88 results on '"Moya-Mur JL"'
Search Results
52. Left ventricular vortices as observed by vector flow mapping: main determinants and their relation to left ventricular filling.
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Rodríguez Muñoz D, Moya Mur JL, Fernández-Golfín C, Becker Filho DC, González Gómez A, Fernández Santos S, Lázaro Rivera C, Rincón Díaz LM, Casas Rojo E, and Zamorano Gómez JL
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- Double-Blind Method, Female, Humans, Male, Middle Aged, Reproducibility of Results, Rheology methods, Sensitivity and Specificity, Blood Flow Velocity, Echocardiography methods, Heart Ventricles physiopathology, Image Interpretation, Computer-Assisted methods, Ventricular Dysfunction, Left diagnostic imaging, Ventricular Dysfunction, Left physiopathology
- Abstract
Background: Swirling flow, organized in vortices, contributes to adequate left ventricular function. In this study, we apply a novel echocardiographic flow-mapping technique, vector flow mapping (VFM), to evaluate the main characteristics of left ventricular vortices and its relation to filling parameters., Methods: Forty-eight subjects underwent conventional transthoracic echocardiographic examination with additional intracardiac flow assessment with VFM using a Aloka Alpha-10 system and experimental VFM analysis software. To analyze vortex behavior, its rotation direction, duration, location inside the left ventricle, size, and intensity were assessed in apical long-axis view. Its relation to conventional left ventricular filling parameters was then analyzed., Results: Two vortex components were consistently identified following each transmitral filling wave. The anterior component of these visualized vortices was analyzed, due to its higher significance in the cardiac cycle, following early filling (V1) and atrial contraction (V2). Differences were observed in several aspects of vortex behavior between V1 and V2, particularly in patients with normal left ventricular filling parameters. These differences may be related to varying roles of vortices in different periods of the cardiac cycle., Conclusions: Vector flow mapping allowed visualization and measurement of several parameters defining vortex behavior inside the cardiac cycle. The differences observed in these parameters between vortices in different phases of the cardiac cycle may be related to their role in optimizing cardiac function., (© 2014, Wiley Periodicals, Inc.)
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- 2015
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53. Long-term survival of chronic left ventricular pseudoaneurysm in elderly adults. Is surgery the best option?
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García-Lledó A, Moya-Mur JL, de Juan J, García-Pérez-Velasco J, Sanz A, and Díaz-Caraballo E
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- Aged, Aged, 80 and over, Aneurysm, False mortality, Aneurysm, False surgery, Chronic Disease, Female, Follow-Up Studies, Heart Aneurysm mortality, Heart Aneurysm surgery, Heart Rupture, Post-Infarction mortality, Heart Rupture, Post-Infarction surgery, Hospitals, Public, Humans, Incidental Findings, Kaplan-Meier Estimate, Male, Retrospective Studies, Spain, Ventricular Dysfunction, Left mortality, Ventricular Dysfunction, Left surgery, Aneurysm, False diagnosis, Heart Aneurysm diagnosis, Heart Rupture, Post-Infarction diagnosis, Survivors, Ventricular Dysfunction, Left diagnosis
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- 2014
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54. Nonvalvular atrial fibrillation: the problem of an undefined definition.
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García-Lledó A, Moya Mur JL, Balaguer Recena J, Díaz Caraballo E, García Pérez-Velasco J, and Sanz Barrio A
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- Anticoagulants therapeutic use, Atrial Fibrillation complications, Humans, Stroke etiology, Atrial Fibrillation drug therapy, Stroke prevention & control, Warfarin therapeutic use
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- 2014
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55. Alcohol septal ablation in hypertrophic cardiomyopathy. 3D contrast echocardiography allows localization and quantification of the extension of intraprocedural vascular recruitment.
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Moya Mur JL, Salido Tahoces L, Mestre Barceló JL, Rodríguez Muñoz D, Hernández R, Fernández-Golfín C, and Zamorano Gómez JL
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- Aged, Cardiomyopathy, Hypertrophic surgery, Echocardiography methods, Female, Heart Septum surgery, Humans, Cardiomyopathy, Hypertrophic diagnostic imaging, Echocardiography, Three-Dimensional methods, Ethanol administration & dosage, Heart Septum diagnostic imaging, Monitoring, Intraoperative methods
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- 2014
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56. Cor triatriatum sinister.
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Moya Mur JL, Centella-Hernández T, Reyes Villanes JS, Fernandez Golfín C, and Zamorano Gómez JL
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- Adult, Female, Humans, Monitoring, Physiologic, Sensitivity and Specificity, Severity of Illness Index, Cor Triatriatum diagnostic imaging, Echocardiography methods, Echocardiography, Three-Dimensional methods
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- 2014
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57. Three-dimensional contrast echocardiography-guided alcohol septal ablation in hypertrophic obstructive cardiomyopathy.
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Moya Mur JL, Salido Tahoces L, Mestre Barcelo JL, Fernandez Golfín C, and Zamorano Gómez JL
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- Cardiomyopathy, Hypertrophic diagnostic imaging, Female, Heart Septum diagnostic imaging, Humans, Middle Aged, Ablation Techniques methods, Cardiomyopathy, Hypertrophic therapy, Echocardiography, Three-Dimensional, Ethanol therapeutic use, Heart Septum drug effects, Ultrasonography, Interventional methods
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- 2014
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58. Flow mapping inside a left ventricular aneurism: a potential tool to demonstrate thrombogenicity.
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Rodriguez Muñoz D, Moya Mur JL, Becker Filho DC, Rincon Díaz LM, Gonzalez Gómez A, Fernández-Golfín C, and Zamorano Gómez JL
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- Aged, Feasibility Studies, Humans, Male, Rheology methods, Echocardiography methods, Heart Aneurysm complications, Heart Aneurysm diagnostic imaging, Thrombosis diagnostic imaging, Thrombosis etiology, Ventricular Dysfunction, Left diagnostic imaging, Ventricular Dysfunction, Left etiology
- Abstract
We describe the use of vector flow mapping (VFM), a novel echocardiographic technique allowing intracardiac flow visualization, to quantify flow intensity inside a left ventricular aneurysm in a 68-year-old man. VFM successfully identified areas of stagnant flow corresponding to the wall region where a thrombus had been formed., (© 2013, Wiley Periodicals, Inc.)
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- 2014
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59. Carcinoid heart disease: the winking heart.
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García Martín A, Moya Mur JL, Fernández Golfín C, and Zamorano Gómez JL
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- 2013
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60. Intracardiac flow visualization: current status and future directions.
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Rodriguez Muñoz D, Markl M, Moya Mur JL, Barker A, Fernández-Golfín C, Lancellotti P, and Zamorano Gómez JL
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- Blood Flow Velocity physiology, Echocardiography, Doppler, Color trends, Female, Forecasting, Heart Diseases diagnosis, Humans, Imaging, Three-Dimensional trends, Magnetic Resonance Imaging, Cine trends, Male, Myocardial Perfusion Imaging, Quality Control, Sensitivity and Specificity, Coronary Circulation physiology, Echocardiography, Doppler, Color standards, Imaging, Three-Dimensional standards, Magnetic Resonance Angiography standards, Magnetic Resonance Imaging, Cine standards
- Abstract
Non-invasive cardiovascular imaging initially focused on heart structures, allowing the visualization of their motion and inferring its functional status from it. Colour-Doppler and cardiac magnetic resonance (CMR) have allowed a visual approach to intracardiac flow behaviour, as well as measuring its velocity at single selected spots. Recently, the application of new technologies to medical use and, particularly, to cardiology has allowed, through different algorithms in CMR and applications of ultrasound-related techniques, the description and analysis of flow behaviour in all points and directions of the selected region, creating the opportunity to incorporate new data reflecting cardiac performance to cardiovascular imaging. The following review provides an overview of the currently available imaging techniques that enable flow visualization, as well as its present and future applications based on the available literature and on-going works.
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- 2013
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61. Nonvalvular atrial aneurysmal dilation.
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Moya-Mur JL, Becker-Filho D, Jiménez-Nacher JJ, García-Lledó A, Fernández-Golfin C, and Zamorano-Gómez JL
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- Aged, Aged, 80 and over, Aortic Aneurysm complications, Aortic Aneurysm diagnostic imaging, Echocardiography, Female, Heart Diseases etiology, Humans, Male, Aortic Aneurysm pathology
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- 2013
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62. Double-orifice tricuspid annulus.
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Moya Mur JL, Becker Filho DC, Rodríguez Muñoz D, Haertel Miglioranza M, Epeldegui Torres A, Fernández Golfín C, and Zamorano Gómez JL
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- Humans, Postoperative Complications etiology, Ultrasonography, Postoperative Complications diagnostic imaging, Tricuspid Valve diagnostic imaging, Tricuspid Valve surgery
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- 2013
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63. Right atrial rupture in angiosarcoma.
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Moya Mur JL, Oliva Danquin E, Jiménez Nacher JJ, Fernández-Golfin C, and Zamorano J
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- Adult, Chest Pain etiology, Echocardiography, Echocardiography, Doppler, Color, Echocardiography, Transesophageal, Hemangiosarcoma surgery, Humans, Imaging, Three-Dimensional, Male, Mediastinal Neoplasms surgery, Neoplasm Invasiveness, Rupture diagnostic imaging, Rupture etiology, Heart Atria diagnostic imaging, Heart Atria injuries, Hemangiosarcoma diagnosis, Mediastinal Neoplasms diagnosis
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- 2013
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64. Double-orifice tricuspid valve in Ebstein's anomaly.
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Moya Mur JL, González Ferrer E, Jiménez Nacher JJ, Centella T, and Zamorano J
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- Adult, Ebstein Anomaly physiopathology, Electrocardiography methods, Humans, Male, Sensitivity and Specificity, Severity of Illness Index, Tricuspid Valve diagnostic imaging, Ultrasonography, Doppler, Color methods, Ebstein Anomaly diagnostic imaging, Echocardiography methods, Imaging, Three-Dimensional, Tricuspid Valve abnormalities
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- 2013
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65. Giant pseudoaneurysm of a saphenous vein graft.
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del Castillo Carnevali H, Recio Vázquez M, Moya Mur JL, Barrios Alonso V, and Zamorano JL
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- Aged, Aneurysm, False surgery, Diagnosis, Differential, Echocardiography, Electrocardiography, Humans, Male, Radiography, Thoracic, Tomography, X-Ray Computed, Aneurysm, False diagnosis, Coronary Artery Bypass, Saphenous Vein transplantation
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- 2012
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66. Two cases of atypical presentation of papillary fibroelastoma.
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Briongos Figuero S, Gerardo Pian H, Moya Mur JL, and Fernández Espino R
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- Aged, Aortic Valve diagnostic imaging, Aortic Valve pathology, Echocardiography, Transesophageal, Female, Fibroma diagnosis, Heart Atria pathology, Heart Failure etiology, Heart Neoplasms diagnosis, Humans, Male, Middle Aged, Mitral Valve Insufficiency complications, Fibroma pathology, Heart Neoplasms pathology
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- 2012
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67. Selecting the best site for pacing leads after cardiac surgery by evaluating the asynchrony of myocardial deformation observed with different pacing sites.
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Moya-Mur JL, Oliva-De Anquin E, Centella-Hernández T, Ruiz-Leira S, Megías-Sáez A, Tomás-Zarlenga JP, Hernández-Madrid A, García-Galloway E, and Moro C
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- Aged, Echocardiography, Electrodes, Implanted, Female, Heart physiology, Heart Ventricles diagnostic imaging, Heart Ventricles physiopathology, Humans, Male, Middle Aged, Reproducibility of Results, Cardiac Pacing, Artificial methods, Cardiac Surgical Procedures, Electrocardiography, Myocardium pathology, Pacemaker, Artificial
- Abstract
Introduction and Objectives: After cardiac surgery, temporary pacing leads are routinely implanted in the right ventricle (RV). The objective was to investigate the effect of different ventricular pacing locations on cardiac synchrony (by evaluating myocardial deformation, or strain) and efficiency in patients undergoing cardiac surgery., Methods: Interventricular asynchrony (i.e. the difference in the time of onset of deformation between right and left ventricles; Tε-R/L) and intraventricular asynchrony (i.e. the standard deviation and maximum difference in the time of onset of deformation in six segments of the left ventricle [LV]; Tε-SD and Tε-MD, respectively) were assessed in 19 patients. Doppler echocardiography was used to evaluate these parameters and cardiac output after pacing in the RV and in three different LV segments., Results: Pacing in the RV resulted in the greatest increases in asynchrony parameters from baseline: Tε-R/L 59.8 ms (standard deviation [SD] 40.5 ms) vs. 28.23 ms (SD 56.9 ms), P=.002; Tε-SD 53.2 ms (SD 34.4 ms) vs. 36.6 ms (SD 34.9 ms), P=.007; and Tε-MD 135.3 ms (SD 82.9 ms) vs. 90.5 ms (SD 87.4 ms), P=.007. Pacing in the LV resulted in less asynchrony: for anterior LV pacing, Tε-R/L was 17.2 ms (SD 53.8 ms), Tε-SD was 35.8 ms (SD 17.9 ms), and Tε-MD was 91.3 ms (SD 45.2). The change from baseline was not significant. Cardiac output was lower after RV pacing than after anterior LV pacing: 4.36 (SD 1) vs. 4.70 (SD 1); P=.001., Conclusions: Pacing in the LV produced less asynchrony than RV pacing. In addition, anterior LV pacing resulted in a higher cardiac output than RV pacing. These findings suggest that the location normally used for temporary leads after cardiac surgery should be changed.
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- 2010
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68. Indexed left atrial volume is a more sensitive indicator of filling pressures and left heart function than is anteroposterior left atrial diameter.
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Moya-Mur JL, García-Martín A, García-Lledó A, Ruiz-Leria S, Jiménez-Nacher JJ, Megias-Sanz A, Taboada D, and Muriel A
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- Adult, Aged, Aged, 80 and over, Blood Pressure, Female, Humans, Image Enhancement methods, Male, Middle Aged, Organ Size, Reproducibility of Results, Sensitivity and Specificity, Young Adult, Algorithms, Blood Pressure Determination methods, Echocardiography methods, Heart Atria diagnostic imaging, Image Interpretation, Computer-Assisted methods, Imaging, Three-Dimensional methods
- Abstract
Introduction: Left atrial (LA) size is an indicator of the pressure to which it is chronically subjected. Although guidelines recommend measuring it using volume indexed to body surface, the anteroposterior diameter is still normally used., Aim: To evaluate which of these measurements correlates better with atrial pressure-related echocardiographic parameters., Methods: Atrial diameter and volume, together with parameters of systolic function, diastolic function, pressure, and degree of mitral regurgitation, were measured in 121 consecutive outpatients., Results: Atrial diameter correlated with its indexed volume (r: 0.69) with a low degree of agreement for detecting dilation (Kappa: 0.51). Atrial diameter was related to the parameters associated with atrial pressure: E/E' (r: 0.44), pulmonary vein systolic/diastolic rates quotient (r: 0.25) and degree of mitral regurgitation (r: 0.19). The correlations improved when volume indexed to body surface was measured (r: 0.52; 0.38 and 0.44, respectively). In a multiple regression analysis that included E/E', pulmonary vein flow and degree of mitral regurgitation, LA diameter depended entirely on E/E' (r: 0.44; B: 0.04; P: 0.000). The relationship improved when the diameter was corrected for body surface or the volume was measured (r: 0.54 and 0.54, respectively), and in particular when volume indexed to body surface was measured (r: 0.66). In this case, pulmonary vein flow (B: 6.8; P: 0.03), degree of mitral regurgitation (B: 5.2; P: 0.000) and E/E' ratio (B: 0.8; P : 0.000) were included in the equation., Conclusions: Indexed atrial volume correlates better with LA pressure surrogates than the anteroposterior diameter, even when this is corrected for body surface., (© 2010, Wiley Periodicals, Inc.)
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- 2010
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69. [Update in cardiac imaging techniques. Echocardiography and magnetic resonance imaging].
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Laraudogoitia Zaldumbide E and Moya Mur JL
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- Humans, Ultrasonography, Heart Diseases diagnostic imaging, Heart Diseases pathology, Magnetic Resonance Imaging
- Abstract
This article is a review of the main developments in cardiac imaging techniques reported in publications during 2005. Recent advances in digital technology have led to steadily increasing reliance on imaging techniques in the management of cardiovascular disease. We discuss advances in two techniques that fall under the remit of the echocardiography working group: echocardiography and magnetic resonance imaging.
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- 2006
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70. [Closure of an iatrogenic coronary artery fistula with a PTFE-coated stent].
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Mestre Barceló JL, Salido Tahoces L, del Río del Busto A, Camino López A, Moya Mur JL, and Pey Illera J
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- Coated Materials, Biocompatible, Heart Ventricles, Humans, Iatrogenic Disease, Male, Middle Aged, Coronary Vessels surgery, Polytetrafluoroethylene, Stents, Vascular Fistula therapy
- Abstract
Acquired coronary-cameral fistula is an uncommon disorder. We describe a 50-year-old man with rheumatic valvular disease who required emergency mitral and aortic valve replacement due to Staphylococcus aureus acute infective endocarditis. He underwent further surgical interventions due to bleeding and prosthetic dehiscence. During follow-up, a continuous parasternal murmur was noted. Echocardiography showed continuous coronary fistula flow from the left anterior descending artery to the right ventricle. Elective closure of the ostium was achieved with direct implantation of a 3.5 x 16 mm PTFE-coated stent (Jostent Coronary System Graft, Jomed, Germany).
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- 2004
71. [Cardiac resynchronization for heart failure: background, methods, indications and results].
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Hernández Madrid A, Escobar Cervantes C, Blanco Tirado B, Marín Marín I, Moya Mur JL, and Moro C
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- Clinical Trials as Topic, Heart Failure physiopathology, Humans, Defibrillators, Implantable, Heart Failure therapy, Pacemaker, Artificial
- Abstract
Heart failure is one of the most prevalent diseases in industrialized countries. Although the prognosis of patients with heart failure is still poor, in recent decades new therapies have been investigated in order to improve quality of life and survival. However, up to 30% of the patients with advanced heart failure present disturbances in intraventricular conduction, and this produces asynchrony of ventricular contractility, leading to further deterioration in heart function. Cardiac resynchronization therapy can improve the synchrony of ventricular contractility. Numerous studies have demonstrated the benefits of biventricular stimulation therapy for improving hemodynamic parameters, quality of life, 6-minute walking test performance and functional class in patients with heart failure, ventricular systolic dysfunction and disturbances in intraventricular conduction. Some studies have demonstrated longer survival times in patients treated with cardiac resynchronization plus a defibrillator. Nonetheless, many questions about the benefits of heart resynchronization therapy, site of stimulation and best type of device (pacemaker or defibrillator) remain unresolved.
- Published
- 2004
72. [Usefulness of brain natriuretic peptide to evaluate patients with heart failure treated with cardiac resynchronization].
- Author
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Hernández Madrid A, Miguelañez Díaz M, Escobar Cervantes C, Blanco Tirados B, Marín I, Bernal E, Zamora J, Cordova González FJ, Alfonso Pérez M, Limón L, González Rebollo JM, Moya Mur JL, and Moro C
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- Aged, Cardiac Pacing, Artificial, Female, Heart Failure therapy, Humans, Male, Heart Failure blood, Natriuretic Peptide, Brain blood
- Abstract
Introduction and Objectives: The aim of the present study was to document the evolution of the blood levels of brain natriuretic peptide (BNP) in patients with heart failure and their correlation with the clinical course after implantation of a biventricular pacemaker., Patients and Method: Twenty-eight patients with heart failure associated to left bundle branch block and left ventricular systolic dysfunction were included in the study. In each patient we performed laboratory tests, chest X-ray, electrocardiogram and echocardiogram, and measured blood levels of BNP., Results: During follow-up (10 [6] months) functional capacity improved, decreasing from 3.3 (0.6) to 2.10 (0.4) (P=.03). The rate of hospitalizations for heart failure decreased from an average of 1.8 (0.7) (6 months before the procedure) to 0.8 (0.3) (6 months after the procedure; P=.04). The basal value of BNP decreased from 193 (98) pg/mL to 52 (14) at the end of the follow-up in the responder group (22 patients) and increased from 564 (380) to 650 (80) pg/mL in the nonresponder group (6 patients). Patients who responded showed significant clinical improvement and decreasing levels of BNP, which reached a plateau an average of 6 months after implantation. Multivariate logistic regression analysis identified lower levels of BNP, idiopathic dilated cardiomyopathy, and functional class as independent predictors of response to therapy. Age, QRS width and left ventricular ejection fraction were not predictors of response., Conclusions: Brain natriuretic peptide concentrations allowed us to monitor, in an objective manner, the clinical course of patients with biventricular resynchronization therapy.
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- 2004
73. Role of noninvasive antimyosin imaging in infants and children with clinically suspected myocarditis.
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Martin ME, Moya-Mur JL, Casanova M, Crespo-Diez A, Asin-Cardiel E, Castro-Beiras JM, Diez-Jimenez L, Ballester M, Carrio I, and Narula J
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- Adolescent, Child, Child, Preschool, Comorbidity, Disease Progression, Female, Humans, Infant, Male, Myocarditis pathology, Prognosis, Radionuclide Imaging, Radiopharmaceuticals, Reproducibility of Results, Sensitivity and Specificity, Spain epidemiology, Survival Analysis, Ventricular Dysfunction, Left pathology, Immunoglobulin Fab Fragments, Myocarditis diagnostic imaging, Myocarditis mortality, Pentetic Acid analogs & derivatives, Ventricular Dysfunction, Left diagnostic imaging, Ventricular Dysfunction, Left mortality
- Abstract
Unlabelled: Endomyocardial biopsy is an invasive procedure, often performed on children for the diagnosis of myocarditis, and is not without risk. Therefore, a noninvasive test of adequate diagnostic accuracy is highly desirable. We evaluated the role of antimyosin scintigraphy in infants and children with clinically suspected myocarditis., Methods: Forty patients (age range, 2 mo to 14 y) with suspected myocarditis underwent (111)In-antimyosin scintigraphy. All patients were clinically followed for 29 +/- 17 mo; 21 patients underwent serial antimyosin scans (3.8 +/- 1.7 per patient). The antimyosin uptake was assessed by heart-to-lung ratio (HLR). The scan results were compared with endomyocardial biopsy results in 22 patients., Results: Thirty-five of the 40 patients showed abnormal antimyosin findings; 17 patients showed intense myocardial antimyosin uptake (HLR > 2). The HLR was higher in patients presenting within the first 2 mo of illness (2.09 +/- 0.43 vs. 1.74 +/- 0.34, P = 0.01). Of 22 patients with endomyocardial biopsy, 17 demonstrated myocarditis. All 9 patients who had an HLR > 2 and underwent endomyocardial biopsy had histologic evidence of myocarditis. Of the remaining 13 patients with HLR < 2, 8 had biopsy-verified myocarditis (62%). The intensity of antimyosin uptake was the major determinant of survival in children, with a relative risk of 18 (confidence interval, 1.34-242; P = 0.027). High antimyosin uptake (HLR > 2) seen within 2 mo of the onset of symptoms was associated with a higher mortality rate. The survivors with an HLR > 2 and those with an HLR < 2 showed a high likelihood of complete functional recovery. Furthermore, the patients with serial antimyosin scans having persistently positive findings showed a poor clinical outcome., Conclusion: Intense myocardial uptake of antimyosin antibody is a reliable indicator of myocarditis in infants and children. Severe myocardial damage detected in the early phase of disease is associated with a higher mortality rate. The persistence of antimyosin uptake is associated with poor clinical outcomes.
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- 2004
74. [Yield of transthoracic echocardiography with high frequency transducer in the study of the anterior descending coronary artery].
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Moya Mur JL, Guzmán G, Catalán P, Megías A, Ruiz S, Barrios V, Ortega J, de Pablo C, Harriague C, García Lledó A, and Asín Cardiel E
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- Aged, Female, Humans, Male, Middle Aged, Coronary Vessels diagnostic imaging, Echocardiography, Transesophageal instrumentation, Myocardial Infarction diagnostic imaging
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Introduction and Objectives: This study was performed to evaluate the feasibility and utility of a transthoracic high frequency transducer to detect and measure the left anterior descending coronary artery flow in patients with lesions in this artery or anterior myocardial infarction., Materials and Methods: We studied 11 subjects with lesions greater than 75% and another 10 with anterior myocardial infarction. We compared the results with a control group of 18 subjects. An ATL HDI 5000 ultrasound unit with a 5-8 MHz transducer was used to identify the left anterior descending in the anterior interventricular sulcus from an apical four chamber window. We considered that left anterior descending was detected when a diastolic predominant flow pattern was obtained with pulse Doppler., Results: Left anterior descending was detected in 37/39 of cases (94.4%). Patients with coronary lesions showed a decrease in the limit of significance in the diastolic/systolic peak velocity ratios: 2.5 (SD 0.7) vs 1.8 (SD 0.3) with a p = 0.024. Patients with anterior myocardial infarction obtained lower diastolic/systolic peak velocity ratios than controls: 2.5 (SD 0.7) vs 1.4 (SD 0.3) with a p = 0.001., Conclusions: Left anterior descending coronary artery flow can be assessed by transthoracic high frequency echocardiography in greater than 90% of the cases. Patients with coronary lesions and those with anterior myocardial infarction have a decreased diastolic/systolic peak velocity ratio.
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- 2001
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75. [Hepatopulmonary syndrome].
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Aller de la Fuente R, Moreira Vicente V, Moya Mur JL, Boixeda de Miquel D, and de Luis Román DA
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- Adult, Diagnosis, Differential, Female, Humans, Hypertension, Portal physiopathology, Liver Circulation, Liver Cirrhosis physiopathology, Male, Pulmonary Circulation, Vasoconstriction, Vasodilation, Hepatopulmonary Syndrome diagnosis, Hepatopulmonary Syndrome physiopathology, Hepatopulmonary Syndrome therapy
- Published
- 1999
76. [A simplified method of continuous-wave Doppler noninvasive assessment of ventricular relaxation in mitral insufficiency].
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García Lledó JA, Moya Mur JL, Balaguer Recena J, Novo García E, Correa Gorospe C, Jorge P, Barea Navarro R, and Boquete L
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- Animals, Data Interpretation, Statistical, Diastole, Observer Variation, Reproducibility of Results, Swine, Ventricular Pressure physiology, Echocardiography, Doppler, Mitral Valve Insufficiency physiopathology, Ventricular Function physiology
- Abstract
Introduction and Objectives: The minimum value of dP/dT is a parameter of diastolic function that can be estimated noninvasively by analyzing the profile of velocity of the mitral regurgitant jet, recorded by continuous-wave Doppler. This estimation requires a complex analysis of the curves that impedes its practical use. Our objective was to validate a simplified method to estimate noninvasively the value of dP/dTmin when mitral regurgitation exists. We calculated the pendient of the profile of velocity of the curve of mitral regurgitation during its deceleration, between 3 and 1.5 m/s, an interval that defines a difference in pressure using the formula delta p = (4v2(1) - 4v2(2)). We divided this interval by the time needed by the jet to decelerate from 3 to 1.5 m/s, obtaining the rate of pressure decay, in mmHg/s., Methods: We provoked mitral regurgitation in five pigs and registered dP/dT and the curve velocity of mitral regurgitation simultaneously, by micromanometer-tipped catheter and continuous-wave Doppler, respectively. The rate of pressure decay was calculated on the mitral regurgitation curve., Results: We obtained 29 simultaneous registers. The coefficient for the correlationship between dP/dT and the rate of pressure decay was with an r value of 0.62 (p < 0.0001). The rate of pressure decay underestimated systematically the value of dP/dT. Intra and interobserver variability of TDP was 9 and 11%, respectively., Conclusions: This study validates a simplified method to estimate dP/dT noninvasively, with acceptable correlation with invasive measurements and adequate reproducibility.
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- 1998
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77. [Study of active myocardial damage in children with suspected myocarditis using antimyosin monoclonal antibodies (AMMoAb-111In)].
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Rioja Martín ME, Moya Mur JL, Casanova M, Castro Beiras JM, Asín Cardiel E, Díez Jiménez L, and Crespo Díez A
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- Child, Child, Preschool, Female, Humans, Indium Radioisotopes, Infant, Male, Radionuclide Imaging, Retrospective Studies, Time Factors, Antibodies, Monoclonal, Myocarditis diagnostic imaging, Organometallic Compounds
- Abstract
Background: The study with monoclonal antimyosin antibody-111In has proved to be useful in the detection of the myocardial damage present in different processes. There is active myocardial damage and specific antimyosin uptake in myocarditis, as both experimental and clinical trials have shown. In experimental models the evolution of myocardial damage has been studied, where a parallelism between the histological changes of the myocardial damage and the evolution on the antimyosin uptake has been found. In clinical myocarditis it is difficult to do an histological follow up of the inflammatory process, and therefore the evolution of myocardial damage present in myocarditis is unknown. The antimyosin antibody images allow a non-invasive study of this evolution., Objectives: a) to study with monoclonal antimyosin antibody-111In, the myocardial damage present regarding the disease evolution in children with suspected clinical diagnosis of myocarditis; b) to evaluate the evolution of the active myocardial damage reflected on the changes on the monoclonal antimyosin antibody-111In uptake., Methods: A study with monoclonal antimyosin antibody-111In was carried out on 43 children, 16 males and 27 females with a median age of 39 months (SD 48 m; range: 2-167) with suspected diagnosis of acute myocarditis defined as the presence of congestive cardiac failure or severe ventricular arrhythmia with less than 12 months of evolution. The image evaluation was done visually and through the heart to lung ratio. Twenty of these patients were also followed up with antimyosin antibody scan for a period of 19 +/- 9 months, and 3.8 +/- 1.7 studies were performed on them in this time., Results: The prevalence of positive myocardial uptake was 83.72%. There is a negative correlation (r = -0.352; p < 0.02) between the evolution time of the process and the heart to lung ratio: patients studied before two months, have a higher heart to lung ratio and greater prevalence of positive studies than those studied later (heart to lung ratio 2.09 vs 1.74; p = 0.013; 90% vs 69.2%). Of the patients followed up with antimyosin antibody scans, 6 showed a clinical relapse which increased their heart to lung ratio. The other 14 showed an progressive decrease of the heart to lung ratio reaching normality in 14 +/- 6 months., Conclusions: a) the uptake intensity of monoclonal antimyosin antibody-111In, as a reflection of the myocardial damage, depends on the disease evolution time, as in the first two months is when the major damage happens; b) the uptake intensity slowly decreases, tending to normality around the 14th month, although this evolution may be altered by the appearance of relapses.
- Published
- 1998
78. Cardiac involvement in acromegaly: specific myocardiopathy or consequence of systemic hypertension?
- Author
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López-Velasco R, Escobar-Morreale HF, Vega B, Villa E, Sancho JM, Moya-Mur JL, and García-Robles R
- Subjects
- Acromegaly physiopathology, Adult, Cross-Sectional Studies, Diastole, Echocardiography, Female, Follow-Up Studies, Heart physiopathology, Humans, Male, Middle Aged, Systole, Acromegaly complications, Acromegaly diagnostic imaging, Cardiomyopathies etiology, Hypertension etiology
- Abstract
To evaluate the relative contributions of past or present GH hypersecretion and of hypertension to the cardiac abnormalities present in acromegaly, we have studied the serum GH and insulin-like growth factor I concentrations, systolic and diastolic blood pressures, and morphological and functional cardiac indexes as measured by echocardiography-Doppler, in 39 patients with active or cured acromegaly, 16 hypertensive controls, and 17 normotensive controls. Hypertension was present in 42.8% of patients with active acromegaly and in 28.0% of patients in which acromegaly was cured. Hypertension was independently related to an increase in indexes of cardiac morphology (left ventricular mass, left ventricular posterior wall thickness, interventricular septum thickness, relative wall thickness with respect to the diastolic diameter of the left ventricle, and left atrial end-systolic diameter), systolic function (stroke volume, fractional shortening, and end-systolic stress), and diastolic function (isovolumic relaxation time and maximal late diastolic flow velocity) and to a reduction in the early to late maximal diastolic flow velocity ratio. Acromegaly was related to an increase in left ventricular mass, stroke volume, cardiac output, and isovolumic relaxation time, which were independent from the presence of hypertension. End-systolic stress was reduced by acromegaly. In the five patients in which active acromegaly was successfully treated, left ventricular mass and left ventricular posterior wall thickness were reduced 1 yr later. In conclusion, the asymptomatic morphological and functional cardiac abnormalities present in acromegalic patients are independently related to acromegaly and hypertension, pointing to the existence to a specific acromegalic myocardiopathy that might be aggravated by the coexistence of hypertension.
- Published
- 1997
- Full Text
- View/download PDF
79. [Penetrating trauma by foreign body in the left heart ventricle].
- Author
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García-Lledó JA, Moya Mur JL, Balaguer Recena J, Novo García E, Sancho Piedras JM, Sáiz Beneit R, Rubio Cantarero C, Epeldegui Torre A, and Oliva de Anquín E
- Subjects
- Adult, Echocardiography, Transesophageal, Foreign Bodies diagnostic imaging, Foreign Bodies surgery, Heart Injuries diagnostic imaging, Heart Ventricles injuries, Humans, Male, Radiography, Wounds, Penetrating diagnostic imaging, Wounds, Penetrating surgery, Foreign Bodies complications, Heart Injuries etiology, Wounds, Penetrating complications
- Abstract
We present the case of a patient who suffered a cardiac penetrating trauma due to a 6-cm long steel splinter. He was self-admitted to the emergency room and was asymptomatic. Cardiac trauma was diagnosed by the presence of a foreign body in his chest X-ray. Transthoracic and transesophageal echocardiography showed pericardial effusion and a dense foreign body that crossed the left ventricle from upside down and forward to back. The patient underwent cardiac surgery under extracorporal circulation. A shooting wound was seen on the left ventricular free wall. Transesophageal echocardiography was performed during surgery in order to define the position of the foreign body and to discard lesions due to multidirectional injury. Lesions were repaired and the patient was discharged with no complications. This case report illustrates the possibility of survival after cardiac penetrating trauma, and the role of echocardiography in the diagnosis and surgical repair of this type of trauma.
- Published
- 1997
- Full Text
- View/download PDF
80. [Doppler echocardiography in hypertrophic myocardiopathy].
- Author
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Asín Cardiel E and Moya Mur JL
- Subjects
- Aorta physiopathology, Cardiomyopathy, Hypertrophic complications, Cardiomyopathy, Hypertrophic physiopathology, Diastole, Humans, Hypertrophy, Left Ventricular etiology, Mitral Valve physiopathology, Cardiomyopathy, Hypertrophic diagnostic imaging, Echocardiography, Doppler
- Abstract
Hypertrophic cardiomiopathy is a peculiar process with different anatomical and functional abnormalities which are present in different degrees in each case. Echocardiography and Doppler techniques have contributed definitively to the knowledge of this process and these procedures are choices for establishing the diagnosis of hypertrophic cardiomyopathy and to evaluate the clinical and morphological diversity of this process consisting of a spectrum of abnormalities with a variable presence in each case. Disproportionate septal hypertrophy is the most frecuent finding but the hypertrophy can involve other segments and different patterns can be present; concentric hypertrophy, apical, involving right ventricle, inverted asymetric, etc. Anterior mitral valve motion can be produced by the interrelation between anatomic factors of the valve, geometry of the outflow tract and physical forces produced by flow changes. Doppler echocardiography allows us to evaluate subaortic obstruction, to define its site, to demonstrate and measure the degree of mitral regurgitation and to carry out intraoperative studies. In hypertrophy cardiomyopathy the pattern of delayed relaxation is the most frequent but patients with severe obstruction and mitral regurgitation can pseudonormalize this pattern and even show restrictive patterns.
- Published
- 1996
81. [Doppler echocardiography in the evaluation of valvular regurgitations].
- Author
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Asín Cardiel E and Moya Mur JL
- Subjects
- Aortic Valve Insufficiency diagnostic imaging, Diagnosis, Differential, Echocardiography, Doppler, Color, Echocardiography, Transesophageal, Humans, Mitral Valve Insufficiency diagnostic imaging, Models, Cardiovascular, Tricuspid Valve Insufficiency diagnostic imaging, Echocardiography, Doppler methods, Heart Valve Diseases diagnostic imaging
- Published
- 1994
82. [Hypertrophic obstructive myocardiopathy complicated by severe mitral insufficiency secondary to rupture of the chordae tendineae].
- Author
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Moya Mur JL, Barjau C, García Lledó A, Asín Cardiel E, de Pablo Zarzosa C, Ortiz de Salazar A, García Andrade I, and Oliva E
- Subjects
- Cardiomyopathy, Hypertrophic diagnosis, Cardiomyopathy, Hypertrophic therapy, Chronic Disease, Combined Modality Therapy, Heart Rupture diagnosis, Heart Rupture surgery, Heart Valve Prosthesis, Humans, Male, Middle Aged, Mitral Valve, Mitral Valve Insufficiency diagnosis, Mitral Valve Insufficiency surgery, Cardiomyopathy, Hypertrophic complications, Chordae Tendineae, Heart Rupture complications, Mitral Valve Insufficiency etiology
- Abstract
A case of suddenly increasing dyspnea in a patient with hypertrophic obstructive cardiomyopathy is reported. Transesophageal echocardiography showed severe mitral regurgitation secondary to ruptured chordae tendineae. Mitral valve replacement was done, correcting both mitral regurgitation and subaortic gradient. Utility of transesophageal echocardiography in diagnosis and therapeutic options are discussed.
- Published
- 1993
83. [Rupture of the intraventricular septum and free wall of the left ventricle secondary to non-penetrating thoracic injury. Doppler echocardiography diagnosis].
- Author
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Jiménez Mena M, Moya Mur JL, Martínez Martínez J, Asin Cardiel E, Barrios Alonso V, Hernández Madrid A, and Epeldegui A
- Subjects
- Adult, Echocardiography, Doppler, Heart Injuries etiology, Heart Septum diagnostic imaging, Heart Ventricles diagnostic imaging, Humans, Male, Heart Injuries diagnostic imaging, Heart Septum injuries, Heart Ventricles injuries, Wounds, Nonpenetrating complications
- Abstract
The heart is often injured in the setting of blunt chest trauma with a broad spectrum of cardiac lesions. We present a twenty-nine years old man with interventricular septal and rupture and left ventricular free wall rupture following chest trauma. Doppler echocardiography was essential in the diagnostic and therapeutic procedure. We concluded that Doppler-echocardiography must be performed in all patients with suspicion of cardiac affectation after blunt chest trauma.
- Published
- 1991
84. [Doppler echocardiography in physiologic valvular insufficiencies].
- Author
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Asín Cardiel E, Jiménez Mena M, Moya Mur JL, and Flores JC
- Subjects
- Aortic Valve Insufficiency diagnostic imaging, Heart Valve Diseases physiopathology, Heart Valves physiopathology, Humans, Mitral Valve Insufficiency diagnostic imaging, Pulmonary Valve Insufficiency diagnostic imaging, Tricuspid Valve Insufficiency diagnostic imaging, Echocardiography, Doppler, Heart Valve Diseases diagnostic imaging, Heart Valves diagnostic imaging
- Published
- 1991
85. [Prognostic significance of silent ischemia in the exercise test in patients with coronary disease].
- Author
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Marín Huerta E, Moya Mur JL, de Pablo C, Rayo I, Muela A, Martín de Dios R, and Moro C
- Subjects
- Adult, Aged, Angina Pectoris diagnosis, Angina Pectoris physiopathology, Coronary Disease etiology, Coronary Disease physiopathology, Cross-Sectional Studies, Female, Follow-Up Studies, Humans, Male, Middle Aged, Prognosis, Coronary Disease diagnosis, Exercise Test
- Abstract
To evaluate the prognostic significance of silent ischemia during exercise testing, 152 consecutive patients (143 males, 9 females) with a mean SD of 55 +/- 7 years (age range 32-73) who underwent exercise testing and coronary arteriography within 3 months were studied. All patients had the following characteristics: 1) a positive electrocardiographic exercise test response; 2) significant coronary artery disease on the arteriography; 3) uninterrupted clinical follow-up for a minimum of 6 months. The 152 patients were divided in 2 groups: group I: 56 patients (37%) with ischemic ST-segment depression during exercise testing without angina (silent ischemia); group II: 96 patients (63%) with ischemic ST-segment depression and angina (symptomatic ischemia). Patients in group I and group II showed similar time to ST-segment depression (3.6 +/- 1.5 min vs 3.2 +/- 1.4 min; p = NS), maximal ST-segment depression and peak heart rate-systolic pressure product (21,151 +/- 7,124 vs 20,456 +/- 6,024; p = NS). Exercise duration was longer in group I than in group II (5.6 +/- 2.1 min vs 4.8 +/- 1.5 min; p less than 0.001). The extent of coronary artery disease defined by the number of significant narrowed coronary vessels, left ventricular end diastolic pressure and ejection fraction were similar in the 2 groups. Sixty six patients who underwent coronary bypass surgery were not included in the analysis. The remaining 86 patients (40 in group I and 46 in group II) were medically treated. The mean follow-up period was 43,5 +/- 25 months (range 6-101).2+ myocardial ischemia during exercise testing.
- Published
- 1990
86. Severe pulmonary arterial hypertension due to toxic oil syndrome: a new cause of plexogenic arteriopathy.
- Author
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Mestre de Juan MJ, Martinez Tello FJ, Gomez Pajuelo C, Saenz de la Calzada C, Moya Mur JL, Tascon Perez JC, Lombera Romero F, and Gomez Sanchez MA
- Subjects
- Fatty Acids, Monounsaturated, Humans, Hypertension, Pulmonary pathology, Muscle, Smooth, Vascular pathology, Pulmonary Artery drug effects, Pulmonary Veins drug effects, Rapeseed Oil, Respiratory Distress Syndrome pathology, Syndrome, Fibromuscular Dysplasia chemically induced, Hypertension, Pulmonary chemically induced, Muscle, Smooth, Vascular drug effects, Plant Oils adverse effects, Respiratory Distress Syndrome chemically induced
- Abstract
Ten patients with severe pulmonary hypertension due to Toxic Oil Syndrome (TOS) (3 men, 7 women; mean age 27.9 +/- 11.23 yrs.) are presented. The pulmonary vessels were examined with a micromorphometric technique. All patients had intimal fibrosis of the arteries and veins. Seven also had a thrombus in different stages. All arteries were shown to have medial hypertrophy. Plexiform lexions were found in eight cases. It is concluded that TOS can produce severe pulmonary hypertension histologically undistinguishable from the primary form. TOS can be added to the list of diseases causing plexogenic arteriopathy.
- Published
- 1990
87. [Psoriatic arthritis associated with severe aortic insufficiency and complete auriculoventricular blockage].
- Author
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Sánchez Sánchez M, Moya Mur JL, Brito Brito E, Morales Piga A, and Morales Durán MD
- Subjects
- Humans, Male, Middle Aged, Aortic Valve Insufficiency complications, Arthritis, Psoriatic complications, Heart Block complications
- Abstract
We report on a case of long lasting psoriatic arthritis HLA B27 positive, complicated by the presence of severe aortic regurgitation and complete atrioventricular block, which required valve replacement and a permanent pacemaker. Valvular tissue histopathological analysis showed changes similar to those found in other seronegative spondyloarthritis.
- Published
- 1989
88. [Traumatic rupture of the aorta presenting as aortic coarctation syndrome].
- Author
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Moya Mur JL, Barrios Alonso V, Fraj Lazaro J, Sánchez Sánchez M, de Pablo Zarzosa C, and Rayo Llerena I
- Subjects
- Adult, Aorta, Abdominal, Humans, Male, Syndrome, Aortic Coarctation etiology, Aortic Rupture complications
- Abstract
Aortic rupture is a frequent cause of death in chest trauma. The coincidence with other associated severe lesions and the absence of clear cardiographic signs may induce to an important delay in the diagnosis. We report a case in which the late apparition of arterial hypertension expressed as an acute aortic coarctation syndrome pointed out the diagnosis. We review the pathogenic mechanisms of arterial hypertension in traumatic aortic rupture and the utility of different diagnostic procedures.
- Published
- 1989
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