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3,110 results on '"Man, Mohan"'

53. Mapping development and health effects of cooking with solid fuels in low-income and middle-income countries, 2000–18: a geospatial modelling study

Author

Frostad, Joseph Jon, Nguyen, QuynhAnh P, Baumann, Mathew M, Blacker, Brigette F, Marczak, Laurie B, Deshpande, Aniruddha, Wiens, Kirsten E, LeGrand, Kate E, Johnson, Kimberly B, Abbasi-Kangevari, Mohsen, Abdoli, Amir, Abolhassani, Hassan, Abreu, Lucas Guimarães, Abrigo, Michael R M, Abu-Rmeileh, Niveen ME, Adekanmbi, Victor, Agrawal, Anurag, Ahmed, Muktar Beshir, Al-Aly, Ziyad, Alanezi, Fahad Mashhour, Alcalde-Rabanal, Jacqueline Elizabeth, Alipour, Vahid, Altirkawi, Khalid A, Alvis-Guzman, Nelson, Alvis-Zakzuk, Nelson J, Amegah, Adeladza Kofi, Amini, Saeed, Amiri, Fatemeh, Amugsi, Dickson A, Ancuceanu, Robert, Andrei, Catalina Liliana, Andrei, Tudorel, Antriyandarti, Ernoiz, Anvari, Davood, Arabloo, Jalal, Arab-Zozani, Morteza, Athari, Seyyed Shamsadin, Ausloos, Marcel, Ayano, Getinet, Aynalem, Yared Asmare, Azari, Samad, Badiye, Ashish D, Baig, Atif Amin, Balakrishnan, Kalpana, Banach, Maciej, Basu, Sanjay, Bedi, Neeraj, Bell, Michelle L, Bennett, Derrick A, Bhattacharyya, Krittika, Bhutta, Zulfiqar A, Bibi, Sadia, Bohlouli, Somayeh, Boufous, Soufiane, Bragazzi, Nicola Luigi, Braithwaite, Dejana, Burugina Nagaraja, Sharath, Butt, Zahid A, Caetano dos Santos, Florentino Luciano, Car, Josip, Cárdenas, Rosario, Carvalho, Felix, Castaldelli-Maia, Joao Mauricio, Castañeda-Orjuela, Carlos A, Cerin, Ester, Chattu, Soosanna Kumary, Chattu, Vijay Kumar, Chaturvedi, Pankaj, Chaturvedi, Sarika, Chen, Simiao, Chu, Dinh-Toi, Chung, Sheng-Chia, Dahlawi, Saad M A, Damiani, Giovanni, Dandona, Lalit, Dandona, Rakhi, Darwesh, Aso Mohammad, Das, Jai K, Dash, Aditya Prasad, Dávila-Cervantes, Claudio Alberto, De Leo, Diego, De Neve, Jan-Walter, Demissie, Getu Debalkie, Denova-Gutiérrez, Edgar, Dey, Sagnik, Dharmaratne, Samath Dhamminda, Dhimal, Meghnath, Dhungana, Govinda Prasad, Diaz, Daniel, Dipeolu, Isaac Oluwafemi, Dorostkar, Fariba, Doshmangir, Leila, Duraes, Andre Rodrigues, Edinur, Hisham Atan, Efendi, Ferry, El Tantawi, Maha, Eskandarieh, Sharareh, Fadhil, Ibtihal, Fattahi, Nazir, Fauk, Nelsensius Klau, Fereshtehnejad, Seyed-Mohammad, Folayan, Morenike Oluwatoyin, Foroutan, Masoud, Fukumoto, Takeshi, Gaidhane, Abhay Motiramji, Ghafourifard, Mansour, Ghashghaee, Ahmad, Gilani, Syed Amir, Gill, Tiffany K, Goulart, Alessandra C, Goulart, Bárbara Niegia Garcia, Grada, Ayman, Gubari, Mohammed Ibrahim Mohialdeen, Guido, Davide, Guo, Yuming, Gupta, Rajat Das, Gupta, Rajeev, Gutiérrez, Reyna Alma, Hafezi-Nejad, Nima, Hamadeh, Randah R, Hasaballah, Ahmed I, Hassanipour, Soheil, Hayat, Khezar, Heibati, Behzad, Heidari-Soureshjani, Reza, Henry, Nathaniel J, Herteliu, Claudiu, Hosseinzadeh, Mehdi, Hsairi, Mohamed, Hu, Guoqing, Ibitoye, Segun Emmanuel, Ilesanmi, Olayinka Stephen, Ilic, Irena M, Ilic, Milena D, Irvani, Seyed Sina Naghibi, Islam, Sheikh Mohammed Shariful, Iwu, Chidozie C D, Jaafari, Jalil, Jakovljevic, Mihajlo, Javaheri, Tahereh, Jha, Ravi Prakash, Ji, John S, Jonas, Jost B, Kabir, Ali, Kabir, Zubair, Kalhor, Rohollah, Kamyari, Naser, Kanchan, Tanuj, Kapil, Umesh, Kapoor, Neeti, Kayode, Gbenga A, Keiyoro, Peter Njenga, Khader, Yousef Saleh, Khalid, Nauman, Khan, Ejaz Ahmad, Khan, Maseer, Khan, Md Nuruzzaman, Khatab, Khaled, Khater, Mona M, Khatib, Mahalaqua Nazli, Khayamzadeh, Maryam, Khubchandani, Jagdish, Kim, Gyu Ri, Kim, Yun Jin, Kimokoti, Ruth W, Kisa, Adnan, Kisa, Sezer, Knibbs, Luke D, Koul, Parvaiz A, Koyanagi, Ai, Krishan, Kewal, Kumar, G Anil, Kumar, Manasi, Kusuma, Dian, La Vecchia, Carlo, Lacey, Ben, Lami, Faris Hasan, Lan, Qing, Lasrado, Savita, Lauriola, Paolo, Lee, Paul H, Lewycka, Sonia, Li, Shanshan, Machado, Daiane Borges, Mahasha, Phetole Walter, Maheri, Mina, Majeed, Azeem, Maleki, Afshin, Malekzadeh, Reza, Malta, Deborah Carvalho, Mansouri, Borhan, Mansournia, Mohammad Ali, Martinez, Natalie Maria, Martini, Santi, Martins-Melo, Francisco Rogerlândio, Mayala, Benjamin K, Mehndiratta, Man Mohan, Mendoza, Walter, Menezes, Ritesh G, Mengesha, Endalkachew Worku, Meretoja, Tuomo J, Mestrovic, Tomislav, Michalek, Irmina Maria, Mirrakhimov, Erkin M, Mirzaei, Maryam, Mirzaei, Roya, Moazen, Babak, Mohammad, Yousef, Mohammadian-Hafshejani, Abdollah, Mohammed, Shafiu, Mokdad, Ali H, Monasta, Lorenzo, Moradi-Lakeh, Maziar, Moraga, Paula, Morawska, Lidia, Mosapour, Abbas, Mouodi, Simin, Mousavi Khaneghah, Amin, Mukhopadhyay, Satinath, Munro, Sandra B, Murray, Christopher J L, Nagarajan, Ahamarshan Jayaraman, Naghavi, Mohsen, Nair, Sanjeev, Nangia, Vinay, Nascimento, Bruno Ramos, Nazari, Javad, Negoi, Ionut, Netsere, Henok Biresaw, Ngunjiri, Josephine W, Nguyen, Huong Lan Thi, Noubiap, Jean Jacques, Oancea, Bogdan, Ogbo, Felix Akpojene, Oh, In-Hwan, Olagunju, Andrew T, Olusanya, Bolajoko Olubukunola, Olusanya, Jacob Olusegun, Omar Bali, Ahmed, Onwujekwe, Obinna E, Otstavnov, Nikita, Otstavnov, Stanislav S, Owolabi, Mayowa O, P A, Mahesh, Pandey, Anamika, Park, Eun-Cheol, Park, Eun-Kee, Patel, Sangram Kishor, Pham, Hai Quang, Pilgrim, Thomas, Pirsaheb, Meghdad, Pokhrel, Khem Narayan, Postma, Maarten J, Quazi Syed, Zahiruddin, Rabiee, Navid, Radfar, Amir, Rahim, Fakher, Rahman, Mohammad Hifz Ur, Rahman, Muhammad Aziz, Rahmani, Amir Masoud, Ranabhat, Chhabi Lal, Rao, Sowmya J, Rasella, Davide, Rastogi, Prateek, Rath, Goura Kishor, Rawaf, David Laith, Rawaf, Salman, Rawal, Lal, Rawassizadeh, Reza, Renzaho, Andre M N, Reshmi, Bhageerathy, Rezaei, Negar, Rezaei, Nima, Rezapour, Aziz, Rickard, Jennifer, Roever, Leonardo, Ronfani, Luca, Rostamian, Morteza, Rubagotti, Enrico, Rwegerera, Godfrey M, Saddik, Basema, Sadeghi, Ehsan, Saeedi Moghaddam, Sahar, Sagar, Rajesh, Sahebkar, Amirhossein, Sahiledengle, Biniyam, Salem, Marwa Rashad, Samy, Abdallah M, Santric-Milicevic, Milena M, Saraswathy, Sivan Yegnanarayana Iyer, Sathian, Brijesh, Sathish, Thirunavukkarasu, Schwebel, David C, Sepanlou, Sadaf G, Shahabi, Saeed, Shaheen, Amira A, Shahid, Izza, Shaikh, Masood Ali, Shalash, Ali S, Shams-Beyranvand, Mehran, Shannawaz, Mohammed, Sharafi, Kiomars, Sheikh, Aziz, Sheikhbahaei, Sara, Shetty, Ranjitha S, Shiferaw, Wondimeneh Shibabaw, Shigematsu, Mika, Shin, Jae Il, Shivakumar, K M, Siabani, Soraya, Siddiqi, Tariq Jamal, Singh, Balbir Bagicha, Singh, Jasvinder A, Sintayehu, Yitagesu, Sorrie, Muluken Bekele, Soyiri, Ireneous N, Spurlock, Emma Elizabeth, Sreeramareddy, Chandrashekhar T, Stockfelt, Leo, Sufiyan, Mu'awiyyah Babale, Suliankatchi Abdulkader, Rizwan, Tabarés-Seisdedos, Rafael, Tabuchi, Takahiro, Taherkhani, Amir, Temsah, Mohamad-Hani, Thankappan, Kavumpurathu Raman, Tovani-Palone, Marcos Roberto, Traini, Eugenio, Ullah, Saif, Unnikrishnan, Bhaskaran, Upadhyay, Era, Valadan Tahbaz, Sahel, Varughese, Santosh, Violante, Francesco S, Vo, Bay, Vu, Giang Thu, Waheed, Yasir, Wang, Yuan-Pang, Welgan, Catherine A, Werdecker, Andrea, Yahyazadeh Jabbari, Seyed Hossein, Yaya, Sanni, Yazdi-Feyzabadi, Vahid, Yilma, Mekdes Tigistu, Yonemoto, Naohiro, Younis, Mustafa Z, Yousefinezhadi, Taraneh, Yu, Chuanhua, Yu, Yong, Zaman, Sojib Bin, Zhang, Yunquan, Zhang, Zhi-Jiang, Brauer, Michael, Hay, Simon I, and Reiner, Robert C, Jr

Published
2022
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56. Performance improvement of vapour compression refrigeration system using phase change material and thermoelectric generator

Author

Yogesh N. Nandanwar, Pramod V. Walke, Vednath P. Kalbande, and Man Mohan

Subjects
Phase change materials, Vapour compression refrigeration, Condenser, TEG, Heat, QC251-338.5
Abstract

The current study analyses how to boost the coefficient of performance (COP) of a vapour compression refrigeration system by introducing phase change material (PCM) and thermoelectric generator (TEG) into the system. The subcooled refrigerant was achieved by extracting heat through PCM in a separate PCM chamber positioned between the condenser and expansion valve. The heat stored in the PCM was provided to the TEG's hot side, while the cold side was served by an aluminium vessel carrying the condensed water yield accumulated from the evaporator coils. Electric power was generated due to the temperature difference on both sides of the TEG. Overall, the employment of PCM and TEG in a vapour compression refrigeration system boosted the cooling effect and COP while reduced the net amount of work required. The percent reduction in net-work required and the percent improvement in refrigeration system COP were 4% and 7%, respectively.

Published
2023
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59. Insights into the Design Principle of Heterojunction Ferro Dioxide Charge Plasma Vertical TFET for Biosensing Application.

Author

Singh, Shailendra, Shukla, Man Mohan, Chauhan, Puspraj Singh, and Jain, Ankit

Subjects
*FIELD-effect transistors, *MANUFACTURING processes, *NANOELECTROMECHANICAL systems, *DIELECTRIC function, *BIOSENSORS
Abstract

This study aims to reduce the fabrication complexity and cost of nanoscale devices by utilizing a Junction-less Vertical TFET based on charge plasma for unmarked detection in biological sensors. The Heterojunction Ferro dioxide charge plasma Vertical Tunnel Field Effect Transistor (HJ-F-CP-VTFET) architecture offers the potential to streamline manufacturing processes and lower production costs. A small gap in the gate dielectric is created by selectively etching away the gate oxide layer near the source end. Initially, the drain current characteristics of two devices, HJ-Si-CP-VTFET and HJ-F-CP-VTFET, are compared. Following this, the impact of varying the length, thickness, work function and dielectric constant of the gap under different bias settings is investigated to understand the sensing characteristics of the HJ-F-CP-VTFET. The biosensor is evaluated and compared with the HJ-F-CP-VTFET, focusing on parameters such as total current density, electron concentration, BTBT e-Tunneling rate, electric field, energy band diagram, electron and hole concentration and SRH recombination rate across a range of kvalues from 1 to 12. The ATLAS device simulator is used for all simulations and designs. For the value k = 12, the device HJ-F-CP-VTFET Ion/Ioff current ratio outcome is 1.116 × 1011. [ABSTRACT FROM AUTHOR]

Published
2024
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62. H-infinity Robust Control of DC-DC Converter

Author

Patra, Nabin Kumar, Garg, Man Mohan, Panda, Anup Kumar, Shukla, Rakesh Rajan, Kacprzyk, Janusz, Series Editor, Pal, Nikhil R., Advisory Editor, Bello Perez, Rafael, Advisory Editor, Corchado, Emilio S., Advisory Editor, Hagras, Hani, Advisory Editor, Kóczy, László T., Advisory Editor, Kreinovich, Vladik, Advisory Editor, Lin, Chin-Teng, Advisory Editor, Lu, Jie, Advisory Editor, Melin, Patricia, Advisory Editor, Nedjah, Nadia, Advisory Editor, Nguyen, Ngoc Thanh, Advisory Editor, Wang, Jun, Advisory Editor, Dash, Subhransu Sekhar, editor, Panigrahi, Bijaya Ketan, editor, and Das, Swagatam, editor

Published
2021
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64. Estimation of the global prevalence of dementia in 2019 and forecasted prevalence in 2050: an analysis for the Global Burden of Disease Study 2019

Author

Nichols, Emma, Steinmetz, Jaimie D, Vollset, Stein Emil, Fukutaki, Kai, Chalek, Julian, Abd-Allah, Foad, Abdoli, Amir, Abualhasan, Ahmed, Abu-Gharbieh, Eman, Akram, Tayyaba Tayyaba, Al Hamad, Hanadi, Alahdab, Fares, Alanezi, Fahad Mashhour, Alipour, Vahid, Almustanyir, Sami, Amu, Hubert, Ansari, Iman, Arabloo, Jalal, Ashraf, Tahira, Astell-Burt, Thomas, Ayano, Getinet, Ayuso-Mateos, Jose L, Baig, Atif Amin, Barnett, Anthony, Barrow, Amadou, Baune, Bernhard T, Béjot, Yannick, Bezabhe, Woldesellassie M Mequanint, Bezabih, Yihienew Mequanint, Bhagavathula, Akshaya Srikanth, Bhaskar, Sonu, Bhattacharyya, Krittika, Bijani, Ali, Biswas, Atanu, Bolla, Srinivasa Rao, Boloor, Archith, Brayne, Carol, Brenner, Hermann, Burkart, Katrin, Burns, Richard A, Cámera, Luis Alberto, Cao, Chao, Carvalho, Felix, Castro-de-Araujo, Luis F S, Catalá-López, Ferrán, Cerin, Ester, Chavan, Prachi P, Cherbuin, Nicolas, Chu, Dinh-Toi, Costa, Vera Marisa, Couto, Rosa A S, Dadras, Omid, Dai, Xiaochen, Dandona, Lalit, Dandona, Rakhi, De la Cruz-Góngora, Vanessa, Dhamnetiya, Deepak, Dias da Silva, Diana, Diaz, Daniel, Douiri, Abdel, Edvardsson, David, Ekholuenetale, Michael, El Sayed, Iman, El-Jaafary, Shaimaa I, Eskandari, Khalil, Eskandarieh, Sharareh, Esmaeilnejad, Saman, Fares, Jawad, Faro, Andre, Farooque, Umar, Feigin, Valery L, Feng, Xiaoqi, Fereshtehnejad, Seyed-Mohammad, Fernandes, Eduarda, Ferrara, Pietro, Filip, Irina, Fillit, Howard, Fischer, Florian, Gaidhane, Shilpa, Galluzzo, Lucia, Ghashghaee, Ahmad, Ghith, Nermin, Gialluisi, Alessandro, Gilani, Syed Amir, Glavan, Ionela-Roxana, Gnedovskaya, Elena V, Golechha, Mahaveer, Gupta, Rajeev, Gupta, Veer Bala, Gupta, Vivek Kumar, Haider, Mohammad Rifat, Hall, Brian J, Hamidi, Samer, Hanif, Asif, Hankey, Graeme J, Haque, Shafiul, Hartono, Risky Kusuma, Hasaballah, Ahmed I, Hasan, M Tasdik, Hassan, Amr, Hay, Simon I, Hayat, Khezar, Hegazy, Mohamed I, Heidari, Golnaz, Heidari-Soureshjani, Reza, Herteliu, Claudiu, Househ, Mowafa, Hussain, Rabia, Hwang, Bing-Fang, Iacoviello, Licia, Iavicoli, Ivo, Ilesanmi, Olayinka Stephen, Ilic, Irena M, Ilic, Milena D, Irvani, Seyed Sina Naghibi, Iso, Hiroyasu, Iwagami, Masao, Jabbarinejad, Roxana, Jacob, Louis, Jain, Vardhmaan, Jayapal, Sathish Kumar, Jayawardena, Ranil, Jha, Ravi Prakash, Jonas, Jost B, Joseph, Nitin, Kalani, Rizwan, Kandel, Amit, Kandel, Himal, Karch, André, Kasa, Ayele Semachew, Kassie, Gizat M, Keshavarz, Pedram, Khan, Moien AB, Khatib, Mahalaqua Nazli, Khoja, Tawfik Ahmed Muthafer, Khubchandani, Jagdish, Kim, Min Seo, Kim, Yun Jin, Kisa, Adnan, Kisa, Sezer, Kivimäki, Mika, Koroshetz, Walter J, Koyanagi, Ai, Kumar, G Anil, Kumar, Manasi, Lak, Hassan Mehmood, Leonardi, Matilde, Li, Bingyu, Lim, Stephen S, Liu, Xuefeng, Liu, Yuewei, Logroscino, Giancarlo, Lorkowski, Stefan, Lucchetti, Giancarlo, Lutzky Saute, Ricardo, Magnani, Francesca Giulia, Malik, Ahmad Azam, Massano, João, Mehndiratta, Man Mohan, Menezes, Ritesh G, Meretoja, Atte, Mohajer, Bahram, Mohamed Ibrahim, Norlinah, Mohammad, Yousef, Mohammed, Arif, Mokdad, Ali H, Mondello, Stefania, Moni, Mohammad Ali Ali, Moniruzzaman, Md, Mossie, Tilahun Belete, Nagel, Gabriele, Naveed, Muhammad, Nayak, Vinod C, Neupane Kandel, Sandhya, Nguyen, Trang Huyen, Oancea, Bogdan, Otstavnov, Nikita, Otstavnov, Stanislav S, Owolabi, Mayowa O, Panda-Jonas, Songhomitra, Pashazadeh Kan, Fatemeh, Pasovic, Maja, Patel, Urvish K, Pathak, Mona, Peres, Mario F P, Perianayagam, Arokiasamy, Peterson, Carrie B, Phillips, Michael R, Pinheiro, Marina, Piradov, Michael A, Pond, Constance Dimity, Potashman, Michele H, Pottoo, Faheem Hyder, Prada, Sergio I, Radfar, Amir, Raggi, Alberto, Rahim, Fakher, Rahman, Mosiur, Ram, Pradhum, Ranasinghe, Priyanga, Rawaf, David Laith, Rawaf, Salman, Rezaei, Nima, Rezapour, Aziz, Robinson, Stephen R, Romoli, Michele, Roshandel, Gholamreza, Sahathevan, Ramesh, Sahebkar, Amirhossein, Sahraian, Mohammad Ali, Sathian, Brijesh, Sattin, Davide, Sawhney, Monika, Saylan, Mete, Schiavolin, Silvia, Seylani, Allen, Sha, Feng, Shaikh, Masood Ali, Shaji, KS, Shannawaz, Mohammed, Shetty, Jeevan K, Shigematsu, Mika, Shin, Jae Il, Shiri, Rahman, Silva, Diego Augusto Santos, Silva, João Pedro, Silva, Renata, Singh, Jasvinder A, Skryabin, Valentin Yurievich, Skryabina, Anna Aleksandrovna, Smith, Amanda E, Soshnikov, Sergey, Spurlock, Emma Elizabeth, Stein, Dan J, Sun, Jing, Tabarés-Seisdedos, Rafael, Thakur, Bhaskar, Timalsina, Binod, Tovani-Palone, Marcos Roberto, Tran, Bach Xuan, Tsegaye, Gebiyaw Wudie, Valadan Tahbaz, Sahel, Valdez, Pascual R, Venketasubramanian, Narayanaswamy, Vlassov, Vasily, Vu, Giang Thu, Vu, Linh Gia, Wang, Yuan-Pang, Wimo, Anders, Winkler, Andrea Sylvia, Yadav, Lalit, Yahyazadeh Jabbari, Seyed Hossein, Yamagishi, Kazumasa, Yang, Lin, Yano, Yuichiro, Yonemoto, Naohiro, Yu, Chuanhua, Yunusa, Ismaeel, Zadey, Siddhesh, Zastrozhin, Mikhail Sergeevich, Zastrozhina, Anasthasia, Zhang, Zhi-Jiang, Murray, Christopher J L, and Vos, Theo

Published
2022
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66. Primary stroke prevention worldwide: translating evidence into action

Author

Abanto, Carlos, Abera, Semaw Ferede, Addissie, Adamu, Adebayo, Oluwadamilola, Adeleye, Amos Olufemi, Adilbekov, Yerzhan, Adilbekova, Bibigul, Adoukonou, Thierry Armel, Aguiar de Sousa, Diana, Ajagbe, Temitope, Akhmetzhanova, Zauresh, Akpalu, Albert, Álvarez Ahlgren, Jhon, Ameriso, Sebastián, Andonova, Silva, Awoniyi, Foloruso Emmanuel, Bakhiet, Moiz, Barboza, Miguel, Basri, Hamidon, Bath, Philip, Bello, Olamide, Bereczki, Dániel, Beretta, Simone, Berkowitz, Aaron, Bernabé-Ortiz, Antonio, Bernhardt, Julie, Berzina, Guna, Bisharyan, Mher, Bovet, Pascal, Budincevic, Hrvoje, Cadilhac, Dominique, Caso, Valeria, Chen, Christopher, Chin, Jerome, Chwojnicki, Kamil, Conforto, Adriana, Cruz, Vitor Tedim, D'Amelio, Marco, Danielyan, Kristine, Davis, Stephen, Demarin, Vida, Dempsey, Robert, Dichgans, Martin, Dokova, Klara, Donnan, Geoffrey, Elkind, Mitchell S., Endres, Matthias, Fischer, Urs, Gankpé, Fortuné, Gaye Saavedra, Andrés, Gil, Artyom, Giroud, Maurice, Gnedovskaya, Elena, Hachinski, Vladimir, Hafdi, Melanie, Hamadeh, Randah, Hamzat, T. Kolapo, Hankey, Graeme, Heldner, Mirjam, Ibrahim, Etedal Ahmed, Ibrahim, Norlinah Mohamed, Inoue, Manabu, Jee, Sungju, Jeng, Jiann-Shing, Kalkonde, Yogesh, Kamenova, Saltanat, Karaszewski, Bartosz, Kelly, Peter, Khan, Taskeen, Kiechl, Stefan, Kondybayeva, Aida, Kõrv, Janika, Kravchenko, Michael, Krishnamurthi, Rita V., Kruja, Jera, Lakkhanaloet, Mongkol, Langhorne, Peter, Lavados, Pablo M., Law, Zhe Kang, Lawal, Abisola, Lazo-Porras, Maria, Lebedynets, Dmytro, Lee, Tsong-Hai, Leung, Thomas, Liebeskind, David S., Lindsay, Patrice, López-Jaramillo, Patricio, Lotufo, Paulo Andrade, Machline-Carrion, Julia, Makanjuola, Akintomiwa, Markus, Hugh Stephen, Marquez-Romero, Juan Manuel, Medina, Marco, Medukhanova, Sabina, Mehndiratta, Man Mohan, Merkin, Alexandr, Mirrakhimov, Erkin, Mohl, Stephanie, Moscoso-Porras, Miguel, Müller-Stierlin, Annabel, Murphy, Sean, Musa, Kamarul Imran, Nasreldein, Ahmed, Nogueira, Raul Gomes, Nolte, Christian, Noubiap, Jean Jacques, Novarro-Escudero, Nelson, Ogun, Yomi, Oguntoye, Richard Ayobami, Oraby, Mohammed Ibrahim, Osundina, Morenike, Ovbiagele, Bruce, Orken, Dilek Necioglu, Ozdemir, Atilla Özcan, Ozturk, Serefnur, Paccot, Melanie, Phromjai, Jurairat, Piradov, Piradov, Platz, Thomas, Potpara, Tatjana, Ranta, Annemarei, Rathore, Farooq, Richard, Edo, Sacco, Ralph L., Sahathevan, Ramesh, Santos Carquín, Irving, Saposnik, Gustavo, Sarfo, Fred Stephen, Sharma, Mike, Sheth, Kevin, Shobhana, A., Suwanwela, Nijasri, Svyato, Irina, Sylaja, P.N., Tao, Xuanchen, Thakur, Kiran T., Toni, Danilo, Topcuoglu, Mehmet Akif, Torales, Julio, Towfighi, Amytis, Truelsen, Thomas Clement, Tsiskaridze, Alexander, Tulloch-Reid, Marshall, Useche, Nicolás, Vanacker, Peter, Vassilopoulou, Sophia, Vukorepa, Gorana, Vuletic, Vladimira, Wahab, Kolawole W., Wang, Wenzhi, Wijeratne, Tissa, Wolfe, Charles, Yifru, Yared Mamushet, Yock-Corrales, Adriana, Yonemoto, Naohiro, Yperzeele, Laetitia, Zhang, Puhong, Owolabi, Mayowa O, Thrift, Amanda G, Mahal, Ajay, Ishida, Marie, Martins, Sheila, Johnson, Walter D, Pandian, Jeyaraj, Abd-Allah, Foad, Yaria, Joseph, Phan, Hoang T, Roth, Greg, Gall, Seana L, Beare, Richard, Phan, Thanh G, Mikulik, Robert, Akinyemi, Rufus O, Norrving, Bo, Brainin, Michael, and Feigin, Valery L

Published
2022
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68. Air pollution and cerebrovascular disorders with special reference to Asia: An overview

Author

Bushra Taimuri, Sohail Lakhani, Maryam Javed, Divyani Garg, Vasundhara Aggarwal, Man Mohan Mehndiratta, and Mohammad Wasay

Subjects
air pollution, burden, covid-19, particulate matter, south asia, stroke, Neurology. Diseases of the nervous system, RC346-429
Abstract

Background: Among the primary environmental issues affecting global health, air pollution is considered the leading cause of concern. Globally, around 800,000 deaths were attributed to air pollution according to WHO. Evidence suggests that there has been a strong association of air pollution with stroke. Approximately, 25% of stroke mortality was due to air pollution according to a study in 2013. Objective: The aim of this review was to analyze the association between stroke, intracerebral hemorrhage, and subarachnoid hemorrhage and air pollution and its burden globally with a special focus on South Asia along with its association with the COVID-19 pandemic. Results: There is growing research data linking air pollution to cardiovascular disorders including stroke. Short-term and long-term air pollution exposures have been shown to increase stroke incidence in epidemiological data. Air pollution, both gaseous and particle, show a strong and tight temporal relationship with stroke hospitalizations and death. The link between ICH and SAH to air pollution is less strong and less well studied as compared to ischemic stroke. Stroke and air pollution both are highly prevalent in South Asia. It is possible that the high prevalence of stroke in south Asia may be linked to the high frequency of air pollution in addition to other conventional risk factors. Decreased stroke admissions and mortality and reduced cardiovascular mortality reported during coronavirus disease 2019 (COVID) lockdown may be attributable to decreased levels of air pollution. Conclusion: Even though air pollution poses a significant threat to human health, a great number of countries still fail to achieve internationally agreed air quality standards. Air pollution should be recognized among the most significant controllable risk factors for cardiovascular and cerebrovascular disease prevention and treatment.

Published
2022
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69. Air pollution and headache disorders

Author

Divyani Garg, Man Mohan Mehndiratta, Mohammad Wasay, and Vasundhara Aggarwal

Subjects
migraine, nitrogen dioxide, particulate matter, pollution, sulfur dioxide, Neurology. Diseases of the nervous system, RC346-429
Abstract

Air pollution, the most prevalent form of pollution worldwide, is associated with a wide range of neurological disorders, including neurodegenerative conditions, stroke, autism, depression, and developmental delay. There is accumulating evidence on the association between air pollution and headache disorders, especially migraine. Many classical and non-classical air pollutants have been associated with headache, including particulate matter, nitrogen dioxide, sulfur dioxide, ozone, carbon monoxide, as well as polycyclic aromatic hydrocarbons and volatile organic compounds. There has also been research on the impact of biomass fuels on health-related symptoms, including headache, which form an important source of air pollution in our country. The exact mechanisms underlying headache pathophysiology vis-à-vis air pollution are not precisely defined but include triggering of neuroinflammation and activation of the transient receptor potential ankyrin 1 (TRPA1)-associated pathways. Evidence from different regions of the world indicates a significant association between headache incidence and prevalence, and occurrence of air pollution. Despite growing data, research on adverse effects of air pollution on headache disorders remains limited, and appropriate outcome measures are not holistically defined in these studies. Due to the rapid advancement of the scourge of air pollution, there is a pressing need to expand the arena of research, specifically focused on pathological mechanisms, impact on health and quality-of-life parameters, as well as broader global ramifications.

Published
2022
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70. Synthesis of hydrocortisone containing dietary fiber almond gum-based hydrogels as sustained drug delivery carriers for use in colon inflammation

Author

Baljit Singh, Man Mohan, and Rajender Kumar

Subjects
Dietary fiber, Almond gum, Drug delivery, Nutrition. Foods and food supply, TX341-641, Nutritional diseases. Deficiency diseases, RC620-627
Abstract

Keeping in view the advantages of the dietary fiber almond gum in food and health care, herein this work, modification of the gum has been carried out to prepare the hydrogels for use as drug delivery systems (DDS). The almond gum-polyacrylic acid hydrogels containing hydrocortisone drug were synthesized to improve the therapeutic potential of the drug to treat colon inflammation. The polyacrylic acid was grafted onto almond gum in the presence of a crosslinker to form the hydrogels. These co-polymers were characterized by FTIR, XRD, 13C NMR, and microscopic analysis. The in vitro drug release and various properties such as thrombogenecity, haemolytic potential, mucoadhesion test, antioxidant activity, and gel strength of hydrogels and bigels were measured. The incorporation of the polyacrylic acid into the hydrogel network was observed due to the presence of an intense peak at 1705.00 cm−1 in FTIR spectra and a peak at 178.44 (C=O) of poly(AAc) in 13C NMR along with the broad XRD due to amorphous nature of hydrogels. Further, during microscopic analysis, it has been found that as the content of the organogel was increased in the biphasic bigel matrix, the dimensions of the droplets (number and size) were enlarged. The results of properties indicated that bigel formation has enhanced the thrombogenecity, mucoadhesion and antioxidant activity of the hydrogel formulations. However, the addition of organogel in the hydrogels has reduced the gel strength. The gel strength of hydrogel was found higher (5.46 ± 0.09N) than bigel (2.32 ± 0.28 N). The values of haemolytic index of the hydrogel and bigel matrix were less than 2% indicating the biocompatible nature of the material. The release of hydrocortisone from DDS occurred in a slow and sustained manner with non-Fickian diffusion in colonic pH 7.4.

Published
2022
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71. Development of dietary fiber psyllium based hydrogel for use in drug delivery applications

Author

Baljit Singh, Vikrant Sharma, Rajender Kumar, and Man Mohan

Subjects
Psyllium mucilage, Hydrogels, Crosslinking, Drug delivery, Nutrition. Foods and food supply, TX341-641, Nutritional diseases. Deficiency diseases, RC620-627
Abstract

Keeping in view the therapeutic and gel forming role of the psyllium seed mucilage in pharmaceutical industries, herein this article, its potential has been explored for developing the drug delivery (DD) carrier. The main aim of the study was to modify the psyllium polysaccharides through grafting and crosslinking of 2-methacryloyloxyethyl trimethylammonium chloride onto psyllium to develop the hydrogels for use in DD application. Various thermal, mechanical, physiochemical, biomedical properties of the hydrogel were determined along with characterization with 13C NMR, FTIR, XRD, TGA, DSC and AFM. The release of antibiotic drug cefuroxime occurred in sustained manner and followed Fickian diffusion mechanism and was best fitted in Higuchi kinetic model. The networks showed mesh size in the range between 25.14 to 38.92 nm during the change in crosslinker content in copolymerization reaction. It has been inferred from the results that these hydrogels could be used as a potential carrier for drug delivery.

Published
2022
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72. Development of dietary fibers moringa-sterculia gum hydrogel for drug delivery applications

Author

Baljit Singh, Vikrant Sharma, Rajneesh, Ajay Kumar, Rohit, Man Mohan, Rajender Kumar, Ankita Kumari, Prerna Sharma, and Kaka Ram

Subjects
Moringa gum, Sterculia gum, Co-polymeric hydrogels, Levofloxacin, Wound dressings, Nutrition. Foods and food supply, TX341-641, Nutritional diseases. Deficiency diseases, RC620-627
Abstract

Introduction: Keeping in view the role of polysaccharide gums in pharmaceutical applications. Herein this research, Moringa gum (MOG) and Sterculia gum (SG) polysaccharides have been explored to design the network structure in the form of hydrogels which can act as a wound dressing for better wound healing. Both gums are hydrophilic stem exudate and their anti-fungal and antioxidant activities have been reported for wound healing which can help the increase in wound healing potential of the antibiotic drug encapsulated hydrogel dressings. Objectives: To design the moringa gum, sterculia gum and polyacrylic acid based hydrogel wound dressings by graft copolymerization method impregnated with antibiotic drug levofloxacin for better wound care. Methodology: The co-polymers were prepared by grafting and crosslinking of the polyacrylic acid onto MOG and SG. The copolymers were characterized by cryo-SEM, AFM, FTIR, 13C NMR and swelling studies along with the evaluation of blood compatibility, wound fluid absorption, antioxidant activity, permeability (O2, H2O and, microbial), mucoadhesion, mechanical and in vitro release dynamics of antibiotic drug levofloxacin. Results and conclusion: The Cryo-SEM and AFM images of the hydrogels showed the porous nature and rough surface morphology of the hydrogels. The porosity in the hydrogel controlled the wound fluid absorption and drug diffusion from dressing. The release of the levofloxacin from MOG-cl-SG-co-poly(AAc) hydrogel occurred by the non-Fickian diffusion mechanism and release profile was best fitted in the Korsmeyer-Peppas kinetic model of drug release in the simulated wound fluid . The gum-based dressings were found permeable and antioxidant in nature. Overall, these hydrogels could be proposed as suitable materials for biomedical applications including drug delivery and wound dressing for better wound care.

Published
2022
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80. Artificial Neural Network Based Load Balancing in Cloud Environment

Author

Negi, Sarita, Panwar, Neelam, Vaisla, Kunwar Singh, Rauthan, Man Mohan Singh, Kacprzyk, Janusz, Series Editor, Gomide, Fernando, Advisory Editor, Kaynak, Okyay, Advisory Editor, Liu, Derong, Advisory Editor, Pedrycz, Witold, Advisory Editor, Polycarpou, Marios M., Advisory Editor, Rudas, Imre J., Advisory Editor, Wang, Jun, Advisory Editor, Kolhe, Mohan L., editor, Tiwari, Shailesh, editor, Trivedi, Munesh C., editor, and Mishra, Krishn K., editor

Published
2020
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81. Stroke in Patients with Diabetes: Is It Time to Expand Public Health Priority to Encompass High-Risk Patients with Increased Insulin Resistance?

Author

Sian Alexandra Bradley, Francis Muttamthottil Varghese, Bindu Menon, Man Mohan Mehndiratta, and Sonu Menachem Maimonides Bhaskar

Subjects
Diseases of the endocrine glands. Clinical endocrinology, RC648-665
Abstract

Diabetes and stroke, with an interlinking aetiology, contribute to a growing cardiovascular disease burden and mortality around the world. Given the disproportionate prevalence and the burden of these conditions in the developing world, as well as the high risk of both Type 2 diabetes and cardiovascular disease carried by patients with metabolic syndrome, public health strategies are vital to mitigate the impact. Systematic approaches towards identifying undiagnosed patients in the community and building health systems around those targeted interventions have been implemented. However, growing evidence indicates potential for approaches to capture high-risk patients, such as those who suffer from pre-diabetes or increased insulin resistance, to provide early and optimal treatments, which could translate to population-level benefits, including reduced prevalence, disability, and disease burden.

Published
2021
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82. Global, regional, and national mortality among young people aged 10–24 years, 1950–2019: a systematic analysis for the Global Burden of Disease Study 2019

Author

Ward, Joseph L, Azzopardi, Peter S, Francis, Kate Louise, Santelli, John S, Skirbekk, Vegard, Sawyer, Susan M, Kassebaum, Nicholas J, Mokdad, Ali H, Hay, Simon I, Abd-Allah, Foad, Abdoli, Amir, Abdollahi, Mohammad, Abedi, Aidin, Abolhassani, Hassan, Abreu, Lucas Guimarães, Abrigo, Michael R M, Abu-Gharbieh, Eman, Abushouk, Abdelrahman I, Adebayo, Oladimeji M, Adekanmbi, Victor, Adham, Davoud, Advani, Shailesh M, Afshari, Khashayar, Agrawal, Anurag, Ahmad, Tauseef, Ahmadi, Keivan, Ahmed, Anwar E, Aji, Budi, Akombi-Inyang, Blessing, Alahdab, Fares, Al-Aly, Ziyad, Alam, Khurshid, Alanezi, Fahad Mashhour, Alanzi, Turki M, Alcalde-Rabanal, Jacqueline Elizabeth, Alemu, Biresaw Wassihun, Al-Hajj, Samar, Alhassan, Robert Kaba, Ali, Saqib, Alicandro, Gianfranco, Alijanzadeh, Mehran, Aljunid, Syed Mohamed, Almasi-Hashiani, Amir, Almasri, Nihad A, Al-Mekhlafi, Hesham M, Alonso, Jordi, Al-Raddadi, Rajaa M, Altirkawi, Khalid A, Alvis-Guzman, Nelson, Amare, Azmeraw T, Amini, Saeed, Aminorroaya, Arya, Amit, Arianna Maever L, Amugsi, Dickson A, Ancuceanu, Robert, Anderlini, Deanna, Andrei, Catalina Liliana, Androudi, Sofia, Ansari, Fereshteh, Ansari, Iman, Antonio, Carl Abelardo T, Anvari, Davood, Anwer, Razique, Appiah, Seth Christopher Yaw, Arabloo, Jalal, Arab-Zozani, Morteza, Ärnlöv, Johan, Asaad, Malke, Asadi-Aliabadi, Mehran, Asadi-Pooya, Ali A, Atout, Maha Moh'd Wahbi, Ausloos, Marcel, Avenyo, Elvis Korku, Avila-Burgos, Leticia, Ayala Quintanilla, Beatriz Paulina, Ayano, Getinet, Aynalem, Yared Asmare, Azari, Samad, Azene, Zelalem Nigussie, Bakhshaei, Mohammad Hossein, Bakkannavar, Shankar M, Banach, Maciej, Banik, Palash Chandra, Barboza, Miguel A, Barker-Collo, Suzanne Lyn, Bärnighausen, Till Winfried, Basu, Sanjay, Baune, Bernhard T, Bayati, Mohsen, Bedi, Neeraj, Beghi, Ettore, Bekuma, Tariku Tesfaye, Bell, Arielle Wilder, Bell, Michelle L, Benjet, Corina, Bensenor, Isabela M, Berhe, Abadi Kidanemariam, Berhe, Kidanemaryam, Berman, Adam E, Bhagavathula, Akshaya Srikanth, Bhardwaj, Nikha, Bhardwaj, Pankaj, Bhattacharyya, Krittika, Bhattarai, Suraj, Bhutta, Zulfiqar A, Bijani, Ali, Bikbov, Boris, Biondi, Antonio, Birhanu, Tesega Tesega Mengistu, Biswas, Raaj Kishore, Bohlouli, Somayeh, Bolla, Srinivasa Rao, Boloor, Archith, Borschmann, Rohan, Boufous, Soufiane, Bragazzi, Nicola Luigi, Braithwaite, Dejana, Breitborde, Nicholas J K, Brenner, Hermann, Britton, Gabrielle B, Burns, Richard A, Burugina Nagaraja, Sharath, Butt, Zahid A, Caetano dos Santos, Florentino Luciano, Cámera, Luis Alberto, Campos-Nonato, Ismael R, Campuzano Rincon, Julio Cesar, Cárdenas, Rosario, Carreras, Giulia, Carrero, Juan J, Carvalho, Felix, Castaldelli-Maia, Joao Mauricio, Castañeda-Orjuela, Carlos A, Castelpietra, Giulio, Catalá-López, Ferrán, Cerin, Ester, Chandan, Joht Singh, Chang, Hsing-Yi, Chang, Jung-Chen, Charan, Jaykaran, Chattu, Vijay Kumar, Chaturvedi, Sarika, Choi, Jee-Young Jasmine, Chowdhury, Mohiuddin Ahsanul Kabir, Christopher, Devasahayam J, Chu, Dinh-Toi, Chung, Michael T, Chung, Sheng-Chia, Cicuttini, Flavia M, Constantin, Traian Vasile, Costa, Vera Marisa, Dahlawi, Saad M A, Dai, Haijiang, Dai, Xiaochen, Damiani, Giovanni, Dandona, Lalit, Dandona, Rakhi, Daneshpajouhnejad, Parnaz, Darwesh, Aso Mohammad, Dávila-Cervantes, Claudio Alberto, Davletov, Kairat, De la Hoz, Fernando Pio, De Leo, Diego, Dervenis, Nikolaos, Desai, Rupak, Desalew, Assefa, Deuba, Keshab, Dharmaratne, Samath Dhamminda, Dhungana, Govinda Prasad, Dianatinasab, Mostafa, Dias da Silva, Diana, Diaz, Daniel, Didarloo, Alireza, Djalalinia, Shirin, Dorostkar, Fariba, Doshi, Chirag P, Doshmangir, Leila, Doyle, Kerrie E, Duraes, Andre Rodrigues, Ebrahimi Kalan, Mohammad, Ebtehaj, Sanam, Edvardsson, David, El Tantawi, Maha, Elgendy, Islam Y, El-Jaafary, Shaimaa I, Elsharkawy, Aisha, Eshrati, Babak, Eskandarieh, Sharareh, Esmaeilnejad, Saman, Esmaeilzadeh, Firooz, Esteghamati, Sadaf, Faro, Andre, Farzadfar, Farshad, Fattahi, Nazir, Feigin, Valery L, Ferede, Tomas Y, Fereshtehnejad, Seyed-Mohammad, Fernandes, Eduarda, Ferrara, Pietro, Filip, Irina, Fischer, Florian, Fisher, James L, Foigt, Nataliya A, Folayan, Morenike Oluwatoyin, Fomenkov, Artem Alekseevich, Foroutan, Masoud, Fukumoto, Takeshi, Gad, Mohamed M, Gaidhane, Abhay Motiramji, Gallus, Silvano, Gebre, Teshome, Gebremedhin, Ketema Bizuwork, Gebremeskel, Gebreamlak Gebremedhn, Gebremeskel, Leake, Gebreslassie, Assefa Ayalew, Gesesew, Hailay Abrha, Ghadiri, Keyghobad, Ghafourifard, Mansour, Ghamari, Farhad, Ghashghaee, Ahmad, Gilani, Syed Amir, Gnedovskaya, Elena V, Godinho, Myron Anthony, Golechha, Mahaveer, Goli, Srinivas, Gona, Philimon N, Gopalani, Sameer Vali, Gorini, Giuseppe, Grivna, Michal, Gubari, Mohammed Ibrahim Mohialdeen, Gugnani, Harish Chander, Guimarães, Rafael Alves, Guo, Yuming, Gupta, Rajeev, Haagsma, Juanita A, Hafezi-Nejad, Nima, Haile, Teklehaimanot Gereziher, Haj-Mirzaian, Arvin, Haj-Mirzaian, Arya, Hall, Brian J, Hamadeh, Randah R, Hamagharib Abdullah, Kanaan, Hamidi, Samer, Handiso, Demelash Woldeyohannes, Hanif, Asif, Hankey, Graeme J, Haririan, Hamidreza, Haro, Josep Maria, Hasaballah, Ahmed I, Hashi, Abdiwahab, Hassan, Amr, Hassanipour, Soheil, Hassankhani, Hadi, Hayat, Khezar, Heidari-Soureshjani, Reza, Herteliu, Claudiu, Heydarpour, Fatemeh, Ho, Hung Chak, Hole, Michael K, Holla, Ramesh, Hoogar, Praveen, Hosseini, Mostafa, Hosseinzadeh, Mehdi, Hostiuc, Mihaela, Hostiuc, Sorin, Househ, Mowafa, Hsairi, Mohamed, Huda, Tanvir M, Humayun, Ayesha, Hussain, Rabia, Hwang, Bing-Fang, Iavicoli, Ivo, Ibitoye, Segun Emmanuel, Ilesanmi, Olayinka Stephen, Ilic, Irena M, Ilic, Milena D, Inbaraj, Leeberk Raja, Intarut, Nirun, Iqbal, Usman, Irvani, Seyed Sina Naghibi, Islam, M Mofizul, Islam, Sheikh Mohammed Shariful, Iso, Hiroyasu, Ivers, Rebecca Q, Jahani, Mohammad Ali, Jakovljevic, Mihajlo, Jalali, Amir, Janodia, Manthan Dilipkumar, Javaheri, Tahereh, Jeemon, Panniyammakal, Jenabi, Ensiyeh, Jha, Ravi Prakash, Jha, Vivekanand, Ji, John S, Jonas, Jost B, Jones, Kelly M, Joukar, Farahnaz, Jozwiak, Jacek Jerzy, Juliusson, Petur B, Jürisson, Mikk, Kabir, Ali, Kabir, Zubair, Kalankesh, Leila R, Kalhor, Rohollah, Kamyari, Naser, Kanchan, Tanuj, Karch, André, Karimi, Salah Eddin, Kaur, Supreet, Kayode, Gbenga A, Keiyoro, Peter Njenga, Khalid, Nauman, Khammarnia, Mohammad, Khan, Maseer, Khan, Md Nuruzzaman, Khatab, Khaled, Khater, Mona M, Khatib, Mahalaqua Nazli, Khayamzadeh, Maryam, Khazaie, Habibolah, Khoja, Abdullah T, Kieling, Christian, Kim, Young-Eun, Kim, Yun Jin, Kimokoti, Ruth W, Kisa, Adnan, Kisa, Sezer, Kivimäki, Mika, Koolivand, Ali, Kosen, Soewarta, Koyanagi, Ai, Krishan, Kewal, Kugbey, Nuworza, Kumar, G Anil, Kumar, Manasi, Kumar, Nithin, Kurmi, Om P, Kusuma, Dian, La Vecchia, Carlo, Lacey, Ben, Lal, Dharmesh Kumar, Lalloo, Ratilal, Lan, Qing, Landires, Iván, Lansingh, Van Charles, Larsson, Anders O, Lasrado, Savita, Lassi, Zohra S, Lauriola, Paolo, Lee, Paul H, Lee, Shaun Wen Huey, Leigh, James, Leonardi, Matilde, Leung, Janni, Levi, Miriam, Lewycka, Sonia, Li, Bingyu, Li, Ming-Chieh, Li, Shanshan, Lim, Lee-Ling, Lim, Stephen S, Liu, Xuefeng, Lorkowski, Stefan, Lotufo, Paulo A, Lunevicius, Raimundas, Maddison, Ralph, Mahasha, Phetole Walter, Mahdavi, Mokhtar Mahdavi, Mahmoudi, Morteza, Majeed, Azeem, Maleki, Afshin, Malekzadeh, Reza, Malta, Deborah Carvalho, Mamun, Abdullah A, Mansouri, Borhan, Mansournia, Mohammad Ali, Martinez, Gabriel, Martinez-Raga, Jose, Martins-Melo, Francisco Rogerlândio, Mason-Jones, Amanda J, Masoumi, Seyedeh Zahra, Mathur, Manu Raj, Maulik, Pallab K, McGrath, John J, Mehndiratta, Man Mohan, Mehri, Fereshteh, Memiah, Peter T N, Mendoza, Walter, Menezes, Ritesh G, Mengesha, Endalkachew Worku, Meretoja, Atte, Meretoja, Tuomo J, Mestrovic, Tomislav, Miazgowski, Bartosz, Miazgowski, Tomasz, Michalek, Irmina Maria, Miller, Ted R, Mini, GK, Mirica, Andreea, Mirrakhimov, Erkin M, Mirzaei, Hamed, Mirzaei, Maryam, Moazen, Babak, Mohammad, Dara K, Mohammadi, Shadieh, Mohammadian-Hafshejani, Abdollah, Mohammadifard, Noushin, Mohammadpourhodki, Reza, Mohammed, Shafiu, Monasta, Lorenzo, Moradi, Ghobad, Moradi-Lakeh, Maziar, Moradzadeh, Rahmatollah, Moraga, Paula, Morrison, Shane Douglas, Mosapour, Abbas, Mousavi Khaneghah, Amin, Mueller, Ulrich Otto, Muriithi, Moses K, Murray, Christopher J L, Muthupandian, Saravanan, Naderi, Mehdi, Nagarajan, Ahamarshan Jayaraman, Naghavi, Mohsen, Naimzada, Mukhammad David, Nangia, Vinay, Nayak, Vinod C, Nazari, Javad, Ndejjo, Rawlance, Negoi, Ionut, Negoi, Ruxandra Irina, Netsere, Henok Biresaw, Nguefack-Tsague, Georges, Nguyen, Diep Ngoc, Nguyen, Huong Lan Thi, Nie, Jing, Ningrum, Dina Nur Anggraini, Nnaji, Chukwudi A, Nomura, Shuhei, Noubiap, Jean Jacques, Nowak, Christoph, Nuñez-Samudio, Virginia, Ogbo, Felix Akpojene, Oghenetega, Onome Bright, Oh, In-Hwan, Oladnabi, Morteza, Olagunju, Andrew T, Olusanya, Bolajoko Olubukunola, Olusanya, Jacob Olusegun, Omar Bali, Ahmed, Omer, Muktar Omer, Onwujekwe, Obinna E, Ortiz, Alberto, Otoiu, Adrian, Otstavnov, Nikita, Otstavnov, Stanislav S, Øverland, Simon, Owolabi, Mayowa O, P A, Mahesh, Padubidri, Jagadish Rao, Pakshir, Keyvan, Palladino, Raffaele, Pana, Adrian, Panda-Jonas, Songhomitra, Pandey, Anamika, Panelo, Carlo Irwin Able, Park, Eun-Kee, Patten, Scott B, Peden, Amy E, Pepito, Veincent Christian Filipino, Peprah, Emmanuel K, Pereira, Jeevan, Pesudovs, Konrad, Pham, Hai Quang, Phillips, Michael R, Piradov, Michael A, Pirsaheb, Meghdad, Postma, Maarten J, Pottoo, Faheem Hyder, Pourjafar, Hadi, Pourshams, Akram, Prada, Sergio I, Pupillo, Elisabetta, Quazi Syed, Zahiruddin, Rabiee, Mohammad Hasan, Rabiee, Navid, Radfar, Amir, Rafiee, Ata, Raggi, Alberto, Rahim, Fakher, Rahimi-Movaghar, Vafa, Rahman, Mohammad Hifz Ur, Rahman, Muhammad Aziz, Ramezanzadeh, Kiana, Ranabhat, Chhabi Lal, Rao, Sowmya J, Rashedi, Vahid, Rastogi, Prateek, Rathi, Priya, Rawaf, David Laith, Rawaf, Salman, Rawal, Lal, Rawassizadeh, Reza, Renzaho, Andre M N, Rezaei, Negar, Rezaei, Nima, Rezai, Mohammad sadegh, Riahi, Seyed Mohammad, Rickard, Jennifer, Roever, Leonardo, Ronfani, Luca, Roth, Gregory A, Rubagotti, Enrico, Rumisha, Susan Fred, Rwegerera, Godfrey M, Sabour, Siamak, Sachdev, Perminder S, Saddik, Basema, Sadeghi, Ehsan, Saeedi Moghaddam, Sahar, Sagar, Rajesh, Sahebkar, Amirhossein, Sahraian, Mohammad Ali, Sajadi, S Mohammad, Salem, Marwa Rashad, Salimzadeh, Hamideh, Samy, Abdallah M, Sanabria, Juan, Santric-Milicevic, Milena M, Saraswathy, Sivan Yegnanarayana Iyer, Sarrafzadegan, Nizal, Sarveazad, Arash, Sathish, Thirunavukkarasu, Sattin, Davide, Saxena, Deepak, Saxena, Sonia, Schiavolin, Silvia, Schwebel, David C, Schwendicke, Falk, Senthilkumaran, Subramanian, Sepanlou, Sadaf G, Sha, Feng, Shafaat, Omid, Shahabi, Saeed, Shaheen, Amira A, Shaikh, Masood Ali, Shakiba, Saeed, Shamsi, MohammadBagher, Shannawaz, Mohammed, Sharafi, Kiomars, Sheikh, Aziz, Sheikhbahaei, Sara, Shetty, B Suresh Kumar, Shi, Peilin, Shigematsu, Mika, Shin, Jae Il, Shiri, Rahman, Shuval, Kerem, Siabani, Soraya, Sigfusdottir, Inga Dora, Sigurvinsdottir, Rannveig, Silva, Diego Augusto Santos, Silva, João Pedro, Simonetti, Biagio, Singh, Jasvinder A, Singh, Virendra, Sinke, Abiy H, Skryabin, Valentin Yurievich, Slater, Helen, Smith, Emma U R, Sobhiyeh, Mohammad Reza, Sobngwi, Eugene, Soheili, Amin, Somefun, Oluwaseyi Dolapo, Sorrie, Muluken Bekele, Soyiri, Ireneous N, Sreeramareddy, Chandrashekhar T, Stein, Dan J, Stokes, Mark A, Sudaryanto, Agus, Sultan, Iyad, Tabarés-Seisdedos, Rafael, Tabuchi, Takahiro, Tadakamadla, Santosh Kumar, Taherkhani, Amir, Tamiru, Animut Tagele, Tareque, Md Ismail, Thankappan, Kavumpurathu Raman, Thapar, Rekha, Thomas, Nihal, Titova, Mariya Vladimirovna, Tonelli, Marcello, Tovani-Palone, Marcos Roberto, Tran, Bach Xuan, Travillian, Ravensara S, Tsai, Alexander C, Tsatsakis, Aristidis, Tudor Car, Lorainne, Uddin, Riaz, Unim, Brigid, Unnikrishnan, Bhaskaran, Upadhyay, Era, Vacante, Marco, Valadan Tahbaz, Sahel, Valdez, Pascual R, Varughese, Santosh, Vasankari, Tommi Juhani, Venketasubramanian, Narayanaswamy, Villeneuve, Paul J, Violante, Francesco S, Vlassov, Vasily, Vos, Theo, Vu, Giang Thu, Waheed, Yasir, Wamai, Richard G, Wang, Yafeng, Wang, Yanzhong, Wang, Yuan-Pang, Westerman, Ronny, Wickramasinghe, Nuwan Darshana, Wu, Ai-Min, Wu, Chenkai, Yahyazadeh Jabbari, Seyed Hossein, Yamagishi, Kazumasa, Yano, Yuichiro, Yaya, Sanni, Yazdi-Feyzabadi, Vahid, Yeshitila, Yordanos Gizachew, Yip, Paul, Yonemoto, Naohiro, Yoon, Seok-Jun, Younis, Mustafa Z, Yousefinezhadi, Taraneh, Yu, Chuanhua, Yu, Yong, Yuce, Deniz, Zaidi, Syed Saoud, Zaman, Sojib Bin, Zamani, Mohammad, Zamanian, Maryam, Zarafshan, Hadi, Zarei, Ahmad, Zastrozhin, Mikhail Sergeevich, Zhang, Yunquan, Zhang, Zhi-Jiang, Zhao, Xiu-Ju George, Zhu, Cong, Patton, George C, and Viner, Russell M

Published
2021
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83. Global, regional, and national burden of stroke and its risk factors, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019

Author

Feigin, Valery L, Stark, Benjamin A, Johnson, Catherine Owens, Roth, Gregory A, Bisignano, Catherine, Abady, Gdiom Gebreheat, Abbasifard, Mitra, Abbasi-Kangevari, Mohsen, Abd-Allah, Foad, Abedi, Vida, Abualhasan, Ahmed, Abu-Rmeileh, Niveen ME, Abushouk, Abdelrahman I, Adebayo, Oladimeji M, Agarwal, Gina, Agasthi, Pradyumna, Ahinkorah, Bright Opoku, Ahmad, Sohail, Ahmadi, Sepideh, Ahmed Salih, Yusra, Aji, Budi, Akbarpour, Samaneh, Akinyemi, Rufus Olusola, Al Hamad, Hanadi, Alahdab, Fares, Alif, Sheikh Mohammad, Alipour, Vahid, Aljunid, Syed Mohamed, Almustanyir, Sami, Al-Raddadi, Rajaa M, Al-Shahi Salman, Rustam, Alvis-Guzman, Nelson, Ancuceanu, Robert, Anderlini, Deanna, Anderson, Jason A, Ansar, Adnan, Antonazzo, Ippazio Cosimo, Arabloo, Jalal, Ärnlöv, Johan, Artanti, Kurnia Dwi, Aryan, Zahra, Asgari, Samaneh, Ashraf, Tahira, Athar, Mohammad, Atreya, Alok, Ausloos, Marcel, Baig, Atif Amin, Baltatu, Ovidiu Constantin, Banach, Maciej, Barboza, Miguel A, Barker-Collo, Suzanne Lyn, Bärnighausen, Till Winfried, Barone, Mark Thomaz Ugliara, Basu, Sanjay, Bazmandegan, Gholamreza, Beghi, Ettore, Beheshti, Mahya, Béjot, Yannick, Bell, Arielle Wilder, Bennett, Derrick A, Bensenor, Isabela M, Bezabhe, Woldesellassie Mequanint, Bezabih, Yihienew Mequanint, Bhagavathula, Akshaya Srikanth, Bhardwaj, Pankaj, Bhattacharyya, Krittika, Bijani, Ali, Bikbov, Boris, Birhanu, Mulugeta M, Boloor, Archith, Bonny, Aime, Brauer, Michael, Brenner, Hermann, Bryazka, Dana, Butt, Zahid A, Caetano dos Santos, Florentino Luciano, Campos-Nonato, Ismael R, Cantu-Brito, Carlos, Carrero, Juan J, Castañeda-Orjuela, Carlos A, Catapano, Alberico L, Chakraborty, Promit Ananyo, Charan, Jaykaran, Choudhari, Sonali Gajanan, Chowdhury, Enayet Karim, Chu, Dinh-Toi, Chung, Sheng-Chia, Colozza, David, Costa, Vera Marisa, Costanzo, Simona, Criqui, Michael H, Dadras, Omid, Dagnew, Baye, Dai, Xiaochen, Dalal, Koustuv, Damasceno, Albertino Antonio Moura, D'Amico, Emanuele, Dandona, Lalit, Dandona, Rakhi, Darega Gela, Jiregna, Davletov, Kairat, De la Cruz-Góngora, Vanessa, Desai, Rupak, Dhamnetiya, Deepak, Dharmaratne, Samath Dhamminda, Dhimal, Mandira Lamichhane, Dhimal, Meghnath, Diaz, Daniel, Dichgans, Martin, Dokova, Klara, Doshi, Rajkumar, Douiri, Abdel, Duncan, Bruce B, Eftekharzadeh, Sahar, Ekholuenetale, Michael, El Nahas, Nevine, Elgendy, Islam Y, Elhadi, Muhammed, El-Jaafary, Shaimaa I, Endres, Matthias, Endries, Aman Yesuf, Erku, Daniel Asfaw, Faraon, Emerito Jose A, Farooque, Umar, Farzadfar, Farshad, Feroze, Abdullah Hamid, Filip, Irina, Fischer, Florian, Flood, David, Gad, Mohamed M, Gaidhane, Shilpa, Ghanei Gheshlagh, Reza, Ghashghaee, Ahmad, Ghith, Nermin, Ghozali, Ghozali, Ghozy, Sherief, Gialluisi, Alessandro, Giampaoli, Simona, Gilani, Syed Amir, Gill, Paramjit Singh, Gnedovskaya, Elena V, Golechha, Mahaveer, Goulart, Alessandra C, Guo, Yuming, Gupta, Rajeev, Gupta, Veer Bala, Gupta, Vivek Kumar, Gyanwali, Pradip, Hafezi-Nejad, Nima, Hamidi, Samer, Hanif, Asif, Hankey, Graeme J, Hargono, Arief, Hashi, Abdiwahab, Hassan, Treska S, Hassen, Hamid Yimam, Havmoeller, Rasmus J, Hay, Simon I, Hayat, Khezar, Hegazy, Mohamed I, Herteliu, Claudiu, Holla, Ramesh, Hostiuc, Sorin, Househ, Mowafa, Huang, Junjie, Humayun, Ayesha, Hwang, Bing-Fang, Iacoviello, Licia, Iavicoli, Ivo, Ibitoye, Segun Emmanuel, Ilesanmi, Olayinka Stephen, Ilic, Irena M, Ilic, Milena D, Iqbal, Usman, Irvani, Seyed Sina Naghibi, Islam, Sheikh Mohammed Shariful, Ismail, Nahlah Elkudssiah, Iso, Hiroyasu, Isola, Gaetano, Iwagami, Masao, Jacob, Louis, Jain, Vardhmaan, Jang, Sung-In, Jayapal, Sathish Kumar, Jayaram, Shubha, Jayawardena, Ranil, Jeemon, Panniyammakal, Jha, Ravi Prakash, Johnson, Walter D, Jonas, Jost B, Joseph, Nitin, Jozwiak, Jacek Jerzy, Jürisson, Mikk, Kalani, Rizwan, Kalhor, Rohollah, Kalkonde, Yogeshwar, Kamath, Ashwin, Kamiab, Zahra, Kanchan, Tanuj, Kandel, Himal, Karch, André, Katoto, Patrick DMC, Kayode, Gbenga A, Keshavarz, Pedram, Khader, Yousef Saleh, Khan, Ejaz Ahmad, Khan, Imteyaz A, Khan, Maseer, Khan, Moien AB, Khatib, Mahalaqua Nazli, Khubchandani, Jagdish, Kim, Gyu Ri, Kim, Min Seo, Kim, Yun Jin, Kisa, Adnan, Kisa, Sezer, Kivimäki, Mika, Kolte, Dhaval, Koolivand, Ali, Koulmane Laxminarayana, Sindhura Lakshmi, Koyanagi, Ai, Krishan, Kewal, Krishnamoorthy, Vijay, Krishnamurthi, Rita V, Kumar, G Anil, Kusuma, Dian, La Vecchia, Carlo, Lacey, Ben, Lak, Hassan Mehmood, Lallukka, Tea, Lasrado, Savita, Lavados, Pablo M, Leonardi, Matilde, Li, Bingyu, Li, Shanshan, Lin, Hualiang, Lin, Ro-Ting, Liu, Xuefeng, Lo, Warren David, Lorkowski, Stefan, Lucchetti, Giancarlo, Lutzky Saute, Ricardo, Magdy Abd El Razek, Hassan, Magnani, Francesca Giulia, Mahajan, Preetam Bhalchandra, Majeed, Azeem, Makki, Alaa, Malekzadeh, Reza, Malik, Ahmad Azam, Manafi, Navid, Mansournia, Mohammad Ali, Mantovani, Lorenzo Giovanni, Martini, Santi, Mazzaglia, Giampiero, Mehndiratta, Man Mohan, Menezes, Ritesh G, Meretoja, Atte, Mersha, Amanual Getnet, Miao Jonasson, Junmei, Miazgowski, Bartosz, Miazgowski, Tomasz, Michalek, Irmina Maria, Mirrakhimov, Erkin M, Mohammad, Yousef, Mohammadian-Hafshejani, Abdollah, Mohammed, Shafiu, Mokdad, Ali H, Mokhayeri, Yaser, Molokhia, Mariam, Moni, Mohammad Ali, Montasir, Ahmed Al, Moradzadeh, Rahmatollah, Morawska, Lidia, Morze, Jakub, Muruet, Walter, Musa, Kamarul Imran, Nagarajan, Ahamarshan Jayaraman, Naghavi, Mohsen, Narasimha Swamy, Sreenivas, Nascimento, Bruno Ramos, Negoi, Ruxandra Irina, Neupane Kandel, Sandhya, Nguyen, Trang Huyen, Norrving, Bo, Noubiap, Jean Jacques, Nwatah, Vincent Ebuka, Oancea, Bogdan, Odukoya, Oluwakemi Ololade, Olagunju, Andrew T, Orru, Hans, Owolabi, Mayowa O, Padubidri, Jagadish Rao, Pana, Adrian, Parekh, Tarang, Park, Eun-Cheol, Pashazadeh Kan, Fatemeh, Pathak, Mona, Peres, Mario F P, Perianayagam, Arokiasamy, Pham, Truong-Minh, Piradov, Michael A, Podder, Vivek, Polinder, Suzanne, Postma, Maarten J, Pourshams, Akram, Radfar, Amir, Rafiei, Alireza, Raggi, Alberto, Rahim, Fakher, Rahimi-Movaghar, Vafa, Rahman, Mosiur, Rahman, Muhammad Aziz, Rahmani, Amir Masoud, Rajai, Nazanin, Ranasinghe, Priyanga, Rao, Chythra R, Rao, Sowmya J, Rathi, Priya, Rawaf, David Laith, Rawaf, Salman, Reitsma, Marissa B, Renjith, Vishnu, Renzaho, Andre M N, Rezapour, Aziz, Rodriguez, Jefferson Antonio Buendia, Roever, Leonardo, Romoli, Michele, Rynkiewicz, Andrzej, Sacco, Simona, Sadeghi, Masoumeh, Saeedi Moghaddam, Sahar, Sahebkar, Amirhossein, Saif-Ur-Rahman, KM, Salah, Rehab, Samaei, Mehrnoosh, Samy, Abdallah M, Santos, Itamar S, Santric-Milicevic, Milena M, Sarrafzadegan, Nizal, Sathian, Brijesh, Sattin, Davide, Schiavolin, Silvia, Schlaich, Markus P, Schmidt, Maria Inês, Schutte, Aletta Elisabeth, Sepanlou, Sadaf G, Seylani, Allen, Sha, Feng, Shahabi, Saeed, Shaikh, Masood Ali, Shannawaz, Mohammed, Shawon, Md Shajedur Rahman, Sheikh, Aziz, Sheikhbahaei, Sara, Shibuya, Kenji, Siabani, Soraya, Silva, Diego Augusto Santos, Singh, Jasvinder A, Singh, Jitendra Kumar, Skryabin, Valentin Yurievich, Skryabina, Anna Aleksandrovna, Sobaih, Badr Hasan, Stortecky, Stefan, Stranges, Saverio, Tadesse, Eyayou Girma, Tarigan, Ingan Ukur, Temsah, Mohamad-Hani, Teuschl, Yvonne, Thrift, Amanda G, Tonelli, Marcello, Tovani-Palone, Marcos Roberto, Tran, Bach Xuan, Tripathi, Manjari, Tsegaye, Gebiyaw Wudie, Ullah, Anayat, Unim, Brigid, Unnikrishnan, Bhaskaran, Vakilian, Alireza, Valadan Tahbaz, Sahel, Vasankari, Tommi Juhani, Venketasubramanian, Narayanaswamy, Vervoort, Dominique, Vo, Bay, Volovici, Victor, Vosoughi, Kia, Vu, Giang Thu, Vu, Linh Gia, Wafa, Hatem A, Waheed, Yasir, Wang, Yanzhong, Wijeratne, Tissa, Winkler, Andrea Sylvia, Wolfe, Charles D A, Woodward, Mark, Wu, Jason H, Wulf Hanson, Sarah, Xu, Xiaoyue, Yadav, Lalit, Yadollahpour, Ali, Yahyazadeh Jabbari, Seyed Hossein, Yamagishi, Kazumasa, Yatsuya, Hiroshi, Yonemoto, Naohiro, Yu, Chuanhua, Yunusa, Ismaeel, Zaman, Muhammed Shahriar, Zaman, Sojib Bin, Zamanian, Maryam, Zand, Ramin, Zandifar, Alireza, Zastrozhin, Mikhail Sergeevich, Zastrozhina, Anasthasia, Zhang, Yunquan, Zhang, Zhi-Jiang, Zhong, Chenwen, Zuniga, Yves Miel H, and Murray, Christopher J L

Published
2021
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84. Design and evaluation of vertical cup metering mechanism for urea briquette application

Author

MAN MOHAN DEO, DIPANKAR DE, INDRA MANI, and MIR ASIF IQUEBAL

Subjects
Metering device, Miss index, Multiple index, Precision, Urea briquettes., Agriculture
Abstract

Vertical cup feed metering device was designed and evaluated at Division of Agricultural Engineering, ICARIARI, New Delhi during 2013-14 for singulation and uniform placement of urea briquettes in two forms, viz. UB1 (3 g) and UB2 (2 g). Performance parameters like average spacing, multiple index, missing index, quality feed index and precision were measured. The metering device was tested for different cup size depth of 6.5mm (CS1), 3.5mm (CS2) and 2.5 mm (CS3) with hemi-spherical shape. The average spacing was significantly (P

Published
2022
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85. Mapping development and health effects of cooking with solid fuels in low-income and middle-income countries, 2000–18: a geospatial modelling study

Author

Joseph Jon Frostad, QuynhAnh P Nguyen, Mathew M Baumann, Brigette F Blacker, Laurie B Marczak, Aniruddha Deshpande, Kirsten E Wiens, Kate E LeGrand, Kimberly B Johnson, Mohsen Abbasi-Kangevari, Amir Abdoli, Hassan Abolhassani, Lucas Guimarães Abreu, Michael R M Abrigo, Niveen ME Abu-Rmeileh, Victor Adekanmbi, Anurag Agrawal, Muktar Beshir Ahmed, Ziyad Al-Aly, Fahad Mashhour Alanezi, Jacqueline Elizabeth Alcalde-Rabanal, Vahid Alipour, Khalid A Altirkawi, Nelson Alvis-Guzman, Nelson J Alvis-Zakzuk, Adeladza Kofi Amegah, Saeed Amini, Fatemeh Amiri, Dickson A Amugsi, Robert Ancuceanu, Catalina Liliana Andrei, Tudorel Andrei, Ernoiz Antriyandarti, Davood Anvari, Jalal Arabloo, Morteza Arab-Zozani, Seyyed Shamsadin Athari, Marcel Ausloos, Getinet Ayano, Yared Asmare Aynalem, Samad Azari, Ashish D Badiye, Atif Amin Baig, Kalpana Balakrishnan, Maciej Banach, Sanjay Basu, Neeraj Bedi, Michelle L Bell, Derrick A Bennett, Krittika Bhattacharyya, Zulfiqar A Bhutta, Sadia Bibi, Somayeh Bohlouli, Soufiane Boufous, Nicola Luigi Bragazzi, Dejana Braithwaite, Sharath Burugina Nagaraja, Zahid A Butt, Florentino Luciano Caetano dos Santos, Josip Car, Rosario Cárdenas, Felix Carvalho, Joao Mauricio Castaldelli-Maia, Carlos A Castañeda-Orjuela, Ester Cerin, Soosanna Kumary Chattu, Vijay Kumar Chattu, Pankaj Chaturvedi, Sarika Chaturvedi, Simiao Chen, Dinh-Toi Chu, Sheng-Chia Chung, Saad M A Dahlawi, Giovanni Damiani, Lalit Dandona, Rakhi Dandona, Aso Mohammad Darwesh, Jai K Das, Aditya Prasad Dash, Claudio Alberto Dávila-Cervantes, Diego De Leo, Jan-Walter De Neve, Getu Debalkie Demissie, Edgar Denova-Gutiérrez, Sagnik Dey, Samath Dhamminda Dharmaratne, Meghnath Dhimal, Govinda Prasad Dhungana, Daniel Diaz, Isaac Oluwafemi Dipeolu, Fariba Dorostkar, Leila Doshmangir, Andre Rodrigues Duraes, Hisham Atan Edinur, Ferry Efendi, Maha El Tantawi, Sharareh Eskandarieh, Ibtihal Fadhil, Nazir Fattahi, Nelsensius Klau Fauk, Seyed-Mohammad Fereshtehnejad, Morenike Oluwatoyin Folayan, Masoud Foroutan, Takeshi Fukumoto, Abhay Motiramji Gaidhane, Mansour Ghafourifard, Ahmad Ghashghaee, Syed Amir Gilani, Tiffany K Gill, Alessandra C Goulart, Bárbara Niegia Garcia Goulart, Ayman Grada, Mohammed Ibrahim Mohialdeen Gubari, Davide Guido, Yuming Guo, Rajat Das Gupta, Rajeev Gupta, Reyna Alma Gutiérrez, Nima Hafezi-Nejad, Randah R Hamadeh, Ahmed I Hasaballah, Soheil Hassanipour, Khezar Hayat, Behzad Heibati, Reza Heidari-Soureshjani, Nathaniel J Henry, Claudiu Herteliu, Mehdi Hosseinzadeh, Mohamed Hsairi, Guoqing Hu, Segun Emmanuel Ibitoye, Olayinka Stephen Ilesanmi, Irena M Ilic, Milena D Ilic, Seyed Sina Naghibi Irvani, Sheikh Mohammed Shariful Islam, Chidozie C D Iwu, Jalil Jaafari, Mihajlo Jakovljevic, Tahereh Javaheri, Ravi Prakash Jha, John S Ji, Jost B Jonas, Ali Kabir, Zubair Kabir, Rohollah Kalhor, Naser Kamyari, Tanuj Kanchan, Umesh Kapil, Neeti Kapoor, Gbenga A Kayode, Peter Njenga Keiyoro, Yousef Saleh Khader, Nauman Khalid, Ejaz Ahmad Khan, Maseer Khan, Md Nuruzzaman Khan, Khaled Khatab, Mona M Khater, Mahalaqua Nazli Khatib, Maryam Khayamzadeh, Jagdish Khubchandani, Gyu Ri Kim, Yun Jin Kim, Ruth W Kimokoti, Adnan Kisa, Sezer Kisa, Luke D Knibbs, Parvaiz A Koul, Ai Koyanagi, Kewal Krishan, G Anil Kumar, Manasi Kumar, Dian Kusuma, Carlo La Vecchia, Ben Lacey, Faris Hasan Lami, Qing Lan, Savita Lasrado, Paolo Lauriola, Paul H Lee, Sonia Lewycka, Shanshan Li, Daiane Borges Machado, Phetole Walter Mahasha, Mina Maheri, Azeem Majeed, Afshin Maleki, Reza Malekzadeh, Deborah Carvalho Malta, Borhan Mansouri, Mohammad Ali Mansournia, Natalie Maria Martinez, Santi Martini, Francisco Rogerlândio Martins-Melo, Benjamin K Mayala, Man Mohan Mehndiratta, Walter Mendoza, Ritesh G Menezes, Endalkachew Worku Mengesha, Tuomo J Meretoja, Tomislav Mestrovic, Irmina Maria Michalek, Erkin M Mirrakhimov, Maryam Mirzaei, Roya Mirzaei, Babak Moazen, Yousef Mohammad, Abdollah Mohammadian-Hafshejani, Shafiu Mohammed, Ali H Mokdad, Lorenzo Monasta, Maziar Moradi-Lakeh, Paula Moraga, Lidia Morawska, Abbas Mosapour, Simin Mouodi, Amin Mousavi Khaneghah, Satinath Mukhopadhyay, Sandra B Munro, Christopher J L Murray, Ahamarshan Jayaraman Nagarajan, Mohsen Naghavi, Sanjeev Nair, Vinay Nangia, Bruno Ramos Nascimento, Javad Nazari, Ionut Negoi, Henok Biresaw Netsere, Josephine W Ngunjiri, Huong Lan Thi Nguyen, Jean Jacques Noubiap, Bogdan Oancea, Felix Akpojene Ogbo, In-Hwan Oh, Andrew T Olagunju, Bolajoko Olubukunola Olusanya, Jacob Olusegun Olusanya, Ahmed Omar Bali, Obinna E Onwujekwe, Nikita Otstavnov, Stanislav S Otstavnov, Mayowa O Owolabi, Mahesh P A, Anamika Pandey, Eun-Cheol Park, Eun-Kee Park, Sangram Kishor Patel, Hai Quang Pham, Thomas Pilgrim, Meghdad Pirsaheb, Khem Narayan Pokhrel, Maarten J Postma, Zahiruddin Quazi Syed, Navid Rabiee, Amir Radfar, Fakher Rahim, Mohammad Hifz Ur Rahman, Muhammad Aziz Rahman, Amir Masoud Rahmani, Chhabi Lal Ranabhat, Sowmya J Rao, Davide Rasella, Prateek Rastogi, Goura Kishor Rath, David Laith Rawaf, Salman Rawaf, Lal Rawal, Reza Rawassizadeh, Andre M N Renzaho, Bhageerathy Reshmi, Negar Rezaei, Nima Rezaei, Aziz Rezapour, Jennifer Rickard, Leonardo Roever, Luca Ronfani, Morteza Rostamian, Enrico Rubagotti, Godfrey M Rwegerera, Basema Saddik, Ehsan Sadeghi, Sahar Saeedi Moghaddam, Rajesh Sagar, Amirhossein Sahebkar, Biniyam Sahiledengle, Marwa Rashad Salem, Abdallah M Samy, Milena M Santric-Milicevic, Sivan Yegnanarayana Iyer Saraswathy, Brijesh Sathian, Thirunavukkarasu Sathish, David C Schwebel, Sadaf G Sepanlou, Saeed Shahabi, Amira A Shaheen, Izza Shahid, Masood Ali Shaikh, Ali S Shalash, Mehran Shams-Beyranvand, Mohammed Shannawaz, Kiomars Sharafi, Aziz Sheikh, Sara Sheikhbahaei, Ranjitha S Shetty, Wondimeneh Shibabaw Shiferaw, Mika Shigematsu, Jae Il Shin, K M Shivakumar, Soraya Siabani, Tariq Jamal Siddiqi, Balbir Bagicha Singh, Jasvinder A Singh, Yitagesu Sintayehu, Muluken Bekele Sorrie, Ireneous N Soyiri, Emma Elizabeth Spurlock, Chandrashekhar T Sreeramareddy, Leo Stockfelt, Mu'awiyyah Babale Sufiyan, Rizwan Suliankatchi Abdulkader, Rafael Tabarés-Seisdedos, Takahiro Tabuchi, Amir Taherkhani, Mohamad-Hani Temsah, Kavumpurathu Raman Thankappan, Marcos Roberto Tovani-Palone, Eugenio Traini, Saif Ullah, Bhaskaran Unnikrishnan, Era Upadhyay, Sahel Valadan Tahbaz, Santosh Varughese, Francesco S Violante, Bay Vo, Giang Thu Vu, Yasir Waheed, Yuan-Pang Wang, Catherine A Welgan, Andrea Werdecker, Seyed Hossein Yahyazadeh Jabbari, Sanni Yaya, Vahid Yazdi-Feyzabadi, Mekdes Tigistu Yilma, Naohiro Yonemoto, Mustafa Z Younis, Taraneh Yousefinezhadi, Chuanhua Yu, Yong Yu, Sojib Bin Zaman, Yunquan Zhang, Zhi-Jiang Zhang, Michael Brauer, Simon I Hay, and Robert C Reiner, Jr

Subjects
Public aspects of medicine, RA1-1270
Abstract

Summary: Background: More than 3 billion people do not have access to clean energy and primarily use solid fuels to cook. Use of solid fuels generates household air pollution, which was associated with more than 2 million deaths in 2019. Although local patterns in cooking vary systematically, subnational trends in use of solid fuels have yet to be comprehensively analysed. We estimated the prevalence of solid-fuel use with high spatial resolution to explore subnational inequalities, assess local progress, and assess the effects on health in low-income and middle-income countries (LMICs) without universal access to clean fuels. Methods: We did a geospatial modelling study to map the prevalence of solid-fuel use for cooking at a 5 km × 5 km resolution in 98 LMICs based on 2·1 million household observations of the primary cooking fuel used from 663 population-based household surveys over the years 2000 to 2018. We use observed temporal patterns to forecast household air pollution in 2030 and to assess the probability of attaining the Sustainable Development Goal (SDG) target indicator for clean cooking. We aligned our estimates of household air pollution to geospatial estimates of ambient air pollution to establish the risk transition occurring in LMICs. Finally, we quantified the effect of residual primary solid-fuel use for cooking on child health by doing a counterfactual risk assessment to estimate the proportion of deaths from lower respiratory tract infections in children younger than 5 years that could be associated with household air pollution. Findings: Although primary reliance on solid-fuel use for cooking has declined globally, it remains widespread. 593 million people live in districts where the prevalence of solid-fuel use for cooking exceeds 95%. 66% of people in LMICs live in districts that are not on track to meet the SDG target for universal access to clean energy by 2030. Household air pollution continues to be a major contributor to particulate exposure in LMICs, and rising ambient air pollution is undermining potential gains from reductions in the prevalence of solid-fuel use for cooking in many countries. We estimated that, in 2018, 205 000 (95% uncertainty interval 147 000–257 000) children younger than 5 years died from lower respiratory tract infections that could be attributed to household air pollution. Interpretation: Efforts to accelerate the adoption of clean cooking fuels need to be substantially increased and recalibrated to account for subnational inequalities, because there are substantial opportunities to improve air quality and avert child mortality associated with household air pollution. Funding: Bill & Melinda Gates Foundation.

Published
2022
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89. Contributors

Author

Abd-Elsalam, Kamel A., primary, Ahmed, Farah K., additional, Ai, Chongyang, additional, Akmal, Hasnain, additional, Alula, Melisew Tadele, additional, Annamalai, Jayshree, additional, Aragaw, Belete Asefa, additional, Banerjee, Kangkana, additional, Bedlovičová, Zdenka, additional, Behera, Anindita, additional, Bhagavanth Reddy, G., additional, Bhatt, Pankaj, additional, Boopathy, Usharani, additional, Borsarelli, Claudio Darío, additional, Cisneros, Ana Belén, additional, Cuozzo, Sergio, additional, Dam, Paulami, additional, Dhulappa, Awalagaway, additional, Diez, María Cristina, additional, Divya Mohan, R., additional, Farheen, Asma, additional, Fatouh Hamed, Said, additional, Gacem, Mohamed Amine, additional, Gallucci, Mauro Nicolás, additional, George, Bini, additional, Gutierrez, Leonardo, additional, Hashim, Ayat F., additional, Jalal, Husna, additional, Jane Cypriyana, P.J., additional, Jenifer Selvarani, A., additional, Jiang, Chunmei, additional, Karam, Kashmala, additional, Khan, Mubarak Ali, additional, Khan, Muhammad Saleem, additional, Khan, Tariq, additional, Kim, Beom Soo, additional, King'ondu, Cecil K., additional, Kishore Kumar, K., additional, Majoni, Stephen, additional, Mandal, Amit Kumar, additional, Manikandan, Murugesan, additional, Maqsud, Muhammad Shahroz, additional, Mariadoss, Arokia Vijaya Anand, additional, Mhlanga, Sabelo D., additional, Mondal, Rittick, additional, Mudila, Harish, additional, Murugan, Karuvelan, additional, Murugan, Kasi, additional, Narasimha, G., additional, Narsing Rao, Manik Prabhu, additional, Nthunya, Lebea N., additional, Olenin, Andrei Yu., additional, Paulkumar, Kanniah, additional, Pieretti, Joana Claudio, additional, Ponnaiah, Paulraj, additional, Pradhan, Sweta Priyadarshini, additional, Prasher, Parteek, additional, Purayil, Sajna Keeyari, additional, Purkayastha, Debraj Dhar, additional, Ravishankar Rai, V., additional, Rey, Valentina, additional, Richards, Heidi L., additional, Rubilar, Olga, additional, Saha, Pathikrit, additional, Saigeetha, S., additional, Salama, Heba H., additional, Sambhudevan, Sreedha, additional, Samrot, Antony V., additional, Saravanakumar, Kandasamy, additional, Sathiyaseelan, Anbazhagan, additional, Seabra, Amedea Barozzi, additional, Seku, Kondaiah, additional, Shajahan, Azeez, additional, Shalaby, Emad A., additional, Shanmugam, Jayashree, additional, Sharma, Mousmee, additional, Sharma, Mukti, additional, Shi, Junling, additional, Shyam, Aswathi, additional, Smitha Chandran, S., additional, Some, Sudip, additional, Srivastava, Man Mohan, additional, Srivastava, Shalini, additional, Tortella, Gonzalo, additional, Tulli, Fiorella, additional, Turbay, María Beatriz Espeche, additional, Tyagi, Ranjini, additional, Umar, Ali, additional, Vasil'kov, Alexander Yu., additional, Verma, Amit, additional, Wang, Myeong-Hyeon, additional, Xu, Xiaoguang, additional, Yan, Lu, additional, and Zhao, Xixi, additional

Published
2022
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92. Control químico de Fusariosis de la espiga del trigo y su efecto sobre los componentes de producción y calidad de granos

Author

Ruth Fabiola Scholz, Lidia Quintana, Aldo Ortiz, and Man Mohan Kohli

Subjects
triticum aestivum, fusarium graminearum, fungicidas, deoxynivalenol, Agriculture
Abstract

La fusariosis de la espiga del trigo (FET) producida principalmente por Fusarium graminearum, es una de las enfermedades más importantes para la producción del trigo en Paraguay, no solo por las pérdidas de rendimiento que ocasionan sino por la presencia de micotoxinas en granos. El objetivo del experimento fue evaluar distintos grupos químicos de fungicidas y sus mezclas para el control de FET y su relación con el rendimiento y niveles de micotoxina dioxinivalenol (DON) en granos de trigo. Los fungicidas fueron aplicados en tres estados de desarrollo del cultivo: espigazón, antesis y grano lechoso en la variedad Canindé 13. Todos los fungicidas evaluados (Tebuconazole, Metconazole + Epoxiconazole, Azoxystrobin, Fluxapyroxad + Epoxyconazole + Pyraclostrobin, Azoxystrobin + Benzovindiflupir) disminuyeron significativamente en promedio los niveles de índice de infección del FET y aumentaron el rendimiento y peso de mil granos comparados al testigo sin control químico. La mayoría de los tratamientos que incluyeron estrobilurinas en su composición resultaron con los niveles más altos de DON (4,07-4,27 ppm) en granos de trigo. Entre los fungicidas evaluados, el Tebuconazole presentó el menor (1-1.5 ppm) nivel de concentración de DON en granos.

Published
2021
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93. Assessing community knowledge, attitude and practices to strengthen communication strategy for Malaria Elimination Demonstration Project in Mandla

Author

Harsh Rajvanshi, Kalyan B. Saha, Ravendra K. Sharma, Praveen K. Bharti, Sekh Nisar, Himanshu Jayswar, Ashok K. Mishra, Man Mohan Shukla, Aparup Das, Harpreet Kaur, Suman L. Wattal, and Altaf A. Lal

Subjects
Arctic medicine. Tropical medicine, RC955-962, Infectious and parasitic diseases, RC109-216
Abstract

Abstract Background Changes in social, belief, and behavioural practices are essential for the success of any public health delivery programme. In the planning stages of the Malaria Elimination Demonstration Project (MEDP), priority was given to communication with a goal to develop capacity of health workers and to improve the knowledge, attitude and practices (KAP) of the people of Mandla. This paper describes the level of community knowledge on malaria, including its prevention, diagnosis, treatment-seeking behaviour, and the level of satisfaction with the services provided by the project. Methods A cross sectional survey was undertaken in 1233 villages of Mandla to study the KAP and self-assessed improvement in knowledge and satisfaction level of the community. The goal of the study was to understand whether there is need for strengthening communication strategy of MEDP for better impact. The survey was conducted amongst the head/eligible members of the 733 households located in the nine blocks of the district using clustered random sampling. Results Though four-fifths of the respondents were able to correlate the transmission of malaria with mosquitoes, misconceptions existed among them. The types of malaria were not known to everyone. Only 39% were aware of the Indoor Residual Spray (IRS) and 41% understood the value of Long-Lasting Insecticidal Nets (LLIN). Around 71% of subjects surveyed were aware of the proper diagnostic tests for malaria. A total of 87% of the respondents knew about the MEDP staff working in their respective villages. Conclusion The study reported gaps in knowledge on malaria at community level. The self-assessment of the community revealed that the communication strategy established by MEDP in Mandla district has been useful to them as they are becoming better informed about the prevention and treatment aspects of disease. The lessons learned as revealed in the KAP survey will improve malaria elimination outcomes in a timely manner.

Published
2021
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94. El impacto de las enfermedades fúngicas en el cultivo de soja (Glycine max) en Paraguay ¿es posible estimar las pérdidas?

Author

Andrea Alejandra Arrua, Horacio D. Lopez-Nicora, Danilo Fernández Ríos, Cristhian Javier Grabowski, Cinthia Cazal-Martínez, and Man Mohan Kohli

Subjects
cultivos extensivos, epifitias, enfermedades fungicas, paraguay, perdidas, Social Sciences, Education, Technology, Medicine
Abstract

La economía del Paraguay es altamente dependiente de la producción agrícola, en especial de la soja (Glycine max), por tanto, todo aquello que represente un riesgo para este cultivo es un asunto prioritario para el país. Las fuentes principales de riesgo en la agricultura derivan de los impactos en la producción por el clima, plagas y otros factores en precios y en el contexto institucional y político. La estimación de las pérdidas de los cultivos es fundamental, ya que cuantificar los daños y compararlos con los umbrales económicos permite una adecuada toma de decisiones, determinando si un tratamiento es o no necesario y cuándo; qué se hará el próximo año agrícola, la selección de las variedades, el tipo de manejo que se hará de las enfermedades, entre otros. Considerando que los agentes fúngicos pueden resultar una amenaza para la producción, el objeto de esta revisión fue determinar si existen de manera pública datos para estimar pérdidas a causa de enfermedades fúngicas en soja (G. max). Se concluye que con la información disponible actualmente no es posible determinar estimar las pérdidas y se visualiza la necesidad de generar datos válidos y fidedignos, además de realizar un trabajo coordinado entre productores, industria, gobierno y la academia.

Published
2021
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95. K63-linked ubiquitination of DYRK1A by TRAF2 alleviates Sprouty 2-mediated degradation of EGFR

Author

Pengshan Zhang, Zhe Zhang, Yinkun Fu, Ying Zhang, Michael P. Washburn, Laurence Florens, Min Wu, Chen Huang, Zhaoyuan Hou, and Man Mohan

Subjects
Cytology, QH573-671
Abstract

Abstract Dual specificity tyrosine phosphorylation regulated kinase 1A, DYRK1A, functions in multiple cellular pathways, including signaling, endocytosis, synaptic transmission, and transcription. Alterations in dosage of DYRK1A leads to defects in neurogenesis, cell growth, and differentiation, and may increase the risk of certain cancers. DYRK1A localizes to a number of subcellular structures including vesicles where it is known to phosphorylate a number of proteins and regulate vesicle biology. However, the mechanism by which it translocates to vesicles is poorly understood. Here we report the discovery of TRAF2, an E3 ligase, as an interaction partner of DYRK1A. Our data suggest that TRAF2 binds to PVQE motif residing in between the PEST and histidine repeat domain (HRD) of DYRK1A protein, and mediates K63-linked ubiquitination of DYRK1A. This results in translocation of DYRK1A to the vesicle membrane. DYRK1A increases phosphorylation of Sprouty 2 on vesicles, leading to the inhibition of EGFR degradation, and depletion of TRAF2 expression accelerates EGFR degradation. Further, silencing of DYRK1A inhibits the growth of glioma cells mediated by TRAF2. Collectively, these findings suggest that the axis of TRAF2–DYRK1A-Sprouty 2 can be a target for new therapeutic development for EGFR-mediated human pathologies.

Published
2021
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96. The international league against epilepsy primary healthcare educational curriculum: Assessment of educational needs

Author

Singh, Gagandeep, Braga, Patricia, Carrizosa, Jaime, Prevos‐Morgant, Marielle, Mehndiratta, Man Mohan, Shisler, Priscilla, Triki, Chahnez, Wiebe, Samuel, Wilmshurst, Jo, and Blümcke, Ingmar

Abstract

To assess the need for an epilepsy educational curriculum for primary healthcare providers formulated by the International League Against Epilepsy (ILAE) and the importance attributed to its competencies by epilepsy specialists and primary care providers and across country‐income settings. The ILAE primary care epilepsy curriculum was translated to five languages. A structured questionnaire assessing the importance of its 26 curricular competencies was posted online and publicized widely to an international community. Respondents included epilepsy specialists, primary care providers, and others from three World Bank country‐income categories. Responses from different groups were compared with univariate and ordinal logistic regression analyses. Of 785 respondents, 60% noted that a primary care epilepsy curriculum did not exist or they were unaware of one in their country. Median ranks of importance for all competencies were high (very important to extremely important) in the entire sample and across different groups. Fewer primary care providers than specialists rated the following competencies as extremely important: definition of epilepsy (p= .03), recognition of seizure mimics (p= .02), interpretation of test results for epilepsy care (p= .001), identification of drug‐resistant epilepsy (0.005) and management of psychiatric comorbidities (0.05). Likewise, fewer respondents from LMICs in comparison to UMICs rated 15 competencies as extremely important. The survey underscores the unmet need for an epilepsy curriculum in primary care and the relevance of its competencies across different vocational and socioeconomic settings. Differences across vocational and country income groups indicate that educational packages should be developed and adapted to needs in different settings.

Published
2024
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99. Current Trends and Advances in Agricultural Sciences

Author

Varanasi Adarsh, Banojini Parida, Sumana Balo, Rohit Kumar Choudhury, Dibyendu Mukhopadhyay, Aradhana Panda, Ishtiyaq Ahad, Moirangthem Monalisa Devi, Satyabrata Sarangi, Praneswar Ghosh, Anwesha Samanta, Krisanu Golui, Samapriya Saha, Brunda N. B., Chandana S., Mahebub, Vibhishan N. B., Menaka M., Poonam Kumari, Kumari Ruchika, Sunil Kumar, Maheshnaik B. L., Syed Ali, Venkatesh L., Shwetha V. R., G. M. Solanke, S. M. Lokhande, Samiksha More, Manuj Awasthi, Amit Bhatt, Yashowardhan Singh, Likhita J., Meenakshi Arya, Swarna Kurmi, Sujeet Deshmukh, Ranjeet Deshmukh, Aman Deshmukh, Dr. Karan Verma, Dr. Ashish Kumar, Lovepreet Singh, Komal, Shital P. Shinde, Tawale Jayashri B., Rajni Solanki, Priyanka Sharma, Babli, Jainender Bhati, Khushboo Yadav, Dr. B. Spandana, Dr. M. Preethi, M. G. Nandaniya, Bhumi D. Barad, S. R. Patel, Subhajit Mukherjee, Piyush Kumar, Deepshikha Singh, Himanshu Sharma, Minam Gamoh, Man Mohan Deo, Prasoon Verma, Mohammad Hashim, Hemant Kumar, Satyanarayan Soni, Preeti Kumari, Varanasi Adarsh, Banojini Parida, Sumana Balo, Rohit Kumar Choudhury, Dibyendu Mukhopadhyay, Aradhana Panda, Ishtiyaq Ahad, Moirangthem Monalisa Devi, Satyabrata Sarangi, Praneswar Ghosh, Anwesha Samanta, Krisanu Golui, Samapriya Saha, Brunda N. B., Chandana S., Mahebub, Vibhishan N. B., Menaka M., Poonam Kumari, Kumari Ruchika, Sunil Kumar, Maheshnaik B. L., Syed Ali, Venkatesh L., Shwetha V. R., G. M. Solanke, S. M. Lokhande, Samiksha More, Manuj Awasthi, Amit Bhatt, Yashowardhan Singh, Likhita J., Meenakshi Arya, Swarna Kurmi, Sujeet Deshmukh, Ranjeet Deshmukh, Aman Deshmukh, Dr. Karan Verma, Dr. Ashish Kumar, Lovepreet Singh, Komal, Shital P. Shinde, Tawale Jayashri B., Rajni Solanki, Priyanka Sharma, Babli, Jainender Bhati, Khushboo Yadav, Dr. B. Spandana, Dr. M. Preethi, M. G. Nandaniya, Bhumi D. Barad, S. R. Patel, Subhajit Mukherjee, Piyush Kumar, Deepshikha Singh, Himanshu Sharma, Minam Gamoh, Man Mohan Deo, Prasoon Verma, Mohammad Hashim, Hemant Kumar, Satyanarayan Soni, and Preeti Kumari

Abstract

"Current Trends and Advances in Agricultural Sciences Vol. 2" offers a captivating journey through the forefront of agricultural research and innovation. Through its diverse array of chapters, the volume provides a comprehensive exploration of emerging trends and advancements shaping the agricultural landscape. The chapter on Nano DAP introduces readers to the revolutionary potential of nanotechnology in fertilizer production. By harnessing the unique properties of nanoparticles, this chapter explores how Nano DAP enhances nutrient uptake efficiency, reduces environmental impacts, and improves crop yields, paving the way for sustainable agricultural practices. Contract farming emerges as a pivotal mechanism for agricultural development in another chapter. Readers are immersed in the intricacies of contractual agreements between farmers and agribusinesses, examining their role in improving market access, technology adoption, and income generation for smallholder farmers. Sericulture, the practice of silk production, takes pivotal position in this volume, offering insights into its historical significance, technological advancements, and economic implications. From silkworm rearing techniques to silk processing methods, this chapter provides a comprehensive overview of sericulture's contribution to rural livelihoods and global textile industries. Genome editing emerges as a transformative tool in agricultural biotechnology, unlocking new avenues for crop improvement and trait enhancement. Polyploidy, the phenomenon of possessing multiple sets of chromosomes, is examined in depth, shedding light on its role in crop domestication, evolution, and breeding. This chapter elucidates how polyploid crops exhibit enhanced genetic diversity and resilience, offering novel opportunities for crop improvement in the face of climate change. Beekeeping and biopesticides round out the volume, highlighting the crucial roles of pollinators and eco-friendly pest management strategies in

Published
2024

100. Proteomic analysis shows decreased Type I fibers and ectopic fat accumulation in skeletal muscle from women with PCOS

Author

Stener-Victorin, Elisabet, Eriksson, Gustaw, Shrestha, Man Mohan, Rodriguez Paris, Valentina, Lu, Haojiang, Banks, Jasmine, Samad, Manisha, Perian, Charlène, Jude, Baptiste, Engman, Viktor, Boi, Roberto, Nilsson, Emma, Ling, Charlotte, Nyström, Jenny, Wernstedt Asterholm, Ingrid, Turner, Nigel, Lanner, Johanna T., Benrick, Anna, Stener-Victorin, Elisabet, Eriksson, Gustaw, Shrestha, Man Mohan, Rodriguez Paris, Valentina, Lu, Haojiang, Banks, Jasmine, Samad, Manisha, Perian, Charlène, Jude, Baptiste, Engman, Viktor, Boi, Roberto, Nilsson, Emma, Ling, Charlotte, Nyström, Jenny, Wernstedt Asterholm, Ingrid, Turner, Nigel, Lanner, Johanna T., and Benrick, Anna

Abstract

Background: Polycystic ovary syndrome’s (PCOS) main feature is hyperandrogenism, which is linked to a higher risk of metabolic disorders in women. Gene expression analyses in adipose tissue and skeletal muscle reveal dysregulated metabolic pathways in women with PCOS, but these differences do not necessarily lead tochanges in protein levels and biological function. Methods: To advance our understanding of the molecular alterations in PCOS, we performed global proteomic and phosphorylation site analysis using tandem mass spectrometry. Adipose tissue and skeletal muscle were collected at baseline from 10 women with and without PCOS, and in women with PCOS after 5 weeks of treatment with electrical stimulation. Results: Perilipin-1, a protein that typically coats the surface of lipid droplets in adipocytes, was increased whereas proteins involved in muscle contraction and type I muscle fiber function were downregulated in PCOS muscle. Proteins in the thick and thin filaments had many altered phosphorylation sites, indicating differences in protein activity and function. The upregulated proteins in muscle post treatment were enriched in pathways involved in extracellular matrix organization and wound healing, which may reflect a protective adaptation to repeated contractions and tissue damage due to needling. A similar, albeit less pronounced, upregulation in extracellular matrix organization pathways was also seen in adipose tissue. Conclusions: Our results suggest that hyperandrogenic women with PCOS have higher levels of extramyocellular lipids and fewer oxidative insulin-sensitive type I muscle fibers. These could be key factors leading insulin resistance in PCOS muscle while electric stimulation-induced tissue remodeling may be protective., CC BY 4.0 DEED5 January 2024Corresponding author: Anna Benrick, University of Gothenburg, Institute of Neuroscience and Physiology, Department of Physiology, Box 432, 405 30 Gothenburg, Sweden. Phone: +46 (0)709490148. E-mail: anna.benrick@gu.seFunding: A.B. holds funding from the Swedish Research Council (2020-02485), E.SV. holds funding from the Swedish Research Council (2022-00550), the Novo Nordisk Foundation (NNF22OC0072904), and I.W.A. holds funding from the Swedish Research Council (2020-01463), Mary von Sydow Foundation, Diabetes Wellness Sverige, and EFSD//European Research Programme on ‘New Targets for Diabetes or Obesity-related Metabolic Diseases’ supported by MSD 2022, and J.N. holds funding from IngaBritt and Arne Lundberg Research Foundation.Manuskript i medRxiv: DOI: 10.1101/2023.03.08.23286896

Published
2024
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