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51. Estudio de mejora de la calidad del agua para el olivar de riego de provincia de Jaén mediante la aplicación de herramientas SIG

Author

Universidad de Sevilla. Departamento de Ciencias Agroforestales, Pérez Latorre, F. J., Peragón, J.M., Delgado García, Antonio, Universidad de Sevilla. Departamento de Ciencias Agroforestales, Pérez Latorre, F. J., Peragón, J.M., and Delgado García, Antonio more...

Abstract

El objetivo de este trabajo es el estudio, por medio de SIG, de la viabilidad de la utilización conjunta para el riego de olivar de aguas superficiales y subterráneas, para disminuir la salinización de acuíferos y los riesgos de contaminación por retornos de agua en la provincia de Jaén (sur de España). Se procede a evaluar las proporciones óptimas de los dos tipos de agua en función al umbral de salinidad a partil del cual puede afectar a la producción de la cosecha de olivar, y realizar mapas temáticos con el fin de evitar una acumulación excesiva de sal en el suelo. Se consideraron diferentes variables de la evaluación de riesgos, y un mapa temático para cada variable desarrollado por medio de análisis geoestadístico de los datos, utilizando el software de código abierto gvSIG. La herramienta basada en GIS fue una estrategia capaz de realizar mapas de mezcla de agua superficial y subterránea para disminuir los riesgos de salinización. Con este trabajo se expone la posibilidad de solucionar la afección de las superficies regadas en sus cuencas vertiente, desde las que la escorrentía superficial puede arrastrar sustancias contaminantes hacia áreas permeables a las que recarga, mediante la mezcla de agua de distinta procedencia, minimizando el riesgo de afección y vulnerabilidad de las escorrentías superficiales y aguas subterráneas frente a la contaminación. more...

Published
2016

53. DEVELOPMENT OF THE TOXICOLOGY SECTION OF THE AMERICAN HEART ASSOCIATION'S (AHA) GUIDELINES 2000 FOR CARDIOPULMONARY RESUSCITATION AND EMERGENCY CARDIOVASCULAR CARE (ECC)

Author

Martin, TG, de Latorre, F, Ross, MP, Albertson, TE, Dawson, A, Hoffman, RS, Hollander, JE, Jaeger, A, and Kerns, W

Subjects
CPR (First aid) -- Standards, Poisoning -- Care and treatment, Environmental issues, Health, Pharmaceuticals and cosmetics industries, American Heart Association -- Standards
Abstract

Background: The evidence- and consensus-based development of these published guidelines for poisoned patients will be reviewed.[1] The scarcity of RCT on these topics made an exclusively evidence-based evaluation impossible. This work highlights the need for properly designed clinical studies in developing medical toxicology treatment guidelines. The following topics, evidence overview and recommendations will be discussed. Use of alpha- and beta-adrenergic receptor antagonists in the management of cocaine-associated, acute coronary syndrome (Coc-ACS): The reviewed evidence consisted of 2 randomized clinical trials (RCT) of very good quality, 1 prospective study and 4 cath lab studies of very good to excellent quality, three case series of poor to fair quality and 4 animal studies of good to excellent quality. Recommendations: First line therapies of Coc-ACS include nitrates and benzodiazepines. The use of an alpha-adrenergic receptor antagonist (i.e. phentolamine) should be considered in Coc-ACS patients refractory to vigorous nitrate and benzodiazepine therapy. The use of non-selective beta-adrenergic receptor blockers (i.e. propranolol) is contraindicated in Coc-ACS. Non-selective beta-adrenergic receptor blockers may worsen cocaine induced hypertension and/or coronary vasoconstriction. The use of selective beta-adrenergic receptor blockers (i.e. esmolol and metoprolol) and mixed alpha/beta-adrenergic receptor blockers (i.e. labetalol) are not recommended in Coc-ACS. Use of bicarbonate, lidocaine, propranolol and epinephrine in cocaine-associated, ventricular tachycardia or fibrillation (Coc-VT/VF): For bicarbonate in Coc-VT, two very small case series of good quality and 7 animal studies of fair to good quality were reviewed with most addressing the electrophysiological effects and only one specifically addressing Coc-VT. For lidocaine in Coc-VT, one retrospective clinical study of good quality and 5 animal studies of fair to good quality were reviewed with most addressing the electrophysiological effects and only one specifically addressing Coc-VT. On the safety of lidocaine when given in cocaine toxicity, three animal studies were reviewed. For propranolol in Coc-VT/ VF, 2 animal studies of good quality were reviewed with both addressing ventricular arrhythmias. There were no studies of the efficacy of epinephrine in Coc-VF. Recommendations: First-line drug therapies for hemodynamically stable Coc-VT or refractory Coc-VF are sodium bicarbonate and lidocaine. The use of non-selective beta-adrenergic receptor blockers (i.e. propranolol) is contraindicated in Coc-VT. Use of calcium in calcium channel blocker (CCB) and beta-blocker (BB) poisoning: Evidence evaluated included 2 case series of fair to very good quality, 10 animal studies of good to excellent quality and numerous case reports concerning the use of calcium in CCB poisoning. There are more than 130 published case reports on the use of calcium in calcium channel blocker poisoning. Because multiple treatments were usually attempted and severity of poisoning quite varied, it was impossible to reach definitive conclusions from them. Recommendations: First-line drug therapy for calcium channel blocker CCB drug-induced shock (DI shock) remains catecholamine type vasopressors. Calcium chloride infusions (1-3 gm slow IV push) are recommended in CCB-induced shock refractory to conventional catecholamine vasopressor therapy. Additional calcium infusions via bolus or constant infusion would be warranted in patients demonstrating a beneficial hemodynamic response to the initial calcium infusions. Calcium infusions may be beneficial in other types of drug induced (DI) shock but cannot be recommended because of limited supportive data. Use of insulin euglycemia in CCB and BB poisoning: Evidence reviewed included 1 small case series of fair quality and 8 animal studies that were of very good to excellent quality. Recommendation: Insulin-euglycemia '-pump or -clamp' therapy may be beneficial in CCB-DI shock and BB-DI shock but cannot be recommended because of limited supportive data. Timing of assisted ventilation and dose of naloxone in opiate-induced respiratory failure: There were no articles, which compared the safety and efficacy of naloxone reversal of opioid overdose before or after the initiation of artificial ventilation. The impact of naloxone therapy on blood catecholamine levels was evaluated in two prospective human trials of good quality and four animal studies of good to very good quality. Four cases series of good to very good quality were reviewed for data on efficacy and safety of opioid reversal in ECC. Recommendation: Assisted ventilation and reversal with an opioid antagonist, such as naloxone, should be attempted as soon as possible and prior to intubation in patients with a palpable pulse. Naloxone therapy need not be withheld until assisted ventilations have begun. In opioid dependent patients, a lower initial dose of naloxone (i.e. 0.1-0.2 mg IV, repeated until 0.4 mg) is preferable to a larger initial dose (i.e. 2.0 mg IV). When an opioid overdose is suspected, one should not conclude that the patient was unresponsive until a total naloxone dose of 4-6 mg has been given. Systemic alkalosis in tricyclic antidepressant (TCA) poisoning: The evidence supporting the proposal consisted of four case series (n = 3, 4, 5 and 91) that were of good quality and 24 animal or in vitro studies that were of good to excellent quality. There was one small case report (n = 2) of fair quality with questionable opposing evidence. The numerous published individual cases reporting beneficial effects of systemic alkalosis in TCA poisoning were not included in this review. Recommendation: Sodium bicarbonate is the drug of choice for ventricular dysrhythmias and/or shock due to tricyclic antidepressant (TCA) poisoning. The beneficial effects of sodium bicarbonate result from systemic alkalosis and hypertonic sodium effects. More rapid systemic alkalosis may be achieved via hyperventilation but further benefit often results from the hypertonic sodium. In cases of serious TCA-induced CV toxicity, the goal is a systemic pH of 7.50-7.55. Intermittent bolus sodium bicarbonate administration is preferable to a constant infusion until the desired pH is attained. Procainamide for TCA-induced ventricular dysrhythmias: The panel members could find very little evidence on the use of procainamide in TCA-induced VT/VF. Reports of use in one dog and two rabbits and two case reports were reviewed. Recommendation: When TCA-VT/VF is resistant to sodium bicarbonate, lidocaine is the antiarrhythmic of choice. The use of procainamide for TCA-VT/VF is contraindicated. Because both procainamide and TCA have class Ia antiarrhythmic properties, procainamide would be expected to worsen TCA CV toxicity. Use of high dose vasopressors in DI shock in cases refractory to conventional therapy: Evidence supporting high dose vasopressors consisted 9 case reports of very good quality. Two animal that were either neutral or opposing were of good quality. Recommendation: In DI-shock refractory to conventional therapy, high dose vasopressors may be life saving. While most patients with refractory DI shock have a very low systemic vascular resistance (SVR), some patients have a very high SVR. Therefore, central hemodynamic monitoring should be implemented in patients with DI shock refractory to high dose vasopressors. In most cases vasopressors may be rapidly titrated until shock is adequately treated or recurrent ventricular dysrhythmias, signs of severe peripheral vasoconstriction or an excessively high SVR is observed. Use of circulatory assist devices (IABP or emergency bypass) in DI-shock refractory to maximal medical therapy: Evidence supporting the use of cardiopulmonary bypass consisted of 6 animal studies of very good quality and more than 30 case reports. Evidence supporting the use of the intra-aortic balloon pump consisted of 1 animal study of fair quality and more than 10 case reports. Recommendation: Circulatory assist devices may be live saving in DI-shock refractory to maximal medical therapy. If these heroic measures are to be effective, they must be implemented before the stage of irreversible shock has been reached. Early implementation usually requires advanced planning and approval from multiple disciplines including cardiology, cardiothoracic surgery and cardiopulmonary perfusion. Reference: [1] Circ 2000;102(suppl I):223-228., Martin TG, Latorre F de, Ross MP, Albertson TE, Dawson A, Hoffman RS, Hollander JE, Jaeger A, Kerns W. UW Medical Toxicology Program, University of Washington Medical Center, Seattle, Washington, [...] more...

Published
2001

54. Tratamiento del hiperparatiroidismo primario mediante abordaje mínimamente invasivo

Author

Alicia Calero A, Marivi Collado S, María Diez T, Raquel Latorre F, Roberto Rojo B, Augusto García V, Carmen Ramiro P, and Ana Belén Aláez C

Subjects
Hiperparatiroidismo primario, Surgery, abordaje unilateral
Abstract

El abordaje unilateral del hiperparatiroidismo primario constituye una opcion tecnica cada vez mas usada y apropiada debido a las caracteristicas de esta cirugia. Este tipo de abordaje ha sido posible por la aparicion del Tc sestamibi, de la subespecializacion de la cirugia y de la determinacion de la PTH intraoperatoria. A continuacion exponemos un estudio epidemiologico, descriptivo y retrospectivo desde enero de 2004 a diciembre de 2008. Durante este tiempo fueron intervenidos en el hospital Ramon y Cajal de Madrid un total de 195 enfermos por hiperparatiroidismo primario. De ellos, 140 fueron sometidos a exploracion unilateral por sospecha de adenoma unico. La correlacion entre los hallazgos gammagraficos y quirurgicos fue correcta en todos los casos (139) menos uno en cuanto a lo que a lateralidad se refiere. Fallo en 30 casos en los que se detecto mal la localizacion superior e inferior. En cuanto a los resultados, se extirpo el adenoma correctamente en 135 de los 140 pacientes. Asi podemos decir que la combinacion de la gammagrafia, de un cirujano con experiencia y el apoyo de la PTH intraoperatoria proporciona una elevada tasa de curacion en el caso de adenomas paratiroideos en el abordaje unilateral con una tasa de hipercalcemia recurrente o persistente entre el 3%-5%, tasa similar a la obtenida por cirujanos expertos al realizar una cervicotomia exploradora (considerada gold standard) pero con menor morbilidad postoperatoria, menor dolor y menor tiempo quirurgico. more...

Published
2011

55. Tratamiento del hiperparatiroidismo primario mediante abordaje mínimamente invasivo

Author

ALÁEZ C, ANA BELÉN, RAMIRO P, CARMEN, CALERO A, ALICIA, LATORRE F, RAQUEL, DÍEZ T, MARÍA, ROJO B, ROBERTO, COLLADO S, MARIVI, and GARCÍA V, AUGUSTO

Subjects
Hiperparatiroidismo primario, unilateral boarding, Primary hiperparatiroidism, abordaje unilateral
Abstract

El abordaje unilateral del hiperparatiroidismo primario constituye una opción técnica cada vez más usada y apropiada debido a las características de esta cirugía. Este tipo de abordaje ha sido posible por la aparición del Tc sestamibi, de la subespecialización de la cirugía y de la determinación de la PTH intraoperatoria. A continuación exponemos un estudio epidemiológico, descriptivo y retrospectivo desde enero de 2004 a diciembre de 2008. Durante este tiempo fueron intervenidos en el hospital Ramón y Cajal de Madrid un total de 195 enfermos por hiperparatiroidismo primario. De ellos, 140 fueron sometidos a exploración unilateral por sospecha de adenoma único. La correlación entre los hallazgos gammagráficos y quirúrgicos fue correcta en todos los casos (139) menos uno en cuanto a lo que a lateralidad se refiere. Falló en 30 casos en los que se detectó mal la localización superior e inferior. En cuanto a los resultados, se extirpó el adenoma correctamente en 135 de los 140 pacientes. Así podemos decir que la combinación de la gammagrafía, de un cirujano con experiencia y el apoyo de la PTH intraoperatoria proporciona una elevada tasa de curación en el caso de adenomas paratiroideos en el abordaje unilateral con una tasa de hipercalcemia recurrente o persistente entre el 3%-5%, tasa similar a la obtenida por cirujanos expertos al realizar una cervicotomía exploradora (considerada gold standard) pero con menor morbilidad postoperatoria, menor dolor y menor tiempo quirúrgico. The unilateral boarding of the primary hiperparatiroidism constitutes a technical option increasingly secondhand and adapted for the characteristics of this surgery. This type of boarding has been possible for the appearance of the Tc sestamibi, of the subspecialization of the surgery and of the determination of the PTH intraoperatory. Later we expose an epidemiological, descriptive and retrospective study from january 2004 to december 2008. During this time there were controlled in the hospital Ramon and Cajal of Madrid a total of 195 patients for primary hiperparatiroidism. Of them, 140 were submitted to unilateral exploration by suspicion of the solitary adenoma. The correlation between the findings of Tc sestamibi and surgical was correct in all the cases (139) except one concerns to right or left side. It failed in 30 cases in which there was detected badly the top and low location. As for the results the adenoma was extirpated correctly in 135 of 140 patients. This way we can say that the combination of the gammagraphy, a surgeon with experience and the support of the PTH intraoperatory they meet a high rate of treatment in case of adenomas in the unilateral boarding on a rate of hipercalcemia appellant or persistently between 3%-5%, rate similar to the obtained one for expert surgeons on having fulfilled an exploratory cervicotomy (considered "gold standard") but with minor postoperatory morbidity, minor pain and minor surgical time. more...

Published
2011

56. Influencia de los hábitos de la población adolescente sobre la autoimagen y el riesgo de trastorno de la conducta alimentaria

Author

Vara Robles, E., Pons Grau, R., Lajara Latorre, F., Mónica Molina, S., Parrón Lagunas, L., and Porras Benjumea, R.

Subjects
Habits, Body image, Adolescent, Hábitos, Eating disorders, Imagen corporal, Trastornos de la alimentación, Deporte, Índice de masa corporal, Adolescentes, Sports, Body Mass Index
Abstract

Objetivo: valorar el entorno familiar y los hábitos de la población adolescente de nuestra área para detectar posibles factores asociados con alteraciones de la autoimagen o un mayor riesgo de presentar un trastorno de la alimentación. Material y métodos: 158 entrevistas a adolescentes que cursaban 1.º y 2.º de Enseñanza Secundaria Obligatoria, recogiendo sexo, edad, entorno familiar y social, horas de pantallas y contenidos, horas de deporte, horas de lectura y contenidos, autoimagen, test de actitud ante la alimentación (EAT-26) y somatometría. Resultados: el análisis de regresión logística mostró una asociación estadísticamente significativa entre la autoimagen correcta y las horas de deporte practicado (B = 0,11; p = 0,047), el hecho de tener hermanos (B = -1,4; p = 0,019), la puntuación total en el EAT-26 (B = -0,06; p = 0,005) y el índice de masa corporal (B = -0,1; p = 0,031). Conclusiones: el fomento del ejercicio físico y la difusión de ideas correctas sobre la imagen corporal pueden influir positivamente en una mejor autoimagen de la población adolescente y, del mismo modo, ayudar a prevenir posibles trastornos de la alimentación. Objetive: To evaluate familiar environment and habits of teenager population from our area to detect factors associated with alterations of self-image or an increased risk of presenting an eating disorder. Methods: One hundred and fifty-eight teenagers from first to second course of ESO (Obligatory Secondary Education) were interviewed collecting information about gender, age, family and social environment, time of screens viewing and contents, time of sport practicing, time of reading and contents, self-image, Eating Attitudes Test (EAT-26) and anthropometry. Results: The logistic regression showed a statistically significant association between self-image and time of sport practicing (B = 0.11; p = 0.047), having brothers (B =-1.4; p = 0.019), total punctuation on EAT-26 (B =-0.06; p = 0.005) and Body Mass Index (B =-0.1; p = 0.031). Conclusions: Promotion of sport practicing and healthy ideas about body image could improve teenager self-image and help to prevent the development of eating disorders. more...

Published
2011

58. Pseudoquiste de páncreas con extensión a mediastino

Author

María Diez T, Alicia Calero A, Purificación Calero G, Ana Belén Alaéz Ch, Joaquín Pérez D, Raquel Grajal M, Carmen Ramiro P, and Raquel Latorre F

Subjects
medicine.medical_specialty, Pancreatic pseudocyst, business.industry, medicine.medical_treatment, Pseudoquiste de páncreas, Mediastinum, medicine.disease, Chest pain, Gastrostomy, Surgery, Omental Bursa, medicine.anatomical_structure, medicine, Pancreatitis, Cyst, Radiology, medicine.symptom, mediastino, business, Mediastinal Cyst
Abstract

Pancreatic pseudocyst extended to the mediastinum. Case report We report a 53 years old male consulting for chest pain and dyspnea. On physical examination, an epigastric mass was detected. A TC scan showed a collection located in the omental bursa, which protruded over the posterior gastric wall and ascended to the mediastinum. Due to the presence of pancreatic calcifi ca- tions, a pancreatic pseudocyst was suspected. The mediastinal cyst was drained percutaneously, leaving pig tail drainage in the cavity. Afterwards a cyst excision and Roux en Y gastrostomy was performed. After the surgical procedure the cyst became infected, requiring antimicrobials. After two weeks he was discharged in good conditions. more...

Published
2011

59. Pseudoquiste de páncreas con extensión a mediastino

Author

Alaéz CH, Ana Belén, Ramiro P, Carmen, Calero A, Alicia, Diez T, María, Latorre F, Raquel, Grajal M, Raquel, Calero G, Purificación, and Pérez D, Joaquín

Subjects
Pseudocyst, Pseudoquiste de páncreas, pancreatitis, mediastino, mediastinum
Abstract

Los pseudoquistes de páncreas representan el 75% de las lesiones quísticas del páncreas y generalmente se circunscriben en el abdomen. Se presenta el caso de un paciente con un pseudoquiste de páncreas con extensión transhiatal a mediastino. Estos casos deben sospecharse mediante una historia clínica detallada y preguntando por antecedentes de dolor abdominal previo porque la clínica con la que se suelen manifestar es muy poco específica. El tratamiento de los pseudoquistes con extensión a mediastino debería ser el drenaje definitivo, bien de forma quirúrgica o endoscópica. We report a 53 years old male consulting for chest pain and dyspnea. On physical examination, an epigastric mass was detected. A TC scan showed a collection located in the omental bursa, which protruded over the posterior gastric wall and ascended to the mediastinum. Due to the presence of pancreatic calcifications, a pancreatic pseudocyst was suspected. The mediastinal cyst was drained percutaneously, leaving pig tail drainage in the cavity. Afterwards a cyst excision and Roux en Y gastrostomy was performed. After the surgical procedure the cyst became infected, requiring antimicrobials. After two weeks he was discharged in good conditions. more...

Published
2011

63. FRI0091 Arterial Stiffness Increases Thorough Time in Patients with Rheumatoid Arthritis. Factors Related to the Change

Author

Robustillo Villarino, M., primary, Rodilla Sala, E., additional, Gil Latorre, F., additional, Ybañez Garcia, M.D., additional, Martínez Ferrer, M.A., additional, Valls Pascual, È., additional, Vicens Bernabeu, E., additional, Vergara Dangond, C., additional, Alber Espí, G., additional, and Alegre Sancho, J.J., additional more...

Published
2015
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64. AB0372 Physical Exercise has no Influence on Markers of Subclinical Cardiovascular Disease in Patients with Rheumatoid Arthritis

Author

Robustillo Villarino, M., primary, Rodilla Sala, E., additional, Gil Latorre, F., additional, Ybañez Garcia, M.D., additional, Martínez Ferrer, M.A., additional, Valls Pascual, È., additional, Vicens Bernabeu, E., additional, Vergara Dangond, C., additional, Alber Espí, G., additional, and Alegre Sancho, J.J., additional more...

Published
2015
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65. SAT0127 Patients with Rheumatoid Arthritis Show Significantly Worse Subclinical Vascular Damage than Healthy and Hypertensive People

Author

Robustillo Villarino, M., primary, Rodilla Sala, E., additional, Gil Latorre, F., additional, Ybañez Garcia, M.D., additional, Martínez Ferrer, M.A., additional, Valls Pascual, È., additional, Vicens Bernabeu, E., additional, Vergara Dangond, C., additional, Alber Espí, G., additional, and Alegre Sancho, J.J., additional more...

Published
2015
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66. Impacto del abuso de pantallas sobre el desarrollo mental

Author

Vara Robles, E., Pons Grau, R., Lajara Latorre, F., Molina, S.M., Villarejo Romera, V., and Planas Sanz, E.

Subjects
Video games, Computer, Videojuegos, Televisión, Intelligence, Television, Ordenador, Índice de masa corporal, Niños, Children, Inteligencia, Body Mass Index
Abstract

Introducción: el presente estudio valora la antropometría, el desarrollo intelectual y las habilidades sociales de los niños según su exposición al abuso de pantallas (televisión, video-juegos, ordenador). Material y métodos: 130 entrevistas a niños entre 5 y 10 años recogiendo: sexo, edad, entorno familiar, horas de pantallas, horas de deporte, somatometría, puntuación del grado de responsabilidad y sociabilidad y test de Goodenough (como estimación del cociente intelectual). Resultados: los modelos de regresión lineal múltiple mostraron una asociación estadísticamente significativa entre el índice de masa corporal (IMC) y las horas de televisión y vídeos (B = 0,06; p = 0,05) y entre el IMC y las horas de ordenador y videojuegos (B = 0,34; p < 0,01), así como entre la estimación del cociente intelectual y las horas de ordenador y video-juegos (B = -1,67; p = 0,02). Conclusiones: deben desarrollarse estrategias para concienciar a las familias sobre los efectos perjudiciales del abuso de pantallas, tanto de los asociados al sedentarismo y a los contenidos negativos, como del daño sobre el desarrollo intelectual que produce el abuso de los juegos electrónicos. Objective: the present study examines anthropometric measurements, mental development and social skills in children exposed to screen-viewing (television, video games, computer). Methods: one hundred and thirty interviews were addressed to children aged 5 to 10 years. Information about gender, age, family, screen-viewing time, sport-practicing time, anthropometric measurements, responsibility punctuation, sociability punctuation and Goodenough's test (as estimation of intelligence quotient) was collected. Results: multiple regression models showed a statistically significant association between body mass index (BMI) and television and video viewing time (B = 0.06; p = 0.05) and between BMI and computer and videogame use time (B = 0.34; p < 0.01), as well as between estimated intelligence quotient and computer and video game use time (B = -1.67; p = 0.02). Conclusions: screen-viewing abuse is associated with a higher risk of overweight. Electronic games abuse is associated with a lower intelligence quotient. Wide strategies to warn families about these risks are needed. more...

Published
2009

67. [A prospective comparative study to assess the impact of pharmaceutical intervention in the promotion of sequential therapy with flouroquinolones]

Author

Manuel Pinteño-Blanco, Delgado Sánchez O, Escrivá Torralva A, Crespí Monjo M, Ventayol Bosch P, Puigventós Latorre F, and Martínez López I

Subjects
Male, Anti-Infective Agents, Injections, Intravenous, Administration, Oral, Humans, Female, Prospective Studies, Middle Aged, Pharmacy Service, Hospital, Drug Administration Schedule, Aged, Fluoroquinolones
Abstract

To assess the impact of pharmaceutical intervention on the use of sequential therapy (ST) with fluoroquinolones.A prospective comparative study of pharmaceutical intervention in two stages: observational stage and intervention stage for ST promotion.In all, 250 patients receiving intravenous therapy with fluoroquinolones (113 with levofloxacin and 137 with ciprofloxacin) were studied, with 76 and 70 patients, respectively, being eligible for a pharmaceutical intervention program to promote ST. Pharmaceutical intervention showed a decreased duration of intravenous therapy and increased duration of oral therapy for both drugs, as well as decreased medication-related costs, all in a statistically significant manner.ST promotion provides an opportunity to expand the role of hospital pharmacists and to optimize fluoroquinolone-based therapy, which results in decreased intravenous treatments and provides a more cost-effective option. more...

Published
2005

68. FRI0485 Long-Term Efficacy of Rituximab in Systemic Sclerosis. A Spanish Multicentric Analysis

Author

Alegre Sancho, J.J., primary, Narváez, J., additional, Castellví, I., additional, Herrera, S., additional, Molina, M., additional, Castillo, D., additional, Oller Rodríguez, J.E., additional, De la Morena Barrio, I., additional, Robustillo Villarino, M., additional, Valls Pascual, E., additional, Ybáñez García, D., additional, Martínez Ferrer, Ά., additional, Vicens Bernabéu, E., additional, Vergara Dangond, C., additional, Feced Olmos, C.M., additional, Llobet, J.M., additional, Nolla, J.M., additional, and Gil Latorre, F., additional more...

Published
2014
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69. FRI0057 Periodontal Disease and Functional Impairment in Rheumatoid Arthritis: Table 1

Author

Oller Rodríguez, J.E., primary, Ybáñez García, D., additional, Valls Pascual, E., additional, Silvestre Rangil, J., additional, Silvestre Donat, J., additional, De la Morena Barrio, I., additional, Vicens Bernabéu, E., additional, Vergara Dangond, C., additional, Martínez Ferrer, Ά., additional, Robustillo Villarino, M., additional, Alegre Sancho, J.J., additional, and Gil Latorre, F., additional more...

Published
2014
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70. SAT0163 Stratification of Cardiovascular Risk by Carotid Ultrasound in Patients with Rheumatoid Arthritis: Results of A Population from the EAST of Spain

Author

Robustillo-Villarino, M., primary, Alegre-Sancho, J.J., additional, Rodilla_Sala, E., additional, Gil-Latorre, F., additional, Martínez-Ferrer, À., additional, Ybañez-García, D., additional, Valls-Pascual, È., additional, De la Morena-Del Barrio, I., additional, Oller-Rodríguez, J.E., additional, Vicens-Bernabeu, E., additional, Vergara-Dangond, C., additional, and Feced-Olmos, C.M., additional more...

Published
2014
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71. FRI0083 Arterial Stiffness in Patients with Rheumatoid Arthritis. Value for Cardiovascular Risk Stratification

Author

Robustillo-Villarino, M., primary, Alegre-Sancho, J.J., additional, Gil-Latorre, F., additional, Rodilla-Sala, E., additional, Martínez-Ferrer, À., additional, Ybañez-García, D., additional, Valls-Pascual, È., additional, Feced-Olmos, C.M., additional, De la Morena-del Barrio, I., additional, Oller-Rodríguez, J.E., additional, Vergara Dangond, C., additional, and Vicens-Bernabeu, E., additional more...

Published
2014
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72. SAT0341 Immune Response to Hepatitis B Virus Vaccination in Patients with Spondyloarthritis Treated with Anti-TNF Therapy VS Hemodialyzed Patients

Author

Valls Pascual, E., primary, Fernández Matilla, M., additional, De La Morena Barrio, I., additional, Ybáñez García, D., additional, Molina Vila, P., additional, Feced Olmos, C., additional, Robustillo Villarino, M., additional, Gil Latorre, F., additional, Buch García, M.J., additional, Bautista Rentero, D., additional, Martínez Ferrer, À., additional, Oller Rodríguez, J.E., additional, Vicens Bernabeu, E., additional, Vergara Dangond, C., additional, and Alegre Sancho, J.J., additional more...

Published
2014
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73. Extracción asistida mediante litotricia extracorpórea de un catéter ureteral calcificado olvidado 2 años

Author

Millán Rodríguez, F., Rousaud Barón, F., Martí Malet, J., Izquierdo Latorre, F., and Rousaud Barón, A.

Subjects
Catéter ureteral, Calcificación, Ureteral stent, Extracorporeal wave lithotripsy, Litotricia extracorpórea, Calcification
Abstract

Se presenta el caso de un varón de 45 años que llevaba olvidado durante 2 años un catéter ureteral doble J izquierdo. El catéter presentaba ambos extremos calcificados no pudiéndose extraer mediante cistoscopia y pinzas. Se realizaron sesiones de litotricia extracorpórea en ambos extremos consiguiéndose la fragmentación de la litiasis y posteriormente pudo ser extraído en dos trozos mediante cistoscopia y ureteroscopia. A 45 year old man with a 2 year forgotten left double-pigtail ureteric stent was referred to our hospital. Because of distal calcifications, the stent could not be removed by means of a cystoscopy. So, extracorporeal wave lithotripsies were performed and then the stent were easily removed in two fragments by cystoscopy and ureteroscopy. more...

Published
2003

74. Neumomediastino y enfisema subcutáneo por perforación iatrogénica de colon

Author

Ghada Housari M, Natacha Apentchenko, Pedro Carda A, Javier Páramo Z, Francisca García-Moreno N, Mariana González Z, Raquel Latorre F, Teresa Pozancos, Sara Corral M, and Eduardo Lobo M

Subjects
Surgery
Abstract

En la radiografia de abdomen se evidencia impor-tante neumoperitoneo con desplazamiento caudal del higado, enfi sema subcutaneo y retroneumoperitoneo que dibuja la silueta del musculo Psoas (Figura 1). En la radiografia de torax importante neumoperito-neo y neumomediastino (Figura 2).La paciente es intervenida quirurgicamente de manera urgente mediante laparotomia exploradora donde se evidencia neoplasia de ciego perforada hacia retroperitoneo, importante enfi sema a nivel more...

Published
2011
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79. [Minimizing the costs of prescription of anti-infective drugs in two areas of primary health care]

Author

Castan Cameo S, Garcia Latorre F, Martinez Gorostiaga J, Sierra Moros M, Solano Bernad V, and Peral Casado A

Abstract

BACKGROUND: Pharmaceutical costs are the main cost item in basic health care. The need to contain health care expenditure has led to the search for alternatives in this area, one of which would be to foster a prescription policy which uses the cheapest presentation for each active principle. The aim of this study was to evaluate the amount which would be saved by prescribing the cheapest alternative from a selection of anti-infective drugs. METHODS: Pharmacy prescriptions in two different health areas were analyzed using the database on turnover of pharmaceutical products for 1995. Single principle drugs with anti-infective action were selected, and for each active principle and presentation the most economic alternative was sought using the records provided by the Ministry of Health and a cost minimisation analysis was undertaken. The cost of applying this prescription policy was not considered. RESULTS: Total pharmaceutical expenditure in the areas was pesetas 8.547 bn in 1995. Expenditure on selected anti-infective drugs was pesetas 522 million (6.1% of the total). The overall saving estimated was 7.63% (pesetas 39,901,778). This saving was centred on the following subgroups: penicillins, quinolones, cephalosporins and macrolides. Of potential savings identified, 75% would be achieved by prescribing the cheaper alternative of 2 active principles: amoxacillin and cyprofloxacine. CONCLUSIONS: The study shows the possibility of containing expenditure in our area and offers a basis for action in this direction. It would be advisable to increase information and training for prescribers and dispensers in order to stimulate the use of the most economical alternative of each medicament prescribed, especially in cases in which there are significant margins to be saved. more...

Published
1998

80. AB0829 Usefulness of cochin hand function score in spanish patients with systemic sclerosis

Author

Alegre-Sancho, J.J., primary, García de la Peña-Lefebvre, P., additional, Gil-Latorre, F., additional, Fernandez-Matilla, M., additional, Valero-Exposito, M., additional, Rodriguez-Rubio, S., additional, Amil-Casas, I., additional, Gonzalez-Martin, J., additional, Valls-Pascual, E., additional, Martinez-Ferrer, M.A., additional, Ybañez-Garcia, D., additional, Robustillo-Villarino, M., additional, Feced-Olmos, C.M., additional, and de la Morena-Barrio, I., additional more...

Published
2013
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81. AB0812 Usefulness of mouth handicap in systemic sclerosis scale in systemic sclerosis spanish patients

Author

Alegre-Sancho, J.J., primary, García de la Peña-Lefebvre, P., additional, Gil-Latorre, F., additional, Fernandez-Matilla, M., additional, Valls-Pascual, E., additional, Martinez-Ferrer, M.A., additional, Ybañez-Garcia, D., additional, Robustillo-Villarino, M., additional, Feced-Olmos, C.M., additional, de la Morena-Barrio, I., additional, Valero-Exposito, M., additional, Rodriguez-Rubio, S., additional, Amil-Casas, I., additional, and Gonzalez-Martin, J., additional more...

Published
2013
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82. FRI0378 Interleukin 6 and vascular disease in patients with systemic sclerosis

Author

Alegre-Sancho, J. J., primary, Robustillo-Villarino, M., additional, Zaragoza-Garcia, J. M., additional, Gil-Latorre, F., additional, Cubero-Tarin, V., additional, Feced-Olmos, C. M., additional, De la Morena Barrio, I., additional, Ybañez-Garcia, D., additional, Valls-Pascual, E., additional, Martinez-Ferrer, A., additional, Oller-Rodriguez, J. E., additional, Vicens-Bernabeu, E., additional, Rodilla-Sala, E., additional, and Tuzon-Segarra, M. T., additional more...

Published
2013
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100. Indagine idrologica sul fiume Galeso

Author

Cardellicchio N., Geraci S., Cavallo R.A., Annicchiarico C., Leone G., Marra C., Ragone P., and Latorre F.

Published
1993

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