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Background: Treatment-resistant schizophrenia (TRS) is one of the most disabling forms of schizophrenia. The Indian population being different in its sociodemographic factors, clinical profiles, and family structures, the experience of the efficacy of clozapine here is insufficient. Aim: The aim of the study is to explore the efficacy of clozapine in TRS over 3 months of drug use. Materials and Methods: It was an open-label interventional 12-week follow-up study, with 30 consenting adults with TRS determined as per modified Conley and Kelly's criteria of treatment resistance. The patient's sociodemographic and clinical details were recorded. Oral clozapine was initiated with gradual up-titration after preclozapine workup. The Positive and Negative Syndrome Scale (PANSS) score was assessed at baseline and reviewed at 4 weekly intervals. Results: By the end of 12 weeks, on an average dose of 494 ± 113.83 mg/day, 36.67% of patients reported 25%-50% improvement in PANSS score. The maximum improvement was seen in the positive symptoms subscale followed by the general and negative symptoms subscale. Conclusion: This study enlightens the dosage differences and efficacy of clozapine in the management of TRS in the Indian population. [ABSTRACT FROM AUTHOR]

An E-Consumer differs from a regular consumer in many aspects. There are many additional parameters involved in online transactions vis-a-vis offline ones. For example, the physical evidence, one of the Ps in the marketing mix, is very different for a brick-and-mortar consumer and an E-Consumer. An E-Consumer gets affected by the design and user-friendliness of the website, online customer service available, etc. A company’s value chain needs to be flexible enough to respond to the needs of the online consumer by incorporating advancements in technology. This paper begins with the development of a conceptual framework that explores dimensions of marketing, artificial intelligence and value chain affecting the company. The model is further explored to enlist identified variables, and identify their contextual relationship using Nominal Group Technique. Interpretive Structural Modelling and Matrice d’impacts croisés multiplication appliquée á un classment analysis have been adopted to understand the complex interrelationships amongst identified variables and to create a simpler hierarchical structure to understand the effect of E-Consumer behaviour on a company’s value chain. [ABSTRACT FROM AUTHOR]

Background: Health insurance (HI) is one of the ways by which Out-Of-Pocket Expenditure can be reduced. However, only 15% of the Indian population purchased some kind of HI. Thus, we aimed to study the awareness, enrollment, and reasons for non-enrollment of HI among patients attending public and private hospitals. Materials and methods: A hospital-based cross-sectional study was conducted among 403 patients from both public and private hospitals attached to a medical college in Mangalore. Patients were interviewed using a pre-tested, semi-structured questionnaire after obtaining a written informed consent. The data were entered and analyzed using SPSS 25. Results: The study shows that 74.4% of the patients were aware of HI. The main sources of information were friends and Newspaper.71% had purchased a HI. The foremost reason to purchase a HI was to cover medical expenditure (84.6%), chiefly the surgical expenses. The most cited reason for non-enrollment in HI schemes was lack of awareness. Conclusion: The awareness regarding HI was found to be high. However, not all who were aware had a HI. [ABSTRACT FROM AUTHOR]

For anyone involved in E-business and connected to the field of corporate finance, understanding the mechanism of an online business and its valuation is an indispensable requisite. This is not only because of the importance of valuation in acquisitions and mergers but also because the process of valuing a business and its units helps identify sources of economic value creation and destruction within the company. Similarly, this value creation is affected by many a factors which are non-financial in nature and do not get incorporated while valuation. The firm, further goes through many a common mistake too and these are the result of relying upon the traditional practices and the methods. Hence, need is to find out such factors and problematic contents that distorts the valuation and misinterpretation of the business and its financial position. The vigilance and expertise along with experience are the characteristics required to be with the financial analyst so as to avoid such blunders in financial analysis. [ABSTRACT FROM AUTHOR]

Consumer responsiveness is highly dynamic and volatile in nature. In past studies, there have been numerous variables identified however soon it was understood that the final implication of communication on responsiveness is consequence of interaction and connection between these elements. Marketers in present world have been facing challenges in terms of understanding the relationship between these elements. This study will focus, explore and explain how the marketing of the product can be made more effective and efficient. This study becomes more important because it categorise the critical factors thus making things easier to plan for better marketing of the product. This study explains the sequential approach of marketing with relevance of each of the factor. This study will quantify level of exposure of advertisement that compel consumer to buy product. The methodology focuses on ISM modelling to identify and summarizing relationship between various specific variables, defining the problem. This technique is best suited to deal with the complex situation and finding out their solution. In the present study, main focus would be on the different factors that are responsible for change in responsiveness of customer towards any advertisement. After review of various studies and customer opinion on the survey various factors will be identified and ISM modelling is done to predict relationship between various variables. [ABSTRACT FROM AUTHOR]

Cloud Computing is an emerging concept which envisage the usage of internet for deploying and delivering business application as pay per use model. Cloud computing is attractive for business owners because it eliminates the need for users to set up ahead for provisioning, and permits enterprises to begin from the little and increase resources only when an increase in demand. However, despite the actual fact that cloud computing offers vast opportunities to the IT business, the event of cloud computing technology is presently at its infancy, with several problems still to be addressed. If cloud computing is to realize its potential, there has to be a transparent understanding of the varied problems concerned, each from the views of the suppliers and therefore the shoppers of the technology. There is associated equally pressing want for understanding the business-related problems regarding implementation of cloud computing. [ABSTRACT FROM AUTHOR]