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51. Supplementary Figures S1 through S28 from Early Effector T Lymphocytes Coexpress Multiple Inhibitory Receptors in Primary Non–Small Cell Lung Cancer

Author

Tassi, Elena, primary, Grazia, Giulia, primary, Vegetti, Claudia, primary, Bersani, Ilaria, primary, Bertolini, Giulia, primary, Molla, Alessandra, primary, Baldassari, Paola, primary, Andriani, Francesca, primary, Roz, Luca, primary, Sozzi, Gabriella, primary, Pastorino, Ugo, primary, Mortarini, Roberta, primary, and Anichini, Andrea, primary

Published
2023
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52. Supplementary Table 2 from KAT6B Is a Tumor Suppressor Histone H3 Lysine 23 Acetyltransferase Undergoing Genomic Loss in Small Cell Lung Cancer

Author

Simó-Riudalbas, Laia, primary, Pérez-Salvia, Montserrat, primary, Setien, Fernando, primary, Villanueva, Alberto, primary, Moutinho, Catia, primary, Martínez-Cardús, Anna, primary, Moran, Sebastian, primary, Berdasco, Maria, primary, Gomez, Antonio, primary, Vidal, Enrique, primary, Soler, Marta, primary, Heyn, Holger, primary, Vaquero, Alejandro, primary, de la Torre, Carolina, primary, Barceló-Batllori, Silvia, primary, Vidal, August, primary, Roz, Luca, primary, Pastorino, Ugo, primary, Szakszon, Katalin, primary, Borck, Guntram, primary, Moura, Conceição S., primary, Carneiro, Fátima, primary, Zondervan, Ilse, primary, Savola, Suvi, primary, Iwakawa, Reika, primary, Kohno, Takashi, primary, Yokota, Jun, primary, and Esteller, Manel, primary

Published
2023
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53. Supplementary Table 1 from KAT6B Is a Tumor Suppressor Histone H3 Lysine 23 Acetyltransferase Undergoing Genomic Loss in Small Cell Lung Cancer

Author

Simó-Riudalbas, Laia, primary, Pérez-Salvia, Montserrat, primary, Setien, Fernando, primary, Villanueva, Alberto, primary, Moutinho, Catia, primary, Martínez-Cardús, Anna, primary, Moran, Sebastian, primary, Berdasco, Maria, primary, Gomez, Antonio, primary, Vidal, Enrique, primary, Soler, Marta, primary, Heyn, Holger, primary, Vaquero, Alejandro, primary, de la Torre, Carolina, primary, Barceló-Batllori, Silvia, primary, Vidal, August, primary, Roz, Luca, primary, Pastorino, Ugo, primary, Szakszon, Katalin, primary, Borck, Guntram, primary, Moura, Conceição S., primary, Carneiro, Fátima, primary, Zondervan, Ilse, primary, Savola, Suvi, primary, Iwakawa, Reika, primary, Kohno, Takashi, primary, Yokota, Jun, primary, and Esteller, Manel, primary

Published
2023
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54. Supplementary Figure 6 from KAT6B Is a Tumor Suppressor Histone H3 Lysine 23 Acetyltransferase Undergoing Genomic Loss in Small Cell Lung Cancer

Author

Simó-Riudalbas, Laia, primary, Pérez-Salvia, Montserrat, primary, Setien, Fernando, primary, Villanueva, Alberto, primary, Moutinho, Catia, primary, Martínez-Cardús, Anna, primary, Moran, Sebastian, primary, Berdasco, Maria, primary, Gomez, Antonio, primary, Vidal, Enrique, primary, Soler, Marta, primary, Heyn, Holger, primary, Vaquero, Alejandro, primary, de la Torre, Carolina, primary, Barceló-Batllori, Silvia, primary, Vidal, August, primary, Roz, Luca, primary, Pastorino, Ugo, primary, Szakszon, Katalin, primary, Borck, Guntram, primary, Moura, Conceição S., primary, Carneiro, Fátima, primary, Zondervan, Ilse, primary, Savola, Suvi, primary, Iwakawa, Reika, primary, Kohno, Takashi, primary, Yokota, Jun, primary, and Esteller, Manel, primary

Published
2023
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55. Supplementary Figure 3 from KAT6B Is a Tumor Suppressor Histone H3 Lysine 23 Acetyltransferase Undergoing Genomic Loss in Small Cell Lung Cancer

Author

Simó-Riudalbas, Laia, primary, Pérez-Salvia, Montserrat, primary, Setien, Fernando, primary, Villanueva, Alberto, primary, Moutinho, Catia, primary, Martínez-Cardús, Anna, primary, Moran, Sebastian, primary, Berdasco, Maria, primary, Gomez, Antonio, primary, Vidal, Enrique, primary, Soler, Marta, primary, Heyn, Holger, primary, Vaquero, Alejandro, primary, de la Torre, Carolina, primary, Barceló-Batllori, Silvia, primary, Vidal, August, primary, Roz, Luca, primary, Pastorino, Ugo, primary, Szakszon, Katalin, primary, Borck, Guntram, primary, Moura, Conceição S., primary, Carneiro, Fátima, primary, Zondervan, Ilse, primary, Savola, Suvi, primary, Iwakawa, Reika, primary, Kohno, Takashi, primary, Yokota, Jun, primary, and Esteller, Manel, primary

Published
2023
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56. Supplementary Figure 8 from KAT6B Is a Tumor Suppressor Histone H3 Lysine 23 Acetyltransferase Undergoing Genomic Loss in Small Cell Lung Cancer

Author

Simó-Riudalbas, Laia, primary, Pérez-Salvia, Montserrat, primary, Setien, Fernando, primary, Villanueva, Alberto, primary, Moutinho, Catia, primary, Martínez-Cardús, Anna, primary, Moran, Sebastian, primary, Berdasco, Maria, primary, Gomez, Antonio, primary, Vidal, Enrique, primary, Soler, Marta, primary, Heyn, Holger, primary, Vaquero, Alejandro, primary, de la Torre, Carolina, primary, Barceló-Batllori, Silvia, primary, Vidal, August, primary, Roz, Luca, primary, Pastorino, Ugo, primary, Szakszon, Katalin, primary, Borck, Guntram, primary, Moura, Conceição S., primary, Carneiro, Fátima, primary, Zondervan, Ilse, primary, Savola, Suvi, primary, Iwakawa, Reika, primary, Kohno, Takashi, primary, Yokota, Jun, primary, and Esteller, Manel, primary

Published
2023
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57. Supplementary Table 3 from KAT6B Is a Tumor Suppressor Histone H3 Lysine 23 Acetyltransferase Undergoing Genomic Loss in Small Cell Lung Cancer

Author

Simó-Riudalbas, Laia, primary, Pérez-Salvia, Montserrat, primary, Setien, Fernando, primary, Villanueva, Alberto, primary, Moutinho, Catia, primary, Martínez-Cardús, Anna, primary, Moran, Sebastian, primary, Berdasco, Maria, primary, Gomez, Antonio, primary, Vidal, Enrique, primary, Soler, Marta, primary, Heyn, Holger, primary, Vaquero, Alejandro, primary, de la Torre, Carolina, primary, Barceló-Batllori, Silvia, primary, Vidal, August, primary, Roz, Luca, primary, Pastorino, Ugo, primary, Szakszon, Katalin, primary, Borck, Guntram, primary, Moura, Conceição S., primary, Carneiro, Fátima, primary, Zondervan, Ilse, primary, Savola, Suvi, primary, Iwakawa, Reika, primary, Kohno, Takashi, primary, Yokota, Jun, primary, and Esteller, Manel, primary

Published
2023
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58. Supplementary Figure 5 from KAT6B Is a Tumor Suppressor Histone H3 Lysine 23 Acetyltransferase Undergoing Genomic Loss in Small Cell Lung Cancer

Author

Simó-Riudalbas, Laia, primary, Pérez-Salvia, Montserrat, primary, Setien, Fernando, primary, Villanueva, Alberto, primary, Moutinho, Catia, primary, Martínez-Cardús, Anna, primary, Moran, Sebastian, primary, Berdasco, Maria, primary, Gomez, Antonio, primary, Vidal, Enrique, primary, Soler, Marta, primary, Heyn, Holger, primary, Vaquero, Alejandro, primary, de la Torre, Carolina, primary, Barceló-Batllori, Silvia, primary, Vidal, August, primary, Roz, Luca, primary, Pastorino, Ugo, primary, Szakszon, Katalin, primary, Borck, Guntram, primary, Moura, Conceição S., primary, Carneiro, Fátima, primary, Zondervan, Ilse, primary, Savola, Suvi, primary, Iwakawa, Reika, primary, Kohno, Takashi, primary, Yokota, Jun, primary, and Esteller, Manel, primary

Published
2023
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59. Supplementary Figure 7 from KAT6B Is a Tumor Suppressor Histone H3 Lysine 23 Acetyltransferase Undergoing Genomic Loss in Small Cell Lung Cancer

Author

Simó-Riudalbas, Laia, primary, Pérez-Salvia, Montserrat, primary, Setien, Fernando, primary, Villanueva, Alberto, primary, Moutinho, Catia, primary, Martínez-Cardús, Anna, primary, Moran, Sebastian, primary, Berdasco, Maria, primary, Gomez, Antonio, primary, Vidal, Enrique, primary, Soler, Marta, primary, Heyn, Holger, primary, Vaquero, Alejandro, primary, de la Torre, Carolina, primary, Barceló-Batllori, Silvia, primary, Vidal, August, primary, Roz, Luca, primary, Pastorino, Ugo, primary, Szakszon, Katalin, primary, Borck, Guntram, primary, Moura, Conceição S., primary, Carneiro, Fátima, primary, Zondervan, Ilse, primary, Savola, Suvi, primary, Iwakawa, Reika, primary, Kohno, Takashi, primary, Yokota, Jun, primary, and Esteller, Manel, primary

Published
2023
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60. Data from KAT6B Is a Tumor Suppressor Histone H3 Lysine 23 Acetyltransferase Undergoing Genomic Loss in Small Cell Lung Cancer

Author

Simó-Riudalbas, Laia, primary, Pérez-Salvia, Montserrat, primary, Setien, Fernando, primary, Villanueva, Alberto, primary, Moutinho, Catia, primary, Martínez-Cardús, Anna, primary, Moran, Sebastian, primary, Berdasco, Maria, primary, Gomez, Antonio, primary, Vidal, Enrique, primary, Soler, Marta, primary, Heyn, Holger, primary, Vaquero, Alejandro, primary, de la Torre, Carolina, primary, Barceló-Batllori, Silvia, primary, Vidal, August, primary, Roz, Luca, primary, Pastorino, Ugo, primary, Szakszon, Katalin, primary, Borck, Guntram, primary, Moura, Conceição S., primary, Carneiro, Fátima, primary, Zondervan, Ilse, primary, Savola, Suvi, primary, Iwakawa, Reika, primary, Kohno, Takashi, primary, Yokota, Jun, primary, and Esteller, Manel, primary

Published
2023
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61. Supplementary Figure 1 from KAT6B Is a Tumor Suppressor Histone H3 Lysine 23 Acetyltransferase Undergoing Genomic Loss in Small Cell Lung Cancer

Author

Simó-Riudalbas, Laia, primary, Pérez-Salvia, Montserrat, primary, Setien, Fernando, primary, Villanueva, Alberto, primary, Moutinho, Catia, primary, Martínez-Cardús, Anna, primary, Moran, Sebastian, primary, Berdasco, Maria, primary, Gomez, Antonio, primary, Vidal, Enrique, primary, Soler, Marta, primary, Heyn, Holger, primary, Vaquero, Alejandro, primary, de la Torre, Carolina, primary, Barceló-Batllori, Silvia, primary, Vidal, August, primary, Roz, Luca, primary, Pastorino, Ugo, primary, Szakszon, Katalin, primary, Borck, Guntram, primary, Moura, Conceição S., primary, Carneiro, Fátima, primary, Zondervan, Ilse, primary, Savola, Suvi, primary, Iwakawa, Reika, primary, Kohno, Takashi, primary, Yokota, Jun, primary, and Esteller, Manel, primary

Published
2023
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62. Data from Microenvironment-Modulated Metastatic CD133+/CXCR4+/EpCAM− Lung Cancer–Initiating Cells Sustain Tumor Dissemination and Correlate with Poor Prognosis

Author

Bertolini, Giulia, primary, D'Amico, Lucia, primary, Moro, Massimo, primary, Landoni, Elena, primary, Perego, Paola, primary, Miceli, Rosalba, primary, Gatti, Laura, primary, Andriani, Francesca, primary, Wong, Donald, primary, Caserini, Roberto, primary, Tortoreto, Monica, primary, Milione, Massimo, primary, Ferracini, Riccardo, primary, Mariani, Luigi, primary, Pastorino, Ugo, primary, Roato, Ilaria, primary, Sozzi, Gabriella, primary, and Roz, Luca, primary

Published
2023
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63. Supplementary Figure 2 from KAT6B Is a Tumor Suppressor Histone H3 Lysine 23 Acetyltransferase Undergoing Genomic Loss in Small Cell Lung Cancer

Author

Simó-Riudalbas, Laia, primary, Pérez-Salvia, Montserrat, primary, Setien, Fernando, primary, Villanueva, Alberto, primary, Moutinho, Catia, primary, Martínez-Cardús, Anna, primary, Moran, Sebastian, primary, Berdasco, Maria, primary, Gomez, Antonio, primary, Vidal, Enrique, primary, Soler, Marta, primary, Heyn, Holger, primary, Vaquero, Alejandro, primary, de la Torre, Carolina, primary, Barceló-Batllori, Silvia, primary, Vidal, August, primary, Roz, Luca, primary, Pastorino, Ugo, primary, Szakszon, Katalin, primary, Borck, Guntram, primary, Moura, Conceição S., primary, Carneiro, Fátima, primary, Zondervan, Ilse, primary, Savola, Suvi, primary, Iwakawa, Reika, primary, Kohno, Takashi, primary, Yokota, Jun, primary, and Esteller, Manel, primary

Published
2023
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64. Supplementary Table S2 from Microenvironment-Modulated Metastatic CD133+/CXCR4+/EpCAM− Lung Cancer–Initiating Cells Sustain Tumor Dissemination and Correlate with Poor Prognosis

Author

Bertolini, Giulia, primary, D'Amico, Lucia, primary, Moro, Massimo, primary, Landoni, Elena, primary, Perego, Paola, primary, Miceli, Rosalba, primary, Gatti, Laura, primary, Andriani, Francesca, primary, Wong, Donald, primary, Caserini, Roberto, primary, Tortoreto, Monica, primary, Milione, Massimo, primary, Ferracini, Riccardo, primary, Mariani, Luigi, primary, Pastorino, Ugo, primary, Roato, Ilaria, primary, Sozzi, Gabriella, primary, and Roz, Luca, primary

Published
2023
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65. Supplementary Figure 4 from KAT6B Is a Tumor Suppressor Histone H3 Lysine 23 Acetyltransferase Undergoing Genomic Loss in Small Cell Lung Cancer

Author

Simó-Riudalbas, Laia, primary, Pérez-Salvia, Montserrat, primary, Setien, Fernando, primary, Villanueva, Alberto, primary, Moutinho, Catia, primary, Martínez-Cardús, Anna, primary, Moran, Sebastian, primary, Berdasco, Maria, primary, Gomez, Antonio, primary, Vidal, Enrique, primary, Soler, Marta, primary, Heyn, Holger, primary, Vaquero, Alejandro, primary, de la Torre, Carolina, primary, Barceló-Batllori, Silvia, primary, Vidal, August, primary, Roz, Luca, primary, Pastorino, Ugo, primary, Szakszon, Katalin, primary, Borck, Guntram, primary, Moura, Conceição S., primary, Carneiro, Fátima, primary, Zondervan, Ilse, primary, Savola, Suvi, primary, Iwakawa, Reika, primary, Kohno, Takashi, primary, Yokota, Jun, primary, and Esteller, Manel, primary

Published
2023
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66. Ascl1 and OTP tumour expressions are associated with disease‐free survival in lung atypical carcinoids

Author

Centonze, Giovanni, primary, Maisonneuve, Patrick, additional, Simbolo, Michele, additional, Lagano, Vincenzo, additional, Grillo, Federica, additional, Prinzi, Natalie, additional, Pusceddu, Sara, additional, Missiato, Loretta, additional, Colantuono, Marilena, additional, Sabella, Giovanna, additional, Bercich, Luisa, additional, Mangogna, Alessandro, additional, Rolli, Luigi, additional, Grisanti, Salvatore, additional, Benvenuti, Mauro Roberto, additional, Pastorino, Ugo, additional, Roz, Luca, additional, Scarpa, Aldo, additional, Berruti, Alfredo, additional, Capella, Carlo, additional, and Milione, Massimo, additional

Published
2023
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70. sj-pdf-1-tmj-10.1177_03008916231154763 – Supplemental material for Long term outcome of complex surgical resection and reconstruction for rare thoracic cancers

Author

Pastorino, Ugo, Leuzzi, Giovanni, Sabia, Federica, Girotti, Paolo, Duranti, Leonardo, Radaelli, Stefano, Fiore, Marco, Stacchiotti, Silvia, Patrizia, Giannatempo, Salvioni, Roberto, and Gronchi, Alessandro

Subjects
Medicine
Abstract

Supplemental material, sj-pdf-1-tmj-10.1177_03008916231154763 for Long term outcome of complex surgical resection and reconstruction for rare thoracic cancers by Ugo Pastorino, Giovanni Leuzzi, Federica Sabia, Paolo Girotti, Leonardo Duranti, Stefano Radaelli, Marco Fiore, Silvia Stacchiotti, Giannatempo Patrizia, Roberto Salvioni and Alessandro Gronchi in Tumori Journal

Published
2023
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72. A Prognostic Model Including Pre- and Postsurgical Variables to Enhance Risk Stratification of Primary Mediastinal Nonseminomatous Germ Cell Tumors: The 27-Year Experience of a Referral Center

Author

Necchi, Andrea, Giannatempo, Patrizia, Lo Vullo, Salvatore, Farè, Elena, Raggi, Daniele, Marongiu, Manuela, Scanagatta, Paolo, Duranti, Leonardo, Giovannetti, Riccardo, Girelli, Lara, Nicolai, Nicola, Piva, Luigi, Biasoni, Davide, Torelli, Tullio, Catanzaro, Mario, Stagni, Silvia, Maffezzini, Massimo, Gianni, Alessandro M., Mariani, Luigi, Pastorino, Ugo, and Salvioni, Roberto

Published
2015
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73. Prognostic Factors Across Poorly Differentiated Neuroendocrine Neoplasms: a Pooled Analysis

Author

Centonze, Giovanni, primary, Maisonneuve, Patrick, additional, Prinzi, Natalie, additional, Pusceddu, Sara, additional, Albarello, Luca, additional, Pisa, Eleonora, additional, Barberis, Massimo, additional, Vanoli, Alessandro, additional, Spaggiari, Paola, additional, Bossi, Paola, additional, Cattaneo, Laura, additional, Sabella, Giovanna, additional, Solcia, Enrico, additional, La Rosa, Stefano, additional, Grillo, Federica, additional, Tagliabue, Giovanna, additional, Scarpa, Aldo, additional, Papotti, Mauro, additional, Volante, Marco, additional, Mangogna, Alessandro, additional, Del Gobbo, Alessandro, additional, Ferrero, Stefano, additional, Rolli, Luigi, additional, Roca, Elisa, additional, Bercich, Luisa, additional, Benvenuti, Mauro, additional, Messerini, Luca, additional, Inzani, Frediano, additional, Pruneri, Giancarlo, additional, Busico, Adele, additional, Perrone, Federica, additional, Tamborini, Elena, additional, Pellegrinelli, Alessio, additional, Kankava, Ketevani, additional, Berruti, Alfredo, additional, Pastorino, Ugo, additional, Fazio, Nicola, additional, Sessa, Fausto, additional, Capella, Carlo, additional, Rindi, Guido, additional, and Milione, Massimo, additional

Published
2022
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74. Lung carcinoid tumours: histology and Ki‐67, the eternal rivalry

Author

Centonze, Giovanni, primary, Maisonneuve, Patrick, additional, Simbolo, Michele, additional, Lagano, Vincenzo, additional, Grillo, Federica, additional, Fabbri, Alessandra, additional, Prinzi, Natalie, additional, Garzone, Giovanna, additional, Filugelli, Martina, additional, Pardo, Carlotta, additional, Mietta, Alessia, additional, Pusceddu, Sara, additional, Sabella, Giovanna, additional, Bercich, Luisa, additional, Mangogna, Alessandro, additional, Rolli, Luigi, additional, Grisanti, Salvatore, additional, Benvenuti, Mauro Roberto, additional, Pastorino, Ugo, additional, Roz, Luca, additional, Scarpa, Aldo, additional, Berruti, Alfredo, additional, Capella, Carlo, additional, and Milione, Massimo, additional

Published
2022
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76. Thymus neuroendocrine tumors with CTNNB1 gene mutations, disarrayed ß-catenin expression, and dual intra-tumor Ki-67 labeling index compartmentalization challenge the concept of secondary high-grade neuroendocrine tumor: a paradigm shift

Author

Fabbri, Alessandra, Cossa, Mara, Sonzogni, Angelica, Bidoli, Paolo, Canova, Stefania, Cortinovis, Diego, Abbate, Maria Ida, Calabrese, Fiorella, Nannini, Nazarena, Lunardi, Francesca, Rossi, Giulio, La Rosa, Stefano, Capella, Carlo, Tamborini, Elena, Perrone, Federica, Busico, Adele, Capone, Iolanda, Valeri, Barbara, Pastorino, Ugo, Albini, Adriana, and Pelosi, Giuseppe

Published
2017
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78. Combined Large Cell Neuroendocrine Carcinomas of the Lung: Integrative Molecular Analysis Identifies Subtypes with Potential Therapeutic Implications

Author

Simbolo, Michele, primary, Centonze, Giovanni, additional, Giudice, Luca, additional, Grillo, Federica, additional, Maisonneuve, Patrick, additional, Gkountakos, Anastasios, additional, Ciaparrone, Chiara, additional, Cattaneo, Laura, additional, Sabella, Giovanna, additional, Giugno, Rosalba, additional, Bossi, Paola, additional, Spaggiari, Paola, additional, Del Gobbo, Alessandro, additional, Ferrero, Stefano, additional, Mastracci, Luca, additional, Fabbri, Alessandra, additional, Filugelli, Martina, additional, Garzone, Giovanna, additional, Prinzi, Natalie, additional, Pusceddu, Sara, additional, Testi, Adele, additional, Monti, Valentina, additional, Rolli, Luigi, additional, Mangogna, Alessandro, additional, Bercich, Luisa, additional, Benvenuti, Mauro Roberto, additional, Bria, Emilio, additional, Pilotto, Sara, additional, Berruti, Alfredo, additional, Pastorino, Ugo, additional, Capella, Carlo, additional, Infante, Maurizio, additional, Milella, Michele, additional, Scarpa, Aldo, additional, and Milione, Massimo, additional

Published
2022
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80. Increased serum levels of KiSS1-derived peptides in non-small cell lung cancer patient liquid biopsies and biological relevance

Author

Gatti, Laura, primary, Rolli, Luigi, additional, Corno, Cristina, additional, Carenini, Nives, additional, Corna, Elisabetta, additional, Ciusani, Emilio, additional, Frigerio, Simona, additional, Pogliani, Simona, additional, Guarino, Carmela, additional, Ravagnani, Ferdinando, additional, Pastorino, Ugo, additional, Sozzi, Gabriella, additional, Macciotta, Alessandra, additional, Verderio, Paolo, additional, Ciniselli, Chiara M., additional, and Perego, Paola, additional

Published
2022
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88. Deciphering intra-tumor heterogeneity of lung adenocarcinoma confirms that dominant, branching, and private gene mutations occur within individual tumor nodules

Author

Pelosi, Giuseppe, Pellegrinelli, Alessio, Fabbri, Alessandra, Tamborini, Elena, Perrone, Federica, Settanni, Giulio, Busico, Adele, Picciani, Benedetta, Testi, Maria Adele, Militti, Lucia, Maisonneuve, Patrick, Valeri, Barbara, Sonzogni, Angelica, Proto, Claudia, Garassino, Marina, De Braud, Filippo, and Pastorino, Ugo

Published
2016
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89. Abstract 1539: LKB1 down-modulation by miR-17 biologically and clinically mirrors LKB1-mutated NSCLC

Author

Borzi, Cristina, primary, Ganzinelli, Monica, additional, Caiola, Elisa, additional, Colombo, Marika, additional, Centonze, Giovanni, additional, Boeri, Mattia, additional, Caleca, Laura, additional, Pastorino, Ugo, additional, Marabese, Mirko, additional, Milione, Massimo, additional, Broggini, Massimo, additional, Garassino, Marina C., additional, Sozzi, Gabriella, additional, and Moro, Massimo, additional

Published
2022
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92. Phase III study with atezolizumab versus placebo in patients with malignant pleural mesothelioma after pleurectomy/decortication (AtezoMeso study).

Author

Pagano, Maria, primary, Alloisio, Marco, additional, Cappuzzo, Federico, additional, Facciolo, Francesco, additional, Bironzo, Paolo, additional, Pastorino, Ugo, additional, Rea, Federico, additional, Santoro, Armando, additional, Zanelli, Francesca, additional, Alberti, Giulia, additional, Bonelli, Candida, additional, Gervasi, Erika, additional, and Pinto, Carmine, additional

Published
2022
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93. Outcome of complex surgical resection and reconstruction for rare thoracic cancers: the clinical value of a predictive score

Author

Pastorino, Ugo, primary, Leuzzi, Giovanni, additional, Sabia, Federica, additional, Girotti, Paolo, additional, Duranti, Leonardo, additional, Radaelli, Stefano, additional, Fiore, Marco, additional, Stacchiotti, Silvia, additional, Patrizia, Giannatempo, additional, Salvioni, Roberto, additional, and Gronchi, Alessandro, additional

Published
2022
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97. Lung carcinoid tumours: histology and Ki-67, the eternal rivalry.

Author

Centonze, Giovanni, Maisonneuve, Patrick, Simbolo, Michele, Lagano, Vincenzo, Grillo, Federica, Fabbri, Alessandra, Prinzi, Natalie, Garzone, Giovanna, Filugelli, Martina, Pardo, Carlotta, Mietta, Alessia, Pusceddu, Sara, Sabella, Giovanna, Bercich, Luisa, Mangogna, Alessandro, Rolli, Luigi, Grisanti, Salvatore, Benvenuti, Mauro Roberto, Pastorino, Ugo, and Roz, Luca

Subjects
KI-67 antigen, CARCINOID, NEUROENDOCRINE tumors, HISTOLOGY, TUMORS, LUNGS
Abstract

WHO classification of Thoracic Tumours defines lung carcinoid tumours (LCTs) as well-differentiated neuroendocrine neoplasms (NENs) classified in low grade typical (TC) and intermediate grade atypical carcinoids (AC). Limited data exist concerning protein expression and morphologic factors able to predict disease aggressiveness. Though Ki-67 has proved to be a powerful diagnostic and prognostic factor for Gastro-entero-pancreatic NENs, its role in lung NENs is still debated. A retrospective series of 370 LCT from two oncology centers was centrally reviewed. Morphology and immunohistochemical markers (Ki-67, TTF-1, CD44, OTP, SSTR-2A, Ascl1, and p53) were studied and correlated with Overall Survival (OS), Cancer-specific survival (CSS) and Disease-free survival (DFS). Carcinoid histology was confirmed in 355 patients: 297 (83.7%) TC and 58 (16.3%) AC. Ki-67 at 3% was the best value in predicting DFS. Ki67 ≥ 3% tumours were significantly associated with AC histology, stage III-IV, smoking, vascular invasion, tumour spread through air spaces OTP negativity, and TTF-1, Ascl1 and p53 positivity. After adjustment for center and period of diagnosis, both Ki-67 (≥3 versus <3) and histology (AC versus TC) alone significantly added prognostic information to OS and CSS multivariable model with age, stage and OTP; addition of both variables did not provide further prognostic information. Conversely, an improved significance of the DFS prediction model at multivariate analysis was seen by adding Ki-67 (≥3 versus <3, P adj = 0.01) to TC and AC histological distinction, age, lymph node involvement, residual tumour and OTP. Ki-67 ≥ 3% plays a potentially pivotal role in LCT prognosis, irrespective of histological grade. [ABSTRACT FROM AUTHOR]

Published
2023
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99. Single-Cell Phenotypic and Molecular Characterization of Circulating Tumor Cells Isolated from Cryopreserved Peripheral Blood Mononuclear Cells of Patients with Lung Cancer and Sarcoma

Author

Vismara, Marta, primary, Reduzzi, Carolina, additional, Silvestri, Marco, additional, Murianni, Fabio, additional, Lo Russo, Giuseppe, additional, Fortunato, Orazio, additional, Motta, Rosita, additional, Lanzoni, Davide, additional, Giovinazzo, Francesca, additional, Miodini, Patrizia, additional, Pasquali, Sandro, additional, Suatoni, Paola, additional, Pastorino, Ugo, additional, Roz, Luca, additional, Sozzi, Gabriella, additional, Cappelletti, Vera, additional, and Bertolini, Giulia, additional

Published
2022
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100. MiR-486-5p Targets CD133+ Lung Cancer Stem Cells through the p85/AKT Pathway

Author

Moro, Massimo, primary, Fortunato, Orazio, additional, Bertolini, Giulia, additional, Mensah, Mavis, additional, Borzi, Cristina, additional, Centonze, Giovanni, additional, Andriani, Francesca, additional, Di Paolo, Daniela, additional, Perri, Patrizia, additional, Ponzoni, Mirco, additional, Pastorino, Ugo, additional, Sozzi, Gabriella, additional, and Boeri, Mattia, additional

Published
2022
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