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51. Melanoma

Author

Cinotti, Elisa, primary, Liso, Flavio Giulio, additional, Rubegni, Pietro, additional, and Perrot, Jean-Luc, additional

Published
2021
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55. The combination of dermoscopy and reflectance confocal microscopy increases the diagnostic confidence of amelanotic/hypomelanotic lentigo maligna.

Author

Pizzichetta, Maria Antonietta, Polesel, Jerry, Perrot, Jean Luc, Rubegni, Pietro, Stanganelli, Ignazio, Magi, Serena, Mazzoni, Laura, Farnetani, Francesca, Pellacani, Giovanni, Garutti, Mattia, Puglisi, Fabio, and Cinotti, Elisa

Abstract

The dermoscopic diagnosis of amelanotic/hypomelanotic lentigo maligna/lentigo maligna melanoma (AHLM/LMM) may be very difficult in its early stages because of lack of pigment. Reflectance confocal microscopy (RCM) is an imaging technique that is especially helpful for the diagnosis of lentigo maligna. To determine the diagnostic performances of dermoscopy and RCM in the diagnosis of AHLM/LMMs we evaluated dermoscopic and RCM images of consecutive cases of histopathologically confirmed AHLM/LMMs, amelanotic/hypomelanotic basal cell carcinoma and squamous cell carcinoma (AHBCCs/AHSCCs), amelanotic/hypomelanotic benign lesions (AHBLs), and actinic keratoses (AKs) from five participating centers. Sensitivity, specificity, accuracy, predictive values, and level of diagnosis confidence were calculated for both diagnostic procedures. Both dermoscopy and RCM showed diagnostic performance >97% in the diagnosis of AHLM/LMMs versus AHBCC/AHSCCs and their combination slightly improved diagnostic performance, with accuracy increasing from 98.0% to 99.1%. Similarly, RCM in combination with dermoscopy showed a tiny increase in the diagnostic performance in the diagnosis of AHLM/LMMs versus AHBLs (accuracy increased from 87.2% to 88.8%) and versus AKs (accuracy increased from 91.4% to 93.4%). Although the increase in diagnostic performance due to RCM was modest, the combination of dermoscopy and RCM greatly increased the level of confidence; high confidence in the diagnosis of AHLM/LMMs versus AHBLs increased from 36.2% with dermoscopy alone to 76.6% with dermoscopy plus RMC. Based on our results, dermoscopy and RCM should be complementary to improve not only diagnostic accuracy but also the level of diagnostic certainty in the diagnosis of AHLM/LMMs. [ABSTRACT FROM AUTHOR]

Published
2024
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56. A European Multicentric Investigation of Atypical Melanocytic Skin Lesions of Palms and Soles: The iDScore-PalmoPlantar Database.

Author

Tognetti, Linda, Cartocci, Alessandra, Lallas, Aimilios, Moscarella, Elvira, Stanganelli, Ignazio, Nazzaro, Gianluca, Paoli, John, Fargnoli, Maria Concetta, Broganelli, Paolo, Kittler, Harald, Perrot, Jean-Luc, Cataldo, Gennaro, Cevenini, Gabriele, Lo Conte, Sofia, Simone, Leonardelli, Cinotti, Elisa, and Rubegni, Pietro

Subjects
DYSPLASTIC nevus syndrome, DATABASES, HAIR dyeing & bleaching, PALMS, DERMOSCOPY, NEVUS
Abstract

Background: The differential diagnosis of atypical melanocytic palmoplantar skin lesions (aMPLs) represents a diagnostic challenge, including atypical nevi (AN) and early melanomas (MMs) that display overlapping clinical and dermoscopic features. We aimed to set up a multicentric dataset of aMPL dermoscopic cases paired with multiple anamnestic risk factors and demographic and morphologic data. Methods: Each aMPL case was paired with a dermoscopic and clinical picture and a series of lesion-related data (maximum diameter value; location on the palm/sole in 17 areas; histologic diagnosis; and patient-related data (age, sex, family history of melanoma/sunburns, phototype, pheomelanin, eye/hair color, multiple/dysplastic body nevi, and traumatism on palms/soles). Results: A total of 542 aMPL cases—113 MM and 429 AN—were collected from 195 males and 347 females. No sex prevalence was found for melanomas, while women were found to have relatively more nevi. Melanomas were prevalent on the heel, plantar arch, and fingers in patients aged 65.3 on average, with an average diameter of 17 mm. Atypical nevi were prevalent on the plantar arch and palmar area of patients aged 41.33 on average, with an average diameter of 7 mm. Conclusions: Keeping in mind the risk profile of an aMPL patient can help obtain a timely differentiation between malignant/benign cases, thus avoiding delayed and inappropriate excision, respectively, with the latter often causing discomfort/dysfunctional scarring, especially at acral sites. [ABSTRACT FROM AUTHOR]

Published
2024
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58. Dermoscopic criteria explained by LC‐OCT: negative maple leaf like areas

Author

Palmisano, Gerardo, primary, Orte Cano, Carmen, additional, Fontaine, Margot, additional, Lenoir, Clément, additional, Cinotti, Elisa, additional, Tognetti, Linda, additional, Rubegni, Pietro, additional, Perez‐Anker, Javiera, additional, Puig, Susana, additional, Malvehy, Josep, additional, Perrot, Jean‐Luc, additional, del Marmol, Véronique, additional, Peris, Ketty, additional, and Suppa, Mariano, additional

Published
2023
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59. Impact of Baricitinib on Patients’ Quality of Life after One Year of Treatment for Atopic Dermatitis in Real-World Practice: Results of the Observatory of Chronic Inflammatory Skin Diseases Registry

Author

Reguiai, Ziad, primary, Becherel, Pierre André, additional, Perrot, Jean Luc, additional, Fougerousse, Anne Claire, additional, Begon, Edouard, additional, Poreaux, Claire, additional, Boulard, Claire, additional, Chaby, Guillaume, additional, Fite, Charlotte, additional, Zaraa, Inès, additional, Lons-Danic, Dominique, additional, Liegeon, Anne-Laure, additional, Parier, Josiane, additional, Quiles-Tsimaratos, Nathalie, additional, David, Laurene, additional, and Maccari, François, additional

Published
2023
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61. Dermoscopy of atypical pigmented lesions of the face: Variation according to facial areas

Author

Tognetti, Linda, primary, Cartocci, Alessandra, additional, Cinotti, Elisa, additional, Donghia, Martina, additional, Żychowska, Magdalena, additional, Moscarella, Elvira, additional, Dika, Emi, additional, Farnetani, Francesca, additional, Guida, Stefania, additional, Paoli, John, additional, Lallas, Aimilios, additional, Tiodorovic, Danica, additional, Stanganelli, Ignazio, additional, Longo, Caterina, additional, Suppa, Mariano, additional, Zalaudek, Iris, additional, Argenziano, Giuseppe, additional, Perrot, Jean Luc, additional, Rubegni, Giovanni, additional, Cataldo, Gennaro, additional, and Rubegni, Pietro, additional

Published
2023
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62. Reflectance Confocal Microscopy in Dermatology

Author

Cinotti, Elisa, primary, Perrot, Jean Luc, additional, Labeille, Bruno, additional, González, Salvador, additional, Bassoli, Sara, additional, Longo, Caterina, additional, Pellacani, Giovanni, additional, Giuffrida, Roberta, additional, Zalaudek, Iris, additional, Arzberger, Edith J., additional, Debarbieux, Sébastien, additional, Amini-Adle, Mona, additional, Thomas, Luc, additional, Suppa, Mariano, additional, Veronique, Del Marmol, additional, Bahadoran, Philippe, additional, Malvehy, Josep, additional, Benassar, Antoni, additional, Pérez, Javiera, additional, and Cambazard, Frédéric, additional

Published
2020
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65. The role of line‐field confocal optical coherence tomography in the differential diagnosis of infiltrative basal cell carcinoma with scar‐like lesions: A case series

Author

Aktas, Dina, primary, Palmisano, Gerardo, additional, Cinotti, Elisa, additional, Tognetti, Linda, additional, Perrot, Jean‐Luc, additional, Perez‐Anker, Javiera, additional, Rubegni, Pietro, additional, Puig, Susana, additional, Malvehy, Josep, additional, Peris, Ketty, additional, del Marmol, Veronique, additional, and Suppa, Mariano, additional

Published
2023
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66. A risk‐scoring model for the differential diagnosis of lentigo maligna and other atypical pigmented facial lesions of the face: the facial iDScore

Author

Tognetti, Linda, primary, Cartocci, Alessandra, additional, Żychowska, Magdalena, additional, Savarese, Imma, additional, Cinotti, Elisa, additional, Pizzichetta, Maria Antonietta, additional, Moscarella, Elvira, additional, Longo, Caterina, additional, Farnetani, Francesca, additional, Guida, Stefania, additional, Paoli, John, additional, Lallas, Aimilios, additional, Tiodorovic, Danica, additional, Stanganelli, Ignazio, additional, Magi, Serena, additional, Dika, Emi, additional, Zalaudek, Iris, additional, Suppa, Mariano, additional, Argenziano, Giuseppe, additional, Pellacani, Giovanni, additional, Perrot, Jean Luc, additional, Miracapillo, Chiara, additional, Rubegni, Giovanni, additional, Cevenini, Gabriele, additional, and Rubegni, Pietro, additional

Published
2023
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68. Line‐field confocal optical coherence tomography can help differentiating melanoma from pigmented basal cell carcinoma: A case report

Author

Wolswijk, Tom, primary, Sanak, Dilara, additional, Lenoir, Clément, additional, Cinotti, Elisa, additional, Tognetti, Linda, additional, Rubegni, Pietro, additional, Perez‐Anker, Javiera, additional, Puig, Susana, additional, Malvehy, Josep, additional, Perrot, Jean‐Luc, additional, Mosterd, Klara, additional, del Marmol, Véronique, additional, and Suppa, Mariano, additional

Published
2023
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72. VEXAS syndrome following COVID‐19 mRNA vaccination

Author

Skowron, François, primary, Klepfisch, Lucas, additional, Guillaume, Laurent, additional, Godeneche, Janique, additional, Facile, Anthony, additional, Gombert, Martin, additional, Pechuzal, Suzann, additional, and Perrot, Jean‐Luc, additional

Published
2023
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74. The role of line-field confocal optical coherence tomography in the differential diagnosis of infiltrative basal cell carcinoma with scar-like lesions: A case series

Author

Aktas, Dina, Palmisano, Gerardo, Cinotti, Elisa, Tognetti, Linda, Perrot, Jean-Luc, Perez-Anker, Javiera, Rubegni, Pietro, Puig, Susana, Malvehy, Josep, Peris, Ketty, Del Marmol, Veronique, Suppa, Mariano, Peris, Ketty (ORCID:0000-0002-5237-0463), Aktas, Dina, Palmisano, Gerardo, Cinotti, Elisa, Tognetti, Linda, Perrot, Jean-Luc, Perez-Anker, Javiera, Rubegni, Pietro, Puig, Susana, Malvehy, Josep, Peris, Ketty, Del Marmol, Veronique, Suppa, Mariano, and Peris, Ketty (ORCID:0000-0002-5237-0463)

Abstract

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Published
2023

75. Line-Field Confocal Optical Coherence Tomography for the Diagnosis of Skin Carcinomas: Real-Life Data over Three Years

Author

Donelli, Carolina, Suppa, Mariano, Tognetti, Linda, Perrot, Jean Luc Uc J.L., Calabrese, Laura, Perez-Anker, Javiera, Malvehy, Josep, Rubegni, Pietro, Cinotti, Elisa, Donelli, Carolina, Suppa, Mariano, Tognetti, Linda, Perrot, Jean Luc Uc J.L., Calabrese, Laura, Perez-Anker, Javiera, Malvehy, Josep, Rubegni, Pietro, and Cinotti, Elisa

Abstract

Line-field confocal optical coherence tomography (LC-OCT) can help the clinical diagnosis of skin diseases. The present study aimed to evaluate the sensitivity, specificity, and diagnostic accuracy of LC-OCT for the diagnosis of the most frequent non-melanoma skin cancers (NMSCs), i.e. basal cell carcinoma (BCC) and squamous cell carcinoma (SCC). Comparing LC-OCT diagnostic performances with those of dermoscopy, histopathological examination was used as a gold standard. For every study endpoint, the diagnostic ability of LC-OCT revealed superiority over the dermoscopic examination. In particular, a significant increase in specificity was observed. Sensitivity, specificity, and diagnostic accuracy of dermoscopy and LC-OCT for the diagnosis of malignancy were, respectively, 0.97 (CI 0.94–0.99), 0.43 (CI 0.36–0.51), and 0.77 (CI 0.72–0.81) for dermoscopy and 0.99 (CI 0.97–1.00), 0.90 (CI 0.84–0.94), and 0.96 (CI 0.93–0.97) for LC-OCT. The positive predictive value (PPV) resulted in 0.74 (CI 0.69–0.78) for dermoscopy and 0.94 (CI 0.91–0.97) for LC-OCT, and the negative predictive value (NPV) was 0.89 (CI 0.81–0.95) for dermoscopy and 0.98 (CI 0.95–1.00) for LC-OCT. Finally, our real-life study showed a potentially important role of LC-OCT in the non-invasive diagnosis of NMSCs, especially BCC. The real-time imaging technique could spare unnecessary biopsies with an increased sensitivity, a much higher specificity, and better accuracy than clinical assessment with dermoscopy alone., SCOPUS: ar.j, info:eu-repo/semantics/published

Published
2023

76. Diagnostic Accuracy of Line-Field Confocal Optical Coherence Tomography for the Diagnosis of Skin Carcinomas

Author

Cinotti, Elisa, Brunetti, Tullio, Cartocci, Alessandra, Tognetti, Linda, Suppa, Mariano, Malvehy, Josep, Perez-Anker, Javiera, Puig, S., Perrot, Jean Luc Uc J.L., Rubegni, Pietro, Cinotti, Elisa, Brunetti, Tullio, Cartocci, Alessandra, Tognetti, Linda, Suppa, Mariano, Malvehy, Josep, Perez-Anker, Javiera, Puig, S., Perrot, Jean Luc Uc J.L., and Rubegni, Pietro

Abstract

Line-field confocal optical coherence tomography (LC-OCT) is a new, noninvasive imaging technique for the diagnosis of skin cancers. A total of 243 benign (54%) and malignant (46%) skin lesions were consecutively enrolled from 27 August 2020, to 6 October 2021 at the Dermatology Department of the University Hospital of Siena, Italy. Dermoscopic- and LC-OCT-based diagnoses were given by an expert dermatologist and compared with the ground truth. Considering all types of malignant skin tumours (79 basal cell carcinomas (BCCs), 22 squamous cell carcinomas, and 10 melanomas), a statistically significant increase (p = 0.013) in specificity was observed from dermoscopy (0.73, CI 0.64–0.81) to LC-OCT (0.87, CI 0.79–0.93) while sensitivity was the same with the two imaging techniques (0.95 CI 0.89–0.98 for dermoscopy and 0.95 CI 0.90–0.99 for LC-OCT). The increase in specificity was mainly driven by the ability of LC-OCT to differentiate BCCs from other diagnoses. In conclusion, our real-life study showed that LC-OCT can play an important role in helping the noninvasive diagnosis of malignant skin neoplasms and especially of BCCs. LC-OCT could be positioned after the dermoscopic examination, to spare useless biopsy of benign lesions without decreasing sensitivity., SCOPUS: ar.j, info:eu-repo/semantics/published

Published
2023

77. Line-Field Confocal Optical Coherence Tomography (LC-OCT) for Skin Imaging in Dermatology

Author

Latriglia, Flora, Ogien, Jonas, Tavernier, Clara, Fischman, Sébastien, Suppa, Mariano, Perrot, Jean Luc Uc J.L., Dubois, Arnaud, Latriglia, Flora, Ogien, Jonas, Tavernier, Clara, Fischman, Sébastien, Suppa, Mariano, Perrot, Jean Luc Uc J.L., and Dubois, Arnaud

Abstract

Line-field confocal optical coherence tomography (LC-OCT) is a non-invasive optical imaging technique based on a combination of the principles of optical coherence tomography and reflectance confocal microscopy with line-field illumination, which can generate cell-resolved images of the skin in vivo. This article reports on the LC-OCT technique and its application in dermatology. The principle of the technique is described, and the latest technological innovations are presented. The technology has been miniaturized to fit within an ergonomic handheld probe, allowing for the easy access of any skin area on the body. The performance of the LC-OCT device in terms of resolution, field of view, and acquisition speed is reported. The use of LC-OCT in dermatology for the non-invasive detection, characterization, and therapeutic follow-up of various skin pathologies is discussed. Benign and malignant melanocytic lesions, non-melanocytic skin tumors, such as basal cell carcinoma, squamous cell carcinoma and actinic keratosis, and inflammatory and infectious skin conditions are considered. Dedicated deep learning algorithms have been developed for assisting in the analysis of LC-OCT images of skin lesions., SCOPUS: ar.j, info:eu-repo/semantics/published

Published
2023

78. Dermoscopic criteria explained by LC‐OCT: Negative maple leaf‐like areas.

Author

Palmisano, Gerardo, Orte Cano, Carmen, Fontaine, Margot, Lenoir, Clément, Cinotti, Elisa, Tognetti, Linda, Rubegni, Pietro, Perez‐Anker, Javiera, Puig, Susana, Malvehy, Josep, Perrot, Jean‐Luc, del Marmol, Véronique, Peris, Ketty, and Suppa, Mariano

Subjects
DERMOSCOPY, BASAL cell carcinoma, SKIN cancer, OPTICAL coherence tomography
Abstract

This article discusses a new dermoscopic criterion for diagnosing basal cell carcinoma (BCC) called "negative maple-leaf-like areas" (NMLLAs). NMLLAs are round, nonpigmented structures with a whitish background and well-defined borders. They are associated with superficial BCC and correspond to non-pigmented tumor nests at the dermal-epidermal junction level. The article also introduces a new technology called line-field confocal optical coherence tomography (LC-OCT), which combines the advantages of reflectance confocal microscopy (RCM) and conventional OCT. LC-OCT allows for a precise correlation of dermoscopic criteria with skin images. The article presents a case study that demonstrates the correlation between NMLLAs seen in dermoscopy and hemispheric BCC lobules observed with LC-OCT. The use of LC-OCT may help clinicians identify NMLLAs, which can be difficult to recognize. Further studies are needed to confirm this hypothesis. [Extracted from the article]

Published
2024
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79. Development and Implementation of a Web-Based International Registry Dedicated to Atypical Pigmented Skin Lesions of the Face: Teledermatologic Investigation on Epidemiology and Risk Factors.

Author

Tognetti, Linda, Cinotti, Elisa, Farnetani, Francesca, Lallas, Aimilios, Paoli, John, Longo, Caterina, Pampena, Riccardo, Moscarella, Elvira, Argenziano, Giuseppe, Tiodorovic, Danica, Stanganelli, Ignazio, Magi, Serena, Suppa, Mariano, del Marmol, Veronique, Dika, Emi, Zelin, Enrico, Zalaudek, Iris, Pizzichetta, Maria Antonietta, Pellacani, Giovanni, and Perrot, Jean Luc

Subjects
DYSPLASTIC nevus syndrome, NEVUS, BLACKBERRIES, EPIDEMIOLOGY, PATIENTS' families, HAIR dyeing & bleaching, DISEASE risk factors
Abstract

Background:Atypical pigmented facial lesions (aPFLs) often display clinical and dermoscopic equivocal and/or overlapping features, thus causing a challenging and delayed diagnosis and/or inappropriate excisions. No specific registry dedicated to aPFL paired with clinical data is available to date. Methods: The dataset is hosted on a specifically designed web platform. Each complete case was composed of the following data: (1) one dermoscopic picture; (2) one clinical picture; (3) two lesion data, that is, maximum diameter and facial location (e.g., orbital area/forehead/nose/cheek/chin/mouth); (4) patient's demographics: family history of melanoma, history of sunburns in childhood, phototype, pheomelanine, eyes/hair color, multiple nevi/dysplastic nevi on the body; and (5) acquisition device (videodermatoscope/camera-based/smartphone-based system). Results:A total of 11 dermatologic centers contributed to a final teledermoscopy database of 1,197 aPFL with a distribution of 353 lentigo maligna (LM), 146 lentigo maligna melanoma (LMM), 231 pigmented actinic keratoses, 266 solar lentigo, 125 atypical nevi, 48 seborrheic keratosis, and 28 seborrheic-lichenoid keratoses. The cheek site was involved in half of aPFL cases (50%). Compared with those with the other aPFL cases, patients with LM/LMM were predominantly men, older (69.32 ± 12.9 years on average vs. 62.69 ± 14.51), exhibited larger lesions (11.88 ± 7.74 mm average maximum diameter vs. 9.33 ± 6.46 mm), and reported a positive history of sunburn in childhood. Conclusions:The iDScore facial dataset currently represents a precious source of data suitable for the design of diagnostic support tools based on risk scoring classifiers to help dermatologists in recognizing LM/LMM among challenging aPFL in clinical practice. [ABSTRACT FROM AUTHOR]

Published
2023
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83. Morphological evaluation of melanocytic lesions with three-dimensional line-field confocal optical coherence tomography: correlation with histopathology and reflectance confocal microscopy. A pilot study

Author

Perez-Anker, Javiera, primary, Puig, Susana, additional, Alos, Llucia, additional, García, Adriana, additional, Alejo, Beatriz, additional, Cinotti, Elisa, additional, Orte Cano, Carmen, additional, Tognetti, Linda, additional, Lenoir, Clement, additional, Monnier, Jilliana, additional, Machuca, Natalia, additional, Castillo, Paola, additional, Gibert, Pau Rosés, additional, Rubegni, Pietro, additional, Suppa, Mariano, additional, Perrot, Jean Luc, additional, del Marmol, Veronique, additional, and Malvehy, Josep, additional

Published
2022
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85. Comparison of reflectance confocal microscopy and line‐field optical coherence tomography for the identification of keratinocyte skin tumours

Author

Cinotti, Elisa, primary, Bertello, Martina, additional, Cartocci, Alessandra, additional, Fiorani, Diletta, additional, Tognetti, Linda, additional, Solmi, Valentina, additional, Cappilli, Simone, additional, Peris, Ketty, additional, Perrot, Jean Luc, additional, Suppa, Mariano, additional, Del Marmol, Veronique, additional, and Rubegni, Pietro, additional

Published
2022
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92. How to Define Mild to Severe Hidradenitis Suppurativa? A Simple New Tool Based on Latent Class Analysis of EPIVER Data Study

Author

Perrot,Jean-Luc, Maccari,François, Guillem,Philippe, Fougerousse,Anne-Claire, Nassif,Aude, Beneton,Nathalie, Cinotti,Elisa, Girard,Céline, Binois,Raphaelle, Reguiaï,Ziad, Perrot,Jean-Luc, Maccari,François, Guillem,Philippe, Fougerousse,Anne-Claire, Nassif,Aude, Beneton,Nathalie, Cinotti,Elisa, Girard,Céline, Binois,Raphaelle, and Reguiaï,Ziad

Abstract

Jean-Luc Perrot,1,2 François Maccari,2,3 Philippe Guillem,2,4– 6 Anne-Claire Fougerousse,2,7 Aude Nassif,2,8 Nathalie Beneton,2,9 Elisa Cinotti,2,10 Céline Girard,2,11 Raphaelle Binois,2,12 Ziad Reguiaï2,13 On behalf of the ResoVerneuil group1Department of Dermatology, University Hospital of Saint-Etienne, Saint-Etienne, France; 2ResoVerneuil, Ville, France; 3Private Office, La Varenne St Hilaire, France; 4Service de chirurgie adulte, clinique du Val-d’Ouest, Ecully, 69130, France; 5European Hidradenitis Suppurativa Foundation, Dessau, Germany; 6Groupe de Recherche En proctologie de la Société Nationale Francophone de Colo-Proctologie, Paris, France; 7Military Teaching Hospital Bégin, Saint Mandé, France; 8Centre Médical de l’Institut Pasteur, Paris, 75015, France; 9Dermatology Department, Centre Hospitalier du Mans, Le Mans, France; 10Department of Medical, Dermatology Unit, Surgical and Neuro.Sciences, University of Siena, Siena, Italy; 11Dermatology Department, Centre Hospitalier Universitaire de Montpellier, Montpellier, France; 12Dermatology Department, Centre Hospitalier Régional d’Orléans, Orléans Cedex, 45067, France; 13Service de dermatologie, polyclinique Courlancy, Reims, 51100, FranceCorrespondence: Jean-Luc Perrot, Department of Dermatology, University Hospital of Saint-Etienne, Saint-Etienne, France, Email j.luc.perrot@chu-st-etienne.frPurpose: Hidradenitis suppurativa (HS) is an inflammatory skin disease characterized by recurrent or chronic painful and suppurating lesions in the apocrine gland-bearing regions. The lack of knowledge about HS and its extremely heterogeneous clinical presentation, in terms of both lesion appearance and sites of involvement, frequently delay its diagnosis for several years. Objectives: in this study, using the latent class analysis, it was demonstrated that severit

Published
2022

99. Three-dimensional microscopic quantification of in vivo healthy epidermis based on line-field confocal optical coherence tomography (LC-OCT) assisted by artificial intelligence

Author

Ogien, Jonas, primary, Chauvel-Picard, Julie, additional, Bérot, Vincent, additional, Tognetti, Linda, additional, Orte Cano, Carmen, additional, Fontaine, Margot, additional, Lenoir, Clément, additional, Perez-Anker, Javiera, additional, Puig, Susana, additional, Dubois, Arnaud, additional, Forestier, Sandra, additional, Monnier, Jilliana, additional, Jdid, Randa, additional, Cazorla, Gabriel, additional, Pedrazzani, Mélanie, additional, Sanchez, Antoine, additional, Fischman, Sébastien, additional, Rubegni, Pietro, additional, del Marmol, Véronique, additional, Malvehy, Josep, additional, Cinotti, Elisa, additional, Perrot, Jean-Luc, additional, and Suppa, Mariano, additional

Published
2022
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