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814 results on '"Ma, Jinzhu"'

66. Modulating the Electronic Structures of Pt on Pt/TiO2Catalyst for Boosting Toluene Oxidation

Author

Zhao, Qian, Zhang, Yan, He, Guangzhi, Ma, Jinzhu, Wang, Lian, and He, Hong

Abstract

Surface hydroxyl groups commonly exist on the catalyst and present a significant role in the catalytic reaction. Considering the lack of systematical researches on the effect of the surface hydroxyl group on reactant molecule activation, the PtOx/TiO2and PtOx–y(OH)y/TiO2catalysts were constructed and studied for a comprehensive understanding of the roles of the surface hydroxyl group in the oxidation of volatiles organic compounds. The PtOx/TiO2formed by a simple treatment with nitric acid presented greatly enhanced activity for toluene oxidation in which the turnover frequency of toluene oxidation on PtOx/TiO2was around 14 times as high as that on PtOx–y(OH)y/TiO2. Experimental and theoretical results indicated that adsorption/activation of toluene and reactivity of oxygen atom on the catalyst determined the toluene oxidation on the catalyst. The removal of surface hydroxyl groups on PtOxpromoted strong electronic coupling of the Pt 5d orbital in PtOxand C 2p orbital in toluene, facilitating the electron transfers from toluene to PtOxand subsequently the adsorption/activation of toluene. Additionally, the weak Pt–O bond promoted the activation of surface lattice oxygen, accelerating the deep oxidation of activated toluene. This study clarifies the inhibiting effect of surface hydroxyl groups on PtOxin toluene oxidation, providing a further understanding of hydrocarbon oxidation.

Published
2024
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77. A Unique Combination of Mn2+ and Aluminum Adjuvant Acted the Synergistic Effect.

Author

Cen, Yuwei, Chen, Shujie, Wei, Shuyu, Wu, Shuangshuang, Tao, Mingyang, Fu, Youxi, Wang, Yuncheng, Chen, Jing, Ma, Yixuan, Liu, Hongyan, Song, Baifen, Ma, Jinzhu, Wang, Beiyan, and Cui, Yudong

Subjects
IMMUNE response, IMMUNOCOMPETENCE, ALUMINUM hydroxide, ALUMINUM, INTERLEUKIN-17
Abstract

Introduction. The development of combinatorial adjuvants is a promising strategy to boost vaccination efficiency. Accumulating evidence indicates that manganese exerts strong immunocompetence and will become an enormous potential adjuvant. Here, we described a novel combination of Mn2+ plus aluminum hydroxide (AH) adjuvant that significantly exhibited the synergistic immune effect. Methodology. Initially, IsdB3 proteins as the immune-dominant fragment of IsdB proteins derived from Staphylococcus aureus (S. aureus) were prepared. IsdB3 proteins were identified by western blotting. Furthermore, we immunized C57/B6 mice with IsdB3 proteins plus Mn2+ and AH adjuvant. After the second immunization, the proliferation of lymphocytes was measured by the cell counting kit-8 (CCK-8) and the level of IFN-γ, IL-4, IL-10, and IL-17 cytokine from spleen lymphocytes in mice and generation of the antibodies against IsdB3 in serum was detected with ELISA, and the protective immune response was assessed through S. aureus challenge. Results. IsdB3 proteins plus Mn2+ and AH obviously stimulated the proliferation of spleen lymphocytes and increased the secretion of IFN-γ, IL-4, IL-10, and IL-17 cytokine in mice, markedly enhanced the generation of the antibodies against IsdB3 in serum, observably decreased bacterial load in organs, and greatly improved the survival rate of mice. Conclusion. These data showed that the combination of Mn2+ and AH significantly acted a synergistic effect, reinforced the immunogenicity of IsdB3, and offered a new strategy to increase vaccine efficiency. [ABSTRACT FROM AUTHOR]

Published
2024
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78. PEI‐PLGA nanoparticles significantly enhanced the immunogenicity of IsdB137‐361 proteins from Staphylococcus aureus

Author

Wang, Beiyan, primary, Dong, Yazun, additional, Cen, Yuwei, additional, Chen, Shujie, additional, Wen, Xue, additional, Liu, Kaiyue, additional, Wu, Shuangshuang, additional, Yu, Liquan, additional, Yu, Yongzhong, additional, Zhu, Zhanbo, additional, Ma, Jinzhu, additional, Song, Baifen, additional, and Cui, Yudong, additional

Published
2023
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84. A Machine Vision-Based Method for Tea Buds Segmentation and Picking Point Location Used on a Cloud Platform

Author

Ma, Jinzhu Lu, Zhiming Yang, Qianqian Sun, Zongmei Gao, and Wei

Subjects
tea buds picking, deep learning, image segmentation, cloud platform
Abstract

The segmentation and positioning of tea buds are the basis for intelligent picking robots to pick tea buds accurately. Tea images were collected in a complex environment, and median filtering was carried out to obtain tea bud images with smooth edges. Four semantic segmentation algorithms, U-Net, high-resolution network (HRNet_W18), fast semantic segmentation network (Fast-SCNN), and Deeplabv3+, were selected for processing images. The centroid of the tea buds and the image center of the minimum external rectangle were calculated. The farthest point from the centroid was extracted from the tea stalk orientation, which was the final picking point for tea buds. The experimental results showed that the mean intersection over union (mIoU) of HRNet_W18 was 0.81, and for a kernel with a median filter size of 3 × 3, the proportion of abnormal tea buds was only 11.6%. The average prediction accuracy of picking points with different tea stalk orientations was 57%. This study proposed a fresh tea bud segmentation and picking point location method based on a high-resolution network model. In addition, the cloud platform can be used for data sharing and real-time calculation of tea bud coordinates, reducing the computational burden of picking robots.

Published
2023
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85. Primary thyroid lymphoma -- report of four cases and literature review

Author

Sun, Haoying, Ma, Jinzhu, Chen, Yibo, and Liu, Ming

Subjects
Case Report
Abstract

Objective: This study aims to investigate the pathogenesis, clinical characteristics, diagnosis, treatment, and prognosis of primary thyroid lymphoma (PTL) for a better understanding of the disease and a more accurate PTL diagnosis, thereby preventing misdiagnosis and mistreatment. Methods: The clinical manifestations, biochemical examination, ultrasound examination, imaging examination, pathologic examination, diagnosis, and treatment of four PLT patients admitted to the Department of Thyroid and Breast Surgery of the Affiliated Hospital of Inner Mongolia Medical University from January 2010 to December 2020 were retrospectively analyzed. Results: Diffuse large B-cell lymphoma (DLBCL) expressing cluster of differentiation 20 (CD20) were detected in all four PTL patients. Hashimoto’s thyroiditis (HT) with increased anti-thyroglobulin antibodies (TGAb) occurred in two PTL patients, while antithyroid peroxidase autoantibody (TPOAb) was increased in three cases. All four patients underwent surgical and chemoradiotherapy treatments. Patients were without tumors during the follow-up ranging from 8 to 55 months. Conclusion: PTL is a primary extranodal lymphoma of the thyroid and is mainly derived from B-cell non-Hodgkin’s lymphoma. The pathogenesis of PTL remains unclear, but it is closely related to HT. Clinical diagnosis in this study was determined by either needle biopsy or surgical resection.

Published
2023

89. Construction and Analysis of ceRNA Networks Reveal the Key Genes Associated with Bovine Herpesvirus Type 1 Infection

Author

Song,Baifen, Huang,Yanmei, Ma,Jinzhu, Yu,Liquan, Yu,Yongzhong, Peng,Chen, Wu,Wenxue, Song,Baifen, Huang,Yanmei, Ma,Jinzhu, Yu,Liquan, Yu,Yongzhong, Peng,Chen, and Wu,Wenxue

Abstract

Baifen Song,1 Yanmei Huang,2 Jinzhu Ma,2 Liquan Yu,2 Yongzhong Yu,2 Chen Peng,1 Wenxue Wu1 1Key Laboratory of Animal Epidemiology and Zoonosis, College of Veterinary Medicine, China Agricultural University, Beijing, People’s Republic of China; 2The College of Life Science and Technology, Heilongjiang Bayi Agricultural University, Daqing, People’s Republic of ChinaCorrespondence: Wenxue Wu, Key Laboratory of Animal Epidemiology and Zoonosis, College of Veterinary Medicine, China Agricultural University, Beijing, 100193, People’s Republic of China, Tel/Fax +86-010-62733048, Email wuwenxue@cau.edu.cnBackground: Virus infection can cause the changes of lncRNA expression levels to regulate the interaction between virus and host, but the relationship between BHV-1 infection and lncRNA has not been reported.Methods: In this study, in order to reveal the molecular mechanism of RNA in BoHV-1 infection, the Madin-Darby bovine kidney (MDBK) cells were infected with BoHV-1, transcriptome sequencing were performed by next-generation sequencing at 18 h or 24 h or 33 h of viral infection and then based on the competitive endogenous RNA (ceRNA) theory, lncRNA-miRNA-mRNA networks were constructed using these high-throughput sequencing data. The network analysis, Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis were performed for functional annotation and exploration of ncRNA ceRNAs in BoHV-1 infection.Results: The results showed that 48 lncRNAs, 123 mRNAs and 20 miRNAs as differentially expressed genes, and the mitogen activated protein kinase (MAPK) pathway and calcium signaling pathway were significantly enriched in the ceRNA network. Some differentially expressed lncRNA genes were randomly selected for verification by RT-qPCR, and the results showed that their expression trend was consistent with the results of transcriptome sequencing data.Conclusion: This study revealed that BoHV-1 infection can affect the expression of RNAs in MDBK c

Published
2023

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