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413 results on '"Peng, Xiaoli"'

91. Flavonoids, flavonoid subclasses and breast cancer risk: a meta-analysis of epidemiologic studies.

Author

Chang Hui, Xie Qi, Zhang Qianyong, Peng Xiaoli, Zhu Jundong, and Mi Mantian

Subjects
Medicine, Science
Abstract

BackgroundStudies have suggested the chemopreventive effects of flavonoids on carcinogenesis. Yet numbers of epidemiologic studies assessing dietary flavonoids and breast cancer risk have yielded inconsistent results. The association between flavonoids, flavonoid subclasses (flavonols, flavan-3-ols, etc.) and the risk of breast cancer lacks systematic analysis.ObjectiveWe aimed to examine the association between flavonoids, each flavonoid subclass (except isoflavones) and the risk of breast cancer by conducting a meta-analysis.DesignWe searched for all relevant studies with a prospective cohort or case-control study design published before July 1(st), 2012, using Cochrane library, MEDLINE, EMBASE and PUBMED. Summary relative risks (RR) were calculated using fixed- or random-effects models. All analyses were performed using STATA version 10.0.ResultsTwelve studies were included, involving 9 513 cases and 181 906 controls, six of which were prospective cohort studies, and six were case-control studies. We calculated the summary RRs of breast cancer risk for the highest vs lowest categories of each flavonoid subclass respectively. The risk of breast cancer significantly decreased in women with high intake of flavonols (RR=0.88, 95% CI 0.80-0.98) and flavones (RR=0.83, 95% CI: 0.76-0.91) compared with that in those with low intake of flavonols and flavones. However, no significant association of flavan-3-ols (RR=0.93, 95% CI: 0.84-1.02), flavanones (summary RR=0.95, 95% CI: 0.88-1.03), anthocyanins (summary RR=0.97, 95% CI: 0.87-1.08) or total flavonoids (summary RR=0.98, 95% CI: 0.86-1.12) intake with breast cancer risk was observed. Furthermore, summary RRs of 3 case-control studies stratified by menopausal status suggested flavonols, flavones or flavan-3-ols intake is associated with a significant reduced risk of breast cancer in post-menopausal while not in pre-menopausal women.ConclusionsThe present study suggests the intake of flavonols and flavones, but not other flavonoid subclasses or total flavonoids, is associated with a decreased risk of breast cancer, especially among post-menopausal women.

Published
2013
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93. Identification of Plectropomus leopardus, Promicrops lanceolatus and Cromileptes altivelis using species-specific TaqMan real-time PCR

Author

Lin Shuangqing, Xu Qiubei, Peng Xiaoli, and Shuangya Chen

Subjects
Leopardus, Mitochondrial DNA, Aquatic product, biology, Plectropomus, Ecology, 010401 analytical chemistry, Zoology, 04 agricultural and veterinary sciences, biology.organism_classification, 040401 food science, 01 natural sciences, 0104 chemical sciences, 0404 agricultural biotechnology, Real-time polymerase chain reaction, TaqMan, %22">Fish , Identification (biology), Food Science, Biotechnology
Abstract

Plectropomus leopardus , Promicrops lanceolatus and Cromileptes altivelis are high-value groupers in chinese aquatic product market and are substituted by cheaper ones sometimes due to economic profit. In this study, real-time PCR methods for identification of these groupers were developed. Species-specific primers and probes were designed on the basis of cytochrome oxidase I (COI) mitochondrial DNA sequences of groupers and other fishes. The specificity of the real time PCR assays were tested with a total of 51 specimens of fish, meat and poultry. Amplifications were observed in specific species only. The methods developed were accurate and rapid and offered the potential to detect fraudulent or unintentional mislabeling of these species in routine seafood authentication analysis.

Published
2018

99. Association of occupational stress, period circadian regulator 3 (PER3) gene polymorphism and their interaction with poor sleep quality.

Author

Peng, Xiaoli, Li, Ju, Han, Bin, Zhu, Yanfeng, Cheng, Daomei, Li, Qiyu, and Du, Jingchang

Subjects
*JOB stress, *CLOCK genes, *GENETIC polymorphisms, *SLEEP, *NON-REM sleep, *TANDEM repeats, *POLYMERASE chain reaction, *JOB analysis
Abstract

Summary: Occupational stress is associated with sleep quality among workers and the human variable number tandem repeat (VNTR) polymorphism of the period circadian regulator 3 (PER3) gene relates to sleep–wake regulation. The main aims of the present study were to examine the effects of PER3 VNTR genotypes, occupational stress, and their interactions on sleep quality. A cross‐sectional study was conducted and 729 workers were recruited in Sichuan. Sleep quality were assessed using the Pittsburgh Sleep Quality Index. Occupational stress was measured using the Generic Job Stress Questionnaire. PER3 genotypes were determined with polymerase chain reaction. High and medium occupational stress were linked to a higher risk of poor sleep quality than low levels. Unconditional logistic regression indicated that PER3 genotype was significantly associated with sleep quality, and an increased risk of poor sleep of >1.5‐times was observed in those with the allele 5 compared to allele 4. The 5/5 genotype was associated with both sleep latency and sleep duration. Crossover analysis showed an occupational stress × PER3 interaction. Compared to subjects with both low and medium occupational stress and 4/4 + 4/5 genotype, those with both high occupational stress and 5/5 genotype had a higher risk of poor sleep quality. Stratified logistic analyses found that compared with low and medium occupational stress, high occupational stress increased the risk of poor sleep by more than five‐times in 5/5 genotype carriers. Occupational stress and PER3 genotype had both separate and combined effects on poor sleep quality of workers. The results suggest that occupational stress may increase the risk of poor sleep quality through interaction with the PER3 gene polymorphism. [ABSTRACT FROM AUTHOR]

Published
2022
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