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Your search keyword '"Maggard, Melinda A."' showing total 282 results
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282 results on '"Maggard, Melinda A."'

92. Long-Term Results of Pediatric Liver Transplantation

Author

Goss, John A., primary, Shackleton, Christopher R., additional, McDiarmid, Sue V., additional, Maggard, Melinda, additional, Swenson, Kim, additional, Seu, Philip, additional, Vargas, Jorge, additional, Martin, Martin, additional, Ament, Marvin, additional, Brill, Judith, additional, Harrison, Rick, additional, and Busuttil, Ronald W., additional

Published
1998
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95. FAS LIGAND GENE TRANSFER TO RENAL ALLOGRAFTS IN RATS

Author

Swenson, Kim M., primary, Ke, Bibo, additional, Wang, Tao, additional, Markowitz, Jay S., additional, Maggard, Melinda A., additional, Spear, Gerald S., additional, Imagawa, David K., additional, Goss, John A., additional, Busuttil, Ronald W., additional, and Seu, Philip, additional

Published
1998
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97. Do Young Colon Cancer Patients Have Worse Outcomes? World J. Surg. Vol. 28, No. 6, June 2004.

Author

O'Connell, Jessica B., Maggard, Melinda A., Liu, Jerome H., Etzioni, David A., Livingston, Edward H., and Ko, Clifford Y.

Subjects
*COLON surgery, *COLON cancer, *ONCOLOGIC surgery, *CANCER treatment, *CANCER patients, *ONCOLOGY, *CANCER
Abstract

Previous studies on colon cancer have noted rising incidence rates among young individuals and suggest that they may have more aggressive disease and worse 5-year survivals than their older counterparts. Our study uses a nationwide population-based cancer registry to analyze colon cancer presentations and outcomes in a young versus an older population. The records of patients with colon carcinoma were obtained from the Surveillance, Epidemiology, and End Results (SEER) national cancer database (1991–1999). Two cohorts based on age at diagnosis (20–40 years, n = 1334 vs. 60–80 years, n = 46,457) were compared for patient and tumor characteristics, treatment, and 5-year cancer-specific survival. A multivariate Cox regression was performed to identify predictors of survival. The young group had a higher proportion of black and Hispanic patients than did the older group (p < 0.001). Young patients had less stage I or II disease, more stage III or IV disease (p < 0.001), and worse-grade (poorly differentiated or anaplastic) tumors (p < 0.001). The 5-year stage-specific survival was similar for stage I and III disease (p = NS) but was significantly better for young patients with stage II and IV disease (p < 0.01). Using a nationally representative cancer registry, we found that young colon cancer patients tend to have later-stage and higher-grade tumors. However, they have equivalent or better 5-year cancer-specific survival compared to older patients. This population-based finding contradicts prior single-institution reports. [ABSTRACT FROM AUTHOR]

Published
2004
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98. Evaluating health utility in patients with melanoma, breast cancer, colon cancer, and lung cancer: a nationwide, population-based assessment1 <FN ID="FN1"><NO>1</NO>Presented at the annual meeting of the Association of VA Surgeons, Houston, TX, April 27–30, 2002.</FN>

Author

Ko, Clifford Y., Maggard, Melinda, and Livingston, Edward H.

Subjects
*CANCER treatment, *MELANOMA, *BREAST cancer diagnosis, *LUNG cancer
Abstract

: BackgroundUnderstanding the quality of life and health utility for cancer survivors is important; however, little data are available—particularly for long-term (>5 year) survivors. Using “health utility” scores as a proxy for quality of life may be advantageous because it is a single value. Utility scores range from 1.0 (perfect health) to 0 (death), and have been shown to be a good numerical summary of overall quality of life. Using a validated instrument for health utility (HALex), we calculated and report the scores of four different surgical cancers at multiple periods of follow-up, ranging from <1 year to >5 years after diagnosis.: MethodsPatients diagnosed with either breast, colon, melanoma, or lung cancer were studied using the 1998 National Health Information Survey. Responses to several validated questions were collected and health utility scores were calculated. Different time periods were measured; acute (<1 year), short term (1–5 years), and long term (>5 years). Once a single health utility score was calculated, multivariate analyses were performed to identify important predictors of better versus worse health utility scores.: ResultsThe total sample size was 692 (breast 377, colon 169, melanoma 92, lung 54). Mean ages at diagnosis for the cancer groups were 56, 61, 52, and 60 years, respectively. The mean health utility scores in the acute period after diagnosis were: breast 0.62, colon 0.67, melanoma 0.73, and lung 0.42. In this acute period, the mean utility score for lung cancer survivors was statistically lower versus the others in the acute period (P < 0.001). Although variable trends were noted in the short-term period, all cancers demonstrated an increase in mean scores in the long-term period; the percent increases were: breast 15% (P = 0.01), colon 12%, melanoma 7%, and lung 47%. Multivariate regression analyses identified important associations of health utility scores. Significant predictors of lower health utility included the presence of pain and the presence of co-existent diseases, most commonly joint problems, cardiovascular disease, and diabetes.: ConclusionsFor four surgical cancers in three time periods after diagnosis, health utility scores were lowest immediately after treatment and improved over time. Long-term (>5 year) survivors had the highest scores. Additionally, our analyses show that a part of health utility in this cohort is determined by the presence of pain and co-existent diseases, which are often items that can be improved by quality clinical care. [Copyright &y& Elsevier]

Published
2003
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99. RESPONSES.

Author

O'Connell, Jessica B., Maggard, Melinda A., and Ko, Clifford Y.

Subjects
*PERIODICALS, *LETTERS to the editor
Abstract

The article presents a response to the letter to the editor that concerns on the staging of colon cancer, published in the November 2005 issue.

Published
2005
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