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59. Treatment of Small Renal Masses

Author

Schostak, M., Wendler, J. J., Baumunk, D., Blana, A., Ganzer, R., Franiel, T., Hadaschik, B., Henkel, T., Köhrmann, K. U., Köllermann, J., Kuru, T., Machtens, S., Roosen, A., Salomon, G., Schlemmer, H. P., Sentker, L., Witzsch, U., Liehr, U. B., Kramer, Mario W., Section editor, Merseburger, Axel S., Section editor, Merseburger, Axel S., editor, and Burger, Maximilian, editor

Published
2019
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62. Molecular Heterogeneity of Renal Cell Carcinoma

Author

Hou, Weibin, Hoefflin, Rouven, Grüllich, Carsten, Hohenfellner, Markus, Duensing, Stefan, Kramer, Mario W., Section editor, Merseburger, Axel S., Section editor, Merseburger, Axel S., editor, and Burger, Maximilian, editor

Published
2019
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70. Klinik

Author

Hupe, Marie C., Kramer, Mario W., Merseburger, Axel S., Perner, Sven, editor, and Sailer, Verena-Wilbeth, editor

Published
2020
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74. Surveillance of non‐muscle‐invasive bladder cancer with blue‐light cystoscopy: a meta‐analysis.

Author

Sari Motlagh, Reza, Ghoreifi, Alireza, Yanagisawa, Takafumi, Kawada, Tatsushi, Ahyai, Sascha, Merseburger, Axel S., Abufaraj, Mohammad, Abern, Michael, Djaladat, Hooman, Daneshmand, Siamak, and Shariat, Shahrokh F.

Subjects
CANCER relapse, CARCINOMA in situ, PATIENT selection, CYSTOSCOPY, DISEASE relapse, ODDS ratio, BLADDER cancer
Abstract

Objective: To compare the value of flexible blue‐light cystoscopy (BLC) vs flexible white‐light cystoscopy (WLC) in the surveillance setting of non‐muscle‐invasive bladder cancer (NMIBC). Methods: All major databases were searched for articles published before May 2023 according to the Preferred Reporting Items for Systematic Reviews and Meta‐Analyses (PRISMA) statement. The primary outcome was the accuracy of flexible BLC vs WLC in detecting bladder cancer recurrence among suspicious bladder lesions. Results: A total of 10 articles, comprising 1634 patients, were deemed eligible for the quantitative synthesis. In the meta‐analysis focusing on the detection of disease recurrence, there was no difference between flexible BLC and WLC (odds ratio [OR] 1.08, 95% confidence interval [CI] 0.82–1.41)]; the risk difference (RD) showed 1% of flexible BLC, corresponding to a number needed to treat (NNT) of 100. In the subgroup meta‐analysis of detection of carcinoma in situ (CIS) only, there was again no significant difference between flexible BLC and WLC (OR 1.19, 95% CI 0.82–1.69), BLC was associated with a RD of 2% (NNT = 50). The positive predictive values for flexible BLC and WLC in detecting all types of recurrence were 72% and 66%, respectively, and for CIS they were 39% and 29%, respectively. Conclusion: Surveillance of NMIBC with flexible BLC could detect more suspicious lesions and consequently more tumour recurrences compared to flexible WLC, with a increase in the rate of false positives leading to overtreatment. A total of 100 and 50 flexible BLC procedures would need to be performed to find on additional tumor and CIS recurences, respectively. A risk‐stratified strategy for patient selection could be considered when using flexible BLC for the surveillance of NMIBC patients. [ABSTRACT FROM AUTHOR]

Published
2024
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76. Apalutamide plus androgen deprivation therapy in clinical subgroups of patients with metastatic castration-sensitive prostate cancer: a subgroup analysis of the randomised clinical TITAN study

Author

Merseburger, A. S., primary, Agarwal, N., additional, Bhaumik, A., additional, Lefresne, F., additional, Karsh, L. I., additional, Pereira de Santana Gomes, A. J., additional, Juárez Soto, Á., additional, Given, R. W., additional, Brookman-May, S. D., additional, Mundle, S. D., additional, McCarthy, S. A., additional, Uemura, H., additional, Chowdhury, S., additional, Chi, K. N., additional, and Bjartell, A., additional

Published
2024
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77. MP14-08 REAL-WORD CLINICAL CHARACTERIZATION OF METASTATIC HORMONE SENSITIVE PROSTATE CANCER: DATA FROM THE EUROPEAN NETWORK OF EXCELLENCE FOR BIG DATA IN PROSTATE CANCER (PIONEER)

Author

Nicoletti, Rossella, primary, Rivas, Juan Gomez, additional, Ibáñez, Laura, additional, Steinbeisserc, Carl, additional, de Meulder, Bertrand, additional, France, Lyon, additional, Golozar, Asieh, additional, Axelsson, Susan Evans, additional, Snijder, Robert, additional, Bjartell, Anders, additional, Cornford, Philip, additional, Van Hemelrijck, Mieke, additional, Beyer, Katharina, additional, Willemse, Peter-Paul, additional, Murtola, Teemu, additional, Robool, Monique J., additional, Sierra, Jesus Moreno, additional, Campi, Riccardo, additional, Gacci, Mauro, additional, Mottet, Nicolas, additional, Merseburger, Axel, additional, and Ndow, James, additional

Published
2024
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79. MP14-09 DEVELOPMENT OF A PREDICTION MODEL OF SURVIVAL AMONGST PATIENTS WITH METASTATIC HORMONE SENSITIVE PROSTATE CANCER (MHSPC) USING BIG DATA: INTERIM RESULTS FROM THE EUROPEAN NETWORK OF EXCELLENCE FOR BIG DATA IN PROSTATE CANCER (PIONEER)

Author

Nicoletti, Rossella, primary, Rivas, Juan Gomez, additional, Ibáñez, Laura, additional, Steinbeisserc, Carl, additional, de Meulder, Bertrand, additional, Golozar, Asieh, additional, Axelsson, Susan Evans, additional, Snijder, Robert, additional, Bjartell, Anders, additional, Cornford, Philip, additional, Van Hemelrijck, Mieke, additional, Beyer, Katharina, additional, Willemse, Peter-Paul, additional, Murtola, Teemu, additional, Robool, Monique J., additional, Sierra, Jesus Moreno, additional, Campi, Riccardo, additional, Gacci, Mauro, additional, Mottet, Nicolas, additional, Merseburger, Axel, additional, Ndow, James, additional, and Nicoletti, Rossella, additional

Published
2024
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81. Effects of hyperthermia on cisplatin tissue penetration and gene expression in peritoneal metastases: results from a randomized trial in ovarian cancer

Author

Demuytere, Jesse, primary, Carlier, Charlotte, additional, Van Helden, Tom, additional, Belza, Joke, additional, Vanhaecke, Frank, additional, Xie, Feifan, additional, Vermeulen, An, additional, Weerts, Joseph, additional, Thomale, Jürgen, additional, Denys, Hannelore, additional, Tummers, Philippe, additional, Van Kerschaver, Olivier, additional, Willaert, Wouter, additional, Cosyns, Sarah, additional, Merseburger, Peter, additional, Claeys, Arne, additional, Van den Eynden, Jimmy, additional, and Ceelen, Wim, additional

Published
2024
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82. Breaking boundaries: Exploring extended pembrolizumab in first-line treatment of renal cell carcinoma with axitinib-pembrolizumab combination

Author

Aydogdu, C., primary, Paffenholz, P., additional, Stelmach, R., additional, Schlack, K., additional, Roghmann, F., additional, Handke, A., additional, Mandal, S., additional, Schnabel, M., additional, Merseburger, A., additional, Ivanyi, P., additional, Tschäbitz, S., additional, Darr, C., additional, Grünwald, V., additional, Stief, C.G., additional, and Casuscelli, J., additional

Published
2024
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83. SunRISe-3: TAR-200 plus cetrelimab or TAR-200 versus intravesical Bacillus Calmette–Guérin in patients with BCG-naive high-risk non–muscle-invasive bladder cancer

Author

Catto, J.W.F., primary, Necchi, A., additional, Powles, T., additional, Guerrero-Ramos, F., additional, Simone, G., additional, Shore, N., additional, Salinas, J.S., additional, Merseburger, A.S., additional, Roumiguie, M., additional, Hiroshi, K., additional, Morris, D.M., additional, Qiang, W., additional, Korkes, F., additional, Hasan, M., additional, Jin, S., additional, Maffeo, J., additional, Hammond, C., additional, Sweiti, H., additional, Somer, R.S., additional, and Chang, S.S., additional

Published
2024
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84. Development of a predictive model for death amongst patients with Metastatic Hormone Sensitive Prostate Cancer (mHSPC) treated with one of the approved treatment plans, on characteristics present at admission using Big data: Preliminary results from the European network of excellence for big data in prostate cancer (PIONEER)

Author

Nicoletti, R., primary, Gomez Rivas, J., additional, Ibánez, L., additional, Steinbeisse, C., additional, de Meulder, B., additional, Ayman, H., additional, Golozar, A., additional, Snijder, R., additional, Van Hemelrijck, M., additional, Beyer, K., additional, Willemse, P-P., additional, Murtola, T., additional, Roobol, M.J., additional, Moreno-Sierra, J., additional, Campi, R., additional, Gacci, M., additional, Mottet, N., additional, Merseburger, A., additional, Cornford, P., additional, and Ndow, J., additional

Published
2024
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85. Clinical recommendations in the management of advanced prostate cancer: International Gastrointestinal, Liver and Uro-oncology (IGILUC 2019) experts

Author

Elghazaly, Hesham, Mottet, Nicolas, Garcia, Jorge, Oudard, Stephane, Roach, Mack, Abbou, Claude, Merseburger, Axel, Emara, Amr, Shehata, Samir, Tawfik, Hesham, Khorshid, Ola, Selim, Ahmed, Assem, Akram, Abdelkarim, Khalid, Ezz El-Arab, Lobna, Bazarbashi, Shouki, Omar, Abbass, Elwakil, Hesham, Elashry, Mohamed, Abou ElFotouh, Mohamed, Osman, Tarek, and Ezz El Din, Mai

Published
2021
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88. COCONUT online: Collection of Open Natural Products database

Author

Maria Sorokina, Peter Merseburger, Kohulan Rajan, Mehmet Aziz Yirik, and Christoph Steinbeck

Subjects
Natural products, Database, NoSQL, MongoDB, Molecular similarity search, Molecular substructure search, Information technology, T58.5-58.64, Chemistry, QD1-999
Abstract

Abstract Natural products (NPs) are small molecules produced by living organisms with potential applications in pharmacology and other industries as many of them are bioactive. This potential raised great interest in NP research around the world and in different application fields, therefore, over the years a multiplication of generalistic and thematic NP databases has been observed. However, there is, at this moment, no online resource regrouping all known NPs in just one place, which would greatly simplify NPs research and allow computational screening and other in silico applications. In this manuscript we present the online version of the COlleCtion of Open Natural prodUcTs (COCONUT): an aggregated dataset of elucidated and predicted NPs collected from open sources and a web interface to browse, search and easily and quickly download NPs. COCONUT web is freely available at https://coconut.naturalproducts.net .

Published
2021
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90. Management of Sporadic Renal Angiomyolipomas: A Systematic Review of Available Evidence to Guide Recommendations from the European Association of Urology Renal Cell Carcinoma Guidelines Panel

Author

Fernández-Pello, Sergio, Hora, Milan, Kuusk, Teele, Tahbaz, Rana, Dabestani, Saeed, Abu-Ghanem, Yasmin, Albiges, Laurence, Giles, Rachel H., Hofmann, Fabian, Kuczyk, Markus A., Lam, Thomas B., Marconi, Lorenzo, Merseburger, Axel S., Powles, Thomas, Staehler, Michael, Volpe, Alessandro, Ljungberg, Börje, Bex, Axel, and Bensalah, Karim

Published
2020
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93. Forschungsaktivitäten zum Peniskarzinom in Deutschland und Österreich - eine Fragebogenstudie unter Lehrstuhlinhabern mit ergänzender Literaturrecherche und bibliometrischer Analyse

Author

May, M, Wolff, I, Lusuardi, L, Kravchuk, A, Wiegland, J, Yakac, A, Thomas, C, Burger, M, Bründl, J, Lebentrau, S, Ahyai, S, Merseburger, A, Gilfrich, C, May, M, Wolff, I, Lusuardi, L, Kravchuk, A, Wiegland, J, Yakac, A, Thomas, C, Burger, M, Bründl, J, Lebentrau, S, Ahyai, S, Merseburger, A, and Gilfrich, C

Published
2024

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