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1,103 results on '"Mariuca"'

52. Coronary Artery Disease Assessment via On-Site CT Fractional Flow Reserve in Patients Undergoing Transcatheter Aortic Valve Replacement

Author

Steyer, Alexandra, primary, Puntmann, Valentina O., additional, Nagel, Eike, additional, Leistner, David M., additional, Koch, Vitali, additional, Vasa-Nicotera, Mariuca, additional, Kumar, Parveen, additional, Booz, Christian, additional, Vogl, Thomas J., additional, Mas-Peiro, Silvia, additional, and Martin, Simon S., additional

Published
2024
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53. Towards Automated Android App Collusion Detection

Author

Asavoae, Irina Mariuca, Blasco, Jorge, Chen, Thomas M., Kalutarage, Harsha Kumara, Muttik, Igor, Nguyen, Hoang Nga, Roggenbach, Markus, and Shaikh, Siraj Ahmed

Subjects
Computer Science - Software Engineering, Computer Science - Cryptography and Security
Abstract

Android OS supports multiple communication methods between apps. This opens the possibility to carry out threats in a collaborative fashion, c.f. the Soundcomber example from 2011. In this paper we provide a concise definition of collusion and report on a number of automated detection approaches, developed in co-operation with Intel Security.

Published
2016

59. A streamlined pathway for transcatheter aortic valve implantation: the BENCHMARK study.

Author

Frank, Derk, Durand, Eric, Lauck, Sandra, Muir, Douglas F, Spence, Mark, Vasa-Nicotera, Mariuca, Wood, David, Saia, Francesco, Urbano-Carrillo, Cristóbal A, Bouchayer, Damien, Iliescu, Vlad Anton, Saint Etienne, Christophe, Leclercq, Florence, Auffret, Vincent, Asmarats, Lluis, Di Mario, Carlo, Veugeois, Aurelie, Maly, Jiri, Schober, Andreas, and Nombela-Franco, Luis

Subjects
HEART valve prosthesis implantation, CORONARY care units, TRANSIENT ischemic attack, INTERMEDIATE care, INTENSIVE care units, LENGTH of stay in hospitals
Abstract

Background and Aims: There is significant potential to streamline the clinical pathway for patients undergoing transcatheter aortic valve implantation (TAVI). The purpose of this study was to evaluate the effect of implementing BENCHMARK best practices on the efficiency and safety of TAVI in 28 sites in 7 European countries. Methods: This was a study of patients with severe symptomatic aortic stenosis (AS) undergoing TAVI with balloon-expandable valves before and after implementation of BENCHMARK best practices. Principal objectives were to reduce hospital length of stay (LoS) and duration of intensive care stay. Secondary objective was to document patient safety. Results: Between January 2020 and March 2023, 897 patients were documented prior to and 1491 patients after the implementation of BENCHMARK practices. Patient characteristics were consistent with a known older TAVI population and only minor differences. Mean LoS was reduced from 7.7 ± 7.0 to 5.8 ± 5.6 days (median 6 vs. 4 days; P <.001). Duration of intensive care was reduced from 1.8 to 1.3 days (median 1.1 vs. 0.9 days; P <.001). Adoption of peri-procedure best practices led to increased use of local anaesthesia (96.1% vs. 84.3%; P <.001) and decreased procedure (median 47 vs. 60 min; P <.001) and intervention times (85 vs. 95 min; P <.001). Thirty-day patient safety did not appear to be compromised with no differences in all-cause mortality (0.6% in both groups combined), stroke/transient ischaemic attack (1.4%), life-threatening bleeding (1.3%), stage 2/3 acute kidney injury (0.7%), and valve-related readmission (1.2%). Conclusions: Broad implementation of BENCHMARK practices contributes to improving efficiency of TAVI pathway reducing LoS and costs without compromising patient safety. Structured Graphical Abstract BENCHMARK: streamlined transcatheter aortic valve implantation (TAVI) pathway with retained safety. CCU, coronary care unit; ICU, intensive care unit; GW, general ward; IMC, intermediate care; PPM, permanent pacemaker. *Includes patients with available data on LoS only. [ABSTRACT FROM AUTHOR]

Published
2024
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63. BENCHMARK: Impact of Different Health Care Systems on the Implementation of a Streamlined Patient Pathway Across Five European Countries

Author

Saia, Francesco, primary, Lauck, Sandra, additional, Durand, Eric, additional, Muir, Douglas F., additional, Spence, Mark, additional, Nicotera, Mariuca Vasa, additional, Wood, David, additional, Urbano-Carrillo, Cristóbal A., additional, Bouchayer, Damien, additional, Iliescu, Vlad Anton, additional, Saint Etienne, Christophe, additional, Leclercq, Florence, additional, Auffret, Vincent, additional, Asmarats, Lluis, additional, Mario, Carlo Di, additional, Veugeois, Aurelie, additional, Maly, Jiri, additional, Schober, Andreas, additional, Nombela-Franco, Luis, additional, Werner, Nikos, additional, Gómez-Hospital, Joan Antoni, additional, Mascherbauer, Julia, additional, McCalmont, Gemma, additional, Rakova, Radka, additional, Wesselink, Wilbert, additional, Kurucova, Jana, additional, Hachaturyan, Violetta, additional, Lüske, Claudia M., additional, Bramlage, Peter, additional, Frank, Derk, additional, and Group, BENCHMARK Investigator, additional

Published
2024
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65. Determination of the Fermi Level Position in Dilute Magnetic Ga$_{1-x}$Mn$_{x}$N Films

Author

Barthel, Stefan, Kunert, Gerd, Gartner, Mariuca, Stoica, Mihai, Mourad, Daniel, Kruse, Carsten, Figge, Stephan, Hommel, Detlef, and Czycholl, Gerd

Subjects
Condensed Matter - Materials Science, Condensed Matter - Disordered Systems and Neural Networks
Abstract

We report on a combined theoretical and experimental determination of the Fermi level position in wurtzite Ga$_{1-x}$Mn$_{x}$N films with $x=4\%$ and $x=10\%$ as grown by molecular beam epitaxy. By means of ellipsometric measurements the real part of the frequency-dependent conductivity is determined. An electronic model in the framework of the effective bond-orbital model is parameterized in order to theoretically reproduce the measured transport properties. Predictions for the long-wavelength behaviour as a function of the Fermi level are made. The corresponding density of states obtained in this model is in qualitative agreement with first-principle calculations. The absence of a significant experimental peak in the AC conductivity for small frequencies indicates that the Fermi level lies in a gap between two Mn-related impurity bands in the host band gap.

Published
2014
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70. Context-Updates Analysis and Refinement in Chisel

Author

Asăvoae, Irina Măriuca, Asăvoae, Mihail, Riesco, Adrián, Hutchison, David, Series Editor, Kanade, Takeo, Series Editor, Kittler, Josef, Series Editor, Kleinberg, Jon M., Series Editor, Mattern, Friedemann, Series Editor, Mitchell, John C., Series Editor, Naor, Moni, Series Editor, Pandu Rangan, C., Series Editor, Steffen, Bernhard, Series Editor, Terzopoulos, Demetri, Series Editor, Tygar, Doug, Series Editor, Weikum, Gerhard, Series Editor, Gallardo, María del Mar, editor, and Merino, Pedro, editor

Published
2018
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71. Software Model Checking for Mobile Security – Collusion Detection in

Author

Asăvoae, Irina Măriuca, Nguyen, Hoang Nga, Roggenbach, Markus, Hutchison, David, Series Editor, Kanade, Takeo, Series Editor, Kittler, Josef, Series Editor, Kleinberg, Jon M., Series Editor, Mattern, Friedemann, Series Editor, Mitchell, John C., Series Editor, Naor, Moni, Series Editor, Pandu Rangan, C., Series Editor, Steffen, Bernhard, Series Editor, Terzopoulos, Demetri, Series Editor, Tygar, Doug, Series Editor, Weikum, Gerhard, Series Editor, Gallardo, María del Mar, editor, and Merino, Pedro, editor

Published
2018
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72. Interacting via the Heap in the Presence of Recursion

Author

Rot, Jurriaan, Asăvoae, Irina Măriuca, de Boer, Frank, Bonsangue, Marcello M., and Lucanu, Dorel

Subjects
Computer Science - Programming Languages, Computer Science - Logic in Computer Science, F.1.1, F.1.2, F.3.1, F.3.3
Abstract

Almost all modern imperative programming languages include operations for dynamically manipulating the heap, for example by allocating and deallocating objects, and by updating reference fields. In the presence of recursive procedures and local variables the interactions of a program with the heap can become rather complex, as an unbounded number of objects can be allocated either on the call stack using local variables, or, anonymously, on the heap using reference fields. As such a static analysis is, in general, undecidable. In this paper we study the verification of recursive programs with unbounded allocation of objects, in a simple imperative language for heap manipulation. We present an improved semantics for this language, using an abstraction that is precise. For any program with a bounded visible heap, meaning that the number of objects reachable from variables at any point of execution is bounded, this abstraction is a finitary representation of its behaviour, even though an unbounded number of objects can appear in the state. As a consequence, for such programs model checking is decidable. Finally we introduce a specification language for temporal properties of the heap, and discuss model checking these properties against heap-manipulating programs., Comment: In Proceedings ICE 2012, arXiv:1212.3458

Published
2012
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73. Band gap bowing of binary alloys: Experimental results compared to theoretical tight-binding supercell calculations for CdZnSe

Author

Mourad, Daniel, Kruse, Carsten, Klembt, Sebastian, Retzlaff, Reiner, Gartner, Mariuca, Anastasescu, Mihai, Hommel, Detlef, and Czycholl, Gerd

Subjects
Condensed Matter - Materials Science, Physics - Computational Physics
Abstract

Compound semiconductor alloys of the type ABC find widespread applications as their electronic bulk band gap varies continuously with x, and therefore a tayloring of the energy gap is possible by variation of the concentration. We model the electronic properties of such semiconductor alloys by a multiband tight-binding model on a finite ensemble of supercells and determine the band gap of the alloy. This treatment allows for an intrinsic reproduction of band bowing effects as a function of the concentration x and is exact in the alloy-induced disorder. In the present paper, we concentrate on bulk CdZnSe as a well-defined model system and give a careful analysis on the proper choice of the basis set and supercell size, as well as on the necessary number of realizations. The results are compared to experimental results obtained from ellipsometric measurements of CdZnSe layers prepared by molecular beam epitaxy (MBE) and photoluminescence (PL) measurements on catalytically grown CdZnSe nanowires reported in the literature., Comment: 7 pages, 6 figures

Published
2010
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75. Sol-Gel Multilayered Niobium (Vanadium)-Doped TiO 2 for CO Sensing and Photocatalytic Degradation of Methylene Blue.

Author

Simeonov, Simeon, Szekeres, Anna, Covei, Maria, Stroescu, Hermine, Nicolescu, Madalina, Chesler, Paul, Hornoiu, Cristian, and Gartner, Mariuca

Subjects
CARBON monoxide detectors, METHYLENE blue, CARBON dioxide, NIOBIUM, TITANIUM dioxide, ELECTRIC capacity, PHOTODEGRADATION, ELECTRON density
Abstract

Multilayered TiO2 films doped either with Niobium or Vanadium (1.2 at. %) were deposited by the sol-gel dip coating method on c-Si and glass substrates. The films on glass substrates were tested for CO sensing and photocatalytic degradation of methylene blue. X-ray diffraction data analysis showed that all the TiO2:Nb(V) films were nanocrystalline in the anatase phase, with a uniform and compact microstructure and a homogeneous superficial structure of small grains with diameters in the range of 13–19 nm. For the electrical characterization, the TiO2:Nb(V) films were incorporated in Metal-Insulator-Semiconductor (MIS) structures. The specific resistivity is of the order of 104 Ωcm and its value decreases with increasing the electrical field, which testifies to the injection of electrons into these layers. From the analysis of the current–voltage curves taken at different temperature- and frequency—dependent capacitance–voltage and conductance–voltage characteristics, the density and parameters of deep levels in these TiO2 films are evaluated and the electron charge transport mechanism is established. It was shown that the current in these TiO2:Nb(V)-Si MIS structures is mainly carried out by inter-trap tunneling via deep levels energetically distributed in the TiO2 bandgap. Testing these sol-gel TiO2:Nb(V) layers for gas sensing and photocatalytic capabilities proved that they could serve such purposes. In particular, the results of the V-doped sol-gel TiO2 film confirm its CO detection capability, which is rarely reported in the literature. For the photodegradation of methylene blue, the Nb-doped TiO2 samples were superior, with nearly double the photocatalytic efficiency of undoped TiO2. [ABSTRACT FROM AUTHOR]

Published
2024
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77. Valve Hemodynamics by Valve Size and 1-Year Survival Following Implantation of the Portico Valve in the Multicenter CONFIDENCE Registry

Author

Möllmann, Helge, primary, Linke, Axel, additional, Nombela-Franco, Luis, additional, Sluka, Martin, additional, Francisco Oteo Dominguez, Juan, additional, Montorfano, Matteo, additional, Kim, Won-Keun, additional, Arnold, Martin, additional, Vasa-Nicotera, Mariuca, additional, Fichtlscherer, Stephan, additional, Conradi, Lenard, additional, Camuglia, Anthony, additional, Bedogni, Francesco, additional, Kohli, Keshav, additional, and Manoharan, Ganesh, additional

Published
2023
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78. Recent Developments in Engineering Research Vol. 1

Author

Kumar, Kamalesh, additional, Vivek, Gada, additional, Kharade, K. G., additional, Kharade, S. K., additional, Kumbhar, V. S., additional, Kamat, R. K., additional, Oliveira, Raquel Salomé, additional, Marques, António Torres, additional, Simões, José, additional, Torres, Cláudio, additional, Annadurai, A., additional, Elakkiah, C., additional, Gopikrishnan, V., additional, Vignesh, A., additional, Manigundan, K., additional, Radhakrishnan, M., additional, Joseph, Jerrine, additional, Suglo, Raymond S., additional, Frimpong, Samuel, additional, Brown, Osei Frimpong, additional, Zaharescu, Maria, additional, Mihaiu, Susana, additional, Vladut, Cristina Maria, additional, Tenea, Ecaterina, additional, Preda, Silviu, additional, Calderόn-Moreno, José María, additional, Anastasescu, Mihai, additional, Stroescu, Hermine, additional, Atkinson, Irina, additional, Apostol, Nicoleta, additional, Moldovan, Carmen, additional, Gartner, Mariuca, additional, Thirumalai, R., additional, Gobinath, S., additional, Babu, S. Suresh, additional, Dwivedi, Yagya Dutta, additional, Sakly, Houneida, additional, Said, Mourad, additional, Tagina, Moncef, additional, Ekambaram, Rajasekaran, additional, Rajasekaran, Indupriya, additional, Reddy, T. Srinivas, additional, Rodríguez-Martínez, Juan M., additional, Rossello, Eduardo A., additional, López, Arquímedes Cruz, additional, León, Lilia E. Arriaga-Díaz de, additional, Bermúdez-Cerda, Javier Eugenio, additional, V., Priya, additional, and Kumar, M. C. Sampath, additional

Published
2020
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81. Slicing from Formal Semantics: Chisel

Author

Riesco, Adrián, Asăvoae, Irina Măriuca, Asăvoae, Mihail, Hutchison, David, Series editor, Kanade, Takeo, Series editor, Kittler, Josef, Series editor, Kleinberg, Jon M., Series editor, Mattern, Friedemann, Series editor, Mitchell, John C., Series editor, Naor, Moni, Series editor, Pandu Rangan, C., Series editor, Steffen, Bernhard, Series editor, Terzopoulos, Demetri, Series editor, Tygar, Doug, Series editor, Weikum, Gerhard, Series editor, Huisman, Marieke, editor, and Rubin, Julia, editor

Published
2017
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83. Surgical site infection after gastrointestinal surgery in high-income, middle-income, and low-income countries: a prospective, international, multicentre cohort study

Author

Bhangu, Aneel, Ademuyiwa, Adesoji O, Aguilera, Maria Lorena, Alexander, Philip, Al-Saqqa, Sara W, Borda-Luque, Giuliano, Costas-Chavarri, Ainhoa, Drake, Thomas M, Ntirenganya, Faustin, Fitzgerald, J Edward, Fergusson, Stuart J, Glasbey, James, Ingabire, JC Allen, Ismaïl, Lawani, Salem, Hosni Khairy, Kojo, Anyomih Theophilus Teddy, Lapitan, Marie Carmela, Lilford, Richard, Mihaljevic, Andre L, Morton, Dion, Mutabazi, Alphonse Zeta, Nepogodiev, Dmitri, Adisa, Adewale O, Ots, Riinu, Pata, Francesco, Pinkney, Thomas, Poškus, Tomas, Qureshi, Ahmad Uzair, Ramos-De la Medina, Antonio, Rayne, Sarah, Shaw, Catherine A, Shu, Sebastian, Spence, Richard, Smart, Neil, Tabiri, Stephen, Harrison, Ewen M, Khatri, Chetan, Mohan, Midhun, Jaffry, Zahra, Altamini, Afnan, Kirby, Andrew, Søreide, Kjetil, Recinos, Gustavo, Cornick, Jen, Modolo, Maria Marta, Iyer, Dushyant, King, Sebastian, Arthur, Tom, Nahar, Sayeda Nazmum, Waterman, Ade, Walsh, Michael, Agarwal, Arnav, Zani, Augusto, Firdouse, Mohammed, Rouse, Tyler, Liu, Qinyang, Correa, Juan Camilo, Talving, Peep, Worku, Mengistu, Arnaud, Alexis, Kalles, Vassilis, Kumar, Basant, Kumar, Sunil, Amandito, Radhian, Quek, Roy, Ansaloni, Luca, Altibi, Ahmed, Venskutonis, Donatas, Zilinskas, Justas, Poskus, Tomas, Whitaker, John, Msosa, Vanessa, Tew, Yong Yong, Farrugia, Alexia, Borg, Elaine, Bentounsi, Zineb, Gala, Tanzeela, Al-Slaibi, Ibrahim, Tahboub, Haya, Alser, Osaid H, Romani, Diego, Shu, Sebestian, Major, Piotr, Mironescu, Aurel, Bratu, Matei, Kourdouli, Amar, Ndajiwo, Aliyu, Altwijri, Abdulaziz, Alsaggaf, Mohammed Ubaid, Gudal, Ahmad, Jubran, Al Faifi, Seisay, Sam, Lieske, Bettina, Ortega, Irene, Jeyakumar, Jenifa, Senanayake, Kithsiri J, Abdulbagi, Omar, Cengiz, Yucel, Raptis, Dmitri, Altinel, Yuksel, Kong, Chia, Teasdale, Ella, Irwin, Gareth, Stoddart, Michael, Kabariti, Rakan, Suresh, Sukrit, Gash, Katherine, Narayanan, Ragavan, Maimbo, Mayaba, Grizhja, Besmir, Ymeri, Shpetim, Galiqi, Gezim, Klappenbach, Roberto, Antezana, Diego, Mendoza Beleño, Alvaro Enrique, Costa, Cecilia, Sanchez, Belen, Aviles, Susan, Fermani, Claudio Gabriel, Balmaceda, Rubén, Villalobos, Santiago, Carmona, Juan Manuel, Hamill, Daniel, Deutschmann, Peter, Sandler, Simone, Cox, Daniel, Nataraja, Ram, Sharpin, Claire, Ljuhar, Damir, Gray, Demi, Haines, Morgan, Iyer, Dush, Niranjan, Nithya, D'Amours, Scott, Ashtari, Morvarid, Franco, Helena, Rahman Mitul, Ashrarur, Karim, Sabbir, Aman, Nowrin F, Estee, Mahnuma Mahfuz, Salma, Umme, Razzaque, Joyeta, Hamid Kanta, Tasnia, Tori, Sayeeda Aktar, Alamin, Shadid, Roy, Swapnil, Al Amin, Shadid, Karim, Rezaul, Haque, Muhtarima, Faruq, Amreen, Iftekhar, Farhana, O'Shea, Margaret, Padmore, Greg, Jonnalagadda, Ramesh, Litvin, Andrey, Filatau, Aliaksandr, Paulouski, Dzmitry, Shubianok, Maryna, Shachykava, Tatsiana, Khokha, Dzianis, Khokha, Vladimir, Djivoh, Fernande, Dossou, Francis, Seto, Djifid Morel, Gbessi, Dansou Gaspard, Noukpozounkou, Bruno, Imorou Souaibou, Yacoubou, Keke, Kpèmahouton René, Hodonou, Fred, Ahounou, Ernest Yemalin Stephane, Alihonou, Thierry, Dénakpo, Max, Ahlonsou, Germain, Ginbo Bedada, Alemayehu, Nsengiyumva, Carlos, Kwizera, Sandrine, Barendegere, Venerand, Choi, Philip, Stock, Simon, Jamal, Luai, Azzie, Georges, Kushwaha, Sameer, Chen, Tzu-Ling, Yip, Chingwan, Montes, Irene, Zapata, Felipe, Sierra, Sebastian, Villegas Lanau, Maria Isabel, Mendoza Arango, Maria Clara, Mendoza Restrepo, Ivan, Restrepo Giraldo, Ruben Santiago, Domini, Edgar, Karlo, Robert, Mihanovic, Jakov, Youssef, Mohamed, Elfeki, Hossam, Thabet, Waleed, Sanad, Aly, Tawfik, Gehad, Zaki, Ahmed, Abdel-Hameed, Noran, Mostafa, Mohamed, Omar, Muhammad Fathi Waleed, Ghanem, Ahmed, Abdallah, Emad, Denewer, Adel, Emara, Eman, Rashad, Eman, Sakr, Ahmad, Elashry, Rehab, Emile, Sameh, Khafagy, Toqa, Elhamouly, Sara, Elfarargy, Arwa, Mamdouh Mohamed, Amna, Saied Nagy, Ghada, Esam, Abeer, Elwy, Eman, Hammad, Aya, Khallaf, Salwa, Ibrahim, Eman, Said Badr, Ahmed, Moustafa, Ahmed, Eldosouky Mohammed, Amany, Elgheriany, Mohammed, Abdelmageed, Eman, Al Raouf, Eman Abd, Samir Elbanby, Esraa, Elmasry, Maha, Morsy Farahat, Mahitab, Yahya Mansor, Eman, Magdy Hegazy, Eman, Gamal, Esraa, Gamal, Heba, Kandil, Hend, Maher Abdelrouf, Doaa, Moaty, Mohamed, Gamal, Dina, El-Sagheer, Nada, Salah, Mohamed, Magdy, Salma, Salah, Asmaa, Essam, Ahmed, Ali, Ahmed, Badawy, Mahmoud, Ahmed, Sara, Mohamed, Mazed, Assal, Abdelrahman, Sleem, Mohamed, Ebidy, Mai, Abd-Elrazek, Aly, Zahran, Diaaaldin, Adam, Nourhan, Nazir, Mohamed, Hassanein, Adel B, Ismail, Ahmed, Elsawy, Amira, Mamdouh, Rana, Mabrouk, Mohamed, Ahmed, Lopna Ahmed Mohamed, Hassab Alnaby, Mohamed, Magdy, Eman, Abd-Elmawla, Manar, Fahim, Marwan, Mowafy, Bassant, Ibrahim Mahmoud, Moustafa, Allam, Meran, Alkelani, Muhammad, Halim El Gendy, Noran, Saad Aboul-Naga, Mariam, Alaa El-Din, Reham, Elgendy, Alyaa Halim, Ismail, Mohamed, Shalaby, Mahmoud, Adel Elsharkawy, Aya, Elsayed Moghazy, Mahmoud, Hesham Elbisomy, Khaled, Abdel Gawad Shakshouk, Hend, Hamed, Mohamed Fouad, Ebidy, Mai Mohamed, Abdelkader, Mostafa, Karkeet, Mohamed, Ahmed, Hayam, Adel, Israa, Omar, Mohammad Elsayed, Ibrahim, Mohamed, Ghoneim, Omar, Hesham, Omar, Gamal, Shimaa, Hilal, Karim, Arafa, Omar, Adel Awad, Sawsan, Salem, Menatalla, Abdellatif Elsherif, Fawzia, Elsabbagh, Nourhan, Aboelsoud, Moustafa R, Hossam Eldin Fouad Rida, Ahmed, Hossameldin, Amr, Hany, Ethar, Hosny Asar, Yomna, Anwar, Nourhan, Gadelkarim, Mohamed, Abdelhady, Samar, Mohamed Morshedy, Eman, Saad, Reham, Soliman, Nourhan, Salama, Mahmoud, Ezzat, Eslam, Mohamed, Arwa, Ibrahim, Arwa, Fergany, Alaa, Mohammed, Sara, Reda, Aya, Allam, Yomna, Saad, Hanan Adel, Abdelfatah, Afnan, Fathy, Aya Mohamed, El-Sehily, Ahmed, Abdalmageed Kasem, Esraa, Hassan, Ahmed Tarek Abdelbaset, Mohammed, Ahmed Rabeih, Saad, Abdalla Gamal, Elfouly, Yasmin, Elfouly, Nesma, Ibrahim, Arij, Hassaan, Amr, Mohammed, Mohammed Mustafa, Elhoseny, Ghada, Magdy, Mohamed, Abd Elkhalek, Esraa, Zakaria, Yehia, Ezzat, Tarek, Abo El Dahab, Ali, Kelany, Mohamed, Arafa, Sara, Mokhtar Mohamed Hassan, Osama, Mohamed Badwi, Nermin, Saber Sleem, Ahmad, Ahmed, Hussien, Abdelbadeai, Kholoud, Abozed Abdullah, Mohamed, Lokman, Muhammad Amsyar Auni, Bahar, Suraya, Rady Abdelazeam, Anan, Adelshone, Abdelrahman, Bin Hasnan, Muhammad, Zulkifli, Athirah, Kamarulzamil, Siti Nur Alia, Elhendawy, Abdelaziz, Latif, Aliang, Bin Adnan, Ahmad, Shaharuddin, Shahadatul, Haji Abdul Majid, Aminah Hanum, Amreia, Mahmoud, Al-Marakby, Dina, Salma, Mahmoud, Ismail, Mohamad Jeffrey Bin, Mohd Basir, Elissa Rifhan, Mohd Ali, Citra Dewi, Ata, Aya Yehia, Nasr, Maha, Rezq, Asmaa, Sheta, Ahmed, Tariq, Sherif, Sallam, Abd Elkhalek, Darwish, Abdelrhman KZ, Elmihy, Sohaila, Elhadry, Shady, Farag, Ahmed, Hajeh, Haidar, Abdelaal, Abdelaziz, Aglan, Amro, Zohair, Ahmed, Essam, Mahitab, Moussa, Omar, El-Gizawy, Esraa, Samy, Mostafa, Ali, Safia, El Halawany, Esraa, Ata, Ahmed, El Halawany, Mohamed, Nashat, Mohamed, Soliman, Samar, Elazab, Alaa, Samy, Mostada, Abdelaziz, Mohamed A, Ibrahim, Khaled, Ibrahim, Ahmed Mohamed, Gado, Ammar, Hantour, Usama, Alm Eldeen, Esraa, Loaloa, Mohamed Reda, Abouzaid, Arwa, Ahmed Bahaa Eldin, Mostafa, Hashad, Eman, Sroor, Fathy, Gamil, Doaa, Mahmoud Abdulhakeem, Eman, Zakaria, Mahmoud, Mohamed, Fawzy, Abubakr, Marwan, Ali, Elsayed, Magdy, Hesham, Ramadan, Menna Tallah, Abdelaty Mohamed, Mohamed, Mansour, Salma, Abdul Aziz Amin, Hager, Rabie Mohamed, Ahmed, Saami, Mahmoud, Ahmed Reda Elsayed, Nada, Tarek, Adham, Mohy Eldeen Mahmoud, Sabry, Magdy El Sayed, Islam, Reda, Amira, Yusuf Shawky, Martina, Mousa Salem, Mohammed, Alaa El-Din, Shahinaz, Abdullah Soliman, Noha, Talaat, Muhammed, Alaael-Dein, Shahinaz, Abd Elmoen Elhusseiny, Ahmed, Abdullah, Noha, Elshaar, Mohammed, Abdelfatah Ibraheem, Aya, Abdulaziz, Hager, Kamal Ismail, Mohammed, Hamdy Madkor, Mona, Abdelaty, Mohamed, Mahmoud Abdel-Kader, Sara, Mohamed Salah, Osama, Eldafrawy, Mahmoud, Zaki Eldeeb, Ahmed, Mahmoud Eid, Mostafa, Attia, Attia, Salah El-Dien, Khalid, Shwky, Ayman, Badenjki, Mohamed Adel, Soliman, Abdelrahman, Mahmoud Al Attar, Samaa, Sayed, Farrag, Abdel Sabour, Fahd, Azizeldine, Mohammed G, Shawqi, Muhammad, Hashim, Abdullah, Aamer, Ahmed, Abdelraouf, Ahmed Mahmoud, Abdelshakour, Mahmoud, Ibrahim, Amal, Mahmoud, Basma, Ali Mahmoud, Mohamed, Qenawy, Mostafa, Rashed, Ahmed M, Dahy, Ahmed, Sayed, Marwa, Shamsedine, Ahmed W, Mohamed, Bakeer, Hasan, Ahmad, Saad, Mahmoud M, Abdul Bassit, Khalil, Khalid Abd El-Latif, Nadia, Elzahed, Nada, El Kashash, Ahmed, Bekhet, Nada Mohamed, Hafez, Sarah, Gad, Ahmed, Maher, Mahmoud Elkhadragy, Abd El-Sameea, Ahmed, Hafez, Mohamed, Sabe, Ahmad, Ahmed, Ataa, Shahine, Ahmed, Dawood, Khaled, Gaafar, Shireen, Husseiny, Reem, Aboelmagd, Omnia, Soliman, Ahmed, Mesbah, Nourhan, Emadeldin, Hossam, Al Meligy, Amgad, Bekhet, Amira Hassan, Hasan, Doaa, Alhady, Khaled, Sabe, Ahmad Khaled, Elnajjar, Mahmoud A, Aboelella, Majed, Hamsho, Ward, Hassan, Ihab, Saad, Hala, Abdelazim, 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Nouh, Thamer, Khan, Roaa, Radojkovic, Milan, Jeremic, Ljiljana, Nestorovic, Milica, Law, Jia Hao, Tan, Keith Say Kwang, Tan, Ryan Choon Kiat, Tan, Joel Kin, Joel, Lau Wen Liang, Chan, Xue Wei, Leong, Faith Qi Hui, Chong, Choon Seng, Koh, Sharon, Lee, Kai Yin, Lee, Kuok Chung, Pluke, Kent, Dedekind, Britta, Nashidengo, Puyearashid, Hampton, Mark Ian, Joosten, Johanna, Sobnach, Sanju, Roodt, Liana, Sander, Anthony, Pape, James, Maistry, Niveshni, Ndwambi, Phumudzo, Kinandu, Kamau, Tun, Myint, Du Toit, Frederick, Ellison, Quinn, Burger, Sule, Grobler, DC, Khulu, Lawrence Bongani, Moore, Rachel, Jennings, Vicky, Leusink, Astrid, Kariem, Nazmie, Gouws, Juan, Chu, Kathryn, Bougard, Heather, Noor, Fazlin, Dell, Angela, Van Straten, Stephanie, Khamajeet, Arvin, Tshisola, Serge Kapenda, Kabongo, Kalangu, Kong, Victor, Moodley, Yoshan, Anderson, Frank, Madiba, Thandinkosi, du Plooy, Flip, Hartford, Leila, Chilton, Gareth, Karjiker, Parveen, Mabitsela, Matlou Ernest, Ndlovu, Sibongile Ruth, Badicel, Maria, Jaich, Robert, Ruiz-Tovar, Jaime, Garcia-Florez, Luis, Otero-Díez, Jorge L, Ramos Pérez, Virginia, Aguado Suárez, Nuria, Minguez García, Javier, Corral Moreno, Sara, Collado, Maria Vicenta, Jiménez Carneros, Virginia, García Septiem, Javier, Gonzalez, Mariana, Picardo, Antonio, Esteban, Enrique, Ferrero, Esther, Espin-Basany, Eloy, Blanco-Colino, Ruth, Andriola, Valeria, Solar García, Lorena, Contreras, Elisa, García Bernardo, Carmen, Pagnozzi, Janet, Sanz, Sandra, Miyar de León, Alberto, Dorismé, Asnel, Rodicio, Joseluis, Suarez, Aida, Stuva, Jessica, Diaz Vico, Tamara, Fernandez-Vega, Laura, Soldevila-Verdeguer, Carla, Sena-Ruiz, Fatima, Pujol-Cano, Natalia, Diaz-Jover, Paula, Garcia-Perez, José Maria, Segura-Sampedro, Juan Jose, Pineño-Flores, Cristina, Ambrona-Zafra, David, Craus-Miguel, Andrea, Jimenez-Morillas, Patricia, Mazzella, Angela, Jayathilake, AB, Thalgaspitiya, SPB, Wijayarathna, LS, Wimalge, PMSN, Sanni, Hakeem Ayomi, Okenabirhie, Ogheneochuko, Homeida, Anmar, Younis, Abobaker, Omer, Omer Abdelbagi, Abdulaziz, Mustafa, Mussad, Ali, Adam, Ali, Björklund, Ida, Ahlqvist, Sandra, Thorell, Anders, Wogensen, Fredrik, Sokratous, Arestis, Breistrand, Michaela, Thorarinsdottir, Hildur, Sigurdadottir, Johanna, Nikberg, Maziar, Chabok, Abbas, Hjertberg, Maria, Elbe, Peter, Saraste, Deborah, Rutkowski, Wiktor, Forlin, Louise, Niska, Karoliina, Sund, Malin, Oswald, Dennis, Peros, Georgios, Bluelle, Rafael, Reinisch, Katharina, Frey, Daniel, Palma, Adrian, Raptis, Dimitri Aristotle, Zumbühl, Lucius, Zuber, Markus, Schmid, Roger, Werder, Gabriela, Nocito, Antonio, Gerosa, Alexandra, Mahanty, Silke, Widmer, Lukas Werner, Müller, Julia, Gübeli, Alissa, Zuk, Grzegorz, Gulcicek, Osman Bilgin, Vartanoglu, Talar, Kose, Emin, Karahan, Servet Rustu, Aydin, Mehmet Can, Sahbaz, Nuri Alper, Halicioglu, Ilkay, Alis, Halil, Sapci, Ipek, Adiyaman, Can, Pektaş, Ahmet Murat, Cengiz, Turgut Bora, Tansoker, Ilkan, Işler, Vedatcan, Cevik, Muazzez, Mutlu, Deniz, Ozben, Volkan, Ozmen, Berk Baris, Bayram, Sefa, Yolcu, Sinem, Kobal, Berna Buse, Toto, Ömer Faruk, Çakaloğlu, Haluk Cem, Karabulut, Kagan, Mutlu, Vahit, Ozkan, Bahar Busra, Celik, Saban, Semiz, Anil, Bodur, Selim, Gül, Enisburak, Murutoglu, Busra, Yildirim, Reyyan, Baki, Bahadir Emre, Arslan, Ekin, Ulusahin, Mehmet, Guner, Ali, Tomas, Kudir, Walker, Nathan, Shrimanker, Nikhita, Cole, Simon, Breslin, Ryan, Srinivasan, Ravi, Elshaer, Mohamed, Hunter, Kristina, Al-Bahrani, Ahmed, Liew, Ignatius, Mairs, Nora Grace, Rocke, Alistair, Dick, Lachlan, Qureshi, Mobeen, Chowdhury, Debkumar, Wright, Naomi, Skerritt, Clare, Kufeji, Dorothy, Ho, Adrienne, Dissanayake, Tharindra, Tennakoon, Athula, Ali, Wadah, Lim, Shujing Jane, Tan, Charlene, O'Neill, Stephen, Jones, Catrin, Knight, Stephen, Nassif, Dima, Sharma, Abhishek, Warren, Oliver, White, Rebecca, Mehdi, Aia, Post, Nathan, Kalakouti, Eliana, Dashnyam, Enkhbat, Stourton, Frederick, Mykoniatis, Ioannis, Currow, Chelise, Wong, Francisca, Gupta, Ashish, Shatkar, Veeranna, Luck, Joshua, Kadiwar, Suraj, Smedley, Alexander, Wakefield, Rebecca, Herrod, Philip, Blackwell, James, Lund, Jonathan, Cohen, Fraser, Bandi, Ashwath, Giuliani, Stefano, Bond-Smith, Giles, Pezas, Theodore, Farhangmehr, Neda, Urbonas, Tomas, Perenyei, Miklos, Ireland, Philip, Blencowe, Natalie, Bowling, Kirk, Bunting, David, Longstaff, Lydia, Keogh, Kenneth, Jeon, Hyunjin, Iqbal, Muhammad Rafaih, Khosla, Shivun, Jeffery, Anna, Perera, James, Ibrahem, Ahmad Aboelkassem, Alhammali, Tariq, Salama, Yahya, Oram, Shaun, Kidd, Thomas, Cullen, Fraser, Owen, Christopher, Wilson, Michael, Chiu, Seehui, Sarafilovic, Hannah, Ploski, Jennifer, Evans, Elizabeth, Abbas, Athar, Kamya, Sylvia, Ishak, Norzawani, Bisset, Carly, Andress, Cedar, Chin, Ye Ru, Patel, Priya, Evans, David, Haslegrave, Aidan, Boggon, Adam, Laurie, Kirsten, Connor, Katie, Mann, Thomas, Mansuri, Anahita, Davies, Rachel, Griffiths, Ewen, Shahbaz, Aized Raza, Eng, Calvin, Din, Farhat, L'Heveder, Ariadne, Park, Esther HG, Ravishankar, Ramanish, McIntosh, Kirsten, Yau, Jih Dar, Chan, Luke, McGarvie, Susan, Tang, Lingshan, Lim, Hui, Yap, Suhhuey, Park, Jay, Ng, Zhan Herr, Mirza, Shahrukh, Ang, Yun Lin, Walls, Luke, Roy, Chloe, Paterson-Brown, Simon, Camilleri-Brennan, Julian, Mclean, Kenneth, D'Souza, Michelle S, Pronin, Savva, Henshall, David Ewart, Ter, Eunice Zuling, Fouad, Dina, Minocha, Ashish, English, William, Morgan, Catrin, Townsend, Dominic, Maciejec, Laura, Mahdi, Shareef, Akpenyi, Onyinye, Hall, Elisabeth, Caydiid, Hanaan, Rob, Zakaria, Abbott, Tom, Torrance, Hew D, Johnston, Robin, Gani, Mohammed Aki, Gravante, Gianpiero, Rajmohan, Shivanchan, Majid, Kiran, Dindyal, Shiva, Smith, Christopher, Palliyil, Madanmohan, Patel, Sanjay, Nicholson, Luke, Harvey, Neil, Baillie, Katie, Shillito, Sam, Kershaw, Suzanne, Bamford, Rebecca, Orton, Peter, Reunis, Elke, Tyler, Robert, Soon, Wai Cheong, Jama, Guled M, Dhillon, Dharminder, Patel, Khyati, Nanthakumaran, Shayanthan, Heard, Rachel, Chen, Kar Yan, Barmayehvar, Behrad, Datta, Uttaran, Kamarajah, Sivesh K, Karandikar, Sharad, Iftekhar Tani, Sobhana, Monaghan, Eimear, Donnelly, Philippa, Walker, Michael, Parakh, Jehangirshaw, Blacker, Sarah, Kaul, Anil, Paramasivan, Arjun, Farag, Sameh, Nessa, Ashrafun, Awadallah, Salwa, Lim, Jieqi, Chean Khun Ng, James, Kiran, Ravi P, Murray, Alice, Etchill, Eric, Dasari, Mohini, Puyana, Juan, Haddad, Nadeem, Zielinski, Martin, Choudhry, Asad, Caliman, Celeste, Beamon, Mieshia, Duane, Therese, Swaroop, Mamta, Myers, Jonathan, Deal, Rebecca, Schadde, Erik, Hemmila, Mark, Napolitano, Lena, To, Kathleen, Makupe, Alex, Musowoya, Joseph, van der Naald, Niels, Kumwenda, Dayson, Reece-Smith, Alex, Otten, Kars, Verbeek, Anna, Prins, Marloes, Baquero Suarez, Alibeth Andres, Balmaceda, Ruben, Deane, Chelsea, Dijan, Emilio, Elfiky, Mahmoud, Koskenvuo, Laura, Thollot, Aurore, Limoges, Bernard, Capito, Carmen, Alexandre, Challine, Kotobi, Henri, Leroux, Julien, Pinnagoda, Kalitha, Henric, Nicolas, Azzis, Olivier, Rosello, Olivier, Francois, Poddevin, Etienne, Sara, Buisson, Philippe, Hmila, Sophian, Clegg-Lamptey, Joe-Nat, Imoro, Osman, Abem, Owusu Emmanuel, Papageorgiou, Dimitrios, Soulou, Vasiliki, Asturias, Sabrina, Peña, Lenin, O'Connor, Donal B, Luc, Alberto Realis, Russo, Alfio Alessandro, Ruzzenente, Andrea, Taddei, Antonio, Cona, Camilla, Bottini, Corrado, Pascale, Giovanni, Rotunno, Giuseppe, Solaini, Leonardo, Pascale, Marco Maria, Notarnicola, Margherita, Corbellino, Mario, Sacco, Michele, Ubiali, Paolo, Cautiero, Roberto, Bocchetti, Tommaso, Muzio, Elena, Guglielmo, Vania, Morandi, Eugenio, Mao, Patrizio, de Luca, Emilia, Ali, Farah Mahmoud, Žilinskas, Justas, Strupas, Kestutis, Kondrotas, Paulius, Baltrunas, Robertas, Kutkevicius, Juozas, Ignatavicius, Povilas, Tan, Choy Ling, Siaw, Jia Yng, Yam, Sir Young, Wilson, Ling, Aziz, Mohamed Rezal Abdul, Bondin, John, Zorrilla, Carmina Diaz, Majbar, Anass, Sale, Danjuma, Abdullahi, Lawal, Osagie, Olabisi, Faboya, Omolara, Fatuga, Adedeji, Taiwo, Agboola, Nwabuoku, Emeka, Bliksøen, Marte, Khan, Zain Ali, Coronel, Jazmin, Miranda, Cesar, Vasquez, Idelso, Helguero-Santin, Luis M, Rickard, Jennifer, Adedeji, Adesina, Alqahtani, Saleh, Rath, Max, Van Niekerk, Michael, Koto, Modise Zacharia, Matos-Puig, Roel, Israelsson, Leif, Schuetz, Tobias, Yuksek, Mahmut Arif, Mericliler, Meric, Wolf, Bernhard, Fairfield, Cameron, Yong, Guo Liang, Whitehurst, Katharine, Redgrave, Natalie, Musyoka, Caroluce K, Olivier, James, Lee, Kathryn, Cox, Michael, Farhan-Alanie, Muhamed M H, Callan, Rory, Chibuye, Chali, Ali, Tebian Hassanein Ahmed, Rekhis, Syrine, Rommaneh, Muna, Sam, Zi Hao, Pugliesi, Thays Brunelli, Pardo, Gabriel, and Blanco, Ruth

Published
2018
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85. Long-term risk associated with clonal hematopoiesis in patients with severe aortic valve stenosis undergoing TAVR

Author

Silvia Mas-Peiro, Graziella Pergola, Alexander Berkowitsch, Manja Meggendorfer, Michael A. Rieger, Mariuca Vasa-Nicotera, Stefanie Dimmeler, and Andreas M. Zeiher

Subjects
General Medicine, Cardiology and Cardiovascular Medicine
Abstract

Background Mutations in the clonal hematopoiesis of indeterminate potential (CHIP)-driver genes DNMT3A and TET2 have been previously shown to be associated with short-term prognosis in patients undergoing TAVR for aortic valve stenosis. We aimed to extend and characterize these findings on long-term outcome in a large cohort. Methods A total of 453 consecutive patients undergoing TAVR were included in an up to 4-year follow-up study. Next-generation sequencing was used to identify DNMT3A- and/or TET2-CHIP-driver mutations. Primary endpoint was all-cause mortality. Since CHIP-driver mutations appear to be closely related to DNA methylation, results were also assessed in patients who never smoked, a factor known to interfere with DNA methylation. Results DNMT3A-/TET2-CHIP-driver mutations were present in 32.4% of patients (DNMT3A n = 92, TET2 n = 71), and were more frequent in women (52.4% vs. 38.9%, p = 0.007) and older participants (83.3 vs. 82.2 years, p = 0.011), while clinical characteristics or blood-derived parameters did not differ. CHIP-driver mutations were associated with a significantly higher mortality up to 4 years after TAVR in both univariate (p = 0.031) and multivariate analyses (HR 1.429, 95%CI 1.014–2.013, p = 0.041). The difference was even more pronounced (p = 0.011) in never smokers. Compared to TET2 mutation carriers, patients with DNMT3A mutations had significantly less frequently concomitant coronary and peripheral artery disease. Conclusion DNMT3A- and TET2-CHIP-driver mutations are associated with long-term mortality in patients with aortic valve stenosis even after a successful TAVR. The association is also present in never smokers, in whom no biasing effect from smoking on DNA methylation is to be expected. Graphical Abstract

Published
2023

86. The effect of postprandial in vivo and experimental in vitro hyperlipidemia on human peripheral blood monocytes

Author

Ion Bogdan Manescu, Mariuca Manescu, Elena Cristina Preda, Doina Ramona Manu, and Minodora Dobreanu

Subjects
General Pharmacology, Toxicology and Pharmaceutics, General Dentistry
Abstract

Objective: In this study, we aimed to investigate the effect of transient postprandial in vivo and prolonged experimental in vitro hyperlipidemia on human peripheral blood monocytes. Methods: Peripheral blood was collected from seven healthy subjects after an overnight fast and three hours after a standardized high-fat meal. Both fasting and postprandial samples were stained for surface markers CD14/CD11b and intracellular lipids using BODIPY493/503. Postprandial samples only were used for isolation of peripheral blood mononuclear cells that were further incubated overnight with postprandial hyperlipidemic autologous plasma, then stained as described above. All samples were analyzed on a FACSAria III flow cytometer. Results: Flow cytometric analysis revealed two monocyte populations (CD14+): CD14low and CD14high. In fasting, these populations show similar morphology (FSC/SSC), but different expressions of CD14, CD11b, and BODIPY493/503. At three hours postprandially, a moment of maximum hyperlipidemia, neither population suffered significant changes. After the 24-hour incubation, cell activation was observed in both populations: similar fold change increase in SSC, increase in FSC for CD14high cells only, similar foldchange increase in CD14, slightly higher foldchange increase in CD11b for CD14low monocytes, and significantly higher foldchange increase in lipid content for CD14high monocytes. CD14high monocytes appear to undergo a more intense activation than CD14low monocytes. Conclusions: We conclude that all monocytes react after prolonged in vitro exposure to plasma lipids, each subset having its own activation pattern. All monocyte types may play a role in inflammation and the development of plaques. Monocyte assays are a valuable tool for the investigation of atherosclerosis at the cellular level.

Published
2022

87. A scoring system for predicting malignancy in intraductal papillary mucinous neoplasms of the pancreas

Author

Alba, Manuel-Vázquez, Anita, Balakrishnan, Paul, Agami, Bodil, Andersson, Frederik, Berrevoet, Marc G, Besselink, Ugo, Boggi, Damiano, Caputo, Alberto, Carabias, Lucia, Carrion-Alvarez, Carmen Cepeda, Franco, Alessandro, Coppola, Bobby V M, Dasari, Sherley, Diaz-Mercedes, Michail, Feretis, Constantino, Fondevila, Giuseppe Kito, Fusai, Giuseppe, Garcea, Victor, Gonzabay, Miguel Ángel Gómez, Bravo, Myrte, Gorris, Bart, Hendrikx, Camila, Hidalgo-Salinas, Prashant, Kadam, Dimitrios, Karavias, Emanuele, Kauffmann, Amar, Kourdouli, Vincenzo, La Vaccara, Stijn, van Laarhoven, James, Leighton, Mike S L, Liem, Nikolaos, Machairas, Dimitris, Magouliotis, Adel, Mahmoud, Marco V, Marino, Marco, Massani, Paola Melgar, Requena, Keno, Mentor, Niccolò, Napoli, Jorieke H T, Nijhuis, Andrej, Nikov, Cristina, Nistri, Victor, Nunes, Eduardo Ortiz, Ruiz, Sanjay, Pandanaboyana, Baltasar Pérez, Saborido, Radek, Pohnán, Mariuca, Popa, Belinda Sánchez, Pérez, Francisco Sánchez, Bueno, Alejandro, Serrablo, Mario, Serradilla-Martín, James R A, Skipworth, Kjetil, Soreide, Dimitris, Symeonidis, Dimitris, Zacharoulis, Piotr, Zelga, Daniel, Aliseda, María Jesús Castro, Santiago, Carlos Fernández, Mancilla, Raquel Latorre, Fragua, Daniel Llwyd, Hughes, Carmen Payá, Llorente, Mickaël, Lesurtel, Tom, Gallagher, José Manuel, Ramia, Surgery, CCA - Cancer Treatment and Quality of Life, CCA - Imaging and biomarkers, AGEM - Amsterdam Gastroenterology Endocrinology Metabolism, Gastroenterology and Hepatology, and Graduate School

Subjects
Intraductal papillary mucinous neoplasm, Pancreatic Intraductal Neoplasms, Score, Malignancy, Preoperative diagnosis, Adenocarcinoma, Mucinous, intraductal papillary mucinous neoplasm, malignancy, pancreatic neoplasm, preoperative diagnosis, score, Pancreatic Neoplasms, Humans, Surgery, Pancreatic neoplasm, Pancreas, Carcinoma, Pancreatic Ductal, Retrospective Studies
Abstract

Purpose A preoperative estimate of the risk of malignancy for intraductal papillary mucinous neoplasms (IPMN) is important. The present study carries out an external validation of the Shin score in a European multicenter cohort. Methods An observational multicenter European study from 2010 to 2015. All consecutive patients undergoing surgery for IPMN at 35 hospitals with histological-confirmed IPMN were included. Results A total of 567 patients were included. The score was significantly associated with the presence of malignancy (p < 0.001). In all, 64% of the patients with benign IPMN had a Shin score < 3 and 57% of those with a diagnosis of malignancy had a score >= 3. The relative risk (RR) with a Shin score of 3 was 1.37 (95% CI: 1.07-1.77), with a sensitivity of 57.1% and specificity of 64.4%. Conclusion Patients with a Shin score

Published
2022

88. Abstract P3070: Aortic Valve Calcification Is Accelerated By DNMT3A And TET2 Gene Driver Mutations Associated With Clonal Hematopoiesis

Author

Abplanalp, Wesley T, primary, Schuhmacher, Bianca, additional, Mas-Peiro, Silvia, additional, Zuriaga, Maria A, additional, Matesanz, Nuria, additional, Fuster, Jose J, additional, John, David, additional, Muhly-Reinholz, Marion, additional, Vasa-Nicotera, Mariuca, additional, Merten, Maximilian, additional, Dimmeler, Stefanie, additional, and Zeiher, Andreas M, additional

Published
2023
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90. Comparison of Self-Expanding Bioprostheses for Transcatheter Aortic Valve Replacement in Patients With Symptomatic Severe Aortic Stenosis: SCOPE 2 Randomized Clinical Trial

Author

Tamburino, Corrado, Bleiziffer, Sabine, Thiele, Holger, Scholtz, Smita, Hildick-Smith, David, Cunnington, Michael, Wolf, Alexander, Barbanti, Marco, Tchetchè, Didier, Garot, Philippe, Pagnotta, Paolo, Gilard, Martine, Bedogni, Francesco, Van Belle, Eric, Vasa-Nicotera, Mariuca, Chieffo, Alaide, Deutsch, Oliver, Kempfert, Jörg, Søndergaard, Lars, Butter, Christian, Trillo-Nouche, Ramiro, Lotfi, Shahram, Möllmann, Helge, Joner, Michael, Abdel-Wahab, Mohamed, Bogaerts, Kris, Hengstenberg, Christian, and Capodanno, Davide

Published
2020
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94. Utilising Semantics for Collusion Detection in Android Applications

Author

Asăvoae, Irina Măriuca, Nguyen, Hoang Nga, Roggenbach, Markus, Shaikh, Siraj, Hutchison, David, Series editor, Kanade, Takeo, Series editor, Kittler, Josef, Series editor, Kleinberg, Jon M., Series editor, Mattern, Friedemann, Series editor, Mitchell, John C., Series editor, Naor, Moni, Series editor, Pandu Rangan, C., Series editor, Steffen, Bernhard, Series editor, Terzopoulos, Demetri, Series editor, Tygar, Doug, Series editor, Weikum, Gerhard, Series editor, ter Beek, Maurice H., editor, Gnesi, Stefania, editor, and Knapp, Alexander, editor

Published
2016
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96. Advanced Nanostructured Coatings Based on Doped TiO 2 for Various Applications.

Author

Gartner, Mariuca, Szekeres, Anna, Stroescu, Hermine, Mitrea, Daiana, and Covei, Maria

Subjects
*TITANIUM dioxide, *WATER disinfection, *SURFACE coatings, *GAS detectors, *WASTEWATER treatment, *ELECTRON transport, *ZINC oxide films
Abstract

For many years, TiO2-based materials and improving their properties in order to expand their application areas have been the focus of numerous research groups. Various innovative approaches have been proposed to improve the photocatalytic and gas-sensing properties of TiO2 nanostructures. In this review, we aim to synthesize the available information in the literature, paying special attention to the sol–gel technology, which is one of the most frequently used methods for TiO2 synthesis. The influence of dopants on the structural, morphological, optical, and electrical properties of TiO2 and the way to modify them in a controlled manner are briefly discussed. The role of shallow and/or deep energy levels within the TiO2 bandgap in the electron transport behavior of doped TiO2 is emphasized. Selected research on photocatalytic applications in water disinfection, wastewater treatment, and self-sterilizing coatings that contribute to improving the quality of human life and environmental preservation is highlighted. A survey of biosensors that are closely related to medical applications such as cancer detection, implantology, and osteogenesis is also provided. Finally, the pressing problems that need to be solved in view of the future development of TiO2-based nanostructures are listed. [ABSTRACT FROM AUTHOR]

Published
2023
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98. Influence of the Deposition Parameters on the Properties of TiO2 Thin Films on Spherical Substrates

Author

Gartner, Maria Covei, Cristina Bogatu, Silvioara Gheorghita, Anca Duta, Hermine Stroescu, Madalina Nicolescu, Jose Maria Calderon-Moreno, Irina Atkinson, Veronica Bratan, and Mariuca

Subjects
TiO2 thin film, photocatalysis, glass bead substrate, sol-gel, dilution ratio, number of layers, morphology, structure, stability
Abstract

Wastewater treatment targeting reuse may limit water scarcity. Photocatalysis is an advanced oxidation process that may be employed in the removal of traces of organic pollutants, where the material choice is important. Titanium dioxide (TiO2) is a highly efficient photocatalyst with good aqueous stability. TiO2 powder has a high surface area, thus allowing good pollutant adsorption, but it is difficult to filter for reuse. Thin films have a significantly lower surface area but are easier to regenerate and reuse. In this paper, we report on obtaining sol-gel TiO2 thin films on spherical beads (2 mm diameter) with high surface area and easy recovery from wastewater. The complex influence of the substrate morphology (etched up to 48 h in concentrated H2SO4), of the sol dilution with ethanol (1:0 or 1:1), and the number of layers (1 or 2) on the structure, morphology, chemical composition, and photocatalytic performance of the TiO2 thin films is investigated. Etching the substrate for 2 h in H2SO4 leads to uniform, smooth surfaces on which crystalline, homogeneous TiO2 thin films are grown. Films deposited using an undiluted sol are stable in water, with some surface reorganization of the TiO2 aggregates occurring, while the films obtained using diluted sol are partially washed out. By increasing the film thickness through the deposition of a second layer, the roughness increases (from ~50 nm to ~100 nm), but this increase is not high enough to promote higher adsorption or overall photocatalytic efficiency in methylene blue photodegradation (both about 40% after 8 h of UV-Vis irradiation at 55 W/m2). The most promising thin film, deposited on spherical bead substrates (etched for 2 h in H2SO4) using the undiluted sol, with one layer, is highly crystalline, uniform, water-stable, and proves to have good photocatalytic activity.

Published
2023
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99. Use of Telemedicine for Post-discharge Assessment of the Surgical Wound. International Cohort Study, and Systematic Review with Meta-analysis

Author

James, Glasbey, Issi, Trout, Victoria, Adeyeye, Adesoji, Ademuyiwa, Adewale, Adisa, Alisha, Bhatt, Bruce, Biccard, Peter, Brocklehurst, Jean De La Croix Allen Ingabire, Francis Moïse Dossou, Irani, Durán, Rohini, Dutta, Dhruva, Ghosh, Frank, Gyamfi, Pollyanna, Hardy, Gabriella, Hyman, Ritu, Jain, Bryar, Kadir, Stephen, Knight, Oluwaseun, Ladipo-Ajayi, Ismail, Lawani, Souliath, Lawani, Rachel, Lillywhite, Rhiannon, Macefield, Laura, Magill, Janet, Martin, Jonathan, Mathers, Kenneth, Mclean, Punam, Mistry, Rohin, Mittal, Rachel, Moore, Dion, Morton, Faustin, Ntirenganya, Emmanuel, Ofori, Rupert, Pearse, Alberto, Peón, Thomas, Pinkney, Antonio Ramos de la Medina, Tubasiime, Ronald, David, Roman, Joana, Simoes, Anita, Slade, Stephen, Tabiri, Donna, Smith, Ewen, Harrison, Aneel, Bhangu, Azmina, Verjee, Emmy, Runigamugabo, Adesoji, O Ademuyiwa, Adewale, O Adisa, Maria Lorena Aguilera, Afnan, Altamini, Philip, Alexander, Sara, W Al-Saqqa, Giuliano, Borda-Luque, Jen, Cornick, Ainhoa, Costas-Chavarri, Thomas, M Drake, Stuart, J Fergusson, J Edward Fitzgerald, C Allen Ingabire, J, Lawani, Ismaïl, Zahra, Jaffry, Hosni Khairy Salem, Chetan, Khatri, Andrew, Kirby, Anyomih Theophilus Teddy Kojo, Marie Carmela Lapitan, Richard, Lilford, Andre, L Mihaljevic, Midhun, Mohan, Alphonse Zeta Mutabazi, Dmitri, Nepogodiev, Riinu, Ots, Pata, Francesco, Tomas, Poškus, Ahmad Uzair Qureshi, Antonio Ramos-De la Medina, Sarah, Rayne, Gustavo, Recinos, Kjetil, Søreide, Catherine, A Shaw, Sebastian, Shu, Richard, Spence, Neil, Smart, Ewen, M Harrison, Maria Marta Modolo, Dushyant, Iyer, Sebastian, King, Tom, Arthur, Sayeda Nazmum Nahar, Ade, Waterman, Michael, Walsh, Arnav, Agarwal, Zani, Augusto, Mohammed, Firdouse, Tyler, Rouse, Qinyang, Liu, Juan Camilo Correa, Peep, Talving, Mengistu, Worku, Alexis, Arnaud, Vassilis, Kalles, Basant, Kumar, Sunil, Kumar, Radhian, Amandito, Roy, Quek, Luca, Ansaloni, Ahmed, Altibi, Donatas, Venskutonis, Justas, Zilinskas, Tomas, Poskus, John, Whitaker, Vanessa, Msosa, Yong Yong Tew, Alexia, Farrugia, Elaine, Borg, Zineb, Bentounsi, Tanzeela, Gala, Ibrahim, Al-Slaibi, Haya, Tahboub, Osaid, H Alser, Diego, Romani, Sebestian, Shu, Piotr, Major, Aurel, Mironescu, Matei, Bratu, Amar, Kourdouli, Aliyu, Ndajiwo, Abdulaziz, Altwijri, Mohammed Ubaid Alsaggaf, Ahmad, Gudal, Al Faifi Jubran, Sam, Seisay, Bettina, Lieske, Irene, Ortega, Jenifa, Jeyakumar, Kithsiri, J Senanayake, Omar, Abdulbagi, Yucel Cengiz Dmitri Raptis, Yuksel, Altinel, Chia, Kong, Ella, Teasdale, Gareth, Irwin, Michael, Stoddart, Rakan, Kabariti, Sukrit, Suresh, Katherine, Gash, Ragavan, Narayanan, Mayaba, Maimbo, Besmir, Grizhja, Shpetim, Ymeri, Gezim, Galiqi, Roberto, Klappenbach, Diego, Antezana, Alvaro Enrique Mendoza Beleño, Cecilia, Costa, Belen, Sanchez, Susan, Aviles, Claudio Gabriel Fermani, Rubén, Balmaceda, Santiago, Villalobos, Juan Manuel Carmona, Daniel, Hamill, Peter, Deutschmann, Simone, Sandler, Daniel, Cox, Ram, Nataraja, Claire, Sharpin, Damir, Ljuhar, 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Alhammali, Tariq, Salama, Yahya, Oram, Shaun, Kidd, Thoma, Cullen, Fraser, Owen, Christopher, Wilson, Michael, Chiu, Seehui, Sarafilovi, Hannah, Ploski, Jennifer, Evans, Elizabeth, Abbas, Athar, Kamya, Sylvia, Ishak, Norzawani, Bisset, Carly, Andress, Cedar, Ru Chin, Ye, Patel, Priya, Evans, David, Haslegrave, Aidan, Boggon, Adam, Laurie, Kirsten, Connor, Katie, Mann, Thoma, Mansuri, Anahita, Davies, Rachel, Griffiths, Ewen, Raza Shahbaz, Aized, Eng, Calvin, Din, Farhat, L'Heveder, Ariadne, G Park, Esther H, Ravishankar, Ramanish, Mcintosh, Kirsten, Dar Yau, Jih, Chan, Luke, Mcgarvie, Susan, Tang, Lingshan, Lim, Hui, Yap, Suhhuey, Park, Jay, Herr Ng, Zhan, Mirza, Shahrukh, Lin Ang, Yun, Walls, Luke, Roy, Chloe, Paterson-Brown, Simon, Camilleri-Brennan, Julian, S D'Souza, Michelle, Pronin, Savva, Ewart Henshall, David, Zuling Ter, Eunice, Fouad, Dina, Minocha, Ashish, English, William, Morgan, Catrin, Townsend, Dominic, Maciejec, Laura, Mahdi, Shareef, Akpenyi, Onyinye, Hall, Elisabeth, 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Paolo, Cautiero, Roberto, Bocchetti, Tommaso, Muzio, Elena, Guglielmo, Vania, Morandi, Eugenio, Mao, Patrizio, De Luca, Emilia, Mahmoud Ali, Farah, Žilinskas, Justa, Strupas, Kestuti, Kondrotas, Pauliu, Baltrunas, Roberta, Kutkevicius, Juoza, Ignatavicius, Povila, Ling Tan, Choy, Yng Siaw, Jia, Young Yam, Sir, Wilson, Ling, Rezal Abdul Aziz, Mohamed, Bondin, John, Diaz Zorrilla, Carmina, Majbar, Ana, Sale, Danjuma, Abdullahi, Lawal, Osagie, Olabisi, Faboya, Omolara, Fatuga, Adedeji, Taiwo, Agboola, Nwabuoku, Emeka, Bliksøen, Marte, Ali Khan, Zain, Coronel, Jazmin, Miranda, Cesar, Vasquez, Idelso, M Helguero-Santin, Lui, Rickard, Jennifer, Adedeji, Adesina, Alqahtani, Saleh, Rath, Max, Van Niekerk, Michael, Zacharia Koto, Modise, Matos-Puig, Roel, Israelsson, Leif, Schuetz, Tobia, Arif Yuksek, Mahmut, Mericliler, Meric, Uluşahi, Mehmet, Wolf, Bernhard, Fairfield, Cameron, Liang Yong, Guo, Whitehurst, Katharine, Redgrave, Natalie, K Musyoka, Caroluce, Olivier, Jame, Lee, Kathryn, Cox, Michael, H Farhan-Alanie, Muhamed M, Callan, Rory, Chibuye, Chali, Hassanein Ahmed Ali, Tebian, Rekhis, Syrine, Rommaneh, Muna, Hao Sam, Zi, Hong Chieh Chen, Jacky, Roi, Dylan, Brunelli Pugliesi, Thay, Pardo, Gabriel, Blanco, Ruth, and Grasset Escobar, Eugenio

Subjects
surgical site infection , surgical complications , global surgery , global health , research methodology , outcome assessment, surgical wound, Surgery, telemedicine, postdischarge
Abstract

Objective: This study aimed to determine whether remote wound reviews using telemedicine can be safely upscaled, and if standardised assessment tools are needed. Summary background data: Surgical site infection is the most common complication of surgery worldwide, and frequently occurs after hospital discharge. Evidence to support implementation of telemedicine during postoperative recovery will be an essential component of pandemic recovery. Methods: The primary outcome of this study was surgical site infection reported up to 30-days after surgery (SSI), comparing rates reported using telemedicine (telephone and/or video assessment) to those with in-person review. The first part of this study analysed primary data from an international cohort study of adult patients undergoing abdominal surgery who were discharged from hospital before 30-days after surgery. The second part combined this data with the results of a systematic review to perform a meta-analysis of all available data conducted in accordance with PRIMSA guidelines (PROSPERO:192596). Results: The cohort study included 15,358 patients from 66 countries (8069 high, 4448 middle, 1744 low income). Of these, 6907 (45.0%) were followed up using telemedicine. The SSI rate reported using telemedicine was slightly lower than with in-person follow-up (13.4% vs. 11.1%, P

Published
2023

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