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308 results on '"Li, Pei-Pei"'

53. Additional file 1 of Socioeconomic disparities and infancy growth trajectory: a population-based and longitudinal study

Author

Shao, Zi-yu, Wang, Peng, Li, Pei, Sun, Yu, Li, Pei-pei, and Zhu, Peng

Abstract

Additional file 1: Supplemental Table 1. Model comparison indices for models withdifferent number of latent classes. Supplemental Table 2. Regressioncoefficients (95% confidence intervals) of predictorsforBMI z scores in infants with low birth weight in Model 2. Supplemental Table 3. Trajectoriesof BMI z scores in high and low SES separated by normal birth weightand low birth weight.

Published
2021
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57. Structural Reliability Analysis without Exclusion of the Distribution Parameter Uncertainties

Author

Zhao, Yan-Gang, Li, Pei-Pei, and Lu, Zhao-Hui

Subjects
Point-estimate method, Cubic normal distribution, Conditional reliability index
Abstract

会議名/ Conference Name : APSSRA2020, 回次 / Conference Sequence : 7, 開催期間 / Conference Date : October 4-7, 2020, 開催会場 / Conference Venue : The University of Tokyo, 開催地 / Conference Place : Tokyo, 開催国 / Conference Country : JPN

Published
2020

58. Evaluation of the Structural Reliability under Imperfect Knowledge of Distribution Parameters

Author

LI, PEI-PEI, ZHAO, YAN-GANG, and LU, ZHAO-HUI

Subjects
Conditional failure probability, Point-estimate method, Conditional reliability index
Abstract

会議名/ Conference Name : APSSRA2020, 回次 / Conference Sequence : 7, 開催期間 / Conference Date : October 4-7, 2020, 開催会場 / Conference Venue : The University of Tokyo, 開催地 / Conference Place : Tokyo, 開催国 / Conference Country : JPN

Published
2020

67. Rare taxa maintain the stability of crop mycobiomes and ecosystem functions

Author

Xiong, Chao, primary, He, Ji‐Zheng, additional, Singh, Brajesh K., additional, Zhu, Yong‐Guan, additional, Wang, Jun‐Tao, additional, Li, Pei‐Pei, additional, Zhang, Qin‐Bing, additional, Han, Li‐Li, additional, Shen, Ju‐Pei, additional, Ge, An‐Hui, additional, Wu, Chuan‐Fa, additional, and Zhang, Li‐Mei, additional

Published
2020
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68. Host selection shapes crop microbiome assembly and network complexity

Author

Xiong, Chao, primary, Zhu, Yong‐Guan, additional, Wang, Jun‐Tao, additional, Singh, Brajesh, additional, Han, Li‐Li, additional, Shen, Ju‐Pei, additional, Li, Pei‐Pei, additional, Wang, Gui‐Bao, additional, Wu, Chuan‐Fa, additional, Ge, An‐Hui, additional, Zhang, Li‐Mei, additional, and He, Ji‐Zheng, additional

Published
2020
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74. Additional file 2: of Protist communities are more sensitive to nitrogen fertilization than other microorganisms in diverse agricultural soils

Author

Zhao, Zhi-Bo, Ji-Zheng He, Geisen, Stefan, Han, Li-Li, Wang, Jun-Tao, Ju-Pei Shen, Wei, Wen-Xue, Fang, Yun-Ting, Li, Pei-Pei, and Zhang, Li-Mei

Subjects
fungi
Abstract

Details regarding network analyses to assess seasonal dynamics of soil microbiome associations and SEM to determine the importance abiotic factors and biotic factors on the significant reductions in the alpha diversity of the protist community. (DOCX 39 kb)

Published
2019
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75. Additional file 1: of Protist communities are more sensitive to nitrogen fertilization than other microorganisms in diverse agricultural soils

Author

Zhao, Zhi-Bo, Ji-Zheng He, Geisen, Stefan, Han, Li-Li, Wang, Jun-Tao, Ju-Pei Shen, Wei, Wen-Xue, Fang, Yun-Ting, Li, Pei-Pei, and Zhang, Li-Mei

Abstract

Figure S1. Relative abundance of taxonomic composition of soil bacterial (A), fungal (B), and protist (C) community at phylum level, at class level, and at phylum level, respectively. Figure S2. LEfSe results revealed bacterial biomarkers (from phylum to genus level) sensitive to nitrogen fertilizers (no nitrogen addition (control) or nitrogen addition (N) or nitrogen + straw addition (NS)). Figure S3. LEfSe results revealed fungal biomarkers (from phylum level to genus level) sensitive to nitrogen fertilizers (no nitrogen addition (control) or nitrogen addition (N) or nitrogen + straw addition (NS)). Figure S4. Networks visualizing seasonal changes in co-occurrence patterns among protist, bacterial, and fungal taxa at family level across all soils in black soil, fluvo-aquic soil, and red soil, respectively. Figure S5. Beta-diversity of bacterial, fungal, and protist communities in each soil type under summer and autumn season, visualized by nonmetric multidimensional scaling (NMDS) based on unweighted unifrac phylogenetic distance metrics at OTU level. Figure S6. Putative key hubs in each network identified by betweenness centrality (BC) and closeness centrality (CC) of each node. Figure S7. Geographic location of three field experiment sites in China and diagram of fertilization and sampling arrangements. Table S1. Information of primers used in this study. Table S2. Physicochemical properties of the examined soil. Table S3. Bacterial biomarkers sensitive to nitrogen fertilizer treatments revealed by LEfSe analysis. Table S4. Fungal biomarkers sensitive to nitrogen fertilizer treatments revealed by LEfSe analysis. Table S5. Protist biomarkers sensitive to nitrogen fertilizer treatments revealed by LEfSe analysis. Table S6. Spearman correlations between alpha diversity of microbiomes and physicochemical properties in soils. Table S7. Node information of edges appearing in at least two networks linking protist to bacterial or fungal taxa in Fig. 3. Table S8. Topological indices used in this study for each network in Figure S4. Table S9. Nodes information of edges appearing in at least two networks linking protist to bacterial or fungal taxa in Figure S4. Table S10. The taxonomic information of protist nodes in Table 5. (DOCX 2031 kb)

Published
2019
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78. Rare taxa maintain the stability of crop mycobiomes and ecosystem functions.

Author

Xiong, Chao, He, Ji‐Zheng, Singh, Brajesh K., Zhu, Yong‐Guan, Wang, Jun‐Tao, Li, Pei‐Pei, Zhang, Qin‐Bing, Han, Li‐Li, Shen, Ju‐Pei, Ge, An‐Hui, Wu, Chuan‐Fa, and Zhang, Li‐Mei

Subjects
BIOTIC communities, FUNGAL communities, ECOSYSTEMS, SOIL enzymology, CROP yields, CORN growth, BARLEY
Abstract

Summary: Plants harbour highly diverse mycobiomes which sustain essential functions for host health and productivity. However, ecological processes that govern the plant–mycobiome assembly, interactions and their impact on ecosystem functions remain poorly known. Here we characterized the ecological role and community assembly of both abundant and rare fungal taxa along the soil–plant continuums (rhizosphere, phyllosphere and endosphere) in the maize–wheat/barley rotation system under different fertilization practices at two contrasting sites. Our results indicate that mycobiome assembly is shaped predominantly by compartment niche and host species rather than by environmental factors. Moreover, crop‐associated fungal communities are dominated by few abundant taxa mainly belonging to Sordariomycetes and Dothideomycetes, while the majority of diversity within mycobiomes are represented by rare taxa. For plant compartments, the abundant sub‐community is mainly determined by stochastic processes. In contrast, the rare sub‐community is more sensitive to host selection and mainly governed by deterministic processes. Furthermore, our results demonstrate that rare taxa play an important role in fungal co‐occurrence network and ecosystem functioning like crop yield and soil enzyme activities. These results significantly advance our understanding of crop mycobiome assembly and highlight the key role of rare taxa in sustaining the stability of crop mycobiomes and ecosystem functions. [ABSTRACT FROM AUTHOR]

Published
2021
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79. Host selection shapes crop microbiome assembly and network complexity.

Author

Xiong, Chao, Zhu, Yong‐Guan, Wang, Jun‐Tao, Singh, Brajesh, Han, Li‐Li, Shen, Ju‐Pei, Li, Pei‐Pei, Wang, Gui‐Bao, Wu, Chuan‐Fa, Ge, An‐Hui, Zhang, Li‐Mei, and He, Ji‐Zheng

Subjects
SUSTAINABLE agriculture, CROP management, WHEAT, ECOSYSTEM health, CROPS, BARLEY
Abstract

Summary: Plant microbiomes are essential to host health and productivity but the ecological processes that govern crop microbiome assembly are not fully known.Here we examined bacterial communities across 684 samples from soils (rhizosphere and bulk soil) and multiple compartment niches (rhizoplane, root endosphere, phylloplane, and leaf endosphere) in maize (Zea mays)‐wheat (Triticum aestivum)/barley (Hordeum vulgare) rotation system under different fertilization practices at two contrasting sites.Our results demonstrate that microbiome assembly along the soil‐plant continuum is shaped predominantly by compartment niche and host species rather than by site or fertilization practice. From soils to epiphytes to endophytes, host selection pressure sequentially increased and bacterial diversity and network complexity consequently reduced, with the strongest host effect in leaf endosphere. Source tracking indicates that crop microbiome is mainly derived from soils and gradually enriched and filtered at different plant compartment niches. Moreover, crop microbiomes were dominated by a few dominant taxa (c. 0.5% of bacterial phylotypes), with bacilli identified as the important biomarker taxa for wheat and barley and Methylobacteriaceae for maize.Our work provides comprehensive empirical evidence on host selection, potential sources and enrichment processes for crop microbiome assembly, and has important implications for future crop management and manipulation of crop microbiome for sustainable agriculture. [ABSTRACT FROM AUTHOR]

Published
2021
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88. Metadherin interference inhibits proliferation and enhances chemo-sensitivity to doxorubicin in diffuse large B cell lymphoma

Author

Li, Pei-Pei, Feng, Li-Li, Chen, Na, Lu, Kang, Meng, Xiao-Hui, Ge, Xue-Ling, Lv, Xiao, and Wang, Xin

Subjects
immune system diseases, hemic and lymphatic diseases, Original Article
Abstract

Metadherin (MTDH) is highly expressed in many tumors and is involved in the proliferation, metastasis and drug resistance of tumor cells by regulating multiple signaling pathways. Our previous studies demonstrated that MTDH is overexpressed in diffuse large B cell lymphoma (DLBCL) and involved in apoptosis resistance, in part, via Wnt signaling. Here, we investigated the role of MTDH in the chemo-sensitivity of DLBCL. The study was performed in the DLBCL cell line LY8 to investigate the relationship between MTDH expression and doxorubicin (DOX) sensitivity in DLBCL. A MTDH interference model was developed in LY8 cells by transfected with lentivirus which is carrying MTDH interference sequence. Western blot was used to detect the protein expression. A CCK-8 assay was used to evaluate cell proliferation. The results showed that DOX treatment had no effect on the intracellular MTDH expression of LY8 cells. The proliferation of LY8 cells was inhibited after MTDH interference. MTDH interference increased the DOX sensitivity in the LY8 cell lines. The results suggested that MTDH is a potential therapeutic target in DLBCL, and it cooperates with DOX in treatment of DLBCL.

Published
2014

97. Protective effects of atorvastatin on cerebral vessel autoregulation in an experimental rabbit model of subarachnoid hemorrhage.

Author

Chen, Jun-Hui, Wu, Ting, Yang, Li-Kun, Chen, Lei, Zhu, Jie, Li, Pei-Pei, Hu, Xu, and Wang, Yu-Hai

Subjects
ATORVASTATIN, OSTEOPOROSIS, BONE resorption, OSTEOCLASTS, LABORATORY rabbits
Abstract

The aim of the present study was to assess the therapeutic effects of atorvastatin on cerebral vessel autoregulation and to explore the underlying mechanisms in a rabbit model of subarachnoid hemorrhage (SAH). A total of 48 healthy male New Zealand rabbits (weight, 2-2.5 kg) were randomly allocated into SAH, Sham or SAH + atorvastatin groups (n=16/group). The Sham group received 20 mg/kg/d saline solution, whereas 20 mg/kg/d atorvastatin was administered to rabbits in the SAH + atorvastatin group following SAH induction. Changes in diameter, perimeter and basilar artery (BA) area were assessed and expression levels of the vasoactive molecules endothelin-1 (ET-1), von Willebrand factor (vWF) and thrombomodulin (TM) were measured. Neuronal apoptosis was analyzed 72 h following SAH by terminal deoxynucleotidyl-transferase-mediated dUTP nick-end labeling (TUNEL) staining. The mortality rate in the SAH group was 18.75, 25% in the SAH + atorvastatin treated group and 0% in the Sham group (n=16/group). The neurological score in the SAH + atorvastatin group was 1.75±0.68, which was significantly higher compared with the Sham group (0.38±0.49; P<0.05). The BA area in the SAH + atorvastatin group (89.6±9.11) was significantly lower compared with the SAH group (115.4±11.0; P<0.01). The present study demonstrated that SAH induction resulted in a significant increase in the diameter, perimeter and cross-sectional area of the BA in the SAH + atorvastatin group. Administration of atorvastatin may significantly downregulate the expression levels of ET-1, vWF and TM (all P<0.01) vs. sham and SAH groups. TUNEL staining demonstrated that neuronal apoptosis was remarkably reduced in the hippocampus of SAH rabbits following treatment with atorvastatin (P<0.05). Atorvastatin treatment may alleviate cerebral vasospasm and mediate structural and functional remodeling of vascular endothelial cells, in addition to promoting anti-apoptotic signaling. These results provided supporting evidence for the use of atorvastatin as an effective and well-tolerated treatment for SAH in various clinical settings and may protect the autoregulation of cerebral vessels. [ABSTRACT FROM AUTHOR]

Published
2018
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