Search

Your search keyword '"Li, Qiuyun"' showing total 307 results
Start Over Author "Li, Qiuyun"
307 results on '"Li, Qiuyun"'

53. STIM1-regulated exosomal EBV-LMP1 empowers endothelial cells with aggressive phenotype by activating the Akt/ERK pathway in nasopharyngeal carcinoma

Author

Deng, Yayan, primary, Liu, Xue, additional, Huang, Yujuan, additional, Ye, Jiaxiang, additional, He, Qian, additional, Luo, Yue, additional, Chen, Yong, additional, Li, Qiuyun, additional, Lin, Yan, additional, Liang, Rong, additional, Li, Yongqiang, additional, Wei, Jiazhang, additional, and Zhang, Jinyan, additional

Published
2023
Full Text
View/download PDF

54. Abstract OT2-22-01: Epirubicin, cyclophosphamide and pyrotinib followed by docetaxel, trastuzumab and pyrotinib as neoadjuvant therapy for stage II-III HER2-positive breast cancer: a single-arm, multicenter phase 2 trial

Author

Shi, Qiyun, primary, Qi, Xiaowei, additional, Tang, Peng, additional, Fan, Linjun, additional, Chen, Li, additional, Wang, Shushu, additional, Zhang, Guozhi, additional, Wang, Mengyuan, additional, Che, Hongying, additional, Lv, Pengwei, additional, Chen, Dejie, additional, Hu, Jinhui, additional, Li, Qiuyun, additional, Zhang, Yanwu, additional, Yu, Qiao, additional, Yang, Kunxian, additional, Zhong, Yuan, additional, Chen, Chuang, additional, Zhou, Zemin, additional, Qian, Liyuan, additional, Zhang, Jingwei, additional, Ma, Mingde, additional, Sun, Yi, additional, Liu, Jiangbo, additional, Zhang, Yi, additional, and Jiang, Jun, additional

Published
2023
Full Text
View/download PDF

56. The miRNA-185-5p/STIM1 Axis Regulates the Invasiveness of Nasopharyngeal Carcinoma Cell Lines by Modulating EGFR Activation-Stimulated Switch from E- to N-Cadherin

Author

Luo, Yue, primary, Ye, Jiaxiang, additional, Deng, Yayan, additional, Huang, Yujuan, additional, Liu, Xue, additional, He, Qian, additional, Chen, Yong, additional, Li, Qiuyun, additional, Lin, Yan, additional, Liang, Rong, additional, Li, Yongqiang, additional, Wei, Jiazhang, additional, and Zhang, Jinyan, additional

Published
2023
Full Text
View/download PDF

57. Neoadjuvant Pyrotinib and Trastuzumab Plus Chemotherapy in the Treatment of HER2-Positive Breast Cancer: A Multicenter, Single-Arm, Phase II Trial

Author

Shi, Qiyun, primary, Qi, Xiaowei, additional, Tang, Peng, additional, Fan, Linjun, additional, Chen, Li, additional, Wang, Shushu, additional, Liang, Yan, additional, Hu, Ying, additional, Wang, Minghao, additional, Ren, Lin, additional, Zhang, Guozhi, additional, Tan, Xuanni, additional, Wang, Mengyuan, additional, Che, Hongying, additional, Lv, Pengwei, additional, Chen, Dejie, additional, Hu, Jinhui, additional, Li, Qiuyun, additional, Zhang, Yanwu, additional, Yang, Kunxian, additional, Zhong, Yuan, additional, Chen, Chuang, additional, Zhou, Zemin, additional, Qian, Liyuan, additional, Zhang, Jingwei, additional, Ma, Mingde, additional, Shun, Yi, additional, Zhang, Yi, additional, and Jiang, Jun, additional

Published
2023
Full Text
View/download PDF

71. Synthesis of 2‐Pyrones by Base‐Induced [3+3] Annulation Reaction of Phenacyl Phosphonium Ylides with Cyclopropenones

Author

Zhang, Yuanyuan, Wang, Xiaoyu, Wen, Jiangwei, Li, Qiuyun, Xue, Wenyue, Liu, Hancong, and Yan, Kelu

Abstract

The base‐induced [3+3] annulation reaction of phenacyl phosphonium ylides with cyclopropenones has been proposed. Various polysubstituted 2‐pyrones are achieved in moderate to good yields through C−P bond cleavage and C−O/C−C coupling under simple and easy‐to‐operate conditions. The synthetic application and reaction mechanism have also been preliminarily explored to gain a deeper understanding of this strategy in practicality and reaction details. This protocol offers an alternative approach for the synthesis of useful 2‐pyrone derivatives. The base‐induced [3+3] annulation reaction of phenacyl phosphonium ylides with cyclopropenones is proposed for the preparation of 2‐pyrones through C−P bond cleavage and further C−O/C−C coupling. This transformation exhibits good functional group tolerance. The synthetic application and reaction mechanism have also been preliminarily explored to gain a deeper understanding of this strategy in practicality and reaction details.

Published
2025
Full Text
View/download PDF

72. Inverse correlation of miR-27a-3p and CDH5 expression serves as a diagnostic biomarker of proliferation and metastasis of clear cell renal carcinoma

Author

Wang, Yifang, primary, Zhou, Xiaohui, additional, Han, Peipei, additional, Lu, Yunliang, additional, Zhong, Xuemin, additional, Yang, Yanping, additional, Li, Danping, additional, Liu, Deling, additional, Li, Qiuyun, additional, Pan, Nenghui, additional, Mo, Yingxi, additional, Luo, Wenqi, additional, Li, Ping, additional, Zhou, Xiaoying, additional, and Liudmila, Matskova, additional

Published
2021
Full Text
View/download PDF

79. Inverse Correlation of miR-27a-3p and CDH5 Expression Serves as a Diagnostic Biomarker of Proliferation and Metastasis of Clear Cell Renal Carcinoma

Author

Wang, Yifang, primary, Zhou, Xiaohui, additional, Han, Peipei, additional, Lu, Yunliang, additional, Zhong, Xuemin, additional, Yang, Yanping, additional, Li, Danping, additional, Liu, Deling, additional, Li, Qiuyun, additional, Pan, Nenghui, additional, Mo, Yingxi, additional, Luo, Wenqi, additional, Li, Ping, additional, Zhou, Xiaoying, additional, and Matskova, Liudmila, additional

Published
2020
Full Text
View/download PDF

80. Clinical significance of single and persistent elevation of serum high-sensitivity C-reactive protein levels for prediction of kidney outcomes in patients with impaired fasting glucose or diabetes mellitus

Author

Liu, Lili, primary, Gao, Bixia, additional, Wang, Jinwei, additional, Yang, Chao, additional, Wu, Shouling, additional, Wu, Yuntao, additional, Chen, Shuohua, additional, Li, Qiuyun, additional, Zhang, Huifen, additional, Wang, Guodong, additional, Chen, Min, additional, Zhao, Ming-hui, additional, and Zhang, Luxia, additional

Published
2020
Full Text
View/download PDF

81. Reduction in Serum High-Sensitivity C-Reactive Protein Favors Kidney Outcomes in Patients with Impaired Fasting Glucose or Diabetes

Author

Liu, Lili, primary, Gao, Bixia, additional, Wang, Jinwei, additional, Yang, Chao, additional, Wu, Shouling, additional, Wu, Yuntao, additional, Chen, Shuohua, additional, Li, Qiuyun, additional, Zhang, Huifen, additional, Wang, Guodong, additional, Chen, Min, additional, Zhao, Ming-hui, additional, and Zhang, Luxia, additional

Published
2020
Full Text
View/download PDF

82. Estradiol promotes the progression of ER+ breast cancer through methylation-mediated RSK4 inactivation

Author

Li,Qiuyun, Gao,Hui, Yang,Huawei, Wei,Wei, and Jiang,Yi

Subjects
OncoTargets and Therapy
Abstract

Qiuyun Li,1,* Hui Gao,2,* Huawei Yang,1 Wei Wei,1 Yi Jiang11Department of Breast Surgery, The Affiliated Tumor Hospital of Guangxi Medical University, Nanning, Guangxi 530021, People’s Republic of China; 2Department of Breast Surgery, Ruikang Hospital Affiliated to Guangxi University of Chinese Medicine, Nanning, Guangxi 530001, People’s Republic of China*These authors contributed equally to this workBackground: It’s well documented that estrogen plays a vital role in breast cancer progression, but the molecular mechanisms underlying it still remains incompletely clear. This study aimed to explore whether ribosomal protein S6 kinase 4 (RSK4) was involved in estrogen-induced breast cancer development and its underlying mechanism.Methods: The expressions of estrogen receptor (ER) and RSK4 were assessed by immunohistochemistry, RT-PCR and Western blotting. The methylation of RSK4 promoter was evaluated by bisulfite genomic sequencing. MTT, clone formation, flow cytometry and Transwell chamber assays were performed to detect cell proliferation, clone formation, apoptosis and invasion abilities. Luciferase gene reporter assay was used to detect the transcriptional activity of RSK4. The expressions of methyltransferases, such as DNMT1, DNMT3A and DNMT3B were tested by Western blotting.Results: ER expression and RSK4 methylation were significantly elevated in ER positive (ER+) breast cancer tissues and MCF-7 cells, whereas RSK4 expression was reduced. 17β-estradiol (E2) treatment obviously decreased RSK4 expression and transcriptional activity, as well as promoted cell proliferation, clone formation and invasion and reduced cell apoptosis in ER+ MCF-7 cells. Furthermore, E2 reduced RSK4 expression through promoting DNMT3B-induced RSK4 methylation.Conclusion: In summary, the present study reveals that estrogen promotes the progression of breast cancer through methylation-mediated RSK4 inactivation in ER+ breast cancer. Our study might provide a novel target for the treatment of ER+ breast cancer.Keywords: estrogen, RSK4, DNMT3B, ER positive, methylation

Published
2019

85. Efficacy of metformin in preventing progression to diabetes in a Chinese population with impaired glucose regulation: Protocol for a multicentre, open‐label, randomized controlled clinical study

Author

Ji, Linong, primary, Sun, Ningling, additional, Zhang, Yunliang, additional, Zhang, Lihui, additional, Shen, Sheng'ai, additional, Wang, Xueying, additional, Li, Qiuyun, additional, Dong, Luling, additional, Ren, Weidong, additional, Qi, Lin, additional, Li, Yufeng, additional, Yan, Shuang, additional, Cheng, Wenli, additional, Kuang, Hongyu, additional, and Li, Guangwei, additional

Published
2019
Full Text
View/download PDF

90. Light‐Driven Syngas Production over Defective ZnIn2S4 Nanosheets.

Author

Wang, Xuanwei, Chen, Jianfeng, Li, Qiuyun, Li, Lingyun, Zhuang, Zanyong, Chen, Fei‐Fei, and Yu, Yan

Subjects
SYNTHESIS gas, NANOSTRUCTURED materials, CARBON dioxide adsorption, PHOTOCATALYSIS, HYDROGEN evolution reactions, PRECIOUS metals, CHEMICAL-looping combustion, GREENHOUSE effect
Abstract

Photocatalytic syngas (CO and H2) production with CO2 as gas source not only ameliorates greenhouse effect, but also produces valuable chemical feedstocks. However, traditional photocatalytic systems require noble metal or suffers from low yield. Here, we demonstrate that S vacancies ZnIn2S4 (VS‐ZnIn2S4) nanosheets are an ideal photocatalyst to drive CO2 reduction into syngas. It is found that building S vacancies can endow ZnIn2S4 with stronger photoabsorption, efficient electron–hole separation, and larger CO2 adsorption, finally promoting both hydrogen evolution reaction (HER) and CO2 reduction reaction (CO2RR). The syngas yield of CO and H2 is therefore significantly increased. In contrast to pristine ZnIn2S4, the syngas yield over VS‐ZnIn2S4 can be improved by roughly ≈4.73 times and the CO/H2 ratio is modified from 1:4.18 to 1:1. Total amount of syngas after 12 h photocatalysis is as high as 63.20 mmol g−1 without use of any noble metals, which is even higher than those of traditional noble metal‐based catalysts in the reported literatures. This work demonstrates the critical role of S vacancies in mediating catalytic activity and selectivity, and highlights the attractive ability of defective ZnIn2S4 for light‐driven syngas production. [ABSTRACT FROM AUTHOR]

Published
2021
Full Text
View/download PDF

95. Comparison of the efficacy and survival analysis of neoadjuvant chemotherapy for Her-2-positive breast cancer

Author

Li,Si, Wei,Wei, Jiang,Yi, Li,Qiuyun, Huang,Qinghua, Yang,Huawei, Liu,Jianlun, Li,Si, Wei,Wei, Jiang,Yi, Li,Qiuyun, Huang,Qinghua, Yang,Huawei, and Liu,Jianlun

Abstract

Si Li,1,* Wei Wei,1,* Yi Jiang,1 Qiuyun Li,1 Qinghua Huang,1 Huawei Yang,1 Jianlun Liu1,2 1Department of Breast Surgery, The Affiliated Tumor Hospital of Guangxi Medical University, Nanning, Guangxi, China; 2Department of General Surgery, Longdong Hospital of Guangxi Medical University, Nanning, Guangxi, China *These authors contributed equally to this work Purpose: The objective of this research was to compare the short- and long-term efficacy of the following four neoadjuvant chemotherapy (NAC) regimens: docetaxel/carboplatin/trastuzumab (TCH), docetaxel/epirubicin/cyclophosphamide (TEC), Xeloda/epirubicin/cyclophosphamide followed by Xeloda/docetaxel (XEC-XT), and 5-fluorouracil/epirubicin/cyclophosphamide followed by docetaxel (FEC-T) in human epidermal growth factor receptor-2-positive (Her-2-positive) breast cancer. Patients and methods: According to treatment preferences, 139 patients with Her-2-positive breast cancer were divided into the following four groups: 39 patients in the TCH group, 35 patients in the TEC group, 33 patients in the XEC-XT group, and 32 patients in the FEC-T group. The primary end points were disease-free survival (DFS) and 5-year overall survival (5-year OS). The secondary end points were the efficacy and toxicity of NAC. Results: The TCH, TEC, XEC-XT, and FEC-T groups demonstrated overall response rates of 87.1%, 74.3%, 75.8%, and 62.5% (P=0.031), respectively, and pathological complete response rates of 25.6%, 18.2%, 20.0%, and 18.2% (P=0.041), respectively. The DFS rates for the TCH, TEC, XEC-XT, and FEC-T groups were 84.6%, 62.9%, 65.7%, and 46.9% (P=0.01), respectively. The 5-year OS rates for the TCH, TEC, XEC-XT, and FEC-T groups were 87.2%, 69.7%, 71.4%, and 59.4% (P=0.069), respectively. The mean survival time was 59.3 months (TCH group), 53.5 months (TEC group), 55.3 months (XEC-XT group), and 52.4 months (FEC-T group). The difference in survival among the four groups was statistically significant (P=0.04). Conclusi

Published
2018

96. Does electronic customer relationship management affect customer satisfaction and trust?

Author

Lam, Hoang Chau and Li, Qiuyun

Subjects
E-CRM, customer satisfaction, trust, live chat system, e-service quality, Business Administration, Företagsekonomi
Abstract

Aim: This paper aims to explore and to understand how the E-CRM affects customer satisfaction and trust from customer perspectives in electronic commerce. Method: The research is an exploratory and qualitative study. A multiple case study involving 3 Swedish companies with 12 face-to-face interviews in Gävle, Sweden, was chosen to collect the empirical data for this study. Data were coded by hands and structured in the form of tables in accordance with 7 codes categorized in 2 themes. Coded data were interpreted to investigate the research questions by using the inductive method. Result & Conclusions: This study found that live chat and e-service quality in E-CRM directly affect how satisfied a customer feel with a company in e-commerce, thus affecting trust as well. However, the findings also showed that not all customers could perceive all the effects of E-CRM on their satisfaction and trust. Suggestions for future research: Other features such as electronic word-of-mouth, internet branding or internet prices are suggested for the future research to have an in-depth understanding of E-CRM effects. Future studies may combine data from both company and customers to increase the validity and reliability. Furthermore, the population of samples could be collected in others cities or countries than in Gävle, Sweden to generalize the result more. The contribution of the thesis: This study contributes knowledge about E-CRM effects in Swedish e-commerce. Some differences related to existing theories were found in this research such as the effects of gender on trust or effects of prices on relationship building. Understanding the customer perspectives on E-CRM effects enables companies to have a proper E-CRM implementation and training for their organization and employees.

Published
2017

100. Consumer behavior in coffee drinking : Comparison between Chinese and Swedish university students

Author

Yan, Min and Li, Qiuyun

Subjects
purchase process, coffee drinking, consumption characteristic, Consumer behavior, Business Administration, Företagsekonomi
Abstract

The aim of this study is to analyze factors that affecting consumers to drink coffee, based on two case studies in University of Gävle in Sweden and Zhuhai College of Jilin University in China.The study was conducted with mixed research methods. A questionnaire survey was designed as a pre-study to get a general idea and the interviews were designed based on the result of survey in order to gain more detailed information and explanations from the respondents. All the data are shown by tables or diagrams or histograms. University students in two different culture participated in survey and interviews, a comparison perspective for cross culture was mentioned in this study. As for Result & Conclusions, both external factors (culture, price and people around) as well as internal factors (personality, psychological influence, learning and knowledge) impact the consumer‟s behaviors that are shown in different consumption characteristics. Take all in account, these factors could have an effect on university students to drink (or not drink) coffee in Jilin University and University of Gävle. And Contribution & implication, the comparison of coffee drink between Chinese culture and Swedish culture is the most attractive contributions, supplementing the related study. Price issue was considered as the important factor that affecting the consumer to choose coffee, thus suggesting the managers to focus on the coffee price. In addition, the effective way to explore coffee market in China or Sweden is to know better of the consumers. Suggestions for future research, other consumer groups are missing given the study only focus on the university students. Also tested with more sample sizes of survey andIIinterviews are recommended in the future research so as to make it even valid and reliable.

Published
2016

Catalog

Books, media, physical & digital resources
See catalog results