64 results on '"Oh, Dae Jong"'
Search Results
52. Magnetic Resonance Imaging Texture of Medial Pulvinar in Dementia with Lewy Bodies
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Tak, Kayeong, primary, Lee, Subin, additional, Choi, Euna, additional, Suh, Seung Wan, additional, Oh, Dae Jong, additional, Moon, Woori, additional, Kim, Hye Sung, additional, Byun, Seonjeong, additional, Bae, Jong Bin, additional, Han, Ji Won, additional, Kim, Jae Hyoung, additional, and Kim, Ki Woong, additional
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- 2020
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53. Supplementary_table – Supplemental material for Epidemiological characteristics of subsyndromal depression in late life
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Oh, Dae Jong, Han, Ji Won, Kim, Tae Hui, Kwak, Kyung Phil, Kim, Bong Jo, Kim, Shin Gyeom, Kim, Jeong Lan, Moon, Seok Woo, Park, Joon Hyuk, Ryu, Seung-Ho, Youn, Jong Chul, Lee, Dong Young, Lee, Dong Woo, Lee, Seok Bum, Lee, Jung Jae, Jhoo, Jin Hyeong, and Kim, Ki Woong
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FOS: Psychology ,FOS: Clinical medicine ,170199 Psychology not elsewhere classified ,110319 Psychiatry (incl. Psychotherapy) ,Neuroscience - Abstract
Supplemental material, Supplementary_table for Epidemiological characteristics of subsyndromal depression in late life by Dae Jong Oh, Ji Won Han, Tae Hui Kim, Kyung Phil Kwak, Bong Jo Kim, Shin Gyeom Kim, Jeong Lan Kim, Seok Woo Moon, Joon Hyuk Park, Seung-Ho Ryu, Jong Chul Youn, Dong Young Lee, Dong Woo Lee, Seok Bum Lee, Jung Jae Lee, Jin Hyeong Jhoo and Ki Woong Kim in Australian & New Zealand Journal of Psychiatry
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- 2019
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54. Chronic subsyndromal depression and risk of dementia in older adults.
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Oh, Dae Jong, Han, Ji Won, Bae, Jong Bin, Kim, Tae Hui, Kwak, Kyung Phil, Kim, Bong Jo, Kim, Shin Gyeom, Kim, Jeong Lan, Moon, Seok Woo, Park, Joon Hyuk, Ryu, Seung-Ho, Youn, Jong Chul, Lee, Dong Young, Lee, Dong Woo, Lee, Seok Bum, Lee, Jung Jae, Jhoo, Jin Hyeong, and Kim, Ki Woong
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DEMENTIA risk factors , *CONFIDENCE intervals , *MILD cognitive impairment , *RISK assessment , *MENTAL depression , *STATISTICAL sampling , *LONGITUDINAL method , *PROPORTIONAL hazards models , *OLD age - Abstract
Objectives: Subsyndromal depression is prevalent and associated with poor outcomes in late life, but its effect on the risk of dementia has barely been investigated. This study is aimed to investigate the effect of subsyndromal depression on dementia risk in cognitively normal older adults and patients with mild cognitive impairment. Methods: Data were collected from a nationwide, population-based, prospective cohort study on a randomly sampled Korean elderly population aged 60 years or older, which has been followed every 2 years. Using 6-year follow-up data of 4456 non-demented elderly, the authors examined the risk of dementia associated with late-onset subsyndromal depression using multivariate Cox proportional hazard models. After standardized diagnostic interviews, subsyndromal depression and dementia were diagnosed by the operational diagnostic criteria and Diagnostic and Statistical Manual of Mental Disorders, 4th edition criteria, respectively. Results: Subsyndromal depression tripled the risk of dementia in non-demented elderly individuals (hazard ratio = 3.02, 95% confidence interval = [1.56, 5.85], p < 0.001). In subgroup analyses, subsyndromal depression was associated with the risk of dementia in cognitively normal participants only (hazard ratio = 4.59, 95% confidence interval = [1.20, 17.54], p = 0.026); chronic/recurrent subsyndromal depression with increasing severity during the follow-up period was associated with the risk of dementia (hazard ratio = 15.34, 95% confidence interval = [4.19, 56.18], p < 0.001). Conclusion: Late-onset subsyndromal depression is a potential predictor of incident dementia when it is chronic or recurrent with increasing severity in cognitively normal older adults. [ABSTRACT FROM AUTHOR]
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- 2021
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55. Executive dysfunction and risk of suicide in older adults: a population-based prospective cohort study.
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Dae Jong Oh, Ji Won Han, Jong Bin Bae, Tae Hui Kim, Kyung Phil Kwak, Bong Jo Kim, Shin Gyeom Kim, Jeong Lan Kim, Seok Woo Moon, Joon Hyuk Park, Seung-Ho Ryu, Jong Chul Youn, Dong Young Lee, Dong Woo Lee, Seok Bum Lee, Jung Jae Lee, Jin Hyeong Jhoo, Ki Woong Kim, Oh, Dae Jong, and Han, Ji Won
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SUICIDE risk factors ,OLDER people ,SUICIDE ,COHORT analysis ,APOLIPOPROTEIN E ,SUICIDE victims ,PROBLEM-solving therapy - Abstract
Objective: It is uncertain what factors increases the risk of suicide in older adults without depression, and it is unknown whether executive dysfunction (ED) is one of those factors. We aimed to examine the effect of ED on the risk of suicide in non-demented older adults without depression.Methods: In an ongoing population-based prospective cohort of Korean older adults, we identified suicide using the National Mortality Database and suicidal ideation or attempt (SIA) based on the Korean version of the Mini International Neuropsychiatric Interview. We defined ED as performing below -1.5 SD of age-adjusted, gender-adjusted and education-adjusted norms in any of following tests: Frontal Assessment Battery, Trail Making Test A, Digit Span Test or Verbal Fluency Test.Results: The mean age of the 4791 participants at baseline was 69.7 (SD 6.4) years, and 57.1% of them were women (mean follow-up duration=4.9 years). ED at baseline increased the risk of suicide by about seven times (HR 7.20, 95% CI 1.84 to 28.12, p=0.005) but did not change the risk of SIA. However, cognitive impairment without ED did not change the risks of suicide and SIA. In participants with ED, being aged 75 years or above, living alone, and having a low socioeconomic status were associated with the risk of suicide.Conclusion: ED is a strong risk factor of late life suicide independent from depression, particularly in very old adults living in disadvantaged environments. [ABSTRACT FROM AUTHOR]- Published
- 2021
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56. Epidemiological characteristics of subsyndromal depression in late life
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Oh, Dae Jong, primary, Han, Ji Won, additional, Kim, Tae Hui, additional, Kwak, Kyung Phil, additional, Kim, Bong Jo, additional, Kim, Shin Gyeom, additional, Kim, Jeong Lan, additional, Moon, Seok Woo, additional, Park, Joon Hyuk, additional, Ryu, Seung-Ho, additional, Youn, Jong Chul, additional, Lee, Dong Young, additional, Lee, Dong Woo, additional, Lee, Seok Bum, additional, Lee, Jung Jae, additional, Jhoo, Jin Hyeong, additional, and Kim, Ki Woong, additional
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- 2019
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57. Epidemiological characteristics of subsyndromal depression in late life.
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Oh, Dae Jong, Han, Ji Won, Kim, Tae Hui, Kwak, Kyung Phil, Kim, Bong Jo, Kim, Shin Gyeom, Kim, Jeong Lan, Moon, Seok Woo, Park, Joon Hyuk, Ryu, Seung-Ho, Youn, Jong Chul, Lee, Dong Young, Lee, Dong Woo, Lee, Seok Bum, Lee, Jung Jae, Jhoo, Jin Hyeong, and Kim, Ki Woong
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DIAGNOSIS of mental depression , *MENTAL depression risk factors , *AGE distribution , *CONFIDENCE intervals , *MENTAL depression , *EXERCISE , *GERIATRIC psychiatry , *INTERVIEWING , *LONGITUDINAL method , *CLASSIFICATION of mental disorders , *SEX distribution , *SLEEP , *LOGISTIC regression analysis , *SOCIAL support , *SOCIOECONOMIC factors , *INDEPENDENT living - Abstract
Objectives: Subsyndromal depression is prevalent and associated with poor outcomes in late life, but its epidemiological characteristics have barely been investigated. The aim of this prospective cohort study is to compare the prevalence, incidence and risk factors of subsyndromal depression with those of syndromal depression including major and minor depressive disorders in community-dwelling elderly individuals. Methods: In a nationwide community-based study of randomly sampled Korean elderly population aged 60 years or older (N = 6640), depression was assessed with standardized diagnostic interviews. At baseline and at 2-year and 4-year follow-ups, the authors diagnosed subsyndromal depression by the operational criteria and syndromal depression by the Diagnostic and Statistical Manual of Mental Disorders (4th ed.) diagnostic criteria. Multivariate logistic regression analyses were conducted to identify the risk factors for incident depression. Results: The age- and gender-adjusted prevalence rate of subsyndromal depression was 9.24% (95% confidence interval = [8.54, 9.93]), which was 2.4-fold higher than that of syndromal depression. The incidence rate of subsyndromal depression was 21.70 per 1000 person-years (95% confidence interval = [19.29, 24.12]), which was fivefold higher than that of syndromal depression. The prevalence to incidence ratio of subsyndromal depression was about half that of syndromal depression. The risk for subsyndromal depression was associated with female gender, low socioeconomic status, poor social support and poor sleep quality, while that of syndromal depression was associated with old age and less exercise. Conclusion: Subsyndromal depression should be validated as a clinical diagnostic entity, at least in late life, since it has epidemiological characteristics different from those of syndromal depression. [ABSTRACT FROM AUTHOR]
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- 2020
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58. An Analysis of the Relationship between Mood State, Job Stress and Job Effectiveness of Office Workers’ Kendo Participants
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Oh, Dae-Jong, primary, Lee, Yang-Joo, additional, and Ha, Sang-Won, additional
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- 2018
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59. Association of Up-Regulated Plasma Adiponectin With Risk of Incident Depression in a Community-Dwelling Elderly Population
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Oh, Dae Jong, primary, Han, Ji Won, additional, Min, Beom Jun, additional, Jeong, Hyun-Ghang, additional, Kim, Tae Hui, additional, Choi, Sung Hee, additional, Lim, Soo, additional, Lee, Jung Jae, additional, Park, Joon Hyuk, additional, Lee, Seok Bum, additional, Park, Young Joo, additional, Jang, Hak Chul, additional, and Kim, Ki Woong, additional
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- 2018
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60. Epidemiological Characteristics of Subsyndromal Depression in Late Life
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Oh, Dae Jong, primary, Han, Ji Won, additional, Kim, Tae Hui, additional, Kwak, Kyung Phil, additional, Kim, Bong Jo, additional, Kim, Shin Gyeom, additional, Kim, Jeong Lan, additional, Moon, Seok Woo, additional, Park, Joon Hyuk, additional, Ryu, Seung-Ho, additional, Youn, Jong Chul, additional, Lee, Dong Young, additional, Lee, Dong Woo, additional, Lee, Seok Bum, additional, Lee, Jung Jae, additional, Jhoo, Jin Hyeong, additional, and Kim, Ki Woong, additional
- Published
- 2018
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61. Overview of the Unites States Air Force Suicide Prevention Program and Implications for Korean Armed Forces
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Oh, Dae Jong, primary, Baik, Myung Jae, additional, and Cho, Soo-Churl, additional
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- 2017
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62. Masticatory Function, Sex, and Risk of Dementia Among Older Adults: A Population-Based Cohort Study.
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Oh DJ, Han JW, Kim JS, Kim TH, Kwak KP, Kim BJ, Kim SG, Kim JL, Moon SW, Park JH, Ryu SH, Youn JC, Lee DY, Lee DW, Lee SB, Lee JJ, Jhoo JH, and Kim KW
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- Humans, Male, Female, Aged, Prospective Studies, Risk Factors, Middle Aged, Cohort Studies, Proportional Hazards Models, Sex Factors, Cognition physiology, Cognitive Dysfunction, Aged, 80 and over, Mastication, Magnetic Resonance Imaging, Dementia, Brain diagnostic imaging, Brain pathology, Alzheimer Disease
- Abstract
Background: A decline in masticatory function may indicate brain dysfunction related to dementia, but the relationship between masticatory function and dementia risk remains unclear. This study aimed to investigate whether masticatory function is associated with the risk of cognitive decline and dementia., Methods: Data were obtained from the nationwide prospective cohort study of randomly sampled community-dwelling Koreans aged ≥ 60 years. The 5,064 non-demented participants, whose number of chewing cycles per bite was assessed by clinical interview, were followed for 8 years with biennial assessments of cognitive performance and clinical diagnoses of all-cause dementia and Alzheimer's disease (AD). Structural brain magnetic resonance imaging was collected from a subset of cohort participants and their spouses for imaging analyses., Results: Males who chewed ≥ 30 cycles/bite had faster decline in global cognition and memory function and were at higher risk for incident all-cause dementia (hazard ratio [HR], 2.91; 95% confidence interval [CI], 1.18-7.18) and AD (HR, 3.22; 95% CI, 1.14-9.11) compared to males with less than 10 cycles/bite. Additionally, increased chewing cycles in males were associated with reduced brain volume, particularly in regions involved in compensatory cognitive control of mastication. There was no significant association between chewing cycles and the risk of dementia or brain volume in females., Conclusion: Older men who frequently chew their meals could be considered a notable population at risk for dementia who should be carefully assessed for their cognitive trajectories., Competing Interests: The authors have no potential conflicts of interest to disclose., (© 2024 The Korean Academy of Medical Sciences.)
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- 2024
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63. Blood Pressure, Antihypertensive Use, and Late-Life Alzheimer and Non-Alzheimer Dementia Risk: An Individual Participant Data Meta-Analysis.
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Lennon MJ, Lipnicki DM, Lam BCP, Crawford JD, Schutte AE, Peters R, Rydberg-Sterner T, Najar J, Skoog I, Riedel-Heller SG, Röhr S, Pabst A, Lobo A, De-la-Cámara C, Lobo E, Lipton RB, Katz MJ, Derby CA, Kim KW, Han JW, Oh DJ, Rolandi E, Davin A, Rossi M, Scarmeas N, Yannakoulia M, Dardiotis T, Hendrie HC, Gao S, Carriere I, Ritchie K, Anstey KJ, Cherbuin N, Xiao S, Yue L, Li W, Guerchet M, Preux PM, Aboyans V, Haan MN, Aiello A, Scazufca M, and Sachdev PS
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- Humans, Aged, Male, Female, Aged, 80 and over, Longitudinal Studies, Risk Factors, Alzheimer Disease epidemiology, Alzheimer Disease drug therapy, Antihypertensive Agents therapeutic use, Hypertension drug therapy, Hypertension epidemiology, Hypertension complications, Blood Pressure drug effects, Dementia epidemiology
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Background and Objectives: Previous randomized controlled trials and longitudinal studies have indicated that ongoing antihypertensive use in late life reduces all-cause dementia risk, but the specific impact on Alzheimer dementia (AD) and non-AD risk remains unclear. This study investigates whether previous hypertension or antihypertensive use modifies AD or non-AD risk in late life and the ideal blood pressure (BP) for risk reduction in a diverse consortium of cohort studies., Methods: This individual participant data meta-analysis included community-based longitudinal studies of aging from a preexisting consortium. The main outcomes were risk of developing AD and non-AD. The main exposures were hypertension history/antihypertensive use and baseline systolic BP/diastolic BP. Mixed-effects Cox proportional hazards models were used to assess risk and natural splines were applied to model the relationship between BP and the dementia outcomes. The main model controlled for age, age
2 , sex, education, ethnoracial group, and study cohort. Supplementary analyses included a fully adjusted model, an analysis restricting to those with >5 years of follow-up and models that examined the moderating effect of age, sex, and ethnoracial group., Results: There were 31,250 participants from 14 nations in the analysis (41% male) with a mean baseline age of 72 (SD 7.5, range 60-110) years. Participants with untreated hypertension had a 36% (hazard ratio [HR] 1.36, 95% CI 1.01-1.83, p = 0.0406) and 42% (HR 1.42, 95% CI 1.08-1.87, p = 0.0135) increased risk of AD compared with "healthy controls" and those with treated hypertension, respectively. Compared with "healthy controls" both those with treated (HR 1.29, 95% CI 1.03-1.60, p = 0.0267) and untreated hypertension (HR 1.69, 95% CI 1.19-2.40, p = 0.0032) had greater non-AD risk, but there was no difference between the treated and untreated groups. Baseline diastolic BP had a significant U-shaped relationship ( p = 0.0227) with non-AD risk in an analysis restricted to those with 5-year follow-up, but otherwise there was no significant relationship between baseline BP and either AD or non-AD risk., Discussion: Antihypertensive use was associated with decreased AD but not non-AD risk throughout late life. This suggests that treating hypertension throughout late life continues to be crucial in AD risk mitigation. A single measure of BP was not associated with AD risk, but DBP may have a U-shaped relationship with non-AD risk over longer periods in late life.- Published
- 2024
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64. Lifestyle and incident dementia: A COSMIC individual participant data meta‐analysis.
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Van Asbroeck S, Köhler S, van Boxtel MPJ, Lipnicki DM, Crawford JD, Castro-Costa E, Lima-Costa MF, Blay SL, Shifu X, Wang T, Yue L, Lipton RB, Katz MJ, Derby CA, Guerchet M, Preux PM, Mbelesso P, Norton J, Ritchie K, Skoog I, Najar J, Sterner TR, Scarmeas N, Yannakoulia M, Dardiotis T, Rolandi E, Davin A, Rossi M, Gureje O, Ojagbemi A, Bello T, Kim KW, Han JW, Oh DJ, Trompet S, Gussekloo J, Riedel-Heller SG, Röhr S, Pabst A, Shahar S, Rivan NFM, Singh DKA, Jacobsen E, Ganguli M, Hughes T, Haan M, Aiello AE, Ding D, Zhao Q, Xiao Z, Narazaki K, Chen T, Chen S, Ng TP, Gwee X, Gao Q, Brodaty H, Trollor J, Kochan N, Lobo A, Santabárbara J, Gracia-Garcia P, Sachdev PS, and Deckers K
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- Humans, Male, Female, Risk Factors, Aged, Prospective Studies, Incidence, Dementia epidemiology, Life Style
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Introduction: The LIfestyle for BRAin Health (LIBRA) index yields a dementia risk score based on modifiable lifestyle factors and is validated in Western samples. We investigated whether the association between LIBRA scores and incident dementia is moderated by geographical location or sociodemographic characteristics., Methods: We combined data from 21 prospective cohorts across six continents (N = 31,680) and conducted cohort-specific Cox proportional hazard regression analyses in a two-step individual participant data meta-analysis., Results: A one-standard-deviation increase in LIBRA score was associated with a 21% higher risk for dementia. The association was stronger for Asian cohorts compared to European cohorts, and for individuals aged ≤75 years (vs older), though only within the first 5 years of follow-up. No interactions with sex, education, or socioeconomic position were observed., Discussion: Modifiable risk and protective factors appear relevant for dementia risk reduction across diverse geographical and sociodemographic groups., Highlights: A two-step individual participant data meta-analysis was conducted. This was done at a global scale using data from 21 ethno-regionally diverse cohorts. The association between a modifiable dementia risk score and dementia was examined. The association was modified by geographical region and age at baseline. Yet, modifiable dementia risk and protective factors appear relevant in all investigated groups and regions., (© 2024 The Authors. Alzheimer's & Dementia published by Wiley Periodicals LLC on behalf of Alzheimer's Association.)
- Published
- 2024
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