69 results on '"Ning-Ning Lu"'
Search Results
52. Treatment of post-liver transplant hepatic artery pseudoaneurysm with balloon angioplasty after failed stent graft placement
- Author
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Jianfeng Wang, Baojie Wei, Qiang Huang, Kun Gao, Ning-Ning Lu, and Ren-You Zhai
- Subjects
medicine.medical_specialty ,medicine.medical_treatment ,Liver transplantation ,Anastomosis ,Balloon ,Pseudoaneurysm ,Hepatic Artery ,Angioplasty ,Humans ,Medicine ,Treatment Failure ,cardiovascular diseases ,Hepatology ,business.industry ,Gastroenterology ,Stent ,Middle Aged ,medicine.disease ,Liver Transplantation ,Surgery ,surgical procedures, operative ,medicine.anatomical_structure ,cardiovascular system ,Female ,Stents ,Radiology ,business ,Complication ,Aneurysm, False ,Angioplasty, Balloon ,Artery - Abstract
Hepatic artery pseudoaneurysm is a rare complication following liver transplantation but can lead to life threatening hemorrhage if not treated effectively and in a timely manner. We describe a hepatic artery pseudoaneurysm that occurred after liver transplantation in a 53-year-old woman. The pseudoaneurysm was initially treated by implantation of a balloon-expandable covered stent-graft, but an endoleak was observed 6 days later. The endoleak was successfully resolved by further balloon angioplasty, which expanded the cylindrical stent to a conical stent, matching the anatomy of the anastomotic hepatic artery. Follow-up ultrasound examinations demonstrated patent hepatic arteries, with no evidence of pseudoaneurysm. Balloon-expandable covered stent-graft may be utilized to treat hepatic artery pseudoaneurysm following liver transplantation, due to the remodeling ability of stent-grafts, enabling them to fit the diseased vessels.
- Published
- 2012
- Full Text
- View/download PDF
53. Toxicity of Fluoranthene and Its Biodegradation by Cyclotella caspia Alga
- Author
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Ning-Ning Lu, Tiangang Luan, Yu Liu, and Chong-Yu Lan
- Subjects
Fluoranthene ,Pollutant ,biology ,Plant Science ,Biodegradation ,biology.organism_classification ,Cell morphology ,Biochemistry ,General Biochemistry, Genetics and Molecular Biology ,chemistry.chemical_compound ,chemistry ,Algae ,Chlorophyll ,Environmental chemistry ,Botany ,Caspia ,EC50 - Abstract
Fluoranthene is one of the polynuclear aromatic hydrocarbons with four benzene rings. Because of its toxicity, mutagenicity, and carcinogenicity, fluoranthene is on the black lists of 129 and 68 priority pollutants established by US Environmental Protection Agency and the People's Republic of China, respectively. In recent years, the amount of fluoranthene in the aquatic environment has been increasing with increases in anthropogenic discharge. Based on the biological investigation of tidal water in the Futian mangrove, Cyclotella caspia was selected as the dominant algal species to determine the toxicity of fluoranthene towards C. caspia alga and to investigate the biodegradation of fluoranthene by C. caspia under pure culture. The toxicity experiment showed that the 96-h EC50 value for fluoranthene was 0.2 mg/mL. Four parameters, namely C. caspia algal growth rate, chlorophyll (Chl) a content, cell morphology, and superoxide dismutase (SOD) activity, were chosen as indices of toxicity and were measured at 6 d (144 h). The results showed that: (i) the toxicity of fluoranthene towards C. caspia alga was obvious; (ii) C. caspia algal growth rate and Chl a content decreased with increasing concentrations of fluoranthene; and (iii) the rate of cell deformation and SOD activity increased with increasing concentrations of fluoranthene. The biodegradation experiment showed that: (i) the rate of physical degradation of fluoranthene was only 5.86%; (ii) the rate of biodegradation of fluoranthene on the 1st and 6th days (i.e. at 24 and 144 h) was approximately 35% and 85%, respectively; and (iii) the biodegradation capability of C. caspia alga towards fluoranthene was high. It is suggested that further investigations on the toxicity of fluoranthene towards algae, as well as on algal biodegradation mechanisms, are of great importance to use C. caspia as a biological treatment species in an organic wastewater treatment system. (Managing editor: Ping He)
- Published
- 2006
- Full Text
- View/download PDF
54. Phrenic Artery Hemorrhage after Percutaneous Portal Vein Stenting to Treat Cavernous Transformation Following Living Donor Liver Transplantation: A Case Report
- Author
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Ning-Ning Lu, Ren-You Zhai, and Qiang Huang
- Subjects
Phrenic Artery ,medicine.medical_specialty ,Percutaneous ,business.industry ,lcsh:Surgery ,Portal vein ,Case Report ,lcsh:RD1-811 ,medicine.disease ,Surgery ,Diaphragm (structural system) ,Management of Technology and Innovation ,medicine ,Portal hypertension ,Living donor liver transplantation ,Complication ,business - Abstract
Cavernous transformation is a condition which has an acutely developing harmful effect over intestinal circulation compromising the patients' life before development of portal hypertension and its results. We present the case of phrenic artery hemorrhage after successful percutaneous portal vein stenting to treat cavernous transformation following LDLT. The patient survived the hazard complication with prompt surgery. Three factors may be related to the rare complication in the case were analyzed, including affluent new vessels around the diaphragm related to LDLT procedure, high puncture site allowing the diaphragm been injured, and anticoagulation given before the puncture and soon after the procedure. Cautions should be taken for the interventional procedures in this extreme condition. Cavernous transformation is a condition which has an acutely developing harmful effect over intestinal circulation compromising the patients' life before development of portal hypertension and its results (see the work of Harmanci and Bayraktar (2007)). It is even worse when this happens in a patient after LDLT (living donor liver transplantation). Herein we have presented a case of phrenic artery hemorrhage after successful percutaneous portal vein stenting to treat cavernous transformation following LDLT. The patient survived the hazard complication with prompt surgery.
- Published
- 2011
- Full Text
- View/download PDF
55. Non-anastomotic biliary strictures following orthotopic liver transplantation: treatment with percutaneous transhepatic biliary drainage
- Author
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Renyou Zhai, Jian-Feng Wang, Kun Gao, Ning-Ning Lu, Qiang Huang, and Baojie Wei
- Subjects
Adult ,Male ,medicine.medical_specialty ,Percutaneous ,Catheters ,Orthotopic liver transplantation ,Adolescent ,Constriction, Pathologic ,Punctures ,Anastomosis ,Sepsis ,Young Adult ,Cholangiography ,medicine ,Humans ,Aged ,Retrospective Studies ,Cholestasis ,Hepatology ,medicine.diagnostic_test ,business.industry ,Bile duct ,General surgery ,Gastroenterology ,Retrospective cohort study ,General Medicine ,Middle Aged ,medicine.disease ,Dilatation ,Surgery ,Liver Transplantation ,medicine.anatomical_structure ,Treatment Outcome ,Acute pancreatitis ,Drainage ,Female ,business - Abstract
Background/aims To report our experiences with percutaneous transhepatic biliary drainage to treat non-anastomotic biliary strictures following orthotopic liver transplantation in an effort to evaluate the efficacy and safety of this procedure. Methodology From January 2002 to December 2011, forty-two consecutive patients (37 male and 5 female; aged 17-67 years, mean age 45.8 years) underwent percutaneous trans hepaticbiliary drainage for non-anastomotic biliary strictures.Twenty-six of them underwent percutaneous trans hepatic biliary drainage through right bile duct, 15 under-went bilateral (right bile duct and left bile duct) percutaneous transhepatic biliary drainage with 12 patients through left bile duct in the second procedure, the remaining one underwent percutaneous transhepatic biliary drainage through the left bile duct alone. Results Percutaneous transhepatic biliary drainage was successfully completed in all 42 patients, 23 of whom gained treatment success after first procedure. The other 19 patients underwent percutaneous transhepatic biliary drainage for the second time and 15 of them were successfully treated, the total success rate was 90.5% (38 in 42 cases). Procedure related complications were observed in 4 patients including cholangitis, sepsis, bleeding and acute pancreatitis. Conclusions Percutaneous transhepatic biliary drainage ap-pears to be an effective and safe treatment with high technical success rate and few major complications for non-anastomotic biliary strictures following orthotopic liver transplantation.
- Published
- 2012
56. Taxonomic status of Chinese bahaba (Bahaba taipingensis) and its phylogenetic relationship with other species in the family Sciaenidae
- Author
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Xi-Guo Li, Dong-Fang Sun, Ning-Ning Lu, Yong-Zheng Li, Wei He, and Wei-Hua Lu
- Subjects
Mitochondrial DNA ,China ,Subfamily ,Phylogenetic tree ,Cytochrome b ,Zoology ,Bayes Theorem ,Genes, rRNA ,Sequence Analysis, DNA ,Sciaenidae ,Biology ,Cytochromes b ,Mitochondria ,Perciformes ,Species Specificity ,Phylogenetics ,RNA, Ribosomal, 16S ,Molecular phylogenetics ,Genetics ,Animals ,Taxonomy (biology) ,Molecular Biology ,Phylogeny - Abstract
Sciaenidae is one of the largest fish families, but the phylogeny and taxonomy of these fishes are still being disputed. Furthermore, the taxonomic status of the Chinese bahaba (Bahaba taipingensis), which is an endemic species to China, had never been studied through molecular method. In this study, phylogenetic relationships among sciaenid species were reconstructed using DNA sequence data from the mitochondrial cytochrome b (cyt b) gene and the 16S ribosomal RNA (16S rRNA) gene through Bayesian inference (BI) analyses. The phylogenetic trees indicated that the Chinese bahaba closely related to Collichthys and Pseudosciaena. Previous studies (Meng et al. 2004. Prog Nat Sci 14(5):514-521, [in Chinese]) showed that the subfamily Pseudosciaeninae represented the latest evolutionary sort, which was more suitable with the current environment. Based on our 16S rRNA, the Chinese bahaba showed close relationship with Pseudosciaena, thus the divergence of the Chinese bahaba maybe also very late within the family Sciaenidae. It was probably that the oceanographic or ecological discontinuities of these species vary considerably causing particularly strong breaks. Furthermore, combined with previous studies, we suggested that there was only one genus, Otolithes, within the subfamily Otolithinae. Nevertheless, the taxonomic status of the Chinese bahaba and the phylogeny of the whole family were not completely solved. Additional samples of more species are required to develop a clearer picture of the evolutionary history of Sciaenidae.
- Published
- 2012
57. A new probabilistic packet marking technology based on path identification
- Author
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Hongke Zhang, Huachun Zhou, and Ning-ning Lu
- Subjects
Routing protocol ,Router ,Identification scheme ,business.industry ,Computer science ,Network packet ,Distributed computing ,ComputerSystemsOrganization_COMPUTER-COMMUNICATIONNETWORKS ,Hash function ,Probabilistic logic ,Denial-of-service attack ,Data_CODINGANDINFORMATIONTHEORY ,Identification (information) ,Path (graph theory) ,The Internet ,business ,Computer network - Abstract
In the article, we proposed a new probabilistic packet marking technology (called as P3M) based on path identification to defense serious distributed denial of service attacks and solve complex computation and other problem existed in traditional probabilistic packet marking (PPM) technologies. Our first contribution is constructing a new payload to carry router address and path identification. The second contribution is designing a new path identification scheme based on router addresses and hash algorithm. Our research indicates that comparing with based PPM, advanced PPM and other traditional PPM technologies, P3M has lower computation complexity and its response is faster. P3M is a practical technology to defense DDoS.
- Published
- 2009
- Full Text
- View/download PDF
58. The Effectiveness of Passport Source Address Validation Scheme
- Author
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Huachun Zhou, Ning-ning Lu, and Hongke Zhang
- Subjects
Scheme (programming language) ,Spoofing attack ,business.industry ,Computer science ,media_common.quotation_subject ,Vertex cover ,Graph theory ,Network topology ,Computer security ,computer.software_genre ,ComputingMilieux_COMPUTERSANDSOCIETY ,The Internet ,business ,Function (engineering) ,computer ,Source address ,computer.programming_language ,media_common - Abstract
Passport is a new secure and adoptable source address validation technique, which has attracted fully attention. In this article, we research into the efficiency of Passport. First of all, we build a mathematical model to describe Passport’s function, then propose an evaluating indexes, at last we use Brite generate a Power-Law network topology and design correlative algorithm to quantitative analysis Passport’s efficiency. The study shows that: (1) Comparing with randomly deploying, the efficiency of Vertex Cover deploying is even higher; (2) Only deploying Passport in 54.3% AS can effectively defend the whole Internet against source address spoofing, although Passport will still cause large overload, it has been the most effectiveness source address validation scheme at recently.
- Published
- 2009
- Full Text
- View/download PDF
59. A New Source Address Validation Scheme Based on IBS
- Author
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Hongke Zhang, Ning-ning Lu, and Huachun Zhou
- Subjects
Routing protocol ,Scheme (programming language) ,Authentication ,business.industry ,Network security ,Computer science ,law.invention ,Public-key cryptography ,Digital signature ,law ,Internet Protocol ,The Internet ,business ,computer ,computer.programming_language ,Computer network - Abstract
Source address authentication is very important to change current serious network security situation. In this article, we propose a new source address validation scheme based on IBS algorithm and study its security using SVO logic. We find that our scheme can successfully guarantees authenticity of IP packet’s information source.
- Published
- 2009
- Full Text
- View/download PDF
60. Ultrasonication-assisted one-step self-assembly preparation of biocompatible fluorescent-magnetic nanobeads for rare cancer cell detection
- Author
-
Xue-Ying Wang, Min Xie, Yu-Qi Chen, Wei-Ping Sui, Shan Guo, and Ning-Ning Lu
- Subjects
Streptavidin ,Materials science ,Biocompatibility ,Sonication ,Nanoparticle ,Bioengineering ,Nanotechnology ,Nanomaterials ,chemistry.chemical_compound ,Quantum Dots ,Amphiphile ,Humans ,General Materials Science ,Electrical and Electronic Engineering ,Magnetite Nanoparticles ,Chitosan ,Bioconjugation ,Epidermal Growth Factor ,Mechanical Engineering ,General Chemistry ,Neoplastic Cells, Circulating ,chemistry ,Mechanics of Materials ,MCF-7 Cells ,HeLa Cells ,Superparamagnetism - Abstract
Multifunctional nanomaterials simultaneously possessing attractive properties, such as strong fluorescent intensity, excellent superparamagnetic behavior, easy modification and good biocompatibility, are always desired in a wide range of applications. In this work, we present a facile ultrasonication-assisted one-step self-assembly strategy for the fabrication of smart fluorescent-magnetic nanobeads (FMNBs) without using a matrix. Via one-step ultrasonication, organic-soluble superparamagnetic nanoparticles (MNPs) and quantum dots (QDs) were automatically encapsulated by amphiphilic (2-hydroxyl-3-dodecanoxyl) propylcarboxymethylchitosans (HDP-CMCHSs) through hydrophobic interaction to form hydrophilic FMNBs, presenting a good QD fluorescent property and a strong MNP magnetic response. The outer surface of the FMNBs was derived from natural biopolymer chitosans, enabling FMNBs with good biocompatibility and convenience for biological modification. As-prepared FMNBs can be easily modified with streptavidin, facilitating bioconjugation with biotin-labeled human epidermal growth factor (hEGF). hEGF-functionalized FMNBs are able to specifically recognize and capture rare target cells spiked in white blood cells, and the recovered cells can be further cultured for a long time. All of these excellent properties make nanobeads promising for circulating tumor cell (CTC) detection.
- Published
- 2014
- Full Text
- View/download PDF
61. A New Source Address Validation Scheme Based on IBS.
- Author
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Ning-ning Lu, Hua-chun Zhou, and Hong-ke Zhang
- Published
- 2009
- Full Text
- View/download PDF
62. The Effectiveness of Passport Source Address Validation Scheme.
- Author
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Ning-ning Lu, Hua-chun Zhou, and Hong-ke Zhang
- Published
- 2009
- Full Text
- View/download PDF
63. Toxicity of Fluoranthene and Its Biodegradation by Cyclotella caspia Alga.
- Author
-
Yu Liu, Tian-Gang Luan, Ning-Ning Lu, and Chong-Yu Lan
- Subjects
BIODEGRADATION ,BIODEGRADATION of plant litter ,WASTEWATER treatment ,ALGAE ,AQUATIC resources ,ORGANIC water pollutants ,WATER pollution - Abstract
Fluoranthene is one of the polynuclear aromatic hydrocarbons with four benzene rings. Because of its toxicity, mutagenicity, and carcinogenicity, fluoranthene is on the black lists of 129 and 68 priority pollutants established by US Environmental Protection Agency and the People's Republic of China, respectively. In recent years, the amount of fluoranthene in the aquatic environment has been increasing with increases in anthropogenic discharge. Based on the biological investigation of tidal water in the Futian mangrove, Cyclotella caspia was selected as the dominant algal species to determine the toxicity of fluoranthene towards C. caspia alga and to investigate the biodegradation of fluoranthene by C. caspia under pure culture. The toxicity experiment showed that the 96-h EC
50 value for fluoranthene was 0.2 mg/mL. Four parameters, namely C. caspia algal growth rate, chlorophyll (Chl) a content, cell morphology, and superoxide dismutase (SOD) activity, were chosen as indices of toxicity and were measured at 6 d (144 h). The results showed that: (i) the toxicity of fluoranthene towards C. caspia alga was obvious; (ii) C. caspia algal growth rate and Chl a content decreased with increasing concentrations of fluoranthene; and (iii) the rate of cell deformation and SOD activity increased with increasing concentrations of fluoranthene. The biodegradation experiment showed that: (i) the rate of physical degradation of fluoranthene was only 5.86%; (ii) the rate of biodegradation of fluoranthene on the 1st and 6th days (i.e. at 24 and 144 h) was approximately 35% and 85%, respectively; and (iii) the biodegradation capability of C. caspia alga towards fluoranthene was high. It is suggested that further investigations on the toxicity of fluoranthene towards algae, as well as on algal biodegradation mechanisms, are of great importance to use C. caspia as a biological treatment species in an organic wastewater treatment system. (Managing editor: Ping He) [ABSTRACT FROM AUTHOR]- Published
- 2006
- Full Text
- View/download PDF
64. Preoperative IMRT With Concurrent Apatinib for Localised Extremity or Trunk Sarcoma
- Author
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Ning-Ning Lu, Principle Investigator
- Published
- 2022
65. Preoperative Ultra-hypofractionated Radiotherapy Followed by Surgery for Retroperitoneal Sarcoma
- Author
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Ning-Ning Lu, Principle Investigator
- Published
- 2022
66. MR-linac Guided Ultra-hypofractionated RT for Prostate Cancer
- Author
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Ning-Ning Lu, Principle Investigator
- Published
- 2021
67. Preoperative IMRT With Concurrent Anlotinib for Localised Extremity or Trunk Sarcoma
- Author
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Ning-Ning Lu, Principle Investigator
- Published
- 2021
68. Ultrasonication-assisted one-step self-assembly preparation of biocompatible fluorescent-magnetic nanobeads for rare cancer cell detection.
- Author
-
Shan Guo, Yu-Qi Chen, Ning-Ning Lu, Xue-Ying Wang, Min Xie, and Wei-Ping Sui
- Subjects
NANOSTRUCTURED materials ,CANCER cells ,NANOPARTICLES ,QUANTUM dots ,BIOPOLYMERS - Abstract
Multifunctional nanomaterials simultaneously possessing attractive properties, such as strong fluorescent intensity, excellent superparamagnetic behavior, easy modification and good biocompatibility, are always desired in a wide range of applications. In this work, we present a facile ultrasonication-assisted one-step self-assembly strategy for the fabrication of smart fluorescent-magnetic nanobeads (FMNBs) without using a matrix. Via one-step ultrasonication, organic-soluble superparamagnetic nanoparticles (MNPs) and quantum dots (QDs) were automatically encapsulated by amphiphilic (2-hydroxyl-3-dodecanoxyl) propylcarboxymethylchitosans (HDP-CMCHSs) through hydrophobic interaction to form hydrophilic FMNBs, presenting a good QD fluorescent property and a strong MNP magnetic response. The outer surface of the FMNBs was derived from natural biopolymer chitosans, enabling FMNBs with good biocompatibility and convenience for biological modification. As-prepared FMNBs can be easily modified with streptavidin, facilitating bioconjugation with biotin-labeled human epidermal growth factor (hEGF). hEGF-functionalized FMNBs are able to specifically recognize and capture rare target cells spiked in white blood cells, and the recovered cells can be further cultured for a long time. All of these excellent properties make nanobeads promising for circulating tumor cell (CTC) detection. [ABSTRACT FROM AUTHOR]
- Published
- 2014
- Full Text
- View/download PDF
69. Clinical implications of plasma Epstein-Barr virus DNA in early-stage extranodal nasal-type NK/T-cell lymphoma patients receiving primary radiotherapy.
- Author
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Zhao-Yang Wang, Qing-Feng Liu, Hua Wang, Jing Jin, Wei-Hu Wang, Shu-Lian Wang, Yong-Wen Song, Yue-Ping Liu, Hui Fang, Hua Ren, Run-Ye Wu, Bo Chen, Xi-Mei Zhang, Ning-Ning Lu, Li-Qiang Zhou, and Ye-Xiong Li
- Subjects
- *
EPSTEIN-Barr virus , *VIRAL genomes , *KILLER cells , *T-cell lymphoma , *CANCER radiotherapy , *SYMPTOMS , *LACTATE dehydrogenase , *THERAPEUTICS - Abstract
The clinical value of plasma Epstein-Barr virus (EBV) DNA has not been evaluated in patients with early-stage extranodal nasal-type NK/T-cell lymphoma (NKTCL) receiving primary radiotherapy. Fifty-eight patients with stage I disease and 11 with stage II disease were recruited. High pretreatment EBV-DNA concentrations were associated with B-symptoms, elevated lactate dehydrogenase levels, and a high International Prognostic Index score. EBV-DNA levels significantly decreased after treatment. The 3-year overall survival (OS) rate was 82.6% for all patients. Stage I or II patients with a pretreatment EBV-DNA level of ≤ 500 copies/mL had 3-year OS and progression-free survival (PFS) rates of 97.1% and 79.0%, respectively, compared with 66.3% (P = .002) and 52.2% (P = .045) in patients with EBV-DNA levels of > 500 copies/mL. The 3-year OS and PFS rates for patients with undetectable EBV-DNA after treatment was significantly higher than patients with detectable EBV-DNA (OS, 92.0% vs 69.8%, P = .031; PFS, 77.5% vs 50.7%, P = .028). Similar results were observed in stage I patients. EBV-DNA levels correlate with tumor load and a poorer prognosis in early-stage NKTCL. The circulating EBV-DNA level could serve both as a valuable biomarker of tumor load for the accurate classification of early-stage NKTCL and as a prognostic factor. [ABSTRACT FROM AUTHOR]
- Published
- 2012
- Full Text
- View/download PDF
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