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51. Sex-steroid hormones and risk of postmenopausal estrogen receptor-positive breast cancer: a case-cohort analysis

Author

Albers, Frances EM, primary, Lou, Makayla WC, additional, Dashti, S Ghazaleh, additional, Swain, Christopher TV, additional, Rinaldi, Sabina, additional, Viallon, Vivian, additional, Karahalios, Amalia, additional, Brown, Kristy A, additional, Gunter, Marc J, additional, Milne, Roger L, additional, English, Dallas R, additional, and Lynch, Brigid M, additional

Published
2023
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54. Sedentary Behaviour and Cancer

Author

Lynch, Brigid M., Mahmood, Shahid, Boyle, Terry, Ahrens, Wolfgang, Series editor, Pigeot, Iris, Series editor, Leitzmann, Michael F., editor, Jochem, Carmen, editor, and Schmid, Daniela, editor

Published
2018
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55. Intratumoral presence of the genotoxic gut bacteria pks+E. coli, Enterotoxigenic Bacteroides fragilis, and Fusobacterium nucleatum and their association with clinicopathological and molecular features of colorectal cancer.

Author

Joo, Jihoon E., Chu, Yen Lin, Georgeson, Peter, Walker, Romy, Mahmood, Khalid, Clendenning, Mark, Meyers, Aaron L., Como, Julia, Joseland, Sharelle, Preston, Susan G., Diepenhorst, Natalie, Toner, Julie, Ingle, Danielle J., Sherry, Norelle L., Metz, Andrew, Lynch, Brigid M., Milne, Roger L., Southey, Melissa C., Hopper, John L., and Win, Aung Ko

Abstract

Background: This study aimed to investigate clinicopathological and molecular tumour features associated with intratumoral pks+Escherichia coli (pks+E.coli+), pks+E.coli- (non-E.coli bacteria harbouring the pks island), Enterotoxigenic Bacteroides fragilis (ETBF) and Fusobacterium nucleatum (F. nucleatum). Methods: We screened 1697 tumour-derived DNA samples from the Australasian Colorectal Cancer Family Registry, Melbourne Collaborative Cohort Study and the ANGELS study using targeted PCR. Results: Pks+E.coli+ was associated with male sex (P < 0.01) and APC:c.835-8 A > G somatic mutation (P = 0.03). The association between pks+E.coli+ and APC:c.835-8 A > G was specific to early-onset CRCs (diagnosed<45years, P = 0.02). The APC:c.835-A > G was not associated with pks+E.coli- (P = 0.36). F. nucleatum was associated with DNA mismatch repair deficiency (MMRd), BRAF:c.1799T>A p.V600E mutation, CpG island methylator phenotype, proximal tumour location, and high levels of tumour infiltrating lymphocytes (Ps < 0.01). In the stratified analysis by MMRd subgroups, F. nucleatum was associated with Lynch syndrome, MLH1 methylated and double MMR somatic mutated MMRd subgroups (Ps < 0.01). Conclusion: Intratumoral pks+E.coli+ but not pks+E.coli- are associated with CRCs harbouring the APC:c.835-8 A > G somatic mutation, suggesting that this mutation is specifically related to DNA damage from colibactin-producing E.coli exposures. F. nucleatum was associated with both hereditary and sporadic MMRd subtypes, suggesting the MMRd tumour microenvironment is important for F. nucleatum colonisation irrespective of its cause. [ABSTRACT FROM AUTHOR]

Published
2024
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56. Adherence to 2018 WCRF/AICR Cancer Prevention Recommendations and Risk of Cancer: The Melbourne Collaborative Cohort Study.

Author

Yang Peng, Bassett, Julie K., Hodge, Allison M., Melaku, Yohannes Adama, Afshar, Nina, Hopper, John L., MacInnis, Robert J., Lynch, Brigid M., Smith-Warner, Stephanie A., Giles, Graham G., Milne, Roger L., and Jayasekara, Harindra

Abstract

Background: We examined associations between adherence to adaptations of the 2018 World Cancer Research Fund/American Institute for Cancer Research (WCRF/AICR) cancer prevention recommendations and total, exposure-related and site-specific cancer risk. Methods: A total of 20,001 participants ages 40 to 69 years at enrollment into the Melbourne Collaborative Cohort Study in 1990 to 1994, who had diet, body size, and lifestyle reassessed in 2003 to 2007 ("baseline"), were followed-up through June 2021. We constructed diet and standardized lifestyle scores based on core WCRF/AICR recommendations on diet, alcohol intake, body size and physical activity, and additional scores incorporating weight change, sedentary behavior, and smoking. Associations with cancer risk were estimated using Cox regression, adjusting for confounders. Results: During follow-up (mean = 16 years), 4,710 incident cancers were diagnosed. For highest quintile ("most adherent") of the standardized lifestyle score, compared with lowest ("least adherent"), a HR of 0.82 [95% confidence interval (CI): 0.74-0.92] was observed for total cancer. This association was stronger with smoking included in the score (HR = 0.74; 95% CI: 0.67-0.81). A higher score was associated with lower breast and prostate cancer risk for the standardized score, and with lung, stomach, rectal, and pancreatic cancer risk when the score included smoking. Our analyses identified alcohol use, waist circumference and smoking as key drivers of associations with total cancer risk. Conclusions: Adherence to WCRF/AICR cancer prevention recommendations is associated with lower cancer risk. [ABSTRACT FROM AUTHOR]

Published
2024
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57. Sustained Hypothetical Interventions on Midlife Alcohol Consumption in Relation to All-Cause and Cancer Mortality: The Australian Longitudinal Study on Women's Health.

Author

Yang, Yi, Hodge, Allison M, Lynch, Brigid M, Dugué, Pierre-Antoine, Williamson, Elizabeth J, Jayasekara, Harindra, Mishra, Gita, and English, Dallas R

Subjects
SCIENTIFIC observation, ALCOHOL drinking, TUMORS, WOMEN'S health, LONGITUDINAL method
Abstract

No randomized controlled trial has evaluated the effect of long-term alcohol interventions on mortality. Results reported in existing observational studies may be subject to selection bias and time-varying confounding. Using data from the Australian Longitudinal Study on Women's Health 1946–1951 birth cohort, collected regularly from 1996–2016, we estimated all-cause and cancer mortality had women been assigned various alcohol interventions (in categories ranging from 0 to >30 g/day ethanol, or reduced to ≤20 g/day if higher) at baseline, and had they maintained these levels of consumption. The cumulative risks for all-cause and cancer mortality were 5.6% (10,118 women followed for 20 years) and 2.9% (18 years), respectively. For all-cause and cancer mortality, baseline ethanol up to 30 g/day showed lower risk and >30 g/day showed higher risk relative to abstention. Had women sustainedly followed the interventions, a similar relationship was observed for all-cause mortality. However, the negative association observed for intakes ≤30 g/day and positive association for intakes >30 g/day was not evident for cancer mortality. Our findings suggest that all-cause mortality could have been lower than observed if this cohort of women had consumed some alcohol (no more than 30 g/day) rather than no consumption, but cancer mortality might not. [ABSTRACT FROM AUTHOR]

Published
2024
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58. Leisure time television watching, computer use and risks of breast, colorectal and prostate cancer: A Mendelian randomisation analysis.

Author

Papadimitriou, Nikos, Kazmi, Nabila, Dimou, Niki, Tsilidis, Konstantinos K., Martin, Richard M., Lewis, Sarah J., Lynch, Brigid M., Hoffmeister, Michael, Sun-Seog Kweon, Li Li, Milne, Roger L., Sakoda, Lori C., Schoen, Robert E., Phipps, Amanda I., Figueiredo, Jane C., Peters, Ulrike, Dixon-Suen, Suzanne C., Gunter, Marc J., and Murphy, Neil

Subjects
COLORECTAL cancer, PROSTATE cancer, TELEVISION viewing, LEISURE, GENOME-wide association studies
Abstract

Background: Sedentary behaviours have been associated with increased risks of some common cancers in epidemiological studies; however, it is unclear if these associations are causal. Methods: We used univariable and multivariable two-sample Mendelian randomisation (MR) to examine potential causal relationships between sedentary behaviours and risks of breast, colorectal and prostate cancer. Genetic variants associated with self-reported leisure television watching and computer use were identified from a recent genome-wide association study (GWAS). Data related to cancer risk were obtained from cancer GWAS consortia. A series of sensitivity analyses were applied to examine the robustness of the results to the presence of confounding. Results: A 1-standard deviation (SD: 1.5h/day) increment in hours of television watching increased risk of breast cancer (OR per 1-SD: 1.15, 95% confidence interval [CI]: 1.05–1.26) and colorectal cancer (OR per 1-SD: 1.32, 95% CI: 1.16– 1.49) while there was little evidence of an association for prostate cancer risk (OR per 1-SD: 0.94, 95% CI: 0.84–1.06). After adjusting for years of education, the effect estimates for television watching were attenuated (breast cancer, OR per 1-SD: 1.08, 95% CI: 0.92–1.27; colorectal cancer, OR per 1-SD: 1.08, 95% CI: 0.90–1.31). Post hoc analyses showed that years of education might have a possible confounding and mediating role in the association between television watching with breast and colorectal cancer. Consistent results were observed for each cancer site according to sex (colorectal cancer), anatomical subsites and cancer subtypes. There was little evidence of associations between genetically predicted computer use and cancer risk. Conclusions: Our univariable analysis identified some positive associations between hours of television watching and risks of breast and colorectal cancer. However, further adjustment for additional lifestyle factors especially years of education attenuated these results. Future studies using objective measures of exposure can provide new insights into the possible role of sedentary behaviour in cancer development. [ABSTRACT FROM AUTHOR]

Published
2024
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59. A Multifaceted Activity Program Preserves VO2peak In Adults Undergoing Allogeneic Stem Cell Transplantation For Hematological Cancer

Author

Dillon, Hayley T., primary, Saner, Nicholas J., additional, Ilsley, Tegan, additional, Kliman, David, additional, Spencer, Andrew, additional, Avery, Sharon, additional, Dunstan, David W., additional, Daly, Robin M., additional, Fraser, Steve F., additional, Owen, Neville, additional, Lynch, Brigid M., additional, Kingwell, Bronwyn A., additional, La Gerche, Andre, additional, and Howden, Erin J., additional

Published
2023
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61. Data from A Genetic Locus within the FMN1/GREM1 Gene Region Interacts with Body Mass Index in Colorectal Cancer Risk

Author

Aglago, Elom K., primary, Kim, Andre, primary, Lin, Yi, primary, Qu, Conghui, primary, Evangelou, Marina, primary, Ren, Yu, primary, Morrison, John, primary, Albanes, Demetrius, primary, Arndt, Volker, primary, Barry, Elizabeth L., primary, Baurley, James W., primary, Berndt, Sonja I., primary, Bien, Stephanie A., primary, Bishop, D. Timothy, primary, Bouras, Emmanouil, primary, Brenner, Hermann, primary, Buchanan, Daniel D., primary, Budiarto, Arif, primary, Carreras-Torres, Robert, primary, Casey, Graham, primary, Cenggoro, Tjeng Wawan, primary, Chan, Andrew T., primary, Chang-Claude, Jenny, primary, Chen, Xuechen, primary, Conti, David V., primary, Devall, Matthew, primary, Diez-Obrero, Virginia, primary, Dimou, Niki, primary, Drew, David, primary, Figueiredo, Jane C., primary, Gallinger, Steven, primary, Giles, Graham G., primary, Gruber, Stephen B., primary, Gsur, Andrea, primary, Gunter, Marc J., primary, Hampel, Heather, primary, Harlid, Sophia, primary, Hidaka, Akihisa, primary, Harrison, Tabitha A., primary, Hoffmeister, Michael, primary, Huyghe, Jeroen R., primary, Jenkins, Mark A., primary, Jordahl, Kristina, primary, Joshi, Amit D., primary, Kawaguchi, Eric S., primary, Keku, Temitope O., primary, Kundaje, Anshul, primary, Larsson, Susanna C., primary, Marchand, Loic Le, primary, Lewinger, Juan Pablo, primary, Li, Li, primary, Lynch, Brigid M., primary, Mahesworo, Bharuno, primary, Mandic, Marko, primary, Obón-Santacana, Mireia, primary, Moreno, Victor, primary, Murphy, Neil, primary, Nan, Hongmei, primary, Nassir, Rami, primary, Newcomb, Polly A., primary, Ogino, Shuji, primary, Ose, Jennifer, primary, Pai, Rish K., primary, Palmer, Julie R., primary, Papadimitriou, Nikos, primary, Pardamean, Bens, primary, Peoples, Anita R., primary, Platz, Elizabeth A., primary, Potter, John D., primary, Prentice, Ross L., primary, Rennert, Gad, primary, Ruiz-Narvaez, Edward, primary, Sakoda, Lori C., primary, Scacheri, Peter C., primary, Schmit, Stephanie L., primary, Schoen, Robert E., primary, Shcherbina, Anna, primary, Slattery, Martha L., primary, Stern, Mariana C., primary, Su, Yu-Ru, primary, Tangen, Catherine M., primary, Thibodeau, Stephen N., primary, Thomas, Duncan C., primary, Tian, Yu, primary, Ulrich, Cornelia M., primary, van Duijnhoven, Franzel JB, primary, Van Guelpen, Bethany, primary, Visvanathan, Kala, primary, Vodicka, Pavel, primary, Wang, Jun, primary, White, Emily, primary, Wolk, Alicja, primary, Woods, Michael O., primary, Wu, Anna H., primary, Zemlianskaia, Natalia, primary, Hsu, Li, primary, Gauderman, W. James, primary, Peters, Ulrike, primary, Tsilidis, Konstantinos K., primary, and Campbell, Peter T., primary

Published
2023
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62. Supplementary Data from A Genetic Locus within the FMN1/GREM1 Gene Region Interacts with Body Mass Index in Colorectal Cancer Risk

Author

Aglago, Elom K., primary, Kim, Andre, primary, Lin, Yi, primary, Qu, Conghui, primary, Evangelou, Marina, primary, Ren, Yu, primary, Morrison, John, primary, Albanes, Demetrius, primary, Arndt, Volker, primary, Barry, Elizabeth L., primary, Baurley, James W., primary, Berndt, Sonja I., primary, Bien, Stephanie A., primary, Bishop, D. Timothy, primary, Bouras, Emmanouil, primary, Brenner, Hermann, primary, Buchanan, Daniel D., primary, Budiarto, Arif, primary, Carreras-Torres, Robert, primary, Casey, Graham, primary, Cenggoro, Tjeng Wawan, primary, Chan, Andrew T., primary, Chang-Claude, Jenny, primary, Chen, Xuechen, primary, Conti, David V., primary, Devall, Matthew, primary, Diez-Obrero, Virginia, primary, Dimou, Niki, primary, Drew, David, primary, Figueiredo, Jane C., primary, Gallinger, Steven, primary, Giles, Graham G., primary, Gruber, Stephen B., primary, Gsur, Andrea, primary, Gunter, Marc J., primary, Hampel, Heather, primary, Harlid, Sophia, primary, Hidaka, Akihisa, primary, Harrison, Tabitha A., primary, Hoffmeister, Michael, primary, Huyghe, Jeroen R., primary, Jenkins, Mark A., primary, Jordahl, Kristina, primary, Joshi, Amit D., primary, Kawaguchi, Eric S., primary, Keku, Temitope O., primary, Kundaje, Anshul, primary, Larsson, Susanna C., primary, Marchand, Loic Le, primary, Lewinger, Juan Pablo, primary, Li, Li, primary, Lynch, Brigid M., primary, Mahesworo, Bharuno, primary, Mandic, Marko, primary, Obón-Santacana, Mireia, primary, Moreno, Victor, primary, Murphy, Neil, primary, Nan, Hongmei, primary, Nassir, Rami, primary, Newcomb, Polly A., primary, Ogino, Shuji, primary, Ose, Jennifer, primary, Pai, Rish K., primary, Palmer, Julie R., primary, Papadimitriou, Nikos, primary, Pardamean, Bens, primary, Peoples, Anita R., primary, Platz, Elizabeth A., primary, Potter, John D., primary, Prentice, Ross L., primary, Rennert, Gad, primary, Ruiz-Narvaez, Edward, primary, Sakoda, Lori C., primary, Scacheri, Peter C., primary, Schmit, Stephanie L., primary, Schoen, Robert E., primary, Shcherbina, Anna, primary, Slattery, Martha L., primary, Stern, Mariana C., primary, Su, Yu-Ru, primary, Tangen, Catherine M., primary, Thibodeau, Stephen N., primary, Thomas, Duncan C., primary, Tian, Yu, primary, Ulrich, Cornelia M., primary, van Duijnhoven, Franzel JB, primary, Van Guelpen, Bethany, primary, Visvanathan, Kala, primary, Vodicka, Pavel, primary, Wang, Jun, primary, White, Emily, primary, Wolk, Alicja, primary, Woods, Michael O., primary, Wu, Anna H., primary, Zemlianskaia, Natalia, primary, Hsu, Li, primary, Gauderman, W. James, primary, Peters, Ulrike, primary, Tsilidis, Konstantinos K., primary, and Campbell, Peter T., primary

Published
2023
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63. Table 2 from A Genetic Locus within the FMN1/GREM1 Gene Region Interacts with Body Mass Index in Colorectal Cancer Risk

Author

Aglago, Elom K., primary, Kim, Andre, primary, Lin, Yi, primary, Qu, Conghui, primary, Evangelou, Marina, primary, Ren, Yu, primary, Morrison, John, primary, Albanes, Demetrius, primary, Arndt, Volker, primary, Barry, Elizabeth L., primary, Baurley, James W., primary, Berndt, Sonja I., primary, Bien, Stephanie A., primary, Bishop, D. Timothy, primary, Bouras, Emmanouil, primary, Brenner, Hermann, primary, Buchanan, Daniel D., primary, Budiarto, Arif, primary, Carreras-Torres, Robert, primary, Casey, Graham, primary, Cenggoro, Tjeng Wawan, primary, Chan, Andrew T., primary, Chang-Claude, Jenny, primary, Chen, Xuechen, primary, Conti, David V., primary, Devall, Matthew, primary, Diez-Obrero, Virginia, primary, Dimou, Niki, primary, Drew, David, primary, Figueiredo, Jane C., primary, Gallinger, Steven, primary, Giles, Graham G., primary, Gruber, Stephen B., primary, Gsur, Andrea, primary, Gunter, Marc J., primary, Hampel, Heather, primary, Harlid, Sophia, primary, Hidaka, Akihisa, primary, Harrison, Tabitha A., primary, Hoffmeister, Michael, primary, Huyghe, Jeroen R., primary, Jenkins, Mark A., primary, Jordahl, Kristina, primary, Joshi, Amit D., primary, Kawaguchi, Eric S., primary, Keku, Temitope O., primary, Kundaje, Anshul, primary, Larsson, Susanna C., primary, Marchand, Loic Le, primary, Lewinger, Juan Pablo, primary, Li, Li, primary, Lynch, Brigid M., primary, Mahesworo, Bharuno, primary, Mandic, Marko, primary, Obón-Santacana, Mireia, primary, Moreno, Victor, primary, Murphy, Neil, primary, Nan, Hongmei, primary, Nassir, Rami, primary, Newcomb, Polly A., primary, Ogino, Shuji, primary, Ose, Jennifer, primary, Pai, Rish K., primary, Palmer, Julie R., primary, Papadimitriou, Nikos, primary, Pardamean, Bens, primary, Peoples, Anita R., primary, Platz, Elizabeth A., primary, Potter, John D., primary, Prentice, Ross L., primary, Rennert, Gad, primary, Ruiz-Narvaez, Edward, primary, Sakoda, Lori C., primary, Scacheri, Peter C., primary, Schmit, Stephanie L., primary, Schoen, Robert E., primary, Shcherbina, Anna, primary, Slattery, Martha L., primary, Stern, Mariana C., primary, Su, Yu-Ru, primary, Tangen, Catherine M., primary, Thibodeau, Stephen N., primary, Thomas, Duncan C., primary, Tian, Yu, primary, Ulrich, Cornelia M., primary, van Duijnhoven, Franzel JB, primary, Van Guelpen, Bethany, primary, Visvanathan, Kala, primary, Vodicka, Pavel, primary, Wang, Jun, primary, White, Emily, primary, Wolk, Alicja, primary, Woods, Michael O., primary, Wu, Anna H., primary, Zemlianskaia, Natalia, primary, Hsu, Li, primary, Gauderman, W. James, primary, Peters, Ulrike, primary, Tsilidis, Konstantinos K., primary, and Campbell, Peter T., primary

Published
2023
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64. Table 1 from A Genetic Locus within the FMN1/GREM1 Gene Region Interacts with Body Mass Index in Colorectal Cancer Risk

Author

Aglago, Elom K., primary, Kim, Andre, primary, Lin, Yi, primary, Qu, Conghui, primary, Evangelou, Marina, primary, Ren, Yu, primary, Morrison, John, primary, Albanes, Demetrius, primary, Arndt, Volker, primary, Barry, Elizabeth L., primary, Baurley, James W., primary, Berndt, Sonja I., primary, Bien, Stephanie A., primary, Bishop, D. Timothy, primary, Bouras, Emmanouil, primary, Brenner, Hermann, primary, Buchanan, Daniel D., primary, Budiarto, Arif, primary, Carreras-Torres, Robert, primary, Casey, Graham, primary, Cenggoro, Tjeng Wawan, primary, Chan, Andrew T., primary, Chang-Claude, Jenny, primary, Chen, Xuechen, primary, Conti, David V., primary, Devall, Matthew, primary, Diez-Obrero, Virginia, primary, Dimou, Niki, primary, Drew, David, primary, Figueiredo, Jane C., primary, Gallinger, Steven, primary, Giles, Graham G., primary, Gruber, Stephen B., primary, Gsur, Andrea, primary, Gunter, Marc J., primary, Hampel, Heather, primary, Harlid, Sophia, primary, Hidaka, Akihisa, primary, Harrison, Tabitha A., primary, Hoffmeister, Michael, primary, Huyghe, Jeroen R., primary, Jenkins, Mark A., primary, Jordahl, Kristina, primary, Joshi, Amit D., primary, Kawaguchi, Eric S., primary, Keku, Temitope O., primary, Kundaje, Anshul, primary, Larsson, Susanna C., primary, Marchand, Loic Le, primary, Lewinger, Juan Pablo, primary, Li, Li, primary, Lynch, Brigid M., primary, Mahesworo, Bharuno, primary, Mandic, Marko, primary, Obón-Santacana, Mireia, primary, Moreno, Victor, primary, Murphy, Neil, primary, Nan, Hongmei, primary, Nassir, Rami, primary, Newcomb, Polly A., primary, Ogino, Shuji, primary, Ose, Jennifer, primary, Pai, Rish K., primary, Palmer, Julie R., primary, Papadimitriou, Nikos, primary, Pardamean, Bens, primary, Peoples, Anita R., primary, Platz, Elizabeth A., primary, Potter, John D., primary, Prentice, Ross L., primary, Rennert, Gad, primary, Ruiz-Narvaez, Edward, primary, Sakoda, Lori C., primary, Scacheri, Peter C., primary, Schmit, Stephanie L., primary, Schoen, Robert E., primary, Shcherbina, Anna, primary, Slattery, Martha L., primary, Stern, Mariana C., primary, Su, Yu-Ru, primary, Tangen, Catherine M., primary, Thibodeau, Stephen N., primary, Thomas, Duncan C., primary, Tian, Yu, primary, Ulrich, Cornelia M., primary, van Duijnhoven, Franzel JB, primary, Van Guelpen, Bethany, primary, Visvanathan, Kala, primary, Vodicka, Pavel, primary, Wang, Jun, primary, White, Emily, primary, Wolk, Alicja, primary, Woods, Michael O., primary, Wu, Anna H., primary, Zemlianskaia, Natalia, primary, Hsu, Li, primary, Gauderman, W. James, primary, Peters, Ulrike, primary, Tsilidis, Konstantinos K., primary, and Campbell, Peter T., primary

Published
2023
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65. Physical activity, sedentary time and breast cancer risk: a Mendelian randomisation study

Author

Dixon-Suen, Suzanne C, Lewis, Sarah J, Martin, Richard M, English, Dallas R, Boyle, Terry, Giles, Graham G, Michailidou, Kyriaki, Bolla, Manjeet K, Wang, Qin, Dennis, Joe, Lush, Michael, Investigators, Abctb, Ahearn, Thomas U, Ambrosone, Christine B, Andrulis, Irene L, Anton-Culver, Hoda, Arndt, Volker, Aronson, Kristan J, Augustinsson, Annelie, Auvinen, Päivi, Beane Freeman, Laura E, Becher, Heiko, Beckmann, Matthias W, Behrens, Sabine, Bermisheva, Marina, Blomqvist, Carl, Bogdanova, Natalia V, Bojesen, Stig E, Bonanni, Bernardo, Brenner, Hermann, Brüning, Thomas, Buys, Saundra S, Camp, Nicola J, Campa, Daniele, Canzian, Federico, Castelao, Jose E, Cessna, Melissa H, Chang-Claude, Jenny, Chanock, Stephen J, Clarke, Christine L, Conroy, Don M, Couch, Fergus J, Cox, Angela, Cross, Simon S, Czene, Kamila, Daly, Mary B, Devilee, Peter, Dörk, Thilo, Dwek, Miriam, Eccles, Diana M, Eliassen, A Heather, Engel, Christoph, Eriksson, Mikael, Evans, D Gareth, Fasching, Peter A, Fletcher, Olivia, Flyger, Henrik, Fritschi, Lin, Gabrielson, Marike, Gago-Dominguez, Manuela, García-Closas, Montserrat, García-Sáenz, José A, Goldberg, Mark S, Guénel, Pascal, Gündert, Melanie, Hahnen, Eric, Haiman, Christopher A, Häberle, Lothar, Håkansson, Niclas, Hall, Per, Hamann, Ute, Hart, Steven N, Harvie, Michelle, Hillemanns, Peter, Hollestelle, Antoinette, Hooning, Maartje J, Hoppe, Reiner, Hopper, John, Howell, Anthony, Hunter, David J, Jakubowska, Anna, Janni, Wolfgang, John, Esther M, Jung, Audrey, Kaaks, Rudolf, Keeman, Renske, Kitahara, Cari M, Koutros, Stella, Kraft, Peter, Kristensen, Vessela N, Kubelka-Sabit, Katerina, Kurian, Allison W, Lacey, James V, Lambrechts, Diether, Le Marchand, Loic, Lindblom, Annika, Loibl, Sibylle, Lubiński, Jan, Mannermaa, Arto, Manoochehri, Mehdi, Margolin, Sara, Martinez, Maria Elena, Mavroudis, Dimitrios, Menon, Usha, Mulligan, Anna Marie, Murphy, Rachel A, Collaborators, Nbcs, Nevanlinna, Heli, Nevelsteen, Ines, Newman, William G, Offit, Kenneth, Olshan, Andrew F, Olsson, Håkan, Orr, Nick, Patel, Alpa, Peto, Julian, Plaseska-Karanfilska, Dijana, Presneau, Nadege, Rack, Brigitte, Radice, Paolo, Rees-Punia, Erika, Rennert, Gad, Rennert, Hedy S, Romero, Atocha, Saloustros, Emmanouil, Sandler, Dale P, Schmidt, Marjanka K, Schmutzler, Rita K, Schwentner, Lukas, Scott, Christopher, Shah, Mitul, Shu, Xiao-Ou, Simard, Jacques, Southey, Melissa C, Stone, Jennifer, Surowy, Harald, Swerdlow, Anthony J, Tamimi, Rulla M, Tapper, William J, Taylor, Jack A, Terry, Mary Beth, Tollenaar, Rob AEM, Troester, Melissa A, Truong, Thérèse, Untch, Michael, Vachon, Celine M, Joseph, Vijai, Wappenschmidt, Barbara, Weinberg, Clarice R, Wolk, Alicja, Yannoukakos, Drakoulis, Zheng, Wei, Ziogas, Argyrios, Dunning, Alison M, Pharoah, Paul DP, Easton, Douglas F, Milne, Roger L, Lynch, Brigid M, Breast Cancer Association Consortium, Law and Economics, Medical Oncology, Dixon-Suen, Suzanne C [0000-0003-3714-8386], Boyle, Terry [0000-0001-6741-330X], Romero, Atocha [0000-0002-1634-7397], Lynch, Brigid M [0000-0001-8060-547X], Apollo - University of Cambridge Repository, Dixon-Suen, Suzanne C, Lewis, Sarah J, Martin, Richard M, English, Dallas R, Boyle, Terry, Lynch, Brigid M, ABCTB Investigators, NBCS Collaborators, and Breast Canc Assoc Consortium

Subjects
Breast Neoplasms, Physical Therapy, Sports Therapy and Rehabilitation, Polymorphism, Single Nucleotide, Article, Basic medicine, breast cancer risk, SDG 3 - Good Health and Well-being, Risk Factors, sedentary behaviour, Genetics, Humans, Orthopedics and Sports Medicine, Breast, causal inference, Exercise, Manchester Cancer Research Centre, Physical activity, genetic variants, Breast Neoplasms/epidemiology, ResearchInstitutes_Networks_Beacons/mcrc, General Medicine, Mendelian Randomization Analysis, FOS: Biological sciences, Clinical medicine, instruments, physical inactivity, Sedentary Behaviour, Female, ICEP, Sedentary Behavior
Abstract

ObjectivesPhysical inactivity and sedentary behaviour are associated with higher breast cancer risk in observational studies, but ascribing causality is difficult. Mendelian randomisation (MR) assesses causality by simulating randomised trial groups using genotype. We assessed whether lifelong physical activity or sedentary time, assessed using genotype, may be causally associated with breast cancer risk overall, pre/post-menopause, and by case-groups defined by tumour characteristics.MethodsWe performed two-sample inverse-variance-weighted MR using individual-level Breast Cancer Association Consortium case-control data from 130 957 European-ancestry women (69 838 invasive cases), and published UK Biobank data (n=91 105–377 234). Genetic instruments were single nucleotide polymorphisms (SNPs) associated in UK Biobank with wrist-worn accelerometer-measured overall physical activity (nsnps=5) or sedentary time (nsnps=6), or accelerometer-measured (nsnps=1) or self-reported (nsnps=5) vigorous physical activity.ResultsGreater genetically-predicted overall activity was associated with lower breast cancer overall risk (OR=0.59; 95% confidence interval (CI) 0.42 to 0.83 per-standard deviation (SD;~8 milligravities acceleration)) and for most case-groups. Genetically-predicted vigorous activity was associated with lower risk of pre/perimenopausal breast cancer (OR=0.62; 95% CI 0.45 to 0.87,≥3 vs. 0 self-reported days/week), with consistent estimates for most case-groups. Greater genetically-predicted sedentary time was associated with higher hormone-receptor-negative tumour risk (OR=1.77; 95% CI 1.07 to 2.92 per-SD (~7% time spent sedentary)), with elevated estimates for most case-groups. Results were robust to sensitivity analyses examining pleiotropy (including weighted-median-MR, MR-Egger).ConclusionOur study provides strong evidence that greater overall physical activity, greater vigorous activity, and lower sedentary time are likely to reduce breast cancer risk. More widespread adoption of active lifestyles may reduce the burden from the most common cancer in women.

Published
2022

66. A Genetic Locus within the FMN1/GREM1 Gene Region Interacts with Body Mass Index in Colorectal Cancer Risk

Author

Aglago, Elom K., primary, Kim, Andre, additional, Lin, Yi, additional, Qu, Conghui, additional, Evangelou, Marina, additional, Ren, Yu, additional, Morrison, John, additional, Albanes, Demetrius, additional, Arndt, Volker, additional, Barry, Elizabeth L., additional, Baurley, James W., additional, Berndt, Sonja I., additional, Bien, Stephanie A., additional, Bishop, D. Timothy, additional, Bouras, Emmanouil, additional, Brenner, Hermann, additional, Buchanan, Daniel D., additional, Budiarto, Arif, additional, Carreras-Torres, Robert, additional, Casey, Graham, additional, Cenggoro, Tjeng Wawan, additional, Chan, Andrew T., additional, Chang-Claude, Jenny, additional, Chen, Xuechen, additional, Conti, David V., additional, Devall, Matthew, additional, Diez-Obrero, Virginia, additional, Dimou, Niki, additional, Drew, David, additional, Figueiredo, Jane C., additional, Gallinger, Steven, additional, Giles, Graham G., additional, Gruber, Stephen B., additional, Gsur, Andrea, additional, Gunter, Marc J., additional, Hampel, Heather, additional, Harlid, Sophia, additional, Hidaka, Akihisa, additional, Harrison, Tabitha A., additional, Hoffmeister, Michael, additional, Huyghe, Jeroen R., additional, Jenkins, Mark A., additional, Jordahl, Kristina, additional, Joshi, Amit D., additional, Kawaguchi, Eric S., additional, Keku, Temitope O., additional, Kundaje, Anshul, additional, Larsson, Susanna C., additional, Marchand, Loic Le, additional, Lewinger, Juan Pablo, additional, Li, Li, additional, Lynch, Brigid M., additional, Mahesworo, Bharuno, additional, Mandic, Marko, additional, Obón-Santacana, Mireia, additional, Moreno, Victor, additional, Murphy, Neil, additional, Nan, Hongmei, additional, Nassir, Rami, additional, Newcomb, Polly A., additional, Ogino, Shuji, additional, Ose, Jennifer, additional, Pai, Rish K., additional, Palmer, Julie R., additional, Papadimitriou, Nikos, additional, Pardamean, Bens, additional, Peoples, Anita R., additional, Platz, Elizabeth A., additional, Potter, John D., additional, Prentice, Ross L., additional, Rennert, Gad, additional, Ruiz-Narvaez, Edward, additional, Sakoda, Lori C., additional, Scacheri, Peter C., additional, Schmit, Stephanie L., additional, Schoen, Robert E., additional, Shcherbina, Anna, additional, Slattery, Martha L., additional, Stern, Mariana C., additional, Su, Yu-Ru, additional, Tangen, Catherine M., additional, Thibodeau, Stephen N., additional, Thomas, Duncan C., additional, Tian, Yu, additional, Ulrich, Cornelia M., additional, van Duijnhoven, Franzel JB, additional, Van Guelpen, Bethany, additional, Visvanathan, Kala, additional, Vodicka, Pavel, additional, Wang, Jun, additional, White, Emily, additional, Wolk, Alicja, additional, Woods, Michael O., additional, Wu, Anna H., additional, Zemlianskaia, Natalia, additional, Hsu, Li, additional, Gauderman, W. James, additional, Peters, Ulrike, additional, Tsilidis, Konstantinos K., additional, and Campbell, Peter T., additional

Published
2023
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67. Supplementary Tables 1-4; Supplementary Figures 1-4 from Linking Physical Activity to Breast Cancer Risk via the Insulin/Insulin-like Growth Factor Signaling System, Part 2: The Effect of Insulin/Insulin-like Growth Factor Signaling on Breast Cancer Risk

Author

Drummond, Ann E., primary, Swain, Christopher T.V., primary, Milne, Roger L., primary, English, Dallas R., primary, Brown, Kristy A., primary, Skinner, Tina L., primary, Lay, Jannelle, primary, van Roekel, Eline H., primary, Moore, Melissa M., primary, Gaunt, Tom R., primary, Martin, Richard M., primary, Lewis, Sarah J., primary, and Lynch, Brigid M., primary

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2023
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68. Data from Linking Physical Activity to Breast Cancer Risk via the Insulin/Insulin-like Growth Factor Signaling System, Part 2: The Effect of Insulin/Insulin-like Growth Factor Signaling on Breast Cancer Risk

Author

Drummond, Ann E., primary, Swain, Christopher T.V., primary, Milne, Roger L., primary, English, Dallas R., primary, Brown, Kristy A., primary, Skinner, Tina L., primary, Lay, Jannelle, primary, van Roekel, Eline H., primary, Moore, Melissa M., primary, Gaunt, Tom R., primary, Martin, Richard M., primary, Lewis, Sarah J., primary, and Lynch, Brigid M., primary

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2023
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69. Supplementary Figure from Linking Physical Activity to Breast Cancer Risk via the Insulin/Insulin-like Growth Factor Signaling System, Part 2: The Effect of Insulin/Insulin-like Growth Factor Signaling on Breast Cancer Risk

Author

Drummond, Ann E., primary, Swain, Christopher T.V., primary, Milne, Roger L., primary, English, Dallas R., primary, Brown, Kristy A., primary, Skinner, Tina L., primary, Lay, Jannelle, primary, van Roekel, Eline H., primary, Moore, Melissa M., primary, Gaunt, Tom R., primary, Martin, Richard M., primary, Lewis, Sarah J., primary, and Lynch, Brigid M., primary

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2023
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70. Data from Linking Physical Activity to Breast Cancer Risk via Insulin/Insulin-Like Growth Factor Signaling System, Part 1: The Effect of Physical Activity on the Insulin/Insulin-Like Growth Factor Signaling System

Author

Swain, Christopher T.V., primary, Drummond, Ann E., primary, Milne, Roger L., primary, English, Dallas R., primary, Brown, Kristy A., primary, Chong, Jamie E., primary, Skinner, Tina L., primary, van Roekel, Eline H., primary, Moore, Melissa M., primary, Gaunt, Tom R., primary, Martin, Richard M., primary, Lewis, Sarah J., primary, and Lynch, Brigid M., primary

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2023
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71. Supplementary Figure from Linking Physical Activity to Breast Cancer Risk via Insulin/Insulin-Like Growth Factor Signaling System, Part 1: The Effect of Physical Activity on the Insulin/Insulin-Like Growth Factor Signaling System

Author

Swain, Christopher T.V., primary, Drummond, Ann E., primary, Milne, Roger L., primary, English, Dallas R., primary, Brown, Kristy A., primary, Chong, Jamie E., primary, Skinner, Tina L., primary, van Roekel, Eline H., primary, Moore, Melissa M., primary, Gaunt, Tom R., primary, Martin, Richard M., primary, Lewis, Sarah J., primary, and Lynch, Brigid M., primary

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2023
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72. Figure S1A from Linking Physical Activity to Breast Cancer Risk via Inflammation, Part 1: The Effect of Physical Activity on Inflammation

Author

Swain, Christopher T.V., primary, Drummond, Ann E., primary, Milne, Roger L., primary, English, Dallas R., primary, Brown, Kristy A., primary, Lou, Makayla W.C., primary, Boing, Leonessa, primary, Bageley, Amy, primary, Skinner, Tina L., primary, van Roekel, Eline H., primary, Moore, Melissa M., primary, Gaunt, Tom R., primary, Martin, Richard M., primary, Lewis, Sarah J., primary, and Lynch, Brigid M., primary

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2023
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73. Table S6B from Linking Physical Activity to Breast Cancer Risk via Inflammation, Part 1: The Effect of Physical Activity on Inflammation

Author

Swain, Christopher T.V., primary, Drummond, Ann E., primary, Milne, Roger L., primary, English, Dallas R., primary, Brown, Kristy A., primary, Lou, Makayla W.C., primary, Boing, Leonessa, primary, Bageley, Amy, primary, Skinner, Tina L., primary, van Roekel, Eline H., primary, Moore, Melissa M., primary, Gaunt, Tom R., primary, Martin, Richard M., primary, Lewis, Sarah J., primary, and Lynch, Brigid M., primary

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2023
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74. Figure 1 from Linking Physical Activity to Breast Cancer Risk via Inflammation, Part 1: The Effect of Physical Activity on Inflammation

Author

Swain, Christopher T.V., primary, Drummond, Ann E., primary, Milne, Roger L., primary, English, Dallas R., primary, Brown, Kristy A., primary, Lou, Makayla W.C., primary, Boing, Leonessa, primary, Bageley, Amy, primary, Skinner, Tina L., primary, van Roekel, Eline H., primary, Moore, Melissa M., primary, Gaunt, Tom R., primary, Martin, Richard M., primary, Lewis, Sarah J., primary, and Lynch, Brigid M., primary

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2023
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75. Data from Linking Physical Activity to Breast Cancer via Inflammation, Part 2: The Effect of Inflammation on Breast Cancer Risk

Author

Lou, Makayla W.C., primary, Drummond, Ann E., primary, Swain, Christopher T.V., primary, Milne, Roger L., primary, English, Dallas R., primary, Brown, Kristy A., primary, van Roekel, Eline H., primary, Skinner, Tina L., primary, Moore, Melissa M., primary, Gaunt, Tom R., primary, Martin, Richard M., primary, Lewis, Sarah J., primary, and Lynch, Brigid M., primary

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2023
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76. Table S1 from Linking Physical Activity to Breast Cancer via Inflammation, Part 2: The Effect of Inflammation on Breast Cancer Risk

Author

Lou, Makayla W.C., primary, Drummond, Ann E., primary, Swain, Christopher T.V., primary, Milne, Roger L., primary, English, Dallas R., primary, Brown, Kristy A., primary, van Roekel, Eline H., primary, Skinner, Tina L., primary, Moore, Melissa M., primary, Gaunt, Tom R., primary, Martin, Richard M., primary, Lewis, Sarah J., primary, and Lynch, Brigid M., primary

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2023
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77. Figure S1E from Linking Physical Activity to Breast Cancer via Inflammation, Part 2: The Effect of Inflammation on Breast Cancer Risk

Author

Lou, Makayla W.C., primary, Drummond, Ann E., primary, Swain, Christopher T.V., primary, Milne, Roger L., primary, English, Dallas R., primary, Brown, Kristy A., primary, van Roekel, Eline H., primary, Skinner, Tina L., primary, Moore, Melissa M., primary, Gaunt, Tom R., primary, Martin, Richard M., primary, Lewis, Sarah J., primary, and Lynch, Brigid M., primary

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2023
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78. Table 1 from Linking Physical Activity to Breast Cancer Risk via Inflammation, Part 1: The Effect of Physical Activity on Inflammation

Author

Swain, Christopher T.V., primary, Drummond, Ann E., primary, Milne, Roger L., primary, English, Dallas R., primary, Brown, Kristy A., primary, Lou, Makayla W.C., primary, Boing, Leonessa, primary, Bageley, Amy, primary, Skinner, Tina L., primary, van Roekel, Eline H., primary, Moore, Melissa M., primary, Gaunt, Tom R., primary, Martin, Richard M., primary, Lewis, Sarah J., primary, and Lynch, Brigid M., primary

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2023
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79. Table 1 from Linking Physical Activity to Breast Cancer via Inflammation, Part 2: The Effect of Inflammation on Breast Cancer Risk

Author

Lou, Makayla W.C., primary, Drummond, Ann E., primary, Swain, Christopher T.V., primary, Milne, Roger L., primary, English, Dallas R., primary, Brown, Kristy A., primary, van Roekel, Eline H., primary, Skinner, Tina L., primary, Moore, Melissa M., primary, Gaunt, Tom R., primary, Martin, Richard M., primary, Lewis, Sarah J., primary, and Lynch, Brigid M., primary

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2023
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80. Figure 2 from Linking Physical Activity to Breast Cancer via Inflammation, Part 2: The Effect of Inflammation on Breast Cancer Risk

Author

Lou, Makayla W.C., primary, Drummond, Ann E., primary, Swain, Christopher T.V., primary, Milne, Roger L., primary, English, Dallas R., primary, Brown, Kristy A., primary, van Roekel, Eline H., primary, Skinner, Tina L., primary, Moore, Melissa M., primary, Gaunt, Tom R., primary, Martin, Richard M., primary, Lewis, Sarah J., primary, and Lynch, Brigid M., primary

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2023
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81. Figure 1 from Linking Physical Activity to Breast Cancer via Inflammation, Part 2: The Effect of Inflammation on Breast Cancer Risk

Author

Lou, Makayla W.C., primary, Drummond, Ann E., primary, Swain, Christopher T.V., primary, Milne, Roger L., primary, English, Dallas R., primary, Brown, Kristy A., primary, van Roekel, Eline H., primary, Skinner, Tina L., primary, Moore, Melissa M., primary, Gaunt, Tom R., primary, Martin, Richard M., primary, Lewis, Sarah J., primary, and Lynch, Brigid M., primary

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2023
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82. Figure 3 from Linking Physical Activity to Breast Cancer via Inflammation, Part 2: The Effect of Inflammation on Breast Cancer Risk

Author

Lou, Makayla W.C., primary, Drummond, Ann E., primary, Swain, Christopher T.V., primary, Milne, Roger L., primary, English, Dallas R., primary, Brown, Kristy A., primary, van Roekel, Eline H., primary, Skinner, Tina L., primary, Moore, Melissa M., primary, Gaunt, Tom R., primary, Martin, Richard M., primary, Lewis, Sarah J., primary, and Lynch, Brigid M., primary

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2023
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83. Figure 3 from Linking Physical Activity to Breast Cancer Risk via Inflammation, Part 1: The Effect of Physical Activity on Inflammation

Author

Swain, Christopher T.V., primary, Drummond, Ann E., primary, Milne, Roger L., primary, English, Dallas R., primary, Brown, Kristy A., primary, Lou, Makayla W.C., primary, Boing, Leonessa, primary, Bageley, Amy, primary, Skinner, Tina L., primary, van Roekel, Eline H., primary, Moore, Melissa M., primary, Gaunt, Tom R., primary, Martin, Richard M., primary, Lewis, Sarah J., primary, and Lynch, Brigid M., primary

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2023
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84. Figure 2 from Linking Physical Activity to Breast Cancer Risk via Inflammation, Part 1: The Effect of Physical Activity on Inflammation

Author

Swain, Christopher T.V., primary, Drummond, Ann E., primary, Milne, Roger L., primary, English, Dallas R., primary, Brown, Kristy A., primary, Lou, Makayla W.C., primary, Boing, Leonessa, primary, Bageley, Amy, primary, Skinner, Tina L., primary, van Roekel, Eline H., primary, Moore, Melissa M., primary, Gaunt, Tom R., primary, Martin, Richard M., primary, Lewis, Sarah J., primary, and Lynch, Brigid M., primary

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2023
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85. Figure 4 from Linking Physical Activity to Breast Cancer via Inflammation, Part 2: The Effect of Inflammation on Breast Cancer Risk

Author

Lou, Makayla W.C., primary, Drummond, Ann E., primary, Swain, Christopher T.V., primary, Milne, Roger L., primary, English, Dallas R., primary, Brown, Kristy A., primary, van Roekel, Eline H., primary, Skinner, Tina L., primary, Moore, Melissa M., primary, Gaunt, Tom R., primary, Martin, Richard M., primary, Lewis, Sarah J., primary, and Lynch, Brigid M., primary

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2023
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86. Data from Linking Physical Activity to Breast Cancer Risk via Inflammation, Part 1: The Effect of Physical Activity on Inflammation

Author

Swain, Christopher T.V., primary, Drummond, Ann E., primary, Milne, Roger L., primary, English, Dallas R., primary, Brown, Kristy A., primary, Lou, Makayla W.C., primary, Boing, Leonessa, primary, Bageley, Amy, primary, Skinner, Tina L., primary, van Roekel, Eline H., primary, Moore, Melissa M., primary, Gaunt, Tom R., primary, Martin, Richard M., primary, Lewis, Sarah J., primary, and Lynch, Brigid M., primary

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2023
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88. The Relationship Between Psychological Distress and Physical Activity Is Non-linear and Differs by Domain: a Cross-Sectional Study.

Author

Mizrahi, David, Swain, Christopher T. V., Bruinsma, Fiona, Hodge, Allison, Taylor, Natalie, and Lynch, Brigid M.

Subjects
SEDENTARY lifestyles, LEISURE, CONFIDENCE intervals, CROSS-sectional method, PHYSICAL activity, SCREEN time, SEX distribution, DESCRIPTIVE statistics, RESEARCH funding, INDUSTRIAL hygiene, PSYCHOLOGICAL distress, DOSE-response relationship in biochemistry, SECONDARY analysis, TRANSPORTATION
Abstract

Background : There is increasing evidence for the relationship between physical activity (PA), sedentary behaviour and mental health. Limited data exists on sex-specific associations. We aimed to identify associations between PA dose and domain and television time with psychological distress, including sex-stratified models. Methods: A total of 22,176 adults from the Melbourne Collaborative Cohort Study follow-up 2 cohort (2003–2007) participated in this cross-sectional study. Occupational, household, transport, leisure PA, hours watching television and psychological distress were assessed. Restricted cubic splines were used to examine the relationships between PA domains, television viewing time and psychological distress. Results: The relationships between PA and psychological distress were non-linear (p < 0.05) and differed by PA domain. There were dose-dependent, inverse associations between distress with transport (B[95% CI] = −0.39[−0.49, −0.30]) and leisure PA (B[95% CI] = −0.35[−0.46, −0.25]). The effect estimates for transport and leisure PA with distress were larger for women. For household domain, a U-shaped curve with an elongated tail was seen. Median PA was associated with lower distress compared with lower quantities (B[95% CI] = −0.12[−0.22, −0.03]); however, this association was not evident with increasing household PA. There were no clear associations between occupational PA and distress. Higher television viewing was associated with higher distress (B[95% CI] = 0.16[0.02, 0.30]). Conclusions: Increasing PA and reducing television viewing may contribute to reduced psychological distress, particularly in women. Future interventions should incorporate leisure and transport PA and decrease television viewing to assess the impact on mental health. [ABSTRACT FROM AUTHOR]

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2023
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95. Linking Physical Activity to Breast Cancer Risk via Inflammation, Part 1: The Effect of Physical Activity on Inflammation

Author

Swain, Christopher T.V., primary, Drummond, Ann E., additional, Milne, Roger L., additional, English, Dallas R., additional, Brown, Kristy A., additional, Lou, Makayla W.C., additional, Boing, Leonessa, additional, Bageley, Amy, additional, Skinner, Tina L., additional, van Roekel, Eline H., additional, Moore, Melissa M., additional, Gaunt, Tom R., additional, Martin, Richard M., additional, Lewis, Sarah J., additional, and Lynch, Brigid M., additional

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2023
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96. Linking Physical Activity to Breast Cancer via Inflammation, Part 2: The Effect of Inflammation on Breast Cancer Risk

Author

Lou, Makayla W.C., primary, Drummond, Ann E., additional, Swain, Christopher T.V., additional, Milne, Roger L., additional, English, Dallas R., additional, Brown, Kristy A., additional, van Roekel, Eline H., additional, Skinner, Tina L., additional, Moore, Melissa M., additional, Gaunt, Tom R., additional, Martin, Richard M., additional, Lewis, Sarah J., additional, and Lynch, Brigid M., additional

Published
2023
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97. Leisure time sedentary behaviour and risks of breast, colorectal, and prostate cancer: A Mendelian randomization analysis

Author

Papadimitriou, Nikos, primary, Kazmi, Nabila, additional, Dimou, Niki, additional, Tsilidis, Konstantinos K, additional, Martin, Richard M, additional, Lewis, Sarah J, additional, Lynch, Brigid M, additional, Hoffmeister, Michael, additional, Kweon, Sun-Seog, additional, Li, Li, additional, Milne, Roger L, additional, Sakoda, Lori C, additional, Schoen, Robert E, additional, Phipps, Amanda I, additional, Figueiredo, Jane C, additional, Peters, Ulrike, additional, Dixon-Suen, Suzanne C., additional, Gunter, Marc J, additional, and Murphy, Neil, additional

Published
2023
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98. Status and Trends of Physical Activity Surveillance, Policy, and Research in 164 Countries: Findings From the Global Observatory for Physical Activity—GoPA! 2015 and 2020 Surveys

Author

Ramírez Varela, Andrea, primary, Hallal, Pedro C., additional, Mejía Grueso, Juliana, additional, Pedišić, Željko, additional, Salvo, Deborah, additional, Nguyen, Anita, additional, Klepac, Bojana, additional, Bauman, Adrian, additional, Siefken, Katja, additional, Hinckson, Erica, additional, Oyeyemi, Adewale L., additional, Richards, Justin, additional, Salih Khidir, Elena Daniela, additional, Inoue, Shigeru, additional, Amagasa, Shiho, additional, Jauregui, Alejandra, additional, da Silva, Marcelo Cozzensa, additional, Lee, I-Min, additional, Ding, Melody, additional, Kohl, Harold W., additional, Ekelund, Ulf, additional, Heath, Gregory W., additional, Powell, Kenneth E., additional, Foster, Charlie, additional, Memon, Aamir Raoof, additional, Doumbia, Abdoulaye, additional, Rather, Abdul Roof, additional, Razzaque, Abdur, additional, Diouf, Adama, additional, Hino, Adriano Akira, additional, Damasceno, Albertino, additional, Abebe, Alem Deksisa, additional, Florindo, Alex Antonio, additional, Mannocci, Alice, additional, Aringazina, Altyn, additional, Juričan, Andrea Backović, additional, Poffet, Andrea, additional, Decelis, Andrew, additional, Carlin, Angela, additional, Enescu, Angelica, additional, Ochoa Avilés, Angélica María, additional, Kontsevaya, Anna, additional, Somhegyi, Annamaria, additional, Vuillemin, Anne, additional, El Hamdouchi, Asmaa, additional, Théodore, Asse Amangoua, additional, Masanovic, Bojan, additional, Lynch, Brigid M., additional, Medina, Catalina, additional, del Campo, Cecilia, additional, Abdeta, Chalchisa, additional, Moreways, Changa, additional, Ranasinghe, Chathuranga, additional, Howitt, Christina, additional, Cameron, Christine, additional, Jurakić, Danijel, additional, Martinez-Gomez, David, additional, Tladi, Dawn, additional, Diro, Debrework Tesfaye, additional, Adlakha, Deepti, additional, Mitić, Dušan, additional, Bjelica, Duško, additional, Biernat, Elżbieta, additional, Chisati, Enock M., additional, Lambert, Estelle Victoria, additional, Cerin, Ester, additional, Lee, Eun-Young, additional, Riso, Eva-Maria, additional, Cañete Villalba, Felicia, additional, Assah, Felix, additional, Lovrić, Franjo, additional, Araya-Vargas, Gerardo A., additional, La Torre, Giuseppe, additional, Cruz, Gloria Isabel Niño, additional, Baltaci, Gul, additional, Al Sabbah, Haleama, additional, Nalecz, Hanna, additional, Nashandi, Hilde Liisa, additional, Park, Hyuntae, additional, Revuelta-Sánchez, Inés, additional, Nusurupia, Jackline Jema, additional, Zamora, Jaime Leppe, additional, Kopcakova, Jaroslava, additional, Brazo-Sayavera, Javier, additional, Oppert, Jean-Michel, additional, Nie, Jinlei, additional, Spence, John C., additional, Bradley, John Stewart, additional, Mota, Jorge, additional, Mitáš, Josef, additional, Chen, Junshi, additional, Hylton, Kamilah S, additional, Fromel, Karel, additional, Milton, Karen, additional, Borodulin, Katja, additional, Moustapha, Keita Amadou, additional, Martinez-Folgar, Kevin, additional, Nasreddine, Lara, additional, Christiansen, Lars Breum, additional, Malisoux, Laurent, additional, Malete, Leapetswe, additional, Grepo-Jalao, Lorelie C., additional, Monteiro, Luciana Zaranza, additional, Al Subhi, Lyutha K., additional, Dakskobler, Maja, additional, Alnaji, Majed, additional, Garro, Margarita Claramunt, additional, Hagströmer, Maria, additional, Murphy, Marie H., additional, Mclaughlin, Matthew , additional, Rivera-Morales, Mercedes, additional, Scheinowitz, Mickey, additional, Shkodra, Mimoza, additional, Piątkowska, Monika, additional, Chaudhury, Moushumi, additional, Alrashdi, Naif Ziyad, additional, Mutrie, Nanette, additional, Murphy, Niamh, additional, Ahmad, Norhayati Haji, additional, Obeidat, Nour A., additional, Gómez, Nubia Yaneth Ruiz, additional, Liangruenrom, Nucharapon, additional, Arnesto, Oscar Díaz, additional, Flores-Flores, Oscar, additional, Incarbone, Oscar, additional, Chimeddamba, Oyun, additional, Bovet, Pascal, additional, Magalhães, Pedro, additional, Jousilahti, Pekka, additional, Katewongsa, Piyawat, additional, Gómez, Rafael Alexander Leandro, additional, Shihab, Rawan Awni, additional, Ocansey, Reginald, additional, Veress, Réka, additional, Marine, Richard, additional, Carrizales-Ramos, Rolando, additional, Saeed, Saad Younis, additional, El-Ashker, Said, additional, Green, Samuel, additional, Kasoma, Sandra, additional, Beretervide, Santiago, additional, Baldew, Se-Sergio, additional, Nichols, Selby, additional, Khoo, Selina, additional, Hosseini, Seyed Ali, additional, Goenka, Shifalika, additional, Gholamalishahi, Shima, additional, Kosen, Soewarta, additional, Compernolle, Sofie, additional, Enescu, Stefan Paul, additional, Popovic, Stevo, additional, Paudel, Susan, additional, Andrade, Susana, additional, Titze, Sylvia, additional, Davidson, Tamu, additional, Dusingizimana, Theogene, additional, Dorner, Thomas E., additional, Kolbe-Alexander, Tracy L., additional, Huong, Tran Thanh, additional, Sychareun, Vanphanom, additional, Jarevska-Simovska, Vera, additional, Puloka, Viliami Kulikefu, additional, Onywera, Vincent, additional, Wendel-Vos, Wanda, additional, Dionyssiotis, Yannis, additional, and Pratt, Michael, additional

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2023
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