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324 results on '"Lorenzo-Luaces, Lorenzo"'

67. Commentary: Holy grails, personalized medicine, and the public health burden of psychopathology – a reflection on Ahuvia et al. (2023).

Author

Lorenzo‐Luaces, Lorenzo

Subjects
*INTERNET, *BEHAVIOR therapy, *MEDICAL care, *MACHINE learning, *TREATMENT effectiveness, *DEPRESSION in adolescence, *MENTAL depression, *TEENAGERS' conduct of life, *EVALUATION, *ADOLESCENCE
Abstract

Clinical psychology and psychiatry have many 'holy grails' or research findings that are widely sought after but remain elusive. The use of machine learning (ML) models for treatment selection is one of these holy grails. Ahuvia et al. (Journal of Child Psychology and Psychiatry, 2023) recently analyzed a large trial (n = 996) of two distinct single‐session interventions (SSIs) for internalizing distress and found little evidence that an ML model could predict differential treatment response. I discuss potential avenues for advancing SSI research. One avenue is the dissemination and implementation of SSIs, including how they interact with other treatments in routine care. Quantifying and critically questioning the promises of holy grails like ML models is sorely needed. Using simulation modeling to evaluate the relative merits of using ML models for treatment selection or using SSIs versus other treatment strategies may be another path forward. [ABSTRACT FROM AUTHOR]

Published
2024
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78. An Online Wellness Intervention: Investigating the Efficacy of the Common Elements Toolbox

Author

Lorenzo-Luaces, Lorenzo

Subjects
depression, Medicine and Health Sciences, Social and Behavioral Sciences
Abstract

This is a pre-registered analysis plan for our randomized controlled trial (RCT) "An Online Wellness Intervention: Investigating the Efficacy of the Common Elements Toolbox" (NCT05379881). The RCT is registered in clinicaltrials.gov: https://clinicaltrials.gov/ct2/show/NCT05379881. This is a two-arm (1:1 allocation) RCT comparing short (i.e., 2-week) and longer-term (i.e., 8 weeks) depression and anxiety changes in online workers randomized to received the Common Elements Toolbox (COMET) or a waiting list control (WLC). The trial aims to (1) assess the efficacy of COMET on primary (1a) and secondary outcomes (1b; see below). Additionally, we (2) aimed to build a prediction algorithm to identify individuals who most strongly respond to COMET. We determined the choice of control condition by using the Pragmatic Model for Comparator Selection in Health-Related Behavioral Trials. This framework specifies that no one control group is optimal. Instead, it recommends that the primary aim of the trial and limitations and barriers must be considered when choosing a control condition. While some control groups like sham controls and active placebos are traditionally thought to provide a lot of rigor, they may not be the best control group in any specific study. One consideration in designing our trial is that the efficacy of SSIs in general has been well-established in youth. The efficacy of SSIs in adults and of COMET specifically is not as well-established (see Wasil et al., 2021). Thus, the early state of research on COMET's efficacy would be one factor supporting the use of a WLC. Another important consideration in choosing a comparator is that the aim of single-session interventions like COMET is to make treatment more scalable. Because the intervention is freely available, the consideration of whether it is more effective than a well-controlled sham or placebo is not relevant. If COMET was no more effective than, for example psychoeducation on dream interpretation or tapping, but all interventions were more effective than a WLC, *all other factors being equal,* COMET would be preferable because it is meant to be a bona-fide intervention that uses evidence-based psychological principles.

Published
2022
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80. Is the Pen Mightier than the App: Cross-sectional Survey of Willingness to use Internet-based vs. Bibliotherapy Interventions in a U.S Representative Sample

Author

De Jesús-Romero, Robinson, Lorenzo-Luaces, Lorenzo, and Wasil, Akash

Subjects
psychotherapy, book, depression, self-help, intervention, mental health
Abstract

Study aiming to explore the relative attitudes of individuals toward using self-help in a book print media (i.e., bibliotherapy) vs. internet-based format (i.e., DMHIs).

Published
2022
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81. An Online Wellness Intervention for American College Students: Investigating the Efficacy of The Common Elements Toolbox (COMET)

Author

Wasil, Akash, Steinberg, Joshua, Palermo, Emma, Lorenzo-Luaces, Lorenzo, Strunk, Daniel, Wilks, Chelsey, and DeRubeis, Robert

Subjects
FOS: Psychology, Clinical Psychology, education, Psychology, Social and Behavioral Sciences
Abstract

We are conducting a randomized controlled trial of an online single-session intervention to improve mental health and wellness among college students.

Published
2022
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86. Efficacy and moderators of cognitive therapy versus behavioural activation for adults with depression: study protocol of a systematic review and meta-analysis of individual participant data

Author

Driessen, Ellen, primary, Cohen, Zachary D., additional, Lorenzo-Luaces, Lorenzo, additional, Hollon, Steven D., additional, Richards, David A., additional, Dobson, Keith S., additional, Dimidjian, Sona, additional, Delgadillo, Jaime, additional, Vázquez, Fernando L., additional, McNamara, Kathleen, additional, Horan, John J., additional, Gardner, Pauline, additional, Oei, Tian P., additional, Mehta, Anuj H. P., additional, Twisk, Jos W. R., additional, Cristea, Ioana A., additional, and Cuijpers, Pim, additional

Published
2022
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99. History of Depression

Author

Horwitz, Allan V., Wakefield, Jerome C., Lorenzo-Luaces, Lorenzo, DeRubeis, Robert J., book editor, and Strunk, Daniel R., book editor

Published
2017
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