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9,150 results on '"P. Imbert"'

53. EANM perspectives for CZT SPECT in brain applications

Author

Verger, Antoine, Cecchin, Diego, Guedj, Eric, Albert, Nathalie L, Brendel, Matthias, Fraioli, Francesco, Tolboom, Nelleke, Traub-Weidinger, Tatjana, Yakushev, Igor, Van Weehaeghe, Donatienne, Fernandez, Pablo Aguiar, Garibotto, Valentina, and Imbert, Laetitia

Published
2024
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55. Multi-Calorimetry in Light-based Neutrino Detectors

Author

Cabrera, Anatael, Han, Yang, Calvez, Steven, Chauveau, Emmanuel, Chen, Hanyi, de Kerret, Hervé, Dusini, Stefano, Grassi, Marco, Imbert, Leonard, Li, Jiajun, Mandujano, Roberto Carlos, Navas-Nicolás, Diana, Nunokawa, Hiroshi, Obolensky, Michel, Ochoa-Ricoux, Juan Pedro, Pronost, Guillaume, Viaud, Benoit, and Yermia, Frédéric

Subjects
High Energy Physics - Experiment, Physics - Instrumentation and Detectors
Abstract

Neutrino detectors are among the largest photon detection instruments, built to capture scarce photons upon energy deposition. Many discoveries in neutrino physics, including the neutrino itself, are inseparable from the advances in photon detection technology, particularly in photo-sensors and readout electronics, to yield ever higher precision and richer detection information. The measurement of the energy of neutrinos, referred to as calorimetry, can be achieved in two distinct approaches: photon-counting, where single-photon can be counted digitally, and photon-integration, where multi-photons are aggregated and estimated via analogue signals. The energy is pursued today to reach permille level systematics control precision in ever-vast volumes, exemplified by experiments like JUNO. The unprecedented precision brings to the foreground the systematics due to calorimetric response entanglements in energy, position and time that were negligible in the past, thus driving further innovation in calorimetry. This publication describes a novel articulation that detectors can be endowed with multiple photon detection systems. This multi-calorimetry approach opens the notion of dual-calorimetry detector, consisting of both photon-counting and photon-integration systems, as a cost-effective evolution from the single calorimetry setups used over several decades for most experiments so far. The dual-calorimetry design exploits unique response synergies between photon-counting and photon-integration systems, including correlations and cancellations in calorimetric responses, to maximise the mitigation of response entanglements, thereby yielding permille-level high-precision calorimetry.

Published
2023
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56. Partial regularity in time for the space-homogeneous Boltzmann equation with very soft potentials

Author

Golse, François, Imbert, Cyril, and Silvestre, Luis

Subjects
Mathematics - Analysis of PDEs
Abstract

We prove that the set of singular times for weak solutions of the homogeneous Boltzmann equation with very soft potentials constructed as in Villani (1998) has Hausdorff dimension at most $\frac{|\gamma+2s|}{2s}$ with $\gamma \in [-4s,-2s)$ and $s \in (0,1)$.

Published
2023

57. JUNO sensitivity to invisible decay modes of neutrons

Author

Abusleme, Angel, Adam, Thomas, Adamowicz, Kai, Ahmad, Shakeel, Ahmed, Rizwan, Aiello, Sebastiano, An, Fengpeng, An, Qi, Andronico, Giuseppe, Anfimov, Nikolay, Antonelli, Vito, Antoshkina, Tatiana, de André, João Pedro Athayde Marcondes, Auguste, Didier, Bai, Weidong, Balashov, Nikita, Baldini, Wander, Barresi, Andrea, Basilico, Davide, Baussan, Eric, Bellato, Marco, Beretta, Marco, Bergnoli, Antonio, Bick, Daniel, Bieger, Lukas, Biktemerova, Svetlana, Birkenfeld, Thilo, Blake, Iwan, Blyth, Simon, Bolshakova, Anastasia, Bongrand, Mathieu, Breton, Dominique, Brigatti, Augusto, Brugnera, Riccardo, Bruno, Riccardo, Budano, Antonio, Busto, Jose, Cabrera, Anatael, Caccianiga, Barbara, Cai, Hao, Cai, Xiao, Cai, Yanke, Cai, Zhiyan, Callier, Stéphane, Calvez, Steven, Cammi, Antonio, Campeny, Agustin, Cao, Chuanya, Cao, Guofu, Cao, Jun, Caruso, Rossella, Cerna, Cédric, Cerrone, Vanessa, Chang, Jinfan, Chang, Yun, Chatrabhuti, Auttakit, Chen, Chao, Chen, Guoming, Chen, Pingping, Chen, Shaomin, Chen, Xin, Chen, Yiming, Chen, Yixue, Chen, Yu, Chen, Zelin, Chen, Zhangming, Chen, Zhiyuan, Chen, Zikang, Cheng, Jie, Cheng, Yaping, Cheng, Yu Chin, Chepurnov, Alexander, Chetverikov, Alexey, Chiesa, Davide, Chimenti, Pietro, Chin, Yen-Ting, Chou, Po-Lin, Chu, Ziliang, Chukanov, Artem, Claverie, Gérard, Clementi, Catia, Clerbaux, Barbara, Molla, Marta Colomer, Lorenzo, Selma Conforti Di, Coppi, Alberto, Corti, Daniele, Csakli, Simon, Cui, Chenyang, Corso, Flavio Dal, Dalager, Olivia, Datta, Jaydeep, De La Taille, Christophe, Deng, Zhi, Deng, Ziyan, Ding, Xiaoyu, Ding, Xuefeng, Ding, Yayun, Dirgantara, Bayu, Dittrich, Carsten, Dmitrievsky, Sergey, Dohnal, Tadeas, Dolzhikov, Dmitry, Donchenko, Georgy, Dong, Jianmeng, Doroshkevich, Evgeny, Dou, Wei, Dracos, Marcos, Druillole, Frédéric, Du, Ran, Du, Shuxian, Duan, Yujie, Dugas, Katherine, Dusini, Stefano, Duyang, Hongyue, Eck, Jessica, Enqvist, Timo, Fabbri, Andrea, Fahrendholz, Ulrike, Fan, Lei, Fang, Jian, Fang, Wenxing, Fedoseev, Dmitry, Feng, Li-Cheng, Feng, Qichun, Ferraro, Federico, Fournier, Amélie, Fritsch, Fritsch, Gan, Haonan, Gao, Feng, Gao, Feng, Garfagnini, Alberto, Gavrikov, Arsenii, Giammarchi, Marco, Giudice, Nunzio, Gonchar, Maxim, Gong, Guanghua, Gong, Hui, Gornushkin, Yuri, Grassi, Marco, Gromov, Maxim, Gromov, Vasily, Gu, Minghao, Gu, Xiaofei, Gu, Yu, Guan, Mengyun, Guan, Yuduo, Guardone, Nunzio, Guizzetti, Rosa Maria, Guo, Cong, Guo, Wanlei, Hagner, Caren, Han, Hechong, Han, Ran, Han, Yang, He, Jinhong, He, Miao, He, Wei, He, Xinhai, Heinz, Tobias, Hellmuth, Patrick, Heng, Yuekun, Herrera, Rafael, Hor, YuenKeung, Hou, Shaojing, Hsiung, Yee, Hu, Bei-Zhen, Hu, Hang, Hu, Jun, Hu, Peng, Hu, Shouyang, Hu, Tao, Hu, Yuxiang, Hu, Zhuojun, Huang, Guihong, Huang, Hanxiong, Huang, Jinhao, Huang, Junting, Huang, Kaixuan, Huang, Shengheng, Huang, Wenhao, Huang, Xin, Huang, Xingtao, Huang, Yongbo, Hui, Jiaqi, Huo, Lei, Huo, Wenju, Huss, Cédric, Hussain, Safeer, Imbert, Leonard, Ioannisian, Ara, Isocrate, Roberto, Jafar, Arshak, Jelmini, Beatrice, Jeria, Ignacio, Ji, Xiaolu, Jia, Huihui, Jia, Junji, Jian, Siyu, Jiang, Cailian, Jiang, Di, Jiang, Guangzheng, Jiang, Wei, Jiang, Xiaoshan, Jiang, Xiaozhao, Jiang, Yixuan, Jing, Xiaoping, Jollet, Cécile, Kang, Li, Karaparabil, Rebin, Kazarian, Narine, Khan, Ali, Khatun, Amina, Khosonthongkee, Khanchai, Korablev, Denis, Kouzakov, Konstantin, Krasnoperov, Alexey, Kuleshov, Sergey, Kumaran, Sindhujha, Kutovskiy, Nikolay, Labit, Loïc, Lachenmaier, Tobias, Lai, Haojing, Landini, Cecilia, Leblanc, Sébastien, Lefevre, Frederic, Lei, Ruiting, Leitner, Rupert, Leung, Jason, Li, Demin, Li, Fei, Li, Fule, Li, Gaosong, Li, Hongjian, Li, Huang, Li, Jiajun, Li, Min, Li, Nan, Li, Qingjiang, Li, Ruhui, Li, Rui, Li, Shanfeng, Li, Shuo, Li, Tao, Li, Teng, Li, Weidong, Li, Weiguo, Li, Xiaomei, Li, Xiaonan, Li, Xinglong, Li, Yi, Li, Yichen, Li, Yufeng, Li, Zhaohan, Li, Zhibing, Li, Ziyuan, Li, Zonghai, Liang, An-An, Liang, Hao, Liang, Hao, Liao, Jiajun, Liao, Yilin, Liao, Yuzhong, Limphirat, Ayut, Lin, Guey-Lin, Lin, Shengxin, Lin, Tao, Ling, Jiajie, Ling, Xin, Lippi, Ivano, Liu, Caimei, Liu, Fang, Liu, Fengcheng, Liu, Haidong, Liu, Haotian, Liu, Hongbang, Liu, Hongjuan, Liu, Hongtao, Liu, Hongyang, Liu, Jianglai, Liu, Jiaxi, Liu, Jinchang, Liu, Min, Liu, Qian, Liu, Qin, Liu, Runxuan, Liu, Shenghui, Liu, Shubin, Liu, Shulin, Liu, Xiaowei, Liu, Xiwen, Liu, Xuewei, Liu, Yankai, Liu, Zhen, Loi, Lorenzo, Lokhov, Alexey, Lombardi, Paolo, Lombardo, Claudio, Loo, Kai, Lu, Chuan, Lu, Haoqi, Lu, Jingbin, Lu, Junguang, Lu, Meishu, Lu, Peizhi, Lu, Shuxiang, Lu, Xianguo, Lubsandorzhiev, Bayarto, Lubsandorzhiev, Sultim, Ludhova, Livia, Lukanov, Arslan, Luo, Fengjiao, Luo, Guang, Luo, Jianyi, Luo, Shu, Luo, Wuming, Luo, Xiaojie, Lyashuk, Vladimir, Ma, Bangzheng, Ma, Bing, Ma, Qiumei, Ma, Si, Ma, Xiaoyan, Ma, Xubo, Maalmi, Jihane, Mai, Jingyu, Malabarba, Marco, Malyshkin, Yury, Mandujano, Roberto Carlos, Mantovani, Fabio, Mao, Xin, Mao, Yajun, Mari, Stefano M., Marini, Filippo, Martini, Agnese, Mayer, Matthias, Mayilyan, Davit, Mednieks, Ints, Meng, Yue, Meraviglia, Anita, Meregaglia, Anselmo, Meroni, Emanuela, Miramonti, Lino, Mohan, Nikhil, Montuschi, Michele, Reveco, Cristobal Morales, Nastasi, Massimiliano, Naumov, Dmitry V., Naumova, Elena, Navas-Nicolas, Diana, Nemchenok, Igor, Thi, Minh Thuan Nguyen, Nikolaev, Alexey, Ning, Feipeng, Ning, Zhe, Nunokawa, Hiroshi, Oberauer, Lothar, Ochoa-Ricoux, Juan Pedro, Olshevskiy, Alexander, Orestano, Domizia, Ortica, Fausto, Othegraven, Rainer, Paoloni, Alessandro, Parker, George, Parmeggiano, Sergio, Patsias, Achilleas, Pei, Yatian, Pelicci, Luca, Peng, Anguo, Peng, Haiping, Peng, Yu, Peng, Zhaoyuan, Percalli, Elisa, Perrin, Willy, Perrot, Frédéric, Petitjean, Pierre-Alexandre, Petrucci, Fabrizio, Pilarczyk, Oliver, Rico, Luis Felipe Piñeres, Popov, Artyom, Poussot, Pascal, Previtali, Ezio, Qi, Fazhi, Qi, Ming, Qi, Xiaohui, Qian, Sen, Qian, Xiaohui, Qian, Zhen, Qiao, Hao, Qin, Zhonghua, Qiu, Shoukang, Qu, Manhao, Qu, Zhenning, Ranucci, Gioacchino, Re, Alessandra, Rebii, Abdel, Redchuk, Mariia, Reina, Gioele, Ren, Bin, Ren, Jie, Ren, Yuhan, Ricci, Barbara, Rientong, Komkrit, Rifai, Mariam, Roche, Mathieu, Rodphai, Narongkiat, Romani, Aldo, Roskovec, Bedřich, Ruan, Xichao, Rybnikov, Arseniy, Sadovsky, Andrey, Saggese, Paolo, Sandanayake, Deshan, Sangka, Anut, Sava, Giuseppe, Sawangwit, Utane, Schever, Michaela, Schwab, Cédric, Schweizer, Konstantin, Selyunin, Alexandr, Serafini, Andrea, Settimo, Mariangela, Shao, Junyu, Sharov, Vladislav, Shi, Hexi, Shi, Jingyan, Shi, Yanan, Shutov, Vitaly, Sidorenkov, Andrey, Šimkovic, Fedor, Singhal, Apeksha, Sirignano, Chiara, Siripak, Jaruchit, Sisti, Monica, Smirnov, Mikhail, Smirnov, Oleg, Sokolov, Sergey, Songwadhana, Julanan, Soonthornthum, Boonrucksar, Sotnikov, Albert, Sreethawong, Warintorn, Stahl, Achim, Stanco, Luca, Stankevich, Konstantin, Steiger, Hans, Steinmann, Jochen, Sterr, Tobias, Stock, Matthias Raphael, Strati, Virginia, Strizh, Michail, Studenikin, Alexander, Su, Aoqi, Su, Jun, Su, Jun, Sun, Guangbao, Sun, Shifeng, Sun, Xilei, Sun, Yongjie, Sun, Yongzhao, Sun, Zhengyang, Suwonjandee, Narumon, Takenaka, Akira, Tan, Xiaohan, Tang, Jian, Tang, Jingzhe, Tang, Qiang, Tang, Quan, Tang, Xiao, Hariharan, Vidhya Thara, Tkachev, Igor, Tmej, Tomas, Torri, Marco Danilo Claudio, Triossi, Andrea, Trzaska, Wladyslaw, Tung, Yu-Chen, Tuve, Cristina, Ushakov, Nikita, Vedin, Vadim, Venettacci, Carlo, Verde, Giuseppe, Vialkov, Maxim, Viaud, Benoit, Vollbrecht, Cornelius Moritz, Sturm, Katharina von, Vorobel, Vit, Voronin, Dmitriy, Votano, Lucia, Walker, Pablo, Wang, Caishen, Wang, Chung-Hsiang, Wang, En, Wang, Guoli, Wang, Hanwen, Wang, Jian, Wang, Jun, Wang, Li, Wang, Lu, Wang, Meng, Wang, Meng, Wang, Mingyuan, Wang, Qianchuan, Wang, Ruiguang, Wang, Sibo, Wang, Siguang, Wang, Wei, Wang, Wenshuai, Wang, Xi, Wang, Xiangyue, Wang, Yangfu, Wang, Yaoguang, Wang, Yi, Wang, Yi, Wang, Yifang, Wang, Yuanqing, Wang, Yuyi, Wang, Zhe, Wang, Zheng, Wang, Zhimin, Watcharangkool, Apimook, Wei, Wei, Wei, Wei, Wei, Wenlu, Wei, Yadong, Wei, Yuehuan, Wen, Liangjian, Weng, Jun, Wiebusch, Christopher, Wirth, Rosmarie, Wu, Chengxin, Wu, Diru, Wu, Qun, Wu, Yinhui, Wu, Yiyang, Wu, Zhi, Wurm, Michael, Wurtz, Jacques, Wysotzki, Christian, Xi, Yufei, Xia, Dongmei, Xian, Shishen, Xiang, Ziqian, Xiao, Fei, Xiao, Xiang, Xie, Xiaochuan, Xie, Yijun, Xie, Yuguang, Xin, Zhao, Xing, Zhizhong, Xu, Benda, Xu, Cheng, Xu, Donglian, Xu, Fanrong, Xu, Hangkun, Xu, Jiayang, Xu, Jilei, Xu, Jing, Xu, Jinghuan, Xu, Meihang, Xu, Xunjie, Xu, Yin, Xu, Yu, Yan, Baojun, Yan, Qiyu, Yan, Taylor, Yan, Xiongbo, Yan, Yupeng, Yang, Changgen, Yang, Chengfeng, Yang, Fengfan, Yang, Jie, Yang, Lei, Yang, Pengfei, Yang, Xiaoyu, Yang, Yifan, Yang, Yixiang, Yang, Zekun, Yao, Haifeng, Ye, Jiaxuan, Ye, Mei, Ye, Ziping, Yermia, Frédéric, You, Zhengyun, Yu, Boxiang, Yu, Chiye, Yu, Chunxu, Yu, Guojun, Yu, Hongzhao, Yu, Miao, Yu, Xianghui, Yu, Zeyuan, Yu, Zezhong, Yuan, Cenxi, Yuan, Chengzhuo, Yuan, Ying, Yuan, Zhenxiong, Yue, Baobiao, Zafar, Noman, Zamogilnyi, Kirill, Zavadskyi, Vitalii, Zeng, Fanrui, Zeng, Shan, Zeng, Tingxuan, Zeng, Yuda, Zhan, Liang, Zhang, Aiqiang, Zhang, Bin, Zhang, Binting, Zhang, Feiyang, Zhang, Hangchang, Zhang, Haosen, Zhang, Honghao, Zhang, Jialiang, Zhang, Jiawen, Zhang, Jie, Zhang, Jingbo, Zhang, Jinnan, Zhang, Junwei, Zhang, Lei, Zhang, Peng, Zhang, Ping, Zhang, Qingmin, Zhang, Shiqi, Zhang, Shu, Zhang, Shuihan, Zhang, Siyuan, Zhang, Tao, Zhang, Xiaomei, Zhang, Xin, Zhang, Xuantong, Zhang, Yibing, Zhang, Yinhong, Zhang, Yiyu, Zhang, Yongpeng, Zhang, Yu, Zhang, Yuanyuan, Zhang, Yumei, Zhang, Zhenyu, Zhang, Zhijian, Zhao, Jie, Zhao, Rong, Zhao, Runze, Zhao, Shujun, Zhao, Tianhao, Zheng, Hua, Zheng, Yangheng, Zhou, Jing, Zhou, Li, Zhou, Nan, Zhou, Shun, Zhou, Tong, Zhou, Xiang, Zhou, Xing, Zhu, Jingsen, Zhu, Kangfu, Zhu, Kejun, Zhu, Zhihang, Zhuang, Bo, Zhuang, Honglin, Zong, Liang, and Zou, Jiaheng

Published
2025
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60. Multi-calorimetry in light-based neutrino detectors

Author

Cabrera, Anatael, Han, Yang, Calvez, Steven, Chauveau, Emmanuel, Chen, Hanyi, de Kerret, Hervé, Dusini, Stefano, Grassi, Marco, Imbert, Leonard, Li, Jiajun, Mandujano, Roberto Carlos, Navas-Nicolás, Diana, Nunokawa, Hiroshi, Obolensky, Michel, Ochoa-Ricoux, Juan Pedro, Pronost, Guillaume, Viaud, Benoit, and Yermia, Frédéric

Published
2024
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64. North–south pathways, emerging variants, and high climate suitability characterize the recent spread of dengue virus serotypes 2 and 3 in the Dominican Republic

Author

Miguel, Isaac, Feliz, Edwin P., Agramonte, Robinson, Martinez, Pedro V., Vergara, Carlos, Imbert, Yvonne, De la Cruz, Lucia, de Castro, Nurys, Cedano, Odalis, De la Paz, Yamilka, Fonseca, Vagner, Santiago, Gilberto A., Muñoz-Jordán, Jorge L., Peguero, Armando, Paulino-Ramírez, Robert, Grubaugh, Nathan D., de Filippis, Ana Maria Bispo, Alcantara, Luiz Carlos Junior, Rico, Jairo Mendez, Lourenço, José, Franco, Leticia, and Giovanetti, Marta

Published
2024
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68. Precise 113Cd βgA decay spectral shape measurement and interpretation in terms of possible βgA quenching

Author

Bandac, I., Bergé, L., Calvo-Mozota, J. M., Carniti, P., Chapellier, M., Danevich, F. A., Dixon, T., Dumoulin, L., Ferri, F., Giuliani, A., Gotti, C., Gras, Ph., Helis, D. L., Imbert, L., Khalife, H., Kobychev, V. V., Kostensalo, J., Loaiza, P., de Marcillac, P., Marnieros, S., Marrache-Kikuchi, C. A., Martinez, M., Nones, C., Olivieri, E., de Solórzano, A. Ortiz, Pessina, G., Poda, D. V., Scarpaci, J. A., Suhonen, J., Tretyak, V. I., Zarytskyy, M., and Zolotarova, A.

Published
2024
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69. Coercive Hamilton-Jacobi equations in domains: the twin blow-ups method

Author

Forcadel, Nicolas, Imbert, Cyril, and Monneau, Regis

Subjects
Mathematics - Analysis of PDEs
Abstract

In this note, we consider an evolution coercive Hamilton-Jacobi equation posed in a domain and supplemented with a boundary condition. We are interested in proving a comparison principle in the case where the time and the (normal) gradient variables are strongly coupled at the boundary. We elaborate on a method introduced by P.-L. Lions and P. Souganidis (Atti Accad. Naz. Lincei, 2017) to extend their comparison principle to more general boundary conditions and to Hamiltonians that are not globally Lipschitz continuous in the time variable. Their argument relies on a single blow-up procedure after rescaling the semi-solutions to be compared. We refer to our technique as the twin blow-ups method since two blow-ups are performed simultaneously, one for each variable of the doubling variable method. The Lipschitz regularity of the regularized subsolution provides a key Lipschitz inequality satisfied by the two blow-up limits, that are a priori allowed to be infinite. For expository reasons, the result is presented here in the framework of space dimension one and the general case is treated in a companion paper.

Published
2023

70. Non-convex coercive Hamilton-Jacobi equations: Guerand's relaxation revisited

Author

Forcadel, Nicolas, Imbert, Cyril, and Monneau, Regis

Subjects
Mathematics - Analysis of PDEs
Abstract

This work is concerned with Hamilton-Jacobi equations of evolution type posed in domains and supplemented with boundary conditions. Hamiltonians are coercive but are neither convex nor quasiconvex. We analyse boundary conditions when understood in the sense of viscosity solutions. This analysis is based on the study of boundary conditions of evolution type. More precisely, we give a new formula for the relaxed boundary conditions derived by J. Guerand (J. Differ. Equations, 2017). This new point of view unveils a connection between the relaxation operator and the classical Godunov flux from the theory of conservation laws. We apply our methods to two classical boundary value problems. It is shown that the relaxed Neumann boundary condition is expressed in terms of Godunov's flux while the relaxed Dirichlet boundary condition reduces to an obstacle problem at the boundary associated with the lower non-increasing envelope of the Hamiltonian.

Published
2023
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71. Real-time Monitoring for the Next Core-Collapse Supernova in JUNO

Author

Abusleme, Angel, Adam, Thomas, Ahmad, Shakeel, Ahmed, Rizwan, Aiello, Sebastiano, Akram, Muhammad, Aleem, Abid, An, Fengpeng, An, Qi, Andronico, Giuseppe, Anfimov, Nikolay, Antonelli, Vito, Antoshkina, Tatiana, Asavapibhop, Burin, de André, João Pedro Athayde Marcondes, Auguste, Didier, Bai, Weidong, Balashov, Nikita, Baldini, Wander, Barresi, Andrea, Basilico, Davide, Baussan, Eric, Bellato, Marco, Beretta, Marco, Bergnoli, Antonio, Bick, Daniel, Bieger, Lukas, Biktemerova, Svetlana, Birkenfeld, Thilo, Morton-Blake, Iwan, Blum, David, Blyth, Simon, Bolshakova, Anastasia, Bongrand, Mathieu, Bordereau, Clément, Breton, Dominique, Brigatti, Augusto, Brugnera, Riccardo, Bruno, Riccardo, Budano, Antonio, Busto, Jose, Cabrera, Anatael, Caccianiga, Barbara, Cai, Hao, Cai, Xiao, Cai, Yanke, Cai, Zhiyan, Callier, Stéphane, Cammi, Antonio, Campeny, Agustin, Cao, Chuanya, Cao, Guofu, Cao, Jun, Caruso, Rossella, Cerna, Cédric, Cerrone, Vanessa, Chan, Chi, Chang, Jinfan, Chang, Yun, Chatrabhuti, Auttakit, Chen, Chao, Chen, Guoming, Chen, Pingping, Chen, Shaomin, Chen, Yixue, Chen, Yu, Chen, Zhangming, Chen, Zhiyuan, Chen, Zikang, Cheng, Jie, Cheng, Yaping, Cheng, Yu Chin, Chepurnov, Alexander, Chetverikov, Alexey, Chiesa, Davide, Chimenti, Pietro, Chin, Yen-Ting, Chu, Ziliang, Chukanov, Artem, Claverie, Gérard, Clementi, Catia, Clerbaux, Barbara, Molla, Marta Colomer, Di Lorenzo, Selma Conforti, Coppi, Alberto, Corti, Daniele, Csakli, Simon, Corso, Flavio Dal, Dalager, Olivia, Datta, Jaydeep, De La Taille, Christophe, Deng, Zhi, Deng, Ziyan, Ding, Xiaoyu, Ding, Xuefeng, Ding, Yayun, Dirgantara, Bayu, Dittrich, Carsten, Dmitrievsky, Sergey, Dohnal, Tadeas, Dolzhikov, Dmitry, Donchenko, Georgy, Dong, Jianmeng, Doroshkevich, Evgeny, Dou, Wei, Dracos, Marcos, Druillole, Frédéric, Du, Ran, Du, Shuxian, Dugas, Katherine, Dusini, Stefano, Duyang, Hongyue, Eck, Jessica, Enqvist, Timo, Fabbri, Andrea, Fahrendholz, Ulrike, Fan, Lei, Fang, Jian, Fang, Wenxing, Fargetta, Marco, Fedoseev, Dmitry, Fei, Zhengyong, Feng, Li-Cheng, Feng, Qichun, Ferraro, Federico, Fournier, Amélie, Gan, Haonan, Gao, Feng, Garfagnini, Alberto, Gavrikov, Arsenii, Giammarchi, Marco, Giudice, Nunzio, Gonchar, Maxim, Gong, Guanghua, Gong, Hui, Gornushkin, Yuri, Göttel, Alexandre, Grassi, Marco, Gromov, Maxim, Gromov, Vasily, Gu, Minghao, Gu, Xiaofei, Gu, Yu, Guan, Mengyun, Guan, Yuduo, Guardone, Nunzio, Guo, Cong, Guo, Wanlei, Guo, Xinheng, Hagner, Caren, Han, Ran, Han, Yang, He, Miao, He, Wei, Heinz, Tobias, Hellmuth, Patrick, Heng, Yuekun, Herrera, Rafael, Hor, YuenKeung, Hou, Shaojing, Hsiung, Yee, Hu, Bei-Zhen, Hu, Hang, Hu, Jianrun, Hu, Jun, Hu, Shouyang, Hu, Tao, Hu, Yuxiang, Hu, Zhuojun, Huang, Guihong, Huang, Hanxiong, Huang, Jinhao, Huang, Junting, Huang, Kaixuan, Huang, Wenhao, Huang, Xin, Huang, Xingtao, Huang, Yongbo, Hui, Jiaqi, Huo, Lei, Huo, Wenju, Huss, Cédric, Hussain, Safeer, Imbert, Leonard, Ioannisian, Ara, Isocrate, Roberto, Jafar, Arshak, Jelmini, Beatrice, Jeria, Ignacio, Ji, Xiaolu, Jia, Huihui, Jia, Junji, Jian, Siyu, Jiang, Cailian, Jiang, Di, Jiang, Wei, Jiang, Xiaoshan, Jing, Xiaoping, Jollet, Cécile, Kampmann, Philipp, Kang, Li, Karaparambil, Rebin, Kazarian, Narine, Khan, Ali, Khatun, Amina, Khosonthongkee, Khanchai, Korablev, Denis, Kouzakov, Konstantin, Krasnoperov, Alexey, Kuleshov, Sergey, Kutovskiy, Nikolay, Labit, Loïc, Lachenmaier, Tobias, Landini, Cecilia, Leblanc, Sébastien, Lebrin, Victor, Lefevre, Frederic, Lei, Ruiting, Leitner, Rupert, Leung, Jason, Li, Demin, Li, Fei, Li, Fule, Li, Gaosong, Li, Huiling, Li, Jiajun, Li, Mengzhao, Li, Min, Li, Nan, Li, Qingjiang, Li, Ruhui, Li, Rui, Li, Shanfeng, Li, Tao, Li, Teng, Li, Weidong, Li, Weiguo, Li, Xiaomei, Li, Xiaonan, Li, Xinglong, Li, Yi, Li, Yichen, Li, Yufeng, Li, Zhaohan, Li, Zhibing, Li, Ziyuan, Li, Zonghai, Liang, Hao, Liao, Jiajun, Limphirat, Ayut, Lin, Guey-Lin, Lin, Shengxin, Lin, Tao, Ling, Jiajie, Ling, Xin, Lippi, Ivano, Liu, Caimei, Liu, Fang, Liu, Fengcheng, Liu, Haidong, Liu, Haotian, Liu, Hongbang, Liu, Hongjuan, Liu, Hongtao, Liu, Hui, Liu, Jianglai, Liu, Jiaxi, Liu, Jinchang, Liu, Min, Liu, Qian, Liu, Qin, Liu, Runxuan, Liu, Shenghui, Liu, Shubin, Liu, Shulin, Liu, Xiaowei, Liu, Xiwen, Liu, Xuewei, Liu, Yankai, Liu, Zhen, Lokhov, Alexey, Lombardi, Paolo, Lombardo, Claudio, Loo, Kai, Lu, Chuan, Lu, Haoqi, Lu, Jingbin, Lu, Junguang, Lu, Peizhi, Lu, Shuxiang, Lu, Xianguo, Lubsandorzhiev, Bayarto, Lubsandorzhiev, Sultim, Ludhova, Livia, Lukanov, Arslan, Luo, Daibin, Luo, Fengjiao, Luo, Guang, Luo, Jianyi, Luo, Shu, Luo, Wuming, Luo, Xiaojie, Lyashuk, Vladimir, Ma, Bangzheng, Ma, Bing, Ma, Qiumei, Ma, Si, Ma, Xiaoyan, Ma, Xubo, Maalmi, Jihane, Magoni, Marco, Mai, Jingyu, Malyshkin, Yury, Mandujano, Roberto Carlos, Mantovani, Fabio, Mao, Xin, Mao, Yajun, Mari, Stefano M., Marini, Filippo, Martini, Agnese, Mayer, Matthias, Mayilyan, Davit, Mednieks, Ints, Meng, Yue, Meraviglia, Anita, Meregaglia, Anselmo, Meroni, Emanuela, Meyhöfer, David, Miramonti, Lino, Mohan, Nikhil, Montuschi, Michele, Müller, Axel, Nastasi, Massimiliano, Naumov, Dmitry V., Naumova, Elena, Navas-Nicolas, Diana, Nemchenok, Igor, Thi, Minh Thuan Nguyen, Nikolaev, Alexey, Ning, Feipeng, Ning, Zhe, Nunokawa, Hiroshi, Oberauer, Lothar, Ochoa-Ricoux, Juan Pedro, Olshevskiy, Alexander, Orestano, Domizia, Ortica, Fausto, Othegraven, Rainer, Paoloni, Alessandro, Parmeggiano, Sergio, Pei, Yatian, Pelicci, Luca, Peng, Anguo, Peng, Haiping, Peng, Yu, Peng, Zhaoyuan, Perrot, Frédéric, Petitjean, Pierre-Alexandre, Petrucci, Fabrizio, Pilarczyk, Oliver, Rico, Luis Felipe Piñeres, Popov, Artyom, Poussot, Pascal, Previtali, Ezio, Qi, Fazhi, Qi, Ming, Qi, Xiaohui, Qian, Sen, Qian, Xiaohui, Qian, Zhen, Qiao, Hao, Qin, Zhonghua, Qiu, Shoukang, Qu, Manhao, Qu, Zhenning, Ranucci, Gioacchino, Rasheed, Reem, Re, Alessandra, Rebii, Abdel, Redchuk, Mariia, Ren, Bin, Ren, Jie, Ricci, Barbara, Rientong, Komkrit, Rifai, Mariam, Roche, Mathieu, Rodphai, Narongkiat, Romani, Aldo, Roskovec, Bedřich, Ruan, Xichao, Rybnikov, Arseniy, Sadovsky, Andrey, Saggese, Paolo, Sandanayake, Deshan, Sangka, Anut, Sava, Giuseppe, Sawangwit, Utane, Schever, Michaela, Schwab, Cédric, Schweizer, Konstantin, Selyunin, Alexandr, Serafini, Andrea, Settimo, Mariangela, Sharov, Vladislav, Shaydurova, Arina, Shi, Jingyan, Shi, Yanan, Shutov, Vitaly, Sidorenkov, Andrey, Šimkovic, Fedor, Singhal, Apeksha, Sirignano, Chiara, Siripak, Jaruchit, Sisti, Monica, Smirnov, Mikhail, Smirnov, Oleg, Sogo-Bezerra, Thiago, Sokolov, Sergey, Songwadhana, Julanan, Soonthornthum, Boonrucksar, Sotnikov, Albert, Šrámek, Ondřej, Sreethawong, Warintorn, Stahl, Achim, Stanco, Luca, Stankevich, Konstantin, Steiger, Hans, Steinmann, Jochen, Sterr, Tobias, Stock, Matthias Raphael, Strati, Virginia, Studenikin, Alexander, Su, Aoqi, Su, Jun, Sun, Shifeng, Sun, Xilei, Sun, Yongjie, Sun, Yongzhao, Sun, Zhengyang, Suwonjandee, Narumon, Szelezniak, Michal, Takenaka, Akira, Tang, Jian, Tang, Qiang, Tang, Quan, Tang, Xiao, Hariharan, Vidhya Thara, Theisen, Eric, Tietzsch, Alexander, Tkachev, Igor, Tmej, Tomas, Torri, Marco Danilo Claudio, Tortorici, Francesco, Treskov, Konstantin, Triossi, Andrea, Triozzi, Riccardo, Trzaska, Wladyslaw, Tung, Yu-Chen, Tuve, Cristina, Ushakov, Nikita, Vedin, Vadim, Venettacci, Carlo, Verde, Giuseppe, Vialkov, Maxim, Viaud, Benoit, Vollbrecht, Cornelius Moritz, von Sturm, Katharina, Vorobel, Vit, Voronin, Dmitriy, Votano, Lucia, Walker, Pablo, Wang, Caishen, Wang, Chung-Hsiang, Wang, En, Wang, Guoli, Wang, Jian, Wang, Jun, Wang, Li, Wang, Lu, Wang, Meng, Wang, Ruiguang, Wang, Siguang, Wang, Wei, Wang, Wenshuai, Wang, Xi, Wang, Xiangyue, Wang, Yangfu, Wang, Yaoguang, Wang, Yi, Wang, Yifang, Wang, Yuanqing, Wang, Yuyi, Wang, Zhe, Wang, Zheng, Wang, Zhimin, Watcharangkool, Apimook, Wei, Wei, Wei, Wenlu, Wei, Yadong, Wei, Yuehuan, Wen, Kaile, Wen, Liangjian, Weng, Jun, Wiebusch, Christopher, Wirth, Rosmarie, Wonsak, Bjoern, Wu, Diru, Wu, Qun, Wu, Yiyang, Wu, Zhi, Wurm, Michael, Wurtz, Jacques, Wysotzki, Christian, Xi, Yufei, Xia, Dongmei, Xiao, Fei, Xiao, Xiang, Xie, Xiaochuan, Xie, Yuguang, Xie, Zhangquan, Xin, Zhao, Xing, Zhizhong, Xu, Benda, Xu, Cheng, Xu, Donglian, Xu, Fanrong, Xu, Hangkun, Xu, Jilei, Xu, Jing, Xu, Meihang, Xu, Xunjie, Xu, Yin, Xu, Yu, Yan, Baojun, Yan, Qiyu, Yan, Taylor, Yan, Xiongbo, Yan, Yupeng, Yang, Changgen, Yang, Chengfeng, Yang, Jie, Yang, Lei, Yang, Xiaoyu, Yang, Yifan, Yao, Haifeng, Ye, Jiaxuan, Ye, Mei, Ye, Ziping, Yermia, Frédéric, You, Zhengyun, Yu, Boxiang, Yu, Chiye, Yu, Chunxu, Yu, Guojun, Yu, Hongzhao, Yu, Miao, Yu, Xianghui, Yu, Zeyuan, Yu, Zezhong, Yuan, Cenxi, Yuan, Chengzhuo, Yuan, Ying, Yuan, Zhenxiong, Yue, Baobiao, Zafar, Noman, Zavadskyi, Vitalii, Zeng, Fanrui, Zeng, Shan, Zeng, Tingxuan, Zeng, Yuda, Zhan, Liang, Zhang, Aiqiang, Zhang, Bin, Zhang, Binting, Zhang, Feiyang, Zhang, Haosen, Zhang, Honghao, Zhang, Jialiang, Zhang, Jiawen, Zhang, Jie, Zhang, Jingbo, Zhang, Jinnan, ZHANG, Lei, Zhang, Mohan, Zhang, Peng, Zhang, Ping, Zhang, Qingmin, Zhang, Shiqi, Zhang, Shu, Zhang, Shuihan, Zhang, Siyuan, Zhang, Tao, Zhang, Xiaomei, Zhang, Xin, Zhang, Xuantong, Zhang, Yinhong, Zhang, Yiyu, Zhang, Yongpeng, Zhang, Yu, Zhang, Yuanyuan, Zhang, Yumei, Zhang, Zhenyu, Zhang, Zhijian, Zhao, Jie, Zhao, Rong, Zhao, Runze, Zhao, Shujun, Zheng, Dongqin, Zheng, Hua, Zheng, Yangheng, Zhong, Weirong, Zhou, Jing, Zhou, Li, Zhou, Nan, Zhou, Shun, Zhou, Tong, Zhou, Xiang, Zhu, Jingsen, Zhu, Kangfu, Zhu, Kejun, Zhu, Zhihang, Zhuang, Bo, Zhuang, Honglin, Zong, Liang, Zou, Jiaheng, and Züfle, Jan

Subjects
High Energy Physics - Experiment, Astrophysics - High Energy Astrophysical Phenomena, High Energy Physics - Phenomenology
Abstract

The core-collapse supernova (CCSN) is considered one of the most energetic astrophysical events in the universe. The early and prompt detection of neutrinos before (pre-SN) and during the supernova (SN) burst presents a unique opportunity for multi-messenger observations of CCSN events. In this study, we describe the monitoring concept and present the sensitivity of the system to pre-SN and SN neutrinos at the Jiangmen Underground Neutrino Observatory (JUNO), a 20 kton liquid scintillator detector currently under construction in South China. The real-time monitoring system is designed to ensure both prompt alert speed and comprehensive coverage of progenitor stars. It incorporates prompt monitors on the electronic board as well as online monitors at the data acquisition stage. Assuming a false alert rate of 1 per year, this monitoring system exhibits sensitivity to pre-SN neutrinos up to a distance of approximately 1.6 (0.9) kiloparsecs and SN neutrinos up to about 370 (360) kiloparsecs for a progenitor mass of 30 solar masses, considering both normal and inverted mass ordering scenarios. The pointing ability of the CCSN is evaluated by analyzing the accumulated event anisotropy of inverse beta decay interactions from pre-SN or SN neutrinos. This, along with the early alert, can play a crucial role in facilitating follow-up multi-messenger observations of the next galactic or nearby extragalactic CCSN., Comment: 24 pages, 9 figures, accepted for the publication at JCAP

Published
2023

72. Searching for beyond the Standard Model physics using the improved description of 100Mo 2νββ decay spectral shape with CUPID-Mo

Author

Augier, C, Barabash, AS, Bellini, F, Benato, G, Beretta, M, Bergé, L, Billard, J, Borovlev, Yu A, Cardani, L, Casali, N, Cazes, A, Celi, E, Chapellier, M, Chiesa, D, Dafinei, I, Danevich, FA, De Jesus, M, Dixon, T, Dumoulin, L, Eitel, K, Ferri, F, Fujikawa, BK, Gascon, J, Gironi, L, Giuliani, A, Grigorieva, VD, Gros, M, Helis, DL, Huang, HZ, Huang, R, Imbert, L, Juillard, A, Khalife, H, Kleifges, M, Kobychev, VV, Kolomensky, Yu G, Konovalov, SI, Kotila, J, Loaiza, P, Ma, L, Makarov, EP, de Marcillac, P, Mariam, R, Marini, L, Marnieros, S, Navick, XF, Nones, C, Norman, EB, Olivieri, E, Ouellet, JL, Pagnanini, L, Pattavina, L, Paul, B, Pavan, M, Peng, H, Pessina, G, Pirro, S, Poda, DV, Polischuk, OG, Pozzi, S, Previtali, E, Redon, Th, Rojas, A, Rozov, S, Sanglard, V, Scarpaci, JA, Schmidt, B, Shen, Y, Shlegel, VN, Šimkovic, F, Singh, V, Tomei, C, Tretyak, VI, Umatov, VI, Vagneron, L, Velázquez, M, Ware, B, Welliver, B, Winslow, L, Xue, M, Yakushev, E, Zarytskyy, M, and Zolotarova, AS

Subjects
Nuclear and Plasma Physics, Particle and High Energy Physics, Physical Sciences, Atomic, Molecular, Nuclear, Particle and Plasma Physics, Quantum Physics, Nuclear & Particles Physics, Astronomical sciences, Atomic, molecular and optical physics, Particle and high energy physics
Abstract

The current experiments searching for neutrinoless double-β (0νββ) decay also collect large statistics of Standard Model allowed two-neutrino double-β (2νββ) decay events. These can be used to search for Beyond Standard Model (BSM) physics via 2νββ decay spectral distortions. 100Mo has a natural advantage due to its relatively short half-life, allowing higher 2νββ decay statistics at equal exposures compared to the other isotopes. We demonstrate the potential of the dual read-out bolometric technique exploiting a 100Mo exposure of 1.47 kg × years, acquired in the CUPID-Mo experiment at the Modane underground laboratory (France). We set limits on 0νββ decays with the emission of one or more Majorons, on 2νββ decay with Lorentz violation, and 2νββ decay with a sterile neutrino emission. In this analysis, we investigate the systematic uncertainty induced by modeling the 2νββ decay spectral shape parameterized through an improved model, an effect never considered before. This work motivates searches for BSM processes in the upcoming CUPID experiment, which will collect the largest amount of 2νββ decay events among the next-generation experiments.

Published
2024

75. Test of $^{116}$CdWO$_4$ and Li$_2$MoO$_4$ scintillating bolometers in the CROSS underground facility with upgraded detector suspension

Author

Ahmine, A., Bandac, I. C., Barabash, A. S., Berest, V., Bergé, L., Calvo-Mozota, J. M., Carniti, P., Chapellier, M., Dafinei, I., Danevich, F. A., Dixon, T., Dumoulin, L., Ferri, F., Giuliani, A., Gotti, C., Gras, P., Helis, D. L., Ianni, A., Imbert, L., Khalife, H., Kobychev, V. V., Konovalov, S. I., Loaiza, P., de Marcillac, P., Marnieros, S., Marrache-Kikuchi, C. A., Martinez, M., Nones, C., Olivieri, E., de Solórzano, A. Ortiz, Peinaud, Y., Pessina, G., Poda, D. V., Redon, Th., Rosier, Ph., Scarpaci, J. A., Tretyak, V. I., Umatov, V. I., Velazquez, M., Zarytskyy, M. M., and Zolotarova, A.

Subjects
Physics - Instrumentation and Detectors, Nuclear Experiment
Abstract

In preparation to the CROSS $2\beta$ decay experiment, we installed a new detector suspension with magnetic dumping inside a pulse-tube cryostat of a dedicated low-background facility at the LSC (Spain). The suspension was tested with two scintillating bolometers based on large-volume 116CdWO4 (CWO-enr) and Li2MoO4 (LMO) crystals. The former, a reference device, was used for testing new noise conditions and for comparing bolometric performance of an advanced Li2MoO4 crystal developed in the framework of the CLYMENE project, in view of next-generation double-beta decay experiments like CUPID. We cooled down detectors to 15 mK and achieved high performance for all tested devices. In particular both CWO-enr and LMO bolometers demonstrated the energy resolution of 6 keV FWHM for the 2.6 MeV gamma quanta, among the best for thermal detectors based on such compounds. The baseline noise resolution (FWHM) of the CWO-enr detector was improved by 2 keV, compared to the best previous measurement of this detector in the CROSS facility, while the noise of the Ge-based optical bolometer was improved by a factor 2, to 100 eV FWHM. Despite of the evident progress in the improving of noise conditions of the set-up, we see high-frequency harmonics of a pulse-tube induced noise, suggesting a noise pick-up by cabling. Another Ge light detector was assisted with the signal amplification exploiting the Neganov-Trofimov-Luke effect, which allowed to reach 20 eV FWHM noise resolution by applying 60 V electrode bias. Highly-efficient particle identification was achieved with both detectors, despite a low scintillation efficiency of the LMO material. The radiopurity level of the LMO crystal is rather high; only traces of 210Po and 226Ra were detected (0.1 mBq/kg each), while the 228Th activity is expected to be at least an order of magnitude lower, as well as a 40K activity is found to be < 6 mBq/kg., Comment: Prepared for submission to JINST, 26 pages, 8 figures, 2 tables

Published
2023

76. Measurement of the $2\nu\beta\beta$ decay rate and spectral shape of $^{100}$Mo from the CUPID-Mo experiment

Author

Augier, C., Barabash, A. S., Bellini, F., Benato, G., Beretta, 6 M., Berge, L., Billard, J., Borovlev, Yu. A., Cardani, L., Casali, N., Cazes, A., Celi, E., Chapellier, M., Chiesa, D., Dafinei, I., Danevich, F. A., De Jesus, M., Dixon, T., Dumoulin, L., Eitel, K., Ferri, F., Fujikawa, B. K., Gascon, J., Gironi, L., Giuliani, A., Grigorieva, V. D., Gros, M., Helis, D. L., Huang, H. Z., Huang, R., Imbert, L., Johnston, J., Juillard, A., Khalife, H., Kleifges, M., Kobychev, V. V., Kolomensky, Yu. G., Konovalov, S. I., Kotila, J., Loaiza, P., Ma, L., Makarov, E. P., de Marcillac, P., Mariam, R., Marini, L., Marnieros, S., Navick, X. -F., Nones, C., Norman, E. B., Olivieri, E., Ouellet, J. L., Pagnanini, L., Pattavina, L., Paul, B., Pavan, M., Peng, H., Pessina, G., Pirro, S., Poda, D. V., Polischuk, O. G., Pozzi, S., Previtali, E., Redon, Th., Rojas, A., Rozov, S., Sanglard, V., Scarpaci, J. A., Schmidt, B., Shen, Y., Shlegel, V. N., Simkovic, F., Singh, V., Tomei, C., Tretyak, V. I., Umatov, V. I., Vagneron, L., Velazquez, M., Ware, B., Welliver, B., Winslow, L., Xue, M., Yakushev, E., Zarytskyy, M., and Zolotarova, A. S.

Subjects
Nuclear Experiment, High Energy Physics - Experiment
Abstract

Neutrinoless double beta decay ($0\nu\beta\beta$) is a yet unobserved nuclear process which would demonstrate Lepton Number violation, a clear evidence of beyond Standard Model physics. The process two neutrino double beta decay ($2\nu\beta\beta)$ is allowed by the Standard Model and has been measured in numerous experiments. In this letter, we report a measurement of $2\nu\beta\beta$ decay half-life of $^{100}$Mo to the ground state of $^{100}$Ru of $(7.07~\pm~0.02~\text{(stat.)}~\pm~0.11~\text{(syst.)})~\times~10^{18}$~yr by the CUPID-Mo experiment. With a relative precision of $\pm~1.6$ \% this is the most precise measurement to date of a $2\nu\beta\beta$ decay rate in $^{100}$Mo. In addition, we constrain higher-order corrections to the spectral shape which provides complementary nuclear structure information. We report a novel measurement of the shape factor $\xi_{3,1}=0.45~\pm 0.03~\text{(stat.)} \ \pm 0.05 \ \text{(syst.)}$, which is compared to theoretical predictions for different nuclear models. We also extract the first value for the effective axial vector coupling constant obtained from a spectral shape study of $2\nu\beta\beta$ decay., Comment: 8 pages, 5 figures

Published
2023

77. The background model of the CUPID-Mo $0\nu\beta\beta$ experiment

Author

Collaboration, CUPID-Mo, Augier, C., Barabash, A. S., Bellini, F., Benato, G., Beretta, M., Bergé, L., Billard, J., Borovlev, Yu. A., Cardani, L., Casali, N., Cazes, A., Celi, E., Chapellier, M., Chiesa, D., Dafinei, I., Danevich, F. A., De Jesus, M., de Marcillac, P., Dixon, T., Dumoulin, L., Eitel, K., Ferri, F., Fujikawa, B. K., Gascon, J., Gironi, L., Giuliani, A., Grigorieva, V. D., Gros, M., Helis, D. L., Huang, H. Z., Huang, R., Imbert, L., Johnston, J., Juillard, A., Khalife, H., Kleifges, M., Kobychev, V. V., Kolomensky, Yu. G., Konovalov, S. I., Kotila, J., Loaiza, P., Ma, L., Makarov, E. P., Mariam, R., Marini, L., Marnieros, S., Navick, X. F., Nones, C., Norman, E. B., Olivieri, E., Ouellet, J. L., Pagnanini, L., Pattavina, L., Pavan, M., Peng, H., Pessina, G., Pirro, S., Poda, D. V., Polischuk, O. G., Pozzi, S., Previtali, E., Redon, Th., Rojas, A., Rozov, S., Sanglard, V., Scarpaci, J. A., Schmidt, B., Shen, Y., Shlegel, V. N., Singh, V., Tomei, C., Tretyak, V. I., Umatov, V. I., Vagneron, L., Velázquez, M., Welliver, B., Winslow, L., Xue, M., Yakushev, E., Zarytskyy, M., and Zolotarova, A. S.

Subjects
High Energy Physics - Experiment, Physics - Instrumentation and Detectors
Abstract

CUPID-Mo, located in the Laboratoire Souterrain de Modane (France), was a demonstrator for the next generation $0\nu\beta\beta$ decay experiment, CUPID. It consisted of an array of 20 enriched Li$_{2}$$ ^{100}$MoO$_4$ bolometers and 20 Ge light detectors and has demonstrated that the technology of scintillating bolometers with particle identification capabilities is mature. Furthermore, CUPID-Mo can inform and validate the background prediction for CUPID. In this paper, we present a detailed model of the CUPID-Mo backgrounds. This model is able to describe well the features of the experimental data and enables studies of the $2\nu\beta\beta$ decay and other processes with high precision. We also measure the radio-purity of the Li$_{2}$$^{100}$MoO$_4$ crystals which are found to be sufficient for the CUPID goals. Finally, we also obtain a background index in the region of interest of 3.7$^{+0.9}_{-0.8}$(stat)$^{+1.5}_{-0.7}$(syst)$\times10^{-3}$counts/$\Delta$E$_{FWHM}$/mol$_{iso}$/yr, the lowest in a bolometric $0\nu\beta\beta$ decay experiment.

Published
2023
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78. ChatGPT for Learning HCI Techniques: A Case Study on Interviews for Personas

Author

Jose Barambones, Cristian Moral, Angelica de Antonio, Ricardo Imbert, Loic Martinez-Normand, and Elena Villalba-Mora

Abstract

Before interacting with real users, developers must be proficient in human--computer interaction (HCI) so as not to exhaust user patience and availability. For that, substantial training and practice are required, but it is costly to create a variety of high-quality HCI training materials. In this context, chat generative pretrained transformer (ChatGPT) and other chatbots based on large language models (LLMs) offer an opportunity to generate training materials of acceptable quality without foregoing specific human characteristics present in real-world scenarios. Personas is a user-centered design method that encompasses fictitious but believable user archetypes to help designers understand and empathize with their target audience during product design. We conducted an exploratory study on the Personas technique, addressing the validity and believability of interviews designed by HCI trainers and answered by ChatGPT-simulated users, which can be used as training material for persona creation. Specifically, we employed ChatGPT to respond to interviews designed by user experience (UX) experts. Two groups, HCI professors and professionals, then evaluated the validity of the generated materials considering quality, usefulness, UX, and ethics. The results show that both groups rated the interviews as believable and helpful for Personas training. However, some concerns about response repetition and low response variability suggested the need for further research on improved prompt design in order to generate more diverse and well-developed responses. The findings of this study provide insight into how HCI trainers can use ChatGPT to help their students master persona creation skills before working with real users in real-world scenarios for the first time.

Published
2024
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81. Measurement of the 2νββ Decay Rate and Spectral Shape of Mo100 from the CUPID-Mo Experiment

Author

Augier, C, Barabash, AS, Bellini, F, Benato, G, Beretta, M, Bergé, L, Billard, J, Borovlev, Yu A, Cardani, L, Casali, N, Cazes, A, Celi, E, Chapellier, M, Chiesa, D, Dafinei, I, Danevich, FA, De Jesus, M, Dixon, T, Dumoulin, L, Eitel, K, Ferri, F, Fujikawa, BK, Gascon, J, Gironi, L, Giuliani, A, Grigorieva, VD, Gros, M, Helis, DL, Huang, HZ, Huang, R, Imbert, L, Johnston, J, Juillard, A, Khalife, H, Kleifges, M, Kobychev, VV, Kolomensky, Yu G, Konovalov, SI, Kotila, J, Loaiza, P, Ma, L, Makarov, EP, de Marcillac, P, Mariam, R, Marini, L, Marnieros, S, Navick, X-F, Nones, C, Norman, EB, Olivieri, E, Ouellet, JL, Pagnanini, L, Pattavina, L, Paul, B, Pavan, M, Peng, H, Pessina, G, Pirro, S, Poda, DV, Polischuk, OG, Pozzi, S, Previtali, E, Redon, Th, Rojas, A, Rozov, S, Sanglard, V, Scarpaci, JA, Schmidt, B, Shen, Y, Shlegel, VN, Šimkovic, F, Singh, V, Tomei, C, Tretyak, VI, Umatov, VI, Vagneron, L, Velázquez, M, Ware, B, Welliver, B, Winslow, L, Xue, M, Yakushev, E, Zarytskyy, M, and Zolotarova, AS

Subjects
Nuclear and Plasma Physics, Particle and High Energy Physics, Physical Sciences, CUPID-Mo Collaboration, Mathematical Sciences, Engineering, General Physics, Mathematical sciences, Physical sciences
Abstract

Neutrinoless double beta decay (0νββ) is a yet unobserved nuclear process that would demonstrate Lepton number violation, a clear evidence of beyond standard model physics. The process two neutrino double beta decay (2νββ) is allowed by the standard model and has been measured in numerous experiments. In this Letter, we report a measurement of 2νββ decay half-life of ^{100}Mo to the ground state of ^{100}Ru of [7.07±0.02(stat)±0.11(syst)]×10^{18}  yr by the CUPID-Mo experiment. With a relative precision of ±1.6% this is the most precise measurement to date of a 2νββ decay rate in ^{100}Mo. In addition, we constrain higher-order corrections to the spectral shape, which provides complementary nuclear structure information. We report a novel measurement of the shape factor ξ_{3,1}=0.45±0.03(stat)±0.05(syst) based on a constraint on the ratio of higher-order terms from theory, which can be reliably calculated. This is compared to theoretical predictions for different nuclear models. We also extract the first value for the effective axial vector coupling constant obtained from a spectral shape study of 2νββ decay.

Published
2023

82. A first test of CUPID prototypal light detectors with NTD-Ge sensors in a pulse-tube cryostat

Author

CUPID collaboration, Alfonso, K., Armatol, A., Augier, C., Avignone III, F. T., Azzolini, O., Balata, M., Barabash, A. S., Bari, G., Barresi, A., Baudin, D., Bellini, F., Benato, G., Berest, V., Beretta, M., Bettelli, M., Biassoni, M., Billard, J., Boldrini, V., Branca, A., Brofferio, C., Bucci, C., Camilleri, J., Campani, A., Capelli, C., Capelli, S., Cappelli, L., Cardani, L., Carniti, P., Casali, N., Celi, E., Chang, C., Chiesa, D., Clemenza, M., Colantoni, I., Copello, S., Craft, E., Cremonesi, O., Creswick, R. J., Cruciani, A., D'Addabbo, A., D'Imperio, G., Dabagov, S., Dafinei, I., Danevich, F. A., De Jesus, M., de Marcillac, P., Dell'Oro, S., Di Domizio, S., Di Lorenzo, S., Dixon, T., Dompé, V., Drobizhev, A., Dumoulin, L., Fantini, G., Faverzani, M., Ferri, E., Ferri, F., Ferroni, F., Figueroa-Feliciano, E., Foggetta, L., Formaggio, J., Franceschi, A., Fu, C., Fu, S., Fujikawa, B. K., Gallas, A., Gascon, J., Ghislandi, S., Giachero, A., Gianvecchio, A., Girola, M., Gironi, L., Giuliani, A., Gorla, P., Gotti, C., Grant, C., Gras, P., Guillaumon, P. V., Gutierrez, T. D., Han, K., Hansen, E. V., Heeger, K. M., Helis, D. L., Huang, H. Z., Imbert, L., Johnston, J., Juillard, A., Karapetrov, G., Keppel, G., Khalife, H., Kobychev, V. V., Kolomensky, Yu. G., Konovalov, S. I., Kowalski, R., Langford, T., Lefevre, M., Liu, R., Liu, Y., Loaiza, P., Ma, L., Madhukuttan, M., Mancarella, F., Marini, L., Marnieros, S., Martinez, M., Maruyama, R. H., Mas, Ph., Mayer, D., Mazzitelli, G., Mei, Y., Milana, S., Morganti, S., Napolitano, T., Nastasi, M., Nikkel, J., Nisi, S., Nones, C., Norman, E. B., Novosad, V., Nutini, I., O'Donnell, T., Olivieri, E., Olmi, M., Ouellet, J. L., Pagan, S., Pagliarone, C., Pagnanini, L., Pattavina, L., Pavan, M., Peng, H., Pessina, G., Pettinacci, V., Pira, C., Pirro, S., Poda, D. V., Polischuk, O. G., Ponce, I., Pozzi, S., Previtali, E., Puiu, A., Quitadamo, S., Ressa, A., Rizzoli, R., Rosenfeld, C., Rosier, P., Scarpaci, J. A., Schmidt, B., Sharma, V., Shlegel, V. N., Singh, V., Sisti, M., Slocum, P., Speller, D., Surukuchi, P. T., Taffarello, L., Tomei, C., Torres, J. A., Tretyak, V. I., Tsymbaliuk, A., Velazquez, M., Vetter, K. J., Wagaarachchi, S. L., Wang, G., Wang, L., Wang, R., Welliver, B., Wilson, J., Wilson, K., Winslow, L. A., Xue, M., Yan, L., Yang, J., Yefremenko, V., Umatov, V. I., Zarytskyy, M. M., Zhang, J., Zolotarova, A., and Zucchelli, S.

Subjects
Physics - Instrumentation and Detectors, Nuclear Experiment
Abstract

CUPID is a next-generation bolometric experiment aiming at searching for neutrinoless double-beta decay with ~250 kg of isotopic mass of $^{100}$Mo. It will operate at $\sim$10 mK in a cryostat currently hosting a similar-scale bolometric array for the CUORE experiment at the Gran Sasso National Laboratory (Italy). CUPID will be based on large-volume scintillating bolometers consisting of $^{100}$Mo-enriched Li$_2$MoO$_4$ crystals, facing thin Ge-wafer-based bolometric light detectors. In the CUPID design, the detector structure is novel and needs to be validated. In particular, the CUORE cryostat presents a high level of mechanical vibrations due to the use of pulse tubes and the effect of vibrations on the detector performance must be investigated. In this paper we report the first test of the CUPID-design bolometric light detectors with NTD-Ge sensors in a dilution refrigerator equipped with a pulse tube in an above-ground lab. Light detectors are characterized in terms of sensitivity, energy resolution, pulse time constants, and noise power spectrum. Despite the challenging noisy environment due to pulse-tube-induced vibrations, we demonstrate that all the four tested light detectors comply with the CUPID goal in terms of intrinsic energy resolution of 100 eV RMS baseline noise. Indeed, we have measured 70--90 eV RMS for the four devices, which show an excellent reproducibility. We have also obtained outstanding energy resolutions at the 356 keV line from a $^{133}$Ba source with one light detector achieving 0.71(5) keV FWHM, which is -- to our knowledge -- the best ever obtained when compared to $\gamma$ detectors of any technology in this energy range., Comment: Prepared for submission to JINST; 16 pages, 7 figures, and 1 table

Published
2023
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83. Twelve-crystal prototype of Li$_2$MoO$_4$ scintillating bolometers for CUPID and CROSS experiments

Author

CUPID, collaborations, CROSS, Alfonso, K., Armatol, A., Augier, C., Avignone III, F. T., Azzolini, O., Balata, M., Bandac, I. C., Barabash, A. S., Bari, G., Barresi, A., Baudin, D., Bellini, F., Benato, G., Berest, V., Beretta, M., Bettelli, M., Biassoni, M., Billard, J., Boldrini, V., Branca, A., Brofferio, C., Bucci, C., Calvo-Mozota, J. M., Camilleri, J., Campani, A., Capelli, C., Capelli, S., Cappelli, L., Cardani, L., Carniti, P., Casali, N., Celi, E., Chang, C., Chiesa, D., Clemenza, M., Colantoni, I., Copello, S., Craft, E., Cremonesi, O., Creswick, R. J., Cruciani, A., D'Addabbo, A., D'Imperio, G., Dabagov, S., Dafinei, I., Danevich, F. A., De Jesus, M., de Marcillac, P., Dell'Oro, S., Di Domizio, S., Di Lorenzo, S., Dixon, T., Dompé, V., Drobizhev, A., Dumoulin, L., Fantini, G., Faverzani, M., Ferri, E., Ferri, F., Ferroni, F., Figueroa-Feliciano, E., Foggetta, L., Formaggio, J., Franceschi, A., Fu, C., Fu, S., Fujikawa, B. K., Gallas, A., Gascon, J., Ghislandi, S., Giachero, A., Gianvecchio, A., Girola, M., Gironi, L., Giuliani, A., Gorla, P., Gotti, C., Grant, C., Gras, P., Guillaumon, P. V., Gutierrez, T. D., Han, K., Hansen, E. V., Heeger, K. M., Helis, D. L., Huang, H. Z., Ianni, A., Imbert, L., Johnston, J., Juillard, A., Karapetrov, G., Keppel, G., Khalife, H., Kobychev, V. V., Kolomensky, Yu. G., Konovalov, S. I., Kowalski, R., Langford, T., Lefevre, M., Liu, R., Liu, Y., Loaiza, P., Ma, L., Madhukuttan, M., Mancarella, F., Marrache-Kikuchi, C. A., Marini, L., Marnieros, S., Martinez, M., Maruyama, R. H., Mas, Ph., Mayer, D., Mazzitelli, G., Mei, Y., Milana, S., Morganti, S., Napolitano, T., Nastasi, M., Nikkel, J., Nisi, S., Nones, C., Norman, E. B., Novosad, V., Nutini, I., O'Donnell, T., Olivieri, E., Olmi, M., Ouellet, J. L., Pagan, S., Pagliarone, C., Pagnanini, L., Pattavina, L., Pavan, M., Peng, H., Pessina, G., Pettinacci, V., Pira, C., Pirro, S., Poda, D. V., Polischuk, O. G., Ponce, I., Pozzi, S., Previtali, E., Puiu, A., Quitadamo, S., Ressa, A., Rizzoli, R., Rosenfeld, C., Rosier, P., Scarpaci, J. A., Schmidt, B., Sharma, V., Shlegel, V. N., Singh, V., Sisti, M., Slocum, P., Speller, D., Surukuchi, P. T., Taffarello, L., Tomei, C., Torres, J. A., Tretyak, V. I., Tsymbaliuk, A., Velazquez, M., Vetter, K. J., Wagaarachchi, S. L., Wang, G., Wang, L., Wang, R., Welliver, B., Wilson, J., Wilson, K., Winslow, L. A., Xue, M., Yan, L., Yang, J., Yefremenko, V., Umatov, V. I., Zarytskyy, M. M., Zhang, J., Zolotarova, A., and Zucchelli, S.

Subjects
Physics - Instrumentation and Detectors, Nuclear Experiment
Abstract

An array of twelve 0.28 kg lithium molybdate (LMO) low-temperature bolometers equipped with 16 bolometric Ge light detectors, aiming at optimization of detector structure for CROSS and CUPID double-beta decay experiments, was constructed and tested in a low-background pulse-tube-based cryostat at the Canfranc underground laboratory in Spain. Performance of the scintillating bolometers was studied depending on the size of phonon NTD-Ge sensors glued to both LMO and Ge absorbers, shape of the Ge light detectors (circular vs. square, from two suppliers), in different light collection conditions (with and without reflector, with aluminum coated LMO crystal surface). The scintillating bolometer array was operated over 8 months in the low-background conditions that allowed to probe a very low, $\mu$Bq/kg, level of the LMO crystals radioactive contamination by $^{228}$Th and $^{226}$Ra., Comment: Prepared for submission to JINST; 23 pages, 9 figures, and 4 tables

Published
2023
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84. JUNO sensitivity to $^7$Be, $pep$, and CNO solar neutrinos

Author

Abusleme, Angel, Adam, Thomas, Ahmad, Shakeel, Ahmed, Rizwan, Aiello, Sebastiano, Akram, Muhammad, Aleem, Abid, Alexandros, Tsagkarakis, An, Fengpeng, An, Qi, Andronico, Giuseppe, Anfimov, Nikolay, Antonelli, Vito, Antoshkina, Tatiana, Asavapibhop, Burin, de André, João Pedro Athayde Marcondes, Auguste, Didier, Bai, Weidong, Balashov, Nikita, Baldini, Wander, Barresi, Andrea, Basilico, Davide, Baussan, Eric, Bellato, Marco, Beretta, Marco, Bergnoli, Antonio, Bick, Daniel, Bieger, Lukas, Biktemerova, Svetlana, Birkenfeld, Thilo, Blum, David, Blyth, Simon, Bolshakova, Anastasia, Bongrand, Mathieu, Bordereau, Clément, Breton, Dominique, Brigatti, Augusto, Brugnera, Riccardo, Bruno, Riccardo, Budano, Antonio, Busto, Jose, Cabrera, Anatael, Caccianiga, Barbara, Cai, Hao, Cai, Xiao, Cai, Yanke, Cai, Zhiyan, Callier, Stéphane, Cammi, Antonio, Campeny, Agustin, Cao, Chuanya, Cao, Guofu, Cao, Jun, Caruso, Rossella, Cerna, Cédric, Cerrone, Vanessa, Chan, Chi, Chang, Jinfan, Chang, Yun, Chen, Chao, Chen, Guoming, Chen, Pingping, Chen, Shaomin, Chen, Yixue, Chen, Yu, Chen, Zhiyuan, Chen, Zikang, Cheng, Jie, Cheng, Yaping, Cheng, Yu Chin, Chepurnov, Alexander, Chetverikov, Alexey, Chiesa, Davide, Chimenti, Pietro, Chu, Ziliang, Chukanov, Artem, Claverie, Gérard, Clementi, Catia, Clerbaux, Barbara, Molla, Marta Colomer, Di Lorenzo, Selma Conforti, Coppi, Alberto, Corti, Daniele, Csakli, Simon, Corso, Flavio Dal, Dalager, Olivia, Datta, Jaydeep, De La Taille, Christophe, Deng, Zhi, Deng, Ziyan, Depnering, Wilfried, Ding, Xiaoyu, Ding, Xuefeng, Ding, Yayun, Dirgantara, Bayu, Dittrich, Carsten, Dmitrievsky, Sergey, Dohnal, Tadeas, Dolzhikov, Dmitry, Donchenko, Georgy, Dong, Jianmeng, Doroshkevich, Evgeny, Dou, Wei, Dracos, Marcos, Druillole, Frédéric, Du, Ran, Du, Shuxian, Dugas, Katherine, Dusini, Stefano, Duyang, Hongyue, Eck, Jessica, Enqvist, Timo, Fabbri, Andrea, Fahrendholz, Ulrike, Fan, Lei, Fang, Jian, Fang, Wenxing, Fargetta, Marco, Fedoseev, Dmitry, Fei, Zhengyong, Feng, Li-Cheng, Feng, Qichun, Ferraro, Federico, Fournier, Amélie, Gan, Haonan, Gao, Feng, Garfagnini, Alberto, Gavrikov, Arsenii, Giammarchi, Marco, Giudice, Nunzio, Gonchar, Maxim, Gong, Guanghua, Gong, Hui, Gornushkin, Yuri, Göttel, Alexandre, Grassi, Marco, Gromov, Maxim, Gromov, Vasily, Gu, Minghao, Gu, Xiaofei, Gu, Yu, Guan, Mengyun, Guan, Yuduo, Guardone, Nunzio, Guo, Cong, Guo, Wanlei, Guo, Xinheng, Hagner, Caren, Han, Ran, Han, Yang, He, Miao, He, Wei, Heinz, Tobias, Hellmuth, Patrick, Heng, Yuekun, Herrera, Rafael, Hor, YuenKeung, Hou, Shaojing, Hsiung, Yee, Hu, Bei-Zhen, Hu, Hang, Hu, Jianrun, Hu, Jun, Hu, Shouyang, Hu, Tao, Hu, Yuxiang, Hu, Zhuojun, Huang, Guihong, Huang, Hanxiong, Huang, Jinhao, Huang, Junting, Huang, Kaixuan, Huang, Wenhao, Huang, Xin, Huang, Xingtao, Huang, Yongbo, Hui, Jiaqi, Huo, Lei, Huo, Wenju, Huss, Cédric, Hussain, Safeer, Imbert, Leonard, Ioannisian, Ara, Isocrate, Roberto, Jelmini, Beatrice, Jeria, Ignacio, Ji, Xiaolu, Jia, Huihui, Jia, Junji, Jian, Siyu, Jiang, Cailian, Jiang, Di, Jiang, Wei, Jiang, Xiaoshan, Jing, Xiaoping, Jollet, Cécile, Kampmann, Philipp, Kang, Li, Karaparambil, Rebin, Kazarian, Narine, Khan, Ali, Khatun, Amina, Khosonthongkee, Khanchai, Korablev, Denis, Kouzakov, Konstantin, Krasnoperov, Alexey, Kuleshov, Sergey, Kutovskiy, Nikolay, Lachenmaier, Tobias, Landini, Cecilia, Leblanc, Sébastien, Lebrin, Victor, Lefevre, Frederic, Lei, Ruiting, Leitner, Rupert, Leung, Jason, Li, Demin, Li, Fei, Li, Fule, Li, Gaosong, Li, Huiling, Li, Jiajun, Li, Mengzhao, Li, Min, Li, Nan, Li, Qingjiang, Li, Ruhui, Li, Rui, Li, Shanfeng, Li, Tao, Li, Teng, Li, Weidong, Li, Weiguo, Li, Xiaomei, Li, Xiaonan, Li, Xinglong, Li, Yi, Li, Yichen, Li, Yufeng, Li, Zepeng, Li, Zhaohan, Li, Zhibing, Li, Ziyuan, Li, Zonghai, Liang, Hao, Liao, Jiajun, Limphirat, Ayut, Lin, Guey-Lin, Lin, Shengxin, Lin, Tao, Ling, Jiajie, Ling, Xin, Lippi, Ivano, Liu, Caimei, Liu, Fang, Liu, Fengcheng, Liu, Haidong, Liu, Haotian, Liu, Hongbang, Liu, Hongjuan, Liu, Hongtao, Liu, Hui, Liu, Jianglai, Liu, Jiaxi, Liu, Jinchang, Liu, Min, Liu, Qian, Liu, Qin, Liu, Runxuan, Liu, Shenghui, Liu, Shubin, Liu, Shulin, Liu, Xiaowei, Liu, Xiwen, Liu, Xuewei, Liu, Yankai, Liu, Zhen, Lokhov, Alexey, Lombardi, Paolo, Lombardo, Claudio, Loo, Kai, Lu, Chuan, Lu, Haoqi, Lu, Jingbin, Lu, Junguang, Lu, Peizhi, Lu, Shuxiang, Lubsandorzhiev, Bayarto, Lubsandorzhiev, Sultim, Ludhova, Livia, Lukanov, Arslan, Luo, Daibin, Luo, Fengjiao, Luo, Guang, Luo, Jianyi, Luo, Shu, Luo, Wuming, Luo, Xiaojie, Lyashuk, Vladimir, Ma, Bangzheng, Ma, Bing, Ma, Qiumei, Ma, Si, Ma, Xiaoyan, Ma, Xubo, Maalmi, Jihane, Magoni, Marco, Mai, Jingyu, Malyshkin, Yury, Mandujano, Roberto Carlos, Mantovani, Fabio, Mao, Xin, Mao, Yajun, Mari, Stefano M., Marini, Filippo, Martini, Agnese, Mayer, Matthias, Mayilyan, Davit, Mednieks, Ints, Meng, Yue, Meraviglia, Anita, Meregaglia, Anselmo, Meroni, Emanuela, Meyhöfer, David, Miramonti, Lino, Mohan, Nikhil, Montini, Paolo, Montuschi, Michele, Müller, Axel, Nastasi, Massimiliano, Naumov, Dmitry V., Naumova, Elena, Navas-Nicolas, Diana, Nemchenok, Igor, Thi, Minh Thuan Nguyen, Nikolaev, Alexey, Ning, Feipeng, Ning, Zhe, Nunokawa, Hiroshi, Oberauer, Lothar, Ochoa-Ricoux, Juan Pedro, Olshevskiy, Alexander, Orestano, Domizia, Ortica, Fausto, Othegraven, Rainer, Paoloni, Alessandro, Parmeggiano, Sergio, Pei, Yatian, Pelicci, Luca, Peng, Anguo, Peng, Haiping, Peng, Yu, Peng, Zhaoyuan, Perrot, Frédéric, Petitjean, Pierre-Alexandre, Petrucci, Fabrizio, Pilarczyk, Oliver, Rico, Luis Felipe Piñeres, Popov, Artyom, Poussot, Pascal, Previtali, Ezio, Qi, Fazhi, Qi, Ming, Qi, Xiaohui, Qian, Sen, Qian, Xiaohui, Qian, Zhen, Qiao, Hao, Qin, Zhonghua, Qiu, Shoukang, Ranucci, Gioacchino, Rasheed, Reem, Re, Alessandra, Rebii, Abdel, Redchuk, Mariia, Ren, Bin, Ren, Jie, Ricci, Barbara, Rifai, Mariam, Roche, Mathieu, Rodphai, Narongkiat, Romani, Aldo, Roskovec, Bedřich, Ruan, Xichao, Rybnikov, Arseniy, Sadovsky, Andrey, Saggese, Paolo, Sandanayake, Deshan, Sanfilippo, Simone, Sangka, Anut, Sawangwit, Utane, Schever, Michaela, Schwab, Cédric, Schweizer, Konstantin, Selyunin, Alexandr, Serafini, Andrea, Settimo, Mariangela, Sharov, Vladislav, Shaydurova, Arina, Shi, Jingyan, Shi, Yanan, Shutov, Vitaly, Sidorenkov, Andrey, Šimkovic, Fedor, Singhal, Apeksha, Sirignano, Chiara, Siripak, Jaruchit, Sisti, Monica, Smirnov, Mikhail, Smirnov, Oleg, Sogo-Bezerra, Thiago, Sokolov, Sergey, Songwadhana, Julanan, Soonthornthum, Boonrucksar, Sotnikov, Albert, Šrámek, Ondřej, Sreethawong, Warintorn, Stahl, Achim, Stanco, Luca, Stankevich, Konstantin, Steiger, Hans, Steinmann, Jochen, Sterr, Tobias, Stock, Matthias Raphael, Strati, Virginia, Studenikin, Alexander, Su, Jun, Sun, Shifeng, Sun, Xilei, Sun, Yongjie, Sun, Yongzhao, Sun, Zhengyang, Suwonjandee, Narumon, Szelezniak, Michal, Takenaka, Akira, Tang, Jian, Tang, Qiang, Tang, Quan, Tang, Xiao, Hariharan, Vidhya Thara, Theisen, Eric, Tietzsch, Alexander, Tkachev, Igor, Tmej, Tomas, Torri, Marco Danilo Claudio, Tortorici, Francesco, Treskov, Konstantin, Triossi, Andrea, Triozzi, Riccardo, Trzaska, Wladyslaw, Tung, Yu-Chen, Tuve, Cristina, Ushakov, Nikita, Vedin, Vadim, Verde, Giuseppe, Vialkov, Maxim, Viaud, Benoit, Vollbrecht, Cornelius Moritz, von Sturm, Katharina, Vorobel, Vit, Voronin, Dmitriy, Votano, Lucia, Walker, Pablo, Wang, Caishen, Wang, Chung-Hsiang, Wang, En, Wang, Guoli, Wang, Jian, Wang, Jun, Wang, Lu, Wang, Meng, Wang, Ruiguang, Wang, Siguang, Wang, Wei, Wang, Wenshuai, Wang, Xi, Wang, Xiangyue, Wang, Yangfu, Wang, Yaoguang, Wang, Yi, Wang, Yifang, Wang, Yuanqing, Wang, Yuyi, Wang, Zhe, Wang, Zheng, Wang, Zhimin, Watcharangkool, Apimook, Wei, Wei, Wei, Wenlu, Wei, Yadong, Wen, Kaile, Wen, Liangjian, Weng, Jun, Wiebusch, Christopher, Wirth, Rosmarie, Wonsak, Bjoern, Wu, Diru, Wu, Qun, Wu, Yiyang, Wu, Zhi, Wurm, Michael, Wurtz, Jacques, Wysotzki, Christian, Xi, Yufei, Xia, Dongmei, Xiao, Xiang, Xie, Xiaochuan, Xie, Yuguang, Xie, Zhangquan, Xin, Zhao, Xing, Zhizhong, Xu, Benda, Xu, Cheng, Xu, Donglian, Xu, Fanrong, Xu, Hangkun, Xu, Jilei, Xu, Jing, Xu, Meihang, Xu, Yin, Xu, Yu, Yan, Baojun, Yan, Qiyu, Yan, Taylor, Yan, Xiongbo, Yan, Yupeng, Yang, Changgen, Yang, Chengfeng, Yang, Jie, Yang, Lei, Yang, Xiaoyu, Yang, Yifan, Yao, Haifeng, Ye, Jiaxuan, Ye, Mei, Ye, Ziping, Yermia, Frédéric, You, Zhengyun, Yu, Boxiang, Yu, Chiye, Yu, Chunxu, Yu, Guojun, Yu, Hongzhao, Yu, Miao, Yu, Xianghui, Yu, Zeyuan, Yu, Zezhong, Yuan, Cenxi, Yuan, Chengzhuo, Yuan, Ying, Yuan, Zhenxiong, Yue, Baobiao, Zafar, Noman, Zavadskyi, Vitalii, Zeng, Shan, Zeng, Tingxuan, Zeng, Yuda, Zhan, Liang, Zhang, Aiqiang, Zhang, Bin, Zhang, Binting, Zhang, Feiyang, Zhang, Haosen, Zhang, Honghao, Zhang, Jialiang, Zhang, Jiawen, Zhang, Jie, Zhang, Jingbo, Zhang, Jinnan, Zhang, Mohan, Zhang, Peng, Zhang, Qingmin, Zhang, Shiqi, Zhang, Shu, Zhang, Shuihan, Zhang, Siyuan, Zhang, Tao, Zhang, Xiaomei, Zhang, Xin, Zhang, Xuantong, Zhang, Yinhong, Zhang, Yiyu, Zhang, Yongpeng, Zhang, Yu, Zhang, Yuanyuan, Zhang, Yumei, Zhang, Zhenyu, Zhang, Zhijian, Zhao, Jie, Zhao, Rong, Zhao, Runze, Zhao, Shujun, Zheng, Dongqin, Zheng, Hua, Zheng, Yangheng, Zhong, Weirong, Zhou, Jing, Zhou, Li, Zhou, Nan, Zhou, Shun, Zhou, Tong, Zhou, Xiang, Zhu, Jingsen, Zhu, Kangfu, Zhu, Kejun, Zhu, Zhihang, Zhuang, Bo, Zhuang, Honglin, Zong, Liang, Zou, Jiaheng, Züfle, Jan, and Zwickel, Sebastian

Subjects
High Energy Physics - Experiment, Physics - Instrumentation and Detectors
Abstract

The Jiangmen Underground Neutrino Observatory (JUNO), the first multi-kton liquid scintillator detector, which is under construction in China, will have a unique potential to perform a real-time measurement of solar neutrinos well below the few MeV threshold typical for Water Cherenkov detectors. JUNO's large target mass and excellent energy resolution are prerequisites for reaching unprecedented levels of precision. In this paper, we provide estimation of the JUNO sensitivity to 7Be, pep, and CNO solar neutrinos that can be obtained via a spectral analysis above the 0.45 MeV threshold. This study is performed assuming different scenarios of the liquid scintillator radiopurity, ranging from the most opti mistic one corresponding to the radiopurity levels obtained by the Borexino experiment, up to the minimum requirements needed to perform the neutrino mass ordering determination with reactor antineutrinos - the main goal of JUNO. Our study shows that in most scenarios, JUNO will be able to improve the current best measurements on 7Be, pep, and CNO solar neutrino fluxes. We also perform a study on the JUNO capability to detect periodical time variations in the solar neutrino flux, such as the day-night modulation induced by neutrino flavor regeneration in Earth, and the modulations induced by temperature changes driven by helioseismic waves.

Published
2023

85. Enhanced light signal for the suppression of pile-up events in Mo-based bolometers for the $0\nu\beta\beta$ decay search

Author

Ahmine, A., Armatol, A., Bandac, I., Bergé, L., Calvo-Mozota, J. M., Carniti, P., Chapellier, M., Dixon, T., Dumoulin, L., Giuliani, A., Gras, Ph., Ferri, F., Imbert, L., Khalife, H., Loaiza, P., de Marcillac, P., Marnieros, S., Marrache-Kikuchi, C. A., Nones, C., Olivieri, E., de Solòrzano, A. Ortiz, Pessina, G., Poda, D. V., Redon, Th., Scarpaci, J. A., Velàzquez, M., and Zolotorova, A.

Subjects
Physics - Instrumentation and Detectors
Abstract

Random coincidences of events could be one of the main sources of background in the search for neutrino-less double-beta decay of $^{100}$Mo with macro-bolometers, due to their modest time resolution. Scintillating bolometers as those based on Li$_2$MoO$_4$ crystals and employed in the CROSS and CUPID experiments can eventually exploit the coincident fast signal detected in a light detector to reduce this background. However, the scintillation provides a modest signal-to-noise ratio, making difficult a pile-up pulse-shape recognition and rejection at timescales shorter than a few ms. Neganov-Trofimov-Luke assisted light detectors (NTL-LDs) offer the possibility to effectively increase the signal-to-noise ratio, preserving a fast time-response, and enhance the capability of pile-up rejection via pulse shape analysis. In this article we present: a) an experimental work performed with a Li$_2$MoO$_4$ scintillating bolometer, studied in the framework of the CROSS experiment, and utilizing a NTL-LD; b) a simulation method to reproduce, synthetically, randomly coincident two-neutrino double-beta decay events; c) a new analysis method based on a pulse-shape discrimination algorithm capable of providing high pile-up rejection efficiencies. We finally show how the NTL-LDs offer a balanced solution between performance and complexity to reach background index $\sim$$10^{-4}$ counts/keV/kg/year with 280~g Li$_2$MoO$_4$ ($^{100}$Mo enriched) bolometers at 3034 keV, the Q-value of the double-beta decay, and target the goal of a next generation experiment like CUPID.

Published
2023
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86. PointFISH -- learning point cloud representations for RNA localization patterns

Author

Imbert, Arthur, Mueller, Florian, and Walter, Thomas

Subjects
Quantitative Biology - Quantitative Methods, Computer Science - Computer Vision and Pattern Recognition
Abstract

Subcellular RNA localization is a critical mechanism for the spatial control of gene expression. Its mechanism and precise functional role is not yet very well understood. Single Molecule Fluorescence in Situ Hybridization (smFISH) images allow for the detection of individual RNA molecules with subcellular accuracy. In return, smFISH requires robust methods to quantify and classify RNA spatial distribution. Here, we present PointFISH, a novel computational approach for the recognition of RNA localization patterns. PointFISH is an attention-based network for computing continuous vector representations of RNA point clouds. Trained on simulations only, it can directly process extracted coordinates from experimental smFISH images. The resulting embedding allows scalable and flexible spatial transcriptomics analysis and matches performance of hand-crafted pipelines.

Published
2023

87. Topological Imbert–Fedorov shifts in silicene

Author

Akbar, Ali, Shah, Mudasir, and Shah, Muzamil

Abstract

In this paper, we study the topological Imbert–Fedorov (IF) shifts of a light beam reflected from a silicene–substrate system in the presence of an externally applied electric field and circularly polarized beam. Silicene is a topological material and due to the strong spin–orbit interaction has a rich phase diagram. Using the famous Kubo formalism, we derive analytical expressions for the longitudinal and transverse Hall conductivities of silicene. By employing angular spectrum analysis, the analytical expression of the spatial IF shift is obtained. We show that electric field/circularly polarized light beam modulated positive and negative spatial beam shifts can be obtained by tuning the angle of incidence near the Brewster angle and the incident photonic energy in the terahertz regime. Furthermore, we also investigate the IF shifts in different topological phases of the silicene by driving the system through distinct topological quantum phase transitions (TQPTs), i.e., from topologically nontrivial to a semi-metallic state and further to a band insulating state by manipulating the interplay between the electric field and circularly polarized light beam. We believe these results are helpful for developing novel optoelectronic, spintronic, and valleytronic devices and may provide a possible technique for probing Berry curvature, topological Chern numbers, and TQPTs by direct optical measurement.

Published
2022

88. Learning with minimal effort: leveraging in silico labeling for cell and nucleus segmentation

Author

Bonte, Thomas, Philbert, Maxence, Coleno, Emeline, Bertrand, Edouard, Imbert, Arthur, and Walter, Thomas

Subjects
Electrical Engineering and Systems Science - Image and Video Processing, Computer Science - Computer Vision and Pattern Recognition
Abstract

Deep learning provides us with powerful methods to perform nucleus or cell segmentation with unprecedented quality. However, these methods usually require large training sets of manually annotated images, which are tedious and expensive to generate. In this paper we propose to use In Silico Labeling (ISL) as a pretraining scheme for segmentation tasks. The strategy is to acquire label-free microscopy images (such as bright-field or phase contrast) along fluorescently labeled images (such as DAPI or CellMask). We then train a model to predict the fluorescently labeled images from the label-free microscopy images. By comparing segmentation performance across several training set sizes, we show that such a scheme can dramatically reduce the number of required annotations.

Published
2023

89. Demonstration Project of Long-Acting Antiretroviral Therapy in a Diverse Population of People With HIV.

Author

Gandhi, Monica, Hickey, Matthew, Imbert, Elizabeth, Grochowski, Janet, Mayorga-Munoz, Francis, Szumowski, John D, Oskarsson, Jon, Shiels, Mary, Sauceda, John, Salazar, Jorge, Dilworth, Samantha, Nguyen, Janet Q, Glidden, David V, Havlir, Diane V, and Christopoulos, Katerina A

Subjects
Biomedical and Clinical Sciences, Clinical Sciences, Clinical Research, Infectious Diseases, Behavioral and Social Science, Prevention, Mental Health, Minority Health, Sexually Transmitted Infections, Clinical Trials and Supportive Activities, HIV/AIDS, Health Disparities, 6.1 Pharmaceuticals, Infection, Good Health and Well Being, Adult, Male, Humans, Middle Aged, Anti-HIV Agents, Viremia, HIV Infections, Rilpivirine, Cohort Studies, Viral Load, Public Health and Health Services
Abstract

BackgroundIntramuscular cabotegravir (CAB) and rilpivirine (RPV) is the only long-acting antiretroviral therapy (LA-ART) regimen approved for people with HIV (PWH). Long-acting ART holds promise for improving outcomes among populations with barriers to adherence but is only approved for PWH who have virologic suppression with use of oral ART before initiating injectables.ObjectiveTo examine LA-ART in a population of PWH that includes those with viremia.DesignObservational cohort study.SettingUrban academic safety-net HIV clinic.PatientsPublicly insured adults living with HIV with and without viral suppression, high rates of unstable housing, mental illness, and substance use.InterventionDemonstration project of long-acting injectable CAB-RPV.MeasurementsDescriptive statistics summarizing cohort outcomes to date, based on pharmacy team logs and electronic medical record data.ResultsBetween June 2021 and November 2022, 133 PWH at the Ward 86 HIV Clinic were started on LA-ART, 76 of whom had virologic suppression while using oral ART and 57 of whom had viremia. The median age was 46 years (IQR, 25 to 68 years); 117 (88%) were cisgender men, 83 (62%) had non-White race, 56 (42%) were experiencing unstable housing or homelessness, and 45 (34%) had substance use. Among those with virologic suppression, 100% (95% CI, 94% to 100%) maintained suppression. Among PWH with viremia, at a median of 33 days, 54 of 57 had viral suppression, 1 showed the expected 2-log10 reduction in HIV RNA level, and 2 experienced early virologic failure. Overall, 97.5% (CI, 89.1% to 99.8%) were projected to achieve virologic suppression by a median of 33 weeks. The current virologic failure rate of 1.5% in the cohort is similar to that across registrational clinical trials at 48 weeks.LimitationSingle-site study.ConclusionThis project demonstrates the ability of LA-ART to achieve virologic suppression among PWH, including those with viremia and challenges to adherence. Further data on the ability of LA-ART to achieve viral suppression in people with barriers to adherence are needed.Primary funding sourceNational Institutes of Health, City and County of San Francisco, and Health Resources and Services Administration.

Published
2023

90. A first test of CUPID prototypal light detectors with NTD-Ge sensors in a pulse-tube cryostat

Author

Alfonso, K, Armatol, A, Augier, C, Avignone, FT, Azzolini, O, Balata, M, Barabash, AS, Bari, G, Barresi, A, Baudin, D, Bellini, F, Benato, G, Berest, V, Beretta, M, Bettelli, M, Biassoni, M, Billard, J, Boldrini, V, Branca, A, Brofferio, C, Bucci, C, Camilleri, J, Campani, A, Capelli, C, Capelli, S, Cappelli, L, Cardani, L, Carniti, P, Casali, N, Celi, E, Chang, C, Chiesa, D, Clemenza, M, Colantoni, I, Copello, S, Craft, E, Cremonesi, O, Creswick, RJ, Cruciani, A, D'Addabbo, A, D'Imperio, G, Dabagov, S, Dafinei, I, Danevich, FA, De Jesus, M, de Marcillac, P, Dell'Oro, S, Di Domizio, S, Di Lorenzo, S, Dixon, T, Dompé, V, Drobizhev, A, Dumoulin, L, Fantini, G, Faverzani, M, Ferri, E, Ferri, F, Ferroni, F, Figueroa-Feliciano, E, Foggetta, L, Formaggio, J, Franceschi, A, Fu, C, Fu, S, Fujikawa, BK, Gallas, A, Gascon, J, Ghislandi, S, Giachero, A, Gianvecchio, A, Girola, M, Gironi, L, Giuliani, A, Gorla, P, Gotti, C, Grant, C, Gras, P, Guillaumon, PV, Gutierrez, TD, Han, K, Hansen, EV, Heeger, KM, Helis, DL, Huang, HZ, Imbert, L, Johnston, J, Juillard, A, Karapetrov, G, Keppel, G, Khalife, H, Kobychev, VV, Kolomensky, Yu G, Konovalov, SI, Kowalski, R, Langford, T, Lefevre, M, Liu, R, Liu, Y, Loaiza, P, and Ma, L

Subjects
Nuclear and Plasma Physics, Synchrotrons and Accelerators, Physical Sciences, Cryogenic detectors, Gamma detectors, Photon detectors for UV, visible and IR photons, X-ray detectors, Engineering, Nuclear & Particles Physics, Physical sciences
Abstract

CUPID is a next-generation bolometric experiment aiming at searching for neutrinoless double-beta decay with ∼250 kg of isotopic mass of 100Mo. It will operate at ∼10 mK in a cryostat currently hosting a similar-scale bolometric array for the CUORE experiment at the Gran Sasso National Laboratory (Italy). CUPID will be based on large-volume scintillating bolometers consisting of 100Mo-enriched Li2MoO4 crystals, facing thin Ge-wafer-based bolometric light detectors. In the CUPID design, the detector structure is novel and needs to be validated. In particular, the CUORE cryostat presents a high level of mechanical vibrations due to the use of pulse tubes and the effect of vibrations on the detector performance must be investigated. In this paper we report the first test of the CUPID-design bolometric light detectors with NTD-Ge sensors in a dilution refrigerator equipped with a pulse tube in an above-ground lab. Light detectors are characterized in terms of sensitivity, energy resolution, pulse time constants, and noise power spectrum. Despite the challenging noisy environment due to pulse-tube-induced vibrations, we demonstrate that all the four tested light detectors comply with the CUPID goal in terms of intrinsic energy resolution of 100 eV RMS baseline noise. Indeed, we have measured 70-90 eV RMS for the four devices, which show an excellent reproducibility. We have also obtained high energy resolutions at the 356 keV line from a 133Ba source, as good as Ge semiconductor γ detectors in this energy range.

Published
2023

91. Twelve-crystal prototype of Li2MoO4 scintillating bolometers for CUPID and CROSS experiments

Author

Alfonso, K, Armatol, A, Augier, C, Avignone, FT, Azzolini, O, Balata, M, Bandac, IC, Barabash, AS, Bari, G, Barresi, A, Baudin, D, Bellini, F, Benato, G, Berest, V, Beretta, M, Bettelli, M, Biassoni, M, Billard, J, Boldrini, V, Branca, A, Brofferio, C, Bucci, C, Calvo-Mozota, JM, Camilleri, J, Campani, A, Capelli, C, Capelli, S, Cappelli, L, Cardani, L, Carniti, P, Casali, N, Celi, E, Chang, C, Chiesa, D, Clemenza, M, Colantoni, I, Copello, S, Craft, E, Cremonesi, O, Creswick, RJ, Cruciani, A, D'Addabbo, A, D'Imperio, G, Dabagov, S, Dafinei, I, Danevich, FA, De Jesus, M, de Marcillac, P, Dell'Oro, S, Di Domizio, S, Di Lorenzo, S, Dixon, T, Dompé, V, Drobizhev, A, Dumoulin, L, Fantini, G, Faverzani, M, Ferri, E, Ferri, F, Ferroni, F, Figueroa-Feliciano, E, Foggetta, L, Formaggio, J, Franceschi, A, Fu, C, Fu, S, Fujikawa, BK, Gallas, A, Gascon, J, Ghislandi, S, Giachero, A, Gianvecchio, A, Girola, M, Gironi, L, Giuliani, A, Gorla, P, Gotti, C, Grant, C, Gras, P, Guillaumon, PV, Gutierrez, TD, Han, K, Hansen, EV, Heeger, KM, Helis, DL, Huang, HZ, Ianni, A, Imbert, L, Johnston, J, Juillard, A, Karapetrov, G, Keppel, G, Khalife, H, Kobychev, VV, Kolomensky, Yu G, Konovalov, SI, Kowalski, R, Langford, T, Lefevre, M, and Liu, R

Subjects
Nuclear and Plasma Physics, Physical Sciences, Cryogenic detectors, Double-beta decay detectors, Particle identification methods, Scintillators, scintillation and light emission processes, Engineering, Nuclear & Particles Physics, Physical sciences
Abstract

An array of twelve 0.28 kg lithium molybdate (LMO) low-temperature bolometers equipped with 16 bolometric Ge light detectors, aiming at optimization of detector structure for CROSS and CUPID double-beta decay experiments, was constructed and tested in a low-background pulse-tube-based cryostat at the Canfranc underground laboratory in Spain. Performance of the scintillating bolometers was studied depending on the size of phonon NTD-Ge sensors glued to both LMO and Ge absorbers, shape of the Ge light detectors (circular vs. square, from two suppliers), in different light collection conditions (with and without reflector, with aluminum coated LMO crystal surface). The scintillating bolometer array was operated over 8 months in the low-background conditions that allowed to probe a very low, μBq/kg, level of the LMO crystals radioactive contamination by 228Th and 226Ra.

Published
2023

92. CUPID: The Next-Generation Neutrinoless Double Beta Decay Experiment

Author

Alfonso, K, Armatol, A, Augier, C, Avignone, FT, Azzolini, O, Balata, M, Barabash, AS, Bari, G, Barresi, A, Baudin, D, Bellini, F, Benato, G, Beretta, M, Bettelli, M, Biassoni, M, Billard, J, Boldrini, V, Branca, A, Brofferio, C, Bucci, C, Camilleri, J, Campani, A, Capelli, C, Capelli, S, Cappelli, L, Cardani, L, Carniti, P, Casali, N, Celi, E, Chang, C, Chiesa, D, Clemenza, M, Colantoni, I, Copello, S, Craft, E, Cremonesi, O, Creswick, RJ, Cruciani, A, D’Addabbo, A, D’Imperio, G, Dabagov, S, Dafinei, I, Danevich, FA, De Jesus, M, De Marcillac, P, Dell’Oro, S, Domizio, S Di, Lorenzo, S Di, Dixon, T, Dompè, V, Drobizhev, A, Dumoulin, L, Fantini, G, Faverzani, M, Ferri, E, Ferri, F, Ferroni, F, Figueroa-Feliciano, E, Foggetta, L, Formaggio, J, Franceschi, A, Fu, C, Fu, S, Fujikawa, BK, Gallas, A, Gascon, J, Ghislandi, S, Giachero, A, Gianvecchio, A, Gironi, L, Giuliani, A, Gorla, P, Gotti, C, Grant, C, Gras, P, Guillaumon, PV, Gutierrez, TD, Han, K, Hansen, EV, Heeger, KM, Helis, DL, Huang, HZ, Imbert, L, Johnston, J, Juillard, A, Karapetrov, G, Keppel, G, Khalife, H, Kobychev, VV, Kolomensky, Yu G, Konovalov, SI, Kowalski, R, Langford, T, Lefevre, M, Liu, R, Liu, Y, Loaiza, P, Ma, L, Madhukuttan, M, and Mancarella, F

Subjects
Nuclear and Plasma Physics, Particle and High Energy Physics, Physical Sciences, Neutrinoless double beta decay, Bolometers, Low radioactivity, Cryostat, Next-generation bolometric experiment, Mathematical Physics, Classical Physics, Condensed Matter Physics, General Physics, Classical physics, Condensed matter physics
Abstract

CUPID is a next-generation tonne-scale bolometric neutrinoless double beta decay experiment that will probe the Majorana nature of neutrinos and discover lepton number violation in case of observation of this singular process. CUPID will be built on experience, expertise and lessons learned in CUORE and will be installed in the current CUORE infra-structure in the Gran Sasso underground laboratory. The CUPID detector technology, successfully tested in the CUPID-Mo experiment, is based on scintillating bolometers of Li2MoO4 enriched in the isotope of interest 100Mo. In order to achieve its ambitious science goals, the CUPID collaboration aims to reduce the backgrounds in the region of interest by a factor 100 with respect to CUORE. This performance will be achieved by introducing the high efficient α/β discrimination demonstrated by the CUPID-0 and CUPID-Mo experiments, and using a high transition energy double beta decay nucleus such as 100Mo to minimize the impact of the gamma background. CUPID will consist of about 1500 hybrid heat-light detectors for a total isotope mass of 250 kg. The CUPID scientific reach is supported by a detailed and safe background model based on CUORE, CUPID-Mo and CUPID-0 results. The required performances have already been demonstrated and will be presented.

Published
2023

94. Observation of Imbert–Fedorov shift in monolayer MoS_2 via quantum weak measurement

Author

Das, Akash, Mandal, Soumen, and Pradhan, Manik

Abstract

We report the experimental evidence of the Imbert–Fedorov (IF) shift in monolayer MoS_2 for a fundamental Gaussian beam. Using Jones vector formalism, we have shown a novel, to the best of our knowledge, pathway to apply the quantum weak measurement technique for easy and accurate determination of the IF shift. We have revealed the dependence of IF shift over a large range of angles of incidence along with the mode of polarization of the incident light. Our experimental findings via the weak value amplification scheme are in good agreement with the theoretical analysis. The present method is a general one and can also be implemented for other materials to observe such tiny transverse shifts.

Published
2021

97. Magnetic field and Fermi energy modulated quantized Imbert–Fedorov shifts in graphene

Author

Shah, Muzamil, Sajid, Muhammad, and Shah, Mudasir

Abstract

We theoretically investigate the spatial Imbert–Fedorov (SIF) shifts of a light beam reflected from a graphene–substrate system in the presence of an externally applied magnetic field. We impinge a monochromatic light beam of finite width on the surface of a graphene–substrate system and investigate the reflection and transmission coefficients of the beam. We find that the Fermi energy modulated quantized transverse shifts can be achieved in the graphene–substrate system for incident angles in the vicinity of the Brewster angle and frequencies in the terahertz regime. In the case of partial reflection of the light beam, IF shifts acquire moderate magnitudes, while for the case of total internal reflection in the quantum Hall regime, our results show giant negative and positive SIF shifts. Furthermore, we demonstrate that the Brewster angle changes with changing magnetic field and Fermi energy. Our findings are important from the point of view of tuning the IF shifts with magnetic field and Fermi energy conveniently and effectively, which is required to develop new tunable photonic devices in the terahertz regime.

Published
2021

98. Urine Tenofovir Levels Strongly Correlate With Virologic Suppression in Patients With Human Immunodeficiency Virus on Tenofovir Alafenamide-Based Antiretroviral Therapy.

Author

Johnson, Kelly, Okochi, Hideaki, Arreguin, Mireya, Watabe, Joseph, Chattopadhyay, Anindita, Imbert, Elizabeth, Gandhi, Monica, Spinelli, Matthew, Glidden, David, and Hickey, Matthew

Subjects
adherence, point-of-care monitoring, tenofovir alafenamide, viral suppression, Humans, Tenofovir, Anti-HIV Agents, HIV-1, Alanine, HIV Infections, Adenine
Abstract

We found that urine tenofovir (TFV) levels >1500 ng/mL strongly predict virologic suppression among people with human immunodeficiency virus taking tenofovir alafenamide (odds ratio, 5.66; 95% confidence interval, 1.59-20.14; P = .007). This suggests an existing point-of-care assay developed for tenofovir disoproxil fumarate will support adherence monitoring for patients on all TFV-based antiretrovirals.

Published
2023

99. First Demonstration Project of Long-Acting Injectable Antiretroviral Therapy for Persons With and Without Detectable Human Immunodeficiency Virus (HIV) Viremia in an Urban HIV Clinic

Author

Christopoulos, Katerina A, Grochowski, Janet, Mayorga-Munoz, Francis, Hickey, Matthew D, Imbert, Elizabeth, Szumowski, John D, Dilworth, Samantha, Oskarsson, Jon, Shiels, Mary, Havlir, Diane, and Gandhi, Monica

Subjects
Medical Microbiology, Biomedical and Clinical Sciences, Immunology, Infectious Diseases, HIV/AIDS, Evaluation of treatments and therapeutic interventions, 6.1 Pharmaceuticals, Infection, Good Health and Well Being, Male, Humans, Middle Aged, HIV, Anti-HIV Agents, Viremia, HIV Infections, Treatment Outcome, CD4 Lymphocyte Count, Viral Load, AIDS, long-acting antiretroviral therapy, injectable cabotegravir and rilpivirine, viral suppression, engagement in care, Biological Sciences, Medical and Health Sciences, Microbiology, Clinical sciences
Abstract

BackgroundLong-acting injectable antiretroviral therapy (LAI-ART) is approved for treatment-naive or experienced people with human immunodeficiency virus (HIV; PWH) based on trials that only included participants with viral suppression. We performed the first LAI-ART demonstration project to include PWH unable to achieve or maintain viral suppression due to challenges adhering to oral ART.MethodsWard 86 is a large HIV clinic in San Francisco that serves publicly insured and underinsured patients. We started patients on LAI-ART via a structured process of provider referral, multidisciplinary review (MD, RN, pharmacist), and monitoring for on-time injections. Inclusion criteria were willingness to receive monthly injections and a reliable contact method.ResultsBetween June 2021 and April 2022, 51 patients initiated LAI-ART, with 39 receiving at least 2 follow-up injections by database closure (median age, 46 years; 90% cisgender men, 61% non-White, 41% marginally housed, 54% currently using stimulants). Of 24 patients who initiated injections with viral suppression (median CD4 cell count, 706 cells/mm3), 100% (95% confidence interval [CI], 86%-100%) maintained viral suppression. Of 15 patients who initiated injections with detectable viremia (median CD4 cell count, 99 cells/mm3; mean log10 viral load, 4.67; standard deviation, 1.16), 12 (80%; 95% CI, 55%-93%) achieved viral suppression, and the other 3 had a 2-log viral load decline by a median of 22 days.ConclusionsThis small demonstration project of LAI-ART in a diverse group of patients with high levels of substance use and marginal housing demonstrated promising early treatment outcomes, including in those with detectable viremia due to adherence challenges. More data on LAI-ART in hard-to-reach populations are needed.

Published
2023

100. New measurement of double-β decays of Mo100 to excited states of Ru100 with the CUPID-Mo experiment

Author

Augier, C, Barabash, AS, Bellini, F, Benato, G, Beretta, M, Bergé, L, Billard, J, Borovlev, Yu A, Cardani, L, Casali, N, Cazes, A, Chapellier, M, Chiesa, D, Dafinei, I, Danevich, FA, De Jesus, M, Dixon, T, Dumoulin, L, Eitel, K, Ferri, F, Fujikawa, BK, Gascon, J, Gironi, L, Giuliani, A, Grigorieva, VD, Gros, M, Helis, DL, Huang, HZ, Huang, R, Imbert, L, Johnston, J, Juillard, A, Khalife, H, Kleifges, M, Kobychev, VV, Kolomensky, Yu G, Konovalov, SI, Kotila, J, Loaiza, P, Ma, L, Makarov, EP, de Marcillac, P, Mariam, R, Marini, L, Marnieros, S, Navick, X-F, Nones, C, Norman, EB, Olivieri, E, Ouellet, JL, Pagnanini, L, Pattavina, L, Paul, B, Pavan, M, Peng, H, Pessina, G, Pirro, S, Poda, DV, Polischuk, OG, Pozzi, S, Previtali, E, Redon, Th, Rojas, A, Rozov, S, Sanglard, V, Scarpaci, JA, Schmidt, B, Shen, Y, Shlegel, VN, Singh, V, Tomei, C, Tretyak, VI, Umatov, VI, Vagneron, L, Velázquez, M, Welliver, B, Winslow, L, Xue, M, Yakushev, E, Zarytskyy, M, and Zolotarova, AS

Subjects
Nuclear and Plasma Physics, Particle and High Energy Physics, Physical Sciences, Nuclear and plasma physics
Abstract

The CUPID-Mo experiment, located at the Laboratoire Souterrain de Modane (France), was a demonstrator experiment for CUPID. It consisted of an array of 20Li2Mo100O4 (LMO) calorimeters, each equipped with a Ge light detector for particle identification. In this work, we present the result of a search for two-neutrino and neutrinoless double-β decays of Mo100 to the first 0+ and 2+ excited states of Ru100 using the full CUPID-Mo exposure (2.71kgyr of LMO). We measure the half-life of 2νββ decay to the 01+ state as T1/22ν→01+=(7.5±0.8(stat.)-0.3+0.4(syst.))×1020yr. The bolometric technique enables measurement of the electron energies as well as the γ rays from nuclear deexcitation and this allows us to set new limits on the two-neutrino decay to the 21+ state of T1/22ν→21+>4.4×1021yr(90% c.i.) and on the neutrinoless modes of T1/20ν→21+>2.1×1023yr(90% c.i.), T1/20ν→01+>1.2×1023yr(90% c.i.). Information on the electrons' spectral shape is obtained, which allows us to make the first comparison of the single and higher state dominance 2νββ decay models for the 01+ excited state of Ru100.

Published
2023

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