Search

Your search keyword '"Linolenic acids -- Physiological aspects"' showing total 88 results
Start Over Descriptor "Linolenic acids -- Physiological aspects"
88 results on '"Linolenic acids -- Physiological aspects"'

51. Dietary intakes of (n-3) polyunsaturated fatty acids and their interactions with antioxidant vitamin E in relation to the risk of breast cancer: the E3N-EPIC cohort study

Author

Thiebaut, Anne C.M., Chajes, Veronique, Gerber, Mariette, Berrino, Franco, Riboli, Elio, Benichou, Jacques, and Clavel-Chapelon, Francoise

Subjects
Unsaturated fatty acids -- Physiological aspects, Linolenic acids -- Physiological aspects, Vitamin E -- Physiological aspects, Breast cancer -- Research, Breast cancer -- Prevention, Breast cancer -- Nutritional aspects, Food/cooking/nutrition
Abstract

BACKGROUND: Experimental studies suggest beneficial effects on mammary carcinogenesis of (n-3) PUFAs, possibly in interaction with antioxidants. However, epidemiological studies have been inconsistent, and few have assessed combined effects of (n-3) PUFA and antioxidant intakes on breast cancer risk. OBJECTIVE: The objectives of this study were to examine the association between (n-3) PUFA intakes and breast cancer risk and to evaluate effect modifications by vitamin E intakes. DESIGN: The study population included 67,629 women from the French E3N-EPIC cohort, aged 41 to 71 y, who completed a diet history questionnaire in 1993. For an average follow-up of 8.0 y, 2054 incident cases of invasive breast cancer were recorded. RESULTS: Overall, breast cancer risk was not related to individual (n-3) PUFA intakes. However, breast cancer risk was decreased with increasing intakes of [alpha]-linolenic acid [18:3 (n-3)] originating from vegetable sources [highest versus lowest quintile, hazard ratio (HR) = 0.82; 95% CI: 0.71, 0.95; [P.sub.trend] = 0.009] and increased with increasing intakes of [alpha]-linolenic acid from nuts ([P.sub.trend] = 0.031). Long-chain (n-3) PUFA intakes were positively associated with breast cancer risk in the lowest quintile of dietary vitamin E intake (HR = 1.65; 95% CI: 1.18, 6.09; [P.sub.trend] = 0.036). Conversely, in the highest quintile of vitamin E intake, HRs related to increasing quintiles of long-chain (n-3) PUFA intake were all below unity but not significantly so. CONCLUSIONS: These data suggest that the effect of [alpha]-linolenic acid intake on breast cancer risk may differ according to food sources, either reflecting different food patterns or different a.linolenic acid isomers. They also suggest that supplementation with (n-3) PUFAs should be counterbalanced by appropriate dietary antioxidant intakes to avoid carcinogenic effects. However, this study provides no support that vitamin E as a supplement may reduce breast cancer risk.

Published
2005

52. Different effects of peroxidized (n-3) and (n-6) fatty acids on cultured colon cells

Author

Udilova, N., Jurek, D., Stolze, K., Schulte-Hermann, R., Nohl, H., and Marian, B.

Subjects
Dietary fat -- Composition, Dietary fat -- Physiological aspects, Linolenic acids -- Physiological aspects, Lipid peroxidation -- Physiological aspects, Food/cooking/nutrition
Abstract

A fat-rich diet is a major risk factor in colon carcinogenesis, although the molecular mechanisms are not fully understood. The composition of fat, especially the ratio of (n-3) to (n-6) fatty acids, seems to modulate the risk of colon cancer. Dietary polyunsaturated fatty acids (PUFA) may be readily oxidized to the respective hydroperoxides when heated or exposed to light and oxygen in air. In the presence of transition metals, lipid hydroperoxides yield lipid-derived radicals than can be detected by spin-trapping electron spin resonance. These radicals initiate lipid peroxidation in the cell membrane, resulting in toxic effects. We compared the effect of lipid hydroperoxides from (n-3) and (n-6) fatty acids (linolenic and linoleic acid, respectively) on proliferation of cultured colon carcinoma cells (SW480), colon adenoma cells (LT97) and intestinal epithelial cells (IEC18). Both peroxidized linoleic and linolenic acids were found to be toxic in all cultured cells under investigation. However, peroxidized linolenic acid was most toxic to SW480 cells followed by IEC18 and LT97, whereas peroxidized linoleic acid was most toxic to IEC18 cells. Equimolar concentrations of nonoxidized fatty acids had no significant effects on cell proliferation. Cytotoxic effects of peroxidized fatty acids were accompanied by formation of reactive oxygen species as evidenced by the increased 2,7-dichlorofluorescin fluorescence and protection of cells by radical quenchers such as [alpha]-tocopherol. Thus, according to our data, peroxidized linoleic acid is most toxic to normal intestinal epithelial cells, whereas peroxidized linolenic acid is most toxic to carcinoma cells. These findings may partially explain protection by dietary (n-3) fatty acids against the development of sporadic colon cancer.

Published
2002

53. Studies from S. Tesseraud et al Have Provided New Data on Proinsulin (Modulation of the insulin anabolic signalling cascade in growing chickens by n-3 PUFA)

Subjects
Linolenic acids -- Physiological aspects, Insulin -- Research -- Physiological aspects, Glucose metabolism -- Physiological aspects, Proteins -- Physiological aspects, Health
Abstract

By a News Reporter-Staff News Editor at Health & Medicine Week -- Data detailed on Peptide Proteins have been presented. According to news reporting originating from Paris, France, by NewsRx [...]

Published
2014

55. New Plant Physiology Findings from Hunan Agricultural University Discussed

Subjects
Linolenic acids -- Physiological aspects, Omega-3 fatty acids -- Physiological aspects, Plant physiology -- Physiological aspects, Biological sciences, Health
Abstract

By a News Reporter-Staff News Editor at Life Science Weekly -- Investigators publish new report on Life Science Research. According to news originating from Changsha, People's Republic of China, by [...]

Published
2014

56. Researchers at School of Biochemistry Target Proinsulin

Subjects
Biochemistry -- Physiological aspects, Dextrose -- Physiological aspects, Linolenic acids -- Physiological aspects, Glucose -- Physiological aspects, Glucose metabolism -- Physiological aspects, Proteins -- Physiological aspects, Biological sciences, Health
Abstract

By a News Reporter-Staff News Editor at Life Science Weekly -- Data detailed on Peptide Proteins have been presented. According to news reporting from Santa Fe, Argentina, by NewsRx journalists, [...]

Published
2014

57. Reports from Chinese Academy of Sciences Describe Recent Advances in Plant Physiology

Subjects
Linolenic acids -- Physiological aspects, Omega-3 fatty acids -- Physiological aspects, Plant physiology -- Physiological aspects, Biological sciences, Health, Chinese Academy of Sciences
Abstract

By a News Reporter-Staff News Editor at Life Science Weekly -- Investigators publish new report on Plant Physiology. According to news reporting from Beijing, People's Republic of China, by NewsRx [...]

Published
2013

59. Reports from University of Guelph Provide New Insights into Physiology and Pharmacology

Subjects
Linolenic acids -- Physiological aspects, Omega-3 fatty acids -- Physiological aspects, Pharmaceuticals and cosmetics industries, University of Guelph
Abstract

By a News Reporter-Staff News Editor at Drug Week -- Fresh data on Drugs and Therapies are presented in a new report. According to news reporting originating from Guelph, Canada, [...]

Published
2013

60. New Findings in Physiology and Pharmacology Described by J. Monteiro and Co-Researchers

Subjects
Pharmacology -- Physiological aspects, Linolenic acids -- Physiological aspects, Omega-3 fatty acids -- Physiological aspects, Pharmaceuticals and cosmetics industries
Abstract

By a News Reporter-Staff News Editor at Drug Week -- Researchers detail new data in Physiology and Pharmacology. According to news originating from Winnipeg, Canada, by NewsRx correspondents, research stated, [...]

Published
2013

61. Research from National Institute on Alcohol Abuse Yields New Findings on Metabolism

Subjects
Alcoholism -- Physiological aspects, Monounsaturated fatty acids -- Physiological aspects, Linolenic acids -- Physiological aspects, Omega-3 fatty acids -- Physiological aspects, Health
Abstract

By a News Reporter-Staff News Editor at Pain & Central Nervous System Week -- Current study results on Metabolism have been published. According to news reporting originating from Bethesda, Maryland, [...]

Published
2012

62. Research on Nerve Growth Factor Described by Investigators at Weizmann Institute of Science

Subjects
Nerve growth factor -- Physiological aspects, Unsaturated fatty acids -- Physiological aspects, Linolenic acids -- Physiological aspects, Fatty acids -- Physiological aspects, Omega-3 fatty acids -- Physiological aspects, Health
Abstract

By a News Reporter-Staff News Editor at Health & Medicine Week -- New research on Proteins is the subject of a report. According to news reporting originating from Rehovot, Israel, [...]

Published
2012

63. Data on Central Nervous System Diseases Detailed by Researchers at CHUQ

Subjects
Medical research -- Physiological aspects, Medicine, Experimental -- Physiological aspects, Nervous system diseases -- Physiological aspects, Linolenic acids -- Physiological aspects, Fatty acids -- Physiological aspects, Omega-3 fatty acids -- Physiological aspects, Central nervous system -- Physiological aspects, Health
Abstract

By a News Reporter-Staff News Editor at Pain & Central Nervous System Week -- Investigators publish new report on Central Nervous System Diseases. According to news reporting from Quebec City, [...]

Published
2012

64. Research from Washington State University in the area of metabolism described

Subjects
Linolenic acids -- Reports, Linolenic acids -- Physiological aspects, Universities and colleges -- Reports, Universities and colleges -- Physiological aspects, Triglycerides -- Reports, Triglycerides -- Physiological aspects, Biotechnology industry, Pharmaceuticals and cosmetics industries
Abstract

According to a study from the United States, 'The polyunsaturated fatty acids (PUFAs) linoleic acid (18:2) and alpha-linolenic acid (18:3) in triacylglycerols (TAG) are major factors affecting the quality of [...]

Published
2009

65. Study results from A. Ibrahim and colleagues update understanding of metabolism

Subjects
Linolenic acids -- Research, Linolenic acids -- Physiological aspects, Glucose metabolism -- Research, Glucose metabolism -- Physiological aspects, Dextrose -- Research, Dextrose -- Physiological aspects, Glucose -- Research, Glucose -- Physiological aspects, Omega-3 fatty acids -- Research, Omega-3 fatty acids -- Physiological aspects, Biotechnology industry, Pharmaceuticals and cosmetics industries
Abstract

According to recent research from Hyderabad, India, 'In recent years the intake of n-6 PUFA and trans-fatty acids (TFA) has increased, whereas n-3 PUFA intake has decreased. The present study [...]

Published
2009

66. Researchers from National University provide details of new studies and findings in the area of enzyme research

Subjects
Cyclosporine -- Physiological aspects, Cyclosporine -- Reports, Transplantation of organs, tissues, etc. -- Physiological aspects, Transplantation of organs, tissues, etc. -- Reports, Drugs -- Physiological aspects, Drugs -- Reports, Omega-3 fatty acids -- Physiological aspects, Omega-3 fatty acids -- Reports, Universities and colleges -- Argentina, Universities and colleges -- Physiological aspects, Universities and colleges -- Reports, Linolenic acids -- Physiological aspects, Linolenic acids -- Reports, Enzymes -- Physiological aspects, Enzymes -- Reports, Habitat destruction -- Physiological aspects, Habitat destruction -- Reports
Abstract

According to a study from La Plata, Argentina, "The aim of the present work was to evaluate the influence of cyclosporine (CsA) and sirolimus (SRL) on fatty acid (FA) desaturase [...]

Published
2009

67. New cardiology study results reported from University of Paris

Subjects
Omega-3 fatty acids -- Research, Omega-3 fatty acids -- Physiological aspects, Cardiology -- Research, Cardiology -- Physiological aspects, Universities and colleges -- Research, Universities and colleges -- Physiological aspects, Linolenic acids -- Research, Linolenic acids -- Physiological aspects, Biotechnology industry, Pharmaceuticals and cosmetics industries, University of Paris-Sorbonne
Abstract

According to recent research published in the journal Nutrition & Metabolism, 'Previous work showed that the functional cardiac effect of dietary alpha-linolenic acid (ALA) in rats requires a long feeding [...]

Published
2009

68. Studies from K. Harnack et al have provided new data on enzyme research

Subjects
Hepatoma -- Physiological aspects, Phosphotransferases -- Physiological aspects, Linolenic acids -- Physiological aspects, Enzymes -- Physiological aspects, Omega-3 fatty acids -- Physiological aspects, Biotechnology industry, Pharmaceuticals and cosmetics industries
Abstract

According to recent research published in the journal Nutrition & Metabolism, 'Conversion of linoleic acid ( LA) and alpha-linolenic acid ( ALA) to their higher chain homologues in humans depends [...]

Published
2009

69. Reports from Fukuoka University add new data to research in metabolism

Subjects
Oleic acid -- Physiological aspects, Oleic acid -- Research, Developmental biology -- Physiological aspects, Developmental biology -- Research, Omega-3 fatty acids -- Physiological aspects, Omega-3 fatty acids -- Research, Cell research -- Physiological aspects, Universities and colleges -- Physiological aspects, Universities and colleges -- Research, Linolenic acids -- Physiological aspects, Linolenic acids -- Research, Fatty acids -- Physiological aspects, Fatty acids -- Research, Biotechnology industry, Pharmaceuticals and cosmetics industries
Abstract

According to recent research published in the journal in Vitro Cellular & Developmental Biology - Animal, 'We investigated the effects of stearic acid (saturated), oleic acid (monounsaturated), linoleic acid (n-6 [...]

Published
2009

70. New lipids research from G. Bannenberg et al outlined

Subjects
Linolenic acids -- Physiological aspects, Arabidopsis thaliana -- Physiological aspects
Abstract

"Lipoxygenases (LOX) catalyze the oxygenation of polyunsaturated fatty acids, the first step in the biosynthesis of a large group of biologically active fatty acid metabolites collectively named oxylipins. In the [...]

Published
2009

71. Scientists at Pennsylvania State University publish new data on science

Subjects
Linolenic acids -- Physiological aspects, Cell research -- Physiological aspects, Glutamine -- Physiological aspects, Universities and colleges -- Physiological aspects, Scientists -- Physiological aspects, Drugs -- Physiological aspects, Health, Science and technology, National Academy of Sciences, The Pennsylvania State University
Abstract

According to recent research published in the journal Proceedings of the National Academy of Sciences of the United States of America, 'Since the first fatty acid amino acid conjugate (FAC) [...]

Published
2009

72. Scientists at National Institute on Alcohol Abuse and Alcoholism report research in life sciences

Subjects
Alcoholism -- Reports, Alcoholism -- Physiological aspects, Trade and professional associations -- Reports, Trade and professional associations -- Physiological aspects, Omega-3 fatty acids -- Reports, Omega-3 fatty acids -- Physiological aspects, Scientists -- Reports, Scientists -- Physiological aspects, Linolenic acids -- Reports, Linolenic acids -- Physiological aspects, Biotechnology industry, Pharmaceuticals and cosmetics industries
Abstract

Scientists discuss in 'Effect of dietary docosahexaenoic acid on biosynthesis of docosahexaenoic acid from alpha-linolenic acid in young rats' new findings in life sciences. 'Docosahexaenoic acid (DHA), a crucial nervous [...]

Published
2008

73. Data from University of British Columbia provide new insights into physiology

Subjects
Linolenic acids -- Reports, Linolenic acids -- Physiological aspects, Universities and colleges -- Reports, Universities and colleges -- Physiological aspects, Omega-3 fatty acids -- Reports, Omega-3 fatty acids -- Physiological aspects
Abstract

"Cardiac proinflammatory pathways are altered with different dietary n-6 linoleic to n-3 alpha-linolenic acid ratios in normal, fat-fed pigs (see also Physiology). Am J Physiol Heart Circ Physiol 293: H2919-H2927, [...]

Published
2008

74. New physiology study findings have been reported from A. Ayalew-Pervanchon et al

Subjects
Linolenic acids -- Reports, Linolenic acids -- Physiological aspects, Linolenic acids -- Analysis, Omega-3 fatty acids -- Reports, Omega-3 fatty acids -- Physiological aspects, Omega-3 fatty acids -- Analysis
Abstract

Research findings, 'Long-term effect of dietary {alpha}-linolenic acid or decosahexaenoic acid on incorporation of decosahexaenoic acid in membranes and its influence on rat heart in vivo,' are discussed in a [...]

Published
2007

75. Reports summarize metabolism study results from Colorado State University

Subjects
Colorado State University -- Reports, Peptide hormones -- Reports, Peptide hormones -- Physiological aspects, Peptide hormones -- Research, Omega-3 fatty acids -- Reports, Omega-3 fatty acids -- Physiological aspects, Omega-3 fatty acids -- Research, Universities and colleges -- Reports, Universities and colleges -- Physiological aspects, Universities and colleges -- Research, Linolenic acids -- Reports, Linolenic acids -- Physiological aspects, Linolenic acids -- Research
Abstract

Fresh data on metabolism are presented in the report 'Adiponectin levels are reduced, independent of polymorphisms in the adiponectin gene, after supplementation with alpha-linolenic acid among healthy adults.' "Our first [...]

Published
2007

76. Investigators at Flinders University target lipid research

Subjects
Blood lipids -- Physiological aspects, Plant lipids -- Physiological aspects, Omega-3 fatty acids -- Physiological aspects, Universities and colleges -- Physiological aspects, Linolenic acids -- Physiological aspects
Abstract

Data detailed in "Competition between 24:5n-3 and ALA for Delta 6 desaturase may limit the accumulation of DHA in HepG2 cell membranes" have been presented. "The use of Delta 6 [...]

Published
2007

77. Data from George Washington University advance knowledge in metabolism

Subjects
George Washington University, Linolenic acids -- Physiological aspects, Universities and colleges -- Physiological aspects, Lipids -- Physiological aspects
Abstract

New investigation results, "Reverse cholesterol transport is regulated by varying fatty acyl chain saturation and sphingomyelin content in reconstituted high-density lipoproteins," are detailed in a study published in Metabolism. "Because [...]

Published
2007

78. New research on biochemistry from Ochanomizu University summarized

Subjects
Universities and colleges -- Japan, Universities and colleges -- Reports, Universities and colleges -- Physiological aspects, Universities and colleges -- Research, Linolenic acids -- Reports, Linolenic acids -- Physiological aspects, Linolenic acids -- Research, Biochemistry -- Reports, Biochemistry -- Physiological aspects, Biochemistry -- Research
Abstract

Research findings, "Distribution and metabolism of dihomo-gamma-linolenic acid (DGLA, 20:3n-6) by oral supplementation in rats," are discussed in a new report. According to a study from Tokyo, Japan, "We compared [...]

Published
2007

79. Reports from France, Germany and Argentina advance knowledge in diet & nutrition research

Subjects
Saturated fatty acids -- Physiological aspects, Diabetes -- Physiological aspects, Linolenic acids -- Physiological aspects, Omega-3 fatty acids -- Physiological aspects, Diet -- Physiological aspects, Health, Science and technology, Physiological aspects
Abstract

Reports from France, Germany and Argentina highlight recent research in diet & nutrition. Study 1: Gender-related differences were found in the response of lipid metabolism to dietary fatty acids in [...]

Published
2006

80. Reports from France, Germany and Argentina advance knowledge in diet & nutrition research

Subjects
Saturated fatty acids -- Physiological aspects, Diabetes -- Physiological aspects, Linolenic acids -- Physiological aspects, Omega-3 fatty acids -- Physiological aspects, Diet -- Physiological aspects, Health, Physiological aspects
Abstract

Reports from France, Germany and Argentina highlight recent research in diet & nutrition. Study 1: Gender-related differences were found in the response of lipid metabolism to dietary fatty acids in [...]

Published
2006

81. Reports from France, Germany and Argentina advance knowledge in diet & nutrition research

Subjects
Diabetes -- Physiological aspects, Diet -- Physiological aspects, Medical research -- Physiological aspects, Medicine, Experimental -- Physiological aspects, Omega-3 fatty acids -- Physiological aspects, Linolenic acids -- Physiological aspects, Fatty acids -- Physiological aspects
Abstract

Reports from France, Germany and Argentina highlight recent research in diet & nutrition. Study 1: Gender-related differences were found in the response of lipid metabolism to dietary fatty acids in [...]

Published
2006

82. Gender-related differences found in lipid metabolism response to dietary fatty acids

Subjects
Saturated fatty acids -- Physiological aspects, Linolenic acids -- Physiological aspects, Triglycerides -- Physiological aspects, Omega-3 fatty acids -- Physiological aspects, Health, Science and technology, Physiological aspects
Abstract

Gender-related differences were found in the response of lipid metabolism to dietary fatty acids in a hamster model. According to recent research from France, "Gender and dietary fatty acids are [...]

Published
2006

83. Gender-related differences found in lipid metabolism response to dietary fatty acids

Subjects
Triglycerides -- Physiological aspects, Linolenic acids -- Physiological aspects, Omega-3 fatty acids -- Physiological aspects, Fatty acids -- Physiological aspects
Abstract

Gender-related differences were found in the response of lipid metabolism to dietary fatty acids in a hamster model. According to recent research from France, "Gender and dietary fatty acids are [...]

Published
2006

84. Gender-related differences found in lipid metabolism response to dietary fatty acids

Subjects
Saturated fatty acids -- Physiological aspects, Linolenic acids -- Physiological aspects, Triglycerides -- Physiological aspects, Omega-3 fatty acids -- Physiological aspects, Health, Physiological aspects
Abstract

Gender-related differences were found in the response of lipid metabolism to dietary fatty acids in a hamster model. According to recent research from France, "Gender and dietary fatty acids are [...]

Published
2006

86. Fatty acids in Japanese herbal medicine promote stem cell proliferation

Author

Clark, Cathy

Subjects
Cell proliferation -- Causes of -- Physiological aspects, Linolenic acids -- Physiological aspects, Medicine, Botanic -- Physiological aspects, Hematopoietic stem cells -- Physiological aspects, Medicine, Herbal -- Physiological aspects, Oleic acid -- Physiological aspects, Health, Physiological aspects, Causes of
Abstract

Stromal cells may be involved with the stimulation of hematopoietic stem cell (HSC) proliferation. Hiroko Hisha, Kansai Medical University, Moriguchi City, Osaka, Japan, and colleagues said that their data might [...]

Published
1997

87. Effect of different levels of w-3 polyunsaturated fatty acid (PUFA) alpha-linolenic acid in a medium-fat diet on colon carcinogenesis in F344 rats

Author

Narisawa, T., Fukaura, Y., Yazawa, K., Ishikawa, C., Isoda, Y., and Nishizawa, Y.

Subjects
Unsaturated fatty acids -- Physiological aspects, Linolenic acids -- Physiological aspects, Colorectal cancer -- Health aspects, Business, Health care industry
Abstract

AUTHORS: T. Narisawa, Y. Fukaura, K. Yazawa, C. Ishikawa, Y. Isoda and Y. Nishizawa. Akita University College of Allied Medical Science, Sagami Chemical Research Center, Kanagawa, Japan, and Nippon Oil [...]

Published
1994

88. Effect of temperature and oxygen tension on gamma-linolenate toxicity towards human breast cancer cells

Author

Ells, G.W., Cantrill, R.C., Chisholm, K.A., Hughes, B.J., and Horrobin, D.F.

Subjects
Linolenic acids -- Physiological aspects, Antineoplastic agents -- Research, Business, Health care industry
Abstract

AUTHORS: G.W. Ells, R.C. Cantrill, K.A. Chisholm, B.J. Hughes and D.F. Horrobin. Efamol Research Institute, Kentville, N.S., Canada. According to an abstract presented during an extended session of the Eighty-Fourth [...]

Published
1993

Catalog

Books, media, physical & digital resources
See catalog results