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52. Subclinical Vascular Brain Lesions in Young Adults With Acute Ischemic Stroke.

Author

De Giuli, Valeria, Grassi, Mario, Besana, Michele, Zedde, Marialuisa, Zini, Andrea, Lodigiani, Corrado, Marcheselli, Simona, Cavallini, Anna, Micieli, Giuseppe, Rasura, Maurizia, DeLodovici, Maria Luisa, Tomelleri, Giampaolo, Checcarelli, Nicoletta, Chiti, Alberto, Giorli, Elisa, Del Sette, Massimo, Tancredi, Lucia, Toriello, Antonella, Braga, Massimiliano, and Morotti, Andrea

Published
2022
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53. Interaction between proatherosclerotic factors and right-to-left shunt on the risk of cryptogenic stroke: the Italian Project on Stroke in Young Adults

Author

Pezzini, Alessandro, Grassi, Mario, Lodigiani, Corrado, Patella, Rosalba, Gandolfo, Carlo, Zini, Andrea, Musolino, Rossella, Calabrò, Rocco Salvatore, Bovi, Paolo, Adami, Alessandro, DeLodovici, Maria Luisa, Del Zotto, Elisabetta, Rota, Lidia Luciana, Rasura, Maurizia, Del Sette, Massimo, Spalloni, Alessandra, Giossi, Alessia, Volonghi, Irene, Casoni, Federica, Cerrato, Paolo, Costa, Paolo, Magoni, Mauro, Toriello, Antonella, Paciaroni, Maurizio, Volta, Giorgio Dalla, Iacoviello, Licia, and Padovani, Alessandro

Published
2012
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55. Predictors of Migraine Subtypes in Young Adults With Ischemic Stroke: The Italian Project on Stroke in Young Adults

Author

Pezzini, Alessandro, Grassi, Mario, Lodigiani, Corrado, Patella, Rosalba, Gandolfo, Carlo, Casoni, Federica, Musolino, Rossella, Salvatore Calabrò, Rocco, Bovi, Paolo, Adami, Alessandro, DeLodovici, Maria Luisa, Del Zotto, Elisabetta, Rota, Lidia Luciana, Rasura, Maurizia, Del Sette, Massimo, Giossi, Alessia, Volonghi, Irene, Zini, Andrea, Cerrato, Paolo, Costa, Paolo, Magoni, Mauro, Iacoviello, Licia, and Padovani, Alessandro

Published
2011
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57. Thromboprofilaxys With Fondaparinux vs. Enoxaparin in Hospitalized COVID-19 Patients: A Multicenter Italian Observational Study

Author

Russo, Vincenzo, primary, Cardillo, Giuseppe, additional, Viggiano, Giuseppe Vito, additional, Mangiacapra, Sara, additional, Cavalli, Antonella, additional, Fontanella, Andrea, additional, Agrusta, Federica, additional, Bellizzi, Annamaria, additional, Amitrano, Maria, additional, Iannuzzo, Mariateresa, additional, Sacco, Clara, additional, Lodigiani, Corrado, additional, Castaldo, Giampiero, additional, and Di Micco, Pierpaolo, additional

Published
2020
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60. Venous and arterial thromboembolic complications in COVID-19 patients admitted to an academic hospital in Milan, Italy

Author

Lodigiani, Corrado, primary, Iapichino, Giacomo, additional, Carenzo, Luca, additional, Cecconi, Maurizio, additional, Ferrazzi, Paola, additional, Sebastian, Tim, additional, Kucher, Nils, additional, Studt, Jan-Dirk, additional, Sacco, Clara, additional, Bertuzzi, Alexia, additional, Sandri, Maria Teresa, additional, and Barco, Stefano, additional

Published
2020
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61. Design and rationale of a randomized, placebo-controlled trial on the efficacy and safety of sulodexide for extended treatment in elderly patients after a first venous thromboembolism

Author

Palareti, Gualtiero, primary, Legnani, Cristina, additional, Antonucci, Emilia, additional, Zorzi, Serena, additional, Bignamini, Angelo A., additional, Lodigiani, Corrado, additional, Tosetto, Alberto, additional, Bertù, Lorenza, additional, Pengo, Vittorio, additional, Testa, Sophie, additional, Ageno, Walter, additional, Prisco, Domenico, additional, Prandoni, Paolo, additional, and Poli, Daniela, additional

Published
2020
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62. FONDENOXAVID: A Retrospective Analysis on Utility of Thromboprophylaxis with Fondaparinux and Enoxaparin in Patients with COVID19 Infection in Italy

Author

Viggiano, Giuseppe Vito, primary, Cardillo, Giuseppe, additional, Russo, Vincenzo, additional, Mangiacapra, Sara, additional, Cavalli, Antonella, additional, Pesci, Chiara, additional, Fontanella, Andrea, additional, Agrusta, Federica, additional, Bellizzi, Annamaria, additional, Amitrano, Maria, additional, Iannuzzo, Mariateresa, additional, Sacco, Clara, additional, Lodigiani, Corrado, additional, and Di Micco, Pierpaolo, additional

Published
2020
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64. Clonal Megakaryocyte Dysplasia with Normal Blood Values Is a Distinct Myeloproliferative Neoplasm.

Author

Barosi, Giovanni, Rosti, Vittorio, Massa, Margherita, Campanelli, Rita, Villani, Laura, Catarsi, Paolo, Carolei, Adriana, Abbà, Carlotta, Lodigiani, Corrado, Primignani, Massimo, Gregato, Giuliana, Bertolini, Francesco, Magrini, Umberto, and Gale, Robert Peter

Subjects
MYELOPROLIFERATIVE neoplasms, DYSPLASIA, MYELOFIBROSIS, DISEASE progression, BONE marrow, CONFIDENCE intervals
Abstract

Introduction: In 1991, we reported 18 persons with a clinical-pathologic entity and termed atypical myeloproliferative disorder because they did not meet the contemporary diagnostic criteria for a myeloproliferative neoplasm. We sought to gain further knowledge on this disease entity. Methods: This retrospective cohort study included consecutive subjects registered in the database of the Center for the Study of Myelofibrosis in Pavia, Italy, from 1998 to 2020 (June), and diagnosed with atypical myeloproliferative disorder according to our adjudicated criteria. We studied clinical, histological, cytogenetic, and molecular covariates and risks of thrombosis, disease progression, and death. Data were compared with those of concurrent subjects with prefibrotic myelofibrosis. Results: Fifteen new subjects with atypical myeloproliferative disorder were identified. Seven were male. Median age was 50 years (IQR, 41–54 years). Thirteen were diagnosed with a synchronous symptomatic or incidentally detected thrombotic event. The bone marrow showed megakaryocyte hyperplasia with dysplasia. JAK2V617F was present in 10 subjects and CALR mutation in one. No other somatic mutations were identified in next generation sequencing. After a median follow-up of 101 months (IQR, 40–160 months), no subject had disease progression or blast transformation. Incidence of post-diagnosis or recurrent thrombosis was 3.9 events (95% confidence interval, 3.5–4.0) and 5.0 events (4.6–5.6) per 100 person-years. Features of subjects with atypical myeloproliferative disorder differed markedly from those of 546 subjects with prefibrotic myelofibrosis. Conclusion: Our data indicate that these 15 persons have a distinct myeloproliferative neoplasm. We propose naming this new disorder clonal megakaryocyte dysplasia with normal blood values. [ABSTRACT FROM AUTHOR]

Published
2022
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66. Rituximab for treatment of autoimmune acquired platelet function disorders: description of two cases of acquired Glanzmann thrombasthenia and one case of acquired delta storage pool disease

Author

Alberelli, Maria Adele, Bacci, Monica, Marchetti, Marina, Ferrazzi, Paola, Dragani, Alfredo, Gamba, Sara, Landolfi, Raffaele, Falanga, Anna, Lodigiani, Corrado, De Candia, Erica, Landolfi, Raffaele (ORCID:0000-0002-7913-8576), De Candia, Erica (ORCID:0000-0003-0942-2819), Alberelli, Maria Adele, Bacci, Monica, Marchetti, Marina, Ferrazzi, Paola, Dragani, Alfredo, Gamba, Sara, Landolfi, Raffaele, Falanga, Anna, Lodigiani, Corrado, De Candia, Erica, Landolfi, Raffaele (ORCID:0000-0002-7913-8576), and De Candia, Erica (ORCID:0000-0003-0942-2819)

Abstract

N/A

Published
2019

67. Efficacy of Rivaroxaban for thromboprophylaxis after Knee Arthroscopy (ERIKA)

Author

Camporese, Giuseppe, Bernardi, Enrico, Noventa, Franco, Bosco, Mario, Monteleone, Giuseppe, Santoro, Luca, Bortoluzzi, Cristiano, Freguja, Stefano, Nardin, Michela, Marullo, Matteo, Zanon, Giacomo, Mazzola, Claudio, Damiani, Guido, Maniscalco, Pietro, Imberti, Davide, Lodigiani, Corrado, Becattini, Cecilia, Tonello, Chiara, Agnelli, Giancarlo, Tonello, C., Bosco, M., Monteleone, G., Santoro, L., Santoliquido, A., Di Giorgio, A., Nicolardi, E., Biondi, G., Fieri, C., Dall’Acqua, D., De Matthaeis, A., Giannotta, L., Masciangelo, M., Taccardo, G., De Vitis, R., Militerno, A., Serpieri, S., Cilli, V., Bortoluzzi, C., Freguja, S., Nardin, M., Parisi, R., Marullo, M., Azzaretti, A., Zanon, G., Mazzola, C., Damiani, G., Gori, A., Cassola, P., Zabzuni, D., Lodigiani, C., Volpi, P., Bait, C., Vitali, S., Vedovati, MARIA CRISTINA, Di Micco, P., Dimaro, P., Ghirarduzzi, A., and Veropalumbo, R.

Subjects
Adult, Male, medicine.medical_specialty, Knee Joint, Anterior cruciate ligament reconstruction, medicine.medical_treatment, 030204 cardiovascular system & hematology, Placebo, Asymptomatic, Arthroscopy, 03 medical and health sciences, 0302 clinical medicine, Double-Blind Method, Rivaroxaban, Risk Factors, Settore MED/41 - ANESTESIOLOGIA, medicine, Humans, Bleeding, Prophylaxis, Venous thromboembolism, Hematology, 030212 general & internal medicine, Meniscectomy, Venous Thrombosis, Settore MED/12 - Gastroenterologia, Knee arthroscopy, Anterior Cruciate Ligament Reconstruction, medicine.diagnostic_test, business.industry, Absolute risk reduction, Middle Aged, Surgery, Relative risk, Female, medicine.symptom, business, Factor Xa Inhibitors, medicine.drug
Abstract

SummaryWithout thromboprophylaxis, knee arthroscopy (KA) carries a low to moderate risk of venous thromboembolism. Over 5 million arthroscopies are performed worldwide yearly. It was our study objective to assess the efficacy and safety of rivaroxaban for thromboprophylaxis after therapeutic KA. Patients undergoing KA in nine Italian teaching or community hospitals were allocated to once-daily rivaroxaban (10 mg) or placebo for seven days in a phase II, multicentre, double-blind, placebo-controlled randomised trial. The primary efficacy outcome was a composite of all-cause death, symptomatic thromboembolism and asymptomatic proximal DVT at three months; major bleeding represented the primary safety outcome. All patients underwent whole-leg ultrasonography at day 7(+1), or earlier if symptomatic. A total of 241 patients were randomised (122 rivaroxaban, 119 placebo), and 234 completed the study. The primary efficacy outcome occurred in 1/120 of the rivaroxaban group and in 7/114 of the placebo group (0.8% vs 6.1%, respectively, p=0.03; absolute risk difference, −5.3%, 95% CI, −11.4 to −0.8; crude relative risk 0.14, 95% CI, 0.02 to 0.83; number-needed-to-treat=19). No major bleedings were observed. We found no association between different arthroscopic procedures and thrombotic events. Small sample size, high exclusion rate, and low number of anterior cruciate ligament reconstruction procedures are the main limitations of our study. In conclusion, a seven-day course of 10-mg rivaroxaban may be safely employed for thromboprophylaxis after KA. Whether prophylaxis after KA should be given to all patients, or to selected “high-risk” subjects, remains to be determined. A larger trial to verify our preliminary results is warranted.

Published
2016
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68. Screening for Fabry disease in patients with ischaemic stroke at young age: the Italian Project on Stroke in Young Adults

Author

Poli, L., Zedde, Marialuisa, Zini, Andrea, Del Sette, Massimo, Lodigiani, Corrado, Spalloni, Alessandra, Di Lisi, Filomena, Toriello, Antonella, Piras, Valeria, Stilo, Cesare, Tomelleri, Giampaolo, Tancredi, Lucia, Paciaroni, Maurizio, Silvestrelli, Giorgio, Adami, Alessandro, Costa, P., Morotti, A., De Giuli, V., Caria, F., Gamba, Massimo, Malferrari, Giovanni, Simone, Anna Maria, Musolino, Rossella, Giorli, Elisa, Banfi, Elena, Marcheselli, Simona, Rasura, Maurizia, Pugliese, Nicola, Melis, Maurizio, Bovi, Paolo, Padovani, A., Burlina, A., Pezzini, A, Del Zotto, Elisabetta, Giossi, Alessia, Sessa, Maria, Gilberti, Nicola, Magoni, Mauro, Ferrazzi, Paola, Librã¨, Luca, Rota, Lidia Luciana, Patella, Rosalba, Calabrã², Rocco Salvatore, Bramanti, Placido, La Spina, Paolo, Finocchi, Cinzia, Balestrino, Maurizio, Bruno, Chiara, Massucco, Davide, Gandolfo, Carlo, Traverso, Elisabetta, Delodovici, Maria Luisa, Verrengia, Elena Pinuccia, Carimati, Federico, Bono, GIORGIO GIOVANNI, Dell'Acqua, Maria Luisa, Bigliardi, Guido, Vandelli, Laura, Nichelli, Paolo Frigio, Carletti, Monica, Cerrato, Paolo, Iacoviello, Licia, Di Castelnuovo, Augusto, de Gaetano, Giovanni, Grassi, Mario, Locatelli, Giampiero, Caso, Valeria, D'Amore, Cataldo, Agnelli, Giancarlo, Checcarelli, Nicoletta, Guidotti, Mario, Arnaboldi, Marco, Giacalone, Giacomo, Zanoli, Elisa, Cavallini, Anna, Persico, Alessandra, Micieli, Giuseppe, Chiti, Alberto, Orlandi, Giovanni, Marchi, Piernicola, Lanari, Alessia, Ciccone, Alfonso, Cucurachi, Laura, Bonifati, Marco Domenico, and Marcello, Norina

Subjects
Pediatrics, medicine.medical_specialty, Neurology, 030204 cardiovascular system & hematology, Fabry disease, ischaemic, stroke, young, Neurology (clinical), Brain ischemia, 03 medical and health sciences, 0302 clinical medicine, Ischaemic stroke, Medicine, In patient, cardiovascular diseases, Young adult, Stroke, business.industry, medicine.disease, Young age, business, 030217 neurology & neurosurgery
Published
2017
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69. Rituximab for treatment of autoimmune acquired platelet function disorders: description of two cases of acquired Glanzmann thrombasthenia and one case of acquired delta storage pool disease

Author

Alberelli, Maria Adele, primary, Bacci, Monica, additional, Marchetti, Marina, additional, Ferrazzi, Paola, additional, Dragani, Alfredo, additional, Gamba, Sara, additional, Landolfi, Raffaele, additional, Falanga, Anna, additional, Lodigiani, Corrado, additional, and De Candia, Erica, additional

Published
2019
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71. Persistence on apixaban in atrial fibrillation patients: a retrospective multicentre study

Author

Verdecchia, Paolo, primary, D’Onofrio, Antonio, additional, Russo, Vincenzo, additional, Fedele, Francesco, additional, Adamo, Francesco, additional, Benedetti, Giulia, additional, Ferrante, Fabio, additional, Lodigiani, Corrado, additional, Paciullo, Francesco, additional, Aita, Adolfo, additional, Bartolini, Claudia, additional, Molini, Maria Gabriella, additional, Di Lenarda, Andrea, additional, Mazzone, Carmine, additional, Scotti, Lorenza, additional, Lanati, Elena Paola, additional, and Iorio, Arianna, additional

Published
2019
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72. Low Rate of Intrahospital Deep Venous Thrombosis in Acutely Ill Medical Patients: Results From the AURELIO Study

Author

Loffredo, Lorenzo, primary, Arienti, Vincenzo, additional, Vidili, Gianpaolo, additional, Cogliati, Chiara, additional, Battaglia, Simona, additional, Perri, Ludovica, additional, Di Giulio, Rosella, additional, Bernardini, Sciaila, additional, Summa, Maria Luna, additional, Sciacqua, Angela, additional, Perticone, Francesco, additional, Boddi, Maria, additional, Di Minno, Giovanni, additional, Lodigiani, Corrado, additional, Pietrangelo, Antonello, additional, Farcomeni, Alessio, additional, Violi, Francesco, additional, Basili, Stefania, additional, Pignatelli, Pasquale, additional, Ferro, Domenico, additional, Rossi, Elisabetta, additional, Casciaro, Marco Antonio, additional, Pirillo, Lohengrin Stefania, additional, Palumbo, Ilaria Maria, additional, Pannunzio, Arianna, additional, Pesci, Ludovica, additional, Baldini, Lorenzo, additional, Meloni, Pier Luigi, additional, Sauchella, Assunta, additional, Melis, Sara, additional, Berria, Maria, additional, Cringoli, Maurizio, additional, Blanca, Deborah, additional, Casella, Francesco, additional, Ettorre, Evaristo, additional, Cacciafesta, Mauro, additional, Vegetti, Alberto, additional, Crociani, Andrea, additional, Donnarumma, Emilia, additional, Pacciani, Giulia, additional, Rovereto, Rossella, additional, Lunardi, Sarah, additional, Tufano, Antonella, additional, and Pacetti, Veronica, additional

Published
2019
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73. Is there a relationship between factor V Leiden and type 2 diabetes?

Author

Librè Luca, Di Micco Pierpaolo, Ferrazzi Paola, Lodigiani Corrado, Genovese Stefano, Quaglia Ilaria, and Rota Lidia

Subjects
Medicine
Abstract

Abstract Background Diabetes is well known risk factor for thrombotic events. The association between diabetes and venous thromboembolism is still matter of debate. However, during diabetes an acquired thrombophilia is present and is due to the non-enzymatic glycosilation of clotting inhibitors as antithrombin thus leading to hypercoagulable state. A possibile relationship between the presence of FVL gene variant in type 1 or type 2 diabetes has been hypothysed by several reports in the Literature with non-univocal findings. Patients and methods Retrospectively we analysed nearly 7000 patients referred to our Thrombosis Center for venous thromboembolism (VTE) then we selected 115 patients underwent to the screening for inherited thrombophilia. All selected patients were divided in 2 groups: the first group (group A) included 64 patients with previous VTE and carriers of factor V Leiden, while the second group (group B) included 51 patients with previous VTE and evetually carriers of thrombophilic defects other than factor V Leiden. Patients of group B acted as control group. 75 g oral glucose tolerance Test (OGTT) recommended by WHO was perfomed to all subjects in the study in order to screen subjects with glucose reduced tolerance or subjects with inducible diabetes. Statistical analysis was performed with STATA 6 http://www.stata.com with Student t test for unpaired data, with χ2 test or with Fisher exact test where appropriated; differences were considered to be significant if p < 0.05. Results We did not find sifferences between glycaemia at baseline and after OGTT between patients with VTE carriers of FVL compared to non-carriers of FVL. We found a relevant increase in the prevalence of IGT and diabetes between patients with VTE carriers of FVL compared to non-carriers of FVL although this increase did not raise statistical significance. Discussion our data pointed out an interesting aspect of the linking between FVL gene variant, diabetes and atherothrombosis and other vascular complications, although data on larger population are needed; this aspect may be another relevant topic of research based because also a link between the pathogenesis of venous thrombosis and atherothrombosis has been recently reported in the Literature.

Published
2009
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75. Homocysteine, MTHFR C677T gene polymorphism, folic acid and vitamin B 12 in patients with retinal vein occlusion

Author

Gaspari Giorgio, Bellatorre Alessandro, Rossi Lisa, Quaglia Ilaria, Di Micco Pierpaolo, Ferrazzi Paola, Rota Lidia, and Lodigiani Corrado

Subjects
retinal vein occlusion, thrombophilia, homocysteine, MTHFR C677T, folic acid, Diseases of the blood and blood-forming organs, RC633-647.5
Abstract

Abstract Background Many available data have suggested that hyperhomocysteinaemia, an established independent risk factor for thrombosis (arterial and venous), may be associated with an increased risk of retinal vein occlusion (RVO). Aim of the study To evaluate homocysteine metabolism in consecutive caucasian patients affected by RVO from Northern Italy. Patients and Methods 69 consecutive patients from Northern Italy (mean age 64.1 ± 14.6 yy) with recent RVO, were tested for plasma levels of homocysteine (tHcy: fasting and after loading with methionine), cyanocobalamine and folic acid levels (CMIA-Abbot) and looking for MTHFR C677T mutation (Light Cycler-Roche) and compared to 50 volunteers, enrolled as a control group. Results Fasting levels of tHcy were significantly higher in patients than in controls: mean value 14.7 ± 7.7 vs 10.2 ± 8 nmol/ml. Post load levels were also significantly higher: mean value 42.7 ± 23.7 vs 30.4 ± 13.3 nmol/ml; Total homocysteine increase was also evaluated (i.e. Δ-tHcy) after methionine load and was also significantly higher in patients compared to control subjects: mean Δ-tHcy 27.8 ± 21.5 vs 21.0 ± 16 nmol/ml (normal value < 25 nmol/ml). Furthermore, patients affected by RVO show low folic acid and/or vitamin B12 levels, although differences with control group did not reach statistical significance. Heterozygous and homozygous MTHFR mutation were respectively in study group 46% and 29% vs control group 56% and 4%. Conclusion our data confirm that hyperhomocysteinaemia is a risk factor for RVO, and also that TT genotype of MTHFR C677T is more frequently associated with RVO: if the mutation per se is a risk factor for RVO remains an open question to be confirmed because another study from US did not reveal this aspect. Hyperomocysteinemia is modifiable risk factor for thrombotic diseases. Therefore, a screening for tHcy plasma levels in patients with recent retinal vein occlusion could allow to identify patients who might benefit from supplementation with vitamins and normalization of homocysteine levels, in fasting and after methionine load.

Published
2005
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76. Outcomes in Newly Diagnosed Atrial Fibrillation and History of Acute Coronary Syndromes: Insights from GARFIELD-AF

Author

Butler, Amy, Elmersson, Micael, Egilsson, Arnor, Borjesson, Ulf, Svard, Gunnar, Liu, Bo, Lindh, Anders, Olsson, Lars-Bertil, Gustaysson, Mikael, Andersson, Lars, Benson, Lars, Bothin, Claes, Hajimirsadeghi, Ali, Martinsson, Bjorn, Ericsson, Marianne, Ohlsson, Ake, Lindvall, Hakan, Svensson, Peter, Thorne, Katarina, Handel, Hans, Platonov, Pyotr, Bernsten, Fredrik, Timberg, Ingar, Crisby, Milita, Karlsson, Jan-Erik, Andersson, Agneta, Malmqvist, Lennart, Engdahl, Johan, Thulin, Jorgen, Hot-Bjelak, Aida, Jensen, Steen, Debrunner, Johann, Beer, Juerg H., Shah, Dipen, Rudyk, Iurii, Tseluyko, Vira, Karpenko, Oleksandr, Zhurba, Svitlana, Kraiz, Igor, Parkhomenko, Oleksandr, Kupnovytska, Iryna, Seredyuk, Nestor, Mostovoy, Yuriy, Ushakov, Oleksiy, Koval, Olena, Kovalskiy, Igor, Svyshchenko, Yevgeniya, Sychov, Oleg, Stanislavchuk, Mykola, Tykhonova, Susanna, Fushtey, Ivan, Murdoch, Will, Chauhan, Naresh, Goodwin, Daryl, Lumley, Louise, Patel, Ramila, Saunders, Philip, Wong, Bennett, Patel, Niranjan, Jhittay, P., Ross, Andrew, Kainth, M. S., Ladha, Karim, Douglas, Kevin, Pickavance, Gill, McDonnell, Joanna, Handscombe, Laura, Gooding, Trevor, Wagner, Helga, Bradshaw, Colin, Bromham, Catherine, Jones, Kevin, Suryani, Shoeb, Coates, Richard, Sarai, Bhupinder, Willcock, W., Sircar, S., Cairns, John, Gilliand, A., Bilas, Roman, Strieder, E., Hutchinson, Peter, Wakeman, Anne, Stokes, Michael, Kirby, Graham, Vishwanathan, Bhaskhar, Vormann, Reinhold, Mueller, Thomas, Mayer, Peter, Horstmeier, Uwe, Eissing, Volker, Hey, Heinz, Leuchtgens, Heinz, Lilienweiss, Volker, Mueller, Heiner, Schubert, Christian, Lauer, Hellmann, Buchner, Thomas, Brauer, Gunter, Kamin, Susanne, Mueller, Karsten, Baumbach, Sylvia, Abdel-Qader, Muwafeg, Ebert, Hans-Holger, Schwencke, Carsten, Bernhardt, Peter, Karolyi, Laszlo, Sievers, Britta, Haverkamp, Wilhelm, Roehnisch, Jens-Uwe, Vertes, Andras, Szantai, Gabor, Menke, Holger, Matoltsy, Andras, Kanakaridisz, Nikosz, Boda, Zoltan, Kis, Erno, Gaszner, Balazs, Juhasz, Ferenc, Kamogawa, Yasuyuki, Fournier, Pierre-Yves, Muller, Jean-Joseph, Marquand, Andre, Delarche, Nicolas, Bantwal, Ganapathi, Faes, Dirk, Verstraete, Stefan, Dominguez, Helena, Topsakal, Ramazan, Centurion, Nestor, Alfredo Sinisi, Victor, Minc, Piotr, Nagy, Andras, Bilo, Grzegorz, Bongiorni, Maria Grazia, Bird, Nigel, Paul, Carolyn, Wadeson, Paul, Hargreaves, Nick, Kostenko, Victor, Tercedor Sanchez, Luis, Tranche Iparraguirre, Salvador, Jimenez Gonzalez, Mercedes, Herreros Melenchon, Juan, Stalby, Per, Yagensky, Andriy, Cameron, Alex, Jacobs, Polly, Juhasz, Gizella, Kancz, Sandor, Laszlo, Zoltan, May, Zsolt, Astridge, Penny, Loghdey, Rehana, Quick, Annette, Yang, Ping, Chen, Yingmin, He, Shenghu, Wang, Yong, Fu, Guosheng, Li, Xin, Wu, Tongguo, Cheng, Xiaoshu, Yan, Xiaowei, Zhao, Ruiping, Chen, Moshui, Xiong, Longgen, Chen, Ping, Jiao, Yang, Guo, Ying, Xue, Li, Yang, Zhiming, Jadhavm, Praveen, Merkely, Bela, Noon, Ebrahim, Habon, Tamas, Polgar, Peter, Szalai, Gabriella, Vangel, Sandor, Sarma, Raghava, Kulkarni, Govind, Engelthaler, Gabriella, Ferenczi, Judit, Chandwani, Prakash, Pothiwala, Rasesh Atulbhai, Purayil, Mohanan Padinhare, Chawla, Kamaldeep, Verheugt, Freek W. A., Ambrosio, Giuseppe, Atar, Dan, Bassand, Jean-Pierre, Costabel, Juan Pablo, Goldhaber, Samuel Z., Goto, Shinya, Egyutt, Mihaly, Martini, Giuliana, Cristina, Leone Maria, Tirafern, Eros, Santoro, Rita, Testa, Sophie, Di Minno, Giovanni, Moia, Marco, Caimi, Teresa Maria, Tessitori, Maria, Cappelli, Roberto, Accogli, Michele, Mariani, Antonio, Feola, Mauro, Raisaro, Arturo, Fattore, Luciano, Mauric, Andrea, Germini, Fabrizio, Tedeschi, Luca, Settimi, Maria, Nicoli, Sergio, Ricciarini, Paolo, Argena, Antonio, Ronchini, Paolo, Bulla, Claudio, Tradati, Filippo, Volpe, Massimo, Avino, Maria D., Seven, Silva, Capucci, Alessandro, Lodigiani, Corrado, Salomone, Enrico, Serviddio, Gaetano, Tondo, Claudio, Golino, Paolo, Mazzone, Carmine, Iacopino, Saverio, Ruiter, J. H., Lucassen, Andreas, Adriaansen, Henk, Bongaerts, Maarten, Pieterse, Mathijs, van Guldener, Coen, Herrman, Johannes, Nierop, S. H. K. P. R., Hoogslag, Pieter, Hermans, Walter, Groenemeijer, B. E., Terpstra, W., Buiks, Cees, Boersma, L. V. A., Berge, Eivind, Sirnes, Per Anton, Gjertsen, Erik, Hole, Torstein, Erga, Knut, Hallaraker, Arne, Skjelvan, Gunnar, Ostrem, Anders, Ghezai, Beraki, Svilaas, Arne, Christersson, Peter, Oien, Torbjorn, Henrichsen, Svein Hoegh, Otterstad, Jan Erik, Berg-Johansen, Jan, Gieroba, Andrzej, Biedrzycka, Malgorzata, Ogorek, Michal, Wozakowska-Kaplon, Beata, Loboz-Grudzien, Krystyna, Jaroslaw, Jaroslaw, Supinski, Wieslaw, Kuzniar, Jerzy, Zaluska, Roman, Hiczkiewicz, Jaroslaw, Swiatkowska-Byczynska, Lucyna, Kucharski, Lech, Gruchala, Marcin, Olszewski, Maciej, Kania, Grzegorz, Krzciuk, Malgorzata, Lajkowski, Zbigniew, Ostrowska-Pomian, Bozenna, Lewczuk, Jerzy, Zinka, Elzbieta, Karczmarczyk, Agnieszka, Chmielnicka-Pruszczynska, Malgorzata, Wozniak-Skowerska, Iwona, Opolski, Grzegorz, Bronisz, Marek, Ogorek, Marcin, Glanowska, Grazyna, Ruszkowski, Piotr, Skonieczny, Grzegorz, Sciborski, Ryszard, Okopien, Boguslaw, Kukla, Piotr, Galbas, Krzysztof, Cymerman, Krzysztof, Jurowiecki, Jaroslaw, Miekus, Pawel, Myszka, Waldemar, Mazur, Stanislaw, Lysek, Roman, Baszak, Jacek, Rusicka-Piekarz, Teresa, Raczak, Grzegorz, Domanska, Ewa, Nessler, Jadwiga, Catanchin, Andrei, Colquhoun, David, Kiat, Hosen, Eccleston, David, French, John, Ayres, Bronte, Blombery, Peter, Phan, Thanh, Rogers, James, O'Donnell, David, Cheol, Sang, Carroll, Patrick, Starmer, Greg, Arstall, Margaret, Binnekamp, Maurits, Lee, Astin, Luton, Robert, Gupta, Milan, Pandey, Amritanshu Shekhar, Cheung, Stephen, Leader, Rolland, Beaudry, Philippe, Ayala-Paredes, Felix, Berlingieri, Joseph, Heath, John, Poirier, Germain, du Preez, Miranda, Schweitzer, Bradley, Nadeau, Reginald, Dhillon, Ripple, Hruczkowski, Tomasz, Lavoie, Andrea, Parkash, Ratika, Cha, James, Coutu, Benoit, MacDonald, Paul, Ramjattan, Brian, Bonet, Jorge, Vizel, Saul, Angaran, Paul, Fikry, Sameh, Mowafy, Ahmed, Katta, Azza, Tawfik, Mazen, Nawar, Moustafa, Sobhy, Mohamed, Abou Seif, Seif Kamal, Khairy, Tarek, Abd El-Aziz, Ahmed, Taha, Nasser, Reda, Ashraf, Elbahry, Atef, Setiha, Mohamed, El Din, Mohamed Gamal, Elkhadem, Magdi, El-Etreby, Adel, Kettles, David, Bayat, Junaid, Siebert, Heidi, Horak, Adrian, Kelfkens, Ynez, Garda, Riaz, Pillay, Thayabran, Guerra, Michele, van Zyl, Louis, Theron, Hendrik, Murray, Andrew, Louw, Rikus, Greyling, Deon, Mntla, Pindile, Ismail, Siddique, Ahmed, Fayzal, Engelbrecht, Johannes, Maharajh, Shambu, Oosthuysen, Wessel, Ueckermann, Veronica, Al Naeemi, Abdullah, Yousef, Ghazi, Bazargani, Nooshin, Alomairi, Munther, Maruthanayagam, Rajan, Singh, Rupesh, Naguib, Ahmed, Ibrahim, Mohamed, Agrawal, Amrish, Nathani, Mukesh, Esheiba, Ehab M., Wassef, Adel, Gupta, Rajeev, Cox, Michael, Beach, Scott, Duffy, Peter, Falkowski, Stephen, Ferrick, Kevin, Franco, Miguel, Kutayli, W. Michael, Sharma, Niraj, Wilson, Vance, Miller, Stephen, Alberts, Mark, Blumberg, Edwin, Canosa, Roddy, Gutowski, Ted, Ison, Rodney, Garcia, Jorge, Mullen, Paul, Noveck, Howard, Rama, Pamela, Reddy, Rajneesh, Williams, Marcus, Nishijima, Daniel, Ferdinand, Keith, Hague, Ihsan, Mendelson, Robert, Pitta, Sridevi, Theodoro, Daniel, Treasure, Charles, Moustafa, Moustafa, Cader, Cas, Pharr, Walter, Oropallo, Alisha, Platt, George, Gujral, Jaspal, Welker, James, Koura, Firas, Lesnik, Jozef, Eltishcheva, Vera, Libis, Roman, Kamalov, Gadel, Belenky, Dmitry, Egorova, Liudmila, Khokhlov, Alexander, Yakupov, Eduard, Zateyshchikov, Dmitry, Barbarash, Olga, Miller, Olga, Mazur, Evgeniy, Zrazhevskiy, Konstantin, Novikova, Tatyana, Moiseeva, Yulia, Polkanova, Elena, Sobolev, Konstantin, Rossovskaya, Maria, Shapovalova, Yulia, Kolesnikova, Alla, Nikolaev, Konstantin, Zemlianskaia, Oksana, Zateyshchikova, Anna, Popov, Sergey, Poltayskaya, Maria, Edin, Anton, Aleksandrova, Elena, Drapkina, Oksana, Vishnevsky, Alexander, Nagibovich, Oleg, Chizhov, Petr, Rachkova, Svetlana, Sergeev, Mikhail, Kurylo, Borys, Ushakov, Alexey, Alvarez Garcia, Pere, Lopez Fernandez, Maria Fernanda, Toran Monserrat, Pere, Marquez Contreras, Emilio, Isart Rafecas, Jordi, Motero Carrasco, Juan, Garcia Pavia, Pablo, Gomez Pajuelo, Casimiro, Rincon Diaz, Luis Miguel, Iglesias Alonso, Luis Fernando, Grande Ruiz, Angel, Merce Klein, Jordi, Gonzalez Juanatey, Jose Ramon, Monte Collado, Ines, Palacin Piquero, Herminia, Brotons Cuixart, Carles, Fernandez Escobar, Esther, Bayo i Llibre, Joan, Corros Vicente, Cecilia, Vida Gutierrez, Manuel, Evans, Paul, Clark, M., Bisatt, John, Litchfield, Jennifer, Fisher, E., Fooks, Tim, Kelsall, Richard, Paul, Neil, Alborough, Elizabeth, Aziz, Michael, Ramesh, C., Wilson, Pete, Franklin, Simon, Fairhead, Sue, Thompson, Julian, Chowan, Hasan, Taylor, Gary, Tragen, Dawn, Parfitt, Matt, Seamark, Claire, Richardson, Mark, Jefferies, Angus, Sharp, Helen, Jones, Hywel, Giles, Claire, Bramley, Matthew, Williams, Philip, Aldegather, Jehad, Wetherell, Simon, Lumb, William, Evans, Phil, Scouller, Frances, Macey, Neil, Rogers, Stephen, Stipp, Yvette, West, Richard, Pinney, Philip, Matthews, John, Pandya, Preeti, Gallagher, Andrew, Railton, T., Davies, Emyr, McClure, Jonathan, Jacobs, Marc, Hutton, Claire, Thompson, R., Sinha, Bijoy, Butter, Keith, Barrow, Susan, Little, Helen, Russell, David, Choudhary, Ulka, Haq, Ikram, Ainsworth, Paul, Jones, Claire, Weeks, Phil, Eden, Jane, Gibbons, Lisa, Glencross, Janet, MacLeod, Alison, Poland, K., Mulolland, Conor, Warke, A., Conn, Paul, Burns, D., Smith, R., Kamath, R., Webster, Jonathan, Hodgins, Ian, Vercoe, Stephen, Roome, Paul, Pinnock, Hilary, Patel, Jayesh, Ali, Amar, Hart, Nigel, Davies, Richard, De-Sousa, Nigel, Neden, Catherine, Danielsen, Mark, Sharma, Purnima, Galloway, Sophia, Hawkins, Charlotte, Oliver, Raife, Aylward, Martin, Pattni, Mira, Irvine, Gordon, Ahmad, Shahid, Rothwell, Catherine, Choudhary, Fiaz, Khalaque, Sabrina, Short, Stephanie, Peters, Sharon, Coulson, Warwick, Roberts, Neil, Coates, Steven, Ward, Ben, Jackson, Daniel, Walton, Steve, Shepherd, Diane, Wong, Toh, Boon, Mark, Deacon, Melanie, Cornelius, David, Davies, Sarah, Ben Frankel, Ben Frankel, Choi, Henry, Sumner, Jon, Myhill, Tim, Estifanos, Salah, Geatch, Diane, Wilkinson, Justin, Veale, Richard, Forshaw, Karen, Hirst, Rob, Zaman, Kashif, Liley, Catherine, Wastling, Rebecca, McEleny, Paul, Beattie, Andre, Cooke, Philip, Wong, Mike, Pugsley, Mark, Dooldeniya, Chaminda, Rogers, Greg, Bennett, James, Muvva, Rajesh, Adam, Matthew, Fox, Robin, Thomas, Nicolas, Cartwright, Simon, Reed, Rory, Randfield, Simon, ACourt, Christine, Flynn, Ann, Halpin, Andrew, Dobson, Simon, Lomax, Louise, Nadaph, Minnal, Goram, Jane, Stoddart, Helen, Simmons, Phil, Shewring, John, Bowen-Simpkins, Emma, Rickenbach, Mark, Munro, Iain, Blenkhorn, Adam, Singh, Bhuwanendu, van Gaal, William, Abhayaratna, Walter, Thomson, Philip, Lehman, Ron, Kilian, Jens, Coulshed, David, Camm, A. John, Fitzmaurice, David A., Illingworth, Laura, Kayani, Gloria, Kakkar, Ajay K., YILMAZ, MEHMET BİRHAN, Taga, Kuniaki, Techigawara, Masaaki, Igarashi, Mono, Watanabe, Hiroshi, Seo, Toshihiko, Hiramitsu, Shinya, Hosokawa, Hiroaki, Hoshiai, Mitsumoto, Hibino, Michitaka, Miyagawa, Koichi, Horie, Hideki, Turpie, Alexander G. G., van Eickels, Martin, Hacke, Werner, Mantovani, Lorenzo G., Misselwitz, Frank, Pieper, Karen S., Kayani, Glo-ria, Fox, Keith A. A., Gersh, Bernard J., Lucas Luciardi, Hector, Gibbs, Harry, Brodmann, Marianne, Cools, Frank, Pereira Barrett, Antonio Carlos, Connolly, Stuart J., Spyropoulos, Alex, Eikelboom, John, Corbalan, Ramon, Hu, Dayi, Nielsen, JOrn Dalsgaard, Ragy, Hany, Raatikainen, Pekka, Le Heuzey, Jean-Yves, Darius, Harald, Keltai, Matyas, Kakkar, Sanjay, Sawhney, Jitendra Pal Singh, Agnelli, Giancarlo, Koretsune, Yukihiro, Sanchez Diaz, Carlos Jerjes, Ten Cate, Hugo, Panchenko, Elizaveta, Lim, Toon Wei, Jacobson, Barry, Oh, Seil, Vinolas, Xavier, Rosenqvist, Marten, Steffel, Jan, Angchaisuksiri, Pantep, Oto, Ali, Parkhomenko, Alex, Al Mahmeed, Wael, Fitzmaurice, David, Chen, Kangning, Zhao, Yusheng, Zhang, Huaiqin, Chen, Jiyan, Cao, Shiping, Wang, Daowen, Yang, Yuejin, Li, Weihua, Li, Hui, Yin, Yuehui, Tao, Guizhou, Kothiwale, Veerappa Annasaheb, Kimura, Teruaki, Raghuraman, Bagirath, Vijan, Vinod Madan, Sawhney, Jitendra, Khan, Aziz, Meena, Ramdhan, Okuda, Fumio, Mizuguchi, Masato, Mukawa, Hiroaki, Chopada, Manojkumar, Abraham, Sunitha, Bisne, Vikas, Vijayaraghavan, Govindan, Roy, Debabrata, Durgaprasad, Rajashekhar, Shankar, A. G. Ravi, Kumar, Sunil, Jain, Dinesh, Bhargava, Kartikeya, Kumar, Vinay, Nagamalesh, Udigala Madappa, Rajput, Rajeeve Kumar, Kanamori, Seishu, Wada, Masamichi, Minagawa, Taro, Ishiguro, Motoyuki, Yamamoto, Kenichi, Kumagai, Koichiro, Katsuda, Yosuke, Yoshida, Keiki, Toyota, Fumitoshi, Mizuno, Yuji, Misumi, Ikuo, Noguchi, Hiroo, Ando, Shinichi, Suetsugu, Tetsuro, Minamoto, Masahiro, Oda, Hiroyuki, Adachi, Susumu, Chiba, Kei, Norita, Hiroaki, Tsuruta, Makoto, Koyanagi, Takeshi, Matsuta, Masahiro, Ito, Kenichiro, Nakano, Masayuki, Shibuya, Mitsuhiro, Stepinska, Janina, Jansky, Petr, Yamamoto, Kunihiko, Haas, Sylvia, Ando, Hiroshi, Higashi, Takayuki, Okada, Megumi, Azakami, Shiro, Komaki, Shinichiro, Kumeda, Kenshi, Murayama, Takashi, Matsumura, Jun, Oba, Yurika, Sonoda, Ryuji, Goto, Kazuo, Minoda, Kotaro, Haraguchi, Yoshikuni, Suefuji, Hisakazu, Miyagi, Hiroo, Kato, Hitoshi, Nakamura, Tsugihiro, Nakamura, Tadashi, Nandate, Hidekazu, Zaitsu, Ryuji, Fujiura, Yoshihisa, Yoshimura, Akira, Numata, Hiroyuki, Ogawa, Jun, Murakami, Kinshiro, Wakasa, Yutaka, Yamasawa, Masanori, Maekawa, Hiromitsu, Abe, Sumihisa, Kihara, Hajime, Tsunoda, Satoru, Saito, Katsumi, Tachibana, Hiroki, Oba, Ichiro, Kuwahata, Takashi, Higa, Satoshi, Gushiken, Masamichi, Eto, Takuma, Chibana, Hidetoshi, Fujisawa, Kazuaki, Shiga, Yuhei, Sumi, Hirokuni, Nagatomo, Toshihisa, Atsuchi, Yoshihiko, Nagoshi, Toshiro, Sanno, Kazuhisa, Hoshino, Fumihiro, Yokota, Naoto, Kameko, Masahiro, Tabuchi, Toshifumi, Ishizawa, Munesumi, Fujiura, Yoshitake, Ikeda, Daisuke, Seto, Taku, Iwao, Tetsu, Ishioka, Norio, Oshiro, Koichi, Tsuchida, Keizo, Hatori, Yutaka, Takeuchi, Motoshi, Takezawa, Hiroto, Kira, Tetsuya, Tada, Masato, Tsuzaki, Ken, Miura, Naoya, Fujisawa, Yasuaki, Furumoto, Wataru, Suzuki, Susumu, Fujisawa, Akinori, Nakamura, Ryosai, Komatsu, Hiroyasu, Fujiki, Rei, Kawano, Shuichi, Nishizawa, Keijiro, Kato, Yoji, Azuma, Junya, Yasui, Kiyoshi, Amano, Toshio, Sekine, Yasuhiro, Honzawa, Tatsuo, Koshibu, Yuichiro, Sakamoto, Yasuhide, Seta, Yukihiro, Miyaguchi, Shingo, Morishita, Kojuro, Samejima, Yasuko, Sasaki, Toyoshi, Iseki, Fumiko, Kobayashi, Toshiyuki, Kano, Hiroshi, Kim, Jaeyoung, Yamaguchi, Hiroshi, Takagi, Yoichi, Pearce, Yoko Onuki, Suzuki, Yasuyuki, Fukui, Takayuki, Nakayama, Toni, Kanai, Hideaki, Kawano, Yoshiyuki, Ino, Tetsuji, Miyoshi, Hironori, Miyamoto, Yasufumi, Shigekiyo, Masahito, Ono, Shimato, Okamoto, Yutaka, Ubukata, Satoshi, Kodera, Kojiro, Oriuchi, Tatsuo, Matsumoto, Naoki, Nagano, Shinjiro, Iwaki, Masaaki, Nakamura, Yuichiro, Miyamoto, Naomasa, Taguchi, Toshifumi, Ashida, Ko, Yoshizawa, Naoto, Agata, Jun, Matsukawa, Seishiro, Arasaki, Osamu, Fukuoka, Shuji, Murakami, Hirofumi, Mishima, Kazuya, Hata, Yoshiki, Sakuma, Ichiro, Obunai, Kotaro, Takamura, Ichiro, Akutsu, Mitsuyuki, Unoki, Toshihide, Go, Yoshinori, Ikemura, Makoto, Morii, Shoji, Marusaki, Shigem, Doi, Hideo, Tanaka, Mitsuru, Kusu-moto, Takaaki, Kakinoki, Shigeo, Ogurusu, Chiga, Murata, Kazuya, Shimoyama, Masaki, Nakatsuka, Masami, Kitami, Yutaka, Nakamura, Yoichi, Oda, Hiroshi, Oyama, Rikimaru, Ageta, Masato, Mita, Teruaki, Nagao, Kazuhiko, Mito, Takafumi, Minami, Junichi, Abe, Mitsunori, Fujii, Masako, Okawa, Makoto, Fujito, Tsuneo, Taniguchi, Toshiya, Ko, Tenei, Kubo, Hiroshi, Imamaki, Mizuho, Akiyama, Masahiro, Ueda, Takashi, Odakura, Hironori, Inagaki, Masahiko, Katsube, Yoshiki, Nakata, Atsuyuki, Tomimoto, Shinobu, Sugishita, Nobuyoshi, Shiga, Yukio, Soma, Akira, Neya, Kazuo, Yoshida, Tetsuro, Akahane, Kunio, Adachi, Sen, Takanaka, Chiei, Matsui, Saori, Kanda, Hirofumi, Kaneko, Masanori, Nagasaka, Shiro, Taguchi, Atsushi, Toru, Shuta, Saito, Kazuyuki, Miyashita, Akiko, Sasaguri, Hiroki, Nariyama, Jin, Hatsuno, Taketo, Iwase, Takash, Sato, Kazuki, Kawai, Kazuya, Kotani, Tomobumi, Tsuji, Tsuyoshi, Sakai, Hirosumi, Nishino, Kiyoshi, Ikeda, Kenichi, Maeda, Kazuo, Shinozuka, Tomohiro, Inoue, Takeshi, Kawakami, Koichi, Kitazumi, Hiromichi, Takagi, Tsutomu, Hamaoka, Mamoru, Kojima, Jisho, Sasaki, Akitoshi, Tsuchiya, Yoshihiro, Bet-suyaku, Tetsuo, Higuchi, Koji, Honda, Masaaki, Hasegawa, Koichi, Baba, Takao, Mineoi, Kazuaki, Koeda, Toshihiko, Hirasawa, Kunihiko, Kumazaki, Toshihide, Nakagomi, Akira, Otaki, Eiji, Shindo, Takashi, Hirayama, Hiroyoshi, Sugimoto, Chikako, Yamagishi, Takashi, Mizuguchi, Ichiro, Sezaki, Kazunori, Niwa, Isamu, Takenaka, Ken, Iiji, Osamu, Taya, Koichi, Kitazawa, Hitoshi, Ueda, Samu, Kakuda, Hirokazu, Ono, Takuya, Oriso, Seizo, Kamata, Junya, Nanke, Toshihiko, Maeda, Itaru, Matsuura, Yoshifusa, Teragawa, Hiroki, Maruyama, Yasuyuki, Takei, Kazuo, Hone, Hajime, Kito, Tetsu-taro, Asano, Hiroshi, Matsushita, Koji, Nakamura, Masaichi, Washizuka, Takashi, Yoshida, Tomoki, Sawano, Masato, Arima, Shinichi, Arai, Hidekazu, Shinohara, Hisanori, Takai, Hiroyuki, Furukawa, Nobufusa, Ota, Akira, Yamamoto, Kentaro, Aoki, Kenji, Yamamoto, Taku, Kasai, Takeaki, Suzuki, Shunji, Suzuki, Shu, Shibata, Nitaro, Watanabe, Masayuki, Nishihata, Yosuke, Arino, Torn, Okuyama, Masaki, Wakiyama, Tetsushi, Kato, Tomoko, Sasagawa, Yasuo, Tana, Takeshi, Tumelero, Rogerio Tadeu, Maia, Lilia, de Almeida, Roberto Simoes, Carmo Borges, Ney Carter, Gomes Ferreira, Luis Gustavo, Stockins Fernandez, Benjamin Aleck Joseh, Montecinos, Humberto, Lanas, Fernando, Larico Gomez, Martin, Astudillo, Carlos, Conejeros, Carlos, Marin Cuevas, Patricio, Forero, Alejandro, Bugueno Gutierrez, Claudio, Aguilar, Juan, Potthoff Cardenas, Sergio, Eggers, German, Houzvic, Cesar, Rey, Carlos, Arriagada, German, Charme Vilches, Gustavo, Illescas Diaz, Jesus Jaime, Leal Cantu, Raul, Ramos Zavala, Maria Guadalupe, Cabrera Jardines, Ricardo, Espinola Zavaleta, Nilda, Lopez Rosas, Enrique, Llamas Esperon, Guillermo Antonio, Pozas, Gerardo, Cardona Munoz, Ernesto, Her-nandez, Norberto Matadamas, Leyva Rendon, Adolfo, Garcia Hernandez, Norberto, de los Rios Ibarra, Manuel, Virgen Carrillo, Luis Ramon, Lopez Villezca, David, Hernandez Herrera, Carlos, Lopez Prieto, Juan Jose, Gaona Rodriguez, Rodolfo, Villeda Espinosa, Efrain, Flores Martinez, David, Velasco Barcena, Jose, Fierro Fierro, Omar, Rodriguez Briones, Ignacio, Leiva Pons, Jose Luis, Alvarez Lopez, Humberto, Olvera Ruiz, Rafael, Cantu Brito, Carlos Gerardo, Chuquiure Valenzuela, Eduardo Julian Jose Roberto, Reyes Sanchez, Roxana, Bazzoni Ruiz, Alberto Esteban, Lopez Ruiz, Oscar Martin, Arriaga Nava, Roberto, Morales Cerda, Jesus David, Fajardo Campos, Pedro, Benavides Gonzalez, Mario, Lenz, Kurt, Hagn, Claus, Foechterle, Johannes, Drexel, Heinz, Huber, Kurt, Podczeck-Schweighofer, Andrea, Winkler, Michael, Schneeweiss, Bruno, Gegenhuber, Alfons, Lang, Wilfried, Eichinger-Hasenauer, Sabine, Kaserer, Peter, Sykora, Josef, Rasch, Heribert, Strohmer, Bernhard, Capiau, Luc, Vervoort, Geert, Wollaert, Bart, Hollanders, Geert, Vercammen, Jan, Balthazar, Yohan, Delforge, Marc, Xhaet, Olivier, Striekwold, Harry, Thoeng, John, Hermans, Kurt, Mairesse, Georges, Anne, Wim, Blankoff, Ivan, Beutels, Michel, Vandergoten, Peter, Purnode, Philippe, Godart, Pascal, Boussy, Tim, Desfontaines, Philippe, Heyse, Alex, Voet, Joeri, De Wolf, Axel, Zidkova, Eva, Spacek, Rudolf, Machova, Vilma, Ludka, Ondrej, Olsr, Josef, Kotik, Lubos, Racz, Blazej, Ferkl, Richard, Hubac, Jan, Kotik, Ilja, Monhart, Zdenek, Burianova, Hana, Jerabek, Ondrej, Pisova, Jana, Petrova, Iveta, Dedek, Vratislav, Honkova, Michaela, Podrazil, Petr, Reichert, Petr, Spinar, Jindrich, Novak, Miroslav, Durdil, Vaclav, Plocova, Katarina, Lastuvka, Jiri, Nielsen, Jorn, Hayashi, Yoshihito, Hirota, Shinichi, Abe, Yukihiko, Saito, Yoshihiro, Uchiyama, Hirohide, Takeda, Hiroshi, Ono, Hiroshi, Tohyo, Shuichi, Hanazono, Naoto, Miyajima, Seiichi, Shimono, Hisashi, Aoyama, Takuma, Shozawa, Yasunobu, Niijima, Yawara, Murai, Osamu, Inaba, Hideko, Nomura, Katsumasa, Nozoe, Masatsugu, Suzuki, Kazuo, Furukawa, Toshiyuki, Shiraiwa, Toshihiko, Ito, Nobuhisa, Nagai, Shunichi, Sato, Kiyoharu, Nakahara, Shiro, Shimoyama, Yujin, Ohara, Naoko, Kozuka, Teruhiko, Okita, Hideaki, Endo, Masato, Goto, Tsutomu, Hirose, Makoto, Nagata, Emiko, Nakanishi, Noriyuki, Mori, Toshizumi, Seki, Shuichi, Okamoto, Katsuhiro, Moriai, Osamu, Emura, Yoko, Fukuda, Tsuyoshi, Date, Haruhiko, Kawakami, Shuichi, Nagai, Sho, Ueyama, Yuya, Fudo, Tetsuro, Imaizumi, Mitsuru, Ogawa, Takuo, Take, Shunsuke, Ikeda, Hideo, Nishioka, Hiroaki, Sakamoto, Norihiko, Ikeoka, Kiyomitsu, Wakaki, Nobuo, Abe, Masatake, Doiuchi, Junji, Inagaki, Koichi, Iseki, Atsushi, Yoshida, Tomohiro, Goda, Toshihiro, Katsuki, Tsukasa, Sato, Atsushi, Mori, Etsuo, Tsubokura, Toshio, Shudo, Hiroshi, Fujimoto, Shunichi, Katsuya, Tomohiro, Furukawa, Yoshiyuki, Hosokawa, Hiroshi, Narumi, Jun, Yamamoto, Kiichiro, Owari, Masaki, Inakura, Takuya, Anno, Takafumi, Shirakawa, Kazuyuki, Ching, Chi Keong, Foo, David, Wong, Kelvin, Yuyang, Tan, Park, Hui Nam, Kim, Woo-Shik, Lee, HyeYoung, Jang, Sung-Won, Kim, Dae Hyeok, Kim, Jun, Ryu, DongRyeol, Shim, Jaemin, Kim, Dae-Kyeong, Choi, Dong Ju, Oh, Yong Seog, Cho, Myeong-Chan, Kim, Hack-Lyoung, Jeon, Hui-Kyung, Shin, Dong-Gu, Park, Sang Weon, Park, Hoon Ki, Han, Sang-Jin, Sung, Jung Hoon, Park, Hyung-Wook, Nam, Gi-Byoung, On, Young Keun, Lim, Hong Euy, Kwak, JaeJin, Cha, Tae-Joon, Hong, Taek Jong, Park, Seong Hoon, Yoon, Jung Han, Kim, Nam-Ho, Kim, Kee-Sik, Jung, Byung Chun, Hwang, Gyo-Seung, Kim, Chong-Jin, Rungaramsin, Sakda, Katekangplu, Peerapat, Khunrong, Porames, Bunyapipat, Thanita, Wongcharoen, Wanwarang, Kaewsuwanna, Pinij, Siriwattana, Khanchai, Tiyanon, Waraporn, Pattanaprichakul, Supalerk, Likittanasombat, Khanchit, Cholsaringkarl, Doungrat, Boonyapisit, Warangkana, Cheewatanakornkul, Sirichai, Silaruks, Songkwan, Hutayanon, Pisit, Chawanadelert, Seksan, Chattranukulchai, Pairoj, Chatlaong, Boonsert, Santanakorn, Yingsak, Kanokphatcharakun, Khompiya, Mongkolwongroj, Piya, Jai-Aue, Sasivimon, Komson, Ongkarn, Altun, Armagan, Aydinlar, Ali, Ongen, Zeki, Acikel, Sadik, Sahin, Durmus Yildiray, Yilmaz, Ozcan, Pekdemir, Hasan, Demir, Mesut, Sucu, Murat, Sahiner, Levent, Ersanli, Murat, Okuyan, Ertugrul, Aras, Dursun, Rolandi, Florencia, Cesar Ingaramo, Adrian, Alberto Sambadaro, Gustavo, Fernandez Caputi, Vanina, Luciardi, Hector, Graciela Berman, Sofia, Dragotto, Pablo, Poli, Daniela, Quintavalla, Roberto, Cosmi, Franco, Fanelli, Raffaele, Oriana, Vincenzo, Reggio, Raffaele, Anti, Roberto S., Pancaldi, Leonardo, De Cristofaro, Raimondo, Guazzaloca, Giuliana, De Blasio, Angelo, Uriate, Jorge Salerno, Lillo, Flavia, Pogliani, Enrico Maria, Javier Kleiban, Andres, Ahuad Guerrero, Rodolfo Andres, Adalberto Di Paola, Leonel, Dario Dran, Ricardo, Egido, Javier, Jose Fosco, Matias, Rodolfo Cartasegna, Luis, Gomez Vilamajo, Oscar, Luis Ramos, Jose, Sassone, Sonia, Zapata, Gerardo, Conde, Diego, Giacomi, Guillermo, Alfredo Fernandez, Alberto, Alberto Berli, Mario, Ferroni, Fabian, Sobral Filho, Dario Celestino, Jaber, Jefferson, Armaganijan, Luciana Vidal, Frack Costantini, Costantino Roberto, Steffens, Andre, Sebba Barroso de Souzaem, Weimar Kunz, de Souza Neto, Joao David, Ribeiro, Jose Marcio, Teixeira, Marcelo Silveira, Rossi, Paulo, Pires, Leonardo, Moreira, Daniel, Moura Jorge, Jose Carlos, Lorga Filho, Adalberto Menezes, Bodanese, Luiz, Montera, Marcelo Westerlund, Del Carlo, Carlos Henrique, Saad, Jamil Abdalla, Alves Costa, Fernando Augusto, Lopes, Renato, de Aranjo, Gilson Roberto, Manenti, Euler Roberto, Kerr Saraiva, Jose Francisco, Ferreira Braga, Joao Carlos, Negri, Alexandre, Moncada, Carlos, Precoma, Dalton, Roquette, Fernando, Reis, Gilmar, Ramos Filho, Roberto Alvaro, Figueiredo, Estevao Lanna, Botelho, Roberto Vieira, Fontoura Tavares, Claudio Munhoz, Finimundi, Helius Carlos, Kochi, Adriano, Broilo Franca, Cesar Cassio, Alban, Fabio, Aranha Rosito, Guido Bernardo, de Moura Xavier Moraes Junior, Joao Batista, Husted, Steen, Hintze, Ulrik, Rasmussen, Soren, Sygehus, Nwstved, Bremmelgaard, Arne, Markenvard, John, Borger, Jan, Solgaard, Jorgen, Eriksen, Ebbe, Lokkegaard, Thomas, Bruun, Michael, Mertz, Jacob, Schou, Morten, Olsen, Michael, Viitanen, Carmela, Paganelli, Franck, Ohayon, Joel, Casassus, Frederic, Galinier, Michel, Gottwalles, Yannick, Loiselet, Philippe, Koujan, Mohamed Bassel, Destrac, Sylvain, Piot, Olivier, Cebron, Jean-Pierre, Guenoun, Maxime, Guedj-Meynier, Dominique, Lokesh, A. G., Zuber, Mathieu, Amarenco, Pierre, Ellie, Emmanuel, Kadouch, James, Huberman, Jean-Pierre, Lemaire, Nestor, Rodier, Gilles, Vandamme, Xavier, Sibon, Igor, Neau, Jean-Philippe, Mahagne, Marie Helene, Mielot, Antoine, Bonnefoy, Marc, Churet, Jean-Baptiste, Navarre, Vincent, Sellem, Frederic, Monniot, Gilles, Boyes, Jean-Paul, Doucet, Bernard, Martelet, Michel, Obadia, Desire, Crousillat, Bernard, Mouallem, Joseph, Bearez, Etienne, Brugnaux, Jean Philippe, Fedorowsky, Alain, Nazeyrollas, Pierre, Berneau, Jean-Baptiste, Chemin, Frederic, Schellong, Sebastien, Koeniger, Georg, Kopf, Andreas, Gerbaulet, Uwe, Kellner, Bernd-Thomas, Schaefer, Thomas, Purr, Jan, Eissfeller, Enno, Zauzig, Heinz-Dieter, Riegel, Peter, Axthelm, Christoph, Heinz, Gerd-Ulrich, Pustelnik, Andreas, Zutz, Stefan, Eder, Wolfgang, Rehling, Guenter, Glatzel, Dirk, Ludwig, Norbert, Sandow, Petra, Wiswedel, Henning, Wildenauer, Cosmas, Schoen, Steffen, Schwarz, Toralf, Babyesiza, Adyeri, Kropp, Maximilian, Zimny, Hans-Hermann, Kahl, Friedhelm, Caspar, Andreas, Omankowsky, Sabine, Laessig, Torsten, Hartmann, Hermann-Josef, Lehmann, Gunter, Bindig, Hans-Walter, Hergdt, Gunter, Reimer, Dietrich, Hauk, Joachim, Michel, Holger, Dres, Praxis, Erdle, Werner, Dorsch, Wilfried, Dshabrailov, Janna, Rapp, Karl-Albrecht, Epelde Gonzalo, Francisco, Almeida Fernandez, Carlos Alexandre, Martinez Navarro, Encarnacion, Montero Alia, Juan Jose, Barreda Gonzalez, Maria, Moleiro Oliva, Maria Angels, Iglesias Sanmartin, Jose, Rodriguez Alvarez, Maria del Mar, Ripoll Vera, Tomas, Jimenez Navarro, Manuel, Vazquez Caamano, Maria, Arcocha Tones, Maria Fe, Marcos Gomez, Gonzalo, Iniguez Romo, Andres, Prieto Diaz, Miguel Angel, Wirdby, Alexander, Linden, Jan, and Henriksson, Kerstin

Subjects
Male, medicine.medical_specialty, Acute coronary syndrome, Vascular damage Radboud Institute for Health Sciences [Radboudumc 16], Hemorrhage, 030204 cardiovascular system & hematology, antiplatelet therapy, Coronary artery disease, Anticoagulation, 03 medical and health sciences, 0302 clinical medicine, Risk Factors, Cause of Death, Internal medicine, Atrial Fibrillation, medicine, Humans, 030212 general & internal medicine, Acute Coronary Syndrome, bleeding, mortality, stroke, Stroke, Aged, Proportional Hazards Models, business.industry, Hazard ratio, Anticoagulants, Atrial fibrillation, General Medicine, Prognosis, medicine.disease, Blood pressure, Cardiovascular Diseases, Heart failure, Cardiology, Female, Liver function, business, Platelet Aggregation Inhibitors, Follow-Up Studies
Abstract

Item does not contain fulltext BACKGROUND: Many patients with atrial fibrillation have concomitant coronary artery disease with or without acute coronary syndromes and are in need of additional antithrombotic therapy. There are few data on the long-term clinical outcome of atrial fibrillation patients with a history of acute coronary syndrome. This is a 2-year study of atrial fibrillation patients with or without a history of acute coronary syndromes. METHODS: Adults with newly diagnosed atrial fibrillation and >/=1 investigator-defined stroke risk factor were enrolled in GARFIELD-AF between March 2010 and September 2015. The association between prior acute coronary syndromes and long-term outcomes was determined using a Cox proportional hazards model, adjusting for baseline risk factors, oral anticoagulation (OAC) +/- antiplatelet (AP) therapy, and usual care. RESULTS: Of 39,679 patients, 10.5% had a history of acute coronary syndromes. At 2-year follow-up, patients with prior acute coronary syndromes had higher adjusted risks of stroke/systemic embolism (hazard ratio [HR] 1.39; 95% confidence interval [CI], 1.08-1.78), major bleeding (HR 1.30; 95% CI, 0.95 -1.79), all-cause mortality (HR 1.34; 95% CI, 1.21 -1.49), cardiovascular mortality (HR 1.85; 95% CI, 1.51-2.26), and new acute coronary syndromes (HR 3.42; 95% CI, 2.62-4.45). Comparing antithrombotic therapy in the acute coronary syndromes vs no acute coronary syndromes groups, most patients received OAC +/- AP: 60.8% vs 66.1%, but AP therapy was more likely in the acute coronary syndromes group (68.1% vs 32.9%), either alone (34.9% vs 20.8%) or with OAC (33.2% vs 12.1%). Overall, 17.8% in the acute coronary syndromes group received dual AP therapy with (5.3%) or without OAC (12.5%). Among patients with moderate/high risk for stroke/systemic embolism, fewer in the acute coronary syndromes group received OAC with or without AP therapy (Congestive heart failure, Hypertension, Age 75 years, Diabetes mellitus, prior Stroke, TIA, or thromboembolism, Vascular disease, Age 65-74 years, Sex category [CHA2DS2-VASc] 2: 52.1% vs 64.6%; CHA2DS2-VASc >/=3: 62.0% vs 70.7%), and the majority with a Hypertension (uncontrolled systolic blood pressure >160 mm Hg), Abnormal renal or liver function, previous Stroke, Bleeding history or predisposition, Labile international normalized ratios, Elderly, and concomitant Drugs or alcohol excess (HAS-BLED) score >/=3 were on AP therapy (83.8% vs 65.5%). CONCLUSIONS: In GARFIELD-AF, previous acute coronary syndromes are associated with worse 2-year outcomes and a greater likelihood of under-treatment with OAC, while two-thirds of patients receive AP therapy. Major bleeding was more common with previous acute coronary syndromes, even after adjusting for all risk factors.

Published
2019
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77. Long-term outcome of cervical artery dissection : IPSYS CeAD: study protocol, rationale, and baseline data of an Italian multicenter research collaboration.

Author

Bonacina, Sonia, Grassi, Mario, Zedde, Marialuisa, Zini, Andrea, Bersano, Anna, Gandolfo, Carlo, Silvestrelli, Giorgio, Baracchini, Claudio, Cerrato, Paolo, Lodigiani, Corrado, Marcheselli, Simona, Paciaroni, Maurizio, Rasura, Maurizia, Cappellari, Manuel, Del Sette, Massimo, Cavallini, Anna, Morotti, Andrea, Micieli, Giuseppe, Lotti, Enrico Maria, and DeLodovici, Maria Luisa

Subjects
TRANSIENT ischemic attack, CEREBRAL ischemia, CAROTID artery dissections, ARTERIES, STROKE treatment, RESEARCH, STROKE, MEDICAL cooperation, HUMAN dissection, RESEARCH funding, VERTEBRAL artery dissections, VETERINARY dissection, LONGITUDINAL method
Abstract

Long-term consequences of cervical artery dissection (CeAD), a major cause of ischemic stroke in young people, have been poorly investigated. The Italian Project on Stroke at Young Age - Cervical Artery Dissection (IPSYS CeAD) project is a multicenter, hospital-based, consecutively recruiting, observational, cohort study aimed to address clinically important questions about long-term outcome of CeAD patients, which are not covered by other large-scale registries. Patients with radiologically diagnosed CeAD were consecutively included in the registry. Baseline demographic and clinical variables, as well as information on risk factors, were systematically collected for each eligible patient. Follow-up evaluations were conducted between 3 and 6 months after the initial event (t1) and then annually (t2 at 1 year, t3 at 2 years , and so on), in order to assess outcome events (long-term recurrent CeAD, any fatal/nonfatal ischemic stroke, transient ischemic attack (TIA), or other arterial thrombotic event, and death from any cause). Between 2000 and 2019, data from 1530 patients (age at diagnosis, 47.2 ± 11.5 years; women, 660 [43.1%]) have been collected at 39 Italian neurological centers. Dissection involved a single vessel in 1308 (85.5%) cases and caused brain ischemia in 1303 (85.1%) (190 TIA/1113 ischemic stroke). Longitudinal data are available for 1414 (92.4%) patients (median follow-up time in patients who did not experience recurrent events, 36.0 months [25th to 75th percentile, 63.0]). The collaborative IPSYS CeAD effort will provide novel information on the long-term outcome of CeAD patients. This could allow for tailored treatment approaches based on patients' individual characteristics. [ABSTRACT FROM AUTHOR]

Published
2020
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79. In vitro Fertilization Procedures with Embryo Transfer and Their Association with Thrombophilia, Thrombosis and Early Antithrombotic Treatments.

Author

Micco, Pierpaolo Di, Russo, Vincenzo, Mastroiacovo, Daniela, Bosevski, Marijan, and Lodigiani, Corrado

Subjects
EMBRYO transfer, FERTILIZATION in vitro, HYPERCOAGULATION disorders, INDUCED ovulation, THROMBOSIS, DRUG administration
Abstract

In vitro fertilization (IVF) procedures have been frequently associated with antithrombotic treatments, in particular, to aspirin or low-molecular-weight heparin (LMWH). The rationale of this treatment is based on the increase of thrombotic risk occurring in this clinical context. Indeed, both prothrombotic changes of coagulation parameters specifically related to IVF procedures as well as the presence of potential thrombophilic alterations may concur to increase the risk in these women. Furthermore, the presence of thrombophilia has been suggested as a potential cause of recurrent IVF failures. Therefore, antithrombotic treatments have been historically planned to prevent thrombotic disorders during pharmacological ovarian stimulation and/or to increase a successful rate of pregnancy and live births after IVF with embryo transfer. However, up to date, the role of inherited and|or acquired thrombophilia is still debated as well as a univocal therapeutic approach is lacking in women with infertility. The administration of antithrombotic drugs differs in several studies and even the dosages of aspirin and|or low-molecular-weight heparin are different. This review focuses on underlining current evidence on the role of thrombophilia and thromboprophylaxis in women selected for IVF with embryo transfer. [ABSTRACT FROM AUTHOR]

Published
2020
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80. Pathologic up-regulation of TNFSF15–TNFRSF25 axis sustains endothelial dysfunction in unprovoked venous thromboembolism.

Author

Bella, Silvia Della, Calcaterra, Francesca, Bacci, Monica, Carenza, Claudia, Pandolfo, Chiara, Ferrazzi, Paola, Uva, Paolo, Pagani, Massimiliano, Lodigiani, Corrado, and Mavilio, Domenico

Subjects
ENDOTHELIUM diseases, THROMBOEMBOLISM, ENDOTHELIAL cells, PATHOLOGY, MICROARRAY technology, HEART function tests
Abstract

Aims The pathogenetic mechanisms underlying unprovoked venous thromboembolism (uVTE) are largely unknown. In this study, we investigated the molecular mechanisms involved in uVTE pathogenesis by using ex vivo expanded endothelial colony-forming cells (ECFCs), which represent a valuable non-invasive tool for the assessment of endothelial function. Methods and results We isolated and expanded ECFCs from the peripheral blood of uVTE patients and observed that these cells underwent earlier senescence and showed lower growth rate compared with ECFCs obtained from healthy donors. Through microarray expression profiling, we demonstrated that 2905 genes were differentially expressed between patients and controls. Among them, the anti-angiogenic cytokine TNF superfamily member 15 (TNFSF15) and its death-receptor TNFRSF25 were up-regulated in uVTE ECFCs, and this finding was validated by RT-qPCR. TNFSF15 up-regulation was confirmed at the protein level in ECFC supernatants, and the in vivo relevance of these findings was further corroborated by demonstrating that also the plasmatic levels of TNFSF15 are increased in uVTE patients. After proving that exogenous TNFSF15 exerts pro-apoptotic and anti-proliferative activity on control ECFCs, we demonstrated through blocking experiments that TNFSF15 up-regulation contributes to impaired survival and proliferation of uVTE ECFCs. Conclusion By providing evidence that TNFSF15 impairs ECFC functions crucial to endothelial repair, and that uVTE patients have increased TNFSF15 levels both ex vivo and in vivo , the results of this study suggest that pathologic up-regulation of TNFSF15–TNFRSF25 axis may contribute to uVTE pathogenesis, and may represent the target for novel therapeutic strategies aimed at preventing recurrences in uVTE patients. [ABSTRACT FROM AUTHOR]

Published
2020
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81. Idiopathic Hypereosinophilia and Venous Thromboembolism: Is There a Pathophysiological or Clinical Link? Description of an Intriguing Clinical Case.

Author

Micco, Pierpaolo Di, Scudiero, Olga, scudiero, olga, Lombardo, Barbara, and Lodigiani, Corrado

Subjects
THROMBOEMBOLISM, VENOUS thrombosis, HORMONE therapy, THROMBOSIS, ACTIVATED protein C resistance, PAROXYSMAL hemoglobinuria
Abstract

Thrombosis events usually occur after prolonged bedrest, pregnancy, hormonal therapy, recent surgery and in the presence of inherited or acquired thrombophilia. However, several other diseases are often associated with thrombosis although their frequency is not easily estimated. Eosinophilia is one of these conditions. From a clinical viewpoint it is very difficult to understand which conditions might lead to a thrombotic event because the underlying pathophysiological mechanisms are different. Here, we report a case of idiopathic hypereosinophilia associated to venous thromboembolism without any other associated prothrombotic condition. [ABSTRACT FROM AUTHOR]

Published
2020
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82. Risk of reoperation in bioprosthetic valve patients with indication for long-term anticoagulation. Results from the observational retrospective multicentre PLECTRUM study

Author

Poli, Daniela, primary, Antonucci, Emilia, additional, Pengo, Vittorio, additional, Grifoni, Elisa, additional, Maggini, Niccolò, additional, Testa, Sophie, additional, Lodigiani, Corrado, additional, Insana, Antonio, additional, Marongiu, Francesco, additional, Barcellona, Doris, additional, Paparo, Carmelo, additional, Bucherini, Eugenio, additional, Pignatelli, Pasquale, additional, and Palareti, Gualtiero, additional

Published
2018
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83. Activated prothrombin complex concentrate (FEIBA® ) in acquired haemophilia A: a large multicentre Italian study - the FAIR Registry

Author

Zanon, Ezio, primary, Pasca, Samantha, additional, Santoro, Cristina, additional, Gamba, Gabriella, additional, Siragusa, Sergio M., additional, Rocino, Angiola, additional, Cantori, Isabella, additional, Federici, Augusto B., additional, Mameli, Luciana, additional, Giuffrida, Gaetano, additional, Falanga, Anna, additional, Lodigiani, Corrado, additional, Santoro, Rita C., additional, Milan, Marta, additional, Ambaglio, Chiara, additional, Napolitano, Mariasanta, additional, and Mazzucconi, Maria G., additional

Published
2018
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84. Direct Oral Anticoagulants in Addition to Antiplatelet Therapy for Secondary Prevention After Acute Coronary Syndromes

Author

Chiarito, Mauro, primary, Cao, Davide, additional, Cannata, Francesco, additional, Godino, Cosmo, additional, Lodigiani, Corrado, additional, Ferrante, Giuseppe, additional, Lopes, Renato D., additional, Alexander, John H., additional, Reimers, Bernhard, additional, Condorelli, Gianluigi, additional, and Stefanini, Giulio G., additional

Published
2018
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89. The effect of parnaparin sodium on in vitro fertilization outcome: A prospective randomized controlled trial

Author

Lodigiani, Corrado, primary, Dentali, Francesco, additional, Banfi, Elena, additional, Ferrazzi, Paola, additional, Librè, Luca, additional, Quaglia, Ilaria, additional, Cafaro, Luca, additional, Morenghi, Emanuela, additional, Pacetti, Veronica, additional, Zannoni, Elena, additional, Baggiani, Anna Maria, additional, and Levi-Setti, Paolo Emanuele, additional

Published
2017
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90. Migraine and Cryptogenic Ischemic Stroke.

Author

Mazzoleni, Valentina, Grassi, Mario, Lodigiani, Corrado, Rasura, Maurizia, Zedde, Marialuisa, Gandolfo, Carlo, Zini, Andrea, DeLodovici, Maria Luisa, Paciaroni, Maurizio, Del Sette, Massimo, Toriello, Antonella, Musolino, Rossella, Calabrò, Rocco Salvatore, Bovi, Paolo, Giossi, Alessia, Adami, Alessandro, Silvestrelli, Giorgio, Cavallini, Anna, Marcheselli, Simona, and Bonifati, Domenico Marco

Subjects
MIGRAINE aura, MIGRAINE, TRANSCRANIAL Doppler ultrasonography, ISCHEMIC stroke, CEREBRAL infarction
Abstract

The available evidence on the relationship between migraine and cryptogenic ischemic stroke (CIS) is scarce. Thirty-six cases had missing data in the variable "any migraine"; 70 participants (58 cases and 12 control subjects) had missing data in the variables "migraine without aura" and "migraine with aura.". [Extracted from the article]

Published
2021
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91. Propensity Score–Based Analysis of Percutaneous Closure Versus Medical Therapy in Patients With Cryptogenic Stroke and Patent Foramen Ovale

Author

Pezzini, Alessandro, primary, Grassi, Mario, additional, Lodigiani, Corrado, additional, Patella, Rosalba, additional, Gandolfo, Carlo, additional, Zini, Andrea, additional, DeLodovici, Maria Luisa, additional, Paciaroni, Maurizio, additional, Del Sette, Massimo, additional, Toriello, Antonella, additional, Musolino, Rossella, additional, Calabrò, Rocco Salvatore, additional, Bovi, Paolo, additional, Adami, Alessandro, additional, Silvestrelli, Giorgio, additional, Sessa, Maria, additional, Cavallini, Anna, additional, Marcheselli, Simona, additional, Marco Bonifati, Domenico, additional, Checcarelli, Nicoletta, additional, Tancredi, Lucia, additional, Chiti, Alberto, additional, Del Zotto, Elisabetta, additional, Tomelleri, Giampaolo, additional, Spalloni, Alessandra, additional, Giorli, Elisa, additional, Costa, Paolo, additional, Giacalone, Giacomo, additional, Ferrazzi, Paola, additional, Poli, Loris, additional, Morotti, Andrea, additional, Piras, Valeria, additional, Rasura, Maurizia, additional, Simone, Anna Maria, additional, Gamba, Massimo, additional, Cerrato, Paolo, additional, Zedde, Maria Luisa, additional, Micieli, Giuseppe, additional, Melis, Maurizio, additional, Massucco, Davide, additional, Guido, Davide, additional, De Giuli, Valeria, additional, Bonaiti, Silvia, additional, D’Amore, Cataldo, additional, La Starza, Sara, additional, Iacoviello, Licia, additional, and Padovani, Alessandro, additional

Published
2016
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92. Serum cholesterol levels, HMG-CoA reductase inhibitors and the risk of intracerebral haemorrhage. The Multicenter Study on Cerebral Haemorrhage in Italy (MUCH-Italy)

Author

Pezzini, Alessandro, primary, Grassi, Mario, additional, Iacoviello, Licia, additional, Zedde, Marialuisa, additional, Marcheselli, Simona, additional, Silvestrelli, Giorgio, additional, DeLodovici, Maria Luisa, additional, Sessa, Maria, additional, Zini, Andrea, additional, Paciaroni, Maurizio, additional, Azzini, Cristiano, additional, Gamba, Massimo, additional, Del Sette, Massimo, additional, Toriello, Antonella, additional, Gandolfo, Carlo, additional, Bonifati, Domenico Marco, additional, Tassi, Rossana, additional, Cavallini, Anna, additional, Chiti, Alberto, additional, Calabrò, Rocco Salvatore, additional, Musolino, Rossella, additional, Bovi, Paolo, additional, Tomelleri, Giampaolo, additional, Di Castelnuovo, Augusto, additional, Vandelli, Laura, additional, Ritelli, Marco, additional, Agnelli, Giancarlo, additional, De Vito, Alessandro, additional, Pugliese, Nicola, additional, Martini, Giuseppe, additional, Lanari, Alessia, additional, Ciccone, Alfonso, additional, Lodigiani, Corrado, additional, Malferrari, Giovanni, additional, Del Zotto, Elisabetta, additional, Morotti, Andrea, additional, Costa, Paolo, additional, Poli, Loris, additional, De Giuli, Valeria, additional, Bonaiti, Silvia, additional, La Spina, Paolo, additional, Marcello, Norina, additional, Micieli, Giuseppe, additional, de Gaetano, Giovanni, additional, Colombi, Marina, additional, and Padovani, Alessandro, additional

Published
2016
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95. Anticoagulants Resumption after Warfarin-Related Intracerebral Haemorrhage: The Multicenter Study on Cerebral Hemorrhage in Italy (MUCH-Italy).

Author

Poli, Loris, Grassi, Mario, Zedde, Marialuisa, Marcheselli, Simona, Silvestrelli, Giorgio, Sessa, Maria, Zini, Andrea, Paciaroni, Maurizio, Azzini, Cristiano, Gamba, Massimo, Toriello, Antonella, Tassi, Rossana, Giorli, Elisa, Calabrò, Rocco Salvatore, Ritelli, Marco, De Vito, Alessandro, Pugliese, Nicola, Martini, Giuseppe, Lanari, Alessia, and Lodigiani, Corrado

Published
2018
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96. Rate and duration of hospitalization for deep vein thrombosis and pulmonary embolism in real-world clinical practice

Author

Dentali, Francesco, primary, Di Micco, Gianluca, additional, Giorgi Pierfranceschi, Matteo, additional, Gussoni, Gualberto, additional, Barillari, Giovanni, additional, Amitrano, Maria, additional, Fontanella, Andrea, additional, Lodigiani, Corrado, additional, Guida, Anna, additional, Visonà, Adriana, additional, Monreal, Manuel, additional, and Di Micco, Pierpaolo, additional

Published
2015
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97. Determinants of premature familial arterial thrombosis in patients with juvenile ischaemic stroke

Author

Pezzini, Alessandro, primary, Grassi, Mario, primary, Lodigiani, Corrado, primary, Patella, Rosalba, primary, Gandolfo, Carlo, primary, Zini, Andrea, primary, DeLodovici, Maria Luisa, primary, Paciaroni, Maurizio, primary, Del Sette, Massimo, primary, Toriello, Antonella, primary, Musolino, Rossella, primary, Calabrò, Rocco Salvatore, primary, Bovil, Paolo, primary, Adami, Alessandro, primary, Silvestrelli, Giorgio, primary, Sessa, Maria, primary, Cavallini, Anna, primary, Marcheselli, Simona, primary, Bonifati, Domenico Marco, primary, Checcarelli, Nicoletta, primary, Tancredi, Lucia, primary, Chiti, Alberto, primary, Del Zotto, Elisabetta, primary, Spalloni, Alessandra, primary, Costa, Paolo, primary, Giacalone, Giacomo, primary, Ferrazzi, Paola, primary, Poli, Loris, primary, Andrea, Morotti, primary, Maurizia, Rasura, primary, Simone, Anna Maria, primary, Gamba, Massimo, primary, Cerrato, Paolo, primary, Micieli, Giuseppe, primary, Melis, Maurizio, primary, Massucco, Davide, primary, De Giuli, Valeria, primary, Pepe, Daniele, primary, Iacoviello, Licia, primary, and Padovani, Alessandro, additional

Published
2015
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98. Association Between Migraine and Cervical Artery Dissection: The Italian Project on Stroke in Young Adults.

Author

De Giuli, Valeria, Grassi, Mario, Lodigiani, Corrado, Patella, Rosalba, Zedde, Marialuisa, Gandolfo, Carlo, Zini, Andrea, DeLodovici, Maria Luisa, Paciaroni, Maurizio, Del Sette, Massimo, Azzini, Cristiano, Toriello, Antonella, Musolino, Rossella, Salvatore Calabrò, Rocco, Bovi, Paolo, Sessa, Maria, Adami, Alessandro, Silvestrelli, Giorgio, Cavallini, Anna, and Marcheselli, Simona

Published
2017
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99. Activated prothrombin complex concentrate (FEIBA®) in acquired haemophilia A: a large multicentre Italian study – the FAIR Registry.

Author

Zanon, Ezio, Pasca, Samantha, Santoro, Cristina, Gamba, Gabriella, Siragusa, Sergio M., Rocino, Angiola, Cantori, Isabella, Federici, Augusto B., Mameli, Luciana, Giuffrida, Gaetano, Falanga, Anna, Lodigiani, Corrado, Santoro, Rita C., Milan, Marta, Ambaglio, Chiara, Napolitano, Mariasanta, and Mazzucconi, Maria G.

Abstract

The article presents a study which aimed to assess dosage, duration of treatment, as well as the effectiveness and safety of activated prothrombin complex concentrate (aPCC) in patients with Acquired haemophilia A (AHA), a rare bleeding disorder caused by the spontaneous development of auto-antibodies against coagulation factor VIII. Statistical analysis showed results that may be useful in clinical practice, but controlled trials needed to confirm the data obtained.

Published
2019
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100. Predictors of Long-Term Recurrent Vascular Events After Ischemic Stroke at Young Age

Author

Pezzini, Alessandro, primary, Grassi, Mario, additional, Lodigiani, Corrado, additional, Patella, Rosalba, additional, Gandolfo, Carlo, additional, Zini, Andrea, additional, DeLodovici, Maria Luisa, additional, Paciaroni, Maurizio, additional, Del Sette, Massimo, additional, Toriello, Antonella, additional, Musolino, Rossella, additional, Calabrò, Rocco Salvatore, additional, Bovi, Paolo, additional, Adami, Alessandro, additional, Silvestrelli, Giorgio, additional, Sessa, Maria, additional, Cavallini, Anna, additional, Marcheselli, Simona, additional, Bonifati, Domenico Marco, additional, Checcarelli, Nicoletta, additional, Tancredi, Lucia, additional, Chiti, Alberto, additional, Del Zotto, Elisabetta, additional, Spalloni, Alessandra, additional, Giossi, Alessia, additional, Volonghi, Irene, additional, Costa, Paolo, additional, Giacalone, Giacomo, additional, Ferrazzi, Paola, additional, Poli, Loris, additional, Morotti, Andrea, additional, Rasura, Maurizia, additional, Simone, Anna Maria, additional, Gamba, Massimo, additional, Cerrato, Paolo, additional, Micieli, Giuseppe, additional, Melis, Maurizio, additional, Massucco, Davide, additional, De Giuli, Valeria, additional, Iacoviello, Licia, additional, and Padovani, Alessandro, additional

Published
2014
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