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The AIDS epidemic with severe opportunistic infections has put a heavy demand to health workers. The existence of associated renal disorder--acute renal failure or rapidly progressive azotaemia with histological lesion of focal and segmental glomerulosclerosis complicates it even more. We treated a 29-year-old male patient with AIDS (Gr.IV/C-2), who was intravenous heroin abuser with progressed azotaemia, anaemia and thrombocytopenia. Because of unsolved questions of acute renal disease or chronic damage, treatment was started with peritoneal dialysis, including all other conservative measures. Results were good, and during the seven month therapy no episode of peritonitis was observed. Such a result is satisfactory for patients with initial renal disease, and excellent for a person with acquired immunodeficiency syndrome. The cause of death was not connected with renal disease and dialysis, but was due to AIDS. According to middle proteinuria, hypertension and rapid progession of azotaemia our patient probably belonged to the group of patient with chornic renal disease due to AIDS.

Captopril and Enalapril, angiotensin converting enzyme inhibitors, were used in the treatment of grave renal hypertension. The treatment concerned 40 randomly selected patients with the average creatinine clearance of 55.7 ml/min. The patients were divided in two groups: the first groups was ril. The good regulation of blood pressure was achieved only in combination with furosemide and protreated with captopril and the second with enalappranolol. Furosemide was given to all patients, and propranolol to all treated with captopril and to 12 subjects treated with enalapril. The angiotensin converting enzyme increased plasma renine activity and decreased aldosterone concentration in the serum. No change in renal function was noted. Proteinuria was decreased. Side-effects were manifest in two patients only treated with captopril. In conclusion it can be said that angiotensin converting enzyme inhibitors are efficient in the treatment of renal hypertension.