3,217 results on '"MARTINO G."'
Search Results
52. Multiobjective Optimization of Design of 4H-SiC Power MOSFETs for Specific Applications
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Bencherif, H., Dehimi, L., Pezzimenti, F., De Martino, G., and Della Corte, F. G.
- Published
- 2019
- Full Text
- View/download PDF
53. Impact of sexual maturity on the welfare of immunocastrated v. entire heavy female pigs
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Di Martino, G., Scollo, A., Garbo, A., Lega, F., Stefani, A.L., Vascellari, M., Natale, A., Zuliani, F., Zanardello, C., Tonon, F., and Bonfanti, L.
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- 2018
- Full Text
- View/download PDF
54. Effects of ozonation on the phenolic fraction of olive oil mill wastewater (OOMW) : a study case
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Ianni, A., Marone, E., Martino, C., Cichelli, A., and Martino, G.
- Published
- 2018
55. Digital human models for gait analysis: experimental validation of static force analysis tools under dynamic conditions
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Caporaso, T., Di Gironimo, G., Tarallo, A., De Martino, G., Di Ludovico, M., Lanzotti, A., Eynard, Benoit, editor, Nigrelli, Vincenzo, editor, Oliveri, Salvatore Massimo, editor, Peris-Fajarnes, Guillermo, editor, and Rizzuti, Sergio, editor
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- 2017
- Full Text
- View/download PDF
56. Hepatitis E virus infection in North Italy : high seroprevalence in swine herds and increased risk for swine workers
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MUGHINI-GRAS, L., ANGELONI, G., SALATA, C., VONESCH, N., D'AMICO, W., CAMPAGNA, G., NATALE, A., ZULIANI, F., CEGLIE, L., MONNE, I., VASCELLARI, M., CAPELLO, K., DI MARTINO, G., INGLESE, N., PALÙ, G., TOMAO, P., and BONFANTI, L.
- Published
- 2017
57. Neuromodulatory contribution to muscle force is reduced after 10 days of unilateral lower limb suspension
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Martino, G., primary, Valli, G., additional, Sarto, F., additional, Franchi, M., additional, Narici, M., additional, and De Vito, G., additional
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- 2023
- Full Text
- View/download PDF
58. Trend in HPV-related hospitalization in years 2015-21 in a Southern Italian Region
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Di Martino, G, primary, Cedrone, F, additional, Di Giovanni, P, additional, Trebbi, E, additional, Tognaccini, L, additional, Romano, F, additional, and Staniscia, T, additional
- Published
- 2023
- Full Text
- View/download PDF
59. Prevalence and features of delirium in older patients admitted to rehabilitation facilities
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Sidoli, Chiara, Zambon, Antonella, Tassistro, Elena, Rossi, Emanuela, Mossello, Enrico, Inzitari, Marco, Cherubini, Antonio, Marengoni, Alessandra, Morandi, Alessandro, Bellelli, Giuseppe, Tarasconi, A, Sella, M, Paternò, G, Faggian, G, Lucarelli, C, De Grazia, N, Alberto, C, Porcella, L, Nardiello, I, Chimenti, E, Zeni, M, Romairone, E, Minaglia, C, Ceccotti, C, Guerra, G, Mantovani, G, Monacelli, F, Candiani, T, Santolini, F, Rosso, M, Bono, V, Sibilla, S, Dal Santo, P, Ceci, M, Barone, P, Schirinzi, T, Formenti, A, Nastasi, G, Isaia, G, Gonella, D, Battuello, A, Casson, S, Calvani, D, Boni, F, Ciaccio, A, Rosa, R, Sanna, G, Manfredini, S, Cortese, L, Rizzo, M, Prestano, R, Greco, A, Lauriola, M, Gelosa, G, Piras, V, Arena, M, Cosenza, D, Bellomo, A, Lamontagna, M, Gabbani, L, Lambertucci, L, Perego, S, Parati, G, Basile, G, Gallina, V, Pilone, G, Giudice, C, Pietrogrande, L, Mosca, M, Corazzin, I, Rossi, P, Nunziata, V, D’Amico, F, Grippa, A, Giardini, S, Barucci, R, Cossu, A, Fiorin, L, Distefano, M, Lunardelli, M, Brunori, M, Ruffini, I, Abraham, E, Varutti, A, Fabbro, E, Catalano, A, Martino, G, Leotta, D, Marchet, A, Dell’Aquila, G, Scrimieri, A, Davoli, M, Casella, M, Cartei, A, Polidori, G, Brischetto, D, Motta, S, Saponara, R, Perrone, P, Russo, G, Del, D, Car, C, Pirina, T, Franzoni, S, Cotroneo, A, Ghiggia, F, Volpi, G, Menichetti, C, Bo, M, Panico, A, Calogero, P, Corvalli, G, Mauri, M, Lupia, E, Manfredini, R, Fabbian, F, March, A, Pedrotti, M, Veronesi, M, Strocchi, E, Borghi, C, Bianchetti, A, Crucitti, A, Difrancesco, V, Fontana, G, Geriatria, A, Bonanni, L, Barbone, F, Serrati, C, Ballardini, G, Simoncelli, M, Ceschia, G, Scarpa, C, Brugiolo, R, Fusco, S, Ciarambino, T, Biagini, C, Tonon, E, Porta, M, Venuti, D, Delsette, M, Poeta, M, Barbagallo, G, Trovato, G, Delitala, A, Arosio, P, Reggiani, F, Zuliani, G, Ortolani, B, Mussio, E, Girardi, A, Coin, A, Ruotolo, G, Castagna, A, Masina, M, Cimino, R, Pinciaroli, A, Tripodi, G, Cassadonte, F, Vatrano, M, Scaglione, L, Fogliacco, P, Muzzuilini, C, Romano, F, Padovani, A, Rozzini, L, Cagnin, A, Fragiacomo, F, Desideri, G, Liberatore, E, Bruni, A, Orsitto, G, Franco, M, Bonfrate, L, Bonetto, M, Pizio, N, Magnani, G, Cecchetti, G, Longo, A, Bubba, V, Marinan, L, Cotelli, M, Turla, M, Sessa, M, Abruzzi, L, Castoldi, G, Lovetere, D, Musacchio, C, Novello, M, Cavarape, A, Bini, A, Leonardi, A, Seneci, F, Grimaldi, W, Fimognari, F, Bambar, V, Saitta, A, Corica, F, Braga, M, Servi, Null, Ettorre, E, Camellini Bellelli, C G, Annoni, G, Marengoni, A, Crescenzo, A, Noro, G, Turco, R, Ponzetto, M, Giuseppe, L, Mazzei, B, Maiuri, G, Costaggiu, D, Damato, R, Formilan, M, Patrizia, G, Santuar, L, Gallucci, M, Paragona, M, Bini, P, Modica, D, Abati, C, Clerici, M, Barbera, I, Nigroimperiale, F, Manni, A, Votino, C, Castiglioni, C, Di, M, Degl’Innocenti, M, Moscatelli, G, Guerini, S, Casini, C, Dini, D, Denotariis, S, Bonometti, F, Paolillo, C, Riccardi, A, Tiozzo, A, Samysalamafahmy, A, Dibari, M, Vanni, S, Scarpa, A, Zara, D, Ranieri, P, Alessandro, M, Di, F, Pezzoni, D, Platto, C, D’Ambrosio, V, Ivaldi, C, Milia, P, Desalvo, F, Solaro, C, Strazzacappa, M, Cazzadori, M, Grasso, M, Troisi, E, Guerini, V, Bernardini, B, Corsini, C, Boffelli, S, Filippi, A, Delpin, K, Faraci, B, Bertoletti, E, Vannucci, M, Crippa, P, Malighetti, A, Caltagirone, C, Disant, S, Bettini, D, Maltese, F, Abruzzese, G, Cosimo, D, Azzini, M, Colombo, M, Procino, G, Fascendini, S, Barocco, F, Del, P, Mazzone, A, Cottino, M, Vezzadini, G, Avanzi, S, Brambilla, C, Orini, S, Sgrilli, F, Mello, A, Lombardi Muti, L E, Dijk, B, Fenu, S, Pes, C, Gareri, P, Passamonte, M, Rigo, R, Locusta, L, Caser, L, Rosso, G, Cesarini, S, Cozzi, R, Santini, C, Carbone, P, Cazzaniga, I, Lovati, R, Cantoni, A, Ranzani, P, Barra, D, Pompilio, G, Dimori, S, Cernesi, S, Riccò, C, Piazzolla, F, Capittini, E, Rota, C, Gottardi, F, Merla, L, Barelli, A, Millul, A, De, G, Morrone, G, Bigolari, M, Macchi, M, Zambon, F, Pizzorni, C, Dicasaleto, G, Menculini, G, Marcacci, M, Catanese, G, Sprini, D, Dicasalet, T, Bocci, M, Borga, S, Caironi, P, Cat, C, Cingolani, E, Avalli, L, Greco, G, Citerio, G, Gandini, L, Cornara, G, Lerda, R, Brazzi, L, Simeone, F, Caciorgna, M, Alampi, D, Francesconi, S, Beck, E, Antonini, B, Vettoretto, K, Meggiolaro, M, Garofalo, E, Notaro, S, Varutti, R, Bassi, F, Mistraletti, G, Marino, A, Rona, R, Rondelli, E, Riva, I, Cortegiani, A, Pistidda, L, D’Andrea, R, Querci, L, Gnesin, P, Todeschini, M, Lugano, M, Castelli, G, Ortolani, M, Cotoia, A, Maggiore, S, Ditizio, L, Graziani, R, Testa, I, Ferretti, E, Castioni, C, Lombardi, F, Caserta, R, Pasqua, M, Simoncini, S, Baccarini, F, Rispoli, M, Grossi, F, Cancelliere, L, Carnelli, M, Puccini, F, Biancofiore, G, Siniscalchi, A, Laici, C, Mossello, E, Torrini, M, Pasetti, G, Palmese, S, Oggioni, R, Mangani, V, Pini, S, Martelli, M, Rigo, E, Zuccalà, F, Cherri, A, Spina, R, Calamai, I, Petrucci, N, Caicedo, A, Ferri, F, Gritti, P, Brienza, N, Fonnesu, R, Dessena, M, Fullin, G, Saggioro, D, Sidoli, Chiara, Zambon, Antonella, Tassistro, Elena, Rossi, Emanuela, Mossello, Enrico, Inzitari, Marco, Cherubini, Antonio, Marengoni, Alessandra, Morandi, Alessandro, Bellelli, Giuseppe, A Tarasconi, M Sella, G Paternò, G Faggian, C Lucarelli, N De Grazia, C Alberto, L Porcella, I Nardiello, E Chimenti, M Zeni, E Romairone, C Minaglia, C Ceccotti, G Guerra, G Mantovani, F Monacelli, C Minaglia, T Candiani, F Santolini, C Minaglia, M Rosso, V Bono, S Sibilla, P Dal Santo, M Ceci, P Barone, T Schirinzi, A Formenti, G Nastasi, G Isaia, D Gonella, A Battuello, S Casson, D Calvani, F Boni, A Ciaccio, R Rosa, G Sanna, S Manfredini, L Cortese, M Rizzo, R Prestano, A Greco, M Lauriola, G Gelosa, V Piras, M Arena, D Cosenza, A Bellomo, M LaMontagna, L Gabbani, L Lambertucci, S Perego, G Parati, G Basile, V Gallina, G Pilone, C Giudice, L Pietrogrande, M Mosca, I Corazzin, P Rossi, V Nunziata, F D’Amico, A Grippa, S Giardini, R Barucci, A Cossu, L Fiorin, M Arena , M Distefano, M Lunardelli, M Brunori, I Ruffini, E Abraham, A Varutti, E Fabbro, A Catalano, G Martino, D Leotta, A Marchet, G Dell’Aquila, A Scrimieri, M Davoli, M Casella, A Cartei, G Polidori, G Basile, D Brischetto, S Motta, R Saponara, P Perrone, G Russo, D Del, C Car, T Pirina, S Franzoni, A Cotroneo, F Ghiggia, G Volpi, C Menichetti, M Bo, A Panico, P Calogero, G Corvalli, M Mauri, E Lupia, R Manfredini, F Fabbian, A March, M Pedrotti, M Veronesi, E Strocchi, C Borghi, A Bianchetti, A Crucitti, V DiFrancesco, G Fontana, A Geriatria, L Bonanni, F Barbone, C Serrati, G Ballardini, M Simoncelli, G Ceschia, C Scarpa, R Brugiolo, S Fusco, T Ciarambino, C Biagini, E Tonon, M Porta , D Venuti, M DelSette, M Poeta, G Barbagallo, G Trovato, A Delitala, P Arosio, F Reggiani, G Zuliani, B Ortolani, E Mussio, A Girardi, A Coin, G Ruotolo, A Castagna, M Masina, R Cimino, A Pinciaroli, G Tripodi, F Cassadonte, M Vatrano, L Scaglione, P Fogliacco, C Muzzuilini, F Romano, A Padovani, L Rozzini, A Cagnin, F Fragiacomo, G Desideri, E Liberatore, A Bruni, G Orsitto, M Franco, L Bonfrate, M Bonetto, N Pizio, G Magnani, G Cecchetti, A Longo, V Bubba, L Marinan, M Cotelli, M Turla, M Brunori, M Sessa, L Abruzzi, G Castoldi, D LoVetere, C Musacchio, M Novello, A Cavarape, A Bini, A Leonardi, F Seneci, W Grimaldi, F Seneci, F Fimognari, V Bambar, A Saitta, F Corica, M Braga, Servi, E Ettorre , C G Camellini Bellelli, G Annoni, A Marengoni, A Bruni, A Crescenzo, G Noro, R Turco, M Ponzetto, L Giuseppe, B Mazzei, G Maiuri, D Costaggiu, R Damato, E Fabbro, M Formilan, G Patrizia, L Santuar , M Gallucci, C Minaglia, M Paragona, P Bini, D Modica, C Abati, M Clerici, I Barbera, F NigroImperiale, A Manni, C Votino, C Castiglioni, M Di, M Degl’Innocenti, G Moscatelli, S Guerini, C Casini, D Dini, S DeNotariis, F Bonometti, C Paolillo, A Riccardi, A Tiozzo, A SamySalamaFahmy, A Riccardi, C Paolillo, M DiBari, S Vanni, A Scarpa, D Zara, P Ranieri, M Alessandro, P Calogero, G Corvalli, F Di, D Pezzoni, C Platto, V D’Ambrosio, C Ivaldi, P Milia, F DeSalvo, C Solaro, M Strazzacappa, M Bo, A Panico, M Cazzadori, M Bonetto, M Grasso, E Troisi, G Magnani, G Cecchetti, V Guerini, B Bernardini, C Corsini, S Boffelli, A Filippi, K Delpin, B Faraci, E Bertoletti, M Vannucci, P Crippa, A Malighetti, C Caltagirone, S DiSant, D Bettini, F Maltese, M Formilan, G Abruzzese, C Minaglia, D Cosimo, M Azzini, M Cazzadori, M Colombo, G Procino, S Fascendini, F Barocco, P Del, F D’Amico, A Grippa , A Mazzone, M Cottino, G Vezzadini, S Avanzi, C Brambilla, S Orini, F Sgrilli, A Mello, L E Lombardi Muti, B Dijk , S Fenu, C Pes, P Gareri, A Castagna, M Passamonte, R Rigo, L Locusta, L Caser, G Rosso, S Cesarini, R Cozzi, C Santini, P Carbone, I Cazzaniga, R Lovati, A Cantoni, P Ranzani, D Barra, G Pompilio, S Dimori, S Cernesi, C Riccò, F Piazzolla, E Capittini, C Rota, F Gottardi, L Merla, A Barelli, A Millul , G De, G Morrone, M Bigolari, C Minaglia, M Macchi, F Zambon, F D’Amico, F D’Amico, C Pizzorni, G DiCasaleto, G Menculini, M Marcacci, G Catanese, D Sprini, T DiCasalet, M Bocci, S Borga, P Caironi, C Cat, E Cingolani, L Avalli, G Greco, G Citerio, L Gandini, G Cornara, R Lerda, L Brazzi, F Simeone, M Caciorgna, D Alampi, S Francesconi, E Beck, B Antonini, K Vettoretto, M Meggiolaro, E Garofalo, A Bruni, S Notaro, R Varutti, F Bassi, G Mistraletti, A Marino, R Rona, E Rondelli, I Riva, A Cortegiani, L Pistidda, R D’Andrea, L Querci, P Gnesin, M Todeschini, M Lugano, G Castelli, M Ortolani, A Cotoia, S Maggiore, L DiTizio, R Graziani, I Testa, E Ferretti, C Castioni, F Lombardi, R Caserta, M Pasqua, S Simoncini, F Baccarini, M Rispoli, F Grossi, L Cancelliere, M Carnelli, F Puccini, G Biancofiore, A Siniscalchi, C Laici, E Mossello, M Torrini, G Pasetti, S Palmese, R Oggioni, V Mangani, S Pini, M Martelli, E Rigo, F Zuccalà , A Cherri, R Spina, I Calamai, N Petrucci, A Caicedo, F Ferri, P Gritti, N Brienza, R Fonnesu, M Dessena, G Fullin & D Saggioro, VU University medical center, Sidoli, C, Zambon, A, Tassistro, E, Rossi, E, Mossello, E, Inzitari, M, Cherubini, A, Marengoni, A, Morandi, A, Bellelli, G, Tarasconi, A, Sella, M, Paterno, G, Faggian, G, Lucarelli, C, De Grazia, N, Alberto, C, Porcella, L, Nardiello, I, Chimenti, E, Zeni, M, Romairone, E, Minaglia, C, Ceccotti, C, Guerra, G, Mantovani, G, Monacelli, F, Candiani, T, Santolini, F, Rosso, M, Bono, V, Sibilla, S, Dal Santo, P, Ceci, M, Barone, P, Schirinzi, T, Formenti, A, Nastasi, G, Isaia, G, Gonella, D, Battuello, A, Casson, S, Calvani, D, Boni, F, Ciaccio, A, Rosa, R, Sanna, G, Manfredini, S, Cortese, L, Rizzo, M, Prestano, R, Greco, A, Lauriola, M, Gelosa, G, Piras, V, Arena, M, Cosenza, D, Bellomo, A, Lamontagna, M, Gabbani, L, Lambertucci, L, Perego, S, Parati, G, Basile, G, Gallina, V, Pilone, G, Giudice, C, Pietrogrande, L, Mosca, M, Corazzin, I, Rossi, P, Nunziata, V, D'Amico, F, Grippa, A, Giardini, S, Barucci, R, Cossu, A, Fiorin, L, Distefano, M, Lunardelli, M, Brunori, M, Ruffini, I, Abraham, E, Varutti, A, Fabbro, E, Catalano, A, Martino, G, Leotta, D, Marchet, A, Dell'Aquila, G, Scrimieri, A, Davoli, M, Casella, M, Cartei, A, Polidori, G, Brischetto, D, Motta, S, Saponara, R, Perrone, P, Russo, G, Del, D, Car, C, Pirina, T, Franzoni, S, Cotroneo, A, Ghiggia, F, Volpi, G, Menichetti, C, Bo, M, Panico, A, Calogero, P, Corvalli, G, Mauri, M, Lupia, E, Manfredini, R, Fabbian, F, March, A, Pedrotti, M, Veronesi, M, Strocchi, E, Borghi, C, Bianchetti, A, Crucitti, A, Difrancesco, V, Fontana, G, Geriatria, A, Bonanni, L, Barbone, F, Serrati, C, Ballardini, G, Simoncelli, M, Ceschia, G, Scarpa, C, Brugiolo, R, Fusco, S, Ciarambino, T, Biagini, C, Tonon, E, Porta, M, Venuti, D, Delsette, M, Poeta, M, Barbagallo, G, Trovato, G, Delitala, A, Arosio, P, Reggiani, F, Zuliani, G, Ortolani, B, Mussio, E, Girardi, A, Coin, A, Ruotolo, G, Castagna, A, Masina, M, Cimino, R, Pinciaroli, A, Tripodi, G, Cassadonte, F, Vatrano, M, Scaglione, L, Fogliacco, P, Muzzuilini, C, Romano, F, Padovani, A, Rozzini, L, Cagnin, A, Fragiacomo, F, Desideri, G, Liberatore, E, Bruni, A, Orsitto, G, Franco, M, Bonfrate, L, Bonetto, M, Pizio, N, Magnani, G, Cecchetti, G, Longo, A, Bubba, V, Marinan, L, Cotelli, M, Turla, M, Sessa, M, Abruzzi, L, Castoldi, G, Lovetere, D, Musacchio, C, Novello, M, Cavarape, A, Bini, A, Leonardi, A, Seneci, F, Grimaldi, W, Fimognari, F, Bambar, V, Saitta, A, Corica, F, Braga, M, Servi, Ettorre, E, Camellini Bellelli, C, Annoni, G, Crescenzo, A, Noro, G, Turco, R, Ponzetto, M, Giuseppe, L, Mazzei, B, Maiuri, G, Costaggiu, D, Damato, R, Formilan, M, Patrizia, G, Santuar, L, Gallucci, M, Paragona, M, Bini, P, Modica, D, Abati, C, Clerici, M, Barbera, I, Nigroimperiale, F, Manni, A, Votino, C, Castiglioni, C, Di, M, Degl'Innocenti, M, Moscatelli, G, Guerini, S, Casini, C, Dini, D, Denotariis, S, Bonometti, F, Paolillo, C, Riccardi, A, Tiozzo, A, Samysalamafahmy, A, Dibari, M, Vanni, S, Scarpa, A, Zara, D, Ranieri, P, Alessandro, M, Di, F, Pezzoni, D, Platto, C, D'Ambrosio, V, Ivaldi, C, Milia, P, Desalvo, F, Solaro, C, Strazzacappa, M, Cazzadori, M, Grasso, M, Troisi, E, Guerini, V, Bernardini, B, Corsini, C, Boffelli, S, Filippi, A, Delpin, K, Faraci, B, Bertoletti, E, Vannucci, M, Crippa, P, Malighetti, A, Caltagirone, C, Disant, S, Bettini, D, Maltese, F, Abruzzese, G, Cosimo, D, Azzini, M, Colombo, M, Procino, G, Fascendini, S, Barocco, F, Del, P, Mazzone, A, Cottino, M, Vezzadini, G, Avanzi, S, Brambilla, C, Orini, S, Sgrilli, F, Mello, A, Lombardi Muti, L, Dijk, B, Fenu, S, Pes, C, Gareri, P, Passamonte, M, Rigo, R, Locusta, L, Caser, L, Rosso, G, Cesarini, S, Cozzi, R, Santini, C, Carbone, P, Cazzaniga, I, Lovati, R, Cantoni, A, Ranzani, P, Barra, D, Pompilio, G, Dimori, S, Cernesi, S, Ricco, C, Piazzolla, F, Capittini, E, Rota, C, Gottardi, F, Merla, L, Barelli, A, Millul, A, De, G, Morrone, G, Bigolari, M, Macchi, M, Zambon, F, Pizzorni, C, Dicasaleto, G, Menculini, G, Marcacci, M, Catanese, G, Sprini, D, Dicasalet, T, Bocci, M, Borga, S, Caironi, P, Cat, C, Cingolani, E, Avalli, L, Greco, G, Citerio, G, Gandini, L, Cornara, G, Lerda, R, Brazzi, L, Simeone, F, Caciorgna, M, Alampi, D, Francesconi, S, Beck, E, Antonini, B, Vettoretto, K, Meggiolaro, M, Garofalo, E, Notaro, S, Varutti, R, Bassi, F, Mistraletti, G, Marino, A, Rona, R, Rondelli, E, Riva, I, Cortegiani, A, Pistidda, L, D'Andrea, R, Querci, L, Gnesin, P, Todeschini, M, Lugano, M, Castelli, G, Ortolani, M, Cotoia, A, Maggiore, S, Ditizio, L, Graziani, R, Testa, I, Ferretti, E, Castioni, C, Lombardi, F, Caserta, R, Pasqua, M, Simoncini, S, Baccarini, F, Rispoli, M, Grossi, F, Cancelliere, L, Carnelli, M, Puccini, F, Biancofiore, G, Siniscalchi, A, Laici, C, Torrini, M, Pasetti, G, Palmese, S, Oggioni, R, Mangani, V, Pini, S, Martelli, M, Rigo, E, Zuccala, F, Cherri, A, Spina, R, Calamai, I, Petrucci, N, Caicedo, A, Ferri, F, Gritti, P, Brienza, N, Fonnesu, R, Dessena, M, Fullin, G, and Saggioro, D
- Subjects
Aging ,Disability ,Rehabilitation ,Delirium ,Dementia ,Physical restraint ,Cross-Sectional Studies ,Activities of Daily Living ,mental disorders ,Prevalence ,Humans ,Geriatrics and Gerontology ,Aged - Abstract
Background: Delirium is thought to be common across various settings of care; however, still little research has been conducted in rehabilitation. Aim: We investigated the prevalence of delirium, its features and motor subtypes in older patients admitted to rehabilitation facilities during the three editions of the “Delirium Day project”. Methods: We conducted a cross-sectional study in which 1237 older patients (age ≥ 65 years old) admitted to 50 Italian rehabilitation wards during the three editions of the “Delirium Day project” (2015 to 2017) were included. Delirium was evaluated through the 4AT and its motor subtype with the Delirium Motor Subtype Scale. Results: Delirium was detected in 226 patients (18%), and the most recurrent motor subtype was mixed (37%), followed by hypoactive (26%), hyperactive (21%) and non-motor one (16%). In a multivariate Poisson regression model with robust variance, factors associated with delirium were: disability in basic (PR 1.48, 95%CI: 1.17–1.9, p value 0.001) and instrumental activities of daily living (PR 1.58, 95%CI: 1.08–2.32, p value 0.018), dementia (PR 2.10, 95%CI: 1.62–2.73, p value < 0.0001), typical antipsychotics (PR 1.47, 95%CI: 1.10–1.95, p value 0.008), antidepressants other than selective serotonin reuptake inhibitors (PR 1.3, 95%CI: 1.02–1.66, p value 0.035), and physical restraints (PR 2.37, 95%CI: 1.68–3.36, p value < 0.0001). Conclusion: This multicenter study reports that 2 out 10 patients admitted to rehabilitations had delirium on the index day. Mixed delirium was the most prevalent subtype. Delirium was associated with unmodifiable (dementia, disability) and modifiable (physical restraints, medications) factors. Identification of these factors should prompt specific interventions aimed to prevent or mitigate delirium.
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- 2022
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60. Dietary supplementation with dried olive pomace in dairy cows modifies the composition of fatty acids and the aromatic profile in milk and related cheese
- Author
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Castellani, F., Vitali, A., Bernardi, N., Marone, E., Palazzo, F., Grotta, L., and Martino, G.
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- 2017
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61. Pockmark morphology and turbulent buoyant plumes at a submarine spring
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Buongiorno Nardelli, B., Budillon, F., Watteaux, R., Ciccone, F., Conforti, A., De Falco, G., Di Martino, G., Innangi, S., Tonielli, R., and Iudicone, D.
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- 2017
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62. Author Correction: Unrevealed genetic diversity of GII Norovirus in the swine population of North East Italy
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Cavicchio, L., Tassoni, L., Laconi, A., Cunial, G., Gagliazzo, L., Milani, A., Campalto, M., Di Martino, G., Forzan, M., Monne, I., and Beato, M. S.
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- 2020
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63. Unrevealed genetic diversity of GII Norovirus in the swine population of North East Italy
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Cavicchio, L., Tassoni, L., Laconi, A., Cunial, G., Gagliazzo, L., Milani, A., Campalto, M., Di Martino, G., Forzan, M., Monne, I., and Beato, M. S.
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- 2020
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64. Melting of a phase change material in a rectangular cavity in the presence of metallic fins.
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Naldi, C, Martino, G, Dongellini, M, Biserni, C, Morini, G L, and Lorente, S
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- 2024
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65. Economic and environmental assessment of agro-energy wood biomass supply chains
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Paolotti, L., Martino, G., Marchini, A., and Boggia, A.
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- 2017
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66. Factors associated with pre-slaughter mortality in turkeys and end of lay hens
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Di Martino, G., Capello, K., Russo, E., Mazzucato, M., Mulatti, P., Ferrè, N., Garbo, A., Brichese, M., Marangon, S., and Bonfanti, L.
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- 2017
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67. Groundwater Monitoring and Control by Using Electromagnetic Sensing Techniques
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Bavusi, M., Lapenna, V., Loperte, A., Gueguen, E., De Martino, G., Adurno, I., Catapano, I., Soldovieri, F., Barceló, Damià, Editor-in-chief, Kostianoy, Andrey G., Editor-in-chief, Scozzari, Andrea, editor, and Dotsika, Elissavet, editor
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- 2016
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68. In Operando Optical Tracking of Oxygen Vacancy Migration and Phase Change in few Nanometers Ferroelectric HZO Memories
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Jan, A, Rembert, T, Taper, S, Symonowicz, J, Strkalj, N, Moon, T, Lee, YS, Bae, H, Lee, HJ, Choe, DH, Heo, J, MacManus-Driscoll, J, Monserrat, B, Di Martino, G, Strkalj, N [0000-0001-8293-8577], Di Martino, G [0000-0001-5766-8384], and Apollo - University of Cambridge Repository
- Subjects
Biomaterials ,DF spectroscopy ,Electrochemistry ,phase changes ,fatigue ,HZO ultra-thin FeRAM ,wake-up ,Condensed Matter Physics ,Raman and PL ,Electronic, Optical and Magnetic Materials ,oxygen vacancies - Abstract
Funder: Gianna Angelopoulos Programme for Science, Technology, and Innovation, Funder: Cambridge Trust; Id: http://dx.doi.org/10.13039/501100003343, Ferroelectric materials offer a low‐energy, high‐speed alternative to conventional logic and memory circuitry. Hafnia‐based films have achieved single‐digit nm ferroelectricity, enabling further device miniaturization. However, they can exhibit nonideal behavior, specifically wake‐up and fatigue effects, leading to unpredictable performance variation over consecutive electronic switching cycles, preventing large‐scale commercialization. The origins are still under debate. Using plasmon‐enhanced spectroscopy, a non‐destructive technique sensitive to
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- 2023
69. Prevalence and features of delirium in older patients admitted to rehabilitation facilities: a multicenter study
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Sidoli, C, Zambon, A, Tassistro, E, Rossi, E, Mossello, E, Inzitari, M, Cherubini, A, Marengoni, A, Morandi, A, Bellelli, G, Tarasconi, A, Sella, M, Paterno, G, Faggian, G, Lucarelli, C, De Grazia, N, Alberto, C, Porcella, L, Nardiello, I, Chimenti, E, Zeni, M, Romairone, E, Minaglia, C, Ceccotti, C, Guerra, G, Mantovani, G, Monacelli, F, Candiani, T, Santolini, F, Rosso, M, Bono, V, Sibilla, S, Dal Santo, P, Ceci, M, Barone, P, Schirinzi, T, Formenti, A, Nastasi, G, Isaia, G, Gonella, D, Battuello, A, Casson, S, Calvani, D, Boni, F, Ciaccio, A, Rosa, R, Sanna, G, Manfredini, S, Cortese, L, Rizzo, M, Prestano, R, Greco, A, Lauriola, M, Gelosa, G, Piras, V, Arena, M, Cosenza, D, Bellomo, A, Lamontagna, M, Gabbani, L, Lambertucci, L, Perego, S, Parati, G, Basile, G, Gallina, V, Pilone, G, Giudice, C, Pietrogrande, L, Mosca, M, Corazzin, I, Rossi, P, Nunziata, V, D'Amico, F, Grippa, A, Giardini, S, Barucci, R, Cossu, A, Fiorin, L, Distefano, M, Lunardelli, M, Brunori, M, Ruffini, I, Abraham, E, Varutti, A, Fabbro, E, Catalano, A, Martino, G, Leotta, D, Marchet, A, Dell'Aquila, G, Scrimieri, A, Davoli, M, Casella, M, Cartei, A, Polidori, G, Brischetto, D, Motta, S, Saponara, R, Perrone, P, Russo, G, Del, D, Car, C, Pirina, T, Franzoni, S, Cotroneo, A, Ghiggia, F, Volpi, G, Menichetti, C, Bo, M, Panico, A, Calogero, P, Corvalli, G, Mauri, M, Lupia, E, Manfredini, R, Fabbian, F, March, A, Pedrotti, M, Veronesi, M, Strocchi, E, Borghi, C, Bianchetti, A, Crucitti, A, Difrancesco, V, Fontana, G, Geriatria, A, Bonanni, L, Barbone, F, Serrati, C, Ballardini, G, Simoncelli, M, Ceschia, G, Scarpa, C, Brugiolo, R, Fusco, S, Ciarambino, T, Biagini, C, Tonon, E, Porta, M, Venuti, D, Delsette, M, Poeta, M, Barbagallo, G, Trovato, G, Delitala, A, Arosio, P, Reggiani, F, Zuliani, G, Ortolani, B, Mussio, E, Girardi, A, Coin, A, Ruotolo, G, Castagna, A, Masina, M, Cimino, R, Pinciaroli, A, Tripodi, G, Cassadonte, F, Vatrano, M, Scaglione, L, Fogliacco, P, Muzzuilini, C, Romano, F, Padovani, A, Rozzini, L, Cagnin, A, Fragiacomo, F, Desideri, G, Liberatore, E, Bruni, A, Orsitto, G, Franco, M, Bonfrate, L, Bonetto, M, Pizio, N, Magnani, G, Cecchetti, G, Longo, A, Bubba, V, Marinan, L, Cotelli, M, Turla, M, Sessa, M, Abruzzi, L, Castoldi, G, Lovetere, D, Musacchio, C, Novello, M, Cavarape, A, Bini, A, Leonardi, A, Seneci, F, Grimaldi, W, Fimognari, F, Bambar, V, Saitta, A, Corica, F, Braga, M, Servi, Ettorre, E, Camellini Bellelli, C, Annoni, G, Crescenzo, A, Noro, G, Turco, R, Ponzetto, M, Giuseppe, L, Mazzei, B, Maiuri, G, Costaggiu, D, Damato, R, Formilan, M, Patrizia, G, Santuar, L, Gallucci, M, Paragona, M, Bini, P, Modica, D, Abati, C, Clerici, M, Barbera, I, Nigroimperiale, F, Manni, A, Votino, C, Castiglioni, C, Di, M, Degl'Innocenti, M, Moscatelli, G, Guerini, S, Casini, C, Dini, D, Denotariis, S, Bonometti, F, Paolillo, C, Riccardi, A, Tiozzo, A, Samysalamafahmy, A, Dibari, M, Vanni, S, Scarpa, A, Zara, D, Ranieri, P, Alessandro, M, Di, F, Pezzoni, D, Platto, C, D'Ambrosio, V, Ivaldi, C, Milia, P, Desalvo, F, Solaro, C, Strazzacappa, M, Cazzadori, M, Grasso, M, Troisi, E, Guerini, V, Bernardini, B, Corsini, C, Boffelli, S, Filippi, A, Delpin, K, Faraci, B, Bertoletti, E, Vannucci, M, Crippa, P, Malighetti, A, Caltagirone, C, Disant, S, Bettini, D, Maltese, F, Abruzzese, G, Cosimo, D, Azzini, M, Colombo, M, Procino, G, Fascendini, S, Barocco, F, Del, P, Mazzone, A, Cottino, M, Vezzadini, G, Avanzi, S, Brambilla, C, Orini, S, Sgrilli, F, Mello, A, Lombardi Muti, L, Dijk, B, Fenu, S, Pes, C, Gareri, P, Passamonte, M, Rigo, R, Locusta, L, Caser, L, Rosso, G, Cesarini, S, Cozzi, R, Santini, C, Carbone, P, Cazzaniga, I, Lovati, R, Cantoni, A, Ranzani, P, Barra, D, Pompilio, G, Dimori, S, Cernesi, S, Ricco, C, Piazzolla, F, Capittini, E, Rota, C, Gottardi, F, Merla, L, Barelli, A, Millul, A, De, G, Morrone, G, Bigolari, M, Macchi, M, Zambon, F, Pizzorni, C, Dicasaleto, G, Menculini, G, Marcacci, M, Catanese, G, Sprini, D, Dicasalet, T, Bocci, M, Borga, S, Caironi, P, Cat, C, Cingolani, E, Avalli, L, Greco, G, Citerio, G, Gandini, L, Cornara, G, Lerda, R, Brazzi, L, Simeone, F, Caciorgna, M, Alampi, D, Francesconi, S, Beck, E, Antonini, B, Vettoretto, K, Meggiolaro, M, Garofalo, E, Notaro, S, Varutti, R, Bassi, F, Mistraletti, G, Marino, A, Rona, R, Rondelli, E, Riva, I, Cortegiani, A, Pistidda, L, D'Andrea, R, Querci, L, Gnesin, P, Todeschini, M, Lugano, M, Castelli, G, Ortolani, M, Cotoia, A, Maggiore, S, Ditizio, L, Graziani, R, Testa, I, Ferretti, E, Castioni, C, Lombardi, F, Caserta, R, Pasqua, M, Simoncini, S, Baccarini, F, Rispoli, M, Grossi, F, Cancelliere, L, Carnelli, M, Puccini, F, Biancofiore, G, Siniscalchi, A, Laici, C, Torrini, M, Pasetti, G, Palmese, S, Oggioni, R, Mangani, V, Pini, S, Martelli, M, Rigo, E, Zuccala, F, Cherri, A, Spina, R, Calamai, I, Petrucci, N, Caicedo, A, Ferri, F, Gritti, P, Brienza, N, Fonnesu, R, Dessena, M, Fullin, G, Saggioro, D, Sidoli C., Zambon A., Tassistro E., Rossi E., Mossello E., Inzitari M., Cherubini A., Marengoni A., Morandi A., Bellelli G., Tarasconi A., Sella M., Paterno G., Faggian G., Lucarelli C., De Grazia N., Alberto C., Porcella L., Nardiello I., Chimenti E., Zeni M., Romairone E., Minaglia C., Ceccotti C., Guerra G., Mantovani G., Monacelli F., Candiani T., Santolini F., Rosso M., Bono V., Sibilla S., Dal Santo P., Ceci M., Barone P., Schirinzi T., Formenti A., Nastasi G., Isaia G., Gonella D., Battuello A., Casson S., Calvani D., Boni F., Ciaccio A., Rosa R., Sanna G., Manfredini S., Cortese L., Rizzo M., Prestano R., Greco A., Lauriola M., Gelosa G., Piras V., Arena M., Cosenza D., Bellomo A., LaMontagna M., Gabbani L., Lambertucci L., Perego S., Parati G., Basile G., Gallina V., Pilone G., Giudice C., Pietrogrande L., Mosca M., Corazzin I., Rossi P., Nunziata V., D'Amico F., Grippa A., Giardini S., Barucci R., Cossu A., Fiorin L., Distefano M., Lunardelli M., Brunori M., Ruffini I., Abraham E., Varutti A., Fabbro E., Catalano A., Martino G., Leotta D., Marchet A., Dell'Aquila G., Scrimieri A., Davoli M., Casella M., Cartei A., Polidori G., Brischetto D., Motta S., Saponara R., Perrone P., Russo G., Del D., Car C., Pirina T., Franzoni S., Cotroneo A., Ghiggia F., Volpi G., Menichetti C., Bo M., Panico A., Calogero P., Corvalli G., Mauri M., Lupia E., Manfredini R., Fabbian F., March A., Pedrotti M., Veronesi M., Strocchi E., Borghi C., Bianchetti A., Crucitti A., DiFrancesco V., Fontana G., Geriatria A., Bonanni L., Barbone F., Serrati C., Ballardini G., Simoncelli M., Ceschia G., Scarpa C., Brugiolo R., Fusco S., Ciarambino T., Biagini C., Tonon E., Porta M., Venuti D., DelSette M., Poeta M., Barbagallo G., Trovato G., Delitala A., Arosio P., Reggiani F., Zuliani G., Ortolani B., Mussio E., Girardi A., Coin A., Ruotolo G., Castagna A., Masina M., Cimino R., Pinciaroli A., Tripodi G., Cassadonte F., Vatrano M., Scaglione L., Fogliacco P., Muzzuilini C., Romano F., Padovani A., Rozzini L., Cagnin A., Fragiacomo F., Desideri G., Liberatore E., Bruni A., Orsitto G., Franco M., Bonfrate L., Bonetto M., Pizio N., Magnani G., Cecchetti G., Longo A., Bubba V., Marinan L., Cotelli M., Turla M., Sessa M., Abruzzi L., Castoldi G., LoVetere D., Musacchio C., Novello M., Cavarape A., Bini A., Leonardi A., Seneci F., Grimaldi W., Fimognari F., Bambar V., Saitta A., Corica F., Braga M., Ettorre E., Camellini Bellelli C. G., Annoni G., Crescenzo A., Noro G., Turco R., Ponzetto M., Giuseppe L., Mazzei B., Maiuri G., Costaggiu D., Damato R., Formilan M., Patrizia G., Santuar L., Gallucci M., Paragona M., Bini P., Modica D., Abati C., Clerici M., Barbera I., NigroImperiale F., Manni A., Votino C., Castiglioni C., Di M., Degl'Innocenti M., Moscatelli G., Guerini S., Casini C., Dini D., DeNotariis S., Bonometti F., Paolillo C., Riccardi A., Tiozzo A., SamySalamaFahmy A., DiBari M., Vanni S., Scarpa A., Zara D., Ranieri P., Alessandro M., Di F., Pezzoni D., Platto C., D'Ambrosio V., Ivaldi C., Milia P., DeSalvo F., Solaro C., Strazzacappa M., Cazzadori M., Grasso M., Troisi E., Guerini V., Bernardini B., Corsini C., Boffelli S., Filippi A., Delpin K., Faraci B., Bertoletti E., Vannucci M., Crippa P., Malighetti A., Caltagirone C., DiSant S., Bettini D., Maltese F., Abruzzese G., Cosimo D., Azzini M., Colombo M., Procino G., Fascendini S., Barocco F., Del P., Mazzone A., Cottino M., Vezzadini G., Avanzi S., Brambilla C., Orini S., Sgrilli F., Mello A., Lombardi Muti L. E., Dijk B., Fenu S., Pes C., Gareri P., Passamonte M., Rigo R., Locusta L., Caser L., Rosso G., Cesarini S., Cozzi R., Santini C., Carbone P., Cazzaniga I., Lovati R., Cantoni A., Ranzani P., Barra D., Pompilio G., Dimori S., Cernesi S., Ricco C., Piazzolla F., Capittini E., Rota C., Gottardi F., Merla L., Barelli A., Millul A., De G., Morrone G., Bigolari M., Macchi M., Zambon F., Pizzorni C., DiCasaleto G., Menculini G., Marcacci M., Catanese G., Sprini D., DiCasalet T., Bocci M., Borga S., Caironi P., Cat C., Cingolani E., Avalli L., Greco G., Citerio G., Gandini L., Cornara G., Lerda R., Brazzi L., Simeone F., Caciorgna M., Alampi D., Francesconi S., Beck E., Antonini B., Vettoretto K., Meggiolaro M., Garofalo E., Notaro S., Varutti R., Bassi F., Mistraletti G., Marino A., Rona R., Rondelli E., Riva I., Cortegiani A., Pistidda L., D'Andrea R., Querci L., Gnesin P., Todeschini M., Lugano M., Castelli G., Ortolani M., Cotoia A., Maggiore S., DiTizio L., Graziani R., Testa I., Ferretti E., Castioni C., Lombardi F., Caserta R., Pasqua M., Simoncini S., Baccarini F., Rispoli M., Grossi F., Cancelliere L., Carnelli M., Puccini F., Biancofiore G., Siniscalchi A., Laici C., Torrini M., Pasetti G., Palmese S., Oggioni R., Mangani V., Pini S., Martelli M., Rigo E., Zuccala F., Cherri A., Spina R., Calamai I., Petrucci N., Caicedo A., Ferri F., Gritti P., Brienza N., Fonnesu R., Dessena M., Fullin G., Saggioro D., Sidoli, C, Zambon, A, Tassistro, E, Rossi, E, Mossello, E, Inzitari, M, Cherubini, A, Marengoni, A, Morandi, A, Bellelli, G, Tarasconi, A, Sella, M, Paterno, G, Faggian, G, Lucarelli, C, De Grazia, N, Alberto, C, Porcella, L, Nardiello, I, Chimenti, E, Zeni, M, Romairone, E, Minaglia, C, Ceccotti, C, Guerra, G, Mantovani, G, Monacelli, F, Candiani, T, Santolini, F, Rosso, M, Bono, V, Sibilla, S, Dal Santo, P, Ceci, M, Barone, P, Schirinzi, T, Formenti, A, Nastasi, G, Isaia, G, Gonella, D, Battuello, A, Casson, S, Calvani, D, Boni, F, Ciaccio, A, Rosa, R, Sanna, G, Manfredini, S, Cortese, L, Rizzo, M, Prestano, R, Greco, A, Lauriola, M, Gelosa, G, Piras, V, Arena, M, Cosenza, D, Bellomo, A, Lamontagna, M, Gabbani, L, Lambertucci, L, Perego, S, Parati, G, Basile, G, Gallina, V, Pilone, G, Giudice, C, Pietrogrande, L, Mosca, M, Corazzin, I, Rossi, P, Nunziata, V, D'Amico, F, Grippa, A, Giardini, S, Barucci, R, Cossu, A, Fiorin, L, Distefano, M, Lunardelli, M, Brunori, M, Ruffini, I, Abraham, E, Varutti, A, Fabbro, E, Catalano, A, Martino, G, Leotta, D, Marchet, A, Dell'Aquila, G, Scrimieri, A, Davoli, M, Casella, M, Cartei, A, Polidori, G, Brischetto, D, Motta, S, Saponara, R, Perrone, P, Russo, G, Del, D, Car, C, Pirina, T, Franzoni, S, Cotroneo, A, Ghiggia, F, Volpi, G, Menichetti, C, Bo, M, Panico, A, Calogero, P, Corvalli, G, Mauri, M, Lupia, E, Manfredini, R, Fabbian, F, March, A, Pedrotti, M, Veronesi, M, Strocchi, E, Borghi, C, Bianchetti, A, Crucitti, A, Difrancesco, V, Fontana, G, Geriatria, A, Bonanni, L, Barbone, F, Serrati, C, Ballardini, G, Simoncelli, M, Ceschia, G, Scarpa, C, Brugiolo, R, Fusco, S, Ciarambino, T, Biagini, C, Tonon, E, Porta, M, Venuti, D, Delsette, M, Poeta, M, Barbagallo, G, Trovato, G, Delitala, A, Arosio, P, Reggiani, F, Zuliani, G, Ortolani, B, Mussio, E, Girardi, A, Coin, A, Ruotolo, G, Castagna, A, Masina, M, Cimino, R, Pinciaroli, A, Tripodi, G, Cassadonte, F, Vatrano, M, Scaglione, L, Fogliacco, P, Muzzuilini, C, Romano, F, Padovani, A, Rozzini, L, Cagnin, A, Fragiacomo, F, Desideri, G, Liberatore, E, Bruni, A, Orsitto, G, Franco, M, Bonfrate, L, Bonetto, M, Pizio, N, Magnani, G, Cecchetti, G, Longo, A, Bubba, V, Marinan, L, Cotelli, M, Turla, M, Sessa, M, Abruzzi, L, Castoldi, G, Lovetere, D, Musacchio, C, Novello, M, Cavarape, A, Bini, A, Leonardi, A, Seneci, F, Grimaldi, W, Fimognari, F, Bambar, V, Saitta, A, Corica, F, Braga, M, Servi, Ettorre, E, Camellini Bellelli, C, Annoni, G, Crescenzo, A, Noro, G, Turco, R, Ponzetto, M, Giuseppe, L, Mazzei, B, Maiuri, G, Costaggiu, D, Damato, R, Formilan, M, Patrizia, G, Santuar, L, Gallucci, M, Paragona, M, Bini, P, Modica, D, Abati, C, Clerici, M, Barbera, I, Nigroimperiale, F, Manni, A, Votino, C, Castiglioni, C, Di, M, Degl'Innocenti, M, Moscatelli, G, Guerini, S, Casini, C, Dini, D, Denotariis, S, Bonometti, F, Paolillo, C, Riccardi, A, Tiozzo, A, Samysalamafahmy, A, Dibari, M, Vanni, S, Scarpa, A, Zara, D, Ranieri, P, Alessandro, M, Di, F, Pezzoni, D, Platto, C, D'Ambrosio, V, Ivaldi, C, Milia, P, Desalvo, F, Solaro, C, Strazzacappa, M, Cazzadori, M, Grasso, M, Troisi, E, Guerini, V, Bernardini, B, Corsini, C, Boffelli, S, Filippi, A, Delpin, K, Faraci, B, Bertoletti, E, Vannucci, M, Crippa, P, Malighetti, A, Caltagirone, C, Disant, S, Bettini, D, Maltese, F, Abruzzese, G, Cosimo, D, Azzini, M, Colombo, M, Procino, G, Fascendini, S, Barocco, F, Del, P, Mazzone, A, Cottino, M, Vezzadini, G, Avanzi, S, Brambilla, C, Orini, S, Sgrilli, F, Mello, A, Lombardi Muti, L, Dijk, B, Fenu, S, Pes, C, Gareri, P, Passamonte, M, Rigo, R, Locusta, L, Caser, L, Rosso, G, Cesarini, S, Cozzi, R, Santini, C, Carbone, P, Cazzaniga, I, Lovati, R, Cantoni, A, Ranzani, P, Barra, D, Pompilio, G, Dimori, S, Cernesi, S, Ricco, C, Piazzolla, F, Capittini, E, Rota, C, Gottardi, F, Merla, L, Barelli, A, Millul, A, De, G, Morrone, G, Bigolari, M, Macchi, M, Zambon, F, Pizzorni, C, Dicasaleto, G, Menculini, G, Marcacci, M, Catanese, G, Sprini, D, Dicasalet, T, Bocci, M, Borga, S, Caironi, P, Cat, C, Cingolani, E, Avalli, L, Greco, G, Citerio, G, Gandini, L, Cornara, G, Lerda, R, Brazzi, L, Simeone, F, Caciorgna, M, Alampi, D, Francesconi, S, Beck, E, Antonini, B, Vettoretto, K, Meggiolaro, M, Garofalo, E, Notaro, S, Varutti, R, Bassi, F, Mistraletti, G, Marino, A, Rona, R, Rondelli, E, Riva, I, Cortegiani, A, Pistidda, L, D'Andrea, R, Querci, L, Gnesin, P, Todeschini, M, Lugano, M, Castelli, G, Ortolani, M, Cotoia, A, Maggiore, S, Ditizio, L, Graziani, R, Testa, I, Ferretti, E, Castioni, C, Lombardi, F, Caserta, R, Pasqua, M, Simoncini, S, Baccarini, F, Rispoli, M, Grossi, F, Cancelliere, L, Carnelli, M, Puccini, F, Biancofiore, G, Siniscalchi, A, Laici, C, Torrini, M, Pasetti, G, Palmese, S, Oggioni, R, Mangani, V, Pini, S, Martelli, M, Rigo, E, Zuccala, F, Cherri, A, Spina, R, Calamai, I, Petrucci, N, Caicedo, A, Ferri, F, Gritti, P, Brienza, N, Fonnesu, R, Dessena, M, Fullin, G, Saggioro, D, Sidoli C., Zambon A., Tassistro E., Rossi E., Mossello E., Inzitari M., Cherubini A., Marengoni A., Morandi A., Bellelli G., Tarasconi A., Sella M., Paterno G., Faggian G., Lucarelli C., De Grazia N., Alberto C., Porcella L., Nardiello I., Chimenti E., Zeni M., Romairone E., Minaglia C., Ceccotti C., Guerra G., Mantovani G., Monacelli F., Candiani T., Santolini F., Rosso M., Bono V., Sibilla S., Dal Santo P., Ceci M., Barone P., Schirinzi T., Formenti A., Nastasi G., Isaia G., Gonella D., Battuello A., Casson S., Calvani D., Boni F., Ciaccio A., Rosa R., Sanna G., Manfredini S., Cortese L., Rizzo M., Prestano R., Greco A., Lauriola M., Gelosa G., Piras V., Arena M., Cosenza D., Bellomo A., LaMontagna M., Gabbani L., Lambertucci L., Perego S., Parati G., Basile G., Gallina V., Pilone G., Giudice C., Pietrogrande L., Mosca M., Corazzin I., Rossi P., Nunziata V., D'Amico F., Grippa A., Giardini S., Barucci R., Cossu A., Fiorin L., Distefano M., Lunardelli M., Brunori M., Ruffini I., Abraham E., Varutti A., Fabbro E., Catalano A., Martino G., Leotta D., Marchet A., Dell'Aquila G., Scrimieri A., Davoli M., Casella M., Cartei A., Polidori G., Brischetto D., Motta S., Saponara R., Perrone P., Russo G., Del D., Car C., Pirina T., Franzoni S., Cotroneo A., Ghiggia F., Volpi G., Menichetti C., Bo M., Panico A., Calogero P., Corvalli G., Mauri M., Lupia E., Manfredini R., Fabbian F., March A., Pedrotti M., Veronesi M., Strocchi E., Borghi C., Bianchetti A., Crucitti A., DiFrancesco V., Fontana G., Geriatria A., Bonanni L., Barbone F., Serrati C., Ballardini G., Simoncelli M., Ceschia G., Scarpa C., Brugiolo R., Fusco S., Ciarambino T., Biagini C., Tonon E., Porta M., Venuti D., DelSette M., Poeta M., Barbagallo G., Trovato G., Delitala A., Arosio P., Reggiani F., Zuliani G., Ortolani B., Mussio E., Girardi A., Coin A., Ruotolo G., Castagna A., Masina M., Cimino R., Pinciaroli A., Tripodi G., Cassadonte F., Vatrano M., Scaglione L., Fogliacco P., Muzzuilini C., Romano F., Padovani A., Rozzini L., Cagnin A., Fragiacomo F., Desideri G., Liberatore E., Bruni A., Orsitto G., Franco M., Bonfrate L., Bonetto M., Pizio N., Magnani G., Cecchetti G., Longo A., Bubba V., Marinan L., Cotelli M., Turla M., Sessa M., Abruzzi L., Castoldi G., LoVetere D., Musacchio C., Novello M., Cavarape A., Bini A., Leonardi A., Seneci F., Grimaldi W., Fimognari F., Bambar V., Saitta A., Corica F., Braga M., Ettorre E., Camellini Bellelli C. G., Annoni G., Crescenzo A., Noro G., Turco R., Ponzetto M., Giuseppe L., Mazzei B., Maiuri G., Costaggiu D., Damato R., Formilan M., Patrizia G., Santuar L., Gallucci M., Paragona M., Bini P., Modica D., Abati C., Clerici M., Barbera I., NigroImperiale F., Manni A., Votino C., Castiglioni C., Di M., Degl'Innocenti M., Moscatelli G., Guerini S., Casini C., Dini D., DeNotariis S., Bonometti F., Paolillo C., Riccardi A., Tiozzo A., SamySalamaFahmy A., DiBari M., Vanni S., Scarpa A., Zara D., Ranieri P., Alessandro M., Di F., Pezzoni D., Platto C., D'Ambrosio V., Ivaldi C., Milia P., DeSalvo F., Solaro C., Strazzacappa M., Cazzadori M., Grasso M., Troisi E., Guerini V., Bernardini B., Corsini C., Boffelli S., Filippi A., Delpin K., Faraci B., Bertoletti E., Vannucci M., Crippa P., Malighetti A., Caltagirone C., DiSant S., Bettini D., Maltese F., Abruzzese G., Cosimo D., Azzini M., Colombo M., Procino G., Fascendini S., Barocco F., Del P., Mazzone A., Cottino M., Vezzadini G., Avanzi S., Brambilla C., Orini S., Sgrilli F., Mello A., Lombardi Muti L. E., Dijk B., Fenu S., Pes C., Gareri P., Passamonte M., Rigo R., Locusta L., Caser L., Rosso G., Cesarini S., Cozzi R., Santini C., Carbone P., Cazzaniga I., Lovati R., Cantoni A., Ranzani P., Barra D., Pompilio G., Dimori S., Cernesi S., Ricco C., Piazzolla F., Capittini E., Rota C., Gottardi F., Merla L., Barelli A., Millul A., De G., Morrone G., Bigolari M., Macchi M., Zambon F., Pizzorni C., DiCasaleto G., Menculini G., Marcacci M., Catanese G., Sprini D., DiCasalet T., Bocci M., Borga S., Caironi P., Cat C., Cingolani E., Avalli L., Greco G., Citerio G., Gandini L., Cornara G., Lerda R., Brazzi L., Simeone F., Caciorgna M., Alampi D., Francesconi S., Beck E., Antonini B., Vettoretto K., Meggiolaro M., Garofalo E., Notaro S., Varutti R., Bassi F., Mistraletti G., Marino A., Rona R., Rondelli E., Riva I., Cortegiani A., Pistidda L., D'Andrea R., Querci L., Gnesin P., Todeschini M., Lugano M., Castelli G., Ortolani M., Cotoia A., Maggiore S., DiTizio L., Graziani R., Testa I., Ferretti E., Castioni C., Lombardi F., Caserta R., Pasqua M., Simoncini S., Baccarini F., Rispoli M., Grossi F., Cancelliere L., Carnelli M., Puccini F., Biancofiore G., Siniscalchi A., Laici C., Torrini M., Pasetti G., Palmese S., Oggioni R., Mangani V., Pini S., Martelli M., Rigo E., Zuccala F., Cherri A., Spina R., Calamai I., Petrucci N., Caicedo A., Ferri F., Gritti P., Brienza N., Fonnesu R., Dessena M., Fullin G., and Saggioro D.
- Abstract
Background: Delirium is thought to be common across various settings of care; however, still little research has been conducted in rehabilitation. Aim: We investigated the prevalence of delirium, its features and motor subtypes in older patients admitted to rehabilitation facilities during the three editions of the “Delirium Day project”. Methods: We conducted a cross-sectional study in which 1237 older patients (age ≥ 65 years old) admitted to 50 Italian rehabilitation wards during the three editions of the “Delirium Day project” (2015 to 2017) were included. Delirium was evaluated through the 4AT and its motor subtype with the Delirium Motor Subtype Scale. Results: Delirium was detected in 226 patients (18%), and the most recurrent motor subtype was mixed (37%), followed by hypoactive (26%), hyperactive (21%) and non-motor one (16%). In a multivariate Poisson regression model with robust variance, factors associated with delirium were: disability in basic (PR 1.48, 95%CI: 1.17–1.9, p value 0.001) and instrumental activities of daily living (PR 1.58, 95%CI: 1.08–2.32, p value 0.018), dementia (PR 2.10, 95%CI: 1.62–2.73, p value < 0.0001), typical antipsychotics (PR 1.47, 95%CI: 1.10–1.95, p value 0.008), antidepressants other than selective serotonin reuptake inhibitors (PR 1.3, 95%CI: 1.02–1.66, p value 0.035), and physical restraints (PR 2.37, 95%CI: 1.68–3.36, p value < 0.0001). Conclusion: This multicenter study reports that 2 out 10 patients admitted to rehabilitations had delirium on the index day. Mixed delirium was the most prevalent subtype. Delirium was associated with unmodifiable (dementia, disability) and modifiable (physical restraints, medications) factors. Identification of these factors should prompt specific interventions aimed to prevent or mitigate delirium.
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- 2022
70. Practice patterns and 90-day treatment-related morbidity in early-stage cervical cancer
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Bogani, G, Donato, V, Scambia, G, Landoni, F, Ghezzi, F, Muzii, L, Panici, P, Raspagliesi, F, Casarin, J, Di Martino, G, Grassi, T, Perrone, A, De Iaco, P, Multinu, F, Berretta, R, Capozzi, V, Zupi, E, Centini, G, Pellegrino, A, Corso, S, Stevenazzi, G, Boschi, A, Comerci, G, Greco, P, Scutiero, G, Sopracordevole, F, Giorda, G, Fichera, M, Simoncini, T, Caretto, M, Sartori, E, Ferrari, F, Cianci, A, Sarpietro, G, Matarazzo, M, Giampaolino, P, Bifulco, G, Morelli, M, Dio, M, Ferrero, A, Biglia, N, Barra, F, Ferrero, S, Cianci, S, Chiantera, V, Sozzi, G, Ercoli, A, Schettini, S, Orlando, T, Cannone, F, Ettore, G, Puppo, A, Olearo, E, Leone Roberti Maggiore, U, Artuso, V, Palaia, I, Perniola, G, Tripodi, R, D'Auge, T, Cuccu, I, Fischetti, M, Santangelo, G, Casorelli, A, Giannini, A, D'Oria, O, Vizzielli, G, Restaino, S, Bergamini, A, Bocciolone, L, Plotti, F, Angioli, R, Mantovani, G, Ceccaroni, M, Cassini, C, Dominoni, M, Giambanco, L, Amodeo, S, Leo, L, Thommaset, R, Raimondo, D, Seracchioli, R, Malzoni, M, Falcone, F, Gorlero, F, Di Luca, M, Busato, E, Kilzie, S, Dell'Acqua, A, Scarfone, G, Vercellini, P, Petrillo, M, Capobianco, G, Ciavattini, A, Mereu, L, Scollo, P, Sorbi, F, Fambrini, M, Romano, F, Ricci, G, Trojano, G, Damiani, G, Consonni, R, Di Lorenzo, N, Lippolis, A, Tinelli, R, Aguzzoli, L, Mandato, V, Palomba, S, Tripodi, M, Calandra, D, Pellegrini, F, Zullo, F, Surico, D, Remorgida, V, Ruscitto, F, Beretta, P, Vizza, E, Bogani G., Donato V. D., Scambia G., Landoni F., Ghezzi F., Muzii L., Panici P. B., Raspagliesi F., Casarin J., Di Martino G., Grassi T., Perrone A. M., De Iaco P., Multinu F., Berretta R., Capozzi V. A., Zupi E., Centini G., Pellegrino A., Corso S., Stevenazzi G., Boschi A. C., Comerci G., Greco P., Scutiero G., Sopracordevole F., Giorda G., Fichera M., Simoncini T., Caretto M., Sartori E., Ferrari F., Cianci A., Sarpietro G., Matarazzo M. G., Giampaolino P., Bifulco G., Morelli M., Dio M. D., Ferrero A., Biglia N., Barra F., Ferrero S., Cianci S., Chiantera V., Sozzi G., Ercoli A., Schettini S., Orlando T., Cannone F. G., Ettore G., Puppo A., Olearo E., Leone Roberti Maggiore U., Artuso V., Palaia I., Perniola G., Tripodi R., D'Auge T. G., Cuccu I., Fischetti M., Santangelo G., Casorelli A., Giannini A., D'Oria O., Vizzielli G., Restaino S., Bergamini A., Bocciolone L., Plotti F., Angioli R., Mantovani G., Ceccaroni M., Cassini C., Dominoni M., Giambanco L., Amodeo S., Leo L., Thommaset R., Raimondo D., Seracchioli R., Malzoni M., Falcone F., Gorlero F., Di Luca M., Busato E., Kilzie S., Dell'Acqua A., Scarfone G., Vercellini P., Petrillo M., Capobianco G., Ciavattini A., Mereu L., Scollo P., Sorbi F., Fambrini M., Romano F., Ricci G., Trojano G., Damiani G. R., Consonni R., Di Lorenzo N., Lippolis A., Tinelli R., Aguzzoli L., Mandato V. D., Palomba S., Tripodi M., Calandra D., Pellegrini F., Zullo F., Surico D., Remorgida V., Ruscitto F., Beretta P., Vizza E., Bogani, G, Donato, V, Scambia, G, Landoni, F, Ghezzi, F, Muzii, L, Panici, P, Raspagliesi, F, Casarin, J, Di Martino, G, Grassi, T, Perrone, A, De Iaco, P, Multinu, F, Berretta, R, Capozzi, V, Zupi, E, Centini, G, Pellegrino, A, Corso, S, Stevenazzi, G, Boschi, A, Comerci, G, Greco, P, Scutiero, G, Sopracordevole, F, Giorda, G, Fichera, M, Simoncini, T, Caretto, M, Sartori, E, Ferrari, F, Cianci, A, Sarpietro, G, Matarazzo, M, Giampaolino, P, Bifulco, G, Morelli, M, Dio, M, Ferrero, A, Biglia, N, Barra, F, Ferrero, S, Cianci, S, Chiantera, V, Sozzi, G, Ercoli, A, Schettini, S, Orlando, T, Cannone, F, Ettore, G, Puppo, A, Olearo, E, Leone Roberti Maggiore, U, Artuso, V, Palaia, I, Perniola, G, Tripodi, R, D'Auge, T, Cuccu, I, Fischetti, M, Santangelo, G, Casorelli, A, Giannini, A, D'Oria, O, Vizzielli, G, Restaino, S, Bergamini, A, Bocciolone, L, Plotti, F, Angioli, R, Mantovani, G, Ceccaroni, M, Cassini, C, Dominoni, M, Giambanco, L, Amodeo, S, Leo, L, Thommaset, R, Raimondo, D, Seracchioli, R, Malzoni, M, Falcone, F, Gorlero, F, Di Luca, M, Busato, E, Kilzie, S, Dell'Acqua, A, Scarfone, G, Vercellini, P, Petrillo, M, Capobianco, G, Ciavattini, A, Mereu, L, Scollo, P, Sorbi, F, Fambrini, M, Romano, F, Ricci, G, Trojano, G, Damiani, G, Consonni, R, Di Lorenzo, N, Lippolis, A, Tinelli, R, Aguzzoli, L, Mandato, V, Palomba, S, Tripodi, M, Calandra, D, Pellegrini, F, Zullo, F, Surico, D, Remorgida, V, Ruscitto, F, Beretta, P, Vizza, E, Bogani G., Donato V. D., Scambia G., Landoni F., Ghezzi F., Muzii L., Panici P. B., Raspagliesi F., Casarin J., Di Martino G., Grassi T., Perrone A. M., De Iaco P., Multinu F., Berretta R., Capozzi V. A., Zupi E., Centini G., Pellegrino A., Corso S., Stevenazzi G., Boschi A. C., Comerci G., Greco P., Scutiero G., Sopracordevole F., Giorda G., Fichera M., Simoncini T., Caretto M., Sartori E., Ferrari F., Cianci A., Sarpietro G., Matarazzo M. G., Giampaolino P., Bifulco G., Morelli M., Dio M. D., Ferrero A., Biglia N., Barra F., Ferrero S., Cianci S., Chiantera V., Sozzi G., Ercoli A., Schettini S., Orlando T., Cannone F. G., Ettore G., Puppo A., Olearo E., Leone Roberti Maggiore U., Artuso V., Palaia I., Perniola G., Tripodi R., D'Auge T. G., Cuccu I., Fischetti M., Santangelo G., Casorelli A., Giannini A., D'Oria O., Vizzielli G., Restaino S., Bergamini A., Bocciolone L., Plotti F., Angioli R., Mantovani G., Ceccaroni M., Cassini C., Dominoni M., Giambanco L., Amodeo S., Leo L., Thommaset R., Raimondo D., Seracchioli R., Malzoni M., Falcone F., Gorlero F., Di Luca M., Busato E., Kilzie S., Dell'Acqua A., Scarfone G., Vercellini P., Petrillo M., Capobianco G., Ciavattini A., Mereu L., Scollo P., Sorbi F., Fambrini M., Romano F., Ricci G., Trojano G., Damiani G. R., Consonni R., Di Lorenzo N., Lippolis A., Tinelli R., Aguzzoli L., Mandato V. D., Palomba S., Tripodi M., Calandra D., Pellegrini F., Zullo F., Surico D., Remorgida V., Ruscitto F., Beretta P., and Vizza E.
- Abstract
Background: To evaluate the impact of the Laparoscopic Approach to Cervical Cancer (LACC) Trial on patterns of care and surgery-related morbidity in early-stage cervical cancer. Methods: This is a retrospective, a multi-institutional study evaluating 90-day surgery-related outcomes of patients undergoing treatment for early-stage cervical cancer before (period I: 01/01/2016–06/01/2018) and after (period II: 01/01/2019–06/01/2021) the publication of the results of the LACC trial. Results: Charts of 1295 patients were evaluated: 581 (44.9%) and 714 (55.1%) before and after the publication of the LACC trial, respectively. After the publication of the LACC trial, the number of patients treated with minimally invasive radical hysterectomy decreased from 64.9% to 30.4% (p < 0.001). Overall, 90-day complications occurred in 110 (18.9%) and 119 (16.6%) patients in the period I and period II, respectively (p = 0.795). Similarly, the number of severe (grade 3 or worse) complications did not differ between the two periods (38 (6.5%) vs. 37 (5.1%); p = 0.297). Overall and severe 90-day complications were consistent between periods even evaluating stage IA (p = 0.471), IB1 (p = 0.929), and IB2 (p = 0.074), separately. Conclusions: The present investigation highlighted that in referral centers the shift from minimally invasive to open radical hysterectomy does not influence 90-day surgery-related morbidity.
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- 2022
71. Advanced low grade serous ovarian cancer: A retrospective analysis of surgical and chemotherapeutic management in two high volume oncological centers
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Di Lorenzo, P, Conteduca, V, Scarpi, E, Adorni, M, Multinu, F, Garbi, A, Betella, I, Grassi, T, Bianchi, T, Di Martino, G, Amadori, A, Maniglio, P, Strada, I, Carinelli, S, Jaconi, M, Aletti, G, Zanagnolo, V, Maggioni, A, Savelli, L, De Giorgi, U, Landoni, F, Colombo, N, Fruscio, R, Di Lorenzo P., Conteduca V., Scarpi E., Adorni M., Multinu F., Garbi A., Betella I., Grassi T., Bianchi T., Di Martino G., Amadori A., Maniglio P., Strada I., Carinelli S., Jaconi M., Aletti G., Zanagnolo V., Maggioni A., Savelli L., De Giorgi U., Landoni F., Colombo N., Fruscio R., Di Lorenzo, P, Conteduca, V, Scarpi, E, Adorni, M, Multinu, F, Garbi, A, Betella, I, Grassi, T, Bianchi, T, Di Martino, G, Amadori, A, Maniglio, P, Strada, I, Carinelli, S, Jaconi, M, Aletti, G, Zanagnolo, V, Maggioni, A, Savelli, L, De Giorgi, U, Landoni, F, Colombo, N, Fruscio, R, Di Lorenzo P., Conteduca V., Scarpi E., Adorni M., Multinu F., Garbi A., Betella I., Grassi T., Bianchi T., Di Martino G., Amadori A., Maniglio P., Strada I., Carinelli S., Jaconi M., Aletti G., Zanagnolo V., Maggioni A., Savelli L., De Giorgi U., Landoni F., Colombo N., and Fruscio R.
- Abstract
Background: Low-grade serous ovarian cancer (LGSOC) is a rare entity with different behavior compared to high-grade serous (HGSOC). Because of its general low chemosensitivity, complete cytoreductive surgery with no residual disease is crucial in advanced stage LGSOC. We evaluated the impact of optimal cytoreduction on survival outcome both at first diagnosis and at recurrence. Methods: We retrospectively studied consecutive patients diagnosed with advanced LGSOCs who underwent cytoreductive surgery in two oncological centers from January 1994 to December 2018. Survival curves were estimated by the Kaplan–Meier method, and 95% confidence intervals (95% CI) were estimated using the Greenwood formula. Results: A total of 92 patients were included (median age was 47 years, IQR 35–64). The median overall survival (OS) was 142.3 months in patients with no residual disease (RD), 86.4 months for RD 1–10 mm and 35.2 months for RD >10 mm (p = 0.002). Progression-free survival (PFS) was inversely related to RD after primary cytoreductive surgery (RD = 0 vs RD = 1–10 mm vs RD >10 mm, p = 0.002). On multivariate analysis, RD 1–10 mm (HR = 2.30, 95% CI 1.30–4.06, p = 0.004), RD >10 mm (HR = 3.89, 95% CI 1.92–7.88, p = 0.0004), FIGO stage IV (p = 0.001), and neoadjuvant chemotherapy (NACT) (p = 0.010) were independent predictors of PFS. RD >10 mm (HR = 3.13, 95% CI 1.52–6.46, p = 0.004), FIGO stage IV (p <0.0001) and NACT (p = 0.030) were significantly associated with a lower OS. Conclusions: Optimal cytoreductive surgery improves survival outcomes in advanced stage LGSOCs. When complete debulking is impossible, a RD <10 mm confers better OS compared to an RD >10 mm in this setting of patients.
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- 2022
72. Neutrophils predominate the immune signature of cerebral thrombi in COVID-19 stroke patients
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Genchi, A, Semerano, A, Schwarz, G, Dell'Acqua, B, Gullotta, G, Sampaolo, M, Boeri, E, Quattrini, A, Sanvito, F, Diamanti, S, Bergamaschi, A, Grassi, S, Podini, P, Panni, P, Michelozzi, C, Simionato, F, Scomazzoni, F, Remida, P, Valvassori, L, Falini, A, Ferrarese, C, Michel, P, Saliou, G, Hajdu, S, Beretta, S, Roveri, L, Filippi, M, Strambo, D, Martino, G, Bacigaluppi, M, Genchi A., Semerano A., Schwarz G., Dell'Acqua B., Gullotta G. S., Sampaolo M., Boeri E., Quattrini A., Sanvito F., Diamanti S., Bergamaschi A., Grassi S., Podini P., Panni P., Michelozzi C., Simionato F., Scomazzoni F., Remida P., Valvassori L., Falini A., Ferrarese C., Michel P., Saliou G., Hajdu S., Beretta S., Roveri L., Filippi M., Strambo D., Martino G., Bacigaluppi M., Genchi, A, Semerano, A, Schwarz, G, Dell'Acqua, B, Gullotta, G, Sampaolo, M, Boeri, E, Quattrini, A, Sanvito, F, Diamanti, S, Bergamaschi, A, Grassi, S, Podini, P, Panni, P, Michelozzi, C, Simionato, F, Scomazzoni, F, Remida, P, Valvassori, L, Falini, A, Ferrarese, C, Michel, P, Saliou, G, Hajdu, S, Beretta, S, Roveri, L, Filippi, M, Strambo, D, Martino, G, Bacigaluppi, M, Genchi A., Semerano A., Schwarz G., Dell'Acqua B., Gullotta G. S., Sampaolo M., Boeri E., Quattrini A., Sanvito F., Diamanti S., Bergamaschi A., Grassi S., Podini P., Panni P., Michelozzi C., Simionato F., Scomazzoni F., Remida P., Valvassori L., Falini A., Ferrarese C., Michel P., Saliou G., Hajdu S., Beretta S., Roveri L., Filippi M., Strambo D., Martino G., and Bacigaluppi M.
- Abstract
Coronavirus disease 2019 (COVID-19) is associated with an increased risk of thrombotic events. Ischemic stroke in COVID-19 patients entails high severity and mortality rates. Here we aimed to analyze cerebral thrombi of COVID-19 patients with large vessel occlusion (LVO) acute ischemic stroke to expose molecular evidence for SARS-CoV-2 in the thrombus and to unravel any peculiar immune-thrombotic features. We conducted a systematic pathological analysis of cerebral thrombi retrieved by endovascular thrombectomy in patients with LVO stroke infected with COVID-19 (n = 7 patients) and non-covid LVO controls (n = 23). In thrombi of COVID-19 patients, the SARS-CoV-2 docking receptor ACE2 was mainly expressed in monocytes/macrophages and showed higher expression levels compared to controls. Using polymerase chain reaction and sequencing, we detected SARS-CoV-2 Clade20A, in the thrombus of one COVID-19 patient. Comparing thrombus composition of COVID-19 and control patients, we noted no overt differences in terms of red blood cells, fibrin, neutrophil extracellular traps (NETs), von Willebrand Factor (vWF), platelets and complement complex C5b-9. However, thrombi of COVID-19 patients showed increased neutrophil density (MPO+ cells) and a three-fold higher Neutrophil-to-Lymphocyte Ratio (tNLR). In the ROC analysis both neutrophils and tNLR had a good discriminative ability to differentiate thrombi of COVID-19 patients from controls. In summary, cerebral thrombi of COVID-19 patients can harbor SARS-CoV2 and are characterized by an increased neutrophil number and tNLR and higher ACE2 expression. These findings suggest neutrophils as the possible culprit in COVID-19-related thrombosis. Graphical Abstract: [Figure not available: see fulltext.]
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- 2022
73. 261 Staging of high-risk endometrial cancer with PET/CT and sentinel lymph node mapping algorithm
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Buda, A, Crivellaro, C, Guerra, L, De Bernardi, E, Di Martino, G, Paderno, M, Dell’Orto, F, Grassi, T, Magni, S, and Di Meo, ML
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- 2019
- Full Text
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74. 252 Comparison of two ultra-staging protocols for the detection of lymph node metastases in early stage cervical and endometrial cancer
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Buda, A, Grassi, T, Lamanna, M, De ponti, E, Perego, P, Di Martino, G, Dell’Orto, F, Bazzurini, L, Magni, S, Adorni, M, Paderno, M, and Landoni, F
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- 2019
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75. 17 Standard ultrastaging (SU) compared to one-step nucleic acid amplification (OSNA) for sentinel lymph nodemetastasis detection in endometrial cancer patients: a retrospective large cohort comparison
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Buda, A, Fanfani, F, Monterossi, G, Vecchione, F, La Fera, E, Adorni, M, Vicini, D, Gioé, A, Di Martino, G, De Ponti, E, Zannoni, GF, Perego, P, Landoni, F, and Scambia, G
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- 2019
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76. The CLEF-2022 CheckThat! Lab on Fighting the COVID-19 Infodemic and Fake News Detection
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Barrón-Cedeño, A., Nakov, P., Da, San, Martino, G., Alam, F., Struß, J.M., Mandl, T., Míguez, R., Barrón-Cedeño, A., Nakov, P., Da, San, Martino, G., Alam, F., Struß, J.M., Mandl, T., and Míguez, R.
- Abstract
44th European Conference on Information Retrieval, ECIR 2022 -- 10 April 2022 through 14 April 2022 -- 276459, The fifth edition of the CheckThat! Lab is held as part of the 2022 Conference and Labs of the Evaluation Forum (CLEF). The lab evaluates technology supporting various factuality tasks in seven languages: Arabic, Bulgarian, Dutch, English, German, Spanish, and Turkish. Task 1 focuses on disinformation related to the ongoing COVID-19 infodemic and politics, and asks to predict whether a tweet is worth fact-checking, contains a verifiable factual claim, is harmful to the society, or is of interest to policy makers and why. Task 2 asks to retrieve claims that have been previously fact-checked and that could be useful to verify the claim in a tweet. Task 3 is to predict the veracity of a news article. Tasks 1 and 3 are classification problems, while Task 2 is a ranking one. © 2022, The Author(s), under exclusive license to Springer Nature Switzerland AG., Qatar Foundation, QF; Qatar National Research Fund, QNRF; Hamad Bin Khalifa University, HBKU: NPRP13S-0206-200281
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- 2023
77. Overview of the CLEF–2023 CheckThat! Lab on Checkworthiness, Subjectivity, Political Bias, Factuality, and Authority of News Articles and Their Source
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Barrón-Cedeño, A., Galassi, A., Da, San, Martino, G., Nakov, P., Elsayed, T., Azizov, D., Alam, F., Barrón-Cedeño, A., Galassi, A., Da, San, Martino, G., Nakov, P., Elsayed, T., Azizov, D., and Alam, F.
- Abstract
Proceedings of the 14th International Conference of the Cross-Language Evaluation Forum for European Languages, CLEF 2023 -- 18 September 2023 through 21 September 2023 -- 300519, We describe the sixth edition of the CheckThat! lab, part of the 2023 Conference and Labs of the Evaluation Forum (CLEF). The five previous editions of CheckThat! focused on the main tasks of the information verification pipeline: check-worthiness, verifying whether a claim was fact-checked before, supporting evidence retrieval, and claim verification. In this sixth edition, we zoom into some new problems and for the first time we offer five tasks in seven languages: Arabic, Dutch, English, German, Italian, Spanish, and Turkish. Task 1 asks to determine whether an item —text or text plus image— is check-worthy. Task 2 aims to predict whether a sentence from a news article is subjective or not. Task 3 asks to assess the political bias of the news at the article and at the media outlet level. Task 4 focuses on the factuality of reporting of news media. Finally, Task 5 looks at identifying authorities in Twitter that could help verify a given target claim. For a second year, CheckThat! was the most popular lab at CLEF-2023 in terms of team registrations: 127 teams. About one-third of them (a total of 37) actually participated. © 2023, The Author(s), under exclusive license to Springer Nature Switzerland AG., 11S-1204-170060, 6-1-0611-19074, PE00000013, PNRRM4C2-Investimento 1.3; Qatar Foundation, QF; Qatar National Research Fund, QNRF, The work of F. Alam, M. Hasanain and W. Zaghouani is partially supported by NPRP 13S-0206-200281 and NPRP 14C-0916-210015 from the Qatar National Research Fund (a member of Qatar Foundation). The work of A. Galassi is supported by the European Commission NextGeneration EU programme, PNRRM4C2-Investimento 1.3, PE00000013-“FAIR” Spoke 8. The work of Fatima Haouari was supported by GSRA grant #GSRA6-1-0611-19074 from the Qatar National Research Fund. The work of Tamer Elsayed was made possible by NPRP grant #NPRP-11S-1204-170060 from the Qatar National Research Fund. The findings achieved herein are solely the responsibility of the authors.
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- 2023
78. Report on the 13th Conference and Labs of the Evaluation Forum (CLEF 2022)
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Barrón-Cedeño, A, Da San Martino, G, Esposti, M, Faggioli, G, Ferro, N, Hanbury, A, Macdonald, C, Pasi, G, Potthast, M, Sebastiani, F, Barrón-Cedeño, Alberto, Da San Martino, Giovanni, Esposti, Mirko Degli, Faggioli, Guglielmo, Ferro, Nicola, Hanbury, Allan, Macdonald, Craig, Pasi, Gabriella, Potthast, Martin, Sebastiani, Fabrizio, Barrón-Cedeño, A, Da San Martino, G, Esposti, M, Faggioli, G, Ferro, N, Hanbury, A, Macdonald, C, Pasi, G, Potthast, M, Sebastiani, F, Barrón-Cedeño, Alberto, Da San Martino, Giovanni, Esposti, Mirko Degli, Faggioli, Guglielmo, Ferro, Nicola, Hanbury, Allan, Macdonald, Craig, Pasi, Gabriella, Potthast, Martin, and Sebastiani, Fabrizio
- Abstract
This is a report on the thirteenth edition of the Conference and Labs of the Evaluation Forum (CLEF 2022), held on September 5--8, 2022, in Bologna, Italy. CLEF was a four-day hybrid event combining a conference and an evaluation forum. The conference featured keynotes by Benno Stein and Rita Cucchiara, and presentation of peer-reviewed research papers covering a wide range of topics, in addition to many posters. The evaluation forum consisted of fourteen labs: ARQMath, BioASQ, CheckThat!, ChEMU, eRisk, HIPE, iDPP, ImageCLEF, JokeR, LeQua, LifeCLEF, PAN, SimpleText, and Touché, addressing a wide range of tasks, media, languages, and ways to go beyond standard test collections.
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- 2023
79. Overview of the CLEF–2023 CheckThat! Lab on Checkworthiness, Subjectivity, Political Bias, Factuality, and Authority of News Articles and Their Source
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Alam, F., Elsayed, T., Galassi, A., Barrón-Cedeño, A., Azizov, D., Nakov, P., Da, San, Martino, G., Alam, F., Elsayed, T., Galassi, A., Barrón-Cedeño, A., Azizov, D., Nakov, P., and Da, San, Martino, G.
- Abstract
Proceedings of the 14th International Conference of the Cross-Language Evaluation Forum for European Languages, CLEF 2023 -- 18 September 2023 through 21 September 2023 -- 300519, We describe the sixth edition of the CheckThat! lab, part of the 2023 Conference and Labs of the Evaluation Forum (CLEF). The five previous editions of CheckThat! focused on the main tasks of the information verification pipeline: check-worthiness, verifying whether a claim was fact-checked before, supporting evidence retrieval, and claim verification. In this sixth edition, we zoom into some new problems and for the first time we offer five tasks in seven languages: Arabic, Dutch, English, German, Italian, Spanish, and Turkish. Task 1 asks to determine whether an item —text or text plus image— is check-worthy. Task 2 aims to predict whether a sentence from a news article is subjective or not. Task 3 asks to assess the political bias of the news at the article and at the media outlet level. Task 4 focuses on the factuality of reporting of news media. Finally, Task 5 looks at identifying authorities in Twitter that could help verify a given target claim. For a second year, CheckThat! was the most popular lab at CLEF-2023 in terms of team registrations: 127 teams. About one-third of them (a total of 37) actually participated. © 2023, The Author(s), under exclusive license to Springer Nature Switzerland AG., 11S-1204-170060, 6-1-0611-19074, PE00000013, PNRRM4C2-Investimento 1.3; Qatar Foundation, QF; Qatar National Research Fund, QNRF, The work of F. Alam, M. Hasanain and W. Zaghouani is partially supported by NPRP 13S-0206-200281 and NPRP 14C-0916-210015 from the Qatar National Research Fund (a member of Qatar Foundation). The work of A. Galassi is supported by the European Commission NextGeneration EU programme, PNRRM4C2-Investimento 1.3, PE00000013-“FAIR” Spoke 8. The work of Fatima Haouari was supported by GSRA grant #GSRA6-1-0611-19074 from the Qatar National Research Fund. The work of Tamer Elsayed was made possible by NPRP grant #NPRP-11S-1204-170060 from the Qatar National Research Fund. The findings achieved herein are solely the responsibility of the authors.
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- 2023
80. The CLEF-2022 CheckThat! Lab on Fighting the COVID-19 Infodemic and Fake News Detection
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Míguez, R., Mandl, T., Struß, J.M., Alam, F., Da, San, Martino, G., Nakov, P., Barrón-Cedeño, A., Míguez, R., Mandl, T., Struß, J.M., Alam, F., Da, San, Martino, G., Nakov, P., and Barrón-Cedeño, A.
- Abstract
44th European Conference on Information Retrieval, ECIR 2022 -- 10 April 2022 through 14 April 2022 -- 276459, The fifth edition of the CheckThat! Lab is held as part of the 2022 Conference and Labs of the Evaluation Forum (CLEF). The lab evaluates technology supporting various factuality tasks in seven languages: Arabic, Bulgarian, Dutch, English, German, Spanish, and Turkish. Task 1 focuses on disinformation related to the ongoing COVID-19 infodemic and politics, and asks to predict whether a tweet is worth fact-checking, contains a verifiable factual claim, is harmful to the society, or is of interest to policy makers and why. Task 2 asks to retrieve claims that have been previously fact-checked and that could be useful to verify the claim in a tweet. Task 3 is to predict the veracity of a news article. Tasks 1 and 3 are classification problems, while Task 2 is a ranking one. © 2022, The Author(s), under exclusive license to Springer Nature Switzerland AG., Qatar Foundation, QF; Qatar National Research Fund, QNRF; Hamad Bin Khalifa University, HBKU: NPRP13S-0206-200281
- Published
- 2023
81. MIND at SemEval-2023 Task 11: From Uncertain Predictions to Subjective Disagreement
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Ojha, AK, Dogruoz, AS, San Martino, G, Madabushi, HT, Kumar, R, Sartori, E, Rizzi, G, Astorino, A, Scalena, D, Rosso, P, Fersini, E, Rizzi G., Astorino A., Scalena D., Rosso P., Fersini E., Ojha, AK, Dogruoz, AS, San Martino, G, Madabushi, HT, Kumar, R, Sartori, E, Rizzi, G, Astorino, A, Scalena, D, Rosso, P, Fersini, E, Rizzi G., Astorino A., Scalena D., Rosso P., and Fersini E.
- Abstract
This paper describes the participation of the research laboratory MIND, at the University of Milano-Bicocca, in the SemEval 2023 task related to Learning With Disagreements (Le-Wi-Di). The main goal is to identify the level of agreement/disagreement from a collection of textual datasets with different characteristics in terms of style, language, and task. The proposed approach is grounded on the hypothesis that the disagreement between annotators could be grasped by the uncertainty that a model, based on several linguistic characteristics, could have on the prediction of a given gold label.
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- 2023
82. Factors influencing the presence of potentially explosive gases during colonoscopy: Results of the SATISFACTION study
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Carnovali, M., Spada, Cristiano, Uebel, P., Bocus, P., Cannizzaro, Rino, Cavallaro, Fabio, Cesana, Bruno Mario, Cesaro, Paola, Costamagna, Guido, Dipaolo, D., Ferrari, A. P., Hinkel, C., Kashin, S., Massella, A., Melnikova, E., Orsatti, A., Ponchon, T., Prada, A., Radaelli, F., Sferrazza, Silvia, Soru, P., Testoni, P. A., Tontini, G. E., Vecchi, M., Fiori, G., Adyshirin, Z. S., Amato, Arianna, Anesi, A., Arpurt, J. P., Attardo, S., Balzarini, M., Bellon, S., Benini, M., Blanc, P., Bonato, G., Bordin, D., Bravi, I., Bulanova, N., Bunkova, E., Cadoni, S., Carparelli, S., Chashkova, E. Y., Ciprandi, Guido, Ciuffini, Cristina, Codazzi, M., Elli, L., Fedorishina, O., Hartmann, D., Jakobs, R., Janke, D., Kamalova, O., Karpova, I., Khitaryan, A., Lombardo, V., Lovera, Mauro, Maiero, S., Manes, G., Martino, G., Merkulova, E., Mura, D., Mutignani, Massimiliano, Occhipinti, P., Pescarolo, M., Petruzziello, Lucio, Pioche, M., Pisani, Anna, Poltorykhina, E., Pretti, C., Puzzono, M., Realdon, S., Reiche, P., Roberto, P., Roman, K., Rondonotti, E., Schettino, M., Segato, S., Shishin, K., Spina, L., Stefania, M., Trovato, C., Valats, J. C., Vena, N., Veselov, V., Viale, E., Vollmar, J., Zavyalov, D., Zimmermann, Thomas Alexander, Spada C. (ORCID:0000-0002-5692-0960), Cannizzaro R., Cavallaro F., Cesana B. M., Cesaro P., Costamagna G. (ORCID:0000-0002-8100-2731), Sferrazza S., Amato A., Ciprandi G., Ciuffini C., Lovera M., Mutignani M. (ORCID:0000-0002-1272-4888), Petruzziello L., Pisani A., Zimmermann T., Carnovali, M., Spada, Cristiano, Uebel, P., Bocus, P., Cannizzaro, Rino, Cavallaro, Fabio, Cesana, Bruno Mario, Cesaro, Paola, Costamagna, Guido, Dipaolo, D., Ferrari, A. P., Hinkel, C., Kashin, S., Massella, A., Melnikova, E., Orsatti, A., Ponchon, T., Prada, A., Radaelli, F., Sferrazza, Silvia, Soru, P., Testoni, P. A., Tontini, G. E., Vecchi, M., Fiori, G., Adyshirin, Z. S., Amato, Arianna, Anesi, A., Arpurt, J. P., Attardo, S., Balzarini, M., Bellon, S., Benini, M., Blanc, P., Bonato, G., Bordin, D., Bravi, I., Bulanova, N., Bunkova, E., Cadoni, S., Carparelli, S., Chashkova, E. Y., Ciprandi, Guido, Ciuffini, Cristina, Codazzi, M., Elli, L., Fedorishina, O., Hartmann, D., Jakobs, R., Janke, D., Kamalova, O., Karpova, I., Khitaryan, A., Lombardo, V., Lovera, Mauro, Maiero, S., Manes, G., Martino, G., Merkulova, E., Mura, D., Mutignani, Massimiliano, Occhipinti, P., Pescarolo, M., Petruzziello, Lucio, Pioche, M., Pisani, Anna, Poltorykhina, E., Pretti, C., Puzzono, M., Realdon, S., Reiche, P., Roberto, P., Roman, K., Rondonotti, E., Schettino, M., Segato, S., Shishin, K., Spina, L., Stefania, M., Trovato, C., Valats, J. C., Vena, N., Veselov, V., Viale, E., Vollmar, J., Zavyalov, D., Zimmermann, Thomas Alexander, Spada C. (ORCID:0000-0002-5692-0960), Cannizzaro R., Cavallaro F., Cesana B. M., Cesaro P., Costamagna G. (ORCID:0000-0002-8100-2731), Sferrazza S., Amato A., Ciprandi G., Ciuffini C., Lovera M., Mutignani M. (ORCID:0000-0002-1272-4888), Petruzziello L., Pisani A., and Zimmermann T.
- Abstract
This study tested the hypothesis that bowel preparation with mannitol should not affect the colonic concentration of H2 and CH4. Therefore, the SATISFACTION study, an international, multicenter, randomized, parallel-group phase II–III study investigated this issue. The phase II dose-finding part of the study evaluated H2, CH4, and O2 concentrations in 179 patients randomized to treatment with 50 g, 100 g, or 150 g mannitol. Phase III of the study compared the presence of intestinal gases in 680 patients randomized (1:1) to receive mannitol 100 g in single dose or a standard split-dose 2 L polyethylene glycol (PEG)-Asc preparation (2 L PEG-Asc). Phase II results showed that mannitol did not influence the concentration of intestinal gases. During phase III, no patient in either group had H2 or CH4 concentrations above the critical thresholds. In patients with H2 and/or CH4 levels above detectable concentrations, the mean values were below the risk thresholds by at least one order of magnitude. The results also highlighted the effectiveness of standard washing and insufflation maneuvers in removing residual intestinal gases. In conclusion, bowel cleansing with mannitol was safe as the concentrations of H2 and CH4 were the same as those found in patients prepared with 2 L PEG-Asc. In both groups, the concentrations of gases were influenced more by the degree of cleansing achieved and the insufflation and washing maneuvers performed than by the preparation used for bowel cleansing. The trial protocol was registered with ClinicalTrials.gov (https://clinicaltrials.gov/ct2/show/NCT04759885) and with EudraCT (eudract_number: 2019-002856-18).
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- 2023
83. Neural stem cell transplantation in patients with progressive multiple sclerosis: an open-label, phase 1 study
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Genchi, A, Brambilla, E, Sangalli, F, Radaelli, M, Bacigaluppi, M, Furlan, R, Andolfo, A, Drago, D, Magagnotti, C, Scotti, G, Greco, R, Vezzulli, P, Ottoboni, L, Bonopane, M, Capilupo, D, Ruffini, F, Belotti, D, Cabiati, B, Cesana, S, Matera, G, Leocani, L, Martinelli, V, Moiola, L, Vago, L, Panina-Bordignon, P, Falini, A, Ciceri, F, Uglietti, A, Sormani, M, Comi, G, Battaglia, M, Rocca, M, Storelli, L, Pagani, E, Gaipa, G, Martino, G, Genchi, Angela, Brambilla, Elena, Sangalli, Francesca, Radaelli, Marta, Bacigaluppi, Marco, Furlan, Roberto, Andolfo, Annapaola, Drago, Denise, Magagnotti, Cinzia, Scotti, Giulia Maria, Greco, Raffaella, Vezzulli, Paolo, Ottoboni, Linda, Bonopane, Marco, Capilupo, Daniela, Ruffini, Francesca, Belotti, Daniela, Cabiati, Benedetta, Cesana, Stefania, Matera, Giada, Leocani, Letizia, Martinelli, Vittorio, Moiola, Lucia, Vago, Luca, Panina-Bordignon, Paola, Falini, Andrea, Ciceri, Fabio, Uglietti, Anna, Sormani, Maria Pia, Comi, Giancarlo, Battaglia, Mario Alberto, Rocca, Maria A, Storelli, Loredana, Pagani, Elisabetta, Gaipa, Giuseppe, Martino, Gianvito, Genchi, A, Brambilla, E, Sangalli, F, Radaelli, M, Bacigaluppi, M, Furlan, R, Andolfo, A, Drago, D, Magagnotti, C, Scotti, G, Greco, R, Vezzulli, P, Ottoboni, L, Bonopane, M, Capilupo, D, Ruffini, F, Belotti, D, Cabiati, B, Cesana, S, Matera, G, Leocani, L, Martinelli, V, Moiola, L, Vago, L, Panina-Bordignon, P, Falini, A, Ciceri, F, Uglietti, A, Sormani, M, Comi, G, Battaglia, M, Rocca, M, Storelli, L, Pagani, E, Gaipa, G, Martino, G, Genchi, Angela, Brambilla, Elena, Sangalli, Francesca, Radaelli, Marta, Bacigaluppi, Marco, Furlan, Roberto, Andolfo, Annapaola, Drago, Denise, Magagnotti, Cinzia, Scotti, Giulia Maria, Greco, Raffaella, Vezzulli, Paolo, Ottoboni, Linda, Bonopane, Marco, Capilupo, Daniela, Ruffini, Francesca, Belotti, Daniela, Cabiati, Benedetta, Cesana, Stefania, Matera, Giada, Leocani, Letizia, Martinelli, Vittorio, Moiola, Lucia, Vago, Luca, Panina-Bordignon, Paola, Falini, Andrea, Ciceri, Fabio, Uglietti, Anna, Sormani, Maria Pia, Comi, Giancarlo, Battaglia, Mario Alberto, Rocca, Maria A, Storelli, Loredana, Pagani, Elisabetta, Gaipa, Giuseppe, and Martino, Gianvito
- Abstract
Innovative pro-regenerative treatment strategies for progressive multiple sclerosis (PMS), combining neuroprotection and immunomodulation, represent an unmet need. Neural precursor cells (NPCs) transplanted in animal models of multiple sclerosis have shown preclinical efficacy by promoting neuroprotection and remyelination by releasing molecules sustaining trophic support and neural plasticity. Here we present the results of STEMS, a prospective, therapeutic exploratory, non-randomized, open-label, single-dose-finding phase 1 clinical trial (NCT03269071, EudraCT 2016-002020-86), performed at San Raffaele Hospital in Milan, Italy, evaluating the feasibility, safety and tolerability of intrathecally transplanted human fetal NPCs (hfNPCs) in 12 patients with PMS (with evidence of disease progression, Expanded Disability Status Scale ≥6.5, age 18–55 years, disease duration 2–20 years, without any alternative approved therapy). The safety primary outcome was reached, with no severe adverse reactions related to hfNPCs at 2-year follow-up, clearly demonstrating that hfNPC therapy in PMS is feasible, safe and tolerable. Exploratory secondary analyses showed a lower rate of brain atrophy in patients receiving the highest dosage of hfNPCs and increased cerebrospinal fluid levels of anti-inflammatory and neuroprotective molecules. Although preliminary, these results support the rationale and value of future clinical studies with the highest dose of hfNPCs in a larger cohort of patients.
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- 2023
84. Synthesis and Characterization of Gd-Functionalized B4C Nanoparticles for BNCT Applications
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Vitali, A, Demichelis, M, Di Martino, G, Postuma, I, Bortolussi, S, Falqui, A, Milanese, C, Ferrara, C, Sommi, P, Anselmi-Tamburini, U, Demichelis, MP, Vitali, A, Demichelis, M, Di Martino, G, Postuma, I, Bortolussi, S, Falqui, A, Milanese, C, Ferrara, C, Sommi, P, Anselmi-Tamburini, U, and Demichelis, MP
- Abstract
Inorganic nanoparticles of boron-rich compounds represent an attractive alternative to boron-containing molecules, such as boronophenylalanine or boranes, for BNCT applications. This work describes the synthesis and biological activity of multifunctional boron carbide nanoparticles stabilized with polyacrylic acid (PAA) and a gadolinium (Gd)-rich solid phase. A fluorophore (DiI) was included in the PAA functionalization, allowing the confocal microscopy imaging of the nanoparticles. Analysis of the interaction and activity of these fluorescent Gd-containing B4C nanoparticles (FGdBNPs) with cultured cells was appraised using an innovative correlative microscopy approach combining intracellular neutron autoradiography, confocal, and SEM imaging. This new approach allows visualizing the cells, the FGdBNP, and the events deriving from the nuclear process in the same image. Quantification of 10B by neutron autoradiography in cells treated with FGdBNPs confirmed a significant accumulation of NPs with low levels of cellular toxicity. These results suggest that these NPs might represent a valuable tool for achieving a high boron concentration in tumoral cells.
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- 2023
85. Advanced low grade serous ovarian cancer: A retrospective analysis of surgical and chemotherapeutic management in two high volume oncological centers
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Di Lorenzo P., Conteduca V., Scarpi E., Adorni M., Multinu F., Garbi A., Betella I., Grassi T., Bianchi T., Di Martino G., Amadori A., Maniglio P., Strada I., Carinelli S., Jaconi M., Aletti G., Zanagnolo V., Maggioni A., Savelli L., De Giorgi U., Landoni F., Colombo N., Fruscio R., Di Lorenzo, P, Conteduca, V, Scarpi, E, Adorni, M, Multinu, F, Garbi, A, Betella, I, Grassi, T, Bianchi, T, Di Martino, G, Amadori, A, Maniglio, P, Strada, I, Carinelli, S, Jaconi, M, Aletti, G, Zanagnolo, V, Maggioni, A, Savelli, L, De Giorgi, U, Landoni, F, Colombo, N, and Fruscio, R
- Subjects
low-grade serous ovarian cancer ,Cancer Research ,Oncology ,primary cytoreduction ,adjuvant treatment ,residual disease ,secondary cytoreductive surgery ,neoadjuvant chemotherapy - Abstract
Simple summaryLow-grade serous ovarian cancer (LGSOC) represents an uncommon histotype of serous ovarian cancer (accounting for approximately 5% of all ovarian cancer) with a distinct behavior compared to its high-grade serous counterpart, characterized by a better prognosis and low response rate to chemotherapeutic agents. Similar to high-grade serous ovarian cancer, cytoreductive surgery is considered crucial for patient survival. This retrospective study aimed to analyze the outcomes of women affected by advanced stages (III–IV FIGO) of LGSOC from two high-volume oncological centers for ovarian neoplasm. In particular, we sought to evaluate the impact on survival outcomes of optimal cytoreductive surgery [i.e., residual disease (RD) BackgroundLow-grade serous ovarian cancer (LGSOC) is a rare entity with different behavior compared to high-grade serous (HGSOC). Because of its general low chemosensitivity, complete cytoreductive surgery with no residual disease is crucial in advanced stage LGSOC. We evaluated the impact of optimal cytoreduction on survival outcome both at first diagnosis and at recurrence.MethodsWe retrospectively studied consecutive patients diagnosed with advanced LGSOCs who underwent cytoreductive surgery in two oncological centers from January 1994 to December 2018. Survival curves were estimated by the Kaplan–Meier method, and 95% confidence intervals (95% CI) were estimated using the Greenwood formula.ResultsA total of 92 patients were included (median age was 47 years, IQR 35–64). The median overall survival (OS) was 142.3 months in patients with no residual disease (RD), 86.4 months for RD 1–10 mm and 35.2 months for RD >10 mm (p = 0.002). Progression-free survival (PFS) was inversely related to RD after primary cytoreductive surgery (RD = 0 vs RD = 1–10 mm vs RD >10 mm, p = 0.002). On multivariate analysis, RD 1–10 mm (HR = 2.30, 95% CI 1.30–4.06, p = 0.004), RD >10 mm (HR = 3.89, 95% CI 1.92–7.88, p = 0.0004), FIGO stage IV (p = 0.001), and neoadjuvant chemotherapy (NACT) (p = 0.010) were independent predictors of PFS. RD >10 mm (HR = 3.13, 95% CI 1.52–6.46, p = 0.004), FIGO stage IV (p ConclusionsOptimal cytoreductive surgery improves survival outcomes in advanced stage LGSOCs. When complete debulking is impossible, a RD 10 mm in this setting of patients.
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- 2022
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86. PO-1159 Proton and carbon ion therapy for skull base chordoma: 4-year mono-institutional experience
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Tubin, S., primary, Fossati, P., additional, Mock, U., additional, Lütgendorf-Caucig, C., additional, Flechl, B., additional, Pelak, M., additional, Carlino, A., additional, Martino, G., additional, Gora, J., additional, Stock, M., additional, and Hug, E., additional
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- 2023
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87. PO-1586 Immunomodulation by partial tumor irradiation using and carbon-ions: bystander and abscopal effects
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Tubin, S., primary, Fossati, P., additional, Martino, G., additional, Gora, J., additional, Carlino, A., additional, and Hug, E., additional
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- 2023
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88. PO-1097 Carbon ion radiotherapy (CIRT) at MedAustron: early clinical experience
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Fossati, P., primary, Stock, M., additional, Pelak, M., additional, Martino, G., additional, Tubin, S., additional, Góra, J., additional, Mock, U., additional, Daniel, M., additional, Georg, P., additional, Mumot, M., additional, Reschl, C., additional, Carlino, A., additional, and Hug, E., additional
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- 2023
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89. Fast Missing Source Contact Electrical Method Detection on Low Voltage TrenchFET Technology
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Cordiano, F., primary, Sanfilippo, D., additional, Stassi, A., additional, Mazza, B., additional, Perego, R., additional, Di Martino, G., additional, Calvagno, G., additional, Astuto, M., additional, Di Venere, F., additional, Pulvirenti, G., additional, and Patti, D., additional
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- 2023
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90. Increased muscle responses to balance perturbations in children with cerebral palsy can be explained by increased sensitivity to center of mass movement
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Willaert, J., primary, Martino, G., additional, Desloovere, K., additional, Van Campenhout, A., additional, Ting, L.H., additional, and De Groote, F, additional
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- 2023
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91. Investigation of creep phenomenon on composite material for bolt connections
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Scattina, A., Roncato, D., Belingardi, G., and Martino, G.
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- 2015
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92. Economic and environmental evaluation of transporting imported pellet: A case study
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Paolotti, L., Martino, G., Marchini, A., Pascolini, R., and Boggia, A.
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- 2015
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93. RF functional-based complete FA flow
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Fudoli, A., Martino, G., Scrofani, A., Aliberti, P., Gallo, D., and Cason, M.
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- 2015
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94. Varicocele and semen quality: a retrospective case–control study of 4230 patients from a single centre
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Pallotti, F., Paoli, D., Carlini, T., Vestri, A. R., Martino, G., Lenzi, A., and Lombardo, F.
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- 2017
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95. Estimation of repair costs for RC and masonry residential buildings based on damage data collected by post-earthquake visual inspection
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De Martino, G., Di Ludovico, M., Prota, A., Moroni, C., Manfredi, G., and Dolce, M.
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- 2017
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96. Assessment of Maritime Erosion Index for Ionian-Lucanian Coast
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Greco, M., Martino, G., Lollino, Giorgio, editor, Manconi, Andrea, editor, Locat, Jacques, editor, Huang, Yu, editor, and Canals Artigas, Miquel, editor
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- 2014
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97. Reson SeaBat 8125 backscatter data as a tool for seabed characterization (Central Mediterranean, Southern Italy): Results from different processing approaches
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Innangi, S., Barra, M., Di Martino, G., Parnum, I.M., Tonielli, R., and Mazzola, S.
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- 2015
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98. Overview of the CLEF 2022 SimpleText Lab: Automatic Simplification of Scientific Texts
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Ermakova, L., SanJuan, E., Kamps, J., Huet, S., Ovchinnikova, I., Nurbakova, D., Araújo, S., Hannachi, R., Mathurin, E., Bellot, P., Barrón-Cedeño, A., Da San Martino, G., Degli Esposti, M., Sebastiani, F., Macdonald, C., Pasi, G., Hanbury, A., Potthast, M., Faggioli, G., Ferro, N., Héritages et Constructions dans le Texte et l'Image (HCTI), Université de Bretagne Sud (UBS)-Université de Brest (UBO)-Institut Brestois des Sciences de l'Homme et de la Société (IBSHS), Université de Brest (UBO), Laboratoire Informatique d'Avignon (LIA), Avignon Université (AU)-Centre d'Enseignement et de Recherche en Informatique - CERI, University of Amsterdam [Amsterdam] (UvA), ManPower Language Solution, Distribution, Recherche d'Information et Mobilité (DRIM), Laboratoire d'InfoRmatique en Image et Systèmes d'information (LIRIS), Université Lumière - Lyon 2 (UL2)-École Centrale de Lyon (ECL), Université de Lyon-Université de Lyon-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Institut National des Sciences Appliquées de Lyon (INSA Lyon), Université de Lyon-Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Centre National de la Recherche Scientifique (CNRS)-Université Lumière - Lyon 2 (UL2)-École Centrale de Lyon (ECL), Université de Lyon-Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Centre National de la Recherche Scientifique (CNRS), Universidade do Minho = University of Minho [Braga], Laboratoire d'Informatique et Systèmes (LIS), Aix Marseille Université (AMU)-Université de Toulon (UTLN)-Centre National de la Recherche Scientifique (CNRS), and ILLC (FGw)
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[INFO.INFO-CL]Computer Science [cs]/Computation and Language [cs.CL] - Abstract
Although citizens agree on the importance of objective scientific information, yet they tend to avoid scientific literature due to access restrictions, its complex language or their lack of prior background knowledge. Instead, they rely on shallow information on the web or social media often published for commercial or political incentives rather than the correctness and informational value. This paper presents an overview of the CLEF 2022 SimpleText track addressing the challenges of text simplification approaches in the context of promoting scientific information access, by providing appropriate data and benchmarks, and creating a community of IR and NLP researchers working together to resolve one of the greatest challenges of today. The track provides a corpus of scientific literature abstracts and popular science requests. It features three tasks. First, content selection (what is in, or out?) challenges systems to select passages to include in a simplified summary in response to a query. Second, complexity spotting (what is unclear?) given a passage and a query, aims to rank terms/concepts that are required to be explained for understanding this passage (definitions, context, applications). Third, text simplification (rewrite this!) given a query, asks to simplify passages from scientific abstracts while preserving the main content.
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- 2022
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99. An Analytical Formulation for the Correlation of Surface-Scattered Fields at Two Bistatic Radar Receivers
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Di Martino G., Di Simone A., Iodice A., Di Martino, G., Di Simone, A., and Iodice, A.
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Bistatic radar ,GNSS-R ,coherence - Abstract
We present an analytical formulation of the correlation of the electromagnetic fields scattered by a rough or gently undulating surface and measured at two spatially separated points. The latter may be the positions of two different bistatic radar sensors receiving the scattered field at the same time, as in bistatic synthetic aperture radar interferometry, or two positions occupied by a single moving receiver at two slightly different times, as in Global Navigation Satellite System Reflectometry. The scattering surface is modeled as randomly rough, and the Kirchhoff Approximation is employed to compute the scattered field. The obtained closed-form expression of the field correlation is substantially coincident with the one already available in literature for far-from-specular scattering directions; conversely, for close-to-specular directions, the obtained formulation shows that, as the surface correlation length increases, the degree of coherence smoothly increases from the value obtained with the expression available in literature for rough surfaces to a value close to unity for very gently undulating surfaces.
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- 2022
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100. Matching ecological transition and food security in the cereal sector: The role of farmers preferences on production contracts
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Ciliberti, S, Frascarelli, A, and Martino, G
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Global and Planetary Change ,Ecology ,NIE ,food security ,Horticulture ,Management, Monitoring, Policy and Law ,sustainability ,choice experiment ,transaction costs ,Italy ,contracts ,uncertainty ,Agronomy and Crop Science ,Food Science - Abstract
IntroductionUnder an increasing demand from citizen and public institutions, agri-food supply chains are requested to comply with stringent environmental requirements. Moreover, new sources of uncertainty related to pandemic and geo-political turbulences put further pressures on economic agents, calling for proper and resilient governance mechanisms. Under the lens of the Neo Institutional Economics, we focus on production contracts and their clauses which, in turn, perform different functions and contribute to allocate property and decision rights, in the attempt to conciliate sustainability and food security.MethodsIn this framework, contract design assumes a key importance. Thus, we analyze farmers' preferences for different contractual clauses in the cereal sector. A choice experiment is carried out among durum wheat producers in Italy and mixed logit estimations assuming heterogeneous preferences are performed.Results and discussionFindings provide interesting indications, revealing a strong farmers' willingness to adhere production contracts in exchange for price stability and knowledge transfer offered by technical assistance services. However, producers are not available to limit their decisional autonomy in unilateral agreement with buyers and they reveal a certain indifference to costly production techniques aimed to improve environmental sustainability.
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- 2023
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