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A good number of adults who have self-esteem problems or suffer from anxiety and depression were raised by histrionic mothers as children. Women with histrionic personality disorder have a low level of empathy. Not only that, but they tend to relate to their children as beings who must obey without question, "objects" to be decorated and displayed to the world. Mothers with histrionic personality disorder are impatient, critical, quick to anger, and tend to occupy all of their child's intimate space. Because they are extremely sensitive to criticism themselves, mothers with histrionic personality disorder cannot accept the idea that they could be wrong. Unable to accept that they are wrong, these mothers fail to develop intellectually and emotionally beyond a certain threshold. They establish absurd rules that their child must follow, a child who - later - will notice with amazement that his mother does not respect the rule. They will treat him with indifference and withdraw his affection as a method of punishing him, scold him often, and constantly check if he follows the rules they set. The criticism will come according to the emotional fluctuations of the mothers but will be motivated otherwise, usually through a much-inflated fault of the child. Adults who have such a childhood littered with drama and criticism from their mothers will have difficulty understanding what happened in the past and why they developed in a certain way. Almost without exception, like adults, they will have frequent anxiety and low self-esteem. Some develop performance anxiety, others obsessive-compulsive personality disorder. In the case of some, their self-esteem is so damaged that they experience episodes of anger. Equally common as a result of such a difficult childhood are borderline, dependent, and avoidant personality disorders. [ABSTRACT FROM AUTHOR]

Background: The incidence of treatment resistance in schizophrenia (failure to respond to therapy with antipsychotisc) is about 20%. (Rob W. Kerwin, at all 2005). Factors that may contribute to this include: non-adherence to treatment, comorbid conditions, side effects of medication. Guidance on the duration of administration of a particular treatment, range from 2-4 weeks to several months. Some authors suggest that the absence of any decrease in the severity of symptoms within the first two weeks of therapy indicates that the patient will not relieve. Material and methods: Evaluation of alternative methods of treatment in obtaining a therapeutic response in cases considered resistant to treatment. This case study was conducted in september 2016, at one of patient with Paranoid Schizophrenia, admitted to Psychiatric Clinic, Tirgu Mures. The diagnosis was in accordance with the criteria DSM IV TR. Existential approach focused by the race of the person, the relationship between the person and the world, mental status. The collected data was clinical analysed and interpretated. Results: In the course of the disease were more treatment options with both atypical and conventional antipsychotics and: haloperidol, flupentixol, quetiapine, risperidone, aripiprazole, olanzapine, clozapine, last of them causing a remission during the last several months. Of these perspectives, treatment refractory Schizophrenia, in terms of onset reveals: resistance to treatment can exist from the onset of symptoms, can develop within five years of initiation of treatment (early onset of resistance to treatment), can develop late in the disease (late onset of treatment resistance). Conclusions: The treatment of this group of patients, resistant to treatment, remains a challenge with significant implications on public health. Augmentation of clozapine with ECT is a safe and effective method to treat refractory patients with schizophrenia. [ABSTRACT FROM AUTHOR]

The link between the cannabis use and the onset of the psychiatric disorders in people with a particular vulnerability is a subject of great importance in the medical literature. There are some gaps regarding risk factors of the phenomenon of derealization and depersonalization in patients with cannabis use. This phenomenon may be due to the presence of a genetic vulnerability of cannabinoid receptors. From a pharmacological point of view, use of cannabis does not directly produce such strong psychoactive effects to induce a dissociative state, but a high percentage of people experienced derealization or depersonalization during the first contact with this drug. Adolescence is the most affected age category. In literature, this connection between cannabis use, adolescence, and the development of depersonalization is vaguely described, but there is a link with the process of developing individual personality. Awareness of the potential effects of cannabis use is and will remain a big issue among adolescents. [ABSTRACT FROM AUTHOR]

Background: Schizophrenia is a chronic and severe mental disorder that affects how a person thinks, feels, and behaves. Cognitive deficit in schizophrenic patients is a significant mental health problem having a negative impact on overall functionality, and on therapeutic compliance. It is an important issue to patients with mental disorders, which has not been sufficiently exploited and has given rise to many controversies. The deficit may be present both at the onset and during periods of exacerbation or as part of residual symptoms. Material and methods: The study outlined in its plan to move as objectively as cognitive deficits of patients with schizophrenia. An observational study held in May 2015-May 2016. The study included 13 female and male patients diagnosed with schizophrenia (DSM-IV). Patients Were outpatients of Mental Health Center. This study was appreciated over a 12 month period. They were evaluated both during and in the relapse, remission using BACS scale (Brief Assessment of Cognition in Schizophrenia). Versions of the BACS were tested on subjects by trained psychiatrist. The relationship among the BACS measures was determined by calculating correlations among the scores. Therapeutic level of satisfaction was determined by using MSQ (Medication Satisfaction Questionar). Results: A wide range of cognitive abilities are impaired in schizophrenia, including memory, attention, speed of processing, verbal learning, executive functioning. Characteristic profile in schizophrenia: the maximum level of dysfunction include memory, attention, and executive function. The relative preservation of verbal and visual learning and memory. Cognitive performances had higher values with statistical signifiance (P < 0.05) in remission compared to those during relapse. Cognitive deficit in schizophrenia is in a close relationship with both the symptoms and satisfaction with therapy. Conclusions: The present study indicates that the BACS is a promising tool useful to assess the major constructs of cognitive function in schizophrenia patient's. [ABSTRACT FROM AUTHOR]

Background and aim Psychiatric pathology does not always start on its own but may be conditioned or triggered by a comorbidity with a high impact on the human psyche. When there are comorbidities, psychiatric pathology can occur due to the high diagnostic burden. Our study aims to find out if there is a correlation between the diagnosis of breast cancer and its severity, and psychiatric symptoms such as depressive mood, atypical anxiety, or even autolytic ideation that directly influence the quality of life of patients. Materials and methods The study is a prospective, cross-sectional, single-center study carried out between December 2023 and June 2024 at the Mureș County Clinical Hospital in Romania. The sample population had to be at least 18 years old and had to be diagnosed with breast cancer recently. We applied two tests, WHODAS 2 (World Health Organization's Disability Assessment Schedule 2.0) and level 1 (level 1 of cross-sectional measurements of symptoms), to be able to measure and aid assessment of mental health domains that are important across psychiatric diagnoses and also the degree of disability triggered by breast cancer. The statistical analysis included descriptive statistics and interferential statistics. Statistical tests, such as Shapiro-Wilk, Kruskal-Wallis, and Mann-Whitney U tests with Bonferroni correction tests, were used. The p-value was set to 0.05 with a confidence interval (CI) of 95%. Results The study included 120 women diagnosed with breast cancer, with a mean age of 56.64 ± 9.46 years. Regarding the severity of the diagnosis, 44 women (36.66%) had non-invasive cancer, 58 (48.33%) had invasive cancer, and 18 (15%) had metastases. There was a statistically significant difference between three of the five selected level 1 domains across cancer types. The WHODAS 2.0 disability scores showed a significant difference between groups (p < 0.001). Subjects with non-invasive cancer had the lowest WHODAS 2.0 score, followed by the invasive group, while metastases had the highest score. Conclusions Following the application of the two tests, level 1 and WHODAS 2.0, to our group of subjects, statistically significant differences were observed between the three categories of subjects. The degree of disability and the occurrence of psychological symptoms differed according to the severity of breast cancer. Adapting to the status of an oncological patient entails multiple changes from a psycho-emotional, social, occupational, and professional point of view. Although the most recent medications prolong survival, a holistic approach that considers psychological aspects can improve patients' long-term results., Competing Interests: Human subjects: Consent was obtained or waived by all participants in this study. Ethics Commission of the “George Emil Palade” University of Medicine, Pharmacy, Science, and Technology of Târgu Mureș issued approval 1853/13.09.2022. Animal subjects: All authors have confirmed that this study did not involve animal subjects or tissue. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work., (Copyright © 2024, Andra et al.)

Psychiatric pathology stands out in contemporary society not only as independent but also through its association with other medical comorbidities such as neoplastic diseases. Specialized literature confirms over time the coexistence of these diseases. There is a tendency to develop various psychiatric manifestations such as mood disorders and somatoform disorders, as well as decompensation of underlying existing psychiatric pathologies (anxiety disorders and psychotic disorders) or personality disorders (a good example is the exacerbation of anxiety in obsessive-compulsive personality disorder). Breast cancer, like any disabling disease, affects the person's psyche and behaviors as a whole. It is scientifically proven that mental balance influences the quality of life of patients and also the evolution and prognosis of the disease, psychological processes being able to modulate the activity of the tumor process. It is necessary to expand clinical practice and research beyond the simple evaluation of symptoms, and the goal of treatment should not only be to reduce symptoms but also to improve in terms of both physically and mentally the quality of life of cancer patients., Competing Interests: Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work., (Copyright © 2024, Andra et al.)