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64. Taming Distrust in the Decentralized Internet with PIXIU

Author

Xia, Yubin, Liu, Qingyuan, Tan, Cheng, Leng, Jing, Xu, Shangning, Zang, Binyu, and Chen, Haibo

Subjects
Computer Science - Cryptography and Security
Abstract

Decentralized Internet is booming. People are fascinated by its promise that users can truly own their data. However, in a decentralized Internet, completing a task usually involves multiple nodes with mutual distrust. Such distrust might eventually become a major obstacle for the growth of the decentralized Internet. In this paper, we analyze the distrust using a simple model and highlight the properties required to faithfully accomplish one task in a decentralized Internet. We also introduce our draft solution -- PIXIU, a framework to mitigate the distrust among different nodes. In PIXIU, we design and utilize trust-{\lambda} and decentralized executor to achieve the above-needed properties.

Published
2019

75. Development and validation of a score for clinical deterioration in patients with cerebral venous thrombosis.

Author

Feng, Yinghe, Mo, Shaohua, Li, Xiong, Jiang, Pengjun, Wu, Jun, Li, Jiangan, Liu, Peng, Wang, Shuo, Liu, Qingyuan, and Tong, Xianzeng

Subjects
RECEIVER operating characteristic curves, CLINICAL deterioration, CEREBRAL embolism & thrombosis, VENOUS thrombosis, GLASGOW Coma Scale
Abstract

Patients with cerebral venous thrombosis (CVT) may experience poor response to anticoagulant therapy and delayed surgical treatment may lead to clinical deterioration. However, the factors contributing to clinical deterioration remain poorly understood. Patients with CVT from three centers between January 2017 and October 2023 were included and grouped as the development cohort and validation cohort. The danger triangle was defined as the posterior two-thirds of the superior sagittal sinus, confluence of sinuses, straight sinus, and deep venous system. The primary endpoint was clinical deterioration, characterized by new or progressive bleeding or infarctions or worsened neurological conditions post-admission. Using the results of multivariable logistic analysis, the Cerebral venOus thrombosis DEterioration (CODE) score was developed within the development cohort and validated within the validation cohort. The score' performance in predicting clinical deterioration was evaluated using the area under the receiver operating characteristic curve (AUC). The development cohort included 194 CVT patients (101 males, and the median age was 38 years). clinical deterioration occurred in 45 (23.2%) patients. Multivariate logistic analysis defined D-dimer > 1.5 mg/L, Glasgow coma scale ≤ 8, intracerebral hemorrhage, danger triangle as risk factors of clinical deterioration. The CODE score integrating these factors performed well to predict patients suffering from clinical deterioration within the validation cohort (n = 79, 11 deteriorations) with an AUC of 0.83 (95%CI, 0.71–0.96) and an accuracy of 88.6% (95%CI, 81.4–95.8%). CODE score could evaluate the risk of clinical deterioration in CVT patients and may serve as a useful tool for decision-making for CVT. Clinical Deterioration in Cerebral Venous Thrombosis: A Predictive Study (CVT deterioration cohort), ClinicalTrials.gov number: NCT06266585, link: https://classic.clinicaltrials.gov/ct2/show/NCT06266585) [ABSTRACT FROM AUTHOR]

Published
2025
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77. Pre-lithiation carbon anodes mitigating potassium loss for high-performance potassium-ion energy storage devices.

Author

Du, Danni, Liu, Qingyuan, Gao, Jing, Qin, Yuying, Jiang, Xiaobo, Shi, Yuanchang, Hua, Minghao, Lin, Xiaohang, Zhang, Zhiwei, Wang, Chengxiang, Yin, Longwei, and Wang, Rutao

Abstract

Pre-potassiation technologies, which serve to provide additional potassium sources and/or mitigate potassium loss during cycling, are capable of enhancing the energy density and cycling life of potassium-ion capacitors (PICs) and potassium-ion batteries (PIBs). However, many reported pre-potassiation strategies involve using highly chemically reactive potassium sources, such as metallic potassium or K-containing additives, which increase both the cost and production risks. Herein, we propose a novel potassium-ion compensation strategy to meet the demand for high-performance potassium-ion full cells without using any high chemical reactivity potassium sources. This strategy is based on the foundation that a pre-lithiation carbon anode with a preformed solid-electrolyte-interphase (SEI) layer can effectively mitigate potassium loss without hindering the K+ diffusion from the electrolyte to the electrode during cell operation. PICs based on pre-lithiation carbon anodes, including soft carbon, hard carbon, and graphite, show better capacitive performance than those based on pre-potassiation carbon counterparts. This versatile strategy is also applicable to high-performance PIBs. We believe that this design principle, which incorporates mature pre-lithiation technologies into potassium-ion energy storage systems, has the potential to resolve some of the challenges with immature pre-potassium technologies. [ABSTRACT FROM AUTHOR]

Published
2024
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