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51. Post-transplant diabetes mellitus and renal cell cancer after renal transplantation

Author

Porrini, Esteban, primary, Montero, Nuria, additional, Díaz, Juan Manuel, additional, Lauzurrica, Ricardo, additional, Rodríguez, Juana Oramas, additional, Torres, Irene Silva, additional, Moreso, Francesc, additional, Cruzado, Josep M, additional, Ruiz, Rocío Benítez, additional, Vilaró, Meritxel Ibernon, additional, Lima, Maria Xixiang Molina, additional, Ramchand, Simran Khemlani, additional, Ruiz, Juan Carlos, additional, Gainza de los Rios, Francisco, additional, Alvarez, Carla Rodríguez, additional, Guindo, María del Carmen de Gracia, additional, Macías, Manuel, additional, Vela, David Bonet, additional, Osuna, Antonio, additional, Bayés-Genís, Beatriz, additional, Sanchez, Cristina Aleman, additional, Ruiz, María del Carmen, additional, Rodríguez, Ana Elena Rodríguez, additional, Rollán, Rosa Domínguez, additional, Rinne, Federico González, additional, Sosa, Alejandro Jiménez, additional, Mallén, Patricia Delgado, additional, Rinne, Ana González, additional, Miranda, Domingo Marrero, additional, and Torres, Armando, additional

Published
2022
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52. Trypanosoma cruzi pathogenicity involves virulence factor expression and upregulation of bioenergetic and biosynthetic pathways

Author

San Francisco, Juan, primary, Astudillo, Constanza, additional, Vega, José Luis, additional, Catalán, Alejandro, additional, Gutiérrez, Bessy, additional, Araya, Jorge E, additional, Zailberger, Anibal, additional, Marina, Anabel, additional, García, Carlos, additional, Sanchez, Nuria, additional, Osuna, Antonio, additional, Vilchez, Susana, additional, Ramírez, Marcel I, additional, Macedo, Janaina, additional, Feijoli, Verónica Santiago, additional, Palmisano, Giuseppe, additional, and González, Jorge, additional

Published
2022
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56. Post-transplant diabetes mellitus and renal cell cancer after renal transplantation.

Author

Porrini, Esteban, Montero, Nuria, Díaz, Juan Manuel, Lauzurrica, Ricardo, Rodríguez, Juana Oramas, Torres, Irene Silva, Moreso, Francesc, Cruzado, Josep M, Ruiz, Rocío Benítez, Vilaró, Meritxel Ibernon, Lima, Maria Xixiang Molina, Ramchand, Simran Khemlani, Ruiz, Juan Carlos, Rios, Francisco Gainza de los, Alvarez, Carla Rodríguez, Guindo, María del Carmen de Gracia, Macías, Manuel, Vela, David Bonet, Osuna, Antonio, and Bayés-Genís, Beatriz

Subjects
RENAL cancer, KIDNEY transplantation, DIABETES, CANCER cells, WATCHFUL waiting, PROSTATE cancer
Abstract

Background Diabetes is a risk factor for cancer in the general population. However, few data are available on the association between post-transplant diabetes mellitus (PTDM) and cancer after transplantation. Methods We analyzed this issue in a Spanish cohort of patients without diabetes before transplantation. PTDM was diagnosed with consensus criteria at 12 months after transplantation and 12 months before the diagnosis of cancer. The association between PTDM and cancer (overall and specific types) was evaluated with regression analysis. Results During a follow-up of 12 years (interquartile range 8–14), 85 cases of 603 developed cancer (829/100 000/year) and 164 (27%) PTDM. The most frequent cancers were renal cell cancer (RCC) n  = 15, 146/cases/100 000/year), lung (n  = 12, 117/cases/100 000/year), colon (n  = 9, 88/cases/100 000/year) and prostate (n  = 9, 88/cases/100 000/year). In logistic regression, PTDM was not associated with cancer. Eight of the 164 patients with PTDM (4.9%) vs 7 of the 439 without PTDM developed RCC (1.6%) (P  = .027). In multivariate analysis, PTDM was independently associated with RCC [odds ratio (OR) 2.92, confidence interval (CI) 1.03–8.27], adjusting for smoking (OR 4.020, 95% CI 1.34–12.02) and other covariates. PTDM was not associated with other types of cancer. Conclusions Patients with PTDM must be considered a population at risk for RCC and accordingly, the subject of active surveillance. [ABSTRACT FROM AUTHOR]

Published
2023
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61. Characterization of Extracellular Vesicles Secreted by a Clinical Isolate of Naegleria fowleri and Identification of Immunogenic Components within Their Protein Cargo

Author

Retana Moreira, Lissette, primary, Steller Espinoza, María Fernanda, additional, Chacón Camacho, Natalia, additional, Cornet-Gomez, Alberto, additional, Sáenz-Arce, Giovanni, additional, Osuna, Antonio, additional, Lomonte, Bruno, additional, and Abrahams Sandí, Elizabeth, additional

Published
2022
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63. Exploring Honeybee Abdominal Anatomy through Micro-CT and Novel Multi-Staining Approaches

Author

De Paula, Jessica Carreira, primary, Doello, Kevin, additional, Mesas, Cristina, additional, Kapravelou, Garyfalia, additional, Cornet-Gómez, Alberto, additional, Orantes, Francisco José, additional, Martínez, Rosario, additional, Linares, Fátima, additional, Prados, Jose Carlos, additional, Porres, Jesus María, additional, Osuna, Antonio, additional, and de Pablos, Luis Miguel, additional

Published
2022
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65. Bioavailability of once-daily tacrolimus formulations used in clinical practice in the management of De Novo kidney transplant recipients: the better study

Author

Fernandez Rivera, Constantino, Calvo Rodriguez, Maria, Poveda JL, Pascual, Julio, Crespo, Marta, Gomez, Gonzalo, Cabello Pelegrin, Sheila, Paul, Javier, Lauzurica, Ricardo, Perez Mir, Monica, Moreso, Francesc, Perello, Manel, Andres, Amado, Gonzalez, Esther, Fernandez, Ana, Mendiluce, Alicia, Fernandez Carbajo, Beatriz, Sanchez Fructuoso, Ana, Calvo, Natividad, Suarez, Alejandro, Bernal Blanco, Gabriel, Osuna, Antonio, Ruiz-Fuentes MC, Melilli, Edoardo, Montero Perez, Nuria, Ramos, Ana, Fernandez, Beatriz, Lopez, Veronica, Hernandez, Domingo, and Better Study

Subjects
Graft Rejection, medicine.medical_specialty, Urology, Biological Availability, Renal function, chemical and pharmacologic phenomena, Tacrolimus, Drug Administration Schedule, Cmin, Pharmacokinetics, Humans, Medicine, Prospective Studies, Adverse effect, tacrolimus, treatment failure, Transplantation, business.industry, renal transplantation, Kidney Transplantation, Transplant Recipients, Discontinuation, Bioavailability, clinical practice, Regimen, business, bioavailability, pharmacokinetics, Immunosuppressive Agents
Abstract

Multicenter, prospective, observational study to compare the relative bioavailability of once-daily tacrolimus formulations in de novo kidney transplant recipients. De novo kidney transplant recipients who started a tacrolimus-based regimen were included 14 days post-transplant and followed up for 6 months. Data from 218 participants were evaluated: 129 in the LCPT group (Envarsus®) and 89 in the PR-Tac (Advagraf®) group. Patients in the LCPT group exhibited higher relative bioavailability (Cmin /total daily dose [TDD]) vs PR-Tac (61% increase; p

Published
2022

66. Additional file 5 of Molecular detection of Leishmania infantum in rats and sand flies in the urban sewers of Barcelona, Spain

Author

Galán-Puchades, María Teresa, Solano, Jennifer, González, Gloria, Osuna, Antonio, Pascual, Jordi, Bueno-Marí, Rubén, Franco, Sandra, Peracho, Víctor, Montalvo, Tomás, and Fuentes, Màrius V.

Subjects
parasitic diseases
Abstract

Additional file 5: Rat ears. Figure S7. Standard curve of L. infantum DNA. Standard curve obtained from a series of dilutions of L. infantum DNA (108 to 101 parasites). Each point was tested in triplicate. Slope = -3.47; efficacy = 94.1%; R2 = 0.998. Figure S8. Amplification curves. The plot showing the dilution of DNA concentrations (8 to 8 × 10-7 ng).

Published
2022
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67. Additional file 4 of Molecular detection of Leishmania infantum in rats and sand flies in the urban sewers of Barcelona, Spain

Author

Galán-Puchades, María Teresa, Solano, Jennifer, González, Gloria, Osuna, Antonio, Pascual, Jordi, Bueno-Marí, Rubén, Franco, Sandra, Peracho, Víctor, Montalvo, Tomás, and Fuentes, Màrius V.

Subjects
parasitic diseases
Abstract

Additional file 4: Rat spleens. Figure S5. Standard curve of L. infantum DNA. Standard curve obtained from a series of dilutions of L. infantum DNA (108 to 101 parasites). Each point was tested in triplicate. Slope = -3.367; efficacy = 98.2%; R2 = 0.998. Figure S6. Amplification curves. The plot showing the dilution of DNA concentrations (8–8 × 10-7 ng).

Published
2022
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68. Additional file 3 of Molecular detection of Leishmania infantum in rats and sand flies in the urban sewers of Barcelona, Spain

Author

Galán-Puchades, María Teresa, Solano, Jennifer, González, Gloria, Osuna, Antonio, Pascual, Jordi, Bueno-Marí, Rubén, Franco, Sandra, Peracho, Víctor, Montalvo, Tomás, and Fuentes, Màrius V.

Abstract

Additional file 3: Sand flies. Figure S3. Standard curve of L. infantum DNA. Standard curve obtained from serial dilutions of L. infantum DNA (108 to 101 parasites). Each point was tested in triplicate. Slope = — 3.70; efficacy = 98 %; R2 = 0.991. Figure S4. Amplification curves. The plot showing the dilution of DNA concentrations (8 to 8 × 10-7 ng).

Published
2022
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69. Additional file 1 of Molecular detection of Leishmania infantum in rats and sand flies in the urban sewers of Barcelona, Spain

Author

Galán-Puchades, María Teresa, Solano, Jennifer, González, Gloria, Osuna, Antonio, Pascual, Jordi, Bueno-Marí, Rubén, Franco, Sandra, Peracho, Víctor, Montalvo, Tomás, and Fuentes, Màrius V.

Abstract

Additional file 1: Sequence of the 3'-UTR region. Figure S1. The 3'-UTR region of the HSP70 gene was amplified with primers 70-IR-D (5'- CCAAGGTCGAGGAGGAGGTCGAC TA-3') and 70-IR-M (5'-ACGGGTAGGGGGGGAGGAAAGA-3').

Published
2022
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70. Additional file 2 of Molecular detection of Leishmania infantum in rats and sand flies in the urban sewers of Barcelona, Spain

Author

Galán-Puchades, María Teresa, Solano, Jennifer, González, Gloria, Osuna, Antonio, Pascual, Jordi, Bueno-Marí, Rubén, Franco, Sandra, Peracho, Víctor, Montalvo, Tomás, and Fuentes, Màrius V.

Abstract

Additional file 2: Phylogenetic analysis. Figure S2. Phylogenetic tree using 3'-UTR sequences of the HSP70 gene.

Published
2022
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73. Clinical evolution of post-transplant diabetes mellitus

Author

Porrini, Esteban L., Díaz, Jose M., Moreso, Francisco, Delgado Mallén, Patricia I., Silva Torres, Irene, Ibernon, Meritxell, Bayés-Genís, Beatriz, Benitez-Ruiz, Rocío, Lampreabe, Ildefonso, Lauzurrica, Ricardo, Osorio, Jose M., Osuna, Antonio, Domínguez-Rollán, Rosa, Ruiz, Juan C., Jiménez-Sosa, Alejandro, González-Rinne, Ana, Marrero-Miranda, Domingo, Macía, Manuel, García, Javier, and Torres, Armando

Published
2016
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74. Trypanosoma cruzi I genotypes in different geographical regions and transmission cycles based on a microsatellite motif of the intergenic spacer of spliced-leader genes

Author

Cura, Carolina I., Mejía-Jaramillo, Ana M., Duffy, Tomás, Burgos, Juan M., Rodriguero, Marcela, Cardinal, Marta V., Kjos, Sonia, Gurgel-Gonçalves, Rodrigo, Blanchet, Denis, De Pablos, Luis M., Tomasini, Nicolás, da Silva, Alexandre, Russomando, Graciela, Cuba, Cesar A. Cuba, Aznar, Christine, Abate, Teresa, Levin, Mariano J., Osuna, Antonio, Gürtler, Ricardo E., Diosque, Patricio, Solari, Aldo, Triana-Chávez, Omar, and Schijman, Alejandro G.

Published
2010
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77. La perspectiva de las cuidadoras informales sobre la atención domiciliaria: un estudio cualitativo con ayuda de un programa informático

Author

Prieto Rodríguez Mª Ángeles, Gil García Eugenia, Heierle Valero Cristina, and Frías Osuna Antonio

Subjects
Atención domiciliaria, Satisfacción de usuarios, Calidad percibida, Paciente terminal, Ancianos dependientes, Cirugía ambulatoria, Métodos cualitativos, Medicine, Public aspects of medicine, RA1-1270
Abstract

Fundamento. Existe en nuestro país un vivo debate sobre los modelos de atención domiciliaria que se deben desarrollar. Este estudio pretende conocer cómo perciben la calidad de la atención domiciliaria los cuidadores familiares de pacientes con cáncer en fase terminal, ancianos con demencia y personas intervenidas en programadas de cirugía mayor ambulatoria. Métodos: Estudio cualitativo de tipo fenomenológico basado en grupos de discusión (9), grupos triangulares (5) y entrevistas en profundidad (22). El estudio se realizó en Andalucía, durante los años 1999 y 2000. Los sujetos del estudio son los cuidadores principales de los pacientes que reciben atención domiciliaria desde los centros de salud. La información se ha analizado mediante análisis de contenido apoyado por el software NUDIST- 4. Las variables de análisis han sido las del modelo SERVQUAL. Resultados. Para las cuidadoras de pacientes con cáncer las dimensiones más importantes de la calidad de la atención domiciliaria son la Capacidad de Respuesta y la Accesibilidad. Elementos negativos que perjudican la accesibilidad son: la falta de cobertura de atención domiciliaria fuera del horario normal, la dificultad de contactar por teléfono, la tardanza en acudir y las visitas sólo a demanda. Las cuidadoras de pacientes intervenidos en cirugía mayor ambulatoria quieren Seguridad y la Fiabilidad. Las cuidadoras de ancianos con demencia consideran prioritario que se les proporcionen los materiales que necesitan para cuidar al enfermo. Conclusiones: Las expectativas de cuidadores y pacientes varían en función del problema de salud. Por lo tanto, las características de la atención domiciliaria tendrán que variar también en función de ello. Se hace necesario un modelo flexible que sea capaz de adaptarse a las necesidades de los diferentes tipos de pacientes y las circunstancias también distintas de sus cuidadores familiares.

Published
2002

91. Lactancia materna

Author

Velasco-Juez, Casilda, primary, Pulido-Soto, Adoración, additional, and Frías Osuna, Antonio, additional

Published
2014
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92. Colaboradores

Author

Aliaga Sánchez, D.ª María del Carmen, primary, Baudet Montilla, D. Inocente, additional, Cabañero Martínez, María José, additional, Cadaval García, D.ª María Dolores, additional, Carranza Miranda, D.ª Eva María, additional, Casabona Martínez, Isabel, additional, Casado Lollano, D.ª Amparo, additional, Casas Martínez, Francisca, additional, Cerón Inglés, D. Francisco, additional, Cibanal Juan, Luis, additional, Domínguez Santamaría, Juan Mario, additional, Duarte Climents, D. Gonzalo, additional, Fernández Salazar, D. Serafín, additional, Francisco del Rey, Cristina, additional, Frías Osuna, Antonio, additional, Fuster Pérez, D.ª Marina, additional, Gabaldón Bravo, Eva María, additional, García Aboín, D. Óscar, additional, García Fernández, Francisco Pedro, additional, García González, D.ª Concepción, additional, Grande Gascón, María Luisa, additional, Granero Moya, D.ª Juana María, additional, Gutiérrez Gascón, D. José, additional, Heierle Valero, Cristina, additional, Huertas Linero, D.ª Cristina, additional, Hurtado Sánchez, José Antonio, additional, Lillo Crespo, Manuel, additional, López Casanova, D. Pablo, additional, López Samaniego, Luz, additional, Martínez Riera, José Ramón, additional, de Mendiolagoitia Cortina, D. Luis Antonio, additional, Millán Cobo, D. Martín David, additional, Millán Cobo, D.ª María del Sol, additional, Moreno Cámara, D.ª Sara, additional, Muñoz Mendoza, Carmen Luz, additional, Noreña Peña, Ana Lucía, additional, Oltra Rodríguez, D. Enrique, additional, Palomino Moral, Pedro Ángel, additional, Pancorbo-Hidalgo, Pedro L., additional, Paz Jiménez, D. Jesús de la, additional, Peña Rodríguez, D. Antonio, additional, Pérez Mora, D.ª María Jesús, additional, Pérez Pont, D.ª Inmaculada, additional, Perpiñá Galvañ, Juana, additional, del Pino Casado, D. Benito, additional, del Pino Casado, Rafael, additional, Pulido-Soto, D.ª Adoración, additional, Ramos Morcillo, D. Antonio Jesús, additional, Ramos-Pichardo, Juan Diego, additional, Roces Camino, D. José Ramón, additional, Rodríguez Torres, D.ª María del Carmen, additional, Ruiz Nieto, D. Valentín, additional, Saavedra Llobregat, D.ª María Dolores, additional, Sánchez-García, D.ª Inmaculada, additional, Sánchez Gómez, D.ª Begoña, additional, Sanjuán Quiles, Ángela, additional, Solano Ruiz, María del Carmen, additional, Soldevilla Ágreda, Javier, additional, Tirado Darder, D. Juan José, additional, Valero Marco, D. Antonio Vicente, additional, Velasco-Alvárez, D.ª María Luisa, additional, Velasco-Juez, D.ª Casilda, additional, and Verdú Soriano, José, additional

Published
2014
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94. Demografía y salud

Author

del Pino Casado, Rafael, primary, Frías Osuna, Antonio, additional, and Palomino Moral, Pedro Ángel, additional

Published
2014
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95. Enfermedad de Alzheimer

Author

Moreno Cámara, Sara, primary, Palomino Moral, Pedro Ángel, additional, Frías Osuna, Antonio, additional, and del Pino Casado, Rafael, additional

Published
2014
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97. Estilos de vida

Author

del Pino Casado, Rafael, primary, Frías Osuna, Antonio, additional, and Palomino Moral, Pedro Ángel, additional

Published
2014
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98. Calidad, evaluación y mejora

Author

Frías Osuna, Antonio, primary, Pulido-Soto, Adoración, additional, del Pino Casado, Rafael, additional, and Palomino Moral, Pedro Ángel, additional

Published
2014
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100. Calidad asistencial: concepto

Author

Frías Osuna, Antonio, primary, del Pino Casado, Rafael, additional, Pulido-Soto, Adoración, additional, and Palomino Moral, Pedro Ángel, additional

Published
2014
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