Search

Your search keyword '"Pichardo S"' showing total 342 results
Start Over Author "Pichardo S"
342 results on '"Pichardo S"'

51. Fingerprinting (Py-GC/MS) of a bio-film active food package with Origanum vulgare L. essential oil.

Author

European Commission, Junta de Andalucía, Llana Ruiz-Cabello, M., Pichardo, S., Jiménez Morillo, N. T., Bermúdez Saldaña, José María, Aucejo, S., González-Vila, Francisco Javier, Cameán Fernández, A. M., González-Pérez, José Antonio, European Commission, Junta de Andalucía, Llana Ruiz-Cabello, M., Pichardo, S., Jiménez Morillo, N. T., Bermúdez Saldaña, José María, Aucejo, S., González-Vila, Francisco Javier, Cameán Fernández, A. M., and González-Pérez, José Antonio

Abstract

The use of biobased packaging materials are becoming an alternative to polymers produced from non-renewable resources. Moreover, increasing interest in the use of active additives from natural sources has been observed in consumers and industry. Oregano essential oil (EO) is being included in new materials due to its bioactive properties. However, due to EOs high volatility, aspects like ageing and conditions of films preparation may cause losses of active agent. In this work, analytical pyrolysis (Py–GC/MS) was used to fingerprint a bioactive polylactic acid (PLA) with polybutylene succinate (PBS) (95:5) film extruded with variable quantities of oregano essential oil. Bio-plastic pyrolysis detected both, lactide enantiomers and monomer units from the PLA and specific molecular markers from the PBS fraction. Oregano EO pyrolysis released aromatics and terpenes with cymene, terpinene and thymol/carvacrol peaks identified as diagnostic peaks. Linear correlation coefficients < 0.950R2 (p < 0.001) were found between the chromatographic area of these diagnostic peaks and the amount of oregano EO included in the bioplastic matrix. Our results indicate that Py–GC/MS is a valuable tool providing not only a precise fingerprinting but also precise information about composition, quality and additives in active packages made with biogenic polymers

Published
2015

61. Influence of a subchronical exposure to a modified clay and its migration extract in the spleen of Wistar rats

Author

Ministerio de Ciencia e Innovación (AGL2010-21210) y Junta de Andalucía (AGR5969), Maisanaba, S., Pichardo, S., Jordá, M., Aucejo, S., Cameán, A. M., Jos, A., Ministerio de Ciencia e Innovación (AGL2010-21210) y Junta de Andalucía (AGR5969), Maisanaba, S., Pichardo, S., Jordá, M., Aucejo, S., Cameán, A. M., and Jos, A.

Abstract

The technological advantages of the incorporation of modified clays into polymers for food packaging are well known. However, there are still many uncertainties about the safety of these materials. The Technological Institute of Packaging, Transport and Logistic has developed Clay1, a modified clay with a quaternary ammonium salt. This organoclay is incorporated into the polymer (polylactic acid), giving a nanocomposite material and reinforcing the bulk material. The aim of this study is to evaluate the activity of several oxidative stress biomarkers in the spleen of rats exposed for 90 days to Clay1 (40 mg/kg/day) and its migration extract obtained from the resultant nanocomposite material. The parameters evaluated were lipid peroxidation and superoxide dismutase and catalase activities. Moreover, the characteristic metallic components of the organoclay (Al, Ca, Fe, Mg, Si) were also analyzed to test the possible accumulation. In this study, three groups of Wistar rats (n=10) were used: control (standard food + water), Clay1 (food with Clay1+water) and Clay1 extract (standard food+ Clay1 extract as water). After the exposure the spleen was removed. In general, no significant differences were observed in any of the parameters evaluated compared to the control group, therefore Clay1 showed a good toxicologic profile regarding the biomarkers assayed for its use in the food industry., Las ventajas tecnológicas de la incorporación de arcillas modificadas en polímeros para el envasado de alimentos son bien conocidas, pero aún quedan muchas incertidumbres sobre la seguridad de estos materiales. El Instituto Tecnológico del Embalaje, Transporte y Logística ha desarrollado una arcilla, Clay1, modificando una montmorillonita con una sal de amonio cuaternario. Esta organoarcilla, incorporada al polímero (ácido poliláctico), da lugar a un material nanocompuesto, reforzándose así el material de partida. El principal objetivo de este estudio es evaluar la actividad de biomarcadores de estrés oxidativo en bazo de ratas expuestas durante 90 días a Clay1 (40 mg/kg/día) y al extracto de migración obtenido a partir del material nanocompuesto resultante. Los parámetros evaluados fueron la peroxidación lipídica y las actividades enzimáticas superóxido dismutasa y catalasa. Además, se realizó un análisis del contenido en bazo de los metales más característicos que componen la organoarcilla (Al, Ca, Fe, Mg, Si) para comprobar su posible acumulación. En dicho estudio se trabajó con tres grupos de ratas Wistar (n=10): control (comida estándar + agua como bebida), Clay1 (comida estándar mezclada con 40mg/kg/día de arcilla + agua) y extracto de Clay1 (comida estándar + extracto como bebida). Tras el tiempo de exposición los animales se sacrificaron y se extrajo el bazo. De forma general, no se observaron diferencias significativas en ninguno de los parámetros evaluados con respecto al grupo control, por lo que Clay1 muestra un buen perfil toxicológico respecto a los biomarcadores ensayados con vistas a su uso en la industria alimentaria.

Published
2014

62. DERIVADOS ORGANOSULFURADOS COMO POTENCIALES ADITIVOS EN ALIMENTACIÓN ANIMAL: UNA OPORTUNIDAD PARA LA EVALUACIÓN DE RIESGOS.

Author

Pichardo, S., Cascajosa-Lira, A., Prieto, A. I., Medrano-Padial, C., Baños, A., Guillamón, E., Jos, A., and Cameán, A. M.

Subjects
ORGANOSULFUR compounds, FOOD of animal origin, FOOD toxicology, ANIMAL feeds, ORANGE juice, CYANOBACTERIAL toxins, GARLIC
Abstract

Copyright of Revista de Toxicología is the property of Asociacion Espanola de Toxicologia and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2022

63. BIOTRANSFORMACIÓN IN VITRO DEL PROPILPROPANO-TIOSULFONATO (PTSO): IDENTIFICACIÓN Y CARACTERIZACIÓN DE METABOLITOS.

Author

Cascajosa-Lira, A., Medrano-Padial, C., Pichardo, S., Baños, A., Guillamón, E., Jos, A., and Cameán, A. M.

Subjects
CELL lines, CELL survival, BISPHENOLS, BIOCONVERSION, SCHOOL children
Abstract

Copyright of Revista de Toxicología is the property of Asociacion Espanola de Toxicologia and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2022

64. Papel de las tiazidas en la profilaxis de la litiasis cálcica recidivante

Author

Fernández-Rodríguez, A., Arrabal-Martín, M., García-Ruiz, Mª J., Arrabal-Polo, M.A., Pichardo-Pichardo, S., and Zuluaga-Gómez, A.

Subjects
Prevención, Litiasis renal, Prevention, Renal lithiasis, Recidiva
Abstract

Objetivo: Demostrar la eficacia prolongada de las tiazidas en la profilaxis y tratamiento de las recidivas en pacientes con litiasis cálcica de oxalato y fosfato cálcico. Métodos: Se realiza un estudio prospectivo aleatorizado, con un seguimiento de tres años, en 150 pacientes diagnosticados de litiasis cálcica recidivante. Los pacientes se distribuyen en tres grupos: A) 50 casos sometidos a observación sin tratamiento, B) 50 casos tratados con 50 mg/día de hidroclorotiazida y C) 50 casos tratados con 50 mg de hidroclorotiazida y 20 mlEq de citrato potásico/día. En cada grupo se realiza estudio renal con técnicas de imagen, y estudio metabólico urinario basal, 12, 24 y 36 meses. Resultados: En los pacientes tratados con tiazidas (Grupo B y C) se obtiene una reducción significativa de recidiva litiásica en relación con el grupo control (Grupo A). La alteración más frecuente encontrada en el estudio metabólico fue hipercalciuria, 52% de los casos; el 16% presentan patrón litógeno mixto. El número de recidivas y necesidad de nuevas sesiones de litotricia extracorpórea en los pacientes con hipercalciuria tratados con tiazidas disminuye significativamente con respecto al Grupo A (p=0.003) Conclusiones: Se observa una relación significativa entre patrón litógeno y recidiva litiásica. Las tiazidas nos ayudan a controlar los factores litogénicos y las recidivas en pacientes con litiasis cálcica. Este efecto es prolongado y significativo en pacientes con hipercalciuria. Objective: To show the prolonged efficacy of thiazides in the prophylaxis and treatment of recurrences in patients with calcium oxalate and phosphate lithiasis. Methods: A randomised prospective study is conducted, with a three-year follow-up, in 150 patients diagnosed with recurrent calcium lithiasis. The patients are divided into three groups: A) 50 cases subject to observation with no treatment, B) 50 cases treated with 50 mg/day of hydrochlorothiazide, and C) 50 cases treated with 50 mg of hydrochlorothiazide and 20 mlEq of potassium citrate/day. Each group is subject to a renal study with imaging techniques and a urinary metabolic study at baseline, 12, 24 and 36 months. Results: The patients treated with thiazides (Groups B and C) obtain a significant reduction in lithiasis recurrence compared with the control group (Group A). The most common abnormality found in the metabolic study was hypercalciuria, 52% of cases; 16% present a mixed lithogenic pattern. The number of recurrences and need for new sessions of extracorporeal lithotripsy in patients with hypercalciuria treated with thiazides is significantly smaller than in Group A (p=0.003. Conclusions: We observe a significant relation between lithogenic pattern and lithiasis recurrence. Thiazides help us to control lithogenic factors and recurrences in patients with calcium lithiasis. This effect is prolonged and significant in patients with hypercalciuria.

Published
2006

65. New advances in active packaging incorporated with essential oils or their main components for food preservation.

Author

Maisanaba, S., Llana-Ruiz-Cabello, M., Gutiérrez-Praena, D., Pichardo, S., Puerto, M., Prieto, A. I., Jos, A., and Cameán, A. M.

Subjects
FOOD industry, ESSENTIAL oils, FOOD preservation, ACTIVE food packaging, ANTIMICROBIAL preservatives
Abstract

The food industry is developing new packaging systems (active packaging) through the incorporation of essential oils or their main compounds into the films. This could confer them the antimicrobial and/or antioxidant properties already extensively described for these substances, improving the shelf life of perishable food products. However, a safe range of concentrations for their use in active food packaging should be established to reach the market proposals and avoid risks for consumers. The present work reviews the scientific literature concerning these two properties together with the toxic effects induced by these substances on human cell lines. [ABSTRACT FROM AUTHOR]

Published
2017
Full Text
View/download PDF

68. Estilbenos como una alternativa sostenible al anhídrido sulfuroso en vinos

Author

Gutiérrez-Escobar Rocío, Puertas Belén, Jesús Jiménez Hierro María, José Aliaño-González María, Medrano-Padial Concepción, Pichardo Silvia, Richard Tristan, and Cantos-Villar Emma

Subjects
Microbiology, QR1-502, Physiology, QP1-981, Zoology, QL1-991
Abstract

Resumen El anhídrido sulfuroso (SO2) es el conservante más empleado en la industria agroalimentaria y enológica por sus propiedades antioxidantes y antimicrobianas. Sin embargo, también es un alérgeno que puede provocar problemas de salud en personas sensibles a él. Por otra parte, la madera de poda procedente de los viñedos es uno de los principales subproductos de la industria vitivinícola, con un volumen estimado entre 2 y 4 toneladas por hectárea y año. Este subproducto vitícola contiene polifenoles, entre otros estilbenos bioactivos con propiedades saludables. En el presente trabajo se ha elaborado y caracterizado un extracto puro de estilbenos obtenido a partir de madera de poda de la vid, para utilizarlo como alternativa sostenible al SO2 en la elaboración de vinos blancos y rosados. Se evaluó el impacto del extracto sobre la calidad de los vinos (parámetros enológicos, color, compuestos fenólicos y perfil sensorial) tanto en el embotellado y a los doce meses del embotellado. En paralelo se evaluó la posible toxicidad del extracto. Los resultados obtenidos concluyen que el extracto puro de estilbenos, obtenido a partir de madera de poda de la vid, puede proponerse como alternativa natural y sostenible al empleo de SO2 en la vinificación de vinos blancos y rosados. Además, el extracto no mostró toxicidad ni in vitro ni in vivo.

Published
2023
Full Text
View/download PDF

69. Toxicology at the University of Seville

Author

Moreno, I. M., Jos, A., Pichardo, S., Pichardo, A., Puerto, M., Cameán, A. M., Moreno, I. M., Jos, A., Pichardo, S., Pichardo, A., Puerto, M., and Cameán, A. M.

Abstract

The teaching in the Area of Toxicology at the University of Seville is currently being developed in two degrees, Pharmacy and Biochemistry. In the present curriculum, the teaching load of the area is given by the subjects of Toxicology (compulsory subject), and Food Toxicology (elective subject) in the Bachelor of Pharmacy; and Molecular Toxicology (elective subject) in the Bachelor of Biochemistry. Once approved by the National Agency for Quality Assessment and Accreditation (ANECA) both titles, this teaching is not only maintained but even increased through participation in the teaching of two newly created multidisciplinary subjects in the degree of Pharmacy., La docencia del Área de Toxicología en la Universidad de Sevilla se desarrolla en la actualidad en dos titulaciones, Farmacia y Bioquímica. En los planes de estudios actuales la carga lectiva del Área viene dada por las asignaturas de Toxicología (asignatura troncal), y Toxicología Alimentaria (asignatura optativa) en la Licenciatura de Farmacia, y de Toxicología Molecular (asignatura optativa) en la Licenciatura de Bioquímica. Una vez aprobados por la Agencia Nacional de la Evaluación de la Calidad y Acreditación (ANECA) ambos títulos de Grado, la docencia no sólo se mantiene sino que se amplía gracias a la participación en la impartición de dos asignaturas pluridisciplinares de nueva creación en el Grado deFarmacia.

Published
2010

80. Development of PLA films containing oregano essential oil (Origanum vulgare L. virens) intended for use in food packaging.

Author

Llana-Ruiz-Cabello, M., Pichardo, S., Bermúdez, J.M., Baños, A., Núñez, C., Guillamón, E., Aucejo, S., and Cameán, A.M.

Subjects
*OREGANO, *FOOD packaging, *ESSENTIAL oils, *POLYLACTIC acid, *ADDITIVES, *MATRICES (Mathematics)
Abstract

Consumers' concerns about the environment and health have led to the development of new food packaging materials avoiding petroleum-based matrices and synthetic additives. The present study has developed polylactic acid (PLA) films containing different concentrations of essential oil from Origanum vulgare L. virens (OEO). The effectiveness of this new active packaging was checked for use in ready-to-eat salads. A plasticising effect was observed when OEO was incorporated in PLA films. The rest of the mechanical and physical properties of developed films did not show much change when OEO was included in the film. An antioxidant effect was recorded only for films containing the highest percentages of the active agent (5% and 10%). In addition, films exhibited in vitro antibacterial activity against Staphylococcus aureus, Yersinia enterocolitica, Listeria monocytogenes, Enterococcus faecalis and Staphylococcus carnosus. Moreover, in ready-to-eat salads, antimicrobial activity was only observed against yeast and moulds, where 5% and 10% of OEO was the most effective. [ABSTRACT FROM AUTHOR]

Published
2016
Full Text
View/download PDF

94. IMPLEMENTACIÓN DE HERRAMIENTAS VIRTUALES DE EVALUACIÓN EN PRÁCTICAS DE TOXICOLOGÍA.

Author

Guzmán-Guillén, R., Cascajosa-Lira, A., Prieto, A., Puerto, M., Pichardo, S., Díez-Quijada, L., Plata-Calzado, C., and Cebadero-Domínguez, O.

Subjects
ATTITUDES toward the environment, VITIS vinifera, STUDENT attitudes, WEB-based user interfaces, ANIMAL experimentation, FUNGAL metabolites
Abstract

Copyright of Revista de Toxicología is the property of Asociacion Espanola de Toxicologia and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2022

95. P-SA/09- ESTILBENOS COMO ALTERNATIVA AL SULFUROSO: EVALUACIÓN DE LA FORMACIÓN DE ESPECIES REACTIVAS DE OXÍGENO EN CÉLULAS CACO-2 EXPUESTAS A UN EXTRACTO RICO EN ESTILBENOS Y SUS COMPONENTES MAYORITARIOS.

Author

Medrano-Padial, C., Merchán-Gragero, M. M., Puerto, M., Richard, T., Cantos-Villar, E., and Pichardo, S.

Abstract

Copyright of Revista de Toxicología is the property of Asociacion Espanola de Toxicologia and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2019

96. P-ET/07- ORGANIZACIÓN DE LAS III JORNADAS DE TOXICOLOGÍA Y SOCIEDAD: DROGAS DE ABUSO Y TOXICOLOGÍA MOLECULAR (FORO Y OLIMPIADA DE TOXICOLOGÍA).

Author

Guzmán-Guillén, R., Hinojosa, M. G., Medrano-Padial, C., Díez-Quijada, L., Catunescu, G., Merchán, M. M., Llana-Ruíz-Cabello, M., Puerto, M., Prieto, A. I., Pichardo, S., Moreno, I. M., Jos, A., Cameán, A. M., and Gutiérrez-Praena, D.

Abstract

Copyright of Revista de Toxicología is the property of Asociacion Espanola de Toxicologia and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2019

97. P-SA/11- CITOTOXICIDAD DE UN EXTRACTO DE ESTILBENOS, SUS COMPONENTES MAYORITARIOS Y SU MEZCLA EN LA LÍNEA CELULAR CACO-2.

Author

Medrano-Padial, C., Merchán-Gragero, M. M., Puerto, M., Richard, T., Cantos-Villar, E., and Pichardo, S.

Abstract

Copyright of Revista de Toxicología is the property of Asociacion Espanola de Toxicologia and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2019

98. P-SA/10- EVALUACIÓN DE LA MUTAGENICIDAD DE UN EXTRACTO DE ESTILBENOS MEDIANTE EL TEST DE AMES.

Author

Medrano-Padial, C., Merchán-Gragero, M. M., Prieto, A. I., Cameán, A. M., Richard, T., Cantos-Villar, E., and Pichardo, S.

Abstract

Copyright of Revista de Toxicología is the property of Asociacion Espanola de Toxicologia and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2019

99. P-SA/08- EVALUACIÓN GENOTÓXICA DE UN EXTRACTO NATURAL RICO EN ESTILBENOS MEDIANTE EL ENSAYO DE MICRONÚCLEOS.

Author

Medrano-Padial, C., Prieto, A. I., Puerto, M., Richard, T., Cantos-Villar, E., Cameán, A. M., and Pichardo, S.

Abstract

Copyright of Revista de Toxicología is the property of Asociacion Espanola de Toxicologia and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2019

100. P-SA/05- ESTUDIO DEL PAPEL ANTIOXIDANTE DE UN EXTRACTO RICO EN ESTILBENOS, RESVERATROL, ε - VINIFERINA Y SU MEZCLA MEDIANTE LA MEDIDA DE LOS NIVELES DE GLUTATION REDUCIDO EN CÉLULAS CACO-2.

Author

Medrano-Padial, C., Merchán-Gragero, M. M., Puerto, M., Richard, T., Cantos-Villar, E., and Pichardo, S.

Abstract

Copyright of Revista de Toxicología is the property of Asociacion Espanola de Toxicologia and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2019

Catalog

Books, media, physical & digital resources
See catalog results