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55. Bir Olgu Nedeniyle Poland Sendromu.

Author

Hacievliyagi, Süleyman Savaş, Gülbaş, Gazi, Mutlu, Levent Cem, Yetkin, Özkan, Ulutaş, Hakki, and Günen, Hakan

Published
2006

56. Sarkoidoz: On Altı Yaşında Bir Vaka Sunumu

Author

NALBANTOĞLU, Burçin, MUTLU, Levent Cem, UYSALOL, Metin, and KARASU, Erkut

Subjects
Sarkoidoz,çocuk,granülom, Sarcoidosis,child,granuloma
Abstract

Sarkoidoz, etiyolojisi bilinmeyen kronik multisistematik granülomatoz bir hastalıktır. Granülomlar, enfeksiyoz ya da organik ajanlara bağlı bir etiyolojiyi düşündürmekle beraber, nedeni hâlâ belli olmayan bir hastalıktır. On altı yaşında kız hasta, 4 aydır devam eden öksürük, halsizlik, bacaklarda morluklar yakınması ile başvurdu. Hastanın muayenesinde bacaklarında gözlenen eritema nodozum benzeri mor renkli hafif ağrılı en büyüğü 5 cm olan lezyon- lar dışında patolojik bulgu yoktu. Laboratuvar bulguların- da sedim 60/1 saat, CRP 15,66 mg/L olarak bulundu. Anjiotensin dönüştürücü enzim düzeyi yüksek olarak bulun- du. Toraks HRCT’de multipl mediastinal lenfadenopatiler, sağ orta ve altta mikronodüler parankimal infiltrasyonlar saptandı. Bronkoskopide lenfadenopati dışında patolojik bulgu izlenmedi, biyopside granülomatoz lezyonlar görül- dü. Bu bulgularla sarkoidoz düşünülen hasta klinik bulgu- ların çok ağır olmaması üzerine tedavisiz izleme alındı. Sarkoidoz, çocukluk çağında ender görülen bir hastalıktır. Spontan düzelme görülebildiği gibi, kronikleşebilmektedir. Hastaların muayene ve solunum fonksiyon testleri ile takibi gerekmektedir. Kliniğin ağırlığına göre steroid veya metot- rexat ile tedavi edilebilir, ancak sonuçlar tartışmalıdır. Ender görülen bir durum olduğu için bir vaka nedeniyle sarkoidozu vurgulamak ve literatürü derlemek istedik, Sarcoidosis is a multisystemic, granulomatous disease with an unknown etiology. Although granulomas suggest an eti- ology related to infectious, and organic agents, their etiolo- gies are still unknown. A 16 year-old girl referred with complaints of cough, malaise, and painful lesions on legs lasting for 4 months. On physical examination, no patholo- gical sign was observed, except an erythema nodosum-like purple lesion, the largest one being 5 cm in diameter was detected on the tibial region. Erythrocyte sedimentation rate was 60/1 hour and CRP 15.66 mg/L. Angiotension conver- ting enzyme level was elevated. High resolution thoracal CT results were reported as multiple mediastinal lymphadeno- paties and micronodular parenchymal infiltrations at right middle and lower lobes. In biopsy, taken during bronchos- copy, granulamatous lesions were observed. Patient was suggestively diagnosed as sarcoidosis with these findings and followed up without treatment because of relatively lesser severity of these findings. Sarcoidosis is a rare disea- se of childhood, and can spontaneously resolve or become chronic. Follow-up of the patients with physical examinati- on and respiratory function tests are necessary. Steroids or methotrexate can be used for the treatment according to the clinical severity of the disease, but results are controversial. Since it a rarely seen condition, we want to emphasize the importance of sarcoidosis and review the literature

58. Assesment of palliative care in lung cancer in Turkey (ASPECT study)

Author

Makbule Ozlem Akbay, Serdar Berk, Hüseyin Can, Zehra Yasar, Melike Ozcelik, Aysegul Senturk, Serap Argun Baris, Hidir Esme, Fahrettin Talay, Hatice Selimoglu Sen, Talat Kilic, Mehmet Yavsan, Serhat Erol, Arife Ulas, Perran Fulden Yumuk, Hulya Gunbatar, Yavuz Selim Intepe, Ayse Bahadir, Ufuk Yilmaz, Ozlem Oruc, Mehmet Besiroglu, Gamze Kirkil, Tevfik Özlü, Sibel Ayik, Levent Cem Mutlu, Yurdanur Erdogan, Ümran Toru, Murat Acat, Ilknur Basyigit, Dursun Tatar, Buğra Kerget, Sibel Arinc, Leyla Saglam, Yılmaz Bülbül, Neslihan Özçelik, Gulfidan Cakmak, Ahmet Emin Erbaycu, Muharrem Erol, Berna Akıncı Özyürek, Selvi Asker, Turgut Teke, Sibel Özkurt, [Bulbul, Yilmaz -- Ozlu, Tevfik -- Ozcelik, Neslihan] Karadeniz Tech Univ, Sch Med, Chest Dis, Trabzon, Turkey -- [Arinc, Sibel -- Akbay, Makbule Ozlem -- Oruc, Ozlem] Sureyyapasa Pulm Dis & Thorac Surg Educ & Res Hos, Chest Dis, Istanbul, Turkey -- [Ozyurek, Berna A. -- Erdogan, Yurdanur] Ataturk Pulm Dis & Thorac Surg Educ & Res Hosp, Chest Dis, Ankara, Turkey -- [Gunbatar, Hulya -- Asker, Selvi] Yuzuncu Yil Univ, Sch Med, Chest Dis, Van, Turkey -- [Senturk, Aysegul -- Ulas, Arife] Ataturk Educ & Res Hosp, Chest Dis, Ankara, Turkey -- [Bahadir, Ayse] Yedikule Pulm Dis & Thorac Surg Educ & Res Hosp, Chest Dis, Istanbul, Turkey -- [Ozcelik, Melike] Kartal Educ & Res Hosp, Med Oncol, Istanbul, Turkey -- [Yilmaz, Ufuk -- Tatar, Dursun -- Erol, Serhat -- Erbaycu, Ahmet Emin] Dr Suat Seren Pulm Dis & Thorac Surg Educ & Res H, Chest Dis, Izmir, Turkey -- [Saglam, Leyla -- Kerget, Bugra] Ataturk Univ, Sch Med, Chest Dis, Erzurum, Turkey -- [Kilic, Talat] Inonu Univ, Sch Med, Chest Dis, Malatya, Turkey -- [Kirkil, Gamze] Firat Univ, Sch Med, Chest Dis, Elazig, Turkey -- [Baris, Serap Argun -- Basyigit, Ilknur] Kocaeli Univ, Sch Med, Chest Dis, Kocaeli, Turkey -- [Yavsan, Mehmet -- Teke, Turgut] Necmettin Erbakan Univ, Meram Sch Med, Chest Dis, Konya, Turkey -- [Sen, Hatice Selimoglu] Dicle Univ, Sch Med, Chest Dis, Diyarbakir, Turkey -- [Berk, Serdar] Cumhuriyet Univ, Sch Med, Chest Dis, Sivas, Turkey -- [Acat, Murat] Karabuk Univ, Sch Med, Chest Dis, Zonguldak, Turkey -- [Cakmak, Gulfidan] Haseki Educ & Res Hosp, Chest Dis, Istanbul, Turkey -- [Yumuk, Perran Fulden -- Besiroglu, Mehmet] Marmara Univ, Sch Med, Med Oncol, Istanbul, Turkey -- [Intepe, Yavuz Selim] Bozok Univ, Sch Med, Chest Dis, Yozgat, Turkey -- [Toru, Umran] Dumlupinar Univ, Sch Med, Chest Dis, Kutahya, Turkey -- [Ayik, Sibel O. -- Can, Huseyin] Katip Celebi Univ, Sch Med, Chest Dis, Izmir, Turkey -- [Ozkurt, Sibel] Pamukkale Univ, Sch Med, Chest Dis, Denizli, Turkey -- [Mutlu, Levent Cem] Namik Kemal Univ, Sch Med, Chest Dis, Tekirdag, Turkey -- [Yasar, Zehra Asuk -- Talay, Fahrettin] Abant Izzet Baysal Univ, Sch Med, Chest Dis, Bolu, Turkey -- [Esme, Hidir] Konya Educ & Res Hosp, Thorac Surg, Konya, Turkey -- [Erol, Muharrem] Uludag Univ, Sch Med, Thorac Surg, Bursa, Turkey, Bulbul, Yilmaz -- 0000-0002-8488-3650, and Zonguldak Bülent Ecevit Üniversitesi

Subjects
medicine.medical_specialty, Lung cancer / Oncology, Palliative care, Neoplastic diseases, Nausea, business.industry, Analgesic, macromolecular substances, Disease, medicine.disease, Enteral administration, Internal medicine, Anesthesia, medicine, Anxiety, medicine.symptom, business, Lung cancer, Depression (differential diagnoses)
Abstract

WOS: 000451979407036, …

Published
2015

59. General characteristics and therapeutic options in lung cancer in Turkey

Author

Turgut Teke, Muharrem Erol, Berna Akıncı Özyürek, Ilknur Basyigit, Dursun Tatar, Melike Ozcelik, Hatice Selimoglu Sen, Hidir Esme, Mehmet Yavsan, Perran Fulden Yumuk, Serhat Erol, Leyla Saglam, Neslihan Özçelik, Gulfidan Cakmak, Serap Argun Baris, Ahmet Emin Erbaycu, Sibel Arinc, Arife Ulas, Tevfik Özlü, Gamze Kirkil, Mehmet Besiroglu, Yurdanur Erdogan, Ufuk Yilmaz, Buğra Kerget, Sibel Özkurt, Zehra Yasar, Makbule Ozlem Akbay, Serdar Berk, Talat Kilic, Hulya Gunbatar, Hüseyin Can, Aysegul Senturk, Ozlem Oruc, Fahrettin Talay, Levent Cem Mutlu, Yılmaz Bülbül, Ümran Toru, Ayse Bahadir, Selvi Asker, Yavuz Selim Intepe, Sibel Ayik, Murat Acat, Zonguldak Bülent Ecevit Üniversitesi, [Ozlu, Tevfik -- Bulbul, Yilmaz -- Ozcelik, Neslihan] Karadeniz Tech Univ, Chest Dis, Sch Med, Trabzon, Turkey -- [Arinc, Sibel -- Akbay, Makbule Ozlem -- Oruc, Ozlem] Sureyyapasa Pulm Dis & Thorac Surg Educ & Res Hos, Chest Dis, Istanbul, Turkey -- [Ozyurek, Berna A. -- Erdogan, Yurdanur] Ataturk Pulm Dis & Thorac Surg Educ & Res Hosp, Chest Dis, Ankara, Turkey -- [Gunbatar, Hulya -- Asker, Selvi] Yuzuncu Yil Univ, Chest Dis, Sch Med, Van, Turkey -- [Senturk, Aysegul -- Ulas, Arife] Ataturk Educ & Res Hosp, Chest Dis, Ankara, Turkey -- [Bahadir, Ayse] Yedikule Pulm Dis & Thorac Surg Educ & Res Hosp, Chest Dis, Istanbul, Turkey -- [Ozcelik, Melike] Kartal Educ & Res Hosp, Med Oncol, Istanbul, Turkey -- [Yilmaz, Ufuk -- Tatar, Dursun -- Erol, Serhat -- Erbaycu, Ahmet Emin] Dr Suat Seren Pulm Dis & Thorac Surg Educ & Res H, Chest Dis, Izmir, Turkey -- [Saglam, Leyla -- Kerget, Bugra] Ataturk Univ, Chest Dis, Sch Med, Erzurum, Turkey -- [Kilic, Talat] Inonu Univ, Chest Dis, Sch Med, Malatya, Turkey -- [Kirkil, Gamze] Firat Univ, Chest Dis, Sch Med, Elazig, Turkey -- [Baris, Serap Argun -- Basyigit, Ilknur] Kocaeli Univ, Chest Dis, Sch Med, Kocaeli, Turkey -- [Yavsan, Mehmet -- Teke, Turgut] Necmettin Erbakan Univ, Chest Dis, Meram Sch Med, Konya, Turkey -- [Sen, Hatice Selimoglu] Dicle Univ, Chest Dis, Sch Med, Diyarbakir, Turkey -- [Berk, Serdar] Cumhuriyet Univ, Chest Dis, Sch Med, Sivas, Turkey -- [Acat, Murat] Karabuk Univ, Chest Dis, Sch Med, Zonguldak, Turkey -- [Cakmak, Gulfidan] Haseki Educ & Res Hosp, Chest Dis, Istanbul, Turkey -- [Yumuk, Perran Fulden -- Besiroglu, Mehmet] Marmara Univ, Med Oncol, Sch Med, Istanbul, Turkey -- [Intepe, Yavuz Selim] Bozok Univ, Chest Dis, Sch Med, Yozgat, Turkey -- [Toru, Umran] Dumlupinar Univ, Chest Dis, Sch Med, Kutahya, Turkey -- [Ayik, Sibel O. -- Can, Huseyin] Katip Celebi Univ, Chest Dis, Sch Med, Izmir, Turkey -- [Ozkurt, Sibel] Pamukkale Univ, Chest Dis, Sch Med, Denizli, Turkey -- [Mutlu, Levent Cem] Namik Kemal Univ, Chest Dis, Sch Med, Tekirdag, Turkey -- [Yasar, Zehra Asuk -- Talay, Fahrettin] Abant Izzet Baysal Univ, Chest Dis, Sch Med, Bolu, Turkey -- [Esme, Hidir] Konya Educ & Res Hosp, Thorac Surg, Konya, Turkey -- [Erol, Muharrem] Uludag Univ, Thorac Surg, Sch Med, Bursa, Turkey, and Bulbul, Yilmaz -- 0000-0002-8488-3650

Subjects
Oncology, medicine.medical_specialty, Chemotherapy, Lung cancer / Oncology, Neoplastic diseases, business.industry, medicine.medical_treatment, Cancer, medicine.disease, Gemcitabine, Metastasis, Radiation therapy, Mediastinal tumour, Pemetrexed, Internal medicine, medicine, Lung cancer, business, Etoposide, medicine.drug
Abstract

WOS: 000451979406201, …

Published
2015

60. Demographic and Asthma-Related Characteristics of Asthmatics Using Pressurized Metered Dose Inhalers and Dry Powder Inhalers.

Author

Aksu K, Vural Solak GT, Mutlu LC, Mutlu P, Vayısoğlu Şahin G, Erdem Türe E, Yormaz B, Çapraz A, Coşkun Beyan A, Solak Y, and Aksu F

Abstract

Background: Asthma controller medications can be delivered via pressurized metered dose inhaler (pMDI) or dry powder inhaler (DPI) devices. Objective: This study aimed to evaluate the frequency of exacerbations and satisfaction rate with device use in asthmatics using pMDIs or DPIs. Methods: A multicenter, cross-sectional study was conducted in adults who used pMDIs or DPIs with correct inhaler technique and good adherence for asthma treatment. Demographic and asthma-related characteristics of the subjects and data regarding device satisfaction were collected through a face-to-face interview in the outpatient clinic. Rates of pMDI and DPI users and the data were compared between the two groups. Results: The study included 338 patients (mean age: 48.6 ± 14.5 years, 253 [74.9%] women). Among participants, 96 (28.4%) were using pMDI and 242 (71.6%) were using DPI. The age of patients using pMDI were significantly lower compared with DPI users. No significant difference was observed in terms of device satisfaction and clinical outcomes of asthma between pMDI and DPI users with good inhaler technique and good adherence. Conclusion: More asthmatics use DPIs, however, pMDIs are used in younger asthmatic patients. No significant difference in terms of device satisfaction and clinical outcomes of asthma was observed between pMDI and DPI users.

Published
2024
Full Text
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61. Is Mean Platelet Volume a Predictive Marker for the Development of Thrombosis in Patients with COVID-19 Infection?

Author

Erdem I, Ardic E, Yildirim I, Kavak C, Mutlu LC, Erdal B, and Ozkan G

Subjects
Humans, Male, Female, Middle Aged, Aged, Platelet Count, Adult, Predictive Value of Tests, Biomarkers blood, Blood Platelets metabolism, Platelet Activation, Prognosis, Aged, 80 and over, SARS-CoV-2, COVID-19 complications, COVID-19 blood, COVID-19 diagnosis, Mean Platelet Volume, Thrombosis blood, Thrombosis etiology, Thrombosis diagnosis
Abstract

Mean platelet volume (MPV) can provide important information about the course and prognosis of many diseases. MPV is an early indicator of platelet activation, which has an important role in the pathogenesis of thrombosis. In this study, we aimed to investigate whether MPV was a predictive marker for the development of thrombosis in hospitalized patients with COVID-19 infection. Fifty-seven patients whose courses were followed after the diagnosis of COVID-19 infection using a polymerase chain reaction test during the pandemic were included in the study. Our results demonstrated that there was a negative correlation between platelet count and MPV (r=0.470, p≤ 0.01), and there was a positive correlation between Platelet Distribution Width (PDW) and MPV (r=0,933, p≤ 0.01), but no significant correlation was found between the other variables and MPV.

Published
2024
Full Text
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62. [The concordance of manuel (visual) scoring and automatic analysis in sleep staging].

Author

Oztürk O, Mutlu LC, Sağcan G, Deniz Y, and Cuhadaroğlu C

Subjects
Adolescent, Adult, Aged, Female, Humans, Male, Middle Aged, Sensitivity and Specificity, Sleep physiology, Wakefulness physiology, Young Adult, Electronic Data Processing, Observation, Polysomnography, Sleep Stages physiology, Sleep Wake Disorders diagnosis
Abstract

Full night polysomnography (PSG) remains the gold standard diagnostic test for the evaluation of sleep and the detection of sleep disorders. The computer-assisted scoring methods have been developed to accelerate the scoring. It is said that there was a concordance up to 80% between these scoring softwares and manual scoring. According to our experiences, it is not matched with this belief. In this study, we intend to examine whether the results of automatic analysis match with manual (visual) evaluation. The PSG records of 30 cases with a diagnosis of obstructive sleep apnea syndrome (OSAS) are chosen randomly. We compare the results of automatic analysis with the results of two scorers who have a concordance of 80-95% and at least 1000 PSG scoring experiences. We evaluated 21.060 epochs of 18 men with 48.83 + or - 13.51 ages, and 12 women with 44.56 + or - 14.28 ages. In automatic analysis; total sleep time (p= 0.003) and sleep efficiency (p= 0.004) were low. AHI (p= 0.802) and ODI (p= 0.193) values were high. The epochs scored differently were 8819 epochs (41.88%). The stage I (88.43%) scored mostly different, was allocated to be awake (572 epochs). Stage II and stage IV were scored as stage III in 2276 and 983 epochs respectively. REM epochs were allocated to stage II (574 epochs). The differences in recording times and sleep architecture of PSG tests which examed by automatic analysis will affect all other parameters. Thus, we believe that it will make mistakes in the diagnosis and treatment of sleep disorders.

Published
2009

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