51. Burden of Peripheral Artery Disease on Mortality and Incident Cardiovascular Events
- Author
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Unkart, Jonathan T, Allison, Matthew A, Araneta, Maria Rosario G, Ix, Joachim H, Matsushita, Kunihiro, and Criqui, Michael H
- Subjects
Public Health ,Health Sciences ,Heart Disease ,Cardiovascular ,Minority Health ,Aging ,Atherosclerosis ,Good Health and Well Being ,Aged ,Aged ,80 and over ,Ankle Brachial Index ,Cardiovascular Diseases ,Female ,Humans ,Incidence ,Male ,Middle Aged ,Peripheral Arterial Disease ,Risk Assessment ,Risk Factors ,Surveys and Questionnaires ,United States ,ankle brachial index ,claudication ,multivessel ,primary prevention ,screening ,Mathematical Sciences ,Medical and Health Sciences ,Epidemiology - Abstract
Using data from the Multi-Ethnic Study of Atherosclerosis (United States, 2000-2015), 6,527 racially/ethnically diverse adults (mean age, 62 (standard deviation, 10) years) free of known cardiovascular (CVD) had ankle brachial index (ABI) assessment of their bilateral dorsalis pedis/posterior tibial arteries (4 vessels total) and were followed for total mortality and incident CVD events/mortality. Individuals were classified into categories of 0-, 1-, 2-, 3- or 4-vessel peripheral artery disease (PAD) (ABI of ≤0.9). There were 1,202 deaths (18%), 656 incident CVD events (10%), and 282 CVD deaths (4.3%). Of the 6,527 individuals, 5,711 (87.5%) had 0-, 460 (7.0%) had 1-, 218 (3.3%) had 2-, 69 (1.1%) had 3-, and 69 (1.1%) had 4-vessel PAD, respectively. In multivariable Cox models, higher number of vessels with PAD was associated with higher risk of mortality (P for trend
- Published
- 2020