99 results on '"Niyonsenga, Theo"'
Search Results
52. Improving Birth Preparedness and Complication Readiness in Rural India Through an Integrated Microfinance and Health Literacy Program: Evidence from a Quasi-Experimental Study
- Author
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ahmad, danish, primary, Mohanty, Itismita, additional, and Niyonsenga, Theo, additional
- Published
- 2020
- Full Text
- View/download PDF
53. Optimizing the measurement of comorbidity for a South Australian colorectal cancer population using administrative data
- Author
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Pule, Lettie, primary, Buckley, Elizabeth, additional, Niyonsenga, Theo, additional, and Roder, David, additional
- Published
- 2019
- Full Text
- View/download PDF
54. A Longitudinal Analysis of Mental and General Health Status of Informal Carers in Australia
- Author
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Mohanty, Itismita, primary and Niyonsenga, Theo, additional
- Published
- 2019
- Full Text
- View/download PDF
55. Cost effectiveness and cost-utility analysis of a group-based diet intervention for treating major depression – the HELFIMED trial
- Author
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Segal, Leonie, primary, Twizeyemariya, Asterie, additional, Zarnowiecki, Dorota, additional, Niyonsenga, Theo, additional, Bogomolova, Svetlana, additional, Wilson, Amy, additional, O’Dea, Kerin, additional, and Parletta, Natalie, additional
- Published
- 2018
- Full Text
- View/download PDF
56. Composition and context drivers of residential property location value as a socioeconomic status measure
- Author
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Coffee, Neil T, primary, Lockwood, Tony, additional, Rossini, Peter, additional, Niyonsenga, Theo, additional, and McGreal, Stanley, additional
- Published
- 2018
- Full Text
- View/download PDF
57. Cost effectiveness and cost-utility analysis of a group-based diet intervention for treating major depression – the HELFIMED trial.
- Author
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Segal, Leonie, Twizeyemariya, Asterie, Zarnowiecki, Dorota, Niyonsenga, Theo, Bogomolova, Svetlana, Wilson, Amy, O'Dea, Kerin, and Parletta, Natalie
- Subjects
COST effectiveness ,MENTAL depression ,EXTERNALITIES ,EARLY death ,DIET ,PREMATURE menopause ,MEDITERRANEAN diet - Abstract
Background/objectives: Major depression has a negative impact on quality of life, increasing the risk of premature death. It imposes social and economic costs on individuals, families and society. Mental illness is now the leading cause globally of disability/lost quality life and premature mortality. Finding cost-effective treatments for depression is a public health priority. We report an economic evaluation of a dietary intervention for treating major depression. Methods: This economic evaluation drew on the HELFIMED RCT, a 3-month group-based Mediterranean-style diet (MedDiet) intervention (including cooking workshops), against a social group-program for people with major depression. We conducted (i) a cost-utility analysis, utility scores measured at baseline, 3-months and 6-months using the AQoL8D, modelled to 2 years (base case); (ii) a cost-effectiveness analysis, differential cost/case of depression resolved (to normal/mild) measured by the DASS. Differential program costs were calculated from resources use costed in AUD2017. QALYs were discounted at 3.5%pa. Results: Best estimate differential cost/QALY gain per person, MedDiet relative to social group was AUD2775. Probabilistic sensitivity analysis, varying costs, utility gain, model period found 95% likelihood cost/QALY less than AUD20,000. Estimated cost per additional case of depression resolved, MedDiet group relative to social group was AUD2,225. Conclusions: A MedDiet group-program for treating major depression was highly cost-effective relative to a social group-program, measured in terms of cost/QALY gain and cost per case of major depression resolved. Supporting access by persons with major depression to group-based dietary programs should be a policy priority. A change to funding will be needed to realise the potential benefits. [ABSTRACT FROM AUTHOR]
- Published
- 2020
- Full Text
- View/download PDF
58. Optimizing the measurement of comorbidity for a South Australian colorectal cancer population using administrative data.
- Author
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Pule, Lettie, Buckley, Elizabeth, Niyonsenga, Theo, and Roder, David
- Subjects
CALIBRATION ,COLON tumors ,EXPERIMENTAL design ,RESEARCH methodology ,RECTUM tumors ,REGRESSION analysis ,RISK assessment ,COMORBIDITY ,PREDICTIVE validity ,SEVERITY of illness index ,RECEIVER operating characteristic curves - Abstract
Rationale and objectives: In epidemiological research, it is essential to account for the confounding effects of factors such as age, stage, and comorbidity for accurate prediction of cancer outcomes. There are several internationally developed and commonly used comorbidity indices. However, none are regarded as the gold‐standard method. This study will assess and compare the predictive validity of established indices for use in a South Australian (SA) colorectal cancer (CRC) population against a local index. Furthermore, the prognostic influence of comorbidity on survival is investigated. Methods: A population‐based study of patients diagnosed with CRC from 2003 to 2012 and linked to in‐hospital data to retrieve comorbidity information was conducted. The predictive performance of established indices, Charlson comorbidity index (CCI), National Cancer Institute comorbidity index (NCI), Elixhauser comorbidity index (ECI), and C3 index was evaluated using the Fine and Gray competing risk regression and reported using measures of calibration and discrimination, area under the curve (AUC), and Brier score. Furthermore, to identify the optimal index, a local CRC comorbidity index (CRCCI) was also developed and its performance compared with the established indices. Results: Comorbidity models adjusted for age, sex, and stage showed that all indices were good predictors of mortality as measured by the AUC (CCI: 0.738, NCI: 0.742, ECI: 0.733, C3: 0.739). CRCCI had similar mortality prediction as established indices (CRCCI: 0.747). There was a significant increase in cumulative risk of noncancer and CRC‐specific mortality with increase in comorbidity scores. The two most prevalent comorbidities were hypertension and diabetes. Conclusions: The existing indices are still valid for adjusting for comorbidity and accurately predicting mortality in an SA CRC population. Internationally developed indices are preferred when policymakers and researchers wish to compare local study results with those of studies (national and international) that have used these indices. Comorbidity is a predictor of mortality and should be considered when assessing CRC survival. [ABSTRACT FROM AUTHOR]
- Published
- 2020
- Full Text
- View/download PDF
59. Comorbidities in Australian women with hormone‐dependent breast cancer: a population‐based analysis
- Author
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Ng, Huah Shin, primary, Koczwara, Bogda, additional, Roder, David M, additional, Niyonsenga, Theo, additional, and Vitry, Agnes I, additional
- Published
- 2018
- Full Text
- View/download PDF
60. Incidence of Comorbidities in Women with Breast Cancer Treated with Tamoxifen or an Aromatase Inhibitor: An Australian Population-Based Cohort Study
- Author
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Ng, Huah Shin, primary, Koczwara, Bogda, additional, Roder, David, additional, Niyonsenga, Theo, additional, and Vitry, Agnes, additional
- Published
- 2018
- Full Text
- View/download PDF
61. A Mediterranean-style dietary intervention supplemented with fish oil improves diet quality and mental health in people with depression: A randomized controlled trial (HELFIMED)
- Author
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Parletta, Natalie, primary, Zarnowiecki, Dorota, additional, Cho, Jihyun, additional, Wilson, Amy, additional, Bogomolova, Svetlana, additional, Villani, Anthony, additional, Itsiopoulos, Catherine, additional, Niyonsenga, Theo, additional, Blunden, Sarah, additional, Meyer, Barbara, additional, Segal, Leonie, additional, Baune, Bernhard T., additional, and O’Dea, Kerin, additional
- Published
- 2017
- Full Text
- View/download PDF
62. Does Physical Activity Mediate the Associations Between Local-Area Descriptive Norms, Built Environment Walkability, and Glycosylated Hemoglobin?
- Author
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Carroll, Suzanne J., primary, Niyonsenga, Theo, additional, Coffee, Neil T., additional, Taylor, Anne W., additional, and Daniel, Mark, additional
- Published
- 2017
- Full Text
- View/download PDF
63. Local descriptive body weight and dietary norms, food availability, and 10-year change in glycosylated haemoglobin in an Australian population-based biomedical cohort
- Author
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Carroll, Suzanne J., primary, Paquet, Catherine, additional, Howard, Natasha J., additional, Coffee, Neil T., additional, Adams, Robert J., additional, Taylor, Anne W., additional, Niyonsenga, Theo, additional, and Daniel, Mark, additional
- Published
- 2017
- Full Text
- View/download PDF
64. The impact of geographic unit of analysis on socioeconomic inequalities in cancer survival and distant summary stage – a population‐based study
- Author
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Tervonen, Hanna E., primary, Morrell, Stephen, additional, Aranda, Sanchia, additional, Roder, David, additional, You, Hui, additional, Niyonsenga, Theo, additional, Walton, Richard, additional, Baker, Deborah, additional, and Currow, David, additional
- Published
- 2016
- Full Text
- View/download PDF
65. Composition and context drivers of residential property location value as a socioeconomic status measure
- Author
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Coffee, Neil T, Lockwood, Tony, Rossini, Peter, Niyonsenga, Theo, and McGreal, Stanley
- Abstract
Research applying residential property value as a socioeconomic status measure is increasing. The literature includes several measures of residential property value socioeconomic status, all of which highlight location as an important component. This paper examines the drivers of the location component of residential property value that form the basis of its application as a socioeconomic status measure. The metropolitan area of Adelaide, South Australia, is used as a study area to analyse the composition and context embodied in residential property location value. The focus of this paper is to provide an understanding of the drivers of residential property value calculated as the relative location factor, deliberately constructed to reflect the effect on value due to location. The analysis reduced the traditional composition measures of social structure into a smaller number of factors using principal component analysis and regressed these against relative location factor. A spatial lens was applied to the results using Moran’s I to visualise the composition and context influence embodied in relative location factor. The results provided a significantly enhanced understanding of both the composition and context of socioeconomic status wealth that may be a more suitable socioeconomic status measure than the traditional composition measures of income, education and occupation. This paper provides an original interpretation of the contribution and use of residential property location value enabling a broader understanding of socioeconomic status, concluding that relative location factor provided a more informed measure of socioeconomic status, capable of enhancing social science and health research and policy formation.
- Published
- 2020
- Full Text
- View/download PDF
66. A Mediterranean-style dietary intervention supplemented with fish oil improves diet quality and mental health in people with depression: A randomized controlled trial (HELFIMED).
- Author
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Parletta, Natalie, Zarnowiecki, Dorota, Cho, Jihyun, Wilson, Amy, Bogomolova, Svetlana, Villani, Anthony, Itsiopoulos, Catherine, Niyonsenga, Theo, Blunden, Sarah, Meyer, Barbara, Segal, Leonie, Baune, Bernhard T., and O'Dea, Kerin
- Subjects
FISH oils ,NUTS ,RANDOMIZED controlled trials ,MENTAL health ,DIETARY supplements ,FATTY acid analysis ,DIET - Abstract
Objectives: We investigated whether a Mediterranean-style diet (MedDiet) supplemented with fish oil can improve mental health in adults suffering depression. Methods: Adults with self-reported depression were randomized to receive fortnightly food hampers and MedDiet cooking workshops for 3 months and fish oil supplements for 6 months, or attend social groups fortnightly for 3 months. Assessments at baseline, 3 and 6 months included mental health, quality of life (QoL) and dietary questionnaires, and blood samples for erythrocyte fatty acid analysis. Results:n = 152 eligible adults aged 18–65 were recruited (n = 95 completed 3-month and n = 85 completed 6-month assessments). At 3 months, the MedDiet group had a higher MedDiet score (t = 3.95, P < 0.01), consumed more vegetables (t = 3.95, P < 0.01), fruit (t = 2.10, P = 0.04), nuts (t = 2.29, P = 0.02), legumes (t = 2.41, P = 0.02) wholegrains (t = 2.63, P = 0.01), and vegetable diversity (t = 3.27, P < 0.01); less unhealthy snacks (t = −2.10, P = 0.04) and red meat/chicken (t = −2.13, P = 0.04). The MedDiet group had greater reduction in depression (t = −2.24, P = 0.03) and improved mental health QoL scores (t = 2.10, P = 0.04) at 3 months. Improved diet and mental health were sustained at 6 months. Reduced depression was correlated with an increased MedDiet score (r = −0.298, P = 0.01), nuts (r = −0.264, P = 0.01), and vegetable diversity (r = −0.303, P = 0.01). Other mental health improvements had similar correlations, most notably for increased vegetable diversity and legumes. There were some correlations between increased omega-3, decreased omega-6 and improved mental health. Discussion: This is one of the first randomized controlled trials to show that healthy dietary changes are achievable and, supplemented with fish oil, can improve mental health in people with depression. [ABSTRACT FROM AUTHOR]
- Published
- 2019
- Full Text
- View/download PDF
67. A 6-month randomised controlled trial investigating effects of Mediterranean-style diet and fish oil supplementation on dietary behaviour change, mental and cardiometabolic health and health-related quality of life in adults with depression (HELFIMED): study protocol
- Author
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Zarnowiecki, Dorota, primary, Cho, Jihyun, additional, Wilson, Amy, additional, Bogomolova, Svetlana, additional, Villani, Anthony, additional, Itsiopoulos, Catherine, additional, Niyonsenga, Theo, additional, O’Dea, Kerin, additional, Blunden, Sarah, additional, Meyer, Barbara, additional, Segal, Leonie, additional, and Parletta, Natalie, additional
- Published
- 2016
- Full Text
- View/download PDF
68. Fast-food exposure around schools in urban Adelaide
- Author
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Coffee, Neil T, primary, Kennedy, Hannah P, additional, and Niyonsenga, Theo, additional
- Published
- 2016
- Full Text
- View/download PDF
69. Incidence of comorbidities in women with breast cancer treated with tamoxifen or an aromatase inhibitor: an Australian population-based cohort study.
- Author
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Huah Shin Ng, Koczwara, Bogda, Roder, David, Niyonsenga, Theo, and Vitry, Agnes
- Subjects
TAMOXIFEN ,AROMATASE inhibitors ,BREAST tumors ,LONGITUDINAL method ,RESEARCH methodology ,RESEARCH funding ,TIME ,COMORBIDITY ,DISEASE incidence ,PROPORTIONAL hazards models ,RETROSPECTIVE studies ,THERAPEUTICS - Abstract
Background: The development of comorbidities has become increasingly relevant with longer-term cancer survival. Objective: To assess the pattern of comorbidities among Australian women with breast cancer treated with tamoxifen or an aromatase inhibitor. Design: Retrospective cohort study using Pharmaceutical Benefits Scheme (PBS) data (10% sample) from January 2003 to December 2014. Dispensing claims data were used to identify comorbidities and classified with the Rx-Risk-V model. The breast cancer cohort had tamoxifen or an aromatase inhibitor dispensed between 2004 and 2011 with no switching between types of endocrine therapy. Comparisons were made between the breast cancer cohort and specific control groups (age- and sex-matched at 1:10 ratio without any dispensing of anti-neoplastic agents during the study period) for the development of five individual comorbidities over time using Cox regression models. Results: Women treated with tamoxifen had a higher incidence of cardiovascular conditions, diabetes, and pain or pain-inflammation, but a lower incidence of hyperlipidaemia compared with non-cancer control groups, as indicated by PBS data. Women treated with aromatase inhibitors were more likely to develop cardiovascular conditions, osteoporosis, and pain or pain-inflammation compared with non-cancer control groups. The risks of hyperlipidaemia and osteoporosis were significantly lower among tamoxifen users compared with aromatase inhibitor users. Conclusion: Women with hormone-dependent breast cancer treated with an endocrine therapy had a higher risk of developing specified comorbid conditions than women without cancer, with different comorbidity profiles for those on tamoxifen versus aromatase inhibitors. Further research into the causes and mechanism of development and management of comorbidities after cancer is needed. [ABSTRACT FROM AUTHOR]
- Published
- 2018
- Full Text
- View/download PDF
70. Contributions of local-area fast-food availability and area-based weight and dietary norms to 10-year change in cardiometabolic risk
- Author
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Carroll, Suzanne J., primary, Paquet, Catherine, additional, Howard, Natasha J., additional, Coffee, Neil T., additional, Adams, Robert, additional, Taylor, Anne W., additional, Niyonsenga, Theo, additional, and Daniel, Mark, additional
- Published
- 2014
- Full Text
- View/download PDF
71. Change over time in wealth approximated by relative residential location factor is associated with changes over time in body mass index and waist circumference
- Author
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Coffee, Neil, primary, Howard, Natasha, additional, Paquet, Catherine, additional, Taylor, Anne, additional, Adams, Robert, additional, Hugo, Graeme, additional, Daniel, Mark, additional, and Niyonsenga, Theo, additional
- Published
- 2014
- Full Text
- View/download PDF
72. Racial/Ethnic Disparities in Failure to Initiate HIV Care: Role of HIV Testing Site, Individual Factors, and Neighborhood Factors, Florida, 2014–2015
- Author
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Trepka, Mary Jo, Sheehan, Diana M., Fennie, Kristopher P., Mauck, Daniel E., Lieb, Spencer, Maddox, Lorene M., and Niyonsenga, Theophile
- Published
- 2018
- Full Text
- View/download PDF
73. Local Retail Destinations and Middle-to-Older Adults’ Mobility Decline
- Author
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Takemi Sugiyama, Niyonsenga, Theo, Neil Coffee, and Daniel, Mark
74. 10-year assessment of predictive relationships between different dimensions of urban environments and incidents cardio-metabolic risk in South Australia
- Author
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Daniel, Mark, Niyonsenga, Theo, Neil Coffee, Howard, Natasha J., Catherine Paquet, and Taylor, Anne W.
75. A Mediterranean-style dietary intervention supplemented with fish oil improves diet quality and mental health in people with depression: A randomized controlled trial (HELFIMED)
- Author
-
Catherine Itsiopoulos, Natalie Parletta, Bernhard T. Baune, Kerin O'Dea, Barbara J. Meyer, Svetlana Bogomolova, Anthony Villani, Jihyun Cho, Dorota Zarnowiecki, Sarah Blunden, Amy L. Wilson, Theo Niyonsenga, Leonie Segal, Parletta, Natalie, Zarnowiecki, Dorota, Cho, Jihyun, Wilson, Amy, Bogomolova, Svetlana, Villani, Anthony, Itsiopoulos, Catherine, Niyonsenga, Theo, Blunden, Sarah, Meyer, Barbara, Segal, Leonie, Baune, Bernhard T, and O'Dea, Kerin
- Subjects
Male ,Mediterranean diet ,Medicine (miscellaneous) ,Diet, Mediterranean ,fish oil ,law.invention ,0302 clinical medicine ,Randomized controlled trial ,Quality of life ,law ,Medicine ,030212 general & internal medicine ,intervention ,Depression (differential diagnoses) ,Uncategorized ,2. Zero hunger ,Nutrition and Dietetics ,Depression ,General Neuroscience ,food and beverages ,General Medicine ,Middle Aged ,Fish oil ,3. Good health ,Mental Health ,Treatment Outcome ,Diet quality ,depression ,Female ,omega-3 ,mental health ,Adult ,Adolescent ,omega-6 ,03 medical and health sciences ,Young Adult ,Fish Oils ,Intervention (counseling) ,Environmental health ,Fatty Acids, Omega-6 ,Fatty Acids, Omega-3 ,Humans ,Aged ,business.industry ,Mental health ,quality of life ,Dietary Supplements ,Quality of Life ,business ,030217 neurology & neurosurgery - Abstract
Objectives: We investigated whether a Mediterranean-style diet (MedDiet) supplemented with fish oil can improve mental health in adults suffering depression. Methods: Adults with self-reported depression were randomized to receive fortnightly food hampers and MedDiet cooking workshops for 3 months and fish oil supplements for 6 months, or attend social groups fortnightly for 3 months. Assessments at baseline, 3 and 6 months included mental health, quality of life (QoL) and dietary questionnaires, and blood samples for erythrocyte fatty acid analysis. Results: n = 152 eligible adults aged 18–65 were recruited (n = 95 completed 3-month and n = 85 completed 6-month assessments). At 3 months, the MedDiet group had a higher MedDiet score (t = 3.95, P < 0.01), consumed more vegetables (t = 3.95, P < 0.01), fruit (t = 2.10, P = 0.04), nuts (t = 2.29, P = 0.02), legumes (t = 2.41, P = 0.02) wholegrains (t = 2.63, P = 0.01), and vegetable diversity (t = 3.27, P < 0.01); less unhealthy snacks (t = −2.10, P = 0.04) and red meat/chicken (t = −2.13, P = 0.04). The MedDiet group had greater reduction in depression (t = −2.24, P = 0.03) and improved mental health QoL scores (t = 2.10, P = 0.04) at 3 months. Improved diet and mental health were sustained at 6 months. Reduced depression was correlated with an increased MedDiet score (r = −0.298, P = 0.01), nuts (r = −0.264, P = 0.01), and vegetable diversity (r = −0.303, P = 0.01). Other mental health improvements had similar correlations, most notably for increased vegetable diversity and legumes. There were some correlations between increased omega-3, decreased omega-6 and improved mental health. Discussion: This is one of the first randomized controlled trials to show that healthy dietary changes are achievable and, supplemented with fish oil, can improve mental health in people with depression. Refereed/Peer-reviewed
- Published
- 2023
- Full Text
- View/download PDF
76. Young carer's and their mental health
- Author
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Theo Niyonsenga, Itismita Mohanty, Mohanty, Itismita, and Niyonsenga, Theo
- Subjects
Gerontology ,Health Policy ,Public Health, Environmental and Occupational Health ,Obstetrics and Gynecology ,young carers ,Mental health ,Weighting ,Psychiatry and Mental health ,primary care ,Infectious Diseases ,Inverse probability ,Pediatrics, Perinatology and Child Health ,Internal Medicine ,Observational study ,Geriatrics and Gerontology ,Public aspects of medicine ,RA1-1270 ,Psychology ,mental health - Abstract
Refereed/Peer-reviewed
- Published
- 2021
77. Cost effectiveness and cost-utility analysis of a group-based diet intervention for treating major depression-the HELFIMED trial
- Author
-
Leonie Segal, Kerin O'Dea, Natalie Parletta, Amy L. Wilson, Dorota Zarnowiecki, Asterie Twizeyemariya, Theo Niyonsenga, Svetlana Bogomolova, Segal, Leonie, Twizeyemariya, Asterie, Zarnowiecki, Dorota, Niyonsenga, Theo, Bogomolova, Svetlana, Wilson, Amy, O'Dea, Kerin, and Parletta, Natalie
- Subjects
0301 basic medicine ,economic evaluation ,Cost effectiveness ,Cost-Benefit Analysis ,Medicine (miscellaneous) ,Diet, Mediterranean ,law.invention ,03 medical and health sciences ,0302 clinical medicine ,Randomized controlled trial ,Quality of life ,law ,Economic cost ,Mediterranean diet ,Humans ,Medicine ,Depression (differential diagnoses) ,health care economics and organizations ,Depressive Disorder, Major ,Cost–utility analysis ,diet intervention ,030109 nutrition & dietetics ,Nutrition and Dietetics ,DASS ,cost effectiveness ,business.industry ,General Neuroscience ,cost-utility analysis ,General Medicine ,Treatment Outcome ,Economic evaluation ,depression ,Quality of Life ,business ,030217 neurology & neurosurgery ,Diet Therapy ,Demography - Abstract
Background/objectives: Major depression has a negative impact on quality of life, increasing the risk of premature death. It imposes social and economic costs on individuals, families and society. Mental illness is now the leading cause globally of disability/lost quality life and premature mortality. Finding cost-effective treatments for depression is a public health priority. We report an economic evaluation of a dietary intervention for treating major depression. Methods: This economic evaluation drew on the HELFIMED RCT, a 3-month group-based Mediterranean-style diet (MedDiet) intervention (including cooking workshops), against a social group-program for people with major depression. We conducted (i) a cost-utility analysis, utility scores measured at baseline, 3-months and 6-months using the AQoL8D, modelled to 2 years (base case); (ii) a cost-effectiveness analysis, differential cost/case of depression resolved (to normal/mild) measured by the DASS. Differential program costs were calculated from resources use costed in AUD2017. QALYs were discounted at 3.5%pa. Results: Best estimate differential cost/QALY gain per person, MedDiet relative to social group was AUD2775. Probabilistic sensitivity analysis, varying costs, utility gain, model period found 95% likelihood cost/QALY less than AUD20,000. Estimated cost per additional case of depression resolved, MedDiet group relative to social group was AUD2,225. Conclusions: A MedDiet group-program for treating major depression was highly cost-effective relative to a social group-program, measured in terms of cost/QALY gain and cost per case of major depression resolved. Supporting access by persons with major depression to group-based dietary programs should be a policy priority. A change to funding will be needed to realise the potential benefits. Refereed/Peer-reviewed
- Published
- 2020
78. Composition and context drivers of residential property location value as a socioeconomic status measure
- Author
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Peter Rossini, Stanley McGreal, Tony Lockwood, Theo Niyonsenga, Neil T. Coffee, Coffee, Neil, Lockwood, Tony, Rossini, Peter, Niyonsenga, Theo, and McGreal, Stanley
- Subjects
Measure (data warehouse) ,composition and context ,spatial analysis ,principal component analysis ,Geography, Planning and Development ,Residential property ,0211 other engineering and technologies ,021107 urban & regional planning ,Context (language use) ,02 engineering and technology ,Management, Monitoring, Policy and Law ,Urban Studies ,socioeconomic status ,03 medical and health sciences ,0302 clinical medicine ,Geography ,relative location factor ,Architecture ,030212 general & internal medicine ,Socioeconomics ,Value (mathematics) ,Socioeconomic status ,Nature and Landscape Conservation - Abstract
Research applying residential property value as a socioeconomic status measure is increasing. The literature includes several measures of residential property value socioeconomic status, all of which highlight location as an important component. This paper examines the drivers of the location component of residential property value that form the basis of its application as a socioeconomic status measure. The metropolitan area of Adelaide, South Australia, is used as a study area to analyse the composition and context embodied in residential property location value. The focus of this paper is to provide an understanding of the drivers of residential property value calculated as the relative location factor, deliberately constructed to reflect the effect on value due to location. The analysis reduced the traditional composition measures of social structure into a smaller number of factors using principal component analysis and regressed these against relative location factor. A spatial lens was applied to the results using Moran’s I to visualise the composition and context influence embodied in relative location factor. The results provided a significantly enhanced understanding of both the composition and context of socioeconomic status wealth that may be a more suitable socioeconomic status measure than the traditional composition measures of income, education and occupation. This paper provides an original interpretation of the contribution and use of residential property location value enabling a broader understanding of socioeconomic status, concluding that relative location factor provided a more informed measure of socioeconomic status, capable of enhancing social science and health research and policy formation. Refereed/Peer-reviewed
- Published
- 2020
79. The use of travel time to measure geographic accessibility to breast screening services in New South Wales, Australia short paper
- Author
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David Roder, Mark Daniel, Deborah van Gaans, Catherine Miles, Theo Niyonsenga, Daniel J Weiss, Neil T. Coffee, Matthew Warner-Smith, van Gaans, Deborah, Coffee, Neil, Niyonsenga, Theo, Miles, Catherine, Warner-Smith, Matthew, Daniel, Mark, Roder, David, and Weiss, Daniel
- Subjects
Service (business) ,education.field_of_study ,Measure (data warehouse) ,Traverse ,Project commissioning ,Computer science ,Geography, Planning and Development ,Population ,medicine.disease ,accessibility ,health serviced ,Transport engineering ,equity ,Breast cancer ,breast screen ,mommography ,restrict ,medicine ,General Earth and Planetary Sciences ,Breast screening ,time travel ,education - Abstract
In 2018, the World Health Organization set a goal to increase the proportion of breast cancers identified at an early stage. Early detection allows for more effective treatment and a reduction in the risk of death from breast cancer. Poor access may restrict participation in screening, diagnostic and treatment services, with flow-on effects on stage at diagnosis and survival. This paper presents spatial analysis of travel time to breast screening services in New South Wales, Australia to measure the geographic accessibility of services to the population they serve. The travel time surface was created using a friction surface that estimates the time required to traverse each pixel within a global grid, and a least cost path algorithm to find the optimised route from each output pixel to the breast screen services. The friction surface was derived using a set of input layers, with the roads layer being the most critical for defining travel times. The generated surface of travel time to breast screen services in New South Wales has shown that over 90% of the population are within 20 min' drive time of either a fixed or mobile breast screen service and that 100% of the population are within 100 min' drive time of a breast screen service. The ability to identify and measure spatial variations in geographic accessibility via travel time is vital to plan breast screening services and reduce inequalities in health outcomes. Refereed/Peer-reviewed
- Published
- 2020
80. A Longitudinal Analysis of Mental and General Health Status of Informal Carers in Australia
- Author
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Theo Niyonsenga, Itismita Mohanty, Mohanty, Itismita, and Niyonsenga, Theo
- Subjects
Adult ,Male ,Gerontology ,medicine.medical_specialty ,Adolescent ,Health Status ,health care facilities, manpower, and services ,health behaviour and informal carers age ,General health ,Young Adult ,03 medical and health sciences ,0302 clinical medicine ,Quality of life (healthcare) ,Surveys and Questionnaires ,Epidemiology ,Informal carers health ,Humans ,Medicine ,Longitudinal Studies ,030212 general & internal medicine ,Socioeconomic status ,health care economics and organizations ,Aged ,Retrospective Studies ,Aged, 80 and over ,informal carers health ,business.industry ,lcsh:Public aspects of medicine ,Health behaviour and informal carers age ,030503 health policy & services ,Public health ,Australia ,Public Health, Environmental and Occupational Health ,lcsh:RA1-1270 ,social sciences ,Middle Aged ,Mental health ,humanities ,general health ,Mental Health ,Caregivers ,Drinking Status ,Workforce ,Female ,Biostatistics ,0305 other medical science ,business ,mental health ,Research Article - Abstract
Background The study investigated the self-assessed mental and general health status of informal carers in Australia. It evaluated the influence of carer’s health behaviours, namely physical activity, smoking and drinking status, along with their social connectedness and workforce engagement on their health status. Methods The study used a retrospective longitudinal design using data from the Household Income and Labour Dynamics of Australia survey, waves 5–15 (2005–2015). It included individuals aged 15 years and older from Australian households surveyed over a period of 11 years. The sample consisted of 23,251 individuals. The outcome measures included: mental health, general health and physical functioning domains of the Short Form 36 Questionnaire, a widely used multi-dimensional measure of health-related quality of life. Using fixed effects regression and following individuals over time, the analysis took care of the issue of individuals self-selecting themselves as carers due to some predisposing factors such as age, poor health, socioeconomic status and sedentary behaviour. Results There were statistically significant carer-noncarer status differences in mental (Beta = − 0.587, p = 0.003) and general health (Beta = − 0.670, p = 0.001) outcomes. Aging had a modifying impact on carers’ mental and general health outcomes. Older carers coped better with their caregiving responsibilities than younger ones. Moreover, while physical activities had a positive influence on both mental and general health for non-carers, with more activities generating better health outcomes, it only had a modifying impact on carers’ mental health. Furthermore, the study found that moderate levels of social drinking had beneficial modifying impact on carers’ mental and general health. Conclusion This study added value to the literature on informal carers’ mental and general health in Australia by identifying some of the protective and risk factors. The study found the modifying effects of carers’ age, health behaviours such as physical activity, smoking and drinking status on their health. Finally, the study identified an apparent beneficial link between moderate levels of social drinking and carer health that needs to be further explored with more targeted future research.
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- 2019
81. Incidence of Comorbidities in Women with Breast Cancer Treated with Tamoxifen or an Aromatase Inhibitor: An Australian Population-Based Cohort Study
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David Roder, Theo Niyonsenga, Agnes Vitry, Huah Shin Ng, Bogda Koczwara, Ng, Huah Shin, Koczwara, Bogda, Roder, David, Niyonsenga, Theo, and Vitry, Agnes
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Oncology ,medicine.medical_specialty ,medicine.drug_class ,lcsh:Medicine ,comorbidities ,03 medical and health sciences ,0302 clinical medicine ,Breast cancer ,Internal medicine ,Epidemiology of cancer ,Epidemiology ,medicine ,030212 general & internal medicine ,hormone-dependent breast cancer ,Aromatase inhibitor ,tamoxifen ,endocrine therapy ,business.industry ,Incidence (epidemiology) ,lcsh:R ,Cancer ,medicine.disease ,030220 oncology & carcinogenesis ,aromatase inhibitor ,Original Article ,business ,Tamoxifen ,cancer epidemiology ,Cohort study ,medicine.drug - Abstract
Background The development of comorbidities has become increasingly relevant with longer-term cancer survival. Objective To assess the pattern of comorbidities among Australian women with breast cancer treated with tamoxifen or an aromatase inhibitor. Design Retrospective cohort study using Pharmaceutical Benefits Scheme (PBS) data (10% sample) from January 2003 to December 2014. Dispensing claims data were used to identify comorbidities and classified with the Rx-Risk-V model. The breast cancer cohort had tamoxifen or an aromatase inhibitor dispensed between 2004 and 2011 with no switching between types of endocrine therapy. Comparisons were made between the breast cancer cohort and specific control groups (age- and sex-matched at 1:10 ratio without any dispensing of anti-neoplastic agents during the study period) for the development of five individual comorbidities over time using Cox regression models. Results Women treated with tamoxifen had a higher incidence of cardiovascular conditions, diabetes, and pain or pain-inflammation, but a lower incidence of hyperlipidaemia compared with non-cancer control groups, as indicated by PBS data. Women treated with aromatase inhibitors were more likely to develop cardiovascular conditions, osteoporosis, and pain or pain-inflammation compared with non-cancer control groups. The risks of hyperlipidaemia and osteoporosis were significantly lower among tamoxifen users compared with aromatase inhibitor users. Conclusions Women with hormone-dependent breast cancer treated with an endocrine therapy had a higher risk of developing specified comorbid conditions than women without cancer, with different comorbidity profiles for those on tamoxifen versus aromatase inhibitors. Further research into the causes and mechanism of development and management of comorbidities after cancer is needed.
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- 2018
82. Comorbidities in Australian women with hormone‐dependent breast cancer: a population‐based analysis
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Huah Shin Ng, Theo Niyonsenga, David Roder, Bogda Koczwara, Agnes Vitry, Ng, Huah Shin, Koczwara, Bogda, Roder, David M, Niyonsenga, Theo, and Vitry, Agnes I
- Subjects
medicine.medical_specialty ,Antineoplastic Agents, Hormonal ,Osteoporosis ,Breast Neoplasms ,Comorbidity ,Cohort Studies ,03 medical and health sciences ,0302 clinical medicine ,Breast cancer ,Diabetes mellitus ,Internal medicine ,medicine ,Humans ,030212 general & internal medicine ,hormone-dependent breast cancer ,Depression (differential diagnoses) ,Aged ,Retrospective Studies ,Aged, 80 and over ,endocrine therapy ,Depression ,business.industry ,Hazard ratio ,Australia ,Cancer ,General Medicine ,Middle Aged ,medicine.disease ,Cardiovascular Diseases ,030220 oncology & carcinogenesis ,Chronic Disease ,Female ,business ,Cohort study - Abstract
Objective: To compare how frequently selected chronic diseases developed in women with breast cancer receiving endocrine therapy, and in women without cancer. Design, setting and participants: Retrospective, rolling cohort study, analysing a random 10% sample of Pharmaceutical Benefits Scheme (PBS) data for the period 1 January 2003 – 31 December 2014. Women with breast cancer who first commenced endocrine therapy between January 2004 and December 2011 were identified, and age- and sex-matched (1:10) by comorbidity with control groups of women who did not have a dispensing record for antineoplastic agents during the study period or the comorbidity of interest at baseline. Main outcome measures: Development of any of eight pre-selected comorbidities, identified in PBS claims data with the RxRisk-V model. Results: Women with hormone-dependent breast cancer were significantly more likely than women in the control group to develop depression (overall hazard ratio [HR], 1.36; 95% CI, 1.26–1.46), pain or pain–inflammation (HR, 1.30; 95% CI, 1.23–1.38), osteoporosis (overall HR, 1.27; 95% CI, 1.17–1.39), diabetes (HR, 1.24; 95% CI, 1.10–1.41), cardiovascular disorders (overall HR, 1.22; 95% CI, 1.13–1.32), and gastric acid disorders (HR, 1.20; 95% CI, 1.13–1.28). The hazard ratios for developing cardiovascular disorders, depression and osteoporosis were highest during the first year of endocrine therapy. The risk of hyperlipidaemia was lower among women with breast cancer than in the control group (HR, 0.88; 95% CI, 0.81–0.96). There was no significant difference between the two groups in the risk of reactive airway diseases (HR, 1.05; 95% CI, 0.98–1.13). Conclusion: Comorbid conditions are more likely to develop in women who have been diagnosed with hormone-dependent breast cancer than in women without cancer. Our results further support the need to develop appropriate models of care to manage the multiple chronic disorders of breast cancer survivors. Refereed/Peer-reviewed
- Published
- 2018
83. The impact of geographic unit of analysis on socioeconomic inequalities in cancer survival and distant summary stage – a population‐based study
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David Roder, David C. Currow, Theo Niyonsenga, Stephen Morrell, Hanna E. Tervonen, Deborah Baker, Hui You, Sanchia Aranda, Richard Walton, Tervonen, Hanna E, Morrell, Stephen, Aranda, Sanchia, Roder, David, You, Hui, Niyonsenga, Theo, Walton, Richard, Baker, Deborah, and Currow, David
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Gerontology ,Male ,Lung Neoplasms ,neoplasms ,Logistic regression ,survival analysis ,Cohort Studies ,0302 clinical medicine ,Residence Characteristics ,Neoplasms ,Medicine ,030212 general & internal medicine ,Registries ,education.field_of_study ,lcsh:Public aspects of medicine ,Middle Aged ,030220 oncology & carcinogenesis ,Population Surveillance ,Female ,Public Health ,New South Wales ,Colorectal Neoplasms ,Cohort study ,Population ,Breast Neoplasms ,socioeconomic factors ,03 medical and health sciences ,Breast cancer ,Humans ,education ,Socioeconomic status ,Survival analysis ,Disadvantage ,Neoplasm Staging ,Aged ,business.industry ,Public Health, Environmental and Occupational Health ,Australia ,Prostatic Neoplasms ,lcsh:RA1-1270 ,Health Status Disparities ,staging ,medicine.disease ,Survival Analysis ,Cancer registry ,Social Class ,Socioeconomic Factors ,business ,Demography - Abstract
© 2016 Public Health Association of Australia Objective: When using area-level disadvantage measures, size of geographic unit can have major effects on recorded socioeconomic cancer disparities. This study examined the extent of changes in recorded socioeconomic inequalities in cancer survival and distant stage when the measure of socioeconomic disadvantage was based on smaller Census Collection Districts (CDs) instead of Statistical Local Areas (SLAs). Methods: Population-based New South Wales Cancer Registry data were used to identify cases diagnosed with primary invasive cancer in 2000–2008 (n=264,236). Logistic regression and competing risk regression modelling were performed to examine socioeconomic differences in odds of distant stage and hazard of cancer death for all sites combined and separately for breast, prostate, colorectal and lung cancers. Results: For all sites collectively, associations between socioeconomic disadvantage and cancer survival and distant stage were stronger when the CD-based socioeconomic disadvantage measure was used compared with the SLA-based measure. The CD-based measure showed a more consistent socioeconomic gradient with a linear upward trend of risk of cancer death/distant stage with increasing socioeconomic disadvantage. Site-specific analyses provided similar findings for the risk of death but less consistent results for the likelihood of distant stage. Conclusions: The use of socioeconomic disadvantage measure based on the smallest available spatial unit should be encouraged in the future. Implications for public health: Disadvantage measures based on small spatial units can more accurately identify socioeconomic cancer disparities to inform priority settings in service planning.
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- 2017
84. Optimizing the measurement of comorbidity for a South Australian colorectal cancer population using administrative data
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Elizabeth Buckley, Lettie Pule, David Roder, Theo Niyonsenga, Pule, Lettie, Buckley, Elizabeth, Niyonsenga, Theo, and Roder, David
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Predictive validity ,medicine.medical_specialty ,Index (economics) ,Population ,colorectal cancer ,Comorbidity ,survival ,03 medical and health sciences ,Epidemiology ,South Australia ,Medicine ,Humans ,education ,education.field_of_study ,business.industry ,030503 health policy & services ,Health Policy ,Confounding ,Public Health, Environmental and Occupational Health ,Australia ,prediction models ,medicine.disease ,Prognosis ,comorbidity ,Brier score ,0305 other medical science ,business ,Colorectal Neoplasms ,Predictive modelling ,Demography - Abstract
Rationale and objectives: In epidemiological research, it is essential to account for the confounding effects of factors such as age, stage, and comorbidity for accurate prediction of cancer outcomes. There are several internationally developed and commonly used comorbidity indices. However, none are regarded as the gold-standard method. This study will assess and compare the predictive validity of established indices for use in a South Australian (SA) colorectal cancer (CRC) population against a local index. Furthermore, the prognostic influence of comorbidity on survival is investigated. Methods: A population-based study of patients diagnosed with CRC from 2003 to 2012 and linked to in-hospital data to retrieve comorbidity information was conducted. The predictive performance of established indices, Charlson comorbidity index (CCI), National Cancer Institute comorbidity index (NCI), Elixhauser comorbidity index (ECI), and C3 index was evaluated using the Fine and Gray competing risk regression and reported using measures of calibration and discrimination, area under the curve (AUC), and Brier score. Furthermore, to identify the optimal index, a local CRC comorbidity index (CRCCI) was also developed and its performance compared with the established indices. Results: Comorbidity models adjusted for age, sex, and stage showed that all indices were good predictors of mortality as measured by the AUC (CCI: 0.738, NCI: 0.742, ECI: 0.733, C3: 0.739). CRCCI had similar mortality prediction as established indices (CRCCI: 0.747). There was a significant increase in cumulative risk of noncancer and CRC-specific mortality with increase in comorbidity scores. The two most prevalent comorbidities were hypertension and diabetes. Conclusions: The existing indices are still valid for adjusting for comorbidity and accurately predicting mortality in an SA CRC population. Internationally developed indices are preferred when policymakers and researchers wish to compare local study results with those of studies (national and international) that have used these indices. Comorbidity is a predictor of mortality and should be considered when assessing CRC survival Refereed/Peer-reviewed
- Published
- 2019
85. Associations between local descriptive norms for overweight/obesity and insufficient fruit intake, individual-level diet, and 10-year change in body mass index and glycosylated haemoglobin in an Australian cohort
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Suzanne J. Carroll, Neil T. Coffee, Mark Daniel, Theo Niyonsenga, Anne W. Taylor, Carroll, Suzanne J, Niyonsenga, Theo, Coffee, Neil T, Taylor, Anne W, and Daniel, Mark
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Male ,Health Behavior ,Medicine (miscellaneous) ,Overweight ,Social Environment ,Body Mass Index ,Cohort Studies ,0302 clinical medicine ,Residence Characteristics ,cardiometabolic risk ,South Australia ,Vegetables ,Prevalence ,Social Norms ,Medicine ,030212 general & internal medicine ,lcsh:RC620-627 ,2. Zero hunger ,education.field_of_study ,Nutrition and Dietetics ,lcsh:Public aspects of medicine ,Middle Aged ,16. Peace & justice ,overweight and obesity ,lcsh:Nutritional diseases. Deficiency diseases ,Cohort ,Income ,Female ,medicine.symptom ,Cohort study ,Adult ,Overweight and obesity ,Population ,030209 endocrinology & metabolism ,Physical Therapy, Sports Therapy and Rehabilitation ,Dietary behaviour ,Population health ,Clinical nutrition ,Descriptive norms ,03 medical and health sciences ,Environmental health ,dietary behaviour ,Humans ,Obesity ,education ,Life Style ,Aged ,Glycated Hemoglobin ,business.industry ,Research ,nutritional and metabolic diseases ,lcsh:RA1-1270 ,Feeding Behavior ,medicine.disease ,Cardiometabolic risk ,Diet ,Fruit ,business ,descriptive norms ,Body mass index - Abstract
Background: Descriptive norms (what other people do) relate to individual-level dietary behaviour and health outcome including overweight and obesity. Descriptive norms vary across residential areas but the impact of spatial variation in norms on individual-level diet and health is poorly understood. This study assessed spatial associations between local descriptive norms for overweight/obesity and insufficient fruit intake (spatially-specific local prevalence), and individual-level dietary intakes (fruit, vegetable and sugary drinks) and 10-year change in body mass index (BMI) and glycosylated haemoglobin (HbA1c). Methods: HbA1c and BMI were clinically measured three times over 10 years for a population-based adult cohort (n = 4056) in Adelaide, South Australia. Local descriptive norms for both overweight/obesity and insufficient fruit intake specific to each cohort participant were calculated as the prevalence of these factors, constructed from geocoded population surveillance data aggregated for 1600 m road-network buffers centred on cohort participants' residential addresses. Latent growth models estimated the effect of local descriptive norms on dietary behaviours and change in HbA1c and BMI, accounting for spatial clustering and covariates (individual-level age, sex, smoking status, employment and education, and area-level median household income). Results: Local descriptive overweight/obesity norms were associated with individual-level fruit intake (inversely) and sugary drink consumption (positively), and worsening HbA1c and BMI. Spatially-specific local norms for insufficient fruit intake were associated with individual-level fruit intake (inversely) and sugary drink consumption (positively) and worsening HbA1c but not change in BMI. Individual-level fruit and vegetable intakes were not associated with change in HbA1c or BMI. Sugary drink consumption was also not associated with change in HbA1c but rather with increasing BMI. Conclusion: Adverse local descriptive norms for overweight/obesity and insufficient fruit intake are associated with unhealthful dietary intakes and worsening HbA1c and BMI. As such, spatial variation in lifestyle-related norms is an important consideration relevant to the design of population health interventions. Adverse local norms influence health behaviours and outcomes and stand to inhibit the effectiveness of traditional intervention efforts not spatially tailored to local population characteristics. Spatially targeted social de-normalisation strategies for regions with high levels of unhealthful norms may hold promise in concert with individual, environmental and policy intervention approaches. Refereed/Peer-reviewed
- Published
- 2018
86. Does where you live influence your socio-economic status?
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Peter Rossini, Tony Lockwood, Stanley McGreal, Neil T. Coffee, Theo Niyonsenga, Lockwood, Tony, Coffee, Neil T, Rossini, Peter, Niyonsenga, Theo, and McGreal, Stanley
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Property (philosophy) ,spatial analysis ,media_common.quotation_subject ,socio-economic status ,Geography, Planning and Development ,Context (language use) ,Management, Monitoring, Policy and Law ,Unit (housing) ,03 medical and health sciences ,0302 clinical medicine ,Econometrics ,residential property ,030212 general & internal medicine ,Proxy (statistics) ,Socioeconomic status ,Nature and Landscape Conservation ,media_common ,030505 public health ,Variables ,societal wellbeing ,Forestry ,GIS ,Geography ,Hedonic regression ,0305 other medical science ,SES ,Database transaction - Abstract
The relationship between the wellbeing of society and understanding of land market structure and behaviour is an important research theme for understanding socioeconomic status (SES). Traditional SES area based measures of income, occupation and education are generally applied in the examination of a broad spectrum of societal issues. This paper examines the contribution of understanding the spatial variation of SES based upon residential property sales data unrestricted by the traditional artificial geographic boundaries in which SES is assumed uniform. Originality lies in identifying the locational component of residential property wealth as a proxy for SES. It includes market behavioural characteristics that reflect both the context and composition at particular locations. This provides a broader understanding of SES than income, occupation and education. The analysis uses a hedonic regression model based on transactions of detached housing. The model is specified using only available property attributes as independent variables and is therefore blind to location. The residuals from this hedonic model are used to calculate the relative location factor (RLF) for each transaction property. These were interpolated as a continuous surface capable of predicting values at the individual property level or aggregated to a spatial unit relevant to the particular application. There was a significant correlation with the traditional SES indicators and health outcomes that have traditionally been shown to have a correlation with SES. Refereed/Peer-reviewed
- Published
- 2018
87. Does physical activity mediate the associations between local-area descriptive norms, built environment walkability, and glycosylated hemoglobin?
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Anne W. Taylor, Neil T. Coffee, Mark Daniel, Theo Niyonsenga, Suzanne J. Carroll, Carroll, Suzanne J, Niyonsenga, Theo, Coffee, Neil T, Taylor, Anne W, and Daniel, Mark
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Male ,Health Status ,Health, Toxicology and Mutagenesis ,Health Behavior ,Poison control ,lcsh:Medicine ,physical activity ,Walking ,Overweight ,Cohort Studies ,0302 clinical medicine ,Residence Characteristics ,Risk Factors ,Prevalence ,030212 general & internal medicine ,Built environment ,education.field_of_study ,cardiometabolic disease ,residential environments ,descriptive norms ,built environment ,walkability ,mediation ,glycosylated hemoglobin ,Middle Aged ,3. Good health ,Walkability ,Income ,Marital status ,Female ,medicine.symptom ,Adult ,Mediation (statistics) ,Population ,030209 endocrinology & metabolism ,Motor Activity ,Article ,03 medical and health sciences ,Environmental health ,medicine ,Humans ,Obesity ,education ,Glycated Hemoglobin ,lcsh:R ,Public Health, Environmental and Occupational Health ,Environment Design ,Self Report ,Body mass index - Abstract
Associations between local-area residential features and glycosylated hemoglobin (HbA 1c ) may be mediated by individual-level health behaviors. Such indirect effects have rarely been tested. This study assessed whether individual-level self-reported physical activity mediated the influence of local-area descriptive norms and objectively expressed walkability on 10-year change in HbA 1c . HbA 1c was assessed three times for adults in a 10-year population-based biomedical cohort (n = 4056). Local-area norms specific to each participant were calculated, aggregating responses from a separate statewide surveillance survey for 1600 m road-network buffers centered on participant addresses (local prevalence of overweight/obesity (body mass index ≥25 kg/m 2 ) and physical inactivity ( < 150 min/week)). Separate latent growth models estimated direct and indirect (through physical activity) effects of local-area exposures on change in HbA 1c , accounting for spatial clustering and covariates (individual-level age, sex, smoking status, marital status, employment and education, and area-level median household income). HbA 1c worsened over time. Local-area norms directly and indirectly predicted worsening HbA 1c trajectories. Walkability was directly and indirectly protective of worsening HbA 1c . Local-area descriptive norms and walkability influence cardiometabolic risk trajectory through individual-level physical activity. Efforts to reduce population cardiometabolic risk should consider the extent of local-area unhealthful behavioral norms and walkability in tailoring strategies to improve physical activity. Refereed/Peer-reviewed
- Published
- 2017
88. A 6-month randomised controlled trial investigating effects of Mediterranean-style diet and fish oil supplementation on dietary behaviour change, mental and cardiometabolic health and health-related quality of life in adults with depression (HELFIMED): study protocol
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Natalie Parletta, Kerin O'Dea, Catherine Itsiopoulos, Theo Niyonsenga, Barbara J. Meyer, Dorota Zarnowiecki, Anthony Villani, Jihyun Cho, Leonie Segal, Amy L. Wilson, Sarah Blunden, Svetlana Bogomolova, Zarnowiecki, Dorota, Cho, Jihyun, Wilson, Amy, Bogomolova, Svetlana, Villani, Anthony, Itsiopoulos, Catherine, Niyonsenga,Theo, O'Dea, Kerin, Blunden, Sarah, Meyer, Barbara, Segal, Leonie, and Parletta, Natalie
- Subjects
0301 basic medicine ,medicine.medical_specialty ,Mediterranean diet ,Endocrinology, Diabetes and Metabolism ,Nutrition Education ,Medicine (miscellaneous) ,law.invention ,03 medical and health sciences ,0302 clinical medicine ,Quality of life (healthcare) ,Randomized controlled trial ,law ,Environmental health ,medicine ,030212 general & internal medicine ,Depression (differential diagnoses) ,2. Zero hunger ,030109 nutrition & dietetics ,Nutrition and Dietetics ,DASS ,business.industry ,Public health ,Public Health, Environmental and Occupational Health ,Mental health ,3. Good health ,quality of life ,depression ,Physical therapy ,business ,cardiometabolic health ,study protocol ,Study protocol ,Cardiometabolic health ,Depression ,Quality of life - Abstract
Background: Modern diets, characterised by excess consumption of processed foods, are accompanied by an epidemic of chronic diseases. Cardiovascular disease and depression carry a large burden of disease and often occur together. Poor dietary patterns have been identified as an independent risk factor for depression while healthy diets with minimally processed food are protective. Traditional Mediterranean diets have been shown to reduce risk of cardiovascular disease; however there is a need for clinical trials in people with depression. This paper reports the study protocol of a Mediterranean-style diet intervention conducted in adults with self-reported depression. Methods/design: HELFIMED is a parallel 6-month randomised controlled trial investigating whether dietary patterns can be improved in people with depressive symptoms and whether healthier diet combined with fish oil supplementation can improve mental and cardiometabolic health and quality of life. Adults aged 18-65 years with self-reported depressive symptoms over the previous two months (N = 163) were block-randomised on age and gender between May 2014 and June 2015 to receive nutrition education, food hampers, fortnightly cooking workshops based on Mediterranean-style dietary principles for 3 months and fish oil supplementation for 6 months, or to attend fortnightly social groups (control group) for 3 months. All participants completed mental health (DASS and PANAS), quality of life, dietary and shopping and budgeting questionnaires and provided anthropometric measurements, blood and urine samples at baseline, 3 and 6 months. Additionally the treatment group attended focus groups at 3 and 6 months. Primary and secondary outcomes will be analysed using linear mixed modelling and correlations will investigate associations between improved health outcomes and subjective/objective measures of improved diet/nutritional status. Discussion: This study will contribute causal evidence to prior observational and longitudinal studies that have shown associations between Mediterranean diet and mental health. The results will inform public health and clinical strategies for treatment of depression and comorbid cardiometabolic risk factors.Trial registration: Australian New Zealand Clinical Trials Register (ACTRN12614000438651). Trial registration date: 23rd April 2014. Refereed/Peer-reviewed
- Published
- 2016
89. Fast-food exposure around schools in urban Adelaide
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Hannah P Kennedy, Neil T. Coffee, Theo Niyonsenga, Coffee, Neil T, Kennedy, Hannah P, and Niyonsenga, Theo
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Index (economics) ,socio-economic status ,Medicine (miscellaneous) ,schools ,Social class ,Logistic regression ,03 medical and health sciences ,symbols.namesake ,0302 clinical medicine ,Residence Characteristics ,Environmental health ,South Australia ,geographic information system ,030212 general & internal medicine ,Poisson regression ,fast-food exposure ,Socioeconomic status ,030505 public health ,Nutrition and Dietetics ,Schools ,Public Health, Environmental and Occupational Health ,Land cost ,Metropolitan area ,Research Papers ,Disadvantaged ,Geography ,Social Class ,symbols ,Fast Foods ,0305 other medical science - Abstract
ObjectiveTo assess whether exposure to fast-food outlets around schools differed depending on socio-economic status (SES).DesignBinary logistic regression was used to investigate the presence and zero-inflated Poisson regression was used for the count (due to the excess of zeroes) of fast food within 1000 m and 15000 m road network buffers around schools. The low and middle SES tertiles were combined due to a lack of significant variation as the ‘disadvantaged’ group and compared with the high SES tertile as the ‘advantaged’ group. School SES was expressed using the 2011 Australian Bureau of Statistics, socio-economic indices for areas, index of relative socio-economic disadvantage. Fast-food data included independent takeaway food outlets and major fast-food chains.SettingMetropolitan Adelaide, South Australia.SubjectsA total of 459 schools were geocoded to the street address and 1000 m and 1500 m road network distance buffers calculated.ResultsThere was a 1·6 times greater risk of exposure to fast food within 1000 m (OR=1·634; 95 % 1·017, 2·625) and a 9·5 times greater risk of exposure to a fast food within 1500 m (OR=9·524; 95 % CI 3·497, 25·641) around disadvantaged schools compared with advantaged schools.ConclusionsDisadvantaged schools were exposed to more fast food, with more than twice the number of disadvantaged schools exposed to fast food. The higher exposure to fast food near more disadvantaged schools may reflect lower commercial land cost in low-SES areas, potentially creating more financially desirable investments for fast-food developers.
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- 2016
90. Local descriptive norms for overweight/obesity and physical inactivity, features of the built environment, and 10-year change in glycosylated haemoglobin in an Australian population-based biomedical cohort
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Neil T. Coffee, Anne W. Taylor, Theo Niyonsenga, Catherine Paquet, Suzanne J. Carroll, Natasha J. Howard, Mark Daniel, Carroll, Suzanne J, Paquet, Catherine, Howard, Natasha Jayne, Coffee, Neil T, Taylor, Anne W, Niyonsenga, Theo, and Daniel, Mark
- Subjects
Adult ,Male ,Gerontology ,Health (social science) ,Population ,physical activity ,030209 endocrinology & metabolism ,Overweight ,Body Mass Index ,Cohort Studies ,03 medical and health sciences ,0302 clinical medicine ,History and Philosophy of Science ,Residence Characteristics ,cardiometabolic risk ,South Australia ,Prevalence ,medicine ,Humans ,overweight ,Obesity ,030212 general & internal medicine ,education ,Exercise ,Built environment ,Aged ,walkability ,Glycated Hemoglobin ,education.field_of_study ,Multilevel model ,Australia ,Middle Aged ,public open space ,built environment ,Logistic Models ,Walkability ,Cohort ,Marital status ,Environment Design ,Female ,Norm (social) ,medicine.symptom ,Psychology ,descriptive norms ,Demography - Abstract
Descriptive norms vary between places. Spatial variation in health-related descriptive norms may predict individual-level health outcomes. Such relationships have rarely been investigated. This study assessed 10-year change in glycosylated haemoglobin (HbA1c) in relation to local descriptive norms for overweight/obesity (n = 1890) and physical inactivity (n = 1906) in models accounting for features of the built environment. HbA1c was measured three times over 10 years for a population-based biomedical cohort of adults in Adelaide, South Australia. Environmental exposures were expressed for cohort participants using 1600 m road-network buffers centred on participants' residential address. Local descriptive norms (prevalence of overweight/obesity [body mass index ≥25 kg/m2] and of physical inactivity [
- Published
- 2016
91. Residential proximity to urban centres, local-area walkability and change in waist circumference among Australian adults
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Anne W. Taylor, Natasha J. Howard, Mark Daniel, Theo Niyonsenga, Neil T. Coffee, Catherine Paquet, Takemi Sugiyama, Sugiyama, Takemi, Niyonsenga, Theo, Howard, Natasha J, Coffee, Neil T, Paquet, Catherine, Taylor, Anne W, and Daniel, Mark
- Subjects
Male ,Gerontology ,Longitudinal study ,Waist ,Urban Population ,Epidemiology ,030209 endocrinology & metabolism ,Walking ,Overweight ,urban planning ,Body Mass Index ,Cohort Studies ,03 medical and health sciences ,0302 clinical medicine ,Risk Factors ,Humans ,Medicine ,City centre ,Obesity ,030212 general & internal medicine ,City Planning ,sprawl ,business.industry ,central adiposity ,Australia ,Public Health, Environmental and Occupational Health ,longitudinal study ,Urban sprawl ,Middle Aged ,Circumference ,Walkability ,Housing ,Female ,Waist Circumference ,medicine.symptom ,business ,Body mass index ,environment ,Demography - Abstract
Consistent associations have been observed between macro-level urban sprawl and overweight/obesity, but whether residential proximity to urban centres predicts adiposity change over time has not been established. Further, studies of local-area walkability and overweight/obesity have generated mixed results. This study examined 4-year change in adults' waist circumference in relation to proximity to city centre, proximity to closest suburban centre, and local-area walkability. Data were from adult participants (n = 2080) of a cohort study on chronic conditions and health risk factors in Adelaide, Australia. Baseline data were collected in 2000–03 with a follow-up in 2005–06. Multilevel regression models examined in 2015 the independent and joint associations of the three environmental measures with change in waist circumference, accounting for socio-demographic covariates. On average, waist circumference rose by 1.8 cm over approximately 4 years. Greater distance to city centre was associated with a greater increase in waist circumference. Participants living in distal areas (20 km or further from city centre) had a greater increase in waist circumference (mean increase: 2.4 cm) compared to those in proximal areas (9 km or less, mean increase: 1.2 cm). Counterintuitively, living in the vicinity of a suburban centre was associated with a greater increase in adiposity. Local-area walkability was not significantly associated with the outcome. Residential proximity to city centre appears to be protective against excessive increases in waist circumference. Controlled development and targeted interventions in the urban fringe may be needed to tackle obesity. Additional research needs to assess behaviours that mediate relationships between sprawl and obesity. Refereed/Peer-reviewed
- Published
- 2016
92. Contributions of local-area fast-food availability and are-based weight and dietary norms to 10-year change in cardiometabolic risk
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Carroll, Suzanne J, Paquet, Catherine, Howard, Natasha, Coffee, Neil, Adams, Robert, Taylor, Anne, Niyonsenga, Theo, and Daniel, Mark
- Subjects
obesity ,nutrition ,cardiometabolic risk ,body mass index ,environment - Abstract
Background: Efforts to reduce cardiometabolic disease often target individual-level risk factors. However, individual dietary behaviour and body mass index (BMI) may be influenced by the geographic patterning of food sources and local-area norms. Norms figure prominently in socio-behavioural theories yet spatial variations in norms have rarely been investigated in predicting individual health outcomes. This study assessed the contributions of fast-food availability and local-area norms for dietary behaviour and BMI to 10-year change in cardiometabolic risk. Methods: Cardiometabolic risk, expressed using a validated continuous clinical index, was calculated using data from a population-based biomedical cohort in Adelaide, South Australia over three waves of follow up, 2000—2010. Local-area exposures were defined for participants (n = 2228) using 1600m road-network buffers. Local-area norms (proportion residents with BMI ≥25 kg/m2 or not meeting fruit intake of ≥2 serves/day) were aggregated from individual-level self-reported data from a state-wide surveillance system, pooled across 2006—2010 for the study area. Fast-food availability (count of outlets) was extracted from a retail database. Separate multilevel models each featuring one local-area norm with fast-food availability as predictors of 10-year change in cardiometabolic risk were adjusted for area-level socioeconomic status and individual-level covariates. Results: In separate models including fast-food availability, greater local-area proportion of residents with BMI ≥25 kg/m2 or not meeting fruit intake of ≥2 serves/day predicted worsening cardiometabolic risk across 10-years of follow up. Fast-food availability was not related to cardiometabolic risk. There was no evidence of interaction effects between local-area exposures. Conclusions: Local-area norms (prevalence of unhealthful BMI and fruit consumption) reflect compositional population characteristics. Fast-food availability reflects built environmental context. In this study, only compositional norms, not fast-food context, predicted 10-year worsening of cardiometabolic risk. The implication of this longitudinal investigation is that the targeting of compositional norms might be more important than the targeting of fast-food context.
- Published
- 2014
93. Change over time in wealth approximated by relative residential location factor is associated with changes over time in body mass index and waist circumference
- Author
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Coffee, Neil, Howard, Natasha, Paquet, Catherine, Taylor, Anne W, Adams, Robert, Hugo, Graeme, Daniel, Mark, and Niyonsenga, Theo
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obesity ,wealth ,body mass index ,environment - Published
- 2014
94. Utility of the national death index in ascertaining mortality in acquired immunodeficiency syndrome surveillance
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Lorene M. Maddox, Mary Jo Trepka, Theophile Niyonsenga, Spencer Lieb, Trepka, Mary Jo, Maddox, Lorene M, Lieb, S, and Niyonsenga, Theo
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Adult ,Male ,Gerontology ,medicine.medical_specialty ,Pediatrics ,Adolescent ,Practice of Epidemiology ,Epidemiology ,Population ,United States Social Security Administration ,National Death Index ,Acquired immunodeficiency syndrome (AIDS) ,Confidence Intervals ,Prevalence ,medicine ,Humans ,vital statistics ,Child ,education ,population surveillance ,Cause of death ,Acquired Immunodeficiency Syndrome ,education.field_of_study ,business.industry ,Public health ,Infant, Newborn ,Infant ,registries ,acquired immunodeficiency syndrome ,Middle Aged ,medicine.disease ,mortality ,United States ,Survival Rate ,Vital Statistics ,Master file ,Child, Preschool ,Population Surveillance ,Cohort ,Florida ,Female ,Centers for Disease Control and Prevention, U.S ,business - Abstract
To assess the utility of the National Death Index (NDI) in improving the ascertainment of deaths among people diagnosed with acquired immunodeficiency syndrome (AIDS), the authors determined the number and characteristics of additional deaths identified through NDI linkage not ascertained by using standard electronic linkage with Florida Vital Records and the Social Security Administration's Death Master File. Records of people diagnosed with acquired immunodeficiency syndrome between 1993 and 2007 in Florida were linked to the NDI. The demographic characteristics and reported human immunodeficiency virus (HIV) transmission modes of people whose deaths were identified by using the NDI were compared with those whose deaths were ascertained by standard linkage methods. Of the 15,094 submitted records, 719 had confirmed matches, comprising 2.1% of known deaths (n = 34,504) within the cohort. Hispanics, males, people 40 years of age or older, and injection drug users were overrepresented among deaths ascertained only by the NDI. In-state deaths comprised 59.0% of newly identified deaths, and human immunodeficiency virus was less likely to be a cause of death among newly identified compared with previously identified deaths. The newly identified deaths were not previously ascertained principally because of slight differences in personal identifying information and could have been identified through improved linkages with Florida Vital Records. Refereed/Peer-reviewed
- Published
- 2011
95. Impact of terminal digit preference by family physicians and sphygmomanometer calibration errors on blood pressure value: Implication for hypertension screening
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Niyonsenga, Theo, Vanasse, A, Courteau, J, and Cloutier, L
- Published
- 2008
96. Hierarchical Bayesian spatiotemporal analysis of revascularization odds using smoothing splines
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Silva, G L, Dean, Caroline, Niyonsenga, Theo, and Vanasse, A
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Binomial data ,Disease mapping ,Hierarchical Bayesian model ,MCMC methods ,Spatiotemporal smoothing - Published
- 2008
97. Health Compromising Behaviors by Gender among Florida Adolescents
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Niyonsenga, Theo, Hlaing, W M, and Brown, Katrina
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- 2008
98. Local descriptive body weight and dietary norms, food availability, and 10-year change in glycosylated haemoglobin in an Australian population-based biomedical cohort
- Author
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Mark Daniel, Catherine Paquet, Robert J. Adams, Suzanne J. Carroll, Anne W. Taylor, Theo Niyonsenga, Natasha J. Howard, Neil T. Coffee, Carroll, Suzanne J, Paquet, Catherine, Howard, Natasha J, Coffee, Neil T, Adams, Robert J, Taylor, Anne W, Niyonsenga, Theo, and Daniel, Mark
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Male ,Gerontology ,Built environment ,multilevel models ,Overweight ,Food Supply ,Cohort Studies ,0302 clinical medicine ,cardiometabolic risk ,South Australia ,Prospective Studies ,030212 general & internal medicine ,education.field_of_study ,lcsh:Public aspects of medicine ,Multilevel model ,Middle Aged ,Marital status ,Female ,medicine.symptom ,0305 other medical science ,Research Article ,Cohort study ,Population ,Environment ,Descriptive norms ,03 medical and health sciences ,Environmental health ,medicine ,Humans ,food environment ,education ,Glycated Hemoglobin ,Multilevel models ,030505 public health ,business.industry ,Body Weight ,Public Health, Environmental and Occupational Health ,lcsh:RA1-1270 ,medicine.disease ,built environment ,Obesity ,Cardiometabolic risk ,Diet ,Food environment ,Norm (social) ,Biostatistics ,descriptive norms ,business ,Follow-Up Studies - Abstract
Background: Individual-level health outcomes are shaped by environmental risk conditions. Norms figure prominently in socio-behavioural theories yet spatial variations in health-related norms have rarely been investigated as environmental risk conditions. This study assessed: 1) the contributions of local descriptive norms for overweight/obesity and dietary behaviour to 10-year change in glycosylated haemoglobin (HbA1c), accounting for food resource availability; and 2) whether associations between local descriptive norms and HbA1c were moderated by food resource availability. Methods: HbA1c, representing cardiometabolic risk, was measured three times over 10 years for a population-based biomedical cohort of adults in Adelaide, South Australia. Residential environmental exposures were defined using 1600 m participant-centred road-network buffers. Local descriptive norms for overweight/obesity and insufficient fruit intake (proportion of residents with BMI ≥ 25 kg/m2 [n = 1890] or fruit intake of
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99. Effect of migrant parents' bodyweight perception on children's body bodyweight: A longitudinal analysis of population cohort study.
- Author
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Hartono S, Niyonsenga T, Cochrane T, and Kinfu Y
- Abstract
Children of migrants in Australia are disproportionally affected by overweight/obesity. Their parents, however, are likely to put little effort into lifestyle changes if unable to recognise their children's suboptimal bodyweight. We examined the potential impact of migrant parents' bodyweight perception on their children's bodyweight over time and whether the region-of-birth of parents and acculturation to the host nation's way of life moderated the relationship, as very little is known about these in the Australian context. We analysed a sample of 2046 children of migrant parents drawn from 8 waves of population-based cohort data, the Longitudinal Study of Australian Children, capturing their lived experience from ages 2 to 17. After controlling for child, parent, family, and neighbourhood factors influencing children's bodyweight, multilevel models showed higher children's bodyweight in subsequent waves if their parents perceived children's bodyweight as lower than their actual bodyweight (i.e., underestimation). However, the rate of increase in children's bodyweight attenuated over time. The effect of migrant parents' underestimation on children's subsequent bodyweight differed by region-of-birth, with higher children's bodyweight in successive waves if their parents were from the Americas, compared to migrant parents from North/West Europe. Parents' acculturation, however, did not have a discernible effect. Although migrant parents' bodyweight perception of their children's bodyweight status influenced children's bodyweight in subsequent waves, this factor was not enough to explain the extent of disparities in children's bodyweight observed in the Australian migrant population. Further research is needed to assess the effects of other types of perception (such as perceptions of healthy weight and physical exercise) on bodyweight disparities in children of migrants., Competing Interests: The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (© 2022 The Authors.)
- Published
- 2022
- Full Text
- View/download PDF
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