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52. Eisenmenger Syndrome

Author

Arvanitaki, Alexandra, primary, Gatzoulis, Michael A., additional, Opotowsky, Alexander R., additional, Khairy, Paul, additional, Dimopoulos, Konstantinos, additional, Diller, Gerhard-Paul, additional, Giannakoulas, George, additional, Brida, Margarita, additional, Griselli, Massimo, additional, Grünig, Ekkehard, additional, Montanaro, Claudia, additional, Alexander, Peter David, additional, Ameduri, Rebecca, additional, Mulder, Barbara J.M., additional, and D’Alto, Michele, additional

Published
2022
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66. Baffle complications in adults after atrial switch for transposition of the great arteries

Author

Woudstra, Odilia I., primary, Alban, Fabienne T.E., additional, Bijvoet, Geertruida P., additional, de Bruin-Bon, Rianne H.A.C.M., additional, Planken, R. Nils, additional, Leiner, Tim, additional, Boekholdt, S. Matthijs, additional, Warmerdam, Evangeline G., additional, Sieswerda, Gertjan T., additional, Mulder, Barbara J.M., additional, Bouma, Berto J., additional, and Meijboom, Folkert J., additional

Published
2021
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74. 2020 ESC Guidelines for the management of adult congenital heart disease

Author

Baumgartner, Helmut, primary, De Backer, Julie, additional, Babu-Narayan, Sonya V., additional, Budts, Werner, additional, Chessa, Massimo, additional, Diller, Gerhard-Paul, additional, Lung, Bernard, additional, Kluin, Jolanda, additional, Lang, Irene M., additional, Meijboom, Folkert, additional, Moons, Philip, additional, Mulder, Barbara J.M., additional, Oechslin, Erwin, additional, Roos-Hesselink, Jolien W., additional, Schwerzmann, Markus, additional, Sondergaard, Lars, additional, and Zeppenfeld, Katja, additional

Published
2021
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75. 2020 ESC Guidelines for the management of adult congenital heart disease

Author

Baumgartner, Helmut, de Backer, Julie, Babu-Narayan, Sonya V., Budts, Werner, Chessa, Massimo, Diller, Gerhard Paul, Iung, Bernard, Kluin, Jolanda, Lang, Irene M., Meijboom, Folkert, Moons, Philip, Mulder, Barbara J.M., Oechslin, Erwin, Roos-Hesselink, Jolien W., Schwerzmann, Markus, Sondergaard, Lars, Zeppenfeld, Katja, Windecker, Stephan, Aboyans, Victor, Baigent, Colin, Collet, Jean Philippe, Dean, Veronica, Delgado, Victoria, Fitzsimons, Donna, Gale, Chris P., Grobbee, Diederick E., Halvorsen, Sigrun, Hindricks, Gerhard, Jüni, Peter, Katus, Hugo A., Landmesser, Ulf, Leclercq, Christophe, Lettino, Maddalena, Lewis, Basil S., Merkely, Béla, Mueller, Christian, Petersen, Steffen E., Petronio, Anna Sonia, Richter, Dimitrios J., Roffi, Marco, Shlyakhto, Evgeny, Simpson, Iain A., Sousa-Uva, Miguel, Touyz, Rhian M., Baumgartner, Helmut, de Backer, Julie, Babu-Narayan, Sonya V., Budts, Werner, Chessa, Massimo, Diller, Gerhard Paul, Iung, Bernard, Kluin, Jolanda, Lang, Irene M., Meijboom, Folkert, Moons, Philip, Mulder, Barbara J.M., Oechslin, Erwin, Roos-Hesselink, Jolien W., Schwerzmann, Markus, Sondergaard, Lars, Zeppenfeld, Katja, Windecker, Stephan, Aboyans, Victor, Baigent, Colin, Collet, Jean Philippe, Dean, Veronica, Delgado, Victoria, Fitzsimons, Donna, Gale, Chris P., Grobbee, Diederick E., Halvorsen, Sigrun, Hindricks, Gerhard, Jüni, Peter, Katus, Hugo A., Landmesser, Ulf, Leclercq, Christophe, Lettino, Maddalena, Lewis, Basil S., Merkely, Béla, Mueller, Christian, Petersen, Steffen E., Petronio, Anna Sonia, Richter, Dimitrios J., Roffi, Marco, Shlyakhto, Evgeny, Simpson, Iain A., Sousa-Uva, Miguel, and Touyz, Rhian M.

Published
2021

76. Patient information portal for congenital aortic and pulmonary valve disease:A stepped-wedge cluster randomised trial

Author

Etnel, Jonathan R.G., Bons, Lidia R., De Heer, Frederiek, Robbers-Visser, Daniëlle, Van Beynum, Ingrid M., Straver, Bart, Jongbloed, Monique R.M., Kiès, Philippine, Slieker, Martijn G., Van Dijk, Arie P.J., Kluin, Jolanda, Bertels, Robin A., Utens, Elisabeth M.W.J., The, Regina, Van Galen, Eugene, Mulder, Barbara J.M., Blom, Nico A., Hazekamp, Mark G., Roos-Hesselink, Jolien W., Helbing, Willem A., Bogers, Ad J.J.C., Takkenberg, Johanna J.M., Etnel, Jonathan R.G., Bons, Lidia R., De Heer, Frederiek, Robbers-Visser, Daniëlle, Van Beynum, Ingrid M., Straver, Bart, Jongbloed, Monique R.M., Kiès, Philippine, Slieker, Martijn G., Van Dijk, Arie P.J., Kluin, Jolanda, Bertels, Robin A., Utens, Elisabeth M.W.J., The, Regina, Van Galen, Eugene, Mulder, Barbara J.M., Blom, Nico A., Hazekamp, Mark G., Roos-Hesselink, Jolien W., Helbing, Willem A., Bogers, Ad J.J.C., and Takkenberg, Johanna J.M.

Abstract

Background In response to an increased need for patient information in congenital heart disease, we previously developed an online, evidence-based information portal for patients with congenital aortic and pulmonary valve disease. To assess its effectiveness, a stepped-wedge cluster randomised trial was conducted. Methods Adult patients and caregivers of paediatric patients with congenital aortic and/or pulmonary valve disease and/or tetralogy of Fallot who visited the outpatient clinic at any of the four participating centres in the Netherlands between 1 March 2016-1 July 2017 were prospectively included. The intervention (information portal) was introduced in the outpatient clinic according to a stepped-wedge randomised design. One month after outpatient clinic visit, each participant completed a questionnaire on disease-specific knowledge, anxiety, depression, mental quality of life, involvement and opinion/attitude concerning patient information and involvement. Results 343 participants were included (221 control, 122 intervention). Cardiac diagnosis (p=0.873), educational level (p=0.153) and sex (p=0.603) were comparable between the two groups. All outcomes were comparable between groups in the intention-to-treat analyses. However, only 51.6% of subjects in the intervention group (n=63) reported actually visiting the portal. Among these subjects (as-treated), disease-specific knowledge (p=0.041) and mental health (p=0.039) were significantly better than in control subjects, while other baseline and outcome variables were comparable. Conclusion Even after being invited by their cardiologists, only half of the participants actually visited the information portal. Only in those participants that actually visited the portal, knowledge of disease and mental health were significantly better. This underlines the importance of effective implementation of online evidence-based patient information portals in clinical practice.

Published
2021

77. Cardiovascular morbidity and mortality in adult patients with repaired aortic coarctation

Author

Meijs, Timion A., Minderhoud, Savine C.S., Muller, Steven A., de Winter, Robbert J., Mulder, Barbara J.M., van Melle, Joost P., Hoendermis, Elke S., van Dijk, Arie P.J., Zuithoff, Nicolaas P.A., Krings, Gregor J., Doevendans, Pieter A., Witsenburg, Maarten, Roos-Hesselink, Jolien W., van den Bosch, Annemien E., Bouma, Berto J., Voskuil, Michiel, Meijs, Timion A., Minderhoud, Savine C.S., Muller, Steven A., de Winter, Robbert J., Mulder, Barbara J.M., van Melle, Joost P., Hoendermis, Elke S., van Dijk, Arie P.J., Zuithoff, Nicolaas P.A., Krings, Gregor J., Doevendans, Pieter A., Witsenburg, Maarten, Roos-Hesselink, Jolien W., van den Bosch, Annemien E., Bouma, Berto J., and Voskuil, Michiel

Abstract

BACKGROUND: The long-term burden of cardiovascular disease after repair of coarctation of the aorta (CoA) has not been eluci-dated. We aimed to determine the incidence of and risk factors for cardiovascular events in adult patients with repaired CoA. Additionally, mortality rates were compared between adults with repaired CoA and the general population. METHODS AND RESULTS: Using the Dutch Congenital Corvitia (CONCOR) registry, patients aged ≥16 years with previous surgical or transcatheter CoA repair from 5 tertiary referral centers were included. Cardiovascular events were recorded, comprising coronary artery disease, stroke/transient ischemic attack, aortic complications, arrhythmias, heart failure hospitalizations, en-docarditis, and cardiovascular death. In total, 920 patients (median age, 24 years [range 16–74 years]) were included. After a mean follow-up of 9.3±5.1 years, 191 patients (21%) experienced at least 1 cardiovascular event. A total of 270 cardiovascular events occurred, of which aortic complications and arrhythmias were most frequent. Older age at initial CoA repair (hazard ratio [HR], 1.017; 95% CI, 1.000–1.033 [P=0.048]) and elevated left ventricular mass index (HR, 1.009; 95% CI, 1.005–1.013 [P<0.001]) were independently associated with an increased risk of cardiovascular events. The mortality rate was 3.3 times higher than expected based on an age-and sex-matched cohort from the Dutch general population (standardized mortality ratio, 3.3; 95% CI, 2.3– 4.4 [P<0.001]). CONCLUSIONS: This large, prospective cohort of adults with repaired CoA showed a high burden of cardiovascular events, particularly aortic complications and arrhythmias, during long-term follow-up. Older age at initial CoA repair and elevated left ventricular mass index were independent risk factors for the occurrence of cardiovascular events. Mortality was 3.3-fold higher compared with the general population. These results advocate stringent follow-up after CoA repair and

Published
2021

78. Patient information portal for congenital aortic and pulmonary valve disease: A stepped-wedge cluster randomised trial

Author

Perfusie, Etnel, Jonathan R.G., Bons, Lidia R., De Heer, Frederiek, Robbers-Visser, Daniëlle, Van Beynum, Ingrid M., Straver, Bart, Jongbloed, Monique R.M., Kiès, Philippine, Slieker, Martijn G., Van Dijk, Arie P.J., Kluin, Jolanda, Bertels, Robin A., Utens, Elisabeth M.W.J., The, Regina, Van Galen, Eugene, Mulder, Barbara J.M., Blom, Nico A., Hazekamp, Mark G., Roos-Hesselink, Jolien W., Helbing, Willem A., Bogers, Ad J.J.C., Takkenberg, Johanna J.M., Perfusie, Etnel, Jonathan R.G., Bons, Lidia R., De Heer, Frederiek, Robbers-Visser, Daniëlle, Van Beynum, Ingrid M., Straver, Bart, Jongbloed, Monique R.M., Kiès, Philippine, Slieker, Martijn G., Van Dijk, Arie P.J., Kluin, Jolanda, Bertels, Robin A., Utens, Elisabeth M.W.J., The, Regina, Van Galen, Eugene, Mulder, Barbara J.M., Blom, Nico A., Hazekamp, Mark G., Roos-Hesselink, Jolien W., Helbing, Willem A., Bogers, Ad J.J.C., and Takkenberg, Johanna J.M.

Published
2021

79. Clinical course long after atrial switch: A novel risk score for major clinical events

Author

Team Onderzoek, Team Medisch, Regenerative Medicine and Stem Cells, Circulatory Health, Cardiologie, Woudstra, Odilia I., Zandstra, Tjitske E., Vogel, Rosanne F., van Dijk, Arie P.J., Vliegen, Hubert W., Kiès, Philippine, Jongbloed, Monique R.M., Egorova, Anastasia D., Doevendans, Pieter A.F.M., Konings, Thelma C., Mulder, Barbara J.M., Tanck, Michael W.T., Meijboom, Folkert J., Bouma, Berto J., Team Onderzoek, Team Medisch, Regenerative Medicine and Stem Cells, Circulatory Health, Cardiologie, Woudstra, Odilia I., Zandstra, Tjitske E., Vogel, Rosanne F., van Dijk, Arie P.J., Vliegen, Hubert W., Kiès, Philippine, Jongbloed, Monique R.M., Egorova, Anastasia D., Doevendans, Pieter A.F.M., Konings, Thelma C., Mulder, Barbara J.M., Tanck, Michael W.T., Meijboom, Folkert J., and Bouma, Berto J.

Published
2021

92. Doppler gradients, valve area and ventricular function in pregnant women with aortic or pulmonary valve disease: Left versus right

Author

Team Medisch, Circulatory Health, Siegmund, Anne S., Pieper, Petronella G., Mulder, Barbara J.M., Sieswerda, Gertjan Tj, van Dijk, Arie P.J., Roos-Hesselink, Jolien W., Jongbloed, Monique R.M., Konings, Thelma C., Bouma, Berto J., Groen, Henk, Sollie-Szarynska, Krystyna M., Kampman, Marlies A.M., Bilardo, Caterina M., van Veldhuisen, Dirk J., Aalberts, Jan J.J., Team Medisch, Circulatory Health, Siegmund, Anne S., Pieper, Petronella G., Mulder, Barbara J.M., Sieswerda, Gertjan Tj, van Dijk, Arie P.J., Roos-Hesselink, Jolien W., Jongbloed, Monique R.M., Konings, Thelma C., Bouma, Berto J., Groen, Henk, Sollie-Szarynska, Krystyna M., Kampman, Marlies A.M., Bilardo, Caterina M., van Veldhuisen, Dirk J., and Aalberts, Jan J.J.

Published
2020

96. Cardiovascular magnetic resonance in the follow-up of patients with corrected tetralogy of Fallot: A review

Author

Oosterhof, Thomas, Mulder, Barbara J.M., Vliegen, Hubert W., and De Roos, Albert

Subjects
Tetralogy of Fallot, Genetic disorders, Cardiac patients, Health
Abstract

To link to full-text access for this article, visit this link: http://dx.doi.org/10.1016/j.ahj.2005.03.058 Byline: Thomas Oosterhof (a)(c), Barbara J.M. Mulder (c), Hubert W. Vliegen (b), Albert de Roos (a) Abstract: Cardiovascular magnetic resonance (CMR) is becoming an important tool in the clinical management of patients with congenital heart disease. Because of the diverse problems patients may face after initial correction for tetralogy of Fallot and the large amount of CMR techniques that can be applied, creating a patient-orientated imaging protocol is a difficult issue. Although it is still not certain what the impact of some parameters, provided by CMR, should be on clinical decision making, new techniques are being developed and applied. In this report, we review the current clinical issues in patients with tetralogy of Fallot and review the current implication and limitations of CMR in this patient category. Author Affiliation: (a) Department of Radiology, Leiden University Medical Center, Leyden, The Netherlands (b) Department of Cardiology, Leiden University Medical Center, Leyden, The Netherlands (c) Department of Cardiology, Academic Medical Center, Amsterdam, The Netherlands Article History: Received 10 February 2005; Accepted 26 March 2005

Published
2006

97. Increased carotid and femoral intima-media thickness in patients after repair of aortic coarctation: Influence of early repair

Author

Vriend, Joris W.J., De Groot, Eric, De Waal, Tim T., Zijta, Frank M., Kastelein, John J.P., and Mulder, Barbara J.M.

Subjects
Aortic coarctation, Health
Abstract

To link to full-text access for this article, visit this link: http://dx.doi.org/10.1016/j.ahj.2005.02.013 Byline: Joris W.J. Vriend (a), Eric de Groot (b), Tim T. de Waal (b), Frank M. Zijta (b), John J.P. Kastelein (b), Barbara J.M. Mulder (a) Abstract: In patients, after repair of aortic coarctation, abnormal function of the proximal precoarctation arterial conduits has been demonstrated, but data on arterial wall structure of proximal and distal arteries in patients are scarce. The aim of our study is to compare intima-media thickness (IMT) of the carotid and femoral arteries in controls and patients after coarctation repair and to identify independent predictors of carotid and femoral IMT. Author Affiliation: (a) Department of Cardiology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands (b) Department of Vascular Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands Article History: Received 10 September 2004; Accepted 14 February 2005

Published
2006

98. Safety and efficacy of non-vitamin K antagonist oral anticoagulants for prevention of thromboembolism in adults with systemic right ventricle: Results from the NOTE international registry

Author

Scognamiglio, Giancarlo, primary, Fusco, Flavia, additional, Hankel, Tara C., additional, Bouma, Berto J., additional, Greutmann, Matthias, additional, Khairy, Paul, additional, Ladouceur, Magalie, additional, Dimopoulos, Konstantinos, additional, Niwa, Koichiro, additional, Broberg, Craig S., additional, Miranda, Berta, additional, Budts, Werner, additional, Bouchardy, Judith, additional, Schwerzmann, Markus, additional, Lipczyńska, Magdalena, additional, Tobler, Daniel, additional, Tsai, Shane F., additional, Egbe, Alexander C., additional, Aboulhosn, Jamil, additional, Fernandes, Susan M., additional, Garr, BreAnn, additional, Rutz, Tobias, additional, Mizuno, Atsushi, additional, Proietti, Anna, additional, Alonso-Gonzalez, Rafael, additional, Mulder, Barbara J.M., additional, and Sarubbi, Berardo, additional

Published
2021
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