465 results on '"Michelakis, Evangelos D."'
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52. Reversing the Warburg Effect: Metabolic Modulation as a Novel Cancer Therapy
53. A Central Role for Oxygen-Sensitive K+ Channels and Mitochondria in the Specialized Oxygen-Sensing System
54. Chapter 5 A Mitochondria-AOS-Kv Channel Axis in Health and Disease; New Insights and Therapeutic Targets for Vascular Disease and Cancer
55. The Role of Doppler Echocardiography in Pulmonary Artery Hypertension: The Importance of Proving the Obvious
56. p53‐Mediated Repression of the PGC1A (PPARG Coactivator 1α) and APLNR (Apelin Receptor) Signaling Pathways Limits Fatty Acid Oxidation Energetics: Implications for Cardio‐oncology
57. Interaction with p53 explains a pro-proliferative function for VHL in cancer
58. A Comprehensive Model for O2 Constriction in the Human Ductus Arteriosus
59. Phosphodiesterase Inhibitors for Pulmonary Hypertension
60. SNPs for Genes Encoding the Mitochondrial Proteins Sirtuin3 and Uncoupling Protein 2 Are Associated With Disease Severity, Type 2 Diabetes, and Outcomes in Patients With Pulmonary Arterial Hypertension and This Is Recapitulated in a New Mouse Model Lacking Both Genes.
61. Gene therapy targeting survivin selectively induces pulmonary vascular apoptosis and reverses pulmonary arterial hypertension
62. Hypoxic pulmonary vasoconstriction: redox regulation of O 2-sensitive K + channels by a mitochondrial O 2-sensor in resistance artery smooth muscle cells
63. Measurement of Nitric Oxide and Nitric Oxide Synthase Activity
64. Use of Sildenafil for Safe Improvement of Erectile Function and Quality of Life in Men With New York Heart Association Classes II and III Congestive Heart Failure: A Prospective, Placebo-Controlled, Double-blind Crossover Trial
65. O2 sensing in the human ductus arteriosus: redox-sensitive K+ channels are regulated by mitochondria-derived hydrogen peroxide
66. Anorectic Drugs and Pulmonary Hypertension from the Bedside to the Bench
67. A dynamic and chamber-specific mitochondrial remodeling in right ventricular hypertrophy can be therapeutically targeted
68. The time has come to pull renal cancer’s sweet tooth
69. A Role for Potassium Channels in Smooth Muscle Cells and Platelets in the Etiology of Primary Pulmonary Hypertension*
70. Pulmonary Vasoconstriction, Oxygen Sensing, and the Role of Ion Channels*: Thomas A. Neff Lecture
71. Mitochondrial HSP90 Accumulation Promotes Vascular Remodeling in Pulmonary Arterial Hypertension
72. A Phase-2 NIH-sponsored Randomized Clinical Trial of Rituximab in Scleroderma-associated Pulmonary Arterial Hypertension Did Not Reach Significance for Its Endpoints: End of Story? Not So Fast!
73. Oxygen Sensing in the Pulmonary Circulation
74. Enhancing Insights into Pulmonary Vascular Disease through a Precision Medicine Approach. A Joint NHLBI–Cardiovascular Medical Research and Education Fund Workshop Report
75. An Official American Thoracic Society Workshop Report: Obesity and Metabolism. An Emerging Frontier in Lung Health and Disease
76. A Paradigm Shift Is Needed in the Field of Pulmonary Arterial Hypertension for Its Entrance Into the Precision Medicine Era
77. Downregulation of microRNA-126 contributes to the failing right ventricle in pulmonary arterial hypertension
78. Potassium channels regulate tone in rat pulmonary veins
79. Metabolic control of epigenetics in cancer
80. Metabolic Enzymes Moonlighting in the Nucleus: Metabolic Regulation of Gene Transcription
81. Metabolic Modulation of Clear-cell Renal Cell Carcinoma with Dichloroacetate, an Inhibitor of Pyruvate Dehydrogenase Kinase
82. Downregulation of microRNA-126 contributes to the failing right ventricle in pulmonary arterial hypertension
83. Mitochondrial HSP90 Accumulation Promotes Vascular Remodeling in Pulmonary Arterial Hypertension.
84. Abstract 19353: Prohibitin: A Potential Circulating Mitokine That May be Involved in Pulmonary Arterial Hypertension
85. Abstract 19386: The Mitochondrial Deacetylase Sirtuin 3 (sirt3) is Important in the Pathogenesis of Both Pulmonary Hypertension and Pulmonary Fibrosis: Potential for an “Overlap Syndrome” and a Common Therapy?
86. Downregulation of MicroRNA-126 Contributes to the Failing Right Ventricle in Pulmonary Arterial Hypertension
87. Addressing Complexity in Pulmonary Hypertension
88. A miR-208–Mef2 Axis Drives the Decompensation of Right Ventricular Function in Pulmonary Hypertension
89. Mitochondrial Diversity in the Vasculature: Implications for Vascular Oxygen Sensing
90. Regulation of O2-Sensitive K+ Channels by a Mitochondrial Redox Sensor: Implications for Hypoxic Pulmonary Vasoconstriction
91. The Role of the NO Axis and its Therapeutic Implications in Pulmonary Arterial Hypertension
92. The Measurement of NO in Biological Systems Using Chemiluminescence
93. Primary Pulmonary Hypertension
94. A Nuclear Pyruvate Dehydrogenase Complex Is Important for the Generation of Acetyl-CoA and Histone Acetylation
95. The Metabolic Theory of Pulmonary Arterial Hypertension
96. Pulmonary Arterial Hypertension
97. Response to Lazarus
98. Exogenous Hydrogen Sulfide (H2S) Protects Alveolar Growth in Experimental O2-Induced Neonatal Lung Injury
99. Role for DNA Damage Signaling in Pulmonary Arterial Hypertension
100. Abstract 18991: A Mir-208-mef2 Axis Drives the Decompensation of Right Ventricular Function in Pulmonary Hypertension
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