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Stress at the work place was declared by the World Health Organization as a worldwide epidemic. The stress caused by work appears when the balance between one’s own possibilities and the environment demands is disturbed, which leads to a poor mental state. The fact is that the majority of dentists find they are under constant stress, which is caused by the nature of dental work. Literature describes dentistry as an extremely stressful profession. The main stressors include the tendency toward technical perfection, the causation of pain in patients, the lack of patient cooperation during dental treatment, the failure to maintain the given appointments. Adequate education and preparation, even during dental studies, non-neglect of symptoms and difficulties at the work place, adequate and timely response to the identification of the cause and its elimination or balancing, have a key role in solving this great problem in modern dentistry.

Introduction/Objective. Essential Science Indicators (ESI) Highly Cited Papers (HCPs) refer to the most influential scientific articles and breakthrough research within a research field in the past decade. This study aimed to identify the characteristics of ESI HCPs in the subject category Dentistry, Oral Surgery and Medicine, to recognize authors, institutions and countries of origin, and determine research trends that attracted the most scientific interest in dentistry. Methods. A descriptive analysis of bibliographic data, network extraction and visualization were completed. Furthermore, analyzed ESI HCPs were classified according to a field of interest, main research domain, type of study, and level of evidence. Results. The set of 185 dental HCPs was published in 42 journals from 2010 to 2020, with an average number of 211.7 citations per paper. Nearly half of HCPs were issued by the Journal of Dental Research, Dental Materials, and Journal of Clinical Periodontology. There were 765 authors affiliated with 351 institutions from 42 countries. The most productive institutions were the University of Hong Kong, the University of Michigan, and the University of Bern. The United States of America contributed with the highest number of publications, followed by China, and the United Kingdom. Dental materials, dental implantology, periodontology, and oral and maxillofacial surgery represented areas of significant interest within this subject category. The highest proportion of HCPs were narrative and systematic reviews, expert opinions, consensus reports, and in vitro оr lab studies. Conclusion. Results obtained from this study can provide valuable information for researchers to better identify present and future hotspots in dental research.

Synthetic hydroxyapatite (Ca10(PO4)6(OH)2, HAp) is very similar to the inorganic part of the bones and teeth of mammals. It is a well-known biomaterial with good biocompatibility, osteoconductivity and bioactivity. Nifuroxazide (C12H9N3O5, NFX) is a broad-spectrum antibacterial drug and poorly soluble in water. In order to increase the solubility of NFX, nano-sized HAp powder and raw NFX drug were mixed giving, as a result, a HAp/NFX conjugate. Characterization of the raw materials and the obtained conjugate confirmed the integration of NFX on the HAp surface. An in vitro study of drug release in simulated stomach acid and intestinal fluid showed a much faster release of NFX from HAp surface than those of the raw drug. The HAp/NFX conjugate showed excellent inhibitory effects against Gram-positive bacterium Staphylococcus aureus, Gram-negative bacterium Escherichia coli and yeast Candida albicans, proving the nano-sized HAp powder as a promising drug carrier.

In 1973, the Chilean army led by General Augusto Pinochet, with the support of Chilean right-wing formations and the United States, overthrew the world's first democratically elected leftist regime - the regime of Salvador Allende. In addition to strong political reforms, embodied in the banning of the Communist Party of Chile and the persecution of left-wing dissidents, Pinochet immediately began intensive economic reforms inspired by the neoliberal, the so-called shock therapy that originated at the famous Chicago School. The reforms were aimed at dissolving Chile's short-lived socialist legacy, which was reflected in the country's nationalization of land and natural resources, the improvement of workers and trade unions rights, and an accessible health, education and social system. Nationalized goods have been returned to their owners or redistributed to individuals in general, union work has been limited, and the principles of doing business in the market have been extremely liberalized in order to attract as many foreign investors as possible, usually powerful multinational corporations. An important segment of the reforms was the stabilization of the inflation rate. In this paper, we will follow two waves of reforms - from 1973 to 1990 (when Pinochet was overthrown) and from 1990 to 2019, when there were strong riots on the streets of Chile due to the announced increase in subway transportation prices, and in fact, driven by the overall dissatisfaction of citizens with the end effects of reforms - unequal income redistribution, austerity measures, a large number of extremely poor and expensive public services in the fields of education and health. Despite that, we will also point out the positive effects of the reforms - long-term positive macroeconomic trends, high average salary for Latin American conditions, significant inflow of foreign investments, etc. In this paper, we will use the method of analysis and the case study method.

Balanced regional development is one of the cornerstones of sustainable economic growth and development of any country. During the years that followed the democratic changes in 2000, the Republic of Serbia found itself in sinister transitional processes. One of the key transitional issues was the policy of balanced regional development. Therefore, the aim of this research is to examine the mechanisms and instruments of balanced regional development in the Republic of Serbia in the period from 2000 to 2018 as well as the effects of their implementation in practice. The results of the research indicate the presence of unbalanced regional development throughout the observed period. Although in a normative sense a framework for the implementation of comprehensive and developmental reforms in this area has been set, the results are missing in practice. The reasons for this are hidden in a weakly decentralized state, partial reform steps taken exclusively from above to bottom, inefficient coordination of the subjects of regional development, but also in the unfavorable historical heritage in this area. In conclusion, we emphasize that the process of the accession of the Republic of Serbia to the European Union represents a great opportunity to balance its regional development, considering that the European Union is paying more and more attention to regional development through its institutions and mechanisms of regional policy. In the research, we will use methods of analysis and analysis of content of documents, case studies and comparative method.

Introduction the flow of endodontic sealer (ES) is the property that characterizes its velocity along the certain surface and depends on the friction force. The aim of this research was to measure the flow rate of three zinc oxide eugenol based ES's in various consistencies exposed to the load of 2 kg. Material and methods the experimental group included prepared samples of sealers protocoled by ADA specification No. 57 A) Endomethasone N in liquid:powder ratio of 1:5, 1:6, 1:7 (standard), 1:8 and 1:9 according to the manufacturer brochure depending on the clinical situation; B) Roth 801 as 1:7 (standard) and 1:8 mixtures C) Tubliseal EWT as standard preparation (base-catalyst 1:1). A volume of 0.05 ml sealer was spread on the glass plate and upon applying the load of 2 kg the diameter of sealer was measured. In the control group the sealer samples were loaded only by the weight of glass plate (0.1kg). Results Based on measured diameters of sealers, all of them satisfied ADA requirements for the flow (d>20mm) (Endomethasone - 20.7-27.8 mm; Roth 801-29.6-30.0 mm; Tubliseal -39.9 mm). The thin consistency of sealers (1:5, 1:6) showed significantly higher flow than standard mixture (1:7) (p < 0.05). Conclusion Tubliseal EWT sealer showed the highest flow rate, significantly different than standard mixtures (1:7) of Endomethasone N and Roth 801.

In this paper we will analyze the effects of one of the most important economic projects on the soil of Europe after the Second World War. It's about a series of measures for the recovery of the Spanish economy, which in economic theory is collectively referred to as the "Spanish Economic Miracle". Spain, after the Spanish Civil War, and then the Second World War, was an underdeveloped and impoverished country, and was closed to foreign countries in political and economic terms. A wide range of reforms was initiated by the Spanish dictator Francisco Franco, while in practice they were implemented by the so-called technocrats. The results on the business plan were very favorable, but they were stopped by the outbreak of the oil crisis in the 1970s. The conclusion is that the reforms resulted in a strong industrialization of the country, opening up to the European and world market, developing Spain's tourism potential, and creating a strong middle class population. In this paper we will use the case study method, comparative method and statistical analysis.

Introduction: Patients with acute poisoning constitute 3-5% of patients treated by emergency physicians. Aim of the study: Determine frequency and etiology of acute poisoning, and factors affecting the outcome. Materials and methods: A retrospective, observational study enrolled patients who were treated by teams of the Emergency Medical Service Novi Sad (EMS) in the period from 01.01.2011. to 31.12.2011. due to acute poisoning. Further diagnostics and therapy were implemented in the Emergency Center (EC). Results: 226 patients with symptoms of acute poisoning were included (53.5% men, 46.5% women). The average patient age was 37.1 years. The principal mode of toxins entry was oral (87.6%). Alcohol poisoning was present in 29.2%, benzodiazepines in 23.5%, combination of alcohol and psychotropic drugs in 14.2% of cases. Prehospital, infusion therapy was initiated in 31%, Naloxone® was given in 10.6% and flumazenil (Anexate®) in 6.2% patients. After detoxication measures and observation 76.5% of patients were referred to psychiatric evaluation. 0.9% of cases had a fatal outcome. Conclusion: Since successful treatment of acute intoxication depends on the quality of initial care, efficient access to EMS, identification of poisoning etiology (toxic substances), and implementation of non-specific treatment (provided the airway, infusion therapy, vomiting provocation) is a good basis for further treatment at hospital level.

Objective: To validate ultrasonographic criteria for examination of the major salivary glands in the diagnosis of primary Sjögren's syndrome (SS). Method: A total of 209 consecutive patients with rheumatic diseases were selected according to the American-European Consensus Group (AECG) classification criteria for SS. One hundred and fifteen patients had primary SS, 44 had secondary SS, and 50 had sicca symptoms, and 36 subjects served as asymptomatic controls. This cohort was analysed for size, echogenicity, parenchymal inhomogeneity, focal changes, and posterior borders of the major salivary glands by ultrasonography (US). A novel US score for parenchymal inhomogeneity (0-12) was assigned and its diagnostic accuracy evaluated. Results: Ultrasonographic abnormalities of salivary glands were detected in 107/115 (93.0%) patients with primary SS, in 12/44 (27.3%) with secondary SS, in 25/50 (50.0%) with sicca symptoms, and in 4/36 (11.1%) asymptomatic controls. Area under the receiver operating characteristic curve (AUC-ROC) for US inhomogeneity score was highly significant [0.96 +/- 0.01; 95% confidence interval (CI) 0.94-0.99, p < 0.000] for primary SS, with a sensitivity to specificity ratio of 91/83 for parotid and 93/90 for submandibular glands. Setting the cut-off US inhomogeneity score at 6 resulted in the best ratio of specificity (90.0%) to sensitivity (95.1%), with a positive predictive value of 72% and a negative predictive value of 96%. A US inhomogeneity score >or= 6 was closely correlated with positive biopsy (p < 0.000) and scintigraphy findings (p < 0.000). Conclusions: We demonstrate the high diagnostic value of a novel US score for parenchymal inhomogeneity (0-12) that could serve as a useful single US criterion in the evaluation of salivary gland involvement in primary SS. [ABSTRACT FROM AUTHOR]

The main problem for modern visible light face recognition has been accurate identification under variable environmental conditions. Thermal infrared facial images utilization in face recognition systems can provide a solution for problems related to uncontrolled environmental conditions, especially to those caused by illumination limitations. This paper compares the results of the use of visible light and thermal infrared imagery for face recognition based on the HOG feature descriptor. In particular, the paper suggests an optimal HOG cell to image size ratio in order to improve recognition accuracy and reduce computational complexity. Performance statistics are presented on facial images with different facial expressions. The obtained results support the conclusion that recognition with thermal infrared images is more robust and that fusion of sensors should be included for improving recognition accuracy.