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398 results on '"Nakashima, Taku"'

51. First‐line osimertinib treatment in a patient with lung adenocarcinoma with coexisting epidermal growth factor receptorG719S and de novo T790M mutations

Author

Ito, Noriaki, primary, Masuda, Takeshi, additional, Ooka, Ikuko, additional, Hosoya, Takatsune, additional, Yamaguchi, Kakuhiro, additional, Sakamoto, Shinjiro, additional, Horimasu, Yasushi, additional, Nakashima, Taku, additional, Miyamoto, Shintaro, additional, Iwamoto, Hiroshi, additional, Fujitaka, Kazunori, additional, Hamada, Hironobu, additional, and Hattori, Noboru, additional

Published
2022
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52. Primary Pulmonary Mucosa-associated Lymphoid Tissue Lymphoma with the High Expression of IgG4: A Case Report

Author

Tanahashi, Hiroki, primary, Yamaguchi, Kakuhiro, additional, Koura, Tomoko, additional, Kambara, Takahiro, additional, Yamada, Kyohei, additional, Sakamoto, Shinjiro, additional, Horimasu, Yasushi, additional, Masuda, Takeshi, additional, Miyamoto, Shintaro, additional, Nakashima, Taku, additional, Iwamoto, Hiroshi, additional, Fukushima, Noriyasu, additional, Fujitaka, Kazunori, additional, Hamada, Hironobu, additional, Ichinohe, Tatsuo, additional, Ohshima, Koichi, additional, and Hattori, Noboru, additional

Published
2022
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53. Dupilumab as an adjunct treatment for a patient with steroid-dependent immunoglobulin G4-related disease complicated by asthma: a case report

Author

Otani,, Toshihito, primary, Iwamoto,, Hiroshi, additional, Yoshida,, Yusuke, additional, Yamaguchi,, Kakuhiro, additional, Sakamoto,, Shinjiro, additional, Horimasu,, Yasushi, additional, Masuda,, Takeshi, additional, Miyamoto,, Shintaro, additional, Nakashima,, Taku, additional, Fujitaka,, Kazunori, additional, Hamada,, Hironobu, additional, Hirata,, Shintaro, additional, Sugiyama,, Eiji, additional, and Hattori,, Noboru, additional

Published
2021
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54. Dupilumab as an adjunct treatment for a patient with steroid-dependent immunoglobulin G4-related disease complicated by asthma: a case report.

Author

Otani, Toshihito, Iwamoto, Hiroshi, Yoshida, Yusuke, Yamaguchi, Kakuhiro, Sakamoto, Shinjiro, Horimasu, Yasushi, Masuda, Takeshi, Miyamoto, Shintaro, Nakashima, Taku, Fujitaka, Kazunori, Hamada, Hironobu, Hirata, Shintaro, Sugiyama, Eiji, and Hattori, Noboru

Subjects
DUPILUMAB, ASTHMA, PREDNISOLONE, PAROTID glands, COUGH, THERAPEUTICS
Abstract

Introduction: Immunoglobulin G4-related disease (IgG4-RD) responds well to glucocorticoids but is often associated with relapses. Interleukin (IL)-4 and IL-13 are involved in the pathogenesis of IgG4-RD. We present the first case in which dupilumab was an effective adjunct treatment for a patient with steroid-dependent IgG4-RD complicated by asthma.Case study: A 57-year-old man was referred to our hospital for further investigation and treatment of proptosis with neck swelling in 2019. He developed a cough and swelling of the neck in 2016. He was diagnosed with asthma in 2017 and started receiving inhaled glucocorticoids and a long-acting beta-agonist. The patient started receiving oral prednisolone at a dose of 20 mg/day. Oral prednisolone reduced his symptoms, but he relapsed when treatment was tapered to less than 10 mg/day. He was diagnosed with IgG4-RD through a parotid gland biopsy.Results: Azathioprine was given to reduce systemic glucocorticoids. The prednisolone dose was gradually tapered to 10 mg/day, resulting in the relapse of proptosis and an asthma attack. We added dupilumab, and his asthma symptoms and proptosis improved. Serum IgG4 levels continued to decrease, and the prednisolone dose was tapered to 2 mg.Conclusion: Dupilumab might be useful as an adjunctive treatment for patients with steroid-dependent IgG4-RD complicated by asthma. Serum IgG4 levels can be used as a marker to monitor dupilumab treatment in IgG4-RD. [ABSTRACT FROM AUTHOR]

Published
2022
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56. Pneumatosis Intestinalis following Radiation Esophagitis during Chemoradiotherapy for Lung Cancer: A Case Report

Author

Ito, Noriaki, primary, Masuda, Takeshi, additional, Yamaguchi, Kakuhiro, additional, Sakamoto, Shinjiro, additional, Horimasu, Yasushi, additional, Nakashima, Taku, additional, Miyamoto, Shintaro, additional, Iwamoto, Hiroshi, additional, Fujitaka, Kazunori, additional, Hamada, Hironobu, additional, and Hattori, Noboru, additional

Published
2021
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57. Tolerability and efficacy of IMpower133 regimen modified for dialysis patients with extensive‐stage small cell lung cancer: Two case reports

Author

Watari, Naokazu, primary, Yamaguchi, Kakuhiro, additional, Masuda, Takeshi, additional, Ito, Noriaki, additional, Sakamoto, Shinjiro, additional, Horimasu, Yasushi, additional, Miyamoto, Shintaro, additional, Nakashima, Taku, additional, Iwamoto, Hiroshi, additional, Fujitaka, Kazunori, additional, Hamada, Hironobu, additional, and Hattori, Noboru, additional

Published
2021
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58. Accelerated decline in lung function in adults with a history of remitted childhood asthma

Author

Miura, Shinichiro, primary, Iwamoto, Hiroshi, additional, Omori, Keitaro, additional, Yamaguchi, Kakuhiro, additional, Sakamoto, Shinjiro, additional, Horimasu, Yasushi, additional, Masuda, Takeshi, additional, Miyamoto, Shintaro, additional, Nakashima, Taku, additional, Fujitaka, Kazunori, additional, Hamada, Hironobu, additional, Yokoyama, Akihito, additional, and Hattori, Noboru, additional

Published
2021
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60. MO10-2 Association of pre-existing interstitial lung abnormalities with immune checkpoint inhibitor-induced interstitial lung disease among patients with non-lung cancers

Author

Shimoji, Kiyofumi, primary, Masuda, Takeshi, additional, Yamaguchi, Kakuhiro, additional, Sakamoto, Shinjiro, additional, Horimasu, Yasushi, additional, Nakashima, Taku, additional, Miyamoto, Shintaro, additional, Iwamoto, Hiroshi, additional, Fujitaka, Kazunori, additional, Hamada, Hironobu, additional, Takeno, Sachio, additional, Hide, Michihiro, additional, Teishima, Jun, additional, Ohdan, Hideki, additional, and Hattori, Noboru, additional

Published
2021
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61. IL-18 binding protein can be a prognostic biomarker for idiopathic pulmonary fibrosis

Author

Nakanishi, Yu, primary, Horimasu, Yasushi, additional, Yamaguchi, Kakuhiro, additional, Sakamoto, Shinjiro, additional, Masuda, Takeshi, additional, Nakashima, Taku, additional, Miyamoto, Shintaro, additional, Iwamoto, Hiroshi, additional, Ohshimo, Shinichiro, additional, Fujitaka, Kazunori, additional, Hamada, Hironobu, additional, and Hattori, Noboru, additional

Published
2021
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62. Prognostic Significance of EGFR Gene Mutation in Patients With EGFR Mutated Non-small Cell Lung Cancer Who Received Best Supportive Care Alone

Author

MASUDA, TAKESHI, primary, WAKABAYASHI, YU, additional, NAKASHIMA, TAKU, additional, NISHIMURA, YOSHIFUMI, additional, SHIMOJI, KIYOFUMI, additional, YAMAGUCHI, KAKUHIRO, additional, SAKAMOTO, SHINJIRO, additional, HORIMASU, YASUSHI, additional, MIYAMOTO, SHINTARO, additional, SENOO, TADASHI, additional, IWAMOTO, HIROSHI, additional, OHSHIMO, SHINICHIRO, additional, FUJITAKA, KAZUNORI, additional, HAMADA, HIRONOBU, additional, and HATTORI, NOBORU, additional

Published
2021
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63. Additional file 3 of Human bone marrow-derived mesenchymal stromal cells cultured in serum-free media demonstrate enhanced antifibrotic abilities via prolonged survival and robust regulatory T cell induction in murine bleomycin-induced pulmonary fibrosis

Author

Takao, Shun, Nakashima, Taku, Masuda, Takeshi, Namba, Masashi, Sakamoto, Shinjiro, Yamaguchi, Kakuhiro, Horimasu, Yasushi, Miyamoto, Shintaro, Iwamoto, Hiroshi, Fujitaka, Kazunori, Hamada, Hironobu, Takahashi, Shinya, Nakashima, Ayumu, and Hattori, Noboru

Abstract

Additional file 3: Cytokine levels in BALF before BLM OA or at 7 or 14 days after BLM OA (n = 5–8 per group). Data are presented as the mean ± SD for normal distribution (IL-13), or as the median with interquartile range for non-normal distribution (TNF-α, IL-4, IL-5, IL-10).

Published
2021
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64. Additional file 5 of Antifibrotic effect of lung-resident progenitor cells with high aldehyde dehydrogenase activity

Author

Takahashi, Hiroshi, Nakashima, Taku, Masuda, Takeshi, Namba, Masashi, Sakamoto, Shinjiro, Yamaguchi, Kakuhiro, Horimasu, Yasushi, Miyamoto, Shintaro, Iwamoto, Hiroshi, Fujitaka, Kazunori, Hamada, Hironobu, and Hattori, Noboru

Subjects
respiratory system, respiratory tract diseases
Abstract

Additional file 5. ALDH1a1 immunostaining in lung tissue. Representative images of ALDH1a1 immunostaining in PBS- or BLM-treated lung tissue sections on day 14.

Published
2021
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65. Additional file 9 of Human bone marrow-derived mesenchymal stromal cells cultured in serum-free media demonstrate enhanced antifibrotic abilities via prolonged survival and robust regulatory T cell induction in murine bleomycin-induced pulmonary fibrosis

Author

Takao, Shun, Nakashima, Taku, Masuda, Takeshi, Namba, Masashi, Sakamoto, Shinjiro, Yamaguchi, Kakuhiro, Horimasu, Yasushi, Miyamoto, Shintaro, Iwamoto, Hiroshi, Fujitaka, Kazunori, Hamada, Hironobu, Takahashi, Shinya, Nakashima, Ayumu, and Hattori, Noboru

Subjects
sense organs, respiratory system
Abstract

Additional file 9: Lung homogenate was generated from the left lung of mice at 7 days after PBS OA (DAMP- group) or BLM OA (DAMP+ group). Upper inserts (pore size, 0.4 μm; Corning) with cultured lung homogenates were dipped into the basal plate of MSCs (1.0 × 105 cells/well) cultured in DMEM with 10% FBS (S-MSCs) or in serum-free STK2 media (SF-MSCs). After 72 hours, the MSCs were harvested, and intracellular proteins were extracted for TGF-β1 measurement. TGF-β1 was measured using an ELISA kit. Data were calculated as a TGF-β1 per each number of live MSCs in the culture media, and expressed as a percentage of the mean in DAMP- group. Data are presented as means ± SD (n = 3 per group).

Published
2021
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66. Additional file 7 of Antifibrotic effect of lung-resident progenitor cells with high aldehyde dehydrogenase activity

Author

Takahashi, Hiroshi, Nakashima, Taku, Masuda, Takeshi, Namba, Masashi, Sakamoto, Shinjiro, Yamaguchi, Kakuhiro, Horimasu, Yasushi, Miyamoto, Shintaro, Iwamoto, Hiroshi, Fujitaka, Kazunori, Hamada, Hironobu, and Hattori, Noboru

Subjects
congenital, hereditary, and neonatal diseases and abnormalities, urogenital system, nutritional and metabolic diseases
Abstract

Additional file 7. CD45−/ALDHbr cell therapy ameliorates BLM-induced pulmonary fibrosis. Masson’s trichrome staining of lung tissue sections obtained on day 14 from BLM-treated mice transferred with CD45−/ALDHdim and CD45−/ALDHbr cells.

Published
2021
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67. Additional file 1 of Human bone marrow-derived mesenchymal stromal cells cultured in serum-free media demonstrate enhanced antifibrotic abilities via prolonged survival and robust regulatory T cell induction in murine bleomycin-induced pulmonary fibrosis

Author

Takao, Shun, Nakashima, Taku, Masuda, Takeshi, Namba, Masashi, Sakamoto, Shinjiro, Yamaguchi, Kakuhiro, Horimasu, Yasushi, Miyamoto, Shintaro, Iwamoto, Hiroshi, Fujitaka, Kazunori, Hamada, Hironobu, Takahashi, Shinya, Nakashima, Ayumu, and Hattori, Noboru

Subjects
sense organs
Abstract

Additional file 1: Representative flow cytometry analysis related to the defined positive and negative MSC surface markers on MSCs cultured in DMEM with 10% FBS (S-MSC) or in serum-free STK2 medium (SF-MSC).

Published
2021
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68. Additional file 4 of Human bone marrow-derived mesenchymal stromal cells cultured in serum-free media demonstrate enhanced antifibrotic abilities via prolonged survival and robust regulatory T cell induction in murine bleomycin-induced pulmonary fibrosis

Author

Takao, Shun, Nakashima, Taku, Masuda, Takeshi, Namba, Masashi, Sakamoto, Shinjiro, Yamaguchi, Kakuhiro, Horimasu, Yasushi, Miyamoto, Shintaro, Iwamoto, Hiroshi, Fujitaka, Kazunori, Hamada, Hironobu, Takahashi, Shinya, Nakashima, Ayumu, and Hattori, Noboru

Subjects
congenital, hereditary, and neonatal diseases and abnormalities, urogenital system, nutritional and metabolic diseases
Abstract

Additional file 4: Cytokine levels in serum before BLM OA or at 4, 7, 14, or 21 days after BLM OA (n = 3–7 per group). Data are presented as the median with interquartile range.

Published
2021
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69. Additional file 2 of Human bone marrow-derived mesenchymal stromal cells cultured in serum-free media demonstrate enhanced antifibrotic abilities via prolonged survival and robust regulatory T cell induction in murine bleomycin-induced pulmonary fibrosis

Author

Takao, Shun, Nakashima, Taku, Masuda, Takeshi, Namba, Masashi, Sakamoto, Shinjiro, Yamaguchi, Kakuhiro, Horimasu, Yasushi, Miyamoto, Shintaro, Iwamoto, Hiroshi, Fujitaka, Kazunori, Hamada, Hironobu, Takahashi, Shinya, Nakashima, Ayumu, and Hattori, Noboru

Abstract

Additional file 2: Fluorescence microscopic ex vivo images of engrafted DiI-labeled SF-MSCs (yellow arrows) in murine lungs on the day after injection.

Published
2021
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71. Additional file 6 of Antifibrotic effect of lung-resident progenitor cells with high aldehyde dehydrogenase activity

Author

Takahashi, Hiroshi, Nakashima, Taku, Masuda, Takeshi, Namba, Masashi, Sakamoto, Shinjiro, Yamaguchi, Kakuhiro, Horimasu, Yasushi, Miyamoto, Shintaro, Iwamoto, Hiroshi, Fujitaka, Kazunori, Hamada, Hironobu, and Hattori, Noboru

Subjects
cardiovascular system, respiratory system
Abstract

Additional file 6. Double staining of ALDHbr cells and side population cells in lung tissue. (A) Representative image of lung CD45−/CD31−/ALDHbr live cells. (B) Representative image of lung CD45−/CD31−/Hoechstdim (side population, SP) live cells. (C) The gating of SP cells was confirmed using verapamil, which is an inhibitor for Hoechst staining. (D) SP cells in lung CD45−/CD31−/ALDHbr live cells. (E) ALDHbr cells in SP cells.

Published
2021
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72. Additional file 4 of Antifibrotic effect of lung-resident progenitor cells with high aldehyde dehydrogenase activity

Author

Takahashi, Hiroshi, Nakashima, Taku, Masuda, Takeshi, Namba, Masashi, Sakamoto, Shinjiro, Yamaguchi, Kakuhiro, Horimasu, Yasushi, Miyamoto, Shintaro, Iwamoto, Hiroshi, Fujitaka, Kazunori, Hamada, Hironobu, and Hattori, Noboru

Abstract

Additional file 4. Expression of cell surface proteins in CD45−/ALDHdim cells and CD45−/ALDHbr cells. Sorted CD45−/ALDHdim cells and CD45−/ALDHbr cells were examined for cell surface markers associated with mesenchymal stem cells (MSCs), fibroblasts, and stem cells.

Published
2021
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73. Additional file 8 of Antifibrotic effect of lung-resident progenitor cells with high aldehyde dehydrogenase activity

Author

Takahashi, Hiroshi, Nakashima, Taku, Masuda, Takeshi, Namba, Masashi, Sakamoto, Shinjiro, Yamaguchi, Kakuhiro, Horimasu, Yasushi, Miyamoto, Shintaro, Iwamoto, Hiroshi, Fujitaka, Kazunori, Hamada, Hironobu, and Hattori, Noboru

Abstract

Additional file 8. Discrimination of mCherry-heterozygotic mouse. DNA extracted from the tails of mice was amplified by PCR using primers shown in Table S2. The expression of the mCherry-heterozygotic band was evaluated using agarose gel electrophoresis.

Published
2021
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74. Additional file 3 of Antifibrotic effect of lung-resident progenitor cells with high aldehyde dehydrogenase activity

Author

Takahashi, Hiroshi, Nakashima, Taku, Masuda, Takeshi, Namba, Masashi, Sakamoto, Shinjiro, Yamaguchi, Kakuhiro, Horimasu, Yasushi, Miyamoto, Shintaro, Iwamoto, Hiroshi, Fujitaka, Kazunori, Hamada, Hironobu, and Hattori, Noboru

Abstract

Additional file 3. Effect of magnetic-activated cell sorting for the enrichment of CD45−/ALDHbr cells. Representative image of lung CD45−/ALDHbr cells before and after magnetic-activated cell sorting using the Tissue Stem Cell Pre-Enrichment Kit. ALDHbr gating was determined by comparing samples stained with ALDEFLUOR alone and with ALDEFLUOR and diethylaminobenzaldehyde (DEAB), an ALDH inhibitor.

Published
2021
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75. Additional file 8 of Human bone marrow-derived mesenchymal stromal cells cultured in serum-free media demonstrate enhanced antifibrotic abilities via prolonged survival and robust regulatory T cell induction in murine bleomycin-induced pulmonary fibrosis

Author

Takao, Shun, Nakashima, Taku, Masuda, Takeshi, Namba, Masashi, Sakamoto, Shinjiro, Yamaguchi, Kakuhiro, Horimasu, Yasushi, Miyamoto, Shintaro, Iwamoto, Hiroshi, Fujitaka, Kazunori, Hamada, Hironobu, Takahashi, Shinya, Nakashima, Ayumu, and Hattori, Noboru

Abstract

Additional file 8: S-MSCs or SF-MSCs were seeded into 24-well plates at a density of 5 × 103 cells/well. These MSCs were cultured in serum-free DMEM for 48 h. The supernatants of the culture medium were collected at 6, 12, 24, or 48 h, and the TGF-β1 concentration in the supernatants was measured using an ELISA kit. Data are expressed as concentration of TGF-β1 per each live 100,000 MSCs in the cell culture media. Data are presented as means ± SD (n = 4 per group). On the indicated hours, there was no statistically significant difference in TGF-β1 between the two MSC groups.

Published
2021
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76. Additional file 6 of Human bone marrow-derived mesenchymal stromal cells cultured in serum-free media demonstrate enhanced antifibrotic abilities via prolonged survival and robust regulatory T cell induction in murine bleomycin-induced pulmonary fibrosis

Author

Takao, Shun, Nakashima, Taku, Masuda, Takeshi, Namba, Masashi, Sakamoto, Shinjiro, Yamaguchi, Kakuhiro, Horimasu, Yasushi, Miyamoto, Shintaro, Iwamoto, Hiroshi, Fujitaka, Kazunori, Hamada, Hironobu, Takahashi, Shinya, Nakashima, Ayumu, and Hattori, Noboru

Abstract

Additional file 6: Hydroxyproline levels in the murine left lung at 14 days after BLM OA. At 4 days after BLM OA, mice were further subjected to subcutaneous (sc) or intraperitoneal (ip) administration of SF-MSCs at a dose of 1 × 105 in 100 µL of PBS. Mice without MSC administration were used as controls. Data are presented as the means ± SD (n = 5–8 per group). NS, not significant.

Published
2021
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78. Additional file 1 of Quantitative parameters of lymphocyte nuclear morphology in bronchoalveolar lavage fluid as novel biomarkers for sarcoidosis

Author

Horimasu, Yasushi, Yamaguchi, Kakuhiro, Sakamoto, Shinjiro, Masuda, Takeshi, Miyamoto, Shintaro, Nakashima, Taku, Iwamoto, Hiroshi, Fujitaka, Kazunori, Hamada, Hironobu, and Hattori, Noboru

Subjects
respiratory system
Abstract

Additional file 1: Fig. S1. Frequency distribution of BALF lymphocyte nuclear area. The dark gray bars represent the frequency distribution of the BALF lymphocyte nuclear area in sarcoidosis patients, while the light gray bars represent those in the other ILD patients. The vertical dotted line represents the sarcoidosis-diagnostic threshold of the nuclear area (428.1 μm2). Representative lymphocytes with small nuclear areas, those near the threshold value, and those with large nuclear areas are shown in the lower left panel, lower middle panel, and lower right panel, respectively. Fig. S2. Frequency distribution of BALF lymphocyte nuclear perimeters. The dark gray bars represent the frequency distribution of the BALF lymphocyte nuclear perimeters in sarcoidosis patients, while the light gray bars represent those in the other ILD patients. The vertical dotted line represents the sarcoidosis-diagnostic threshold of the nuclear perimeter (71.3 μm). Representative lymphocytes with short nuclear perimeters, those near the threshold value, and those with large nuclear perimeters are shown in the lower left panel, lower middle panel, and lower right panel, respectively. Fig. S3. Frequency distribution of BALF lymphocyte nuclear radius ratios. The dark gray bars represent the frequency distribution of the BALF lymphocyte nuclear radius ratios in sarcoidosis patients, while the light gray bars represent those in the other ILD patients. The vertical dotted line represents the sarcoidosis diagnostic threshold of the nuclear radius ratio (1.346). Representative lymphocytes with small nuclear radius ratios, those near the threshold value, and those with large nuclear radius ratios are shown in the lower left panel, lower middle panel, and lower right panel, respectively. Fig. S4. Frequency distribution of BALF lymphocyte nuclear roundness. The dark gray bars represent the frequency distribution of BALF lymphocyte nuclear roundness in sarcoidosis patients, while the light gray bars represent those in the other ILD patients. The vertical dotted line represents the sarcoidosis diagnostic threshold for nuclear roundness (1.0057). Representative lymphocytes with small nuclear roundness, those near the threshold value, and those with large nuclear roundness are shown in the lower left panel, lower middle panel, and lower right panel, respectively. Fig. S5. The four morphological parameters of BALF lymphocyte nuclei. The figures are representing the definition of area, perimeter, radius ratio and roundness of lymphocyte nucleus

Published
2021
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79. Additional file 7 of Human bone marrow-derived mesenchymal stromal cells cultured in serum-free media demonstrate enhanced antifibrotic abilities via prolonged survival and robust regulatory T cell induction in murine bleomycin-induced pulmonary fibrosis

Author

Takao, Shun, Nakashima, Taku, Masuda, Takeshi, Namba, Masashi, Sakamoto, Shinjiro, Yamaguchi, Kakuhiro, Horimasu, Yasushi, Miyamoto, Shintaro, Iwamoto, Hiroshi, Fujitaka, Kazunori, Hamada, Hironobu, Takahashi, Shinya, Nakashima, Ayumu, and Hattori, Noboru

Subjects
sense organs, eye diseases
Abstract

Additional file 7: Representative flow cytometry analysis on engrafted DiI-labeled MSCs in the murine lung. DiI-labeled SF-MSCs were injected into mice subcutaneously (sc) or intraperitoneally (ip) at a dose of 2.0 × 105 cells/mouse in 100 µL of PBS at 4 days after BLM OA. On the day after DiI-labeled SF-MSC injection, MSCs engrafted in murine lungs were measured using flow cytometry.

Published
2021
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80. Vocal cord dysfunction detected by a three-dimensional image of dynamic change in respiratory resistance in a patient with difficult-to-treat asthma: a case report.

Author

Oda, Ayaka, Otani, Toshihito, Iwamoto, Hiroshi, Nishida, Manabu, Horibe, Yuichiro, Yamaguchi, Kakuhiro, Sakamoto, Shinjiro, Horimasu, Yasushi, Masuda, Takeshi, Miyamoto, Shintaro, Nakashima, Taku, Fujitaka, Kazunori, Hamada, Hironobu, Takeno, Sachio, and Hattori, Noboru

Subjects
VOCAL cord dysfunction, THREE-dimensional imaging, ASTHMATICS, RESISTANCE to change, PULMONARY function tests, VOCAL cords
Abstract

Vocal cord dysfunction (VCD) often coexists with asthma and exacerbates respiratory symptoms. A noninvasive method could be considered beneficial for the detection and follow-up of VCD complicated by asthma. Here, we report a case of VCD complicated by asthma, highlighting the effectiveness of colored three-dimensional (3-D) imaging of respiratory impedance using a broadband frequency forced oscillation technique (MostGraph). A 74-year-old woman with difficult-to-treat asthma, in whom mepolizumab treatment was ineffective, was referred to our hospital. Stridulous sounds were loudest over the anterior neck. Pulmonary function tests' results were normal; however, a flattening of the inspiratory flow-volume curve was detected. Remarkably, prominent spikes were observed in the inspiratory phase in the colored 3-D imaging of respiratory resistance, which was superimposed on increased respiratory resistance in the expiratory phase. Flexible laryngoscopy revealed the adduction of vocal cords on inspiration. The patient was diagnosed with asthma complicated by VCD. After successful treatment of VCD by speech therapy, inspiratory spikes of respiratory resistance disappeared, and normal vocal cord movement was observed on laryngoscopy. The present case report indicates the effectiveness of forced oscillometry in evaluating dynamic changes in respiratory resistance for detecting and monitoring VCD complicated by asthma. [ABSTRACT FROM AUTHOR]

Published
2022
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82. Vocal cord dysfunction detected by a three-dimensional image of dynamic change in respiratory resistance in a patient with difficult-to-treat asthma: a case report

Author

Oda, Ayaka, primary, Otani, Toshihito, additional, Iwamoto, Hiroshi, additional, Nishida, Manabu, additional, Horibe, Yuichiro, additional, Yamaguchi, Kakuhiro, additional, Sakamoto, Shinjiro, additional, Horimasu, Yasushi, additional, Masuda, Takeshi, additional, Miyamoto, Shintaro, additional, Nakashima, Taku, additional, Fujitaka, Kazunori, additional, Hamada, Hironobu, additional, Takeno, Sachio, additional, and Hattori, Noboru, additional

Published
2021
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83. Risk factors associated with increased discontinuation rate of trimethoprim–sulfamethoxazole used as a primary prophylaxis for Pneumocystis pneumonia: A retrospective cohort study

Author

Otani, Toshihito, primary, Yamaguchi, Kakuhiro, additional, Sakamoto, Shinjiro, additional, Horimasu, Yasushi, additional, Masuda, Takeshi, additional, Miyamoto, Shintaro, additional, Nakashima, Taku, additional, Iwamoto, Hiroshi, additional, Hirata, Shintaro, additional, Fujitaka, Kazunori, additional, Hamada, Hironobu, additional, Sugiyama, Eiji, additional, and Hattori, Noboru, additional

Published
2021
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84. Analysis of microRNA Expression in Liquid-Based Cytology Samples May Be Useful for Primary Lung Cancer Diagnosis

Author

Araki, Yusuke, primary, Arihiro, Koji, additional, Yamaguchi, Kakuhiro, additional, Sakamoto, Shinjiro, additional, Horimasu, Yasushi, additional, Masuda, Takeshi, additional, Miyamoto, Shintaro, additional, Nakashima, Taku, additional, Iwamoto, Hiroshi, additional, Fujitaka, Kazunori, additional, Hamada, Hironobu, additional, and Hattori, Noboru, additional

Published
2021
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85. Autoantibody Positivity Is a Risk Factor for Chemotherapy-induced Exacerbation of Interstitial Pneumonia in Lung Cancer

Author

ITO, NORIAKI, primary, MASUDA, TAKESHI, additional, NAKASHIMA, TAKU, additional, NAKAO, SATOSHI, additional, YAMAGUCHI, KAKUHIRO, additional, SAKAMOTO, SHINJIRO, additional, HORIMASU, YASUSHI, additional, MIYAMOTO, SHINTARO, additional, IWAMOTO, HIROSHI, additional, FUJITAKA, KAZUNORI, additional, HAMADA, HIRONOBU, additional, and HATTORI, NOBORU, additional

Published
2021
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86. D-dimer can be a diagnostic marker for cisplatin-related aortic thrombosis

Author

Matsumoto, Yu, primary, Horimasu, Yasushi, additional, Yamaguchi, Kakuhiro, additional, Sakamoto, Shinjiro, additional, Masuda, Takeshi, additional, Nakashima, Taku, additional, Miyamoto, Shintaro, additional, Iwamoto, Hiroshi, additional, Fujitaka, Kazunori, additional, Hamada, Hironobu, additional, and Hattori, Noboru, additional

Published
2021
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87. A machine-learning based approach to quantify fine crackles in the diagnosis of interstitial pneumonia

Author

Horimasu, Yasushi, primary, Ohshimo, Shinichiro, additional, Yamaguchi, Kakuhiro, additional, Sakamoto, Shinjiro, additional, Masuda, Takeshi, additional, Nakashima, Taku, additional, Miyamoto, Shintaro, additional, Iwamoto, Hiroshi, additional, Fujitaka, Kazunori, additional, Hamada, Hironobu, additional, Sadamori, Takuma, additional, Shime, Nobuaki, additional, and Hattori, Noboru, additional

Published
2021
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88. Alectinib-induced Immune Hemolytic Anemia in a Patient with Lung Adenocarcinoma

Author

Okumoto, Joe, primary, Sakamoto, Shinjiro, additional, Masuda, Takeshi, additional, Yamaguchi, Kakuhiro, additional, Horimasu, Yasushi, additional, Miyamoto, Shintaro, additional, Nakashima, Taku, additional, Iwamoto, Hiroshi, additional, Fukushima, Noriyasu, additional, Fujitaka, Kazunori, additional, Hamada, Hironobu, additional, and Hattori, Noboru, additional

Published
2021
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92. Additional file 1 of Reduced endogenous secretory RAGE in blood and bronchoalveolar lavage fluid is associated with poor prognosis in idiopathic pulmonary fibrosis

Author

Kakuhiro Yamaguchi, Iwamoto, Hiroshi, Mazur, Witold, Miura, Shinichiro, Shinjiro Sakamoto, Horimasu, Yasushi, Masuda, Takeshi, Miyamoto, Shintaro, Nakashima, Taku, Ohshimo, Shinichiro, Fujitaka, Kazunori, Hamada, Hironobu, and Hattori, Noboru

Subjects
Data_FILES
Abstract

Additional file 1.

Published
2020
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93. Two Cases of Cranial Nerve Metastasis Treated with Radiotherapy and Chemotherapy in Patients with Lung Adenocarcinoma

Author

Kobayashi, Erika, primary, Masuda, Takeshi, additional, Nakao, Satoshi, additional, Yamaguchi, Kakuhiro, additional, Sakamoto, Shinjiro, additional, Horimasu, Yasushi, additional, Miyamoto, Shintaro, additional, Nakashima, Taku, additional, Iwamoto, Hiroshi, additional, Fujitaka, Kazunori, additional, Hamada, Hironobu, additional, and Hattori, Noboru, additional

Published
2020
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94. Association of Preexisting Interstitial Lung Abnormalities With Immune Checkpoint Inhibitor–Induced Interstitial Lung Disease Among Patients With Nonlung Cancers

Author

Shimoji, Kiyofumi, primary, Masuda, Takeshi, additional, Yamaguchi, Kakuhiro, additional, Sakamoto, Shinjiro, additional, Horimasu, Yasushi, additional, Nakashima, Taku, additional, Miyamoto, Shintaro, additional, Iwamoto, Hiroshi, additional, Fujitaka, Kazunori, additional, Hamada, Hironobu, additional, Takeno, Sachio, additional, Hide, Michihiro, additional, Teishima, Jun, additional, Ohdan, Hideki, additional, and Hattori, Noboru, additional

Published
2020
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95. Clinical significance of BIM deletion polymorphism in chemoradiotherapy for non‐small cell lung cancer

Author

Wakabayashi, Yu, primary, Masuda, Takeshi, additional, Fujitaka, Kazunori, additional, Nakashima, Taku, additional, Okumoto, Joe, additional, Shimoji, Kiyofumi, additional, Nishimura, Yoshifumi, additional, Yamaguchi, Kakuhiro, additional, Sakamoto, Shinjiro, additional, Horimasu, Yasushi, additional, Miyamoto, Shintaro, additional, Iwamoto, Hiroshi, additional, Ohshimo, Shinichiro, additional, Hamada, Hironobu, additional, and Hattori, Noboru, additional

Published
2020
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96. Concomitant emphysema might increase the false-negative rate of urinary antigen tests in patients with pneumococcal pneumonia: results from a retrospective study

Author

Kobayashi, Erika, primary, Yamaguchi, Kakuhiro, additional, Nagaoka, Rie, additional, Sakamoto, Shinjiro, additional, Horimasu, Yasushi, additional, Masuda, Takeshi, additional, Miyamoto, Shintaro, additional, Nakashima, Taku, additional, Iwamoto, Hiroshi, additional, Fujitaka, Kazunori, additional, Yokozaki, Michiya, additional, Ohge, Hiroki, additional, Hamada, Hironobu, additional, and Hattori, Noboru, additional

Published
2020
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100. Coexisting TIF1γ-positive Primary Pulmonary Lymphoepithelioma-like Carcinoma and Anti-TIF1γ Antibody-positive Dermatomyositis

Author

Nakanishi, Yu, primary, Yamaguchi, Kakuhiro, additional, Yoshida, Yusuke, additional, Sakamoto, Shinjiro, additional, Horimasu, Yasushi, additional, Masuda, Takeshi, additional, Nakashima, Taku, additional, Miyamoto, Shintarou, additional, Iwamoto, Hiroshi, additional, Hirata, Shintaro, additional, Fujitaka, Kazunori, additional, Hamada, Hironobu, additional, Sugiyama, Eiji, additional, and Hattori, Noboru, additional

Published
2020
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