat Général à l'Investissement, CGI Agence Nationale de Sécurité Sanitaire de l’Alimentation, de l’Environnement et du Travail, ANSES: PNR-EST-2018-1-264 Agir pour les Maladies Chroniques, Acknowledgments: We acknowledge the role of SEPAGES cohort study group: E. Eyriey, A. Licinia, A. Vellement (Groupe Hospitalier Mutualiste, Grenoble), I. Pin, P. Hofmann, E. Hullo, C. Llerena (Grenoble University Hospital, La Tronche), X. Morin (Clinique des Cèdres, Echirolles), A. Morlot (Clinique Belledonne, Saint-Martin d’Hères), J. Lepeule, S. Lyon-Caen, C. Philippat, I. Pin, J. Quentin, V. Siroux, R. Slama (Inserm, CNRS, University Grenoble Alpes IAB research center). We thank A. Benlakhryfa, L. Borges, Y. Gioria, clinical research assistants, J. Giraud, M. Marceau, M.-P. Martin, nurses, E. Charvet, A. Putod, midwives, M. Graca, K. Gridel, C. Pelini, fieldworkers, K. Guichardet, A. Levanic, C. Martel, E. Quinteiro neuropsychologists, the sta↵ from Grenoble Center for Clinical Investigation (CIC): J.-L. Cracowski, C. Cracowski, E. Hodaj, D. Abry, N. Gonnet and A. Tournier. A warm thank you also to M. Althuser, S. Althuser, F. Camus-Chauvet, P. Dusonchet, S. Dusonchet, L. Emery, P. Fabbrizio, P. Ho↵mann, D. Marchal André, X. Morin, E. Opoix, L. Pacteau, P. Rivoire, A. Royannais, C. Tomasella, T. Tomasella, D. Tournadre, P. Viossat, E. Volpi, S. Rey, E. Warembourg and clinicians from Grenoble University Hospital for their support in the recruitment of the study volunteers. We also thank A. Buchet, S.F. Caraby, J.-N. Canonica, J. Dujourdil, E. Eyriey, P. Hofmann, M. Jeannin, A. Licina, X. Morin, A. Nicolas, and all midwives from the four maternity wards of Grenoble urban areas. We thank B. Chevolon, C. Cornes, A.S. Gauchez, D. Guergour, P. Faure, J. Arnaud for thyroid hormones assessment. We thank the team of L. Chaperod (EFS) for its implication on the immunological aspects of the project. We thank G. Uzu (IRD) and J.-L. Ja↵rezo (CNRS) for their implication on PM oxidative potential assessment. We thank F.-X. Leupert, O. Bonnet and L. Goirand for the access to the birth certificate database from the Conseil Général de l’Isère. Sépages biospecimens are stored at Grenoble University Hospital (CHU-GA) biobank (bb-0033-00069), we would like to thank the whole CRB team, led by P. Mossuz and P. Lorimier, and in particular the technicians for the huge work of biospecimens processing and pooling: W. Jayar and L. Than, as well as G. Schummer. The Internet platform for secured data collection was developed by Epiconcept Paris (E. Sevin, S. Ployart, A. Polaert). SEPAGES data are stored thanks to Inserm RE-CO-NAI platform funded by Commissariat Général à l’Investissement, with the implication of Sophie de Visme (Inserm DSI). Many thanks to M.A. Charles, RE-CO-NAI coordinator, for her support. Finally, and importantly, we would like to express our sincere thanks to participants of the SEPAGES study. The authors are grateful for the help received from Ines Taarit and Mathias Clément to update the cleaning products ingredients database., Funding: The cohort was supported by the European Research Council (consolidator grant N 311765-E-DOHaD, PI, R. Slama), by the European Community’s Seventh Framework Programme (FP7/2007-206, grant N308333-HELIX, PI, M. Vrijheid), by ANR, the French Research Agency (PAPER project ANR-12-PDOC-0029-01, PI, J. Lepeule, SHALCOH project, 14-CE21-0007-01, PI, R. Slama, GUMME project, PI, R. Slama, ETAPE ANR 18-CE36-005, PI, J. Lepeule, EDeN project 19-CE36-0003-01, SYMER project, ANR-15-IDEX-02, PI, U. Schlattner, Mobil’Air project, ANR-15-IDEX, PI, S. Mathy, supported by University Grenoble-3Alpes), by ANSES (CNAP and HYPAXE projects, PI C. Philippat, PENDORE project, PNR-EST-2018-1-264, PI, V. Siroux), by Plan Cancer (Canc’Air project, PI, P. Guénel), by Association de Recherche sur le Cancer (ARC, PI, P. Guénel), by AGIR pour les maladies chroniques (PI, R. Slama and PRENAPAR project, V. Siroux), and Fonds de Recherche pour la Santé Respiratoire (FRSR, PI, I. Pin) and by Fondation de France (CLI-MATHES—00081169, J. Lepeule). We acknowledge the support of ANSES, Inserm and AGIR pour les maladies chroniques, for SEPAGES feasibility study. The support of 'SCUSI 2017' Région Auvergne-Rhône-Alpes programme is also acknowledged. COBANET-Sepages project was support by Anses and Ademe (COBANET: Anses-PNR-EST-2015-1-022/Ademe-1594C0091, PI: N Le Moual, CRESPINET: Anses-PNR-EST-2017-1-101/Ademe-1762C0021, PI: N Le Moual). Pierre Lemire benefited from a PhD scholarship of the University of Paris-Sud/Paris-Saclay, France., The cohort was supported by the European Research Council (consolidator grant N 311765-E-DOHaD, PI, R. Slama), by the European Community?s Seventh Framework Programme (FP7/2007-206, grant N308333-HELIX, PI, M. Vrijheid), by ANR, the French Research Agency (PAPER project ANR-12-PDOC-0029-01, PI, J. Lepeule, and EDeN project 19-CE36-0003-01, SYMER project, ANR-15-IDEX-02, PI, U. Schlattner, Mobil?Air project, ANR-15-IDEX, PI, S. Mathy, supported by University Grenoble-3Alpes), by ANSES (CNAP and HYPAXE projects, PI C. Philippat, PENDORE project, PNR-EST-2018-1-264, PI, V. Siroux), by Plan Cancer (Canc?Air project, PI, P. Gu?nel), by Association de Recherche sur le Cancer (ARC, PI, P. Gu?nel), by AGIR pour les maladies chroniques (PI, R. Slama and PRENAPAR project, V. Siroux), and Fonds de Recherche pour la Sant? Respiratoire (FRSR, PI, I. Pin) and by Fondation de France (CLIMATHES?00081169, J. Lepeule). We acknowledge the support of ANSES, Inserm and AGIR pour les maladies chroniques, for SEPAGES feasibility study. The support of ?SCUSI 2017? R?gion Auvergne-Rh?ne-Alpes programme is also acknowledged. COBANET-Sepages project was support by Anses and Ademe (COBANET: Anses-PNR-EST-2015-1-022/Ademe-1594C0091, PI: N Le Moual

Subjects
medicine.medical_specialty, Health, Toxicology and Mutagenesis, [SDV]Life Sciences [q-bio], lcsh:Medicine, Smartphone application, Logistic regression, Article, 03 medical and health sciences, 0302 clinical medicine, Surveys and Questionnaires, Environmental health, Epidemiology, Odds Ratio, medicine, Humans, 030212 general & internal medicine, Association (psychology), smartphone application, Asthma, household cleaning products, business.industry, lcsh:R, Public Health, Environmental and Occupational Health, Asthma symptoms, Odds ratio, asthma, medicine.disease, 3. Good health, 030228 respiratory system, [SDV.SPEE] Life Sciences [q-bio]/Santé publique et épidémiologie, Female, [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie, Smartphone, business, Kappa, Disinfectants
Abstract

International audience; Household disinfectant and cleaning products (HDCPs) assessment is challenging in epidemiological research. We hypothesized that a newly-developed smartphone application was more objective than questionnaires in assessing HDCPs. Therefore, we aimed to compare both methods, in terms of exposure assessments and respiratory health effects estimates. The women of the SEPAGES birth cohort completed repeated validated questionnaires on HDCPs and respiratory health and used an application to report HDCPs and scan products barcodes, subsequently linked with an ingredients database. Agreements between the two methods were assessed by Kappa coefficients. Logistic regression models estimated associations of HDCP with asthma symptom score. The 101 participants (18 with asthma symptom score ≥1) scanned 617 different products (580 with available ingredients list). Slight to fair agreements for sprays, bleach and scented HDCP were observed (Kappa: 0.35, 0.25, 0.11, respectively). Strength of the associations between HDCP and asthma symptom score varied between both methods but all odds ratios (OR) were greater than one. The number of scanned products used weekly was significantly associated with the asthma symptom score (adjusted-OR [CI 95%]: 1.15 [1.00–1.32]). This study shows the importance of using novel tools in epidemiological research to objectively assess HDCP and therefore reduce exposure measurement errors.

Published
2021
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78. Cumulative Occupational Exposures and Lung Function Decline in Two Large General Population Cohorts

Author

Lytras, Theodore, Beckmeyer-Borowko, Anna, Kogevinas, Manolis, Kromhout, Hans, Carsin, Anne-Elie, Antó, Josep Maria, Bentouhami, Hayat, Weyler, Joost, Heinrich, Joachim, Nowak, Dennis, Urrutia, Isabel, Martínez-Moratalla, Jesús, Gullón, José Antonio, Pereira Vega, Antonio, Raherison Semjen, Chantal, Pin, Isabelle, Demoly, Pascal, Leynaert, Bénédicte, Villani, Simona, Gislason, Thorarinn, Svanes, Øistein, Holm, Mathias, Forsberg, Bertil, Norbäck, Dan, Mehta, Amar J, Keidel, Dirk, Vernez, David, Benke, Geza, Jõgi, Rain, Torén, Kjell, Sigsgaard, Torben, Schlünssen, Vivi, Olivieri, Mario, Blanc, Paul D, Watkins, John, Bono, Roberto, Squillacioti, Giulia, Buist, A Sonia, Vermeulen, Roel, Jarvis, Deborah, Probst-Hensch, Nicole, Zock, Jan-Paul, Lytras, Theodore, Beckmeyer-Borowko, Anna, Kogevinas, Manolis, Kromhout, Hans, Carsin, Anne-Elie, Antó, Josep Maria, Bentouhami, Hayat, Weyler, Joost, Heinrich, Joachim, Nowak, Dennis, Urrutia, Isabel, Martínez-Moratalla, Jesús, Gullón, José Antonio, Pereira Vega, Antonio, Raherison Semjen, Chantal, Pin, Isabelle, Demoly, Pascal, Leynaert, Bénédicte, Villani, Simona, Gislason, Thorarinn, Svanes, Øistein, Holm, Mathias, Forsberg, Bertil, Norbäck, Dan, Mehta, Amar J, Keidel, Dirk, Vernez, David, Benke, Geza, Jõgi, Rain, Torén, Kjell, Sigsgaard, Torben, Schlünssen, Vivi, Olivieri, Mario, Blanc, Paul D, Watkins, John, Bono, Roberto, Squillacioti, Giulia, Buist, A Sonia, Vermeulen, Roel, Jarvis, Deborah, Probst-Hensch, Nicole, and Zock, Jan-Paul

Abstract

RATIONALE: Few longitudinal studies have assessed the relationship between occupational exposures and lung function decline in the general population, with sufficiently long follow-up.OBJECTIVES: Our objective was to examine this potential association in two large cohorts (ECRHS and SAPALDIA).METHODS: General population samples aged 18 to 62 were randomly selected in 1991-1993, and followed up approximately 10 and 20 years later. Spirometry (without bronchodilation) was performed at each visit. Coded complete job histories during follow-up visits were linked to a Job-Exposure Matrix, generating cumulative exposure estimates for 12 occupational exposures. FEV1 and FVC were jointly modelled in linear mixed-effects models, fitted in a Bayesian framework, taking into account age and smoking.RESULTS: A total of 40,024 lung function measurements from 17,833 study participants were analyzed. We found accelerated declines in FEV1 and the FEV1/FVC ratio for exposure to biological dust, mineral dust and metals (FEV1 -15.1ml, -14.4ml and -18.7ml respectively, and FEV1/FVC -0.52%, -0.43% and -0.36% respectively, per 25 intensity-years of exposure). These declines were comparable in magnitude to those associated with long-term smoking. No effect modification by sex or smoking status was identified. Findings were similar between the ECRHS and SAPALDIA cohorts.CONCLUSIONS: Our results greatly strengthen the evidence base implicating occupation, independent of smoking, as a risk factor for lung function decline. This highlights the need to prevent or control these exposures in the workplace.

Published
2021

79. Ultraviolet radiation as a predictor of sex hormone levels in postmenopausal women : A European multi-center study (ECRHS)

Author

Triebner, Kai, Bifulco, Ersilia, Barrera-Gómez, José, Basagaña, Xavier, Benediktsdóttir, Bryndís, Forsberg, Bertil, Franklin, Karl A., Garcia-Larsen, Vanessa, Leynaert, Bénédicte, Lindberg, Eva, Martínez-Moratalla, Jesús, Muniozguren-Agirre, Nerea, Pin, Isabelle, Raherison, Chantal, Pereira-Vega, Antonio, Schlünssen, Vivi, Valentin, Antonia, Hustad, Steinar, Gómez Real, Francisco, Dadvand, Payam, Triebner, Kai, Bifulco, Ersilia, Barrera-Gómez, José, Basagaña, Xavier, Benediktsdóttir, Bryndís, Forsberg, Bertil, Franklin, Karl A., Garcia-Larsen, Vanessa, Leynaert, Bénédicte, Lindberg, Eva, Martínez-Moratalla, Jesús, Muniozguren-Agirre, Nerea, Pin, Isabelle, Raherison, Chantal, Pereira-Vega, Antonio, Schlünssen, Vivi, Valentin, Antonia, Hustad, Steinar, Gómez Real, Francisco, and Dadvand, Payam

Abstract

Background: Solar ultraviolet radiation (UVR) affects the body through pathways that exhibit positive as well as negative health effects such as immunoregulation and vitamin D production. Different vitamin D metabolites are associated with higher or lower concentrations of estrogens and may thus alter the female sex hormone balance. Objective: To study whether exposure to UVR, as a modifiable lifestyle factor, is associated with levels of sex hormones (17β-estradiol, estrone, estrone 3-sulfate, testosterone, dehydroepiandrosterone sulfate), gonadotropins (follicle stimulating hormone, luteinizing hormone) as well as sex hormone binding globulin in postmenopausal women, and thus investigate whether managing UVR exposure can influence the hormone balance, with potential benefits for the biological aging process. Methods: The study included 580 postmenopausal women from six European countries, participating in the European Community Respiratory Health Survey (2010–2014). Average UVR exposure during the month before blood sampling was estimated based on personal sun behavior and ambient levels. Hormone concentrations were measured in serum using state-of-the-art methods. Subsequently we applied linear mixed-effects models, including center as random intercept, hormone concentrations (one at a time) as outcome and UVR, age, skin type, body mass index, vitamin D from dietary sources, smoking, age at completed full-time education and season of blood sampling as fixed-effect predictors. Results: One interquartile range increase in UVR exposure was associated with decreased levels of 17β-estradiol (-15.6 pmol/L, 95 % Confidence Interval (CI): -27.69, -3.51) and estrone (-13.36 pmol/L, 95 % CI: -26.04, -0.68) and increased levels of follicle stimulating hormone (9.34IU/L, 95 % CI: 2.91, 15.77) and luteinizing hormone (13.86 IU/daL, 95 % CI: 2.48, 25.25). Conclusions: Exposure to UVR is associated with decreased estrogens and increased gonadotropins in postmenopausal women, a

Published
2021
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80. Cumulative Occupational Exposures and Lung Function Decline in Two Large General Population Cohorts

Author

IRAS OH Epidemiology Chemical Agents, dIRAS RA-2, Dep IRAS, Lytras, Theodore, Beckmeyer-Borowko, Anna, Kogevinas, Manolis, Kromhout, Hans, Carsin, Anne-Elie, Antó, Josep Maria, Bentouhami, Hayat, Weyler, Joost, Heinrich, Joachim, Nowak, Dennis, Urrutia, Isabel, Martínez-Moratalla, Jesús, Gullón, José Antonio, Pereira Vega, Antonio, Raherison Semjen, Chantal, Pin, Isabelle, Demoly, Pascal, Leynaert, Bénédicte, Villani, Simona, Gislason, Thorarinn, Svanes, Øistein, Holm, Mathias, Forsberg, Bertil, Norbäck, Dan, Mehta, Amar J, Keidel, Dirk, Vernez, David, Benke, Geza, Jõgi, Rain, Torén, Kjell, Sigsgaard, Torben, Schlünssen, Vivi, Olivieri, Mario, Blanc, Paul D, Watkins, John, Bono, Roberto, Squillacioti, Giulia, Buist, A Sonia, Vermeulen, Roel, Jarvis, Deborah, Probst-Hensch, Nicole, Zock, Jan-Paul, IRAS OH Epidemiology Chemical Agents, dIRAS RA-2, Dep IRAS, Lytras, Theodore, Beckmeyer-Borowko, Anna, Kogevinas, Manolis, Kromhout, Hans, Carsin, Anne-Elie, Antó, Josep Maria, Bentouhami, Hayat, Weyler, Joost, Heinrich, Joachim, Nowak, Dennis, Urrutia, Isabel, Martínez-Moratalla, Jesús, Gullón, José Antonio, Pereira Vega, Antonio, Raherison Semjen, Chantal, Pin, Isabelle, Demoly, Pascal, Leynaert, Bénédicte, Villani, Simona, Gislason, Thorarinn, Svanes, Øistein, Holm, Mathias, Forsberg, Bertil, Norbäck, Dan, Mehta, Amar J, Keidel, Dirk, Vernez, David, Benke, Geza, Jõgi, Rain, Torén, Kjell, Sigsgaard, Torben, Schlünssen, Vivi, Olivieri, Mario, Blanc, Paul D, Watkins, John, Bono, Roberto, Squillacioti, Giulia, Buist, A Sonia, Vermeulen, Roel, Jarvis, Deborah, Probst-Hensch, Nicole, and Zock, Jan-Paul

Published
2021

82. Interaction between gas cooking and GSTM1 null genotype in bronchial responsiveness: results from the European Community Respiratory Health Survey

Author

Amaral, André F S, Ramasamy, Adaikalavan, Castro-Giner, Francesc, Minelli, Cosetta, Accordini, Simone, Sørheim, Inga-Cecilie, Pin, Isabelle, Kogevinas, Manolis, Jõgi, Rain, Balding, David J, Norbäck, Dan, Verlato, Giuseppe, Olivieri, Mario, Probst-Hensch, Nicole, Janson, Christer, Zock, Jan-Paul, Heinrich, Joachim, and Jarvis, Deborah L

Published
2014
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83. Profile of exposures and lung function in adults with asthma: An exposome approach in the EGEA study

Author

Guillien, Alicia, primary, Lepeule, Johanna, additional, Seyve, Emie, additional, Le Moual, Nicole, additional, Pin, Isabelle, additional, Degano, Bruno, additional, Garcia-Aymerich, Judith, additional, Pépin, Jean-Louis, additional, Pison, Christophe, additional, Dumas, Orianne, additional, Varraso, Raphaëlle, additional, and Siroux, Valérie, additional

Published
2021
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84. Factors Associated with Asthma Severity in Children: Data from the French COBRAPed Cohort

Author

Lezmi, Guillaume, primary, Lejeune, Stéphanie, additional, Pin, Isabelle, additional, Blanchon, Sylvain, additional, Bouazza, Naïm, additional, Jolaine, Valérie, additional, Marguet, Christophe, additional, Houdoin, Véronique, additional, Berger, Patrick, additional, Fayon, Michael, additional, Dubus, Jean-Christophe, additional, Reix, Philippe, additional, Pellan, Mathieu, additional, Brouard, Jacques, additional, Chiron, Raphael, additional, Giovannini-Chami, Lisa, additional, Deschildre, Antoine, additional, de Blic, Jacques, additional, Abou-Taam, Rola, additional, Le Bourgeois, Muriel, additional, Hadchouel-Duvergé, Alice, additional, Drummond, David, additional, Delacourt, Christophe, additional, Alyanakian, Marie-Alexandra, additional, Chatennoud, Lucienne, additional, Thumerelle, Caroline, additional, Mordacq, Clémence, additional, Badiu-Decleyre, Irina, additional, Bonnel, Cécile, additional, Delbecque, Laure, additional, Beghin, Laurent, additional, Mingardi, Graziella, additional, Tournegros, Caroline, additional, Roditis, Léa, additional, Wanin, Stéphanie, additional, Lebras, Marie Noelle, additional, Debelleix, Stéphane, additional, Siao, Valérie, additional, Servat, Marine, additional, Simon, Guillaume, additional, El Boustany, Patricia, additional, Bosdure, Emmanuelle, additional, Mazenq, Julie, additional, Cabon, Isabelle, additional, Ohlmann, Camille, additional, Vrielynck, Stéphanie, additional, Jubin, Virginie, additional, André Gomez, Sylvie-Anne, additional, and Werck Gallois, Marie-Christine, additional

Published
2021
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85. Associations between specific IgE sensitization to 26 respiratory allergen molecules and HLA class II alleles in the EGEA cohort

Author

Gheerbrant, Hubert, primary, Guillien, Alicia, additional, Vernet, Raphaël, additional, Lupinek, Christian, additional, Pison, Christophe, additional, Pin, Isabelle, additional, Demenais, Florence, additional, Nadif, Rachel, additional, Bousquet, Jean, additional, Pickl, Winfried F., additional, Valenta, Rudolf, additional, Bouzigon, Emmanuelle, additional, and Siroux, Valérie, additional

Published
2021
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86. Evidence for linkage of a new region (11p14) to eczema and allergic diseases

Author

Guilloud-Bataille, Michel, Bouzigon, Emmanuelle, Annesi-Maesano, Isabella, Bousquet, Jean, Charpin, Denis, Gormand, Frédéric, Hochez, Joëlle, Just, Jocelyne, Lemainque, Arnaud, Le Moual, Nicole, Matran, Régis, Neukirch, Françoise, Oryszczyn, Marie-Pierre, Paty, Evelyne, Pin, Isabelle, Vervloet, Daniel, Kauffmann, Francine, Lathrop, Mark, Demenais, Florence, and Dizier, Marie-Hélène

Published
2008
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87. Effect of 17q21 variants and smoking exposure in early-onset asthma

Author

Bouzigon, Emmanuelle, Corda, Eve, Aschard, Hughes, Dizier, Marie-Helene, Boland, Anne, Bousquet, Jean, Chateigner, Nicolas, Gormand, Frederic, Just, Jocelyne, Le Moual, Nicole, Scheinmann, Pierre, Siroux, Valerie, Vervloet, Daniel, Zelenika, Diana, Pin, Isabelle, Kauffmann, Francine, Lathrop, Mark, and Demenais, Florence

Subjects
Human chromosome 21 -- Research, Asthma -- Risk factors, Asthma -- Causes of, Tobacco products -- Health aspects
Abstract

A study was conducted to establish an association between variants at chromosome 17q21 as well as exposure to smoking on early onset of asthma. Results indicated that there is an increased risk of early-onset asthma due to 17q21 chromosome variants and also exposure to tobacco products.

Published
2008

89. Regular physical activity levels and incidence of restrictive spirometry pattern: a longitudinal analysis of two population-based cohorts

Author

Carsin, Anne-Elie, Keidel, Dirk, Fuertes, Elaine, Imboden, Medea, Weyler, Joost, Nowak, Dennis, Heinrich, Joachim, Pascual Erquicia Silvia, Martinez-Moratalla, Jesus, Huerta, Ismael, Sanchez, Jose-Luis, Schaffner, Emmanuel, Caviezel, Serena, Beckmeyer-Borowko, Anna, Raherison, Chantal, Pin, Isabelle, Demoly, Pascal, Leynaert, Bénédicte, Cerveri, Isa, Squillacioti, Giulia, Accordini, Simone, Gislason, Thorarinn, Svanes, Cecilie, Toren, Kjell, Forsberg, Bertil, Janson, Christer, Jogi, Rain, Emtner, Margareta, Gómez Real Francisco, Jarvis, Debbie, Guerra, Stefano, Dharmage Shyamali, C, Probst-Hensch, Nicole, Garcia-Aymerich, Judith, and European Union's Horizon 2020 research and innovation programme

Subjects
BMI, FVC, Physical activity, restrictive spirometry, spirometry, Adult, Aged, 80 and over, Male, Epidemiology, Incidence, Vital Capacity, physical activity, Middle Aged, Respiration Disorders, Europe, Forced Expiratory Volume, Humans, Female, Longitudinal Studies, Exercise, 01 Mathematical Sciences, 11 Medical and Health Sciences, Aged
Abstract

A restrictive spirometry pattern is associated with high morbidity and mortality. Whether practicing regular physical activity protects against this pattern has never been studied. We estimated the association between regular physical activity and the incidence of restrictive spirometry pattern. Forced expiratory volume in 1 second (FEV1), forced vital capacity (FVC) and physical activity were assessed between 2000–2002 in the ECRHS (n=2,757, 39-67 years) and SAPALDIA (n=2,610, 36–82 years) population-based European cohorts, and again approximately 10-years later (2010–2013). Subjects with restrictive or obstructive spirometry pattern at baseline were excluded. We assessed the association of being active at baseline (defined as being physically active ≥2-3 times/wk for ≥1 h) with restrictive spirometry pattern at follow-up (defined as a post-bronchodilator FEV1/FVC ≥Lower Limit of Normal and FVC

Published
2020

90. Use of personal care products during pregnancy in relation to urinary concentrations of select phenols: A longitudinal analysis from the SEPAGES feasibility study

Author

Nakiwala, Dorothy, Vernet, Céline, Lyon-Caen, Sarah, Lavorel, Anna, Rolland, Matthieu, Cracowski, Claire, Pin, Isabelle, Calafat, Antonia, Slama, Rémy, Philippat, Claire, Eyriey, E., Licinia, A., Vellement, A., Hoffmann, P., Hullo, E., Llerena, C., Morin, X., Morlot, A., Lepeule, J., Quentin, J., Siroux, V., Institute for Advanced Biosciences / Institut pour l'Avancée des Biosciences (Grenoble) (IAB), Etablissement français du sang - Auvergne-Rhône-Alpes (EFS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre Hospitalier Universitaire [Grenoble] (CHU)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA), Service d'hospitalisation Urgences Pneumologiques - Mucoviscidose Adulte, Université Joseph Fourier - Grenoble 1 (UJF)-CHU Grenoble-Hôpital Michallon, Centers for Disease Control and Prevention [Atlanta] (CDC), Centers for Disease Control and Prevention, Philippat, Claire, and Centre Hospitalier Universitaire [Grenoble] (CHU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Etablissement français du sang - Auvergne-Rhône-Alpes (EFS)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA)

Subjects
[SDV.EE.SANT]Life Sciences [q-bio]/Ecology, environment/Health, [SDV.SPEE] Life Sciences [q-bio]/Santé publique et épidémiologie, Benzophenone-3, Personal care products, Pregnant women, [SDV.EE.SANT] Life Sciences [q-bio]/Ecology, environment/Health, Parabens, [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie, Bisphenols, Endocrine disruptors
Abstract

International audience; Background: Exposure to certain synthetic phenols is of growing concern, in particular among pregnant women, because of their endocrine disrupting nature. Many phenols are still authorized in personal care products (PCP). We aimed to assess if use of PCPs, by pregnant women could influence their urinary concentrations of synthetic phenols.Methods: We used a panel design with intense urine sample collection. Eight women completed a diary with exact time and use of PCPs in three weeks. We measured the concentrations of phenols (four parabens, bisphenol A and S, two dichlorophenols, triclosan, and benzophenone-3) in 178 urine samples, collected during 7 consecutive days at 3 time points during pregnancy. We characterized PCP use as the total number of PCP applications or as a single PCP use (yes/no) in three time windows (0–6, 6 to 12 and 12 to 24h before each urine sample collection). We used adjusted linear and Tobit regressions to assess associations between PCP use and phenol urinary concentrations.Results: The total number of PCP applications was positively associated with ethylparaben, propylparaben and butylparaben concentrations. We observed a peak in urinary concentration of ethylparaben, butylparaben and propylparaben at 2.86, 2.55 and 2.67 h since last PCP use, respectively and twelve different types of PCPs were positively associated with at least one of these parabens. The bisphenol S concentration increased by 12.4% (95%CI: confidence interval: 5.9; 19.3) for each additional PCP application in the 12 to 24 time window and use of specific PCPs such as anti-stretchmarks cream, facial cleanser and shower gel. Associations varied by time window.Conclusion: Our study showed that PCP use was associated with a short-term increase in the urinary concentration of ethylparaben, butylparaben and propylparaben, but not methylparaben. This study also reported a positive association between the use of PCPs and the bisphenol S concentration, a finding that warrants further investigation in cohorts with repeated collection of urine samples and detailed information on PCP use.

Published
2020
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91. Regular Physical Activity Levels and Incidence of Restrictive Spirometry Pattern : A Longitudinal Analysis of 2 Population-Based Cohorts

Author

Carsin, Anne-Elie, Keidel, Dirk, Fuertes, Elaine, Imboden, Medea, Weyler, Joost, Nowak, Dennis, Heinrich, Joachim, Pascual Erquicia, Silvia, Martinez-Moratalla, Jesus, Huerta, Ismael, Sanchez, Jose-Luis, Schaffner, Emmanuel, Caviezel, Seraina, Beckmeyer-Borowko, Anna, Raherison, Chantal, Pin, Isabelle, Demoly, Pascal, Leynaert, Bénédicte, Cerveri, Isa, Squillacioti, Giulia, Accordini, Simone, Gislason, Thorarinn, Svanes, Cecilie, Toren, Kjell, Forsberg, Bertill, Janson, Christer, Jögi, Rain, Emtner, Margareta, Gómez Real, Francisco, Jarvis, Debbie, Guerra, Stefano, Dharmage, Shyamali C., Probst-Hensch, Nicole, Garcia-Aymerich, Judith, Carsin, Anne-Elie, Keidel, Dirk, Fuertes, Elaine, Imboden, Medea, Weyler, Joost, Nowak, Dennis, Heinrich, Joachim, Pascual Erquicia, Silvia, Martinez-Moratalla, Jesus, Huerta, Ismael, Sanchez, Jose-Luis, Schaffner, Emmanuel, Caviezel, Seraina, Beckmeyer-Borowko, Anna, Raherison, Chantal, Pin, Isabelle, Demoly, Pascal, Leynaert, Bénédicte, Cerveri, Isa, Squillacioti, Giulia, Accordini, Simone, Gislason, Thorarinn, Svanes, Cecilie, Toren, Kjell, Forsberg, Bertill, Janson, Christer, Jögi, Rain, Emtner, Margareta, Gómez Real, Francisco, Jarvis, Debbie, Guerra, Stefano, Dharmage, Shyamali C., Probst-Hensch, Nicole, and Garcia-Aymerich, Judith

Abstract

We estimated the association between regular physical activity and the incidence of restrictive spirometry pattern. Forced expiratory volume in 1 second (FEV1), forced vital capacity (FVC), and physical activity were assessed in 2 population-based European cohorts (European Community Respiratory Health Survey: n = 2,757, aged 39-67 years; and Swiss Study on Air Pollution and Lung and Heart Diseases in Adults: n = 2,610, aged 36-82 years) first in 2000-2002 and again approximately 10 years later (2010-2013). Subjects with restrictive or obstructive spirometry pattern at baseline were excluded. We assessed the association of being active at baseline (defined as being physically active at least 2-3 times/week for ≥1 hour) with restrictive spirometry pattern at follow-up (defined as a postbronchodilation FEV1/FVC ratio of at least the lower limit of normal and FVC of <80% predicted) using modified Poisson regression, adjusting for relevant confounders. After 10 years of follow-up, 3.3% of participants had developed restrictive spirometry pattern. Being physically active was associated with a lower risk of developing this phenotype (relative risk = 0.76, 95% confidence interval: 0.59, 0.98). This association was stronger among those who were overweight and obese than among those of normal weight (P for interaction = 0.06). In 2 large European studies, adults practicing regular physical activity were at lower risk of developing restrictive spirometry pattern over 10 years.

Published
2020
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92. Physical activity and lung function-Cause or consequence?

Author

Bedard, Annabelle, Carsin, Anne-Elie, Fuertes, Elaine, Accordini, Simone, Dharmage, Shyamali C., Garcia-Larsen, Vanessa, Heinrich, Joachim, Janson, Christer, Johannessen, Ane, Leynaert, Benedicte, Luis Sanchez-Ramos, Jose, Peralta, Gabriela P., Pin, Isabelle, Squillacioti, Giulia, Weyler, Joost, Jarvis, Deborah, Garcia-Aymerich, Judith, Bedard, Annabelle, Carsin, Anne-Elie, Fuertes, Elaine, Accordini, Simone, Dharmage, Shyamali C., Garcia-Larsen, Vanessa, Heinrich, Joachim, Janson, Christer, Johannessen, Ane, Leynaert, Benedicte, Luis Sanchez-Ramos, Jose, Peralta, Gabriela P., Pin, Isabelle, Squillacioti, Giulia, Weyler, Joost, Jarvis, Deborah, and Garcia-Aymerich, Judith

Abstract

Concerns exist that the positive association of physical activity with better lung function, which has been suggested in previous longitudinal studies in smokers, is due to reverse causation. To investigate this, we applied structural equation modeling (SEM), an exploratory approach, and marginal structural modeling (MSM), an approach from the causal inference framework that corrects for reverse causation and time-dependent confounding and estimates causal effects, on data from participants in the European Community Respiratory Health Survey (ECRHS, a multicentre European cohort study initiated in 1991-1993 with ECRHS I, and with two follow-ups: ECRHS II in 1999-2003, and ECRHS III in 2010-2014). 753 subjects who reported current smoking at ECRHS II, with repeated data on lung function at ECRHS I, II and III, physical activity at ECRHS II and III, and potential confounders at ECRHS I and II, were included in the analyses. SEM showed positive associations between physical activity and lung function in both directions. MSM suggested a protectivecausaleffect of physical activity on lung function (overall difference in mean beta (95% CI), comparing active versus non-active individuals: 58 mL (21-95) for forced expiratory volume in one second and 83 mL (36-130) for forced vital capacity). Our results suggest bi-directional causation and support a true protective effect of physical activity on lung function in smokers, after accounting for reverse causation and time-dependent confounding.

Published
2020
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93. Is diet partly responsible for differences in COVID-19 death rates between and within countries?

Author

Bousquet, Jean, Anto, Josep M., Iaccarino, Guido, Czarlewski, Wienczyslawa, Haahtela, Tari, Anto, Aram, Akdis, Cezmi, Blain, Hubert, Canonica, G. Walter, Cardona, Victoria, Cruz, Alvaro A., Illario, Maddalena, Ivancevich, Juan Carlos, Jutel, Marek, Klimek, Ludger, Kuna, Piotr, Laune, Daniel, Larenas-linnemann, Désirée, Mullol, Joaquim, Papadopoulos, Nikos G., Pfaar, Oliver, Samolinski, Boleslaw, Valiulis, Arunas, Yorgancioglu, Arzu, Zuberbier, Torsten, Latiff, Amir, Abdullah, Baharudin, Aberer, Werner, Abusada, Nancy, Adcock, Ian, Afani, Alejandro, Agache, Ioana, Aggelidis, Xenofon, Agustin, Jenifer, Akdis, Mübeccel, Al-Ahmad, Mona, Bassam, Abou Al Zahab, Aldrey-Palacios, Oscar, Cuesta, Emilio Alvarez, Alzaabi, Ashraf, Amad, Salma, Ambrocio, Gene, Annesi-Maesano, Isabella, Ansotegui, Ignacio, Anto, Josep, Arshad, Hasan, Artesani, Maria Cristina, Asayag, Estrella, Avolio, Francesca, Azhari, Khuzama, Baiardini, Ilaria, Bajrović, Nissera, Bakakos, Petros, Mongono, Sergio Bakeyala, Balotro-Torres, Christine, Barba, Sergio, Barbara, Cristina, Barbosa, Elsa, Barreto, Bruno, Bartra, Joan, Bateman, Eric D., Battur, Lkhagvaa, Bedbrook, Anna, Barajas, Martín Bedolla, Beghé, Bianca, Bel, Elizabeth, Kheder, Ali Ben, Benson, Mikael, Berghea, Camelia, Bergmann, Karl Christian, Bernstein, David, Bewick, Mike, Bialek, Slawomir, Białoszewski, Artur, Bieber, Thomas, Billo, Nils, Bilo, Maria Beatrice, Bindslev-Jensen, Carsten, Bjermer, Leif, Marciniak, Malgorzata Bochenska, Bond, Christine, Boner, Attilio, Bonini, Matteo, Bonini, Sergio, Bosnic-Anticevich, Sinthia, Bosse, Isabelle, Botskariova, Sofia, Bouchard, Jacques, Boulet, Louis Philippe, Bourret, Rodolphe, Bousquet, Philippe, Braido, Fulvio, Briggs, Andrew, Brightling, Christopher, Brozek, Jan, Buhl, Roland, Bumbacea, Roxana, Cabañas, María Teresa Burguete, Bush, Andrew, Busse, William W., Buters, Jeroen, Caballero-Fonseca, Fernan, Calderon, Moïses A., Calvo, Mario, Camargos, Paulo, Camuzat, Thierry, Cano, Antonio, Capriles-Hulett, Arnaldo, Caraballo, Luis, Cardona, Vicky, Carlsen, Kai Hakon, Caro, Jorge, Carreon-Asun-cion, Fredelita, Carriazo, Ana Maria, Casale, Thomas, Castor, Mary Ann, Castro, Elizabeth, Cecchi, Lorenzo, Sarabia, Alfonso Cepeda, Chandrasekharan, Ramanathan, Chang, Yoon Suk, Chato-Andeza, Victoria, Chatzi, Lida, Chatzidaki, Christina, Chavannes, Niels H., Chen, Yuzhi, Cheng, Lei, Chivato, Tomas, Chkhartishvili, Ekaterine, Christoff, George, Chrystyn, Henry, Chu, Derek K., Chua, Antonio, Chuchalin, Alexander, Chung, Kian Fan, Cicerán, Alberto, Cingi, Cemal, Ciprandi, Giorgio, Cirule, Ieva, Coelho, Ana Carla, Constantinidis, Jannis, de Sousa, Jaime Correia, Costa, Elisio, Costa, David, Domínguez, María Del Carmen Costa, Coste, André, Cox, Linda, Cullen, John, Custovic, Adnan, Cvetkovski, Biljana, D’amato, Gennaro, Silva, Jane da, Dahl, Ronald, Dahlen, Sven Erik, Daniilidis, Vasilis, Nahhas, Louei Darjazini, Darsow, Ulf, Blay, Frédéric de, Guia, Eloisa De, Santos, Chato de los, Keenoy, Esteban De Manuel, Vries, Govert De, Deleanu, Diana, Demoly, Pascal, Denburg, Judah, Devillier, Philippe, Didier, Alain, Dimou, Maria, Dinh-Xuan, Anh Tuan, Djukanovic, Ratko, Dokic, Dejan, Domínguez Silva, Margarita Gabriela, Douagui, Habib, Douladiris, Nikolaos, Doulaptsi, Maria, Dray, Gérard, Dubakiene, Ruta, Durham, Stephen, Dykewicz, Mark, Ebo, Didier, Edelbaher, Natalija, Eklund, Patrik, El-Gamal, Yehia, El-Sayed, Zeinab A., El-Sayed, Shereen S., El-Seify, Magda, Emuzyte, Regina, Enecilla, Lourdes, Espinoza, Heidilita, Guillermo, Jesús, Contreras, Espinoza, Farrell, John, Fernandez, Lenora, Wagner, Antje Fink, Fiocchi, Alessandro, Fokkens, Wytske J., Fontaine, Jean François, Forastiere, Francesco, Pèrez, Jose Miguel Fuentes, Gaerlan–resureccion, Emily, Gaga, Mina, Romero, José Luis Gálvez, Gamkrelidze, Amiran, Garcia, Alexis, Cobas, Cecilia Yvonne García, García Cruz, María de la Luz Hortensia, Gayraud, Jacques, Gemicioglu, Bilun, Genova, Sonya, Gereda, José, Wijk, Roy Gerth van, Gomez, Maximiliano, Diaz, Sandra González, Gotua, Maia, Grigoreas, Christos, Grisle, Ineta, Guidacci, Marta, Guldemond, Nick, Gutter, Zdenek, Guzmán, Antonieta, Halloum, Ramsa, Hamelmann, Eckard, Hammadi, Suleiman, Harvey, Richard, Heinrich, Joachim, Hejjaoui, Adnan, Hellquist-Dahl, Birthe, Velázquez, Luiana Hernández, Hew, Mark, Hossny, Elham, Howarth, Peter, Hrubiško, Martin, Villalobos, Yunuen Rocío Huerta, Humbert, Marc, Hyland, Michael, Ibrahim, Moustafa, Ilyina, Natalia, Irani, Carla, Ispayeva, Zhanat, Jares, Edgardo, Jarvis, Deborah, Jassem, Ewa, Jenko, Klemen, Uscanga, Rubén Darío Jiméneracruz, Johnston, Sebastian, Joos, Guy, Jošt, Maja, Julge, Kaja, Jung, Ki Suck, Just, Jocelyne, Kaidashev, Igor, Kalayci, Omer, Kalyoncu, Fuat, Kapsali, Jeni, Kardas, Przemyslaw, Karjalainen, Jussi, Kasala, Carmela A., Katotomichelakis, Michael, Kazi, Bennoor, Keil, Thomas, Keith, Paul, Khaitov, Musa, Khaltaev, Nikolai, Kim, You Young, Kleine-Tebbe, Jorg, Koffi N’Goran, Bernard, Kompoti, Evangelia, Kopač, Peter, Koppelman, Gerard, Jeverica, Anja Koren, Košnik, Mitja, Kostov, Kosta V., Kowalski, Marek L., Kralimarkova, Tanya, Vrščaj, Karmen Kramer, Kraxner, Helga, Kreft, Samo, Kritikos, Vicky, Kudlay, Dmitry, Kull, Inger, Kupczyk, Maciej, Kvedariene, Violeta, Kyriakakou, Marialena, Lalek, Nika, Lane, Stephen, Larenas-Linnemann, Désiree, Lau, Susanne, Lavrut, Jorge, Le, Lan, Lessa, Marcus, Levin, Michael, Li, Jing, Lieberman, Philip, Liotta, Giuseppe, Lipworth, Brian, Liu, Xuandao, Lobo, Rommel, Lodrup Carlsen, Karin C., Lombardi, Carlo, Louis, Renaud, Loukidis, Stelios, Lourenço, Olga, Luna Pech, Jorge A., Madjar, Bojan, Magnan, Antoine, Mahboub, Bassam, Mair, Alpana, Mais, Yassin, van der Zee, Anke Hilse Maitland, Makela, Mika, Makris, Michael, Malling, Hans Jorgen, Mandajieva, Mariana, Manning, Patrick, Manousakis, Manolis, Maragoudakis, Pavlos, Marshall, Gailen, Martins, Pedro, Reza Masjedi, Mohammad, Máspero, Jorge F., Campos, Juan José Matta, Maurer, Marcus, Mavale-Manuel, Sandra, Meço, Cem, Melén, Erik, Melo-Gomes, Elisabete, Meltzer, Eli O., Menditto, Enrica, Menzies-Gow, Andrew, Merk, Hans, Michel, Jean Pierre, Miculinic, Neven, Midão, Luís, Mihaltan, Florin, Mikael, Kuitunen, Mikos, Nikolaos, Milenkovic, Branislava, Mitsias, Dimitrios, Moalla, Bassem, Moda, Giuliana, Martínez, María Dolores Mogica, Mohammad, Yousser, Moin, Mostafa, Molimard, Mathieu, Momas, Isabelle, Monaco, Alessandro, Montefort, Steve, Mora, Dory, Morais-Almeida, Mario, Mösges, Ralph, Mostafa, Badr Eldin, Münter, Lars, Muraro, Antonella, Murray, Ruth, Mustakov, Tihomir, Naclerio, Robert, Nadif, Rachel, Nakonechna, Alla, Namazova-Baranova, Leyla, Navarro-Locsin, Gretchen, Neffen, Hugo, Nekam, Kristof, Neou, Angelos, Nicod, Laurent, Niederberger-Leppin, Verena, Niedoszytko, Marek, Nieto, Antonio, Novellino, Ettore, Nunes, Elizabete, Nyembue, Dieudonné, O’hehir, Robyn, Odjakova, Cvetanka, Ohta, Ken, Okamoto, Yoshitaka, Okubo, Kimi, Oliver, Brian, Onorato, Gabrielle L., Orru, Maria Pia, Ouédraogo, Solange, Ouoba, Kampadilemba, Paggiaro, Pier Luigi, Pagkalos, Aris, Palaniappan, S. P., Pali-Schöll, Isabella, Palkonen, Susanna, Palmer, Stephen, Bunu, Carmen Panaitescu, Panzner, Petr, Papanikolaou, Vasilis, Papi, Alberto, Paralchev, Bojidar, Paraskevopoulos, Giannis, Park, Hae Sim, Passalacqua, Giovanni, Patella, Vincenzo, Pavord, Ian, Pawankar, Ruby, Pedersen, Soren, Peleve, Susete, Pereira, Ana, Pérez, Tamara, Pham-Thi, Nhân, Pigearias, Bernard, Pin, Isabelle, Piskou, Konstantina, Pitsios, Constantinos, Pitsios, Kostas, Plavec, Davor, Poethig, Dagmar, Pohl, Wolfgang, Susic, Antonija Poplas, Popov, Todor A., Portejoie, Fabienne, Potter, Paul, Poulsen, Lars, Prados-Torres, Alexandra, Prarros, Fotis, Price, David, Prokopakis, Emmanuel, Puy, Robert, Rabe, Klaus, Raciborski, Filip, Ramos, Josephine, Recto, Marysia T., Reda, Shereen M., Regateiro, Frederico, Reider, Norbert, Reitsma, Sietze, Repka-Ramirez, Susana, Rimmer, Janet, Yeverino, Daniela Rivero, Rizzo, José Angelo, Robalo-Cordeiro, Carlos, Roberts, Graham, Roche, Nicolas, González, Mónica Rodríguez, Zagal, Eréndira Rodríguez, Rolland, Christine, Roller-Wirns-berger, Regina, Rodriguez, Miguel Roman, Romano, Antonino, Rombaux, Philippe, Romualdez, Joel, Rosado-Pinto, Jose, Rosario, Nelson, Rosenwasser, Lanny, Rottem, Menachem, Rouadi, Philip, Rovina, Nikoleta, Sinur, Irma Rozman, Ruiz, Mauricio, Segura, Lucy Tania Ruiz, Ryan, Dermot, Sagara, Hironori, Sakai, Daiki, Sakurai, Daiju, Saleh, Wafaa, Salimaki, Johanna, Salina, Husain, Samitas, Konstanti Nos, Coronel, María Guadalupe Sánchez, Sanchez-Borges, Mario, Sanchez-Lopez, Jaime, Sarafoleanu, Codrut, Serpa, Faradiba Sarquis, Sastre-Dominguez, Joaquin, Scadding, Glenis, Scheire, Sophie, Schmid-Grendelmeier, Peter, Schuhl, Juan Francisco, Schunemann, Holger, Schvalbová, Maria, Scichilone, Nicola, Sepúlveda, Cecilia, Serrano, Elie, Sheikh, Aziz, Shields, Mike, Shishkov, Vasil, Siafakas, Nikos, Simeonov, Alexander, Simons, Estelle F., Sisul, Juan Carlos, Sitkauskiene, Brigita, Skrindo, Ingelbjorg, Košak, Tanja Soklič, Solé, Dirceu, Sooronbaev, Talant, Soto-Martinez, Manuel, Sova, Milan, Spertini, François, Spranger, Otto, Stamataki, Sofia, Stefanaki, Lina, Stellato, Cristiana, Stelmach, Rafael, Sterk, Peter, Strandberg, Timo, Stute, Petra, Subramaniam, Abirami, Suppli Ulrik, Charlotte, Sutherland, Michael, Sylvestre, Silvia, Syrigou, Aikaterini, Barata, Luis Taborda, Takovska, Nadejda, Tan, Rachel, Tan, Frances, Tan, Vincent, Tang, Ing Ping, Taniguchi, Masami, Tannert, Line, Tattersall, Jessica, Teixeira, Maria Do Ceu, Thijs, Carel, Thomas, Mike, To, Teresa, Todo-Bom, Ana Maria, Togias, Alkis, Tomazic, Peter Valentin, Toppila-Salmi, Sanna, Toskala, Elina, Triggiani, Massimo, Triller, Nadja, Triller, Katja, Tsiligianni, Ioanna, Ulmeanu, Ruxandra, Urbancic, Jure, Pereira, Marilyn Urrutia, Vachova, Martina, Valdés, Felipe, Valenta, Rudolf, Rostan, Marylin Valentin, Valero, Antonio, Vallianatou, Mina, Valovirta, Erkka, Eerd, Michiel Van, Ganse, Eric Van, Hage, Marianne van, Vandenplas, Olivier, Vasankari, Tuula, Vassileva, Dafina, Ventura, Teresa, Vera-Munoz, Cécilia, Vicheva, Dilyana, Vichyanond, Pakit, Vidgren, Petra, Viegi, Giovanni, Vogelmeier, Claus, Hertzen, Leena Von, Vontetsianos, Theodoros, Vourdas, Dimitris, Wagenmann, Martin, Walker, Samantha, Wallace, Dana, Wang, De Yun, Waserman, Susan, Wickman, Magnus, Williams, Sian, Williams, Dennis, Wilson, Nicola, Woo, Kent, Wright, John, Wroczynski, Piotr, Xepapadaki, Paraskevi, Yakovliev, Plamen, Yamaguchi, Masao, Yan, Kwok, Yap, Yoke Yeow, Yawn, Barbara, Yiallouros, Panayiotis, Yoshihara, Shigemi, Young, Ian, Yusuf, Osman B., Zaidi, Asghar, Zaitoun, Fares, Zar, Heather, Zernotti, Mario, Zhang, Luo, Zhong, Nanshan, Zidarn, Mihaela, Zubrinich, Celia, Bousquet, Jean, Anto, Josep M., Iaccarino, Guido, Czarlewski, Wienczyslawa, Haahtela, Tari, Anto, Aram, Akdis, Cezmi, Blain, Hubert, Canonica, G. Walter, Cardona, Victoria, Cruz, Alvaro A., Illario, Maddalena, Ivancevich, Juan Carlos, Jutel, Marek, Klimek, Ludger, Kuna, Piotr, Laune, Daniel, Larenas-linnemann, Désirée, Mullol, Joaquim, Papadopoulos, Nikos G., Pfaar, Oliver, Samolinski, Boleslaw, Valiulis, Arunas, Yorgancioglu, Arzu, Zuberbier, Torsten, Latiff, Amir, Abdullah, Baharudin, Aberer, Werner, Abusada, Nancy, Adcock, Ian, Afani, Alejandro, Agache, Ioana, Aggelidis, Xenofon, Agustin, Jenifer, Akdis, Mübeccel, Al-Ahmad, Mona, Bassam, Abou Al Zahab, Aldrey-Palacios, Oscar, Cuesta, Emilio Alvarez, Alzaabi, Ashraf, Amad, Salma, Ambrocio, Gene, Annesi-Maesano, Isabella, Ansotegui, Ignacio, Anto, Josep, Arshad, Hasan, Artesani, Maria Cristina, Asayag, Estrella, Avolio, Francesca, Azhari, Khuzama, Baiardini, Ilaria, Bajrović, Nissera, Bakakos, Petros, Mongono, Sergio Bakeyala, Balotro-Torres, Christine, Barba, Sergio, Barbara, Cristina, Barbosa, Elsa, Barreto, Bruno, Bartra, Joan, Bateman, Eric D., Battur, Lkhagvaa, Bedbrook, Anna, Barajas, Martín Bedolla, Beghé, Bianca, Bel, Elizabeth, Kheder, Ali Ben, Benson, Mikael, Berghea, Camelia, Bergmann, Karl Christian, Bernstein, David, Bewick, Mike, Bialek, Slawomir, Białoszewski, Artur, Bieber, Thomas, Billo, Nils, Bilo, Maria Beatrice, Bindslev-Jensen, Carsten, Bjermer, Leif, Marciniak, Malgorzata Bochenska, Bond, Christine, Boner, Attilio, Bonini, Matteo, Bonini, Sergio, Bosnic-Anticevich, Sinthia, Bosse, Isabelle, Botskariova, Sofia, Bouchard, Jacques, Boulet, Louis Philippe, Bourret, Rodolphe, Bousquet, Philippe, Braido, Fulvio, Briggs, Andrew, Brightling, Christopher, Brozek, Jan, Buhl, Roland, Bumbacea, Roxana, Cabañas, María Teresa Burguete, Bush, Andrew, Busse, William W., Buters, Jeroen, Caballero-Fonseca, Fernan, Calderon, Moïses A., Calvo, Mario, Camargos, Paulo, Camuzat, Thierry, Cano, Antonio, Capriles-Hulett, Arnaldo, Caraballo, Luis, Cardona, Vicky, Carlsen, Kai Hakon, Caro, Jorge, Carreon-Asun-cion, Fredelita, Carriazo, Ana Maria, Casale, Thomas, Castor, Mary Ann, Castro, Elizabeth, Cecchi, Lorenzo, Sarabia, Alfonso Cepeda, Chandrasekharan, Ramanathan, Chang, Yoon Suk, Chato-Andeza, Victoria, Chatzi, Lida, Chatzidaki, Christina, Chavannes, Niels H., Chen, Yuzhi, Cheng, Lei, Chivato, Tomas, Chkhartishvili, Ekaterine, Christoff, George, Chrystyn, Henry, Chu, Derek K., Chua, Antonio, Chuchalin, Alexander, Chung, Kian Fan, Cicerán, Alberto, Cingi, Cemal, Ciprandi, Giorgio, Cirule, Ieva, Coelho, Ana Carla, Constantinidis, Jannis, de Sousa, Jaime Correia, Costa, Elisio, Costa, David, Domínguez, María Del Carmen Costa, Coste, André, Cox, Linda, Cullen, John, Custovic, Adnan, Cvetkovski, Biljana, D’amato, Gennaro, Silva, Jane da, Dahl, Ronald, Dahlen, Sven Erik, Daniilidis, Vasilis, Nahhas, Louei Darjazini, Darsow, Ulf, Blay, Frédéric de, Guia, Eloisa De, Santos, Chato de los, Keenoy, Esteban De Manuel, Vries, Govert De, Deleanu, Diana, Demoly, Pascal, Denburg, Judah, Devillier, Philippe, Didier, Alain, Dimou, Maria, Dinh-Xuan, Anh Tuan, Djukanovic, Ratko, Dokic, Dejan, Domínguez Silva, Margarita Gabriela, Douagui, Habib, Douladiris, Nikolaos, Doulaptsi, Maria, Dray, Gérard, Dubakiene, Ruta, Durham, Stephen, Dykewicz, Mark, Ebo, Didier, Edelbaher, Natalija, Eklund, Patrik, El-Gamal, Yehia, El-Sayed, Zeinab A., El-Sayed, Shereen S., El-Seify, Magda, Emuzyte, Regina, Enecilla, Lourdes, Espinoza, Heidilita, Guillermo, Jesús, Contreras, Espinoza, Farrell, John, Fernandez, Lenora, Wagner, Antje Fink, Fiocchi, Alessandro, Fokkens, Wytske J., Fontaine, Jean François, Forastiere, Francesco, Pèrez, Jose Miguel Fuentes, Gaerlan–resureccion, Emily, Gaga, Mina, Romero, José Luis Gálvez, Gamkrelidze, Amiran, Garcia, Alexis, Cobas, Cecilia Yvonne García, García Cruz, María de la Luz Hortensia, Gayraud, Jacques, Gemicioglu, Bilun, Genova, Sonya, Gereda, José, Wijk, Roy Gerth van, Gomez, Maximiliano, Diaz, Sandra González, Gotua, Maia, Grigoreas, Christos, Grisle, Ineta, Guidacci, Marta, Guldemond, Nick, Gutter, Zdenek, Guzmán, Antonieta, Halloum, Ramsa, Hamelmann, Eckard, Hammadi, Suleiman, Harvey, Richard, Heinrich, Joachim, Hejjaoui, Adnan, Hellquist-Dahl, Birthe, Velázquez, Luiana Hernández, Hew, Mark, Hossny, Elham, Howarth, Peter, Hrubiško, Martin, Villalobos, Yunuen Rocío Huerta, Humbert, Marc, Hyland, Michael, Ibrahim, Moustafa, Ilyina, Natalia, Irani, Carla, Ispayeva, Zhanat, Jares, Edgardo, Jarvis, Deborah, Jassem, Ewa, Jenko, Klemen, Uscanga, Rubén Darío Jiméneracruz, Johnston, Sebastian, Joos, Guy, Jošt, Maja, Julge, Kaja, Jung, Ki Suck, Just, Jocelyne, Kaidashev, Igor, Kalayci, Omer, Kalyoncu, Fuat, Kapsali, Jeni, Kardas, Przemyslaw, Karjalainen, Jussi, Kasala, Carmela A., Katotomichelakis, Michael, Kazi, Bennoor, Keil, Thomas, Keith, Paul, Khaitov, Musa, Khaltaev, Nikolai, Kim, You Young, Kleine-Tebbe, Jorg, Koffi N’Goran, Bernard, Kompoti, Evangelia, Kopač, Peter, Koppelman, Gerard, Jeverica, Anja Koren, Košnik, Mitja, Kostov, Kosta V., Kowalski, Marek L., Kralimarkova, Tanya, Vrščaj, Karmen Kramer, Kraxner, Helga, Kreft, Samo, Kritikos, Vicky, Kudlay, Dmitry, Kull, Inger, Kupczyk, Maciej, Kvedariene, Violeta, Kyriakakou, Marialena, Lalek, Nika, Lane, Stephen, Larenas-Linnemann, Désiree, Lau, Susanne, Lavrut, Jorge, Le, Lan, Lessa, Marcus, Levin, Michael, Li, Jing, Lieberman, Philip, Liotta, Giuseppe, Lipworth, Brian, Liu, Xuandao, Lobo, Rommel, Lodrup Carlsen, Karin C., Lombardi, Carlo, Louis, Renaud, Loukidis, Stelios, Lourenço, Olga, Luna Pech, Jorge A., Madjar, Bojan, Magnan, Antoine, Mahboub, Bassam, Mair, Alpana, Mais, Yassin, van der Zee, Anke Hilse Maitland, Makela, Mika, Makris, Michael, Malling, Hans Jorgen, Mandajieva, Mariana, Manning, Patrick, Manousakis, Manolis, Maragoudakis, Pavlos, Marshall, Gailen, Martins, Pedro, Reza Masjedi, Mohammad, Máspero, Jorge F., Campos, Juan José Matta, Maurer, Marcus, Mavale-Manuel, Sandra, Meço, Cem, Melén, Erik, Melo-Gomes, Elisabete, Meltzer, Eli O., Menditto, Enrica, Menzies-Gow, Andrew, Merk, Hans, Michel, Jean Pierre, Miculinic, Neven, Midão, Luís, Mihaltan, Florin, Mikael, Kuitunen, Mikos, Nikolaos, Milenkovic, Branislava, Mitsias, Dimitrios, Moalla, Bassem, Moda, Giuliana, Martínez, María Dolores Mogica, Mohammad, Yousser, Moin, Mostafa, Molimard, Mathieu, Momas, Isabelle, Monaco, Alessandro, Montefort, Steve, Mora, Dory, Morais-Almeida, Mario, Mösges, Ralph, Mostafa, Badr Eldin, Münter, Lars, Muraro, Antonella, Murray, Ruth, Mustakov, Tihomir, Naclerio, Robert, Nadif, Rachel, Nakonechna, Alla, Namazova-Baranova, Leyla, Navarro-Locsin, Gretchen, Neffen, Hugo, Nekam, Kristof, Neou, Angelos, Nicod, Laurent, Niederberger-Leppin, Verena, Niedoszytko, Marek, Nieto, Antonio, Novellino, Ettore, Nunes, Elizabete, Nyembue, Dieudonné, O’hehir, Robyn, Odjakova, Cvetanka, Ohta, Ken, Okamoto, Yoshitaka, Okubo, Kimi, Oliver, Brian, Onorato, Gabrielle L., Orru, Maria Pia, Ouédraogo, Solange, Ouoba, Kampadilemba, Paggiaro, Pier Luigi, Pagkalos, Aris, Palaniappan, S. 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Abstract

Reported COVID-19 deaths in Germany are relatively low as compared to many European countries. Among the several explanations proposed, an early and large testing of the population was put forward. Most current debates on COVID-19 focus on the differences among countries, but little attention has been given to regional differences and diet. The low-death rate European countries (e.g. Austria, Baltic States, Czech Republic, Finland, Norway, Poland, Slovakia) have used different quarantine and/or confinement times and methods and none have performed as many early tests as Germany. Among other factors that may be significant are the dietary habits. It seems that some foods largely used in these countries may reduce angiotensin-converting enzyme activity or are anti-oxidants. Among the many possible areas of research, it might be important to understand diet and angiotensin-converting enzyme-2 (ACE2) levels in populations with different COVID-19 death rates since dietary interventions may be of great benefit.

Published
2020

95. Asthma control in Europe: A real-world evaluation based on an international population-based study

Author

Cazzoletti, Lucia, Marcon, Alessandro, Janson, Christer, Corsico, Angelo, Jarvis, Deborah, Pin, Isabelle, Accordini, Simone, Almar, Enrique, Bugiani, Massimiliano, Carolei, Adriana, Cerveri, Isa, Duran-Tauleria, Enric, Gislason, David, Gulsvik, Amund, Jõgi, Rain, Marinoni, Alessandra, Martínez-Moratalla, Jesús, Vermeire, Paul, and de Marco, Roberto

Published
2007
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99. Ultraviolet radiation as a predictor of sex hormone levels in postmenopausal women: A European multi-center study (ECRHS)

Author

Triebner, Kai, primary, Bifulco, Ersilia, additional, Barrera-Gómez, Jose, additional, Basagaña, Xavier, additional, Benediktsdóttir, Bryndís, additional, Forsberg, Bertil, additional, Franklin, Karl A., additional, Garcia-Larsen, Vanessa, additional, Leynaert, Bénédicte, additional, Lindberg, Eva, additional, Martínez-Moratalla, Jesús, additional, Muniozguren-Agirre, Nerea, additional, Pin, Isabelle, additional, Raherison, Chantal, additional, Pereira-Vega, Antonio, additional, Schlünssen, Vivi, additional, Valentin, Antonia, additional, Hustad, Steinar, additional, Real, Francisco Gómez, additional, and Dadvand, Payam, additional

Published
2021
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100. Cumulative Occupational Exposures and Lung-Function Decline in Two Large General-Population Cohorts

Author

Lytras, Theodore, primary, Beckmeyer-Borowko, Anna, additional, Kogevinas, Manolis, additional, Kromhout, Hans, additional, Carsin, Anne-Elie, additional, Antó, Josep Maria, additional, Bentouhami, Hayat, additional, Weyler, Joost, additional, Heinrich, Joachim, additional, Nowak, Dennis, additional, Urrutia, Isabel, additional, Martínez-Moratalla, Jesús, additional, Gullón, José Antonio, additional, Pereira Vega, Antonio, additional, Raherison Semjen, Chantal, additional, Pin, Isabelle, additional, Demoly, Pascal, additional, Leynaert, Bénédicte, additional, Villani, Simona, additional, Gislason, Thorarinn, additional, Svanes, Øistein, additional, Holm, Mathias, additional, Forsberg, Bertil, additional, Norbäck, Dan, additional, Mehta, Amar J., additional, Keidel, Dirk, additional, Vernez, David, additional, Benke, Geza, additional, Jõgi, Rain, additional, Torén, Kjell, additional, Sigsgaard, Torben, additional, Schlünssen, Vivi, additional, Olivieri, Mario, additional, Blanc, Paul D., additional, Watkins, John, additional, Bono, Roberto, additional, Squillacioti, Giulia, additional, Buist, A. Sonia, additional, Vermeulen, Roel, additional, Jarvis, Deborah, additional, Probst-Hensch, Nicole, additional, and Zock, Jan-Paul, additional

Published
2021
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