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483 results on '"Krause, Bernd-J."'

52. Tolerability of [177Lu]Lu-PSMA-617 by treatment exposure in patients with metastatic castration-resistant prostate cancer (mCRPC): A VISION study subgroup analysis.

Author

Tagawa, Scott T., primary, Armstrong, Andrew J., additional, Krause, Bernd J., additional, Herrmann, Ken, additional, Rahbar, Kambiz, additional, De Bono, Johann S., additional, Adra, Nabil, additional, Desilvio, Michelle, additional, Messmann, Richard, additional, Holder, Geoffrey, additional, and Chi, Kim N., additional

Published
2022
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55. Olfactory Bulb D2/D3 Receptor Availability after Intrastriatal Botulinum Neurotoxin-A Injection in a Unilateral 6-OHDA Rat Model of Parkinson’s Disease

Author

Alberts, Teresa, primary, Antipova, Veronica, additional, Holzmann, Carsten, additional, Hawlitschka, Alexander, additional, Schmitt, Oliver, additional, Kurth, Jens, additional, Stenzel, Jan, additional, Lindner, Tobias, additional, Krause, Bernd J., additional, Wree, Andreas, additional, and Witt, Martin, additional

Published
2022
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58. DGN-Handlungsempfehlung (S1-Leitlinie) – PSMA-Liganden-PET/CT in der Diagnostik des Prostatakarzinoms – Stand: 01/2022 – AWMF-Registernummer: 031-055.

Author

Afshar-Oromieh, Ali, Eiber, Matthias, Fendler, Wolfgang, Schmidt, Matthias, Rahbar, Kambiz, Ahmadzadehfar, Hojjat, Umutlu, Lale, Hadaschik, Boris, Hakenberg, Oliver W., Fornara, Paolo, Kurth, Jens, Neels, O., Wester, Hans-Jürgen, Schwaiger, Markus, Kopka, Klaus, Haberkorn, Uwe, Herrmann, Ken, and Krause, Bernd J.

Published
2023
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64. List of Contributors

Author

Allegri, Ricardo F., primary, Arrighi, H. Michael, additional, Bagnati, Pablo M., additional, Bairu, Menghis, additional, Brucki, Sonia, additional, Burt, Tal, additional, Cheeseman, Lorne, additional, Chin, Richard, additional, Cote, Debbie N., additional, Cummings, Jeffrey, additional, Danandjaja, Stephanie, additional, Doraiswamy, P. Murali, additional, Emre, Murat, additional, Fan, James (Dachao), additional, Fujimoto, Yoko, additional, Grothe, Michel, additional, Gürvit, Ibrahim Hakan, additional, Guthrie, Spencer, additional, Hampel, Harald, additional, Hughes, Lynne, additional, Hüll, Michael, additional, İlbars, Hilal, additional, Iwatsubo, Takeshi, additional, Jones, Roy W., additional, Jose, Nadina C., additional, Kalali, Amir, additional, Kim, Seong Yoon, additional, Kivipelto, Miia, additional, Krause, Bernd J., additional, Kurth, Jens, additional, Li, Huafang, additional, Mangialasche, Francesca, additional, Möbius, Hans J., additional, Nitrini, Ricardo, additional, Ngandu, Tiia, additional, O’Byrne, Muriel, additional, Schüler, Peter, additional, Siegfried, Klaudius, additional, Spector, Sidney A., additional, Teipel, Stefan, additional, Üresin, Yağiz, additional, Weiner, Michael, additional, Yin, Jing, additional, and Zhong, Xue (Kate), additional

Published
2014
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65. Lutetium-177–PSMA-617 for Metastatic Castration-Resistant Prostate Cancer

Author

Sartor, Oliver, primary, de Bono, Johann, additional, Chi, Kim N., additional, Fizazi, Karim, additional, Herrmann, Ken, additional, Rahbar, Kambiz, additional, Tagawa, Scott T., additional, Nordquist, Luke T., additional, Vaishampayan, Nitin, additional, El-Haddad, Ghassan, additional, Park, Chandler H., additional, Beer, Tomasz M., additional, Armour, Alison, additional, Pérez-Contreras, Wendy J., additional, DeSilvio, Michelle, additional, Kpamegan, Euloge, additional, Gericke, Germo, additional, Messmann, Richard A., additional, Morris, Michael J., additional, and Krause, Bernd J., additional

Published
2021
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67. Impact of the COVID-19 pandemic on nuclear medicine departments in Europe

Author

Moreira, Ana Paula, primary, Jamar, François, additional, Ozcan, Zehra, additional, Piciu, Doina, additional, Als, Claudine, additional, Franceschi, Maja, additional, Trägårdh, Elin, additional, Zagar, Ivana, additional, Sowa-Staszczak, Anna, additional, Cachin, Florent, additional, Bennink, Roel, additional, Forrer, Flavio, additional, Adamsen, Tom Christian, additional, Fotopolous, Andreas, additional, Kalnina, Marika, additional, Jensen, Lars Thorbjørn, additional, Mussalo, Hanna, additional, Simanek, Milan, additional, Garcia-Cañamaque, Lina, additional, Nazarenko, Sergei, additional, Mihailovic, Jasna, additional, Bar-Sever, Zvi, additional, O’Connell, Martin, additional, Miladinova, Daniela, additional, Graham, Richard, additional, Giubbini, Raffaele, additional, Kaliská, Lucia, additional, Rozić, Damir, additional, Krause, Bernd J., additional, Gallowitsch, Hans-Jürgen, additional, Györke, Tamás, additional, Sediene, Severina, additional, Rumyantsev, Pavel, additional, Wadsak, Wolfgang, additional, and Kunikowska, Jolanta, additional

Published
2021
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69. Abnormal Regional and Global Connectivity Measures in Subjective Cognitive Decline Depending on Cerebral Amyloid Status

Author

Li, Shumei, Daamen, Marcel, Scheef, Lukas, Gaertner, Florian C., Buchert, Ralph, Buchmann, Martina, Buerger, Katharina, Catak, Cihan, Dobisch, Laura, Drzezga, Alexander, Ertl-Wagner, Birgit, Essler, Markus, Fliessbach, Klaus, Haynes, John Dylan, Incesoy, Enise Irem, Kilimann, Ingo, Krause, Bernd J., Lange, Catharina, Laske, Christoph, Priller, Josef, Ramirez, Alfredo, Reimold, Matthias, Rominger, Axel, Roy, Nina, Scheffler, Klaus, Maurer, Angelika, Schneider, Anja, Spottke, Annika, Spruth, Eike Jakob, Teipel, Stefan J., Tscheuschler, Maike, Wagner, Michael, Wolfsgruber, Steffen, Duzel, Emrah, Jessen, Frank, Peters, Oliver, Boecker, Henning, Li, Shumei, Daamen, Marcel, Scheef, Lukas, Gaertner, Florian C., Buchert, Ralph, Buchmann, Martina, Buerger, Katharina, Catak, Cihan, Dobisch, Laura, Drzezga, Alexander, Ertl-Wagner, Birgit, Essler, Markus, Fliessbach, Klaus, Haynes, John Dylan, Incesoy, Enise Irem, Kilimann, Ingo, Krause, Bernd J., Lange, Catharina, Laske, Christoph, Priller, Josef, Ramirez, Alfredo, Reimold, Matthias, Rominger, Axel, Roy, Nina, Scheffler, Klaus, Maurer, Angelika, Schneider, Anja, Spottke, Annika, Spruth, Eike Jakob, Teipel, Stefan J., Tscheuschler, Maike, Wagner, Michael, Wolfsgruber, Steffen, Duzel, Emrah, Jessen, Frank, Peters, Oliver, and Boecker, Henning

Abstract

Background: Amyloid-beta accumulation was found to alter precuneus-based functional connectivity (FC) in mild cognitive impairment (MCI) and Alzheimer's disease (AD) dementia, but its impact is less clear in subjective cognitive decline (SCD), which in combination with AD pathologic change is theorized to correspond to stage 2 of the Alzheimer's continuum in the 2018 NIA-AA research framework. Objective: This study addresses how amyloid pathology relates to resting-state fMRI FC in SCD, especially focusing on the precuneus. Methods: From the DELCODE cohort, two groups of 24 age- and gender-matched amyloid-positive (SCDA beta+) and amyloidnegative SCD (SCDA beta-) patients were selected according to visual [18F]-Florbetaben (FBB) PET readings, and studied with resting-state fMRI. Local (regional homogeneity [ReHo], fractional amplitude of low-frequency fluctuations [fALFF]) and global (degree centrality [DC], precuneus seed-based FC) measures were compared between groups. Follow-up correlation analyses probed relationships of group differences with global and precuneal amyloid load, as measured by FBB standard uptake value ratios (SUVRFBB). Results: ReHo was significantly higher (voxel-wise p < 0.01, cluster-level p < 0.05) in the bilateral precuneus for SCDA beta+ patients, whereas fALFF was not altered between groups. Relatively higher precuneus-based FC with occipital areas (but no altered DC) was observed in SCDA beta+ patients. In this latter cluster, precuneus-occipital FC correlated positively with global (SCDA beta+) and precuneus SUVRFBB (both groups). Conclusion: While partial confounding influences due to a higher APOE epsilon 4 carrier ratio among SCDA beta+ patients cannot be excluded, exploratory results indicate functional alterations in the precuneus hub region that were related to amyloid-beta load, highlighting incipient pathology in stage 2 of the AD continuum.

Published
2021

70. Impact of the COVID-19 pandemic on nuclear medicine departments in Europe.

Author

UCL - SSS/IREC/MIRO - Pôle d'imagerie moléculaire, radiothérapie et oncologie, UCL - (MGD) Service de médecine nucléaire, Moreira, Ana Paula, Jamar, François, Ozcan, Zehra, Piciu, Doina, Als, Claudine, Franceschi, Maja, Trägårdh, Elin, Zagar, Ivana, Sowa-Staszczak, Anna, Cachin, Florent, Bennink, Roel, Forrer, Flavio, Adamsen, Tom Christian, Fotopolous, Andreas, Kalnina, Marika, Jensen, Lars Thorbjørn, Mussalo, Hanna, Simanek, Milan, Garcia-Cañamaque, Lina, Nazarenko, Sergei, Mihailovic, Jasna, Bar-Sever, Zvi, O'Connell, Martin, Miladinova, Daniela, Graham, Richard, Giubbini, Raffaele, Kaliská, Lucia, Rozić, Damir, Krause, Bernd J, Gallowitsch, Hans-Jürgen, Györke, Tamás, Sediene, Severina, Rumyantsev, Pavel, Wadsak, Wolfgang, Kunikowska, Jolanta, UCL - SSS/IREC/MIRO - Pôle d'imagerie moléculaire, radiothérapie et oncologie, UCL - (MGD) Service de médecine nucléaire, Moreira, Ana Paula, Jamar, François, Ozcan, Zehra, Piciu, Doina, Als, Claudine, Franceschi, Maja, Trägårdh, Elin, Zagar, Ivana, Sowa-Staszczak, Anna, Cachin, Florent, Bennink, Roel, Forrer, Flavio, Adamsen, Tom Christian, Fotopolous, Andreas, Kalnina, Marika, Jensen, Lars Thorbjørn, Mussalo, Hanna, Simanek, Milan, Garcia-Cañamaque, Lina, Nazarenko, Sergei, Mihailovic, Jasna, Bar-Sever, Zvi, O'Connell, Martin, Miladinova, Daniela, Graham, Richard, Giubbini, Raffaele, Kaliská, Lucia, Rozić, Damir, Krause, Bernd J, Gallowitsch, Hans-Jürgen, Györke, Tamás, Sediene, Severina, Rumyantsev, Pavel, Wadsak, Wolfgang, and Kunikowska, Jolanta

Abstract

No abstract available

Published
2021

71. Impact of the COVID-19 pandemic on nuclear medicine departments in Europe

Author

Moreira, Ana Paula, Jamar, François, Ozcan, Zehra, Piciu, Doina, Als, Claudine, Franceschi, Maja, Trägårdh, Elin, Zagar, Ivana, Sowa-Staszczak, Anna, Cachin, Florent, Bennink, Roel, Forrer, Flavio, Adamsen, Tom Christian, Fotopolous, Andreas, Kalnina, Marika, Jensen, Lars Thorbjørn, Mussalo, Hanna, Simanek, Milan, Garcia-Cañamaque, Lina, Nazarenko, Sergei, Mihailovic, Jasna, Bar-Sever, Zvi, O’Connell, Martin, Miladinova, Daniela, Graham, Richard, Giubbini, Raffaele, Kaliská, Lucia, Rozić, Damir, Krause, Bernd J., Gallowitsch, Hans Jürgen, Györke, Tamás, Sediene, Severina, Rumyantsev, Pavel, Wadsak, Wolfgang, Kunikowska, Jolanta, Moreira, Ana Paula, Jamar, François, Ozcan, Zehra, Piciu, Doina, Als, Claudine, Franceschi, Maja, Trägårdh, Elin, Zagar, Ivana, Sowa-Staszczak, Anna, Cachin, Florent, Bennink, Roel, Forrer, Flavio, Adamsen, Tom Christian, Fotopolous, Andreas, Kalnina, Marika, Jensen, Lars Thorbjørn, Mussalo, Hanna, Simanek, Milan, Garcia-Cañamaque, Lina, Nazarenko, Sergei, Mihailovic, Jasna, Bar-Sever, Zvi, O’Connell, Martin, Miladinova, Daniela, Graham, Richard, Giubbini, Raffaele, Kaliská, Lucia, Rozić, Damir, Krause, Bernd J., Gallowitsch, Hans Jürgen, Györke, Tamás, Sediene, Severina, Rumyantsev, Pavel, Wadsak, Wolfgang, and Kunikowska, Jolanta

Published
2021

76. FDG PET and PET/CT: EANM procedure guidelines for tumour PET imaging: version 1.0

Author

Boellaard, Ronald, O’Doherty, Mike J., Weber, Wolfgang A., Mottaghy, Felix M., Lonsdale, Markus N., Stroobants, Sigrid G., Oyen, Wim J. G., Kotzerke, Joerg, Hoekstra, Otto S., Pruim, Jan, Marsden, Paul K., Tatsch, Klaus, Hoekstra, Corneline J., Visser, Eric P., Arends, Bertjan, Verzijlbergen, Fred J., Zijlstra, Josee M., Comans, Emile F. I., Lammertsma, Adriaan A., Paans, Anne M., Willemsen, Antoon T., Beyer, Thomas, Bockisch, Andreas, Schaefer-Prokop, Cornelia, Delbeke, Dominique, Baum, Richard P., Chiti, Arturo, and Krause, Bernd J.

Published
2010
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79. Multimodal Imaging Techniques to Evaluate the Anticancer Effect of Cold Atmospheric Pressure Plasma

Author

Kordt, Marcel, primary, Trautmann, Isabell, additional, Schlie, Christin, additional, Lindner, Tobias, additional, Stenzel, Jan, additional, Schildt, Anna, additional, Boeckmann, Lars, additional, Bekeschus, Sander, additional, Kurth, Jens, additional, Krause, Bernd J., additional, Vollmar, Brigitte, additional, and Grambow, Eberhard, additional

Published
2021
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83. Neuroprotective Effects of the FGF21 Analogue LY2405319

Author

Rühlmann, Claire, primary, Dannehl, David, additional, Brodtrück, Marcus, additional, Adams, Andrew C., additional, Stenzel, Jan, additional, Lindner, Tobias, additional, Krause, Bernd J., additional, Vollmar, Brigitte, additional, and Kuhla, Angela, additional

Published
2021
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84. PSMA-Radioligandentherapie könnte Nuklearmedizin vor infrastrukturelle Herausforderungen stellen: Ergebnisse einer Basiskalkulation zur Kapazitätsplanung nuklearmedizinischer Betten im deutschen Krankenhaussektor

Author

Zippel, Claus, additional, Giesel, Frederik L., additional, Kratochwil, Clemens, additional, Eiber, Matthias, additional, Rahbar, Kambiz, additional, Albers, Peter, additional, Maurer, Tobias, additional, Krause, Bernd J., additional, and Bohnet-Joschko, Sabine, additional

Published
2021
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86. Principles and Practice of PET/CT Part 2

Author

Decristoforo, Clemens, additional, Tarullo, Gianluca, additional, Grugni, Stefano, additional, Elsinga, Philip H., additional, Giurgola, Francesca, additional, Vaccaro, Ilaria, additional, Bomanji, Jamshed B., additional, Papathanasiou, Nikolaos D., additional, Oyen, Wim J.G., additional, Chiti, Arturo, additional, Bozkurt, Murat Fani, additional, Giammarile, Francesco, additional, Houzard, Claire, additional, Prompers, Leonne, additional, Beijer, Emiel, additional, Urbach, Christian, additional, Halders, Servé, additional, Mottaghy, Felix Manuel, additional, Schwarzenboeck, Sarah, additional, Souvatzoglou, Michael, additional, Krause, Bernd J., additional, Delgado-Bolton, Roberto C., additional, Carreras Delgado, José L., additional, Kunikowska, Jolanta, additional, Królicki, Leszek, additional, Ambrosini, Valentina, additional, Fanti, Stefano, additional, Hanin, François-Xavier, additional, Jamar, François, additional, Gaemperli, Oliver, additional, Kaufmann, Philipp A., additional, Darcourt, Jacques, additional, Nobili, Flavio, additional, Pagani, Marco, additional, Booij, Jan, additional, Tatsch, Klaus, additional, Poepperl, Gabriele, additional, Semah, Franck, additional, and Petyt, Gregory, additional

Published
2011
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88. Early Post-ischemic Brain Glucose Metabolism Is Dependent on Function of TLR2: a Study Using [18F]F-FDG PET-CT in a Mouse Model of Cardiac Arrest and Cardiopulmonary Resuscitation.

Author

Bajorat, Rika, Kurth, Jens, Stenzel, Jan, Vollmar, Brigitte, Krause, Bernd J., Reuter, Daniel A., Schuerholz, Tobias, and Bergt, Stefan

Abstract

Purpose: The mammalian brain glucose metabolism is tightly and sensitively regulated. An ischemic brain injury caused by cardiac arrest (CA) and cardiopulmonary resuscitation (CPR) affects cerebral function and presumably also glucose metabolism. The majority of patients who survive CA suffer from cognitive deficits and physical disabilities. Toll-like receptor 2 (TLR2) plays a crucial role in inflammatory response in ischemia and reperfusion (I/R). Since deficiency of TLR2 was associated with increased survival after CA-CPR, in this study, glucose metabolism was measured using non-invasive [18F]F-FDG PET-CT imaging before and early after CA-CPR in a mouse model comparing wild-type (WT) and TLR2-deficient (TLR2−/−) mice. The investigation will evaluate whether FDG-PET could be useful as an additional methodology in assessing prognosis. Procedures: Two PET-CT scans using 2-deoxy-2-[18F]fluoro-D-glucose ([18F]F-FDG) tracer were carried out to measure dynamic glucose metabolism before and early after CPR. To achieve this, anesthetized and ventilated adult female WT and TLR2−/− mice were scanned in PET-CT. After recovery from the baseline scan, the same animals underwent 10-min KCL-induced CA followed by CPR. Approximately 90 min after CA, measurements of [18F]F-FDG uptake for 60 min were started. The [18F]F-FDG standardized uptake values (SUVs) were calculated using PMOD-Software on fused FDG-PET-CT images with the included 3D Mirrione-Mouse-Brain-Atlas. Results: The absolute SUVmean of glucose in the whole brain of WT mice was increased about 25.6% after CA-CPR. In contrast, the absolute glucose SUV in the whole brain of TLR2−/− mice was not significantly different between baseline and measurements post CA-CPR. In comparison, baseline measurements of both mouse strains show a highly significant difference with regard to the absolute glucose SUV in the whole brain. Values of TLR2−/− mice revealed a 34.6% higher glucose uptake. Conclusions: The altered mouse strains presented a different pattern in glucose uptake under normal and ischemic conditions, whereby the post-ischemic differences in glucose metabolism were associated with the function of key immune factor TLR2. There is evidence for using early FDG-PET-CT as an additional diagnostic tool after resuscitation. Further studies are needed to use PET-CT in predicting neurological outcomes. [ABSTRACT FROM AUTHOR]

Published
2022
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92. Dosimetry of 177Lu-PSMA-617 for the treatment of metastatic castration-resistant prostate cancer: A sub-study of the VISION trial.

Author

Kurth, Jens, primary, Herrmann, Ken, additional, Eiber, Matthias, additional, Rahbar, Kambiz, additional, Heuschkel, Martin, additional, Lassmann, Michael, additional, Jentzen, Walter, additional, Chicco, Daniela, additional, Messmann, Richard, additional, Sartor, A. Oliver, additional, Morris, Michael J., additional, and Krause, Bernd J., additional

Published
2020
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93. Abnormal Regional and Global Connectivity Measures in Subjective Cognitive Decline Depending on Cerebral Amyloid Status

Author

Li, Shumei, primary, Daamen, Marcel, additional, Scheef, Lukas, additional, Gaertner, Florian C., additional, Buchert, Ralph, additional, Buchmann, Martina, additional, Buerger, Katharina, additional, Catak, Cihan, additional, Dobisch, Laura, additional, Drzezga, Alexander, additional, Ertl-Wagner, Birgit, additional, Essler, Markus, additional, Fliessbach, Klaus, additional, Haynes, John Dylan, additional, Incesoy, Enise Irem, additional, Kilimann, Ingo, additional, Krause, Bernd J., additional, Lange, Catharina, additional, Laske, Christoph, additional, Priller, Josef, additional, Ramirez, Alfredo, additional, Reimold, Matthias, additional, Rominger, Axel, additional, Roy, Nina, additional, Scheffler, Klaus, additional, Schmitt, Angelika, additional, Schneider, Anja, additional, Spottke, Annika, additional, Spruth, Eike Jakob, additional, Teipel, Stefan J., additional, Tscheuschler, Maike, additional, Wagner, Michael, additional, Wolfsgruber, Steffen, additional, Düzel, Emrah, additional, Jessen, Frank, additional, Peters, Oliver, additional, and Boecker, Henning, additional

Published
2020
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97. [Dopamine Transporter SPECT with I-123 labelled FP-CIT (DaTSCANTM)]

Author

Tatsch, Klaus, Buchert, Ralph, Bartenstein, Peter, Barthel, Henryk, Boecker, Henning, Brust, Peter, Drzezga, Alexander, La Fougère, Christian, Gründer, Gerhard, Grünwald, Frank, Krause, Bernd-J., Kuwert, Torsten, Langen, Karl-Josef, Rominger, Axel Oliver, Sabri, Osama, Schreckenberger, Mathias, and Meyer, Philipp T.

Subjects
610 Medicine & health
Abstract

The aim of the S1 guideline is to assist in establishing the indication and in performing, interpreting and reporting SPECT investigations of the dopamine transporter (DAT) with DaTSCANTM. Compared to the preceding version dated from 2007 the current update considers relevant new publications, the guidelines of the European (EANM) and Society of Nuclear Medicine (SNM), and the current version of the S3 guideline of the German Society of Neurology on "Idiopathic Parkinsonsian Syndrome". In addition new technical developments are incorporated.

Published
2019
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99. Markov random field segmentation of brain MR images

Author

Held, Karsten, Kops, Elena Rota, Krause, Bernd J., Wells, William M., III, Kikinis, Ron, and Muller-Gartner, Hans-Wilhelm

Subjects
Magnetic resonance imaging -- Evaluation, Markov processes -- Usage, Simulated annealing (Mathematics) -- Usage, Iterative methods (Mathematics) -- Usage, Brain mapping -- Analysis, Business, Electronics, Electronics and electrical industries, Health care industry
Abstract

We describe a fully-automatic three-dimensional (3-D)-segmentation technique for brain magnetic resonance (MR) images. By means of Markov random fields (MRF's) the segmentation algorithm captures three features that are of special importance for MR in, ages, i.e., nonparametric distributions of tissue intensities, neighborhood correlations, and signal inhomogeneities. Detailed simulations and real MR images demonstrate the performance of the segmentation algorithm. In particular, the impact of noise, inhomogeneity, smoothing, and structure thickness are analyzed quantitatively. Even single-echo MR images are well classified into gray matter, white matter, cerebrospinal fluid, scalp-bone, and background. A simulated annealing and an iterated conditional modes implementation are presented. Index Terms - Magnetic resonance imaging, Markov random fields, segmentation.

Published
1997

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