Search

This CMOS microprocessor has performance of about 45MIPS at 50 MHz with about 300 mW power dissipation at 3.3 V power supply. It implements about 440 k transistors in a 25 mm/sup 2/ die fabricated by 0.41 /spl mu/m double metal CMOS. It is designed as a core processor for PDA applications, that require high speed graphical operation and digital signal processing functions as well as low power consumption from portability requirements.

DLC films formed by gas cluster ion beam (GCIB) assisted deposition were investigated by NEXAFS using synchrotron radiation.

In this paper, visual information recognition ability is examined with a game which simulates machine operation. First, the difference of visual information recognition of every operator is discussed, and the difference is clarified with the value Visual Information Dependence. Next, the viewpoint of the operator is examined with the eye mark camera in order to validate the value. Furthermore, the effective improvement in the skill of a low skilled person is tried with the method derived from the value.

Home Care Division of Fujisawa Pharmaceutical Co. Ltd. has been providing the local public with the following services: 1) providing aseptic medicines prescribed in the clean room, 2) renting the infusion fluid pumps, and 3) supporting the community cooperation in healthcare services. Last year, we surveyed questionnaires to the public users (patients and caretakers) of these services, in order to understand the actual status of patients after changing from conventional hospitalization to the home infusion therapy (HIT). From the results of our present survey, it was found that the patients and their family members had positively accepted HIT, while 61% of the HIT users exhibited a strong anxiety in their skills and methods of HIT. Moreover, it was also shown that 61% had other means of nursing and treatment in addition to HIT, indicating a great financial burden on the families. Among them, 69% of the HIT users considered that visiting nurses and primary care physicians were the best co-operators, and changed their conventional healthcare system (hospitalization) to HIT. However, the home caretakers showed a high anxiety in their skill in the home healthcare system, specifically HIT, which was generally highly dependent on the medical care, Thus, a good relationship and co-operation with visiting nurses and primary care physicians was one of the major factors for the users to decide to choose HIT instead of their old medical hospitalization. Therefore, in order to make HIT more useful and widely prevail, it is concluded that establishment of the co-operative systems within our local community, where visiting nurses and primary care physicians can easily provide the patients and their family with professional suggestions, advice and actual care whenever the home caretakers need them.

Testicular angiotensin converting enzyme (ACE) isozyme is likely to play important functional roles in male reproduction. Several studies have shown that ACE is released from human spermatozoa during capacitation and that ACE is associated with reduced sperm motility. Recently, we established an assay to detect testicular ACE activity in human spermatozoa. The purpose of this study was to determine if testicular ACE activity is related to sperm motility in human ejaculates. Semen samples were collected from 80 infertile patients. According to the semen characteristics, they were divided into four (WHO) categories. Enzyme activities of ACE in spermatozoa (testicular ACE) and seminal plasma (somatic ACE) were spectrophotometrically determined. Total testicular ACE activity in spermatozoa was measured by solubilization of spermatozoa with Triton X-100. Membrane testicular ACE activity was measured in a sperm : PBS suspension. Sperm concentration and sperm motility were 136.6 +/- 154.1 x 10(6)/mL and 58.6 +/- 23.4%, respectively (mean +/- SD). Enzyme activities of membrane testicular ACE, total testicular ACE and somatic ACE were 0.273 +/- 1.219 microU/10(6) spermatozoa, 0.35 +/- 1.34 microU/10(6) spermatozoa and 684.7 +/- 226.6 mU/mL, respectively. A negative correlation was observed between sperm motility and membrane testicular ACE activity (p < 0.05). Membrane testicular ACE activity in 44 normal semen samples was 0.04 +/- 0.02 microU/10(6) spermatozoa, whilst that in 36 abnormal semen samples was 0.24 +/- 0.42 microU/10(6) spermatozoa. There was a significant difference between these two groups (p < 0.01). Membrane testicular ACE in sperm samples from normozoospermic men was significantly lower than that from oligoasthenozoospermic men (p < 0.05). These findings suggest that testicular ACE is released from normal functional spermatozoa for them to have fertilizing ability.

A 20-year-old male presented fever, nausea and headache 1 week after eating uncooked liver. On admission, it was revealed he had suffered a closed head injury 3 months before without unconsciousness. On admission, computed tomography scan showed a left chronic subdural hematoma. Gd-DTPA magnetic resonance images revealed unusual enhancement of the capsule and linear enhancement of the subarachnoid space. The patient underwent burr hole irrigation and drainage. The culture of the hematoma content showed Campylobacter fetus. Therefore, the diagnose was infected subdural hematoma. A drainage operation and administration of antibiotics were effective. Our case suggests that enhanced magnetic resonance images are useful for diagnosis and follow-up of infected subdural hematoma.

We recently treated 2 patients with squamous cell carcinoma in the anal canal with bilateral inguinal nodal metastases using chemoradiotherapy. Chemotherapy (CT) consisted of 5-fluorouracil 700 mg/m2/day (continuous intravenously) on days 1-5 and cisplatin 50 mg/m2/day (continuous intravenously) on days 6-7. Chemotherapy was administered before the beginning of radiotherapy. In one patient, 2 cycles of CT were performed, and in the other patient 1 cycle only. The total radiation dose was 57.6 Gy to the primary lesion in each patient, and 53.6 Gy, 55.8 Gy to the nodal metastases, respectively. As a primary treatment response, CR was obtained in both patients. Acute grade 3-4 hematologic toxicities were observed in one patient. The patients have had 7 and 9 months survival without disease, and excellent function of the anal sphincter after treatment.

To evaluate the usefulness of chemoradiotherapy for oropharyngeal cancer, we retrospectively analyzed disease-free survival (DFS) and acute toxicities of the patients treated with this therapy. Between 1990 and 1998, 15 patients were treated with alternating chemoradiotherapy (CRT). Chemotherapy (CT) mainly consisted of 5-fluorouracil 700 mg/m2 (i.v.) on days 1-5 and nedaplatin 100-140 mg/m2 (i.v.) on day 6. Chemotherapy was administered before the beginning of radiotherapy. One cycle of this treatment consisted of CT and a subsequent 27 to 36 Gy of radiotherapy, as a general rule, two cycles were performed. Radiotherapy was delivered in single daily fractions of 1.8 to 2 Gy, to a total dose of 54 to 75 Gy for local lesions and 45 to 86.3 Gy for nodal metastases in the neck. As a historical control, 52 patients treated with curative radiotherapy between 1971 and 1990 were analyzed and compared with the CRT group in terms of DFS. The complete response rate with CRT was 100%. The three-year DFS were 87% and 38% with CRT and RT, respectively. There was a significant difference between the two groups (p = 0.0081). The most frequent and severe acute toxicity was mucositis, with grade 3-4 occurring in 47%. Acute hematologic toxicities were mild. Therefore, this CRT is considered to be an effective and tolerable treatment, and is expected to improve survival for oropharyngeal cancer patients.

To improve the treatment result for locally advanced head and neck carcinoma, the authors used a combination of radiotherapy with superselective continuous intraarterial therapy using carboplatin. The dose limiting toxicity (DLT), maximum tolerated dose (MTD), and treatment effectiveness were tested in Phase I and II protocols. PATIENTS AND METHODS. Thirty-five patients were entered into the study from August 1992 to May 1997. The target arteries were the lingual artery in 18 cases, facial artery in 5 cases, maxillary artery in 11 cases, and external carotid artery initially changing to lingual artery in 1 case. Escalating daily carboplatin doses were tested, starting from 10 mg/m(2) (total dose, 360 or 400 mg/m(2)) to 15 mg/m(2) (total dose, 405 or 450 mg/m(2)) and then 20 mg/m(2) (total dose, 460 or 500 mg/m(2)). Radiotherapy was administered using a 6-megavolt linear accelerator to a total dose of 50-60 grays. Interstitial radiotherapy boost also was used for carcinoma of the tongue.Excluding 3 patients who discontinued treatment, the treatment results of 32 patients were complete response in 21 cases, partial response in 10 cases, and no change in 1 case. Neutropenia was the DLT, and the MTD was 500 mg/m(2). The local control rate was 64%.Superselective continuous intraarterial carboplatin and concurrent radiation therapy can be delivered safely with good efficacy for locally advanced carcinomas of the tongue and base of the tongue. Surgical treatment of these diseases usually incurs severe functional loss. This current approach may be a breakthrough in these cancers.

Previous studies have shown that a monoclonal antibody, H-145, inhibits myotube formation of quail myoblasts transformed with a temperature-sensitive mutant of Rous sarcoma virus (QM-RSV cells) [Hyodo and Kim, 1994: Exp. Cell Res. 212:120-131]. The antigen recognized by H-145 (H-145 antigen), which is a glycoprotein with a molecular mass of about 116 kDa, is related to a step immediately before myoblast fusion. To determine the functional significance of H-145 antigen, we examined its dynamic state during myogenic differentiation of QM-RSV cells. H-145 antigen showed a unique and discrete distribution. In immature myotubes immediately after myoblast fusion, many ring-like structures of H-145 antigen appeared on the ventral surface of the cells, encircling the actin dots detected simultaneously by immunofluorescence and interference reflection microscopy. The core of the ring-like structures was filled with the termini of actin bundles, mainly formed by alpha-actin. Other cytoskeletal-associated proteins, such as vinculin and alpha-actinin, were also associated with these structures. The ring-like structures of H-145 antigen were observed only during a restricted period when myoblasts fused actively, suggesting their relationships to myotube formation and an early stage of myofibril formation. With maturation of the myotubes, most of the H-145 antigen became redistributed in linear arrays on the apical cell surface and was probably associated with the termini of actin bundles to organize myofibrils, suggesting that the antigen was also related to maturation of myotubes. Experiments using monoclonal antibodies against chick beta1 integrin showed that H-145 antigen is beta1 integrin or a very closely related derivation. Thus H-145 antigen (beta1 integrin) is possibly involved in both myoblast fusion and the myofibril organization in myotubes.

Intraluminal brachytherapy using a balloon applicator has been the treatment of choice for superficial esophageal carcinomas. During treatment, the applicator is made to expand to be cylindrical as determined from an AP radiograph. However, optimal expansion of the applicator is not usually confirmed by computed tomography (CT). Therefore, this study was conducted to assess the shape of the balloon applicator by CT. Ten patients with superficial esophageal carcinoma were treated with intraluminal brachytherapy using a balloon applicator. The applicators were expanded properly in all patients as viewed from the AP radiograph. In seven of 10 patients, optimal expansion of the applicator was observed on CT. However, in the remaining three patients, applicators were found to be distorted presumably not only by primary tumor and mediastinal lymph nodes but also by neighboring organs. These results indicate that, when treating superficial esophageal carcinoma using a balloon applicator, there may be risks of applicator distortion in some cases. Assessment by CT should be done to precisely confirm the shape of the applicator.

In order to investigate the relative efficacy and safety of zopiclone and zolpidem, we compared the effects of higher doses of zopiclone and zolpidem on the frequency of hippocampal theta activity and sleep structure with that of triazolam. Rats were divided into triazolam treatment group (1 mg/kg, 5 mg/kg), zopiclone treatment group (20 mg/kg, 100 mg/kg) and zolpidem treatment group (20 mg/kg, 100 mg/kg). Rats were injected intraperitoneally with these drugs or their vehicle. Polygraphic sleep recording and visual frequency analysis of the hippocampal EEG activity in REM sleep were carried out for 6 h after each injection. Zolpidem, unlike triazolam and zopiclone, had a much milder reducing-effect on the frequency of hippocampal theta activity and suppressing-effect on REM sleep. These results suggest that zolpidem may prove to be a safer hypnotic drug which has fewer or milder side effects than are benzodiazepine and cyclopyrrolone hypnotics.

A simple tapered directional coupler with a five-layered structure is employed for mode conversion between a single-order and higher-order modes. As a result, we confirmed that the first several modes in the tapered waveguide shift to single-order mode with high conversion efficiency by use of computer simulation, and observed the streak patterns of mode propagation experimentally.

Thirteen patients who underwent redo operation after surgical treatment of aortic aneurysm and dissection were presented. In 8 patients, redo operations were performed for aortic dissection following aortic valve replacement. A-C bypass, the Koster-Collins operation and replacement of thoracic aorta. In the other 5 patients, the reasons for redo operation were aortic root enlargement after replacement of ascending aorta and aortic valve replacement, pseudoaneurysm and aneurysmal dilatation around coronary button for the Bentall operation and recurrent aneurysm after patch aortoplasty and thoracoabdominal replacement using the Crawford's maneuver. To prevent these redo operation, adequate selection of surgical procedures and meticulous operative techniques should be required in primary operation.

For the purpose of the brain delivery of peptides, the structural specificity of adsorptive-mediated endocytosis at the blood-brain barrier was studied by measuring transport of a newly synthesized basic peptide 001-C8, H-MeTyr-Arg-MeArg-D-Leu-NH(CH2)aNH2, using primary cultured bovine brain capillary endothelial cells. The apparent uptake of [125I]001-C8 increased time-dependently and reached a steady-state at 60 min. The steady-state uptake of [125I]001-C8 was temperature and concentration dependent and was significantly decreased in the presence of dansylcadaverine, protamine or poly-L-lysine. Uptakes of peptides modified by 1,8-octanediamine, 1,5-pentanediamine, 1,2-ethanediamine or ethylamide and peptides with a free carboxyl terminal were significantly higher than, and similar to, that of [3H]PEG900, respectively. The half-saturation constants and the maximal uptake capacities of these peptides were in the ranges of 0.2 to 134 microM and 1.1 to 408 pmol/mg protein, respectively. These values were correlated with the basicity of the molecules. In conclusion, not the number of constituent amino acids of peptides, but rather the C-terminal structure and the basicity of the molecules are the most important determinants for the uptake by the adsorptive-mediated endocytosis system at the blood brain barrier.

PURPOSE: To evaluate the clinical importance of nerve root enhancement associated with lumbar disk herniation. METHODS: Thirty-two patients with lumbar disk herniation were examined with unenhanced and contrast-enhanced MR imaging. We investigated the relationship between nerve root enhancement and location of herniated disk in the epidural space, onset pattern of symptoms, subsequent treatment, and surgical findings. RESULTS: Ten of the 32 patients had nerve root enhancement, and all belonged to the group with abrupt and severe nerve root compression with no residual space for the root between the herniated disk and the pedicle in the lateral recess. Tight compression of the root without mobility was seen in the four patients with nerve root enhancement who were treated surgically. CONCLUSION: Nerve root enhancement may indicate the existence of abrupt and severe compression of the nerve root as well as the presence of severe adhesion of the herniated disk and the nerve root. This finding does not necessarily determine the type of subsequent treatment.

Ceramic samples of composition Ca0.9La0.1MnO3−δ having various oxygen contents were prepared by a quenching method under nitrogen atmosphere. As the 3 − δ value decreased from 2.97 to 2.79, the sample conductivity decreased from 102 to 10−1 S cm−1. The porous ceramic samples showed good properties as cathode materials in alkaline solution without using conductive material such as graphite, but the discharge capacity decreased with decreasing sample conductivity. The discharge termination is explained by a simple model considering dissipation of the conductive path (high conductivity core) present in the porous sintered ceramic.

A 7-year-old boy with partial anomalous pulmonary venous drainage to the high superior vena cava (SVC) underwent surgical repair by Williams procedure. Right upper pulmonary vein was drained to the left atrium via the SVC and the surgically enlarged sinus venosus type ASD. SVC was ligated and divided. SVC was then anastomosed to RA appendage pedicle directly. Autologous pericardium was patched anteriorly to create a new SVC pathway. The postoperative course was uneventful without arrhythmia and cardiac catheterization 1 month postoperation revealed no stenosis of the SVC and right upper pulmonary venous return.

The localization of Trimetaphosphatase (TMPase) activity during the acrosomal formation in the mouse testis was enzyme cytochemically investigated by the cerium-salt method. In addition to the lysosomes of the Sertoli cells and the spermatogenic cells in the seminiferous tubules, positive TMPase activity was detected in the Golgi complex and in the acrosomal vesicles of the spermatids, as well as in the acrosomes of both spermatids and spermatozoa. In the Golgi complex of the spermatids, TMPase activity was observed in the first one or two lamellae of the trans-face and in the small vesicles in the vicinity of the Golgi complex. TMPase positive reaction was also detected in the acrosomes of the spermatozoa in the lumina of both the seminiferous tubules and the epididymal duct. The localization of this enzyme activity was compared with that of acid phosphatase (ACPase), as detected by the cerium-based method, using beta-glycerophosphate as substrate: ACPase activity was completely absent from the Golgi complex, small vesicles, acrosomal vesicle and acrosome throughout the entire process of acrosomal formation. TMPase is thought to become one of the acrosomal components, and may be involved in the acrosomal reaction during fertilization.

A case of malignant transformation to a squamous cell carcinoma in a long-standing lumbar dermoid cyst is described. Progress was slow during 6 years. This type of transformation in a dermoid cyst is extremely uncommon and has never been recorded at this site.

Although Rheumatoid Arthritis (RA) is categorized in the systemic autoimmune diseases, specific autoantibodies in RA have been reported to be rare. We have investigated autoantibodies found in sera from patients with RA and examined their clinical significance. Immunoprecipitation techniques using 32P-labeled or 35S-labeled HeLa cell extracts and immunoblotting were utilized to detect autoantibodies in sera from 42 patients with RA and 58 patients with other connective tissue diseases as controls. Certain autoantibodies were detected in 33 of 42 patients (79%) with RA by any of the assay systems mentioned above. Anti-SSA/Ro, anti-SSB/La, anti-7-2RNP, and anti-Sm antibodies were found in 13 (29%), 3 (7%), 4 (10%), and 1 (2%) patients with RA, respectively. All 3 patients with anti-SSB/La and 9 with anti-SSA/Ro revealed Sjögren's syndrome besides RA. However, all 4 patients with anti-7-2RNP and one patient with anti-Sm showed no evidence of scleroderma nor SLE. Besides of these known autoantibodies, we have also detected 4 new antibodies which reacted with a 60kD protein in 15 (36%), 45kD in 10 (24%), 75kD in 8 (19%), 180kD in 4 patients (10%) with RA. These autoantibodies were not found in other connective tissue diseases except one of SLE for anti-60kD and one of dermatomyositis for anti-75kD, and therefore appeared to be specific for RA patients. Anti-45kD antibodies were associated with low prevalence of anti-nuclear antibodies, and anti-180kD antibodies were associated with lymphadenopathy and Sjögren's syndrome. Thus, it was demonstrated that patients with RA develop a variety of autoantibodies as well as those with other connective tissue diseases.

Transport processes in a mixed conductor (e.g. a UO2 pellet) are rigorously described by using an irreversible thermodynamic approach and a re-evaluation of the effect of thermoelectric power is carried out. The results indicate that the oxygen redistribution can be interpreted as an electrochemical mass transport phenomenon caused by thermoelectric power. The validity of this interpretation is confirmed using experimental results from other sources.

The cardiovascular effects of OPC-13340, a newly developed 1,4-dihydropyridine calcium channel blocker, were examined in several canine preparations. In conscious normotensive and DOCA-salt hypertensive dogs, OPC-13340, at doses of 10 to 30 micrograms/kg, i.v., and 0.3 to 3 mg/kg, p.o., exerted an hypotensive action in a dose-dependent manner. The hypotensive action of OPC-13340 was longer lasting and more potent than that of nicardipine and nifedipine. In conscious, normotensive instrumented dogs, OPC-13340, at doses of 1 and 3 mg/kg, p.o., dose-dependently decreased total peripheral resistance and mean blood pressure and increased heart rate, cardiac output and left ventricular contractility. In anesthetized open-chest dogs, OPC-13340, at doses of 1 to 30 micrograms/kg, i.v., increased coronary blood flow and decreased mean blood pressure, heart rate, coronary vascular resistance, arteriovenous oxygen difference and myocardial oxygen consumption. In contrast to OPC-13340, nicardipine did not change the myocardial oxygen consumption. From these results it was concluded that OPC-13340 lowered blood pressure and improved coronary circulation in dogs and that the duration of these actions was longer lasting than that of nifedipine and nicardipine. These actions of OPC-13340 may be useful in the treatment of hypertension and angina pectoris.

Intraoperative spinal cord monitorings using evoked spinal cord potentials (ESCP) have been performed in 19 patients with spinal cord tumors, including five intramedullary tumors and two arteriovenous malformations (AVM) since 1984. There were 10 men and 9 women between the ages of 22 and 73 years, with an average of 49 years. ESCP resulting from median or tibial and peroneal nerve and/or spinal cord stimulation were used for monitoring according to the spinal level of tumors.

Solid films of poly (γ-methyl l -glutamate) were prepared by casting solutions in chloroform, dichloromethane, and m -cresol. The mode and amplitude of thermal molecular fluctuations in the crystalline phase were studied by X-ray diffraction. All the films contain α-helical molecules and have hexagonal crystal structures, but differ from each other in their crystallinity and crystallite size. The calculated molecular fluctuation amplitudes also differ considerably. Below a threshold temperature in the range 140°–190°C (different for each sample), the segmental molecular motion is composed of translation along the chain axes coupled with rotation about the axes. At higher temperatures, the structure changes thermoreversibly into a modification, in which a screw-type motion along the α-helix axis is predominant.

The question is raised on the validity of the usual derivation of the Lipkin-Weisberger-Peshkin (LWP) difficulty. It is shown that the LWP difficulty can be derived legitimately in the framework of the Wu-Yang formalism. A non-abelian version of the LWP difficulty is presented in a Wu-Yang solution of the pure SU(2) Yang-Mills theory, showing a failure of the Jacobi identity at one point through the term − i 4π( r ·T)δ 3 (x) . A nonrelativistic treatment of the SU(2) doublet particle with spin 1 2 around this solution is given. Some remarks are made also on a possible LWP difficulty in the 't Hooft-Polyakov monopole.

Thermal oxidative deterioration and accumulation of peroxides (PO) in pan-frying oils were discussed. Through several experiments, it was observed that pan-frying oils were extremely deteriorated and showed very high peroxide values (POV ca. 230), especially in the case of thin-film heating. Panfrying oils were fractionated by silicic acid column chromatography, and POV and thermostability of PO in each fraction were investigated. The results indicate that PO, accumulated during thin-film heating, was not a specialized or thermostable PO. We conclude that the extensive formation of PO should show high POV during pan-frying. Anhaufung von Peroxiden im Fritierfett in der Pfanne Die thermisch-oxidative Zersetzung und die Anhaufung von Peroxiden im Fritierfett in der Pfanne werden diskutiert. In mehreren Versuchen wurde beobachtet, das solche Fritierfette stark verdorben werden und sehr hohe Peroxidzahlen (ca. 230) aufweisen, insbesondere nach Erhitzung als dunner Film. Fritierfette aus der Pfanne wurden durch Kieselgel-Saulenchromatographie, Peroxidzahl und thermische Bestandigkeit der Peroxide in jeder Fraktion untersucht. Die Ergebnisse zeigen, das die bei der Erhitzung als dunner Film gebildeten Peroxide thermisch nicht besonders bestandig sind. Daraus wird geschlossen, das die Bildung von Peroxiden beim Fritieren in der Pfanne moglichst hoch sein soll.

A spinor representation of bosons (spinorization method) is presented in 1+0 dimensions through Abel's integral transformation, and an action is written in the Dirac form up to surface terms. When applied to the supersymmetric N = 1 quantum mechanics a N = 1/2 SUSY of the action and the vacuum energy cancellation of quantum fluctuations become manifest in this representation.

In smooth muscle cells of the porcine coronary artery, phthalazinol (≦10−5 M) did not modify the membrane potential and the membrane resistance. At a concentration of 10−4 M or higher, it hyperpolarized the membrane, reduced the membrane resistance and enhanced the rectifying property of the membrane. At the concentration of 10−5 M, phthalazinol raised the threshold for the induction of a contraction and suppressed nonselectively the amplitude of the contraction evoked by application of high [K]0, acetylcholine or electrical depolarization of the membrane. Phthalazinol (10−5–10−4 M) did not modify the membrane properties of smooth muscle cells from the guinea-pig vas deferens. However, it suppressed the amplitude of the excitatory junction potentials and the facilitation phenomenon produced by repetitive stimulation at various rates. The action potential recorded from the adrenergic nerves was not affected in the presence of phthalazinol (10−5 and 10−4 M). The mean amplitude of the miniature excitatory junction potentials (m.e.j.p.s.) was not affected by treatment with phthalazinol (10−5–10−4 M), but the rate of which of m.e.j.p.s. appeared was reduced by phthalazinol (>5×10−5 M). These results indicate that the vasodilator property of phthalazinol may result from a suppression of Ca-mobilization in both the smooth muscle cells and the adrenergic nerve terminals. The former affects the mechanical response directly and the latter leads to an inhibition of noradrenaline release.

The half-order differential operators are used to represent bosonic fields in spinor forms (spinorization) and are applied to supersymmetric (1+1)-dimensional potential model with solitons. A manifestN=1/2 SUSY of bosonic and fermionic fluctuations is obtained. The Witten-Olive conjecture on the saturation of the Bogomonly bounds is reconfirmed in the one-loop quantum level.

We present an exact rotating Schwinger dyon solution for which the space-time metric takes the Kerr-Newman form. Our solution is characterized by four physical parameters: massM, angular momentumS, electric chargeQ and magnetic chargeΦ, and reduces to the rotating Dirac monopole in the caseQ=0.

Various reports have been published on corntrol systems for slab reheating furnaces centering on the theme of energy savings. But, due to the fact that the process description is largely non-linear and hounded with many restrictive conditions no system was formularized in the past that would simultaneously satisfy two targets, minimum deviation in the extracted slab temprature and maximum reheating efficiency. The present control system, however, is a system that satisfies both targets simultaneously. Although it makes us p of experimental laws in part, it provides all the internal characteristics and control laws of the process in formularizerd forms. The system is composed of an observer and predictor to ensure sub-optimization. As for the control method, it is based on feed forward control and is characterized by the fact that control of the fuel distribution to each zone is always directed toward securing Maximum efficiency .

The continuous esterification of acetic acid in an excess ethanol with sulfuric acid catalyst was studied, using a packed tower. The main reaction tower, 157.8cm in height and 3.79cm in diameter, was packed with Raschig rings (5.78×8.10mm). The feed of alcohol, vaporized through the vaporizer, was led to the bottom of the tower, and the feed of acetic acid and catalyst sulfuric acid was mixed with the reflux and led to the top of the tower in a liquid form. When the reaction was completed, samples were taken and examined so as to determine the composition.The analysis has been made on the following assumptions:(1) The reaction is homogeneous in the liquid phase.(2) The ester formed is rapidly removed and reverse reaction is negligible. In an excess alcohol, the reaction is that of first order in respect to acetic acid concentration.(3) There is a certain proportional relationship between liquid composition and its equilibrium gas composition.The general relations derived on these assumptions are expressed by Eqs. (3), (4), (9) and (10). When the rate of mass transfer is very small compared with the reaction rate, said relations can be simplified in the form of Eq. (16). From the experimental results, the calculated reaction constant is found to be proportional to the sulfuric acid catalyst concentration, as shown in Fig. 4.

Model tests were carried out to study the deformation characteristics of abutments during liquefaction. In the tests, fine sand was used to model the saturated ground and the embankment. The model constructed inside the box was subjected to sinusoidal vibration with the help of a shaking table. The variation of pore water pressure, the earth pressure and the acceleration were measured with different kinds of transducers and the deformed pattern of the model was observed through a video camera. In addition to the comparison and estimation of the earthquake resistance of various abutments, the effect of the sheet pile method with respect to the stability of abutments constructed on embankments was also investigated.

Les deux complexes etudies par diffraction RX cristallisent dans le systeme monoclinique. Coordination bypyramidale rhomboedrique autour de l'atome metallique dans les deux cas. Spectrometrie RMN du complexe pour R=H, R'=Ph. Calculs d'orbitale moleculaire selon la methode d'Huckel generalisee pour Mo(HS) 2 (HNC) 2 (HC≡HC) dans neuf variations geometriques

The present investigation was undertaken to develop a standard method of recording the bone measurements of the normal hand for use in comparative studies of genetic abnormalities of the skeletal system affecting the hand. The data for this study are obtained from the radiographs of the hands of normal 461 males and 565 females aged from 20 to 84 years. Measurements of length and width of all the phalanges and metacarpals are recorded. The phalangeal index and metacarpal index of each bone are obtained by dividing the length by the width. Frequencies of brachymesophalangy of the little finger and brachytelephalangy of the thumb are investigated. There are no significant differences between the bone of the right and left hand related to hand dominance. The radiographs of the hands of mother and son with the Marfan syndrome were compared with normal one. Metacarpal index and phalangeal index are useful for diagnosis of the Marfan syndrome.