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459 results on '"Pan Yanglin"'

51. Endoscopic Papillary Large Balloon Dilation Reduces Further Recurrence in Patients With Recurrent Common Bile Duct Stones: A Randomized Controlled Trial

Author

Wang, Xu, primary, Wang, Xiangping, additional, Sun, Hao, additional, Ren, Gui, additional, Wang, Biaoluo, additional, Liang, Shuhui, additional, Zhang, Linhui, additional, Kang, Xiaoyu, additional, Tao, Qin, additional, Guo, Xuegang, additional, Luo, Hui, additional, and Pan, Yanglin, additional

Published
2022
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53. Low-dose of magnesium sulfate solution was not inferior to standard regime of polyethylene glycol for bowel preparation in elderly patients: a randomized, controlled study.

Author

Ge, Fulin, Kang, Xiaoyu, Wang, Zeyu, Zhu, Hailan, Liao, Liang, Wang, Ming, Jia, Jianjun, Lou, Lijun, Guo, Xuegang, Pan, Yanglin, and Wan, Jun

Subjects
OLDER patients, MAGNESIUM sulfate, POLYETHYLENE glycol, ADENOMA, ABDOMINAL pain
Abstract

Large polyethylene glycol (PEG) is a standard regimen for bowel preparation. However, elderly patients suffered from adverse events. This study was to compare the efficacy and safety of oral magnesium sulfate solution (MSS) vs standard PEG in elderly patients undergoing colonoscopy. Elderly patients aged 60–90 years, from two endoscopic centers, were enrolled in China. Patients were randomized to take a low dose of MSS or a standard PEG regime in a split-dose regime. The primary endpoint was the proportion of patients with adequate bowel preparation, which was defined as the total Boston Bowel Preparation Scale (BBPS) ≥6 and each segmental BBPS was ≥2. Secondary outcomes included adenoma detection rate (ADR), safety, adverse events, cecal intubation rate, willingness to repeat BP, and so on. 1174 elderly patients were randomly allocated to the MSS group (n = 588) or the standard group (n = 586). Adequate BP was achieved in 94.0% of patients in the MSS group and 92.5% in the control (p =.287). ADR was also comparable between the two groups (43.0% and 39.9%, p =.282). Compared with the standard group, MSS group reported less abdominal discomfort (1.7% vs 6.0%), less nausea (13.6% vs 21.0%) and vomiting (1.2% vs 4.2%). The change in serum potassium levels after preparation in the standard group was significantly lower than that in the MSS group (−0.19 ± 0.08 vs −0.41 ± 0.11, p =.037). Low dose of MSS was not inferior to the standard PEG regime in terms of bowel preparation quality for elderly patients. Low-dose MSS offered fewer adverse events and better tolerability. It is a preferable choice for the elderly to undergo bowel preparation for colonoscopy. NCT 04948567 [ABSTRACT FROM AUTHOR]

Published
2023
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61. Water-assisted colonoscopy: an international modified Delphi review on definitions and practice recommendations

Author

Cadoni, Sergio, primary, Ishaq, Sauid, additional, Hassan, Cesare, additional, Falt, Přemysl, additional, Fuccio, Lorenzo, additional, Siau, Keith, additional, Leung, Joseph W., additional, Anderson, John, additional, Binmoeller, Kenneth F., additional, Radaelli, Franco, additional, Rutter, Matt D., additional, Sugimoto, Shinya, additional, Muhammad, Humayun, additional, Bhandari, Pradeep, additional, Draganov, Peter V., additional, de Groen, Piet, additional, Wang, Andrew Y., additional, Yen, Andrew W., additional, Hamerski, Chris, additional, Thorlacius, Henrik, additional, Neumann, Helmut, additional, Ramirez, Francisco, additional, Mulder, Chris J.J., additional, Albéniz, Eduardo, additional, Amato, Arnaldo, additional, Arai, Makoto, additional, Bak, Adrian, additional, Barret, Maximilien, additional, Bayupurnama, Putut, additional, Cheung, Ramsey, additional, Ching, Hey-Long, additional, Cohen, Hartley, additional, Dolwani, Sunil, additional, Friedland, Shai, additional, Harada, Hideaki, additional, Hsieh, Yu-Hsi, additional, Hayee, Bu, additional, Kuwai, Toshio, additional, Lorenzo-Zúñiga, Vicente, additional, Liggi, Mauro, additional, Mizukami, Takeshi, additional, Mura, Donatella, additional, Nylander, David, additional, Olafsson, Snorri, additional, Paggi, Silvia, additional, Pan, Yanglin, additional, Parra-Blanco, Adolfo, additional, Ransford, Rupert, additional, Rodriguez-Sanchez, Joaquìn, additional, Senturk, Hakan, additional, Suzuki, Noriko, additional, Tseng, Chih-Wei, additional, Uchima, Hugo, additional, Uedo, Noriya, additional, and Leung, Felix W., additional

Published
2021
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70. Combination prevention of post‐endoscopic retrograde cholangiopancreatography pancreatitis in patients undergoing double‐guidewire assisted biliary cannulation: A case–control study with propensity score matching

Author

Wang, Xu, primary, Luo, Hui, additional, Luo, Bing, additional, Ren, Gui, additional, Liang, Shuhui, additional, Wang, Xiangping, additional, Tao, Qin, additional, Zhang, Linhui, additional, Kang, Xiaoyu, additional, Guo, Xuegang, additional, and Pan, Yanglin, additional

Published
2021
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73. Advances in endoscopic retrograde cholangiopancreatography

Author

WANG Xiangping, PAN Yanglin, and GUO Xuegang

Subjects
cholangiopancreatography, surgical procedures, operative, per-oral cholangioscopy, pancreatitis, biliary stricture, precut sphincterotomy, lcsh:Diseases of the digestive system. Gastroenterology, lcsh:RC799-869, digestive system, endoscopic retrograde
Abstract

Endoscopic retrograde cholangiopancreatography (ERCP) is a well-established advanced endoscopic technique for the diagnosis and treatment of pancreatobiliary diseases. New advances have been made in the treatment concept and techniques of ERCP in recent years. This article elaborates on the recent advances in ERCP, including the application of pancreatic duct stent, non-steroidal anti-inflammatory drugs, and aggressive hydration to prevent postoperative pancreatitis, covered metal stent for the treatment of benign bile duct stenosis, intraluminal radiofrequency ablation for malignant bile duct stenosis, extracorporeal shockwave lithotripsy and covered metal stent for the treatment of chronic pancreatitis, peroral choledochoscopy for qualitative diagnosis of bile duct stenosis and huge refractory stones, definition of difficult intubation, timing of pre-cut technique, and ERCP after gastrointestinal reconstruction.

Published
2018

74. Superiority of a Procedure-Related Model for Predicting Inadequate Bowel Preparation in Patients Undergoing Colonoscopy: A Multicenter Prospective Study

Author

Chen, Long, primary, Zhang, Linhui, additional, Ren, Gui, additional, Luo, Hui, additional, Wang, Limei, additional, Zhao, Jianghai, additional, Zhang, Rongchun, additional, Ni, Zhi, additional, Zhang, Xiaoying, additional, Qin, Bin, additional, Zhang, Mingxin, additional, Liu, Sha, additional, Liu, Wenjuan, additional, Tang, Ming, additional, Zhang, Li, additional, Zeng, Wei, additional, Liang, Yi, additional, Rang, Wenbin, additional, Jing, Haifeng, additional, Dong, Shengxiao, additional, Kang, Xiaoyu, additional, and Pan, Yanglin, additional

Published
2021
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75. Difficult biliary cannulation in ERCP procedures with or without trainee involvement: a comparative study.

Author

Wang, Xu, Luo, Hui, Tao, Qin, Ren, Gui, Wang, Xiangping, Liang, Shuhui, Zhang, Linhui, Chen, Long, Shi, Xin, Guo, Xuegang, and Pan, Yanglin

Subjects
PANCREAS, ENDOSCOPIC retrograde cholangiopancreatography, RESEARCH funding, PANCREATITIS, CATHETERIZATION, ENDOSCOPIC gastrointestinal surgery
Abstract

Background: The 5-5-1 criteria (> 5 minutes - 5 cannulation attempts - 1 unintended pancreas duct cannulation) were proposed by the European Society of Gastrointestinal Endoscopy to define difficult biliary cannulation. However, the criteria may be inappropriate for trainee-involved procedures. We developed criteria for difficult cannulation in trainee-involved procedures.Methods: Patients undergoing biliary cannulation with or without trainee involvement were eligible. Procedures that might be too easy (e. g. fistula) or too difficult (e. g. altered anatomy) were excluded. The primary outcome was difficult cannulation, defined as cannulation time, attempts, or inadvertent pancreatic duct (PD) cannulation exceeding the 75 % percentile of each variable. Propensity score matching (PSM) analysis was used.Results: After PSM, there were 1596 patients in each group. Trainee-involved procedures had longer median (interquartile range [IQR]) cannulation time (7.5 [2.2-15.3] vs. 2.0 [0.6-5.2] minutes), and more attempts (5 [2-10] vs. 2 [1-4]) and inadvertent PD cannulation (0 [0-2] vs. 0 [0-1]) vs. procedures without trainee involvement (all P < 0.001). The 15-10-2 criteria for difficult cannulation were proposed for trainee-involved cannulation and the 5-5-1 criteria were nearly confirmed for cannulation without trainee involvement. The proportions of difficult cannulation using these respective criteria were 35.5 % (95 % confidence interval [CI] 33.2 %-37.9 %) and 31.8 % (95 %CI 29.5 %-34.2 %), respectively (odds ratio 1.18 [95 %CI 1.02-1.37]). Incidences of post-ERCP pancreatitis following difficult cannulation were comparable (7.8 % [95 %CI 5.7 %-10.3 %] vs. 9.8 % [95 %CI 7.4 %-12.8 %], respectively).Conclusion: By using the 75 % percentiles as cutoffs, the proposed 15-10-2 criteria for difficult cannulation could be appropriate in trainee-involved procedures. [ABSTRACT FROM AUTHOR]

Published
2022
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76. Water exchange-assisted versus carbon dioxide-insufflated single-balloon enteroscopy: a randomized controlled trial.

Author

Liu, Shaopeng, Dong, Tao, Shi, Yupeng, Luo, Hui, Xue, Xianmin, Zhu, Yijin, Wang, Xiangping, Wang, Biaoluo, Liang, Shuhui, Pan, Yanglin, Guo, Xuegang, and Wu, Kaichun

Subjects
RANDOMIZED controlled trials, ENTEROSCOPY, CARBON dioxide, GEOLOGICAL carbon sequestration, INTESTINAL disease treatment, INTESTINAL disease diagnosis, RESEARCH, WATER, EVALUATION research, COMPARATIVE studies, INTESTINAL diseases, RESEARCH funding, ENDOSCOPIC gastrointestinal surgery, STATISTICAL sampling
Abstract

Background: Single-balloon enteroscopy (SBE) is a valuable but difficult modality for the diagnosis and treatment of small-bowel disease. The water exchange method has the advantage of facilitating intubation during colonoscopy. Here, we evaluated the effects of water exchange on procedure-related variables related to SBE.Methods: This randomized controlled trial was conducted in a tertiary-care referral center in China. Patients due for attempted total enteroscopy were randomly allocated to undergo water exchange-assisted (water exchange group) or carbon dioxide-insufflated enteroscopy (CO2 group). All patients were planned to undergo both anterograde and retrograde procedures. The primary outcome was the total enteroscopy rate. Secondary outcomes included the maximal insertion depth, positive findings, procedural time, and adverse events.Results: In total, 110 patients were enrolled, with 55 in each group. Baseline characteristics between the two groups were comparable. Total enteroscopy was achieved in 58.2 % (32/55) of the water exchange group and 36.4 % (20/55) of the control group (P = 0.02). The mean (standard deviation) estimated intubation depth was 521.2 (101.4) cm in the water exchange group and 481.6 (95.2) cm in the CO2 group (P = 0.04). The insertion time was prolonged in the water exchange group compared with the CO2 group (178.9 [45.1] minutes vs. 154.2 [27.6] minutes; P < 0.001). Endoscopic findings and adverse events were comparable between the two groups.Conclusions: The water exchange method improved the total enteroscopy rate and increased the intubation depth during SBE. The use of water exchange did not increase the complications of enteroscopy. [ABSTRACT FROM AUTHOR]

Published
2022
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79. Relationship between papilla‐related variables and post endoscopic retrograde cholangiopancreatography pancreatitis: A multicenter, prospective study

Author

Wang, Xiangping, primary, Zhao, Jianghai, additional, Wang, Limei, additional, Ning, Bo, additional, Zeng, Wei, additional, Tao, Qin, additional, Ren, Gui, additional, Liang, Shuhui, additional, Luo, Hui, additional, Wang, Biaoluo, additional, Farrell, James J., additional, Pan, Yanglin, additional, Guo, Xuegang, additional, and Wu, Kaichun, additional

Published
2020
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80. Learning curve of double‐guidewire technique by trainees during hands‐on endoscopic retrograde cholangiopancreatography training

Author

Wang, Xiangping, primary, Ren, Gui, additional, Xi, Yibin, additional, Luo, Hui, additional, Liang, Shuhui, additional, Wang, Biaoluo, additional, Tao, Qin, additional, Luo, Bing, additional, Qin, Qian, additional, Farrell, James J, additional, Guo, Xuegang, additional, Wu, Kaichun, additional, and Pan, Yanglin, additional

Published
2020
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88. Risk Factors Associated with Inadequate Bowel Preparation in Patients with Functional Constipation

Author

Guo, Xiaoyang, primary, Shi, Xin, additional, Kang, Xiaoyu, additional, Luo, Hui, additional, Wang, Xiangping, additional, Jia, Hui, additional, Tao, Qin, additional, Wang, Jingjie, additional, Zhang, Mingxin, additional, Wang, Jinhai, additional, Lu, Xiaolan, additional, Ma, Shiyang, additional, Lin, Tao, additional, Jing, Yujie, additional, Pan, Yanglin, additional, Guo, Xuegang, additional, and Fan, Daiming, additional

Published
2019
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90. Effect of cap-assisted esophagogastroduodenoscopy on examination of the major duodenal papilla: a noninferior, randomized controlled trial

Author

Shi, Xin, additional, Luo, Hui, additional, Ning, Bo, additional, Wang, Xiangping, additional, Tao, Qin, additional, Liang, Shuhui, additional, Zhang, Rongchun, additional, Chen, Jie, additional, Luo, Bing, additional, Yao, Shaowei, additional, Pan, Yanglin, additional, Guo, Xuegang, additional, and Fan, Daiming, additional

Published
2019
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99. Same-Day Single Dose of 2 Liter Polyethylene Glycol is Not Inferior to The Standard Bowel Preparation Regimen in Low-Risk Patients: A Randomized, Controlled Trial

Author

Kang, Xiaoyu, primary, Zhao, Lina, additional, Zhu, Zhiyong, additional, Leung, Felix, additional, Wang, Limei, additional, Wang, Xiangping, additional, Luo, Hui, additional, Zhang, Linhui, additional, Dong, Tao, additional, Li, Pingying, additional, Chen, Zhangqin, additional, Ren, Gui, additional, Jia, Hui, additional, Guo, Xiaoyang, additional, Pan, Yanglin, additional, Guo, Xuegang, additional, and Fan, Daiming, additional

Published
2018
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100. The inhibitory effect of p75 neurotrophin receptor on growth of human hepatocellular carcinoma cells

Author

He Yuanlong, Fan Daiming, Song Jialin, Zhang Xiaoyin, Song Jiugang, Pan Yanglin, Xie Huahong, Jin Haifeng, Wu Kaichun, Yan Li, Ding Jie, and Liu Jie

Subjects
Cancer Research, Carcinoma, Hepatocellular, Cell cycle checkpoint, Cyclin E, Cyclin A, Down-Regulation, Biology, Receptor, Nerve Growth Factor, Cyclin D1, Cell Line, Tumor, medicine, Humans, Genes, Tumor Suppressor, RNA, Small Interfering, Cells, Cultured, Cell Proliferation, Liver cell, Cell Cycle, Liver Neoplasms, Cell cycle, medicine.disease, Liver, Oncology, Hepatocellular carcinoma, Immunology, Cancer research, biology.protein, sense organs, A431 cells
Abstract

p75 neurotrophin receptor (p75NTR), a member of the TNF receptor superfamily, is a focus for study at present. Up to now, its role and functions in hepatocellular carcinoma were not fully elucidated. In this study, we investigated the expression of p75NTR in hepatocellular carcinoma and the impact of its alteration on tumor growth. We found that the expression of p75NTR was decreased significantly in 158 cases of hepatocellular carcinoma tissues as compared with their adjacent noncancerous counterparts, and its expression was also significantly decreased in various human hepatocellular carcinoma cell lines. Down-regulating p75NTR by specific siRNA promoted the growth of normal liver cell lines, whereas up-regulating p75NTR inhibited the growth of hepatocellular carcinoma cell lines in vitro and caused dramatic attenuation of tumor growth in vivo by induction of cell cycle arrest. Furthermore, we found that up-regulating p75NTR could down-regulate the expression of cyclin A, cyclin D1, cyclin E, cdk2, p-Rb and PCNA, but up-regulate the expression of Rb. Conversely, the results were inverse when p75NTR was down-regulated by specific siRNA. Therefore, we provided the evidence that p75NTR was a potential tumor suppressor and might be used as a therapeutic target for hepatocellular carcinoma.

Published
2008

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