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Surveying data for wind lodging disaster happening in Nanyang of Henan Province in August 1, 2013, were used to analyze the effects of strong wind lodging at pre- and post-tasseling stages on growth and yield of summer maize, and to determine the differences in lodging resistance among varieties and the suitable sowing time for summer maize. The survey included two varieties of summer maize, Xundan 20 and Zhengdan 958, with five and three sowing dates, respectively. The lodging was divided into four types, i.e., root slope (RS), root lodging (RL), stem bending (SB) and stem broken (SBK). The results showed that wind lodging occurring at pre- and post-tasseling stages resulted in high lodging percentages for both varieties and all sowing dates. The lodging percentage of Xundan 20 variety ranged between 86.0% and 98.5% for five sowing dates. For Zhengdan 958 variety, it ranged between 60.0% and 76.4% for three sowing dates. After tasseling, the earlier the sowing date, the lower the lodging rate occurred. The main lodging types happening around the tasseling stage were RL with the lodging rate of 53.0%–84.3% for sowing dates II-V of Xundan 20. The main lodging type for sowing date I was SB with the lodging rate of 37.5%. Lodging reduced the aboveground dry matter with the greatest reduction rate occurring in SB, followed by RS and RL. Lodging increased the allocation of dry matter to leaves and stems, but decreased the allocation to spikes. RL and SB shortened the length and diameter of spike, and reduced the grain number per spike. The lodging occurring after the tasseling stage also reduced 100-grain mass. RS had no significant effects on spike characters and yield components. The lodging had serious effects on the yield of summer maize. The yield loss was highest for SB with the reduction percentages of 74.2% and 68.7% for Xundan 20 and Zhengdan 958, respectively. SB occurring before the tasseling stage would lead to a complete crop failure. RL decreased the average yield by 46.3% and 46.5% for Xundan 20 and Zhengdan 958, respectively. RS decreased the averaged yield by 8.4% and 13.2% for Xundan 20 and Zhengdan 958, respectively. The mean yields of Xundan 20 and Zhengdan 958 were 4959.9 and 6026.1 kg·hm-2 after the wind lodging, respectively. The later the sowing date, the higher the yield loss rate was observed for Xundan 20, however, there were no significant difference in yield loss among different sowing dates of Zhengdan 958. In general, Zhengdan 958 had stronger lodging resistance than Xundan 20. [ABSTRACT FROM AUTHOR]

In the present study, the molecular mechanisms underlying kainate-induced neurotoxicity were characterized in cultured rat hippocampal neurons. Long-term exposure to kainate caused typically apoptotic cell death, which was accompanied by the accumulation of calcium, marked down-regulation of GluR2 subunit, and the activation of calpain and caspase-3. All these alterations were prevented by alpha-amino-3-hydroxy-5-methylisoxazole-4-proprionic acid (AMPA) receptor antagonist CNQX, but not by NMDA receptor antagonist MK801 and membrane L-type calcium channel antagonist nifedipine. In the presence of cyclothiazide, kainate-induced neurotoxicity was significantly enhanced. Inhibition of either caspases by zVAD-fmk or calpains by calpeptin protected neurons from neurotoxicity. These results suggest that long-term exposure of hippocampal neurons to kainate causes apoptosis, whose mechanisms involve multiple Ca2+-dependent cascades, in which AMPA receptor subunits may be targets for Ca2+-activated protease-mediated degradation during kainate-induced neuron apoptosis. [Copyright &y& Elsevier]

The title compound, C18H7BrCl3F3N4, is an imine relevant to insecticides. The dihedral angles between the central pyrazole ring and the benzene ring planes are 84.3 (2) and 68.5 (2)°. [ABSTRACT FROM AUTHOR]

The title compound, C16H6BrCl2F3N4O, is an imine with an overall Y-shape. The dihedral angles between the pyrazole ring and the benzene and furan ring planes are 88.6 (2) and 65.5 (2)°, respectively. [ABSTRACT FROM AUTHOR]

Objective: The objective of this study was to evaluate the effects of comfort care on perioperative outcomes and postoperative recovery of breast cancer patients. Evaluating comfort care is important in the context of breast cancer surgery because it can potentially alleviate pain, improve patient comfort, enhance postoperative recovery, and reduce complications, ultimately leading to better patient outcomes., Methods: Between March 2020 and December 2021, 78 patients undergoing breast cancer surgery at our hospital were randomly assigned to receive either routine nursing (routine group) or comfort care (experimental group). The comfort care intervention included various components such as health education, preoperative care, intraoperative care, postoperative care, pain care, and psychological care. The routine group received standard nursing care following medical advice., Results: The patient characteristics between the two groups were comparable. Comfort care resulted in significantly higher visual analog scale (VAS) scores, indicating reduced pain, and better improvement in functional recovery of the upper limb compared to routine nursing. Comfort care was also associated with better postoperative recovery, as evidenced by lower self-rating depression scale (SDS) and self-rating anxiety scale (SAS) scores. The experimental group had a significantly lower incidence of complications compared to the routine group. Additionally, the experimental group reported better 24-hour comfort and higher nursing satisfaction., Conclusion: In conclusion, comfort care effectively reduces postoperative pain, promotes postoperative recovery, improves patient emotions, lowers the incidence of complications, and enhances comfort and care satisfaction in breast cancer patients undergoing radical surgery. These findings highlight the importance of incorporating comfort care interventions in the perioperative management of breast cancer patients. Further research and implementation of comfort care strategies may have implications for improving clinical practice and patient outcomes in the future.

The main wheat production area in Henan Province was classified into five regions based on observed wheat production data, historical meteorological data and soil data from thirty sites du-ring 1981 to 2014. The changes in the risk of yield loss of winter wheat under water stress condition in each region were calculated with WOFOST model. From 1981 to 2014, the yield reduction rate of winter wheat showed an increasing trend at all the sites with the increase rate of 2.8%-5.0% per 10 years. The yield reduction rate decreased from north to south in Henan Province. The event of yield reduction rate over 20% occurred about once every 10 years in southern Henan Province, and once every 2 years at Xinxiang, Fengqiu and Puyang in northern Henan Province. The event of yield reduction rate over 50% occurred about once every 3 years at Xinxiang and Zhengzhou but was rare in southern Henan Province. The highest hazard areas were mainly distributed in north and middle parts of Henan Province, the lowest hazard areas were distributed at Lushi in western Henan Pro-vince, Nanyang in southwestern Henan Province, Xinyang in southern Henan Province and south part of Zhumadian, the medium hazard areas were distributed in the other regions of Henan Province.

Objective: To investigate whether right ventricular hypertrophy in hypoxic pulmonary hypertension (HPH) rats could be prevented by treatment with Rho kinase inhibitor fasudil., Methods: The rat model of pulmonary hypertension was established by exposing rats to normobaric intermitent hypoxia [(10 ± 0.5)% O2]. Twenty-four Spraque-Dawley male rats were randomly divided into control group, hypoxic model group and hypoxia with fasudil groups (n=8 each). The mean pulmonary arterial pressure (mPAP), and right ventricle hypertrophy index (RVHI) were measured. Ultrastructure of the right ventricular myocardial cells was observed under transmission electron microscope (TEM). -, Results: The level of mPAP (31.38 ± 1.98) mmHg and RVHI (0.47 ± 0.03) were significantly higher in the hypoxic model group than (15.25 ± 0.91) mmHg and (0.25 ± 0.02) in control group respectively (P<0.01). Transmission electron microscope (TEM) revealed the model group right ventricular mitochondria increased significantly, swelling, cristae blurred, lost, heart muscle Siming dark band was not clear. The level of mPAP (16.63 ± 1.53) mmHg and RVHI (0.27 ± 0.02) were significantly lower in fasudil treatment group than in model group respectively (P<0.01). After the intervention of fasudil right ventricular myocardial injury was significantly reduced., Conclusions: Fasudil may partly prevent and reverse the development of pulmonary hypertension and right ventricular hypertrophy and myocardial cell injury.

Surveying data for wind lodging disaster happening in Nanyang of Henan Province in August 1, 2013, were used to analyze the effects of strong wind lodging at pre- and post-tasseling stages on growth and yield of summer maize, and to determine the differences in lodging resistance among varieties and the suitable sowing time for summer maize. The survey included two varieties of summer maize, Xundan 20 and Zhengdan 958, with five and three sowing dates, respectively. The lodging was divided into four types, i.e., root slope ( RS) , root lodging ( RL) , stem bending (SB) and stem broken (SBK). The results showed that wind lodging occurring at pre- and post-tasseling stages resulted in high lodging percentages for both varieties and all sowing dates. The lodging percentage of Xundan 20 variety ranged between 86.0% and 98.5% for five sowing dates. For Zhengdan 958 variety, it ranged between 60.0% and 76.4% for three sowing dates. After tasseling, the earlier the sowing date, the lower the lodging rate occurred. The main lodging types happening around the tasseling stage were RL with the lodging rate of 53.0%-84.3% for sowing dates II-V of Xundan 20. The main lodging type for sowing date I was SB with the lodging rate of 37.5%. Lodging reduced the aboveground dry matter with the greatest reduction rate occurring in SB, followed by RS and RL. Lodging increased the allocation of dry matter to leaves and stems, but decreased the allocation to spikes. RL and SB shortened the length and diameter of spike, and reduced the grain number per spike. The lodging occurring after the tasseling stage also reduced 100-grain mass. RS had no significant effects on spike characters and yield components. The lodging had serious effects on the yield of summer maize. The yield loss was highest for SB with the reduction percentages of 74.2% and 68.7% for Xundan 20 and Zhengdan 958, respectively. SB occurring before the tasseling stage would lead to a complete crop failure. RL decreased the average yield by 46.3% and 46.5% for Xundan 20 and Zhengdan 958, respectively. RS decreased the averaged yield by 8.4% and 13.2% for Xundan 20 and Zhengdan 958, respectively. The mean yields of Xundan 20 and Zhengdan 958 were 4959.9 and 6026.1 kg · hm(-2) after the wind lodging, respectively. The later the sowing date, the higher the yield loss rate was observed for Xundan 20, however, there were no significant difference in yield loss among different sowing dates of Zhengdan 958. In general, Zhengdan 958 had stronger lodging resistance than Xundan 20.

Objective: To obtain the prevalence of allergic rhinitis (AR) in different regions of northern China, to analyze the correlation and interaction between AR and bronchial asthma (BA) or atopic dermatitis (AD), and to provide reference for the prevention and treatment of allergic diseases such as AR., Methods: To obtain the indexes including age, occupation, atopic physical fitness, smoking, alcohol, lifestyle and so on. To explore the correlation between AR and BA or AD. From April 2007 to May 2010, the serum specific IgE (sIgE) was investigated in different regions (rural areas of Qingxian, Hebei; coastal fishing village of Bohai Bay, Huanghua; area of Wuling Mountain, Chengde; urban areas of Tianjin) by randomly multi-stage and cluster sampling, with total population of 1524., Results: The prevalence of AR, BA and AD were 9.1%, 5.4% and 6.0%. The prevalence of BA and AD were 30.9% and 29.5% in AR patients, but were 2.9% and 3.7% in non-AR, and the differences were of statistical significance (χ(2) values were 192.97 and 148.40, respectively, all P < 0.01). The risk of people with BA suffering from AR was as 8.619 times as those free from BA, the risk of people with AD suffering from AR was as 1.817 times as those free from AD and, the risk of workers suffering from AR was as 2.320 times as farmers in terms of working factor by analysis of Logistic regression for AR and BA, AD, age, occupation, atopic physical fitness and other factors., Conclusions: The prevalence of AR are correlated with BA and AD. It is greater between BA and AR than AD and AR in the strength of correlation.

Objective: To obtain the prevalence and related factors in allergic rhinitis (AR) and other allergic diseases in rural area in China through epidemiological investigation with large sample and multi-faceted survey data., Methods: Face to face survey was conducted in different regions (rural areas of Cangzhou, Hebei, coastal fishing village of Bohai Bay, area of Wuling Mountain, Chengde, urban areas of Tianjin) from April 2007 to May 2009. In the same time, serum specific IgE (sIgE) was detected in the digits of every 0, 1or 5 in them. SPSS 13.0 software was used to analyze the data., Results: Five thousand and ten cases were investigated. There were 823 cases with the symptoms or signs of AR (16.4%). Four hundred and two cases were found to have positive serum sIgE antibody in 1576 detected cases (25.5%). One hundred and fourty-six cases with nasal allergic symptoms or signs were diagnosed as AR. The incidence of AR was 9.3% (146/1576). The occurrence of allergic symptoms or signs had a significant statistical difference with factors such as age, occupation, atopic constitution (χ(2) value were 7.96, 9.73, 16.53, 8.95 respectively, all P < 0.05), and it was closely related to lower respiratory tract allergies (β = 2.544, P < 0.01). The most common allergens were dog and cat epithelium in rural areas and dust mites in city., Conclusions: The incidence of AR is higher whether in urban or rural areas, it should be taken seriously as the impact on human health. The occurrence is closely related to physical characteristics and environmental factors.