Search

Your search keyword '"Mainprize, Todd"' showing total 89 results
Start Over Author "Mainprize, Todd"
89 results on '"Mainprize, Todd"'

54. 5th International Symposium on Focused Ultrasound

Author

Aerospace and Ocean Engineering, Abounader, Roger, Abraham, Christopher, Adema, Gosse, Agrawal, Punit, Airan, Raag, Aleman, Dionne, Alexander, Phillip, Alkins, Ryan, Alnazeer, Moez, Altman, Michael, Aly, Amirah, Amaral, Joao G., Amrahli, Maral, Amraoui, Sana, Andarawewa, Kumari, Andriyakhina, Yulia, Angstadt, Mary, Ankou, Bénédicte, Arias, Ana C., Arvanitis, Costas, Asadnia, Kiana, Aubert, Isabelle, Aubry, Jean-Francois, Aurup, Christian, Bader, Kenneth, Badr, Lena, Baek, Hongchae, Barbato, Gaetano, Beccaria, Kevin, Bellorofonte, Carlo, Benson, Lee, Bernus, Olivier, Berriet, Rémi, Bertolina, Jim, Beskin, Viktoriya, Bessière, Francis, Bethune, Allison, Bezzi, Mario, Bond, Aaron, Bonomo, Guido, Borowsky, Alexander, Borys, Nicolas, Böttcher, Joachim, Bouley, Donna, Bour, Pierre, Bourekas, Eric, Brenin, David, Brokman, Omer, Brosh, Inbar, Buckner, Andrew, Bullock, Timothy, Cafarelli, Andrea, Cahill, Jessica, Camarena, Francisco, Camelo-Piragua, Sandra, Campbell, Benjamin, Campbell, Fiona, Cannata, Jon, Canney, Michael, Carlson, Roy, Carneiro, Antonio, Carpentier, Alexandre, Catheline, Stefan, Cavin, Ian, Cesana, Claudio, Chabok, Hamid R., Chamanara, Marzieh, Chang, Jin H., Chang, Won S., Changizi, Barbara, Chapelon, Jean Y., Chaplin, Vandiver, Chapman, Martin, Chaudhary, Neeraj, Chaussy, Christian, Chen, Cherry, Chen, Johnny, Chen, Wohsing, Chen, Xiaoming, Chevalier, Philippe, Chiou, George, Chisholm, Alexander, Christofferson, Ivy, Chung, Hyun H., Ciuti, Gastone, Clement, Gregory, Cooper, Mark, Corea, Joseph, Corso, Cristiano, Cosman, Josh, Coughlin, Dezba, Crake, Calum, Cunitz, Bryan, Curiel, Laura, Curley, Colleen T., Czarnota, Gregory, Dababou, Susan, Dallapiazza, Robert, de Bever, Joshua, de Jager, Bram, de Ruiter, Joost, de Senneville, Baudouin D., Deckers, Roel, Delattre, Jean-Yves, den Brok, Martijn, Dhanaliwala, Ali, Diodato, Alessandro, Dixon, Adam, Donner, Elizabeth, Downs, Matthew, Du, Zhongmin, Dubois, Rémi, Dupre, Aurelien, Eikelenboom, Dylan, Elias, W. J., Ellens, Nicholas, Endre, Ruby, Eran, Ayelet, Erasmus, Hans-Peter, Everstine, Ashli, Farahani, Keyvan, Farrer, Alexis, Farry, Justin, Federau, Christian, Feng, Xue, Ferrer, Cyril, Ferrera, Vincent, Fishman, Paul, Foley, Jessica, Frenkel, Victor, Fütterer, Jurgen, Gach, H. M., Gandhi, Dheeraj, Gertner, Michael, Goldsher, Dorit, Gorgone, Alessandro, Greillier, Paul, Griesenauer, Rebekah, Grissom, William, Grondin, Julien, Guha, Chandan, Gulati, Amitabh, Gullapalli, Rao, Guo, Sijia, Gupta, Samit, Gurm, Hitinder, Gwinn, Ryder, Hadley, Rock, Haïssaguerre, Michel, Hammoud, Dima, Hananel, Arik, Hargrove, Amelia, Hatch, Robert, Haworth, Kevin, Hazan, Eilon, He, Ye, Heemels, Maurice, Heerschap, Arend, Hilas, Elaine, Hoang-Xuan, Khe, Hocini, Mélèze, Hodaie, Mojgan, Hofmann, Denis, Holland, Christy, Hoogenboom, Martijn, Hopyan, Sevan, Hossack, John, Houdouin, Alexandre, Hsu, Po-Hung, Hu, Jim, Hurwitz, Mark, Huss, Diane, Hwang, Chang-il, Hwang, Joo H., Idbaih, Ahmed, Ikeuchi, Masahiko, Ingham, Elizabeth, Ives, Kimberly, Izumi, Masashi, Jackson-Lewis, Vernice, Janát-Amsbury, Margit, Jang, Kee W., Jedruszczuk, Kathleen, Jiménez-Gambín, Sergio, Jiménez, Noé, Johnson, Sara, Jonathan, Sumeeth, Joy, Joyce, Jung, Hyun H., Jung, Na Y., Kahn, Itamar, Kamimura, Hermes, Kamrava, Seyed K., Kang, Jeeun, Kang, Kook J., Kang, Soo Y., Kao, Yi-tzu, Katti, Prateek, Kawasaki, Motohiro, Kaye, Elena, Keupp, Jochen, Kim, AeRang, Kim, Harry, Kim, Hyun-Chul, Kim, Hyuncheol, Kim, Hyungmin, Kim, Min S., Kim, Namho, Kiyasu, Katsuhito, Kneepkens, Esther, Knopp, Michael, Kobus, Thiele, Koral, Korgun, Kreider, Wayne, Krishna, Vibhor, Krug, Roland, Krupa, Steve, Kuo, Chia-Chun, Kwiecinski, Wojciech, Lacoste, Romain, Lam, Heather, Lamberti-Pasculli, Maria, Lang, Brian, Larner, James, Larrabee, Zachary, Leach, J. K., LeBlang, Suzanne, Leclercq, Delphine, Lee, Hak J., Lee, Jong-Hwan, Lehericy, Stéphane, Leighton, Wan, Leung, Steven, Lewis, Bobbi, Lewis, Matthew, Li, Dawei, Linn, Sabine, Lipsman, Nir, Liu, Hao-Li, Liu, Jingfei, Lopes, M. B., Lotz, Jeff, Lu, Xin, Lundt, Jonathan, Luo, Xi, Lustgarten, Lior, Lustig, Micheal, Macoskey, Jonathan, Madore, Bruno, Maev, Roman, Magat, Julie, Maimbourg, Guillaume, Maimon, Noam, Mainprize, Todd, Malayer, Jerry, Maples, Danny, Marquet, Fabrice, Marrocchio, Cristina, Marx, Mike, Mastorakos, Panagiotis, Mauri, Giovanni, McLean, Hailey, McMichael, John, Mead, Brian P., Melodelima, David, Melot-Dusseau, Sandrine, Menciassi, Arianna, Merrill, Robb, Meyer, Joshua, Midiri, Massimo, Miga, Michael, Migliore, Ilaria G., Miller, Eric, Minalga, Emilee, Moon, Hyungwon, Moore, David, Mourad, Pierre, Mouratidis, Petros, Mueller, Michael, Mugler, John, Muller, Sébastien, Namba, Hirofumi, Naor, Omer, Nassar, Maria, Nazai, Navid, Negron, Karina, Negussie, Ayele, Nguyen, Thai-Son, Nicolay, Klaas, Nikolaeva, Anastasia V., Oetgen, Matthew, Olive, Kenneth, Olumolade, Oluyemi, Orsi, Franco, Owens, Gabe, Ozilgen, Arda, Padegimas, Linas, Palermo, Carmine, Pan, Chia-Hsin, Pandey, Aditya, Papadakis, Georgios, Park, Chang K., Park, Sang M., Parker, Jonathon, Parvizi, Mohammad H., Pascal-Tenorio, Aurea, Patel, Janish, Patz, Sam, Payen, Thomas, Perich, Eloi, Pernot, Mathieu, Perol, David, Perry, James, Pillarisetty, Venu, Pioche, Mathieu, Pizzuto, Matthew, Plaksin, Michael, Plata, Juan, Price, Karl, Prince, Jessica, Przedborski, Serge, Quinones-Hinojosa, Alfredo, Ramachandran, Akhilesh, Ranjan, Ashish, Ravikumar, Vinod, Reichenbach, Juergen, Repasky, Elizabeth, Rezai, Ali, Ritter, Philippe, Rivoire, Michel, Rochman, Carrie, Rosenberg, Jarrett, Rosnitskiy, Pavel B., Ruiz, Antonio, Sahgal, Arjun, Samiotaki, Gesthimani, Sanghvi, Narendra, Santin, Mathieu D., Santos, Domiciano, Sasaki, Noboru, Sastra, Steve, Schade, George, Schall, Jeffrey, Schlesinger, Ilana, Schmitt, Paul, Schwaab, Julia, Scionti, Stephen, Scipione, Roberto, Scoarughi, Gian L., Scott, Serena, Sebeke, Lukas, Seifabadi, Reza, Seo, Jai, Sesenoglu-Laird, Ozge, Shah, Binit, Shahriari, Kian, Shaikh, Sumbul, Shea, Jill, Shi, Jiaqi, Shim, Jenny, Shinkov, Alexander, Shuman, Jillian, Silvestrini, Matthew, Sim, Changbeom, Sin, Vivian, Sinai, Alon, Singh, Manoj, Sinilshchikov, Ilya, Skalina, Karin, Slingluff, Craig, So, Po-Wah, Solomon, Stephen, Son, Keon H., Sperling, Scott, Stein, Ruben, Stein, Sherman, Stevens, Aaron, Stimec, Jennifer, Storm, Gert, Straube, William, Suelmann, Britt, Sutton, Jonathan, Svedin, Bryant, Takemasa, Ryuichi, Takiguchi, Mitsuyoshi, Tam, Emily, Tan, Jeremy, Tang, Xinyan, Tanter, Mickael, Tebebi, Pamela, Tehrani, Seruz, Temple, Michael, Teofilovic, Dejan, ter Haar, Gail, Terzi, Marina E., Thueroff, Stefan, Timbie, Kelsie, Tognarelli, Selene, Tretbar, Steffen, Trudeau, Maureen, Tsai, Yi-Chieh, Tsysar, Sergey A., Tucci, Samantha, Tuveson, David, Ushida, Takahiro, Vaessen, Paul, Vaillant, Fanny, Van Arsdell, Glen, van Breugel, Johanna, Van der Jeugd, Anneke, Van der Wall, Elsken, van Diest, Paul, van Stralen, Marijn, Varano, Gianluca, Velat, Manuela, Vidal-Jove, Joan, Vigna, Paolo D., Vignot, Alexandre, Vincenot, Jeremy, Vykhodtseva, Natalia, Wang, Bin, Wang, Han, Wang, Kevin, Wang, Qi, Wang, Qingguo, Wang, Shengping, Wang, Yak-Nam, Wang, Zhaorui, Wardlow, Rachel, Warren, Amy, Waszczak, Barbara, Watson, Katherine, Webb, Taylor, Wei-Bin, Shen, Wei, Kuo-Chen, Weiss, Steffen, Weissler, Yoni, Werner, Beat, Wesseling, Pieter, Williams, Noelle, Wilson, Emmanuel, Wintermark, Max, Witkamp, Arjen, Wong, Carlos, Wu, Jing-Fu, Wydra, Adrian, Xu, Alexis, Xu, Doudou, Xu, Su, Yang, Georgiana, Yang, Nai-Yi, Yao, Chen, Yarowsky, Paul, Ye, Patrick P., Yuldashev, Petr, Zaaroor, Menashe, Zachiu, Cornel, Zahos, Peter, Zangos, Stephan, Zhang, Dandan, Zhang, Hua, Zhang, Jimin, Zhang, Junhai, Zhang, Xi, Zhao, Li, Zhong, Pei, Zhuo, Jiachen, Zidowitz, Stephan, Zinke, Wolf, Zorgani, Ali, Aerospace and Ocean Engineering, Abounader, Roger, Abraham, Christopher, Adema, Gosse, Agrawal, Punit, Airan, Raag, Aleman, Dionne, Alexander, Phillip, Alkins, Ryan, Alnazeer, Moez, Altman, Michael, Aly, Amirah, Amaral, Joao G., Amrahli, Maral, Amraoui, Sana, Andarawewa, Kumari, Andriyakhina, Yulia, Angstadt, Mary, Ankou, Bénédicte, Arias, Ana C., Arvanitis, Costas, Asadnia, Kiana, Aubert, Isabelle, Aubry, Jean-Francois, Aurup, Christian, Bader, Kenneth, Badr, Lena, Baek, Hongchae, Barbato, Gaetano, Beccaria, Kevin, Bellorofonte, Carlo, Benson, Lee, Bernus, Olivier, Berriet, Rémi, Bertolina, Jim, Beskin, Viktoriya, Bessière, Francis, Bethune, Allison, Bezzi, Mario, Bond, Aaron, Bonomo, Guido, Borowsky, Alexander, Borys, Nicolas, Böttcher, Joachim, Bouley, Donna, Bour, Pierre, Bourekas, Eric, Brenin, David, Brokman, Omer, Brosh, Inbar, Buckner, Andrew, Bullock, Timothy, Cafarelli, Andrea, Cahill, Jessica, Camarena, Francisco, Camelo-Piragua, Sandra, Campbell, Benjamin, Campbell, Fiona, Cannata, Jon, Canney, Michael, Carlson, Roy, Carneiro, Antonio, Carpentier, Alexandre, Catheline, Stefan, Cavin, Ian, Cesana, Claudio, Chabok, Hamid R., Chamanara, Marzieh, Chang, Jin H., Chang, Won S., Changizi, Barbara, Chapelon, Jean Y., Chaplin, Vandiver, Chapman, Martin, Chaudhary, Neeraj, Chaussy, Christian, Chen, Cherry, Chen, Johnny, Chen, Wohsing, Chen, Xiaoming, Chevalier, Philippe, Chiou, George, Chisholm, Alexander, Christofferson, Ivy, Chung, Hyun H., Ciuti, Gastone, Clement, Gregory, Cooper, Mark, Corea, Joseph, Corso, Cristiano, Cosman, Josh, Coughlin, Dezba, Crake, Calum, Cunitz, Bryan, Curiel, Laura, Curley, Colleen T., Czarnota, Gregory, Dababou, Susan, Dallapiazza, Robert, de Bever, Joshua, de Jager, Bram, de Ruiter, Joost, de Senneville, Baudouin D., Deckers, Roel, Delattre, Jean-Yves, den Brok, Martijn, Dhanaliwala, Ali, Diodato, Alessandro, Dixon, Adam, Donner, Elizabeth, Downs, Matthew, Du, Zhongmin, Dubois, Rémi, Dupre, Aurelien, Eikelenboom, Dylan, Elias, W. J., Ellens, Nicholas, Endre, Ruby, Eran, Ayelet, Erasmus, Hans-Peter, Everstine, Ashli, Farahani, Keyvan, Farrer, Alexis, Farry, Justin, Federau, Christian, Feng, Xue, Ferrer, Cyril, Ferrera, Vincent, Fishman, Paul, Foley, Jessica, Frenkel, Victor, Fütterer, Jurgen, Gach, H. M., Gandhi, Dheeraj, Gertner, Michael, Goldsher, Dorit, Gorgone, Alessandro, Greillier, Paul, Griesenauer, Rebekah, Grissom, William, Grondin, Julien, Guha, Chandan, Gulati, Amitabh, Gullapalli, Rao, Guo, Sijia, Gupta, Samit, Gurm, Hitinder, Gwinn, Ryder, Hadley, Rock, Haïssaguerre, Michel, Hammoud, Dima, Hananel, Arik, Hargrove, Amelia, Hatch, Robert, Haworth, Kevin, Hazan, Eilon, He, Ye, Heemels, Maurice, Heerschap, Arend, Hilas, Elaine, Hoang-Xuan, Khe, Hocini, Mélèze, Hodaie, Mojgan, Hofmann, Denis, Holland, Christy, Hoogenboom, Martijn, Hopyan, Sevan, Hossack, John, Houdouin, Alexandre, Hsu, Po-Hung, Hu, Jim, Hurwitz, Mark, Huss, Diane, Hwang, Chang-il, Hwang, Joo H., Idbaih, Ahmed, Ikeuchi, Masahiko, Ingham, Elizabeth, Ives, Kimberly, Izumi, Masashi, Jackson-Lewis, Vernice, Janát-Amsbury, Margit, Jang, Kee W., Jedruszczuk, Kathleen, Jiménez-Gambín, Sergio, Jiménez, Noé, Johnson, Sara, Jonathan, Sumeeth, Joy, Joyce, Jung, Hyun H., Jung, Na Y., Kahn, Itamar, Kamimura, Hermes, Kamrava, Seyed K., Kang, Jeeun, Kang, Kook J., Kang, Soo Y., Kao, Yi-tzu, Katti, Prateek, Kawasaki, Motohiro, Kaye, Elena, Keupp, Jochen, Kim, AeRang, Kim, Harry, Kim, Hyun-Chul, Kim, Hyuncheol, Kim, Hyungmin, Kim, Min S., Kim, Namho, Kiyasu, Katsuhito, Kneepkens, Esther, Knopp, Michael, Kobus, Thiele, Koral, Korgun, Kreider, Wayne, Krishna, Vibhor, Krug, Roland, Krupa, Steve, Kuo, Chia-Chun, Kwiecinski, Wojciech, Lacoste, Romain, Lam, Heather, Lamberti-Pasculli, Maria, Lang, Brian, Larner, James, Larrabee, Zachary, Leach, J. K., LeBlang, Suzanne, Leclercq, Delphine, Lee, Hak J., Lee, Jong-Hwan, Lehericy, Stéphane, Leighton, Wan, Leung, Steven, Lewis, Bobbi, Lewis, Matthew, Li, Dawei, Linn, Sabine, Lipsman, Nir, Liu, Hao-Li, Liu, Jingfei, Lopes, M. B., Lotz, Jeff, Lu, Xin, Lundt, Jonathan, Luo, Xi, Lustgarten, Lior, Lustig, Micheal, Macoskey, Jonathan, Madore, Bruno, Maev, Roman, Magat, Julie, Maimbourg, Guillaume, Maimon, Noam, Mainprize, Todd, Malayer, Jerry, Maples, Danny, Marquet, Fabrice, Marrocchio, Cristina, Marx, Mike, Mastorakos, Panagiotis, Mauri, Giovanni, McLean, Hailey, McMichael, John, Mead, Brian P., Melodelima, David, Melot-Dusseau, Sandrine, Menciassi, Arianna, Merrill, Robb, Meyer, Joshua, Midiri, Massimo, Miga, Michael, Migliore, Ilaria G., Miller, Eric, Minalga, Emilee, Moon, Hyungwon, Moore, David, Mourad, Pierre, Mouratidis, Petros, Mueller, Michael, Mugler, John, Muller, Sébastien, Namba, Hirofumi, Naor, Omer, Nassar, Maria, Nazai, Navid, Negron, Karina, Negussie, Ayele, Nguyen, Thai-Son, Nicolay, Klaas, Nikolaeva, Anastasia V., Oetgen, Matthew, Olive, Kenneth, Olumolade, Oluyemi, Orsi, Franco, Owens, Gabe, Ozilgen, Arda, Padegimas, Linas, Palermo, Carmine, Pan, Chia-Hsin, Pandey, Aditya, Papadakis, Georgios, Park, Chang K., Park, Sang M., Parker, Jonathon, Parvizi, Mohammad H., Pascal-Tenorio, Aurea, Patel, Janish, Patz, Sam, Payen, Thomas, Perich, Eloi, Pernot, Mathieu, Perol, David, Perry, James, Pillarisetty, Venu, Pioche, Mathieu, Pizzuto, Matthew, Plaksin, Michael, Plata, Juan, Price, Karl, Prince, Jessica, Przedborski, Serge, Quinones-Hinojosa, Alfredo, Ramachandran, Akhilesh, Ranjan, Ashish, Ravikumar, Vinod, Reichenbach, Juergen, Repasky, Elizabeth, Rezai, Ali, Ritter, Philippe, Rivoire, Michel, Rochman, Carrie, Rosenberg, Jarrett, Rosnitskiy, Pavel B., Ruiz, Antonio, Sahgal, Arjun, Samiotaki, Gesthimani, Sanghvi, Narendra, Santin, Mathieu D., Santos, Domiciano, Sasaki, Noboru, Sastra, Steve, Schade, George, Schall, Jeffrey, Schlesinger, Ilana, Schmitt, Paul, Schwaab, Julia, Scionti, Stephen, Scipione, Roberto, Scoarughi, Gian L., Scott, Serena, Sebeke, Lukas, Seifabadi, Reza, Seo, Jai, Sesenoglu-Laird, Ozge, Shah, Binit, Shahriari, Kian, Shaikh, Sumbul, Shea, Jill, Shi, Jiaqi, Shim, Jenny, Shinkov, Alexander, Shuman, Jillian, Silvestrini, Matthew, Sim, Changbeom, Sin, Vivian, Sinai, Alon, Singh, Manoj, Sinilshchikov, Ilya, Skalina, Karin, Slingluff, Craig, So, Po-Wah, Solomon, Stephen, Son, Keon H., Sperling, Scott, Stein, Ruben, Stein, Sherman, Stevens, Aaron, Stimec, Jennifer, Storm, Gert, Straube, William, Suelmann, Britt, Sutton, Jonathan, Svedin, Bryant, Takemasa, Ryuichi, Takiguchi, Mitsuyoshi, Tam, Emily, Tan, Jeremy, Tang, Xinyan, Tanter, Mickael, Tebebi, Pamela, Tehrani, Seruz, Temple, Michael, Teofilovic, Dejan, ter Haar, Gail, Terzi, Marina E., Thueroff, Stefan, Timbie, Kelsie, Tognarelli, Selene, Tretbar, Steffen, Trudeau, Maureen, Tsai, Yi-Chieh, Tsysar, Sergey A., Tucci, Samantha, Tuveson, David, Ushida, Takahiro, Vaessen, Paul, Vaillant, Fanny, Van Arsdell, Glen, van Breugel, Johanna, Van der Jeugd, Anneke, Van der Wall, Elsken, van Diest, Paul, van Stralen, Marijn, Varano, Gianluca, Velat, Manuela, Vidal-Jove, Joan, Vigna, Paolo D., Vignot, Alexandre, Vincenot, Jeremy, Vykhodtseva, Natalia, Wang, Bin, Wang, Han, Wang, Kevin, Wang, Qi, Wang, Qingguo, Wang, Shengping, Wang, Yak-Nam, Wang, Zhaorui, Wardlow, Rachel, Warren, Amy, Waszczak, Barbara, Watson, Katherine, Webb, Taylor, Wei-Bin, Shen, Wei, Kuo-Chen, Weiss, Steffen, Weissler, Yoni, Werner, Beat, Wesseling, Pieter, Williams, Noelle, Wilson, Emmanuel, Wintermark, Max, Witkamp, Arjen, Wong, Carlos, Wu, Jing-Fu, Wydra, Adrian, Xu, Alexis, Xu, Doudou, Xu, Su, Yang, Georgiana, Yang, Nai-Yi, Yao, Chen, Yarowsky, Paul, Ye, Patrick P., Yuldashev, Petr, Zaaroor, Menashe, Zachiu, Cornel, Zahos, Peter, Zangos, Stephan, Zhang, Dandan, Zhang, Hua, Zhang, Jimin, Zhang, Junhai, Zhang, Xi, Zhao, Li, Zhong, Pei, Zhuo, Jiachen, Zidowitz, Stephan, Zinke, Wolf, and Zorgani, Ali

Published
2016

56. 5th International Symposium on Focused Ultrasound

Author

Zaaroor, Menashe, primary, Sinai, Alon, additional, Goldsher, Dorit, additional, Eran, Ayelet, additional, Nassar, Maria, additional, Schlesinger, Ilana, additional, Parker, Jonathon, additional, Ravikumar, Vinod, additional, Ghanouni, Pejman, additional, Stein, Sherman, additional, Halpern, Casey, additional, Krishna, Vibhor, additional, Hargrove, Amelia, additional, Agrawal, Punit, additional, Changizi, Barbara, additional, Bourekas, Eric, additional, Knopp, Michael, additional, Rezai, Ali, additional, Mead, Brian, additional, Kim, Namho, additional, Mastorakos, Panagiotis, additional, Suk, Jung Soo, additional, Miller, Wilson, additional, Klibanov, Alexander, additional, Hanes, Justin, additional, Price, Richard, additional, Wang, Shutao, additional, Olumolade, Oluyemi, additional, Kugelman, Tara, additional, Jackson-Lewis, Vernice, additional, Karakatsani, Maria Eleni, additional, Han, Yang, additional, Przedborski, Serge, additional, Konofagou, Elisa, additional, Hynynen, Kullervo, additional, Aubert, Isabelle, additional, Leinenga, Gerhard, additional, Nisbet, Rebecca, additional, Hatch, Robert, additional, Van der Jeugd, Anneke, additional, Evans, Harrison, additional, Götz, Jürgen, additional, Van der Jeugd, Ann, additional, Fishman, Paul, additional, Yarowsky, Paul, additional, Frenkel, Victor, additional, Wei-Bin, Shen, additional, Nguyen, Ben, additional, Sanchez, Carlos Sierra, additional, Acosta, Camilo, additional, Chen, Cherry, additional, Wu, Shih-Ying, additional, Aryal, Muna, additional, Papademetriou, Iason T., additional, Zhang, Yong-Zhi, additional, Power, Chanikarn, additional, McDannold, Nathan, additional, Porter, Tyrone, additional, Kovacs, Zsofia, additional, Kim, Saejeong, additional, Jikaria, Neekita, additional, Qureshi, Farhan, additional, Bresler, Michele, additional, Frank, Joseph, additional, Odéen, Henrik, additional, Chiou, George, additional, Snell, John, additional, Todd, Nick, additional, Madore, Bruno, additional, Parker, Dennis, additional, Pauly, Kim Butts, additional, Marx, Mike, additional, Jonathan, Sumeeth, additional, Grissom, William, additional, Arvanitis, Costas, additional, Clement, Gregory, additional, de Bever, Joshua, additional, Payne, Allison, additional, Christensen, Douglas, additional, Maimbourg, Guillaume, additional, Santin, Mathieu David, additional, Houdouin, Alexandre, additional, Lehericy, Stéphane, additional, Tanter, Mickael, additional, Aubry, Jean Francois, additional, Federau, Christian, additional, Werner, Beat, additional, Paeng, Dong-Guk, additional, Xu, Zhiyuan, additional, Quigg, Anders, additional, Eames, Matt, additional, Jin, Changzhu, additional, Everstine, Ashli, additional, Sheehan, Jason, additional, Lopes, M. Beatriz, additional, Kassell, Neal, additional, Drake, James, additional, Price, Karl, additional, Lustgarten, Lior, additional, Sin, Vivian, additional, Mougenot, Charles, additional, Donner, Elizabeth, additional, Tam, Emily, additional, Hodaie, Mojgan, additional, Waspe, Adam, additional, Looi, Thomas, additional, Pichardo, Samuel, additional, Lee, Wonhye, additional, Chung, Yong An, additional, Jung, Yujin, additional, Song, In-Uk, additional, Yoo, Seung-Schik, additional, Kim, Hyun-Chul, additional, Lee, Jong-Hwan, additional, Caskey, Charles, additional, Zinke, Wolf, additional, Cosman, Josh, additional, Shuman, Jillian, additional, Schall, Jeffrey, additional, Aurup, Christian, additional, Chen, Hong, additional, Kamimura, Hermes, additional, Carneiro, Antonio, additional, Sun, Tao, additional, Nazai, Navid, additional, Patz, Sam, additional, Livingstone, Margaret, additional, Mainprize, Todd, additional, Huang, Yuexi, additional, Alkins, Ryan, additional, Chapman, Martin, additional, Perry, James, additional, Lipsman, Nir, additional, Bethune, Allison, additional, Sahgal, Arjun, additional, Trudeau, Maureen, additional, Liu, Hao-Li, additional, Hsu, Po-Hung, additional, Wei, Kuo-Chen, additional, Sutton, Jonathan, additional, Alexander, Phillip, additional, Miller, Eric, additional, Kobus, Thiele, additional, Carpentier, Alexandre, additional, Canney, Michael, additional, Vignot, Alexandre, additional, Beccaria, Kevin, additional, Leclercq, Delphine, additional, Lafon, Cyril, additional, Chapelon, Jean Yves, additional, Hoang-Xuan, Khe, additional, Delattre, Jean-Yves, additional, Idbaih, Ahmed, additional, Moore, David, additional, Xu, Alexis, additional, Schmitt, Paul, additional, Foley, Jessica, additional, Sukovich, Jonathan, additional, Cain, Charles, additional, Pandey, Aditya, additional, Chaudhary, Neeraj, additional, Camelo-Piragua, Sandra, additional, Allen, Steven, additional, Cannata, Jon, additional, Teofilovic, Dejan, additional, Bertolina, Jim, additional, Hall, Timothy, additional, Xu, Zhen, additional, Grondin, Julien, additional, Ferrera, Vincent, additional, ter Haar, Gail, additional, Mouratidis, Petros, additional, Repasky, Elizabeth, additional, Timbie, Kelsie, additional, Badr, Lena, additional, Campbell, Benjamin, additional, McMichael, John, additional, Buckner, Andrew, additional, Prince, Jessica, additional, Stevens, Aaron, additional, Bullock, Timothy, additional, Skalina, Karin, additional, Guha, Chandan, additional, Orsi, Franco, additional, Bonomo, Guido, additional, Vigna, Paolo Della, additional, Mauri, Giovanni, additional, Varano, Gianluca, additional, Schade, George, additional, Wang, Yak-Nam, additional, Pillarisetty, Venu, additional, Hwang, Joo Ha, additional, Khokhlova, Vera, additional, Bailey, Michael, additional, Khokhlova, Tatiana, additional, Sinilshchikov, Ilya, additional, Yuldashev, Petr, additional, Andriyakhina, Yulia, additional, Kreider, Wayne, additional, Maxwell, Adam, additional, Sapozhnikov, Oleg, additional, Partanen, Ari, additional, Lundt, Jonathan, additional, Preusser, Tobias, additional, Haase, Sabrina, additional, Bezzi, Mario, additional, Jenne, Jürgen, additional, Langø, Thomas, additional, Midiri, Massimo, additional, Mueller, Michael, additional, Sat, Giora, additional, Tanner, Christine, additional, Zangos, Stephan, additional, Guenther, Matthias, additional, Melzer, Andreas, additional, Menciassi, Arianna, additional, Tognarelli, Selene, additional, Cafarelli, Andrea, additional, Diodato, Alessandro, additional, Ciuti, Gastone, additional, Rothluebbers, Sven, additional, Schwaab, Julia, additional, Strehlow, Jan, additional, Mihcin, Senay, additional, Tretbar, Steffen, additional, Payen, Thomas, additional, Palermo, Carmine, additional, Sastra, Steve, additional, Olive, Kenneth, additional, Adams, Matthew, additional, Salgaonkar, Vasant, additional, Scott, Serena, additional, Sommer, Graham, additional, Diederich, Chris, additional, Vidal-Jove, Joan, additional, Perich, Eloi, additional, Ruiz, Antonio, additional, Velat, Manuela, additional, Melodelima, David, additional, Dupre, Aurelien, additional, Vincenot, Jeremy, additional, Yao, Chen, additional, Perol, David, additional, Rivoire, Michel, additional, Tucci, Samantha, additional, Mahakian, Lisa, additional, Fite, Brett, additional, Ingham, Elizabeth, additional, Tam, Sarah, additional, Hwang, Chang-il, additional, Tuveson, David, additional, Ferrara, Katherine, additional, Scionti, Stephen, additional, Chen, Lili, additional, Cvetkovic, Dusica, additional, Chen, Xiaoming, additional, Gupta, Roohi, additional, Wang, Bin, additional, Ma, Charlie, additional, Bader, Kenneth, additional, Haworth, Kevin, additional, Holland, Christy, additional, Sanghvi, Narendra, additional, Carlson, Roy, additional, Chen, Wohsing, additional, Chaussy, Christian, additional, Thueroff, Stefan, additional, Cesana, Claudio, additional, Bellorofonte, Carlo, additional, Wang, Qingguo, additional, Wang, Han, additional, Wang, Shengping, additional, Zhang, Junhai, additional, Bazzocchi, Alberto, additional, Napoli, Alessandro, additional, Staruch, Robert, additional, Bing, Chenchen, additional, Shaikh, Sumbul, additional, Nofiele, Joris, additional, Szczepanski, Debra, additional, Staruch, Michelle Wodzak, additional, Williams, Noelle, additional, Laetsch, Theodore, additional, Chopra, Rajiv, additional, Rosenberg, Jarrett, additional, Bitton, Rachelle, additional, LeBlang, Suzanne, additional, Meyer, Joshua, additional, Hurwitz, Mark, additional, Yarmolenko, Pavel, additional, Celik, Haydar, additional, Eranki, Avinash, additional, Beskin, Viktoriya, additional, Santos, Domiciano, additional, Patel, Janish, additional, Oetgen, Matthew, additional, Kim, AeRang, additional, Kim, Peter, additional, Sharma, Karun, additional, Chisholm, Alexander, additional, Aleman, Dionne, additional, Scipione, Roberto, additional, Temple, Michael, additional, Amaral, Joao Guilherme, additional, Endre, Ruby, additional, Lamberti-Pasculli, Maria, additional, de Ruiter, Joost, additional, Campbell, Fiona, additional, Stimec, Jennifer, additional, Gupta, Samit, additional, Singh, Manoj, additional, Hopyan, Sevan, additional, Czarnota, Gregory, additional, Brenin, David, additional, Rochman, Carrie, additional, Kovatcheva, Roussanka, additional, Vlahov, Jordan, additional, Zaletel, Katja, additional, Stoinov, Julian, additional, Bucknor, Matthew, additional, Rieke, Viola, additional, Shim, Jenny, additional, Koral, Korgun, additional, Lang, Brian, additional, Wong, Carlos, additional, Lam, Heather, additional, Shinkov, Alexander, additional, Hu, Jim, additional, Zhang, Xi, additional, Macoskey, Jonathan, additional, Ives, Kimberly, additional, Owens, Gabe, additional, Gurm, Hitinder, additional, Shi, Jiaqi, additional, Pizzuto, Matthew, additional, Dillon, Christopher, additional, Christofferson, Ivy, additional, Hilas, Elaine, additional, Shea, Jill, additional, Greillier, Paul, additional, Ankou, Bénédicte, additional, Bessière, Francis, additional, Zorgani, Ali, additional, Pioche, Mathieu, additional, Kwiecinski, Wojciech, additional, Magat, Julie, additional, Melot-Dusseau, Sandrine, additional, Lacoste, Romain, additional, Quesson, Bruno, additional, Pernot, Mathieu, additional, Catheline, Stefan, additional, Chevalier, Philippe, additional, Marquet, Fabrice, additional, Bour, Pierre, additional, Vaillant, Fanny, additional, Amraoui, Sana, additional, Dubois, Rémi, additional, Ritter, Philippe, additional, Haïssaguerre, Michel, additional, Hocini, Mélèze, additional, Bernus, Olivier, additional, Tebebi, Pamela, additional, Burks, Scott, additional, Milo, Blerta, additional, Gertner, Michael, additional, Zhang, Jimin, additional, Wong, Andrew, additional, Liu, Yu, additional, Kheirolomoom, Azadeh, additional, Seo, Jai, additional, Watson, Katherine, additional, Zhang, Hua, additional, Foiret, Josquin, additional, Borowsky, Alexander, additional, Xu, Doudou, additional, Thanou, Maya, additional, Centelles, Miguell, additional, Wright, Mike, additional, Amrahli, Maral, additional, So, Po-Wah, additional, Gedroyc, Wladyslaw, additional, Kneepkens, Esther, additional, Heijman, Edwin, additional, Keupp, Jochen, additional, Weiss, Steffen, additional, Nicolay, Klaas, additional, Grüll, Holger, additional, Nagle, Matthew, additional, Nikolaeva, Anastasia V., additional, Terzi, Marina E., additional, Tsysar, Sergey A., additional, Cunitz, Bryan, additional, Mourad, Pierre, additional, Downs, Matthew, additional, Yang, Georgiana, additional, Wang, Qi, additional, Chen, Johnny, additional, Farry, Justin, additional, Dixon, Adam, additional, Du, Zhongmin, additional, Dhanaliwala, Ali, additional, Hossack, John, additional, Ranjan, Ashish, additional, Maples, Danny, additional, Wardlow, Rachel, additional, Malayer, Jerry, additional, Ramachandran, Akhilesh, additional, Namba, Hirofumi, additional, Kawasaki, Motohiro, additional, Izumi, Masashi, additional, Kiyasu, Katsuhito, additional, Takemasa, Ryuichi, additional, Ikeuchi, Masahiko, additional, Ushida, Takahiro, additional, Crake, Calum, additional, Kothapalli, Satya V. V. N., additional, Leighton, Wan, additional, Wang, Zhaorui, additional, Gach, H. Michael, additional, Straube, William, additional, Altman, Michael, additional, Kim, Young-sun, additional, Lim, Hyo Keun, additional, Rhim, Hyunchul, additional, van Breugel, Johanna, additional, Braat, Manon, additional, Moonen, Chrit, additional, van den Bosch, Maurice, additional, Ries, Mario, additional, Marrocchio, Cristina, additional, Dababou, Susan, additional, Lee, Jae Young, additional, Chung, Hyun Hoon, additional, Kang, Soo Yeon, additional, Kang, Kook Jin, additional, Son, Keon Ho, additional, Zhang, Dandan, additional, Plata, Juan, additional, Jones, Peter, additional, Pascal-Tenorio, Aurea, additional, Bouley, Donna, additional, Bond, Aaron, additional, Dallapiazza, Robert, additional, Huss, Diane, additional, Warren, Amy, additional, Sperling, Scott, additional, Gwinn, Ryder, additional, Shah, Binit, additional, Elias, W. Jeff, additional, Curley, Colleen, additional, Zhang, Ying, additional, Negron, Karina, additional, Abounader, Roger, additional, Samiotaki, Gesthimani, additional, Tu, Tsang-Wei, additional, Papadakis, Georgios, additional, Hammoud, Dima, additional, Silvestrini, Matthew, additional, Wolfram, Frank, additional, Güllmar, Daniel, additional, Reichenbach, Juergen, additional, Hofmann, Denis, additional, Böttcher, Joachim, additional, Schubert, Harald, additional, Lesser, Thomas G., additional, Almquist, Scott, additional, Camarena, Francisco, additional, Jiménez-Gambín, Sergio, additional, Jiménez, Noé, additional, Chang, Jin Woo, additional, Chaplin, Vandiver, additional, Griesenauer, Rebekah, additional, Miga, Michael, additional, Ellens, Nicholas, additional, Airan, Raag, additional, Quinones-Hinojosa, Alfredo, additional, Farahani, Keyvan, additional, Feng, Xue, additional, Fielden, Samuel, additional, Zhao, Li, additional, Wintermark, Max, additional, Meyer, Craig, additional, Guo, Sijia, additional, Lu, Xin, additional, Zhuo, Jiachen, additional, Xu, Su, additional, Gullapalli, Rao, additional, Gandhi, Dheeraj, additional, Brokman, Omer, additional, Baek, Hongchae, additional, Kim, Hyungmin, additional, Leung, Steven, additional, Webb, Taylor, additional, Vykhodtseva, Natalia, additional, Nguyen, Thai-Son, additional, Park, Chang Kyu, additional, Park, Sang Man, additional, Jung, Na Young, additional, Kim, Min Soo, additional, Chang, Won Seok, additional, Jung, Hyun Ho, additional, Plaksin, Michael, additional, Weissler, Yoni, additional, Shoham, Shy, additional, Kimmel, Eitan, additional, Rosnitskiy, Pavel B., additional, Krupa, Steve, additional, Hazan, Eilon, additional, Naor, Omer, additional, Levy, Yoav, additional, Maimon, Noam, additional, Brosh, Inbar, additional, Kahn, Itamar, additional, Cahill, Jessica, additional, Colas, Elodie Constanciel, additional, Wydra, Adrian, additional, Maev, Roman, additional, Aly, Amirah, additional, Sesenoglu-Laird, Ozge, additional, Padegimas, Linas, additional, Cooper, Mark, additional, Waszczak, Barbara, additional, Tehrani, Seruz, additional, Slingluff, Craig, additional, Larner, James, additional, Andarawewa, Kumari, additional, Ozhinsky, Eugene, additional, Shah, Rutwik, additional, Krug, Roland, additional, Deckers, Roel, additional, Linn, Sabine, additional, Suelmann, Britt, additional, Witkamp, Arjen, additional, Vaessen, Paul, additional, van Diest, Paul, additional, Bartels, Lambertus W., additional, Bos, Clemens, additional, Borys, Nicolas, additional, Storm, Gert, additional, Van der Wall, Elsken, additional, Farr, Navid, additional, Alnazeer, Moez, additional, Katti, Prateek, additional, Wood, Bradford, additional, Farrer, Alexis, additional, Ferrer, Cyril, additional, de Senneville, Baudouin Denis, additional, van Stralen, Marijn, additional, Liu, Jingfei, additional, Leach, J. Kent, additional, Zidowitz, Stephan, additional, Lee, Hsin-Lun, additional, Hsu, Fang-Chi, additional, Kuo, Chia-Chun, additional, Jeng, Shiu-Chen, additional, Chen, Tung-Ho, additional, Yang, Nai-Yi, additional, Chiou, Jeng-Fong, additional, Kao, Yi-tzu, additional, Pan, Chia-Hsin, additional, Wu, Jing-Fu, additional, Tsai, Yi-Chieh, additional, Johnson, Sara, additional, Li, Dawei, additional, He, Ye, additional, Karakitsios, Ioannis, additional, Schwenke, Michael, additional, Demedts, Daniel, additional, Xiao, Xu, additional, Cavin, Ian, additional, Minalga, Emilee, additional, Merrill, Robb, additional, Hadley, Rock, additional, Ramaekers, Pascal, additional, de Greef, Martijn, additional, Shahriari, Kian, additional, Parvizi, Mohammad Hossein, additional, Asadnia, Kiana, additional, Chamanara, Marzieh, additional, Kamrava, Seyed Kamran, additional, Chabok, Hamid Reza, additional, Stein, Ruben, additional, Muller, Sébastien, additional, Tan, Jeremy, additional, Zachiu, Cornel, additional, Erasmus, Hans-Peter, additional, Van Arsdell, Glen, additional, Benson, Lee, additional, Jang, Kee W., additional, Angstadt, Mary, additional, Lewis, Bobbi, additional, McLean, Hailey, additional, Hoogenboom, Martijn, additional, Eikelenboom, Dylan, additional, den Brok, Martijn, additional, Wesseling, Pieter, additional, Heerschap, Arend, additional, Fütterer, Jurgen, additional, Adema, Gosse, additional, Wang, Kevin, additional, Zhong, Pei, additional, Joy, Joyce, additional, McLeod, Helen, additional, Kim, Harry, additional, Lewis, Matthew, additional, Ozilgen, Arda, additional, Zahos, Peter, additional, Coughlin, Dezba, additional, Tang, Xinyan, additional, Lotz, Jeff, additional, Jedruszczuk, Kathleen, additional, Gulati, Amitabh, additional, Solomon, Stephen, additional, Kaye, Elena, additional, Mugler, John, additional, Barbato, Gaetano, additional, Scoarughi, Gian Luca, additional, Corso, Cristiano, additional, Gorgone, Alessandro, additional, Migliore, Ilaria Giuseppina, additional, Larrabee, Zachary, additional, Hananel, Arik, additional, Aubry, Jean-Francois, additional, Negussie, Ayele, additional, Wilson, Emmanuel, additional, Seifabadi, Reza, additional, Moon, Hyungwon, additional, Kang, Jeeun, additional, Sim, Changbeom, additional, Chang, Jin Ho, additional, Kim, Hyuncheol, additional, Lee, Hak Jong, additional, Sasaki, Noboru, additional, Takiguchi, Mitsuyoshi, additional, Sebeke, Lukas, additional, Luo, Xi, additional, de Jager, Bram, additional, Heemels, Maurice, additional, Abraham, Christopher, additional, Curiel, Laura, additional, Berriet, Rémi, additional, Janát-Amsbury, Margit, additional, Corea, Joseph, additional, Ye, Patrick Peiyong, additional, Arias, Ana Clauda, additional, Lustig, Micheal, additional, and Svedin, Bryant, additional

Published
2016
Full Text
View/download PDF

58. Stereotactic radiosurgery for resected brain metastasis: Cavity dynamics and factors affecting its evolution.

Author

Alghamdi, Majed, Hasan, Yaser, Ruschin, Mark, Atenafu, Eshetu G., Myrehaug, Sten, Chia-Lin Tseng, Spears, Julian, Mainprize, Todd, Sahgal, Arjun, and Soliman, Hany

Subjects
STEREOTACTIC radiosurgery, BRAIN metastasis, POSTOPERATIVE care, MULTIVARIATE analysis, UNIVARIATE analysis
Abstract

Objective: To determine changes in post-surgical cavity volume for metastases based on time from surgery, pre-operative tumor dimensions and other predictors, in patients planned for postoperative stereotactic radiosurgery (SRS). Methods: Patients with resected brain metastases from a primary solid tumor, treated with postoperative surgical cavity SRS from 2008 to 2014 were identified from an institutional prospective database. The segmented three-dimensional (3D) volume of the pre-operative tumor and postoperative surgical cavity were determined based on MRI and percent volume change was calculated. Patients were grouped according to early (<21 days), intermediate (22-42 days), and late (>42 days) intervals based on the number of days between the date of surgery and the treatment planning MRI. Potential predictive factors including tumor size, location, age, dural involvement, and degree of surgical resection were also analyzed. Results: Sixty-one cavities in 59 patients were evaluated. Overall, a significant volume reduction (4cm3, p=0.03) was observed comparing tumor and cavity volumes. For larger tumors, an average volume reduction of 11.6% (p=0.01) was observed compared to an increase of 34.4% in smaller tumors (p=0.69). For both large and small tumors, cavities were larger in the early interval especially for smaller tumors. During the intermediate interval, a significant volume reduction was observed for larger tumors (28%, p=0.0007). Tumor size, dural involvement, age and time from surgery were significant predictors for volume change on univariate analysis. On multivariate analysis, tumor size, dural involvement and time from surgery were significant. Conclusion: Tumor size (>3cm), dural involvement and longer time from surgery were significant predictors of cavity volume reduction. Caution must be taken when treating cavities in the early (<21 days) interval after surgery as it may lead to irradiating more normal tissue especially in small tumors. [ABSTRACT FROM AUTHOR]

Published
2018

64. A Systematic Review of the Effects of Resident Duty Hour Restrictions in Surgery

Author

Ahmed, Najma, primary, Devitt, Katharine S., additional, Keshet, Itay, additional, Spicer, Jonathan, additional, Imrie, Kevin, additional, Feldman, Liane, additional, Cools-Lartigue, Jonathan, additional, Kayssi, Ahmed, additional, Lipsman, Nir, additional, Elmi, Maryam, additional, Kulkarni, Abhaya V., additional, Parshuram, Chris, additional, Mainprize, Todd, additional, Warren, Richard J., additional, Fata, Paola, additional, Gorman, M. Sean, additional, Feinberg, Stan, additional, and Rutka, James, additional

Published
2014
Full Text
View/download PDF

65. Tracheostomy timing in traumatic brain injury

Author

Alali, Aziz S., primary, Scales, Damon C., additional, Fowler, Robert A., additional, Mainprize, Todd G., additional, Ray, Joel G., additional, Kiss, Alexander, additional, de Mestral, Charles, additional, and Nathens, Avery B., additional

Published
2014
Full Text
View/download PDF

66. Hypofractionated Stereotactic Radiotherapy in Five Daily Fractions for Post-Operative Surgical Cavities in Brain Metastases Patients with and without Prior Whole Brain Radiation

Author

Al-Omair, Ameen, primary, Soliman, Hany, additional, Xu, Wei, additional, Karotki, Aliaksandr, additional, Mainprize, Todd, additional, Phan, Nicolas, additional, Das, Sunit, additional, Keith, Julia, additional, Yeung, Robert, additional, Perry, James, additional, Tsao, May, additional, and Sahgal, Arjun, additional

Published
2013
Full Text
View/download PDF

67. Multifocal Cerebellar Liponeurocytoma

Author

Pelz, David, primary, Khezri, Navid, additional, Mainprize, Todd, additional, Phan, Nicolas, additional, Keith, Julia, additional, Bilbao, Juan, additional, Aviv, Richard I., additional, Tsao, May, additional, and Symons, Sean P., additional

Published
2013
Full Text
View/download PDF

75. Pathology Case Study: Intraventricular Mass

Author

Bilbao, Juan M., 1938, Mainprize, Todd, Bilbao, Juan M., 1938, and Mainprize, Todd

Abstract

This is a case study presented by the University of Pittsburgh Department of Pathology in which a 22-year-old previously healthy woman was admitted to the hospital following a generalized tonic-clonic seizure. Visitors are given admission data, CT scan images as well as microscopic description and images in order to provide the opportunity to diagnose the patient. This is an excellent resource for students in the health sciences to familiarize themselves with using patient history and laboratory results to diagnose disease. It is also a helpful site for educators to use to introduce or test student learning in neuropathology.

Published
1999

80. Mutations in SUFU predispose to medulloblastoma

Author

Taylor, Michael D., primary, Liu, Ling, additional, Raffel, Corey, additional, Hui, Chi-chung, additional, Mainprize, Todd G., additional, Zhang, Xiaoyun, additional, Agatep, Ron, additional, Chiappa, Sharon, additional, Gao, Luzhang, additional, Lowrance, Anja, additional, Hao, Aihau, additional, Goldstein, Alisa M., additional, Stavrou, Theodora, additional, Scherer, Stephen W., additional, Dura, Wieslaw T., additional, Wainwright, Brandon, additional, Squire, Jeremy A., additional, Rutka, James T., additional, and Hogg, David, additional

Published
2002
Full Text
View/download PDF

85. Identification of differentially expressed and developmentally regulated genes in medulloblastoma using suppression subtraction hybridization.

Author

Naoki Yokota, Nicola Jane, Mainprize, Todd G., Taylor, Michael D., Kohata, Tomohiko, Loreto, Michael, Shigeo Ueda, Michael, Dura, Wieslaw, Grajkowska, Wiesia, Kuo, John S., and Rutka, James T.

Subjects
*MEDULLOBLASTOMA, *GENETIC regulation, *GENE expression, *NUCLEIC acid hybridization, *CEREBELLUM, *CYTOPLASMIC granules
Abstract

To increase our understanding of the molecular pathogenesis of medulloblastoma (MB), we utilized the technique of suppression subtractive hybridization (SSH) to identify genes that are dysregulated in MB when compared to cerebellum. SSH-enriched cDNA libraries from both human and Ptch+/- heterozygous murine MBs were generated by subtracting common cDNAs from corresponding non-neoplastic cerebellum. For the human classic MB library, total human cerebellar RNA was used as control tissue; for the Ptch+/- heterozygous MB, non-neoplastic cerebellum from an unaffected Ptch+/- littermate was used as the control. Through differential screening of these libraries, over 100 upregulated tumor cDNA fragments were isolated, sequenced and identified with the NCBI BLAST program. From these, we selected genes involved in cellular proliferation, antiapoptosis, and cerebellar differentiation for further analysis. Upregulated genes identified in the human MB library included Unc33-like protein (ULIP), SOX4, Neuronatin (NNAT), the mammalian homologue of Drosophila BarH-like 1(BARHL1), the nuclear matix protein NRP/B (ENC1), and the homeobox OTX2 gene. Genes found to be upregulated in the murine MB library included cyclin D2 (Ccnd2), thymopoietin (Tmpo), Musashi-1 (Msh1), protein phosphatase 2A inhibitor-2 (I-2pp2a), and Unc5h4(D). Using semiquantitative reverse transcription-polymerase chain reaction (RT-PCR), the mRNA expression levels for these genes were markedly higher in human MBs than in cerebellum. Western blot analysis was used to further confirm the overexpression of a subset of these genes at the protein level. Notch pathway overactivity was demonstrated in the TE671 MB cell line expressing high levels of MSH1 through HES1-Luciferase transfections. This study has revealed a panel of developmentally regulated genes that may be involved in the pathogenesis of MB.Oncogene (2004) 23, 3444-3453. doi:10.1038/sj.onc.1207475 Published online 5 April 2004 [ABSTRACT FROM AUTHOR]

Published
2004
Full Text
View/download PDF

86. 5th International Symposium on Focused Ultrasound

Author

Zaaroor, Menashe, Sinai, Alon, Goldsher, Dorit, Eran, Ayelet, Nassar, Maria, Schlesinger, Ilana, Parker, Jonathon, Ravikumar, Vinod, Ghanouni, Pejman, Stein, Sherman, Halpern, Casey, Krishna, Vibhor, Hargrove, Amelia, Agrawal, Punit, Changizi, Barbara, Bourekas, Eric, Knopp, Michael, Rezai, Ali, Mead, Brian, Kim, Namho, Mastorakos, Panagiotis, Suk, Jung Soo, Miller, Wilson, Klibanov, Alexander, Hanes, Justin, Price, Richard, Wang, Shutao, Olumolade, Oluyemi, Kugelman, Tara, Jackson-Lewis, Vernice, Karakatsani, Maria Eleni (Marilena), Han, Yang, Przedborski, Serge, Konofagou, Elisa, Hynynen, Kullervo, Aubert, Isabelle, Leinenga, Gerhard, Nisbet, Rebecca, Hatch, Robert, Van der Jeugd, Anneke, Evans, Harrison, Götz, Jürgen, Van der Jeugd, Ann, Fishman, Paul, Yarowsky, Paul, Frenkel, Victor, Wei-Bin, Shen, Nguyen, Ben, Sanchez, Carlos Sierra, Acosta, Camilo, Chen, Cherry, Wu, Shih-Ying, Aryal, Muna, Papademetriou, Iason T., Zhang, Yong-Zhi, Power, Chanikarn, McDannold, Nathan, Porter, Tyrone, Kovacs, Zsofia, Kim, Saejeong, Jikaria, Neekita, Qureshi, Farhan, Bresler, Michele, Frank, Joseph, Odéen, Henrik, Chiou, George, Snell, John, Todd, Nick, Madore, Bruno, Parker, Dennis, Pauly, Kim Butts, Marx, Mike, Jonathan, Sumeeth, Grissom, William, Arvanitis, Costas, Clement, Gregory, de Bever, Joshua, Payne, Allison, Christensen, Douglas, Maimbourg, Guillaume, Santin, Mathieu David, Houdouin, Alexandre, Lehericy, Stéphane, Tanter, Mickael, Aubry, Jean Francois, Federau, Christian, Werner, Beat, Paeng, Dong-Guk, Xu, Zhiyuan, Quigg, Anders, Eames, Matt, Jin, Changzhu, Everstine, Ashli, Sheehan, Jason, Lopes, M. Beatriz, Kassell, Neal, Drake, James, Price, Karl, Lustgarten, Lior, Sin, Vivian, Mougenot, Charles, Donner, Elizabeth, Tam, Emily, Hodaie, Mojgan, Waspe, Adam, Looi, Thomas, Pichardo, Samuel, Lee, Wonhye, Chung, Yong An, Jung, Yujin, Song, In-Uk, Yoo, Seung-Schik, Kim, Hyun-Chul, Lee, Jong-Hwan, Caskey, Charles, Zinke, Wolf, Cosman, Josh, Shuman, Jillian, Schall, Jeffrey, Aurup, Christian, Chen, Hong, Kamimura, Hermes, Carneiro, Antonio, Sun, Tao, Nazai, Navid, Patz, Sam, Livingstone, Margaret, Mainprize, Todd, Huang, Yuexi, Alkins, Ryan, Chapman, Martin, Perry, James, Lipsman, Nir, Bethune, Allison, Sahgal, Arjun, Trudeau, Maureen, Liu, Hao-Li, Hsu, Po-Hung, Wei, Kuo-Chen, Sutton, Jonathan, Alexander, Phillip, Miller, Eric, Kobus, Thiele, Carpentier, Alexandre, Canney, Michael, Vignot, Alexandre, Beccaria, Kevin, Leclercq, Delphine, Lafon, Cyril, Chapelon, Jean Yves, Hoang-Xuan, Khe, Delattre, Jean-Yves, Idbaih, Ahmed, Moore, David, Xu, Alexis, Schmitt, Paul, Foley, Jessica, Sukovich, Jonathan, Cain, Charles, Pandey, Aditya, Chaudhary, Neeraj, Camelo-Piragua, Sandra, Allen, Steven, Cannata, Jon, Teofilovic, Dejan, Bertolina, Jim, Hall, Timothy, Xu, Zhen, Grondin, Julien, Ferrera, Vincent, ter Haar, Gail, Mouratidis, Petros, Repasky, Elizabeth, Timbie, Kelsie, Badr, Lena, Campbell, Benjamin, McMichael, John, Buckner, Andrew, Prince, Jessica, Stevens, Aaron, Bullock, Timothy, Skalina, Karin, Guha, Chandan, Orsi, Franco, Bonomo, Guido, Vigna, Paolo Della, Mauri, Giovanni, Varano, Gianluca, Schade, George, Wang, Yak-Nam, Pillarisetty, Venu, Hwang, Joo Ha, Khokhlova, Vera, Bailey, Michael, Khokhlova, Tatiana, Sinilshchikov, Ilya, Yuldashev, Petr, Andriyakhina, Yulia, Kreider, Wayne, Maxwell, Adam, Sapozhnikov, Oleg, Partanen, Ari, Lundt, Jonathan, Preusser, Tobias, Haase, Sabrina, Bezzi, Mario, Jenne, Jürgen, Langø, Thomas, Midiri, Massimo, Mueller, Michael, Sat, Giora, Tanner, Christine, Zangos, Stephan, Guenther, Matthias, Melzer, Andreas, Menciassi, Arianna, Tognarelli, Selene, Cafarelli, Andrea, Diodato, Alessandro, Ciuti, Gastone, Rothluebbers, Sven, Schwaab, Julia, Strehlow, Jan, Mihcin, Senay, Tretbar, Steffen, Payen, Thomas, Palermo, Carmine, Sastra, Steve, Olive, Kenneth, Adams, Matthew, Salgaonkar, Vasant, Scott, Serena, Sommer, Graham, Diederich, Chris, Vidal-Jove, Joan, Perich, Eloi, Ruiz, Antonio, Velat, Manuela, Melodelima, David, Dupre, Aurelien, Vincenot, Jeremy, Yao, Chen, Perol, David, Rivoire, Michel, Tucci, Samantha, Mahakian, Lisa, Fite, Brett, Ingham, Elizabeth, Tam, Sarah, Hwang, Chang-il, Tuveson, David, Ferrara, Katherine, Scionti, Stephen, Chen, Lili, Cvetkovic, Dusica, Chen, Xiaoming, Gupta, Roohi, Wang, Bin, Ma, Charlie, Bader, Kenneth, Haworth, Kevin, Holland, Christy, Sanghvi, Narendra, Carlson, Roy, Chen, Wohsing, Chaussy, Christian, Thueroff, Stefan, Cesana, Claudio, Bellorofonte, Carlo, Wang, Qingguo, Wang, Han, Wang, Shengping, Zhang, Junhai, Bazzocchi, Alberto, Napoli, Alessandro, Staruch, Robert, Bing, Chenchen, Shaikh, Sumbul, Nofiele, Joris, Szczepanski, Debra, Staruch, Michelle Wodzak, Williams, Noelle, Laetsch, Theodore, Chopra, Rajiv, Rosenberg, Jarrett, Bitton, Rachelle, LeBlang, Suzanne, Meyer, Joshua, Hurwitz, Mark, Yarmolenko, Pavel, Celik, Haydar, Eranki, Avinash, Beskin, Viktoriya, Santos, Domiciano, Patel, Janish, Oetgen, Matthew, Kim, AeRang, Kim, Peter, Sharma, Karun, Chisholm, Alexander, Aleman, Dionne, Scipione, Roberto, Temple, Michael, Amaral, Joao Guilherme, Endre, Ruby, Lamberti-Pasculli, Maria, de Ruiter, Joost, Campbell, Fiona, Stimec, Jennifer, Gupta, Samit, Singh, Manoj, Hopyan, Sevan, Czarnota, Gregory, Brenin, David, Rochman, Carrie, Kovatcheva, Roussanka, Vlahov, Jordan, Zaletel, Katja, Stoinov, Julian, Bucknor, Matthew, Rieke, Viola, Shim, Jenny, Koral, Korgun, Lang, Brian, Wong, Carlos, Lam, Heather, Shinkov, Alexander, Hu, Jim, Zhang, Xi, Macoskey, Jonathan, Ives, Kimberly, Owens, Gabe, Gurm, Hitinder, Shi, Jiaqi, Pizzuto, Matthew, Dillon, Christopher, Christofferson, Ivy, Hilas, Elaine, Shea, Jill, Greillier, Paul, Ankou, Bénédicte, Bessière, Francis, Zorgani, Ali, Pioche, Mathieu, Kwiecinski, Wojciech, Magat, Julie, Melot-Dusseau, Sandrine, Lacoste, Romain, Quesson, Bruno, Pernot, Mathieu, Catheline, Stefan, Chevalier, Philippe, Marquet, Fabrice, Bour, Pierre, Vaillant, Fanny, Amraoui, Sana, Dubois, Rémi, Ritter, Philippe, Haïssaguerre, Michel, Hocini, Mélèze, Bernus, Olivier, Tebebi, Pamela, Burks, Scott, Milo, Blerta, Gertner, Michael, Zhang, Jimin, Wong, Andrew, Liu, Yu, Kheirolomoom, Azadeh, Seo, Jai, Watson, Katherine, Zhang, Hua, Foiret, Josquin, Borowsky, Alexander, Xu, Doudou, Thanou, Maya, Centelles, Miguell, Wright, Mike, Amrahli, Maral, So, Po-Wah, Gedroyc, Wladyslaw, Kneepkens, Esther, Heijman, Edwin, Keupp, Jochen, Weiss, Steffen, Nicolay, Klaas, Grüll, Holger, Nagle, Matthew, Nikolaeva, Anastasia V., Terzi, Marina E., Tsysar, Sergey A., Cunitz, Bryan, Mourad, Pierre, Downs, Matthew, Yang, Georgiana, Wang, Qi, Chen, Johnny, Farry, Justin, Dixon, Adam, Du, Zhongmin, Dhanaliwala, Ali, Hossack, John, Ranjan, Ashish, Maples, Danny, Wardlow, Rachel, Malayer, Jerry, Ramachandran, Akhilesh, Namba, Hirofumi, Kawasaki, Motohiro, Izumi, Masashi, Kiyasu, Katsuhito, Takemasa, Ryuichi, Ikeuchi, Masahiko, Ushida, Takahiro, Crake, Calum, Kothapalli, Satya V. V. N., Leighton, Wan, Wang, Zhaorui, Gach, H. Michael, Straube, William, Altman, Michael, Kim, Young-sun, Lim, Hyo Keun, Rhim, Hyunchul, van Breugel, Johanna, Braat, Manon, Moonen, Chrit, van den Bosch, Maurice, Ries, Mario, Marrocchio, Cristina, Dababou, Susan, Lee, Jae Young, Chung, Hyun Hoon, Kang, Soo Yeon, Kang, Kook Jin, Son, Keon Ho, Zhang, Dandan, Plata, Juan, Jones, Peter, Pascal-Tenorio, Aurea, Bouley, Donna, Bond, Aaron, Dallapiazza, Robert, Huss, Diane, Warren, Amy, Sperling, Scott, Gwinn, Ryder, Shah, Binit, Elias, W. Jeff, Curley, Colleen, Zhang, Ying, Negron, Karina, Abounader, Roger, Samiotaki, Gesthimani, Tu, Tsang-Wei, Papadakis, Georgios, Hammoud, Dima, Silvestrini, Matthew, Wolfram, Frank, Güllmar, Daniel, Reichenbach, Juergen, Hofmann, Denis, Böttcher, Joachim, Schubert, Harald, Lesser, Thomas G., Almquist, Scott, Camarena, Francisco, Jiménez-Gambín, Sergio, Jiménez, Noé, Chang, Jin Woo, Chaplin, Vandiver, Griesenauer, Rebekah, Miga, Michael, Ellens, Nicholas, Airan, Raag, Quinones-Hinojosa, Alfredo, Farahani, Keyvan, Feng, Xue, Fielden, Samuel, Zhao, Li, Wintermark, Max, Meyer, Craig, Guo, Sijia, Lu, Xin, Zhuo, Jiachen, Xu, Su, Gullapalli, Rao, Gandhi, Dheeraj, Brokman, Omer, Baek, Hongchae, Kim, Hyungmin, Leung, Steven, Webb, Taylor, Vykhodtseva, Natalia, Nguyen, Thai-Son, Park, Chang Kyu, Park, Sang Man, Jung, Na Young, Kim, Min Soo, Chang, Won Seok, Jung, Hyun Ho, Plaksin, Michael, Weissler, Yoni, Shoham, Shy, Kimmel, Eitan, Rosnitskiy, Pavel B., Krupa, Steve, Hazan, Eilon, Naor, Omer, Levy, Yoav, Maimon, Noam, Brosh, Inbar, Kahn, Itamar, Cahill, Jessica, Colas, Elodie Constanciel, Wydra, Adrian, Maev, Roman, Aly, Amirah, Sesenoglu-Laird, Ozge, Padegimas, Linas, Cooper, Mark, Waszczak, Barbara, Tehrani, Seruz, Slingluff, Craig, Larner, James, Andarawewa, Kumari, Ozhinsky, Eugene, Shah, Rutwik, Krug, Roland, Deckers, Roel, Linn, Sabine, Suelmann, Britt, Witkamp, Arjen, Vaessen, Paul, van Diest, Paul, Bartels, Lambertus W., Bos, Clemens, Borys, Nicolas, Storm, Gert, Van der Wall, Elsken, Farr, Navid, Alnazeer, Moez, Katti, Prateek, Wood, Bradford, Farrer, Alexis, Ferrer, Cyril, de Senneville, Baudouin Denis, van Stralen, Marijn, Liu, Jingfei, Leach, J. Kent, Zidowitz, Stephan, Lee, Hsin-Lun, Hsu, Fang-Chi, Kuo, Chia-Chun, Jeng, Shiu-Chen, Chen, Tung-Ho, Yang, Nai-Yi, Chiou, Jeng-Fong, Kao, Yi-tzu, Pan, Chia-Hsin, Wu, Jing-Fu, Tsai, Yi-Chieh, Johnson, Sara, Li, Dawei, He, Ye, Karakitsios, Ioannis, Schwenke, Michael, Demedts, Daniel, Xiao, Xu, Cavin, Ian, Minalga, Emilee, Merrill, Robb, Hadley, Rock, Ramaekers, Pascal, de Greef, Martijn, Shahriari, Kian, Parvizi, Mohammad Hossein, Asadnia, Kiana, Chamanara, Marzieh, Kamrava, Seyed Kamran, Chabok, Hamid Reza, Stein, Ruben, Muller, Sébastien, Tan, Jeremy, Zachiu, Cornel, Erasmus, Hans-Peter, Van Arsdell, Glen, Benson, Lee, Jang, Kee W., Angstadt, Mary, Lewis, Bobbi, McLean, Hailey, Hoogenboom, Martijn, Eikelenboom, Dylan, den Brok, Martijn, Wesseling, Pieter, Heerschap, Arend, Fütterer, Jurgen, Adema, Gosse, Wang, Kevin, Zhong, Pei, Joy, Joyce, McLeod, Helen, Kim, Harry, Lewis, Matthew, Ozilgen, Arda, Zahos, Peter, Coughlin, Dezba, Tang, Xinyan, Lotz, Jeff, Jedruszczuk, Kathleen, Gulati, Amitabh, Solomon, Stephen, Kaye, Elena, Mugler, John, Barbato, Gaetano, Scoarughi, Gian Luca, Corso, Cristiano, Gorgone, Alessandro, Migliore, Ilaria Giuseppina, Larrabee, Zachary, Hananel, Arik, Aubry, Jean-Francois, Negussie, Ayele, Wilson, Emmanuel, Seifabadi, Reza, Moon, Hyungwon, Kang, Jeeun, Sim, Changbeom, Chang, Jin Ho, Kim, Hyuncheol, Lee, Hak Jong, Sasaki, Noboru, Takiguchi, Mitsuyoshi, Sebeke, Lukas, Luo, Xi, de Jager, Bram, Heemels, Maurice, Abraham, Christopher, Curiel, Laura, Berriet, Rémi, Janát-Amsbury, Margit, Corea, Joseph, Ye, Patrick Peiyong, Arias, Ana Clauda, Lustig, Micheal, and Svedin, Bryant

Subjects
lcsh:Medical physics. Medical radiology. Nuclear medicine, Fibroadenomata, Cryo-ablation, High-intensity focused ultrasound, Ablative techniques, lcsh:R895-920, Review, Meeting Abstracts, Laser ablation
Abstract

Introduction Breast fibroadenomata (FAD) are benign lesions which occur in about 10 % of all women. Diagnosis is made by triple assessment (physical examination, imaging and/or histopathology/cytology). For a definitive diagnosis of FAD, the treatment is conservative unless the patient is symptomatic. For symptomatic patients, the lumps can be surgically excised or removed interventionally by vacuum-assisted mammotomy (VAM). Ablative techniques like high-intensity focused ultrasound (HIFU), cryo-ablation and laser ablation have also been used for the treatment of FAD, providing a minimally invasive treatment without scarring or poor cosmesis. This review summarises current trials using minimally invasive ablative techniques in the treatment of breast FAD. Methods A comprehensive review of studies using minimally invasive ablative techniques was performed. Results There are currently several trials completed or recruiting patients using HIFU, cryo-ablation and laser ablation in the treatment of breast FAD. The results look very promising but cannot be compared at this point due to heterogeneity between studies. Conclusion Minimally invasive ablative techniques like HIFU, cryo-ablation and laser ablation are promising in the treatment of breast FAD. Future trials should be randomised and contain larger numbers of patients to determine the effectiveness of ablative techniques with more precision.

Full Text
View/download PDF

87. High-Intensity Focused Ultrasound Ablation Therapy of Gliomas.

Author

Alkins RD and Mainprize TG

Subjects
Humans, Brain Neoplasms therapy, Glioma therapy, High-Intensity Focused Ultrasound Ablation methods
Abstract

Ultrasound in clinical medicine is most commonly associated with imaging, but can be harnessed to yield an array of biological effects, including thermal ablation of brain tumors. Therapeutic ultrasound has been studied for many years, but only within the last decade has the technology reached a point where it is safe and practical for clinical adoption. Using large, multi-element arrays, ultrasound can be focused through the skull, and combined with MRI for image guidance and real-time thermometry, to create lesions in the brain with millimeter accuracy. Using this technology, true non-invasive surgery can be accomplished with immediate tumor killing. Combining the ablative capabilities of focused ultrasound with its other unique effects, such as blood-brain barrier disruption and radiosensitization, may eventually result in change of the current glioma treatment paradigm., (© 2018 S. Karger AG, Basel.)

Published
2018
Full Text
View/download PDF

88. Endoscopic fenestration of a symptomatic cavum septum pellucidum: technical case report.

Author

Weyerbrock A, Mainprize T, and Rutka JT

Subjects
Brain Diseases diagnosis, Brain Diseases etiology, Child, Cysts complications, Cysts diagnosis, Headache diagnosis, Headache etiology, Humans, Hydrocephalus diagnosis, Hydrocephalus etiology, Hydrocephalus prevention & control, Male, Papilledema diagnosis, Papilledema etiology, Septum Pellucidum pathology, Treatment Outcome, Brain Diseases surgery, Cysts surgery, Endoscopy methods, Headache prevention & control, Papilledema prevention & control, Septum Pellucidum surgery
Abstract

Objective: Cysts of the septum pellucidum (CSPs) may become symptomatic because of obstruction of cerebrospinal fluid flow, resulting in increased intracranial pressure and hydrocephalus requiring surgical intervention. Endoscopic fenestration may be the most effective and least invasive technique to treat this pathological condition., Clinical Presentation: An 11-year-old boy sought treatment for frequent episodes of severe headache. On examination, he had papilledema. There was evidence on magnetic resonance imaging scans of a space-occupying CSP with obstructive hydrocephalus., Intervention: The endoscopic technique of fenestration of both lateral walls of an enlarged CSP via a left frontal approach under ultrasound guidance using a rigid endoscope was successful. After surgery, the patient became asymptomatic, his papilledema resolved, and magnetic resonance imaging scans demonstrated collapse of the walls of the CSP toward the midline., Conclusion: Neuroendoscopic fenestration should be strongly considered as the treatment of choice for symptomatic CSPs. This procedure alone can lead to complete resolution of clinical symptoms and hydrocephalus, can reduce the size of the CSP, and can obviate the need for an implantable cerebrospinal fluid shunt.

Published
2006
Full Text
View/download PDF

89. Imaging of murine brain tumors using a 1.5 Tesla clinical MRI system.

Author

van Furth WR, Laughlin S, Taylor MD, Salhia B, Mainprize T, Henkelman M, Cusimano MD, Ackerley C, and Rutka JT

Subjects
Animals, Brain Neoplasms pathology, Cell Line, Tumor, Echo-Planar Imaging instrumentation, Female, Humans, Mice, Mice, Nude, Brain Neoplasms diagnosis, Echo-Planar Imaging methods
Abstract

Background: In this study, we investigated the feasibility of using a 1.5 Tesla (T) clinical magnetic resonance imaging (MRI) system for in vivo assessment of three histopathologically different brain tumor models in mice., Methods: We selected mouse models in which tumor growth was observed in different intracranial compartments: Patched+/- heterozygous knock-out mice for tumor growth in the cerebellum (n = 5); U87 MG human astrocytoma cells xenografted to the frontal lobe of athymic mice (n = 15); and F5 (n = 15) or IOMM Lee (n = 15) human malignant meningioma cells xenotransplanted to the athymic mouse skull base or convexity. Mice were imaged using a small receiver surface coil and a clinical 1.5 T MRI system. T1- and fast spin echo T2-weighted image sequences were obtained in all animals. Gadolinium was injected via tail vein to better delineate the intracranial tumors. Twenty mice were followed by serial MRI to study tumor growth over time. In these mice, images were typically performed after tumor implantation, and at two week intervals. Mice were euthanized following their last imaging procedure, and their tumors were examined by histopathology. The histopathological preparations were then compared to the last MR images to correlate the imaging features with the pathology., Results: Magnetic resonance imaging delineated th tumors in the cerebellum, frontal lobes and skull base in all mouse models. The detection of intracranial tumors was enhanced with prio administration of gadolinium, and the limit of resolution of brain tumors in the mice was 1-2 mm3. Sequential images performed at different time intervals showed progressive tumor growth in all animals. The MR images of tumor size and location correlated accurately with th results of the histopathological analysis., Conclusion: Magnetic resonance imaging of murine brain tumors in different intracrania compartments is feasible with a 1.5 T clinical MR system and a specially designed surface coil. Tumors as small as 1-2 mm3 can be detecte with good image resolution. Mice harbouring nascent brain tumors can be followed sequentially by serial MR imaging. This may allow for a noninvasive means by which tumor growth can be measured, and novel therapies tested without resorting to sacrifice of the mice.

Published
2003
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results