68 results on '"Kosuke Fujimoto"'
Search Results
52. Effect of Metal Compounds on Pyrolysis Profiles of Douglas Fir
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Hayashi Shigeya, Kosuke Fujimoto, Isao Hasegawa, Kazuhiro Mae, and Yoshikage Ohmukai
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Chemical substance ,Chemistry ,General Chemical Engineering ,Inorganic chemistry ,Metal Compound ,Tar ,General Chemistry ,medicine.disease ,Decomposition ,Metal ,visual_art ,Yield (chemistry) ,visual_art.visual_art_medium ,medicine ,Biomass ,Dehydration ,Char ,Tar Reduction ,Pyrolysis - Abstract
Pyrolysis of Douglas fir with metal compounds has been carried out to examine the effect of metal compounds on the pyrolysis profiles. The profiles dramatically shifted into lower or higher temperatures by adding some metal compounds. On the other hand, the presence of metal chlorides promoted the decomposition of Douglas fir at low temperature. The metal compounds having high hydrophilicity, by which Douglas fir decomposition was shifted toward lower temperatures, caused an increase in char and a decrease in tar through promoting the cross-linking reaction at low temperature. From these results, it can be said that the control of dehydration at low temperature is an essential factor to achieve high char yield with minimizing tar formation.
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- 2008
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53. Structure-Controlled Pyrolysis of Biomass with Sodium Hydroxide for Suppression of Tar Formation
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Kazuhiro Mae, Yoshikage Ohmukai, Isao Hasegawa, Hayashi Shigeya, and Kosuke Fujimoto
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chemistry.chemical_classification ,General Chemical Engineering ,Inorganic chemistry ,General Chemistry ,medicine.disease ,Inorganic Compound ,chemistry.chemical_compound ,chemistry ,Sodium hydroxide ,Cross-Linking ,medicine ,Biomass ,Char ,Dehydration ,Cellulose ,Pyrolysis ,Inorganic compound ,Douglas fir ,Tar yield - Abstract
Pyrolysis of NaOH-loaded Douglas fir and cellulose has been carried out to determine the effect of sodium hydroxide on the pyrolysis profile. A tar yield of 0 wt% and the char yield of 32 wt% were obtained at a final pyrolysis temperature of 500°C. It was revealed that the amount of hydroxyl groups in the residue significantly decreased at 200°C and that the structure of cellulose was distorted via cross-linking at the same temperature through spectroscopic analyses and diffraction patterns. The cross-linking led to the increase in char yield at 500°C. A detailed analysis showed that char yield from cellulose at 500°C correlated linearly with the degree of cross-linking calculated from the amount of dehydration at 200°C. These results showed a possibility that the pyrolysis profile of biomass may be controlled through an appropriate pretreatment to change the structure of the intermediate.
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- 2008
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54. Engine Oil Formulation Technology to Prevent Pre-ignition in Turbocharged Direct Injection Spark Ignition Engines
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Toyoharu Kaneko, Satoshi Ogano, Tomohiro Kato, Ko Onodera, Katsuyoshi Kato, and Kosuke Fujimoto
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Ignition system ,Materials science ,Internal combustion engine ,law ,Homogeneous charge compression ignition ,Spark (mathematics) ,Ignition timing ,Engine knocking ,Automotive engineering ,Petrol engine ,law.invention ,Turbocharger - Published
- 2015
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55. Mechanism of Turbocharger Coking in Gasoline Engines
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Masayuki Tanada, Satoshi Hirano, Itsuki Miyata, and Kosuke Fujimoto
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Environmental science ,Gasoline ,Automotive engineering ,Mechanism (sociology) ,Turbocharger - Published
- 2015
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56. Minimal neonatal transfer of certolizumab pegol in a Japanese patient with rheumatoid arthritis
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Takayoshi Morita, Yoshihito Shima, Atsushi Kumanogoh, Kosuke Fujimoto, and Atsushi Ogata
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030203 arthritis & rheumatology ,Fetus ,Pregnancy ,medicine.medical_specialty ,business.industry ,Immunology ,Breast milk ,Abortion ,medicine.disease ,General Biochemistry, Genetics and Molecular Biology ,03 medical and health sciences ,0302 clinical medicine ,medicine.anatomical_structure ,Rheumatology ,Rheumatoid arthritis ,Internal medicine ,Lactation ,medicine ,Immunology and Allergy ,030211 gastroenterology & hepatology ,Methotrexate ,Certolizumab pegol ,business ,medicine.drug - Abstract
Clowse et al 1 have reported minimal to no transfer of certolizumab pegol (CZP) into breast milk, and their findings have supported the continuation of CZP treatment during breast milk feeding. Rheumatoid arthritis (RA) often develops in women of childbearing age. It is generally difficult to treat these patients with methotrexate, which is the anchor drug for RA. Therefore, biologics, such as tumour necrosis factor (TNF) inhibitors, are often considered for active RA during pregnancy. However, the biologics cross the placenta from mother to fetus and transfer into breast milk during lactation. Although a meta-analysis report indicated that anti-TNF-α therapy did not increase the risks, such as congenital malformation or abortion during pregnancy, in patients with inflammatory …
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- 2017
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57. Detecting hybrid and electric vehicles using a smartphone
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Tohru Asami, Yoshihiro Kawahara, Kosuke Fujimoto, and Masaru Takagi
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ALARM ,Computer science ,Feature vector ,Ambient noise level ,Real-time computing ,Pedestrian ,Simulation - Abstract
Pedestrians have difficulty noticing hybrid vehicles (HVs) and electrical vehicles (EVs) quietly approaching from behind. We propose a vehicle detection scheme using a smartphone carried by a pedestrian. A notification of a vehicle approaching can be delivered to wearable devices such as Google Glass. We exploit the high-frequency switching noise generated by the motor unit in HVs and EVs. Although people are less sensitive to these high-frequency ranges, these sounds are prominent even on a busy street, and it is possible for a smartphone to detect these signals. The ambient sound captured at 48 kHz is converted to a feature vector in the frequency domain. A J48 classifier implemented on a smartphone can determine whether an EV or HV is approaching. We have collected a large amount of vehicle data at various locations. The false-positive and false-negative rates of our detection scheme are 1.2% and 4.95%, respectively. The first alarm was detected as early as 11.6 s before the vehicle approached the observer. The scheme can also determine the vehicle speed and vehicle type.
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- 2014
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58. Theoretical design of carrier injection rate and recombination rate in tunnel injection quantum well lasers
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Yasutaka Higa, Tomoyuki Miyamoto, Hiroshi Nakajima, Fumio Koyama, and Kosuke Fujimoto
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business.industry ,Chemistry ,Injection rate ,Condensed Matter Physics ,Laser ,law.invention ,Semiconductor laser theory ,law ,Picosecond ,Optoelectronics ,Spontaneous emission ,business ,Tunnel injection ,Ground state ,Quantum well - Abstract
Carrier injection rate in tunnel injection quantum well structures used in semiconductor lasers was investigated through theoretical analysis. Carrier capture time from 3D-state to 2D-state in a conventional quantum well was several ten picoseconds and it is almost uncontrollable characteristics. The tunnel injection structure can be designed to control the carrier injection rate. The carrier transition time from carrier reservoir-region of the tunnel injection structure to the active well was a few picoseconds when the structure was designed for high speed transition. As results, carrier injection to ground state of the active well takes less than 10 picoseconds. The change of the radiative recombination rate in the active well also defines the optimal design of the tunnel injection structure. (© 2008 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim)
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- 2008
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59. Influence of Engine Oil Properties on Soot Containing Deposit Formation in Turbocharger Compressor
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Koki Ito, Takeshi Nakajima, Kosuke Fujimoto, Yosuke Kudo, Norihiko Sumi, and Satoshi Hirano
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Petroleum engineering ,medicine ,Environmental science ,medicine.disease_cause ,Gas compressor ,Soot ,Turbocharger - Published
- 2013
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60. Investigation of Engine Oil Effect on Abnormal Combustion in Turbocharged Direct Injection - Spark Ignition Engines (Part 2)
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Katsuyoshi Kato, Satoshi Hirano, Kosuke Fujimoto, and Minoru Yamashita
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Ignition system ,Internal combustion engine ,law ,Homogeneous charge compression ignition ,Compression ratio ,Environmental science ,Ignition timing ,Engine knocking ,Automotive engineering ,Turbocharger ,Petrol engine ,law.invention - Published
- 2013
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61. Gut carbohydrate inhibits GIP secretion via a microbiota/SCFA/FFAR3 pathway.
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Eun-Young Lee, Xilin Zhang, Junki Miyamoto, Ikuo Kimura, Tomoaki Taknaka, Kenichi Furusawa, Takahito Jomori, Kosuke Fujimoto, Satoshi Uematsu, and Takashi Miki
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GUT microbiome ,CARBOHYDRATES ,INCRETINS ,POLYPEPTIDES ,GLUCOSIDASE inhibitors - Abstract
Mechanisms of carbohydrate-induced secretion of the two incretins namely glucagon-like peptide 1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) are considered to be mostly similar. However, we found that mice exhibit opposite secretory responses in response to co-administration of maltose plus an α-glucosidase inhibitor miglitol (maltose/miglitol), stimulatory for GLP-1, as reported previously, but inhibitory for GIP. Gut microbiota was shown to be involved in maltose/miglitol-induced GIP suppression, as the suppression was attenuated in antibiotics (Abs)-treated mice and abolished in germ-free mice. In addition, maltose/miglitol administration increased plasma levels of short-chain fatty acids (SCFAs), carbohydrate-derived metabolites, in the portal vein. GIP suppression by maltose/miglitol was not observed in mice lacking a SCFA receptor Ffar3, but it was normally seen in Ffar2-deficient mice. Similar to maltose/miglitol administration, co-administration of glucose plus a sodium glucose transporter inhibitor phloridzin (glucose/phloridzin) induced GIP suppression, which was again cancelled by Abs treatment. In conclusion, oral administration of carbohydrates with α-glucosidase inhibitors suppresses GIP secretion through a microbiota/SCFA/FFAR3 pathway. [ABSTRACT FROM AUTHOR]
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- 2018
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62. Development of ILSAC GF-5 0W-20 Fuel Economy Gasoline Engine Oil
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Toyoharu Kaneko, Kosuke Fujimoto, Ko Onodera, Yusuke Ito, Shuzo Nemoto, Satoshi Hirano, and Minoru Yamashita
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Waste management ,Environmental science ,Petrol engine - Published
- 2012
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63. Constructing Continuous-Time Chaos-Generating Templates Using Polynomial Approximation
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Kosuke Fujimoto, Shinji Okamoto, Hidetaka Ito, and Akira Kumamoto
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Physics ,Pure mathematics ,Reciprocal polynomial ,Polynomial ,Matrix (mathematics) ,Dynamical systems theory ,Attractor ,Invariant measure ,Dynamical system ,Matrix polynomial - Abstract
Aiming at developing a methodology for constructing continuous-time chaotic dynamical systems as flexible pattern generators, this paper discusses a strategy for binding desired unstable periodic orbits into a chaotic attractor. The strategy is comprised of the following two stages: constructing an interim “chaos-generating template”, and deforming the template according to the specifically desired orbits. INTRODUCTION Chaos is a fascinating phenomenon arising from nonlinearities in dynamical systems, and investigations on its applications to intelligent and flexible systems have appeared in many fields. An important aspect of chaos is that chaotic attractors embed or “host” an infinite number of unstable periodic orbits (UPO’s) bifurcated from prechaotic states (Ott, 2002). Among them, some distinctive orbits can be used for characterization or control purposes. For example, a variety of chaos control methods (Ott et al., 1990; Pyragas, 1992; Zhang et al., 2009) can stabilize UPO’s embedded in chaotic attractors, enlarging the operation range and/or enhancing the functionality of the system. In more recent years, the synthesis of chaos from various approaches (Chen and Ueta, 2002; Zelinka et al., 2008; Munoz-Pacheco and Tlelo-Cuautle, 2009) has been an active direction of research along the line of exploiting chaos. Primary concerns of these efforts include statistical and topological characteristics (e.g., invariant measure, Lyapunov spectrum, novel scrolling behaviors) that would be important in designing chaos-based information processing and communication applications. While the present study share some common motivation with the above-mentioned studies, we have put more focus on the geometrical shape and dynamical properties of UPO’s themselves from the viewpoint of the adaptive generation of periodic behaviors. Here our intention lies in extending the functionality of (stable) periodic pattern generators based on function approximation of vector fields, e.g., polynomial approximation (Okada and Nakamura, 2002) and neural network learning (Kuroe and Miura, 2006). In this paper, we consider continuous-time chaotic attractors as a container of UPO’s (patterns) where they can be stabilized, entrained, or targeted by external inputs into the dynamical system. In what follows, we propose a design strategy for binding desired UPO’s into a chaotic attractor governed by a polynomial vector field. The strategy is comprised of the following two stages: constructing an interim “chaos-generating template”, and deforming the template according to the specifically desired orbits. POLYNOMIAL VECTOR FIELDS We consider polynomial dynamical systems of the form ẋ = f(x)(x ∈ R ) where the vector field f(x) is represented as f(x) = [f1(x) · · · fN (x)] T = Φ(a(p1p2···pN ))θ(x), (1) θ(x) = [x1 · · · x ` N x `−1 1 x2 · · · 1] T . (2) Here, ` denotes the maximum degree of the polynomials, and the matrix Φ is comprised of the coefficients a(p1p2···pN ) of the polynomials. For example, with 3rdorder polynomials, the first element of a two-dimensional vector field is represented as f1(x) = a1(30)x 3 1 + a1(21)x 2 1x2 + a1(12)x1x 2 2 + a1(03)x 3 2 + a1(20)x 2 1 + a1(11)x1x2 + a1(02)x 2 2 + a1(10)x1 + a1(01)x2 + a1(00).(3) In our design process of the dynamical system, the coefficients are obtained by least-square fitting. To this end, we set up target vectors f(ηi) (i = 1, 2, · · · , L) at design points ηi on and in the vicinity of the target orbits, and construct matrices F = [f(η1) f(η2) · · · f(ηL)], (4) Θ = [θ(η1) θ(η2) · · · θ(ηL)]. (5) With these matrices, the least-square solution for Φ is given by Φ(a(p1 p2 ··· pN )) = FΘ # (6) where Θ is the Moore-Penrose pseudo inverse of Θ. Proceedings 24th European Conference on Modelling and Simulation ©ECMS Andrzej Bargiela, Sayed Azam Ali David Crowley, Eugene J.H. Kerckhoffs (Editors) ISBN: 978-0-9564944-0-5 / ISBN: 978-0-9564944-1-2 (CD)
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- 2010
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64. Theoretical analysis of high speed semiconductor optical amplifier using tunneling injection structure
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Yasutaka Higa, Tomoyuki Miyamoto, Hiroshi Nakajima, Kosuke Fujimoto, and Fumio Koyama
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Optical amplifier ,Materials science ,business.industry ,Optoelectronics ,Carrier recovery ,business ,Tunnel injection ,behavioral disciplines and activities ,Quantum tunnelling - Abstract
We propose a SOA with a tunnel injection structure and analyze the operation properties. High-speed carrier recovery was suggested in the tunnel-injection SOA. The results indicate tunnel-injection SOAs have a potential of high-speed operation.
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- 2008
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65. Regulation of humoral and cellular gut immunity by lamina propria dendritic cells expressing Toll-like receptor 5
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Masafumi Yamamoto, Myoung Ho Jang, Ken Ishii, Satoshi Uematsu, Shintaro Sato, Yun-Jae Jung, Bo-Gie Yang, Mika Nishiyama, Yoshifumi Yokota, Masayuki Miyasaka, Hiroshi Kiyono, Kosuke Fujimoto, Shizuo Akira, and Tohru Tsujimura
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T-Lymphocytes ,Immunology ,Enzyme-Linked Immunosorbent Assay ,Tretinoin ,Biology ,Lymphocyte Activation ,Interleukin 21 ,Mice ,medicine ,Immunology and Allergy ,Cytotoxic T cell ,Animals ,Immunity, Mucosal ,Interleukin 4 ,Cells, Cultured ,Interleukin 3 ,Lamina propria ,B-Lymphocytes ,Immunity, Cellular ,CD40 ,Mucous Membrane ,Follicular dendritic cells ,Reverse Transcriptase Polymerase Chain Reaction ,Dendritic Cells ,Flow Cytometry ,Immunohistochemistry ,Gut-specific homing ,Cell biology ,Immunoglobulin A ,Toll-Like Receptor 5 ,medicine.anatomical_structure ,Antibody Formation ,biology.protein ,Flagellin - Abstract
The intestinal cell types responsible for defense against pathogenic organisms remain incompletely characterized. Here we identify a subset of CD11c(hi)CD11b(hi) lamina propria dendritic cells (LPDCs) that expressed Toll-like receptor 5 (TLR5) in the small intestine. When stimulated by the TLR5 ligand flagellin, TLR5(+) LPDCs induced the differentiation of naive B cells into immunoglobulin A-producing plasma cells by a mechanism independent of gut-associated lymphoid tissue. In addition, by a mechanism dependent on TLR5 stimulation, these LPDCs promoted the differentiation of antigen-specific interleukin 17-producing T helper cells and type 1 T helper cells. Unlike spleen DCs, the LPDCs specifically produced retinoic acid, which, in a dose-dependent way, supported the generation and retention of immunoglobulin A-producing cells in the lamina propria and positively regulated the differentiation interleukin 17-producing T helper cells. Our findings demonstrate unique properties of LPDCs and the importance of TLR5 for adaptive immunity in the intestine.
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- 2008
66. Fungal ITS1 Deep-Sequencing Strategies to Reconstruct the Composition of a 26-Species Community and Evaluation of the Gut Mycobiota of Healthy Japanese Individuals.
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Daisuke Motooka, Kosuke Fujimoto, Reiko Tanaka, Takashi Yaguchi, Kazuyoshi Gotoh, Yuichi Maeda, Yoki Furuta, Takashi Kurakawa, Naohisa Goto, Teruo Yasunaga, Masashi Narazaki, Atsushi Kumanogoh, Toshihiro Horii, Tetsuya Iida, Kiyoshi Takeda, and Shota Nakamura
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HUMAN microbiota ,CANDIDA albicans - Abstract
The study of mycobiota remains relatively unexplored due to the lack of sufficient available reference strains and databases compared to those of bacterial microbiome studies. Deep sequencing of Internal Transcribed Spacer (ITS) regions is the de facto standard for fungal diversity analysis. However, results are often biased because of the wide variety of sequence lengths in the ITS regions and the complexity of high-throughput sequencing (HTS) technologies. In this study, a curated ITS database, ntF-ITS1, was constructed. This database can be utilized for the taxonomic assignment of fungal community members. We evaluated the efficacy of strategies for mycobiome analysis by using this database and characterizing a mock fungal community consisting of 26 species representing 15 genera using ITS1 sequencing with three HTS platforms: Illumina MiSeq (MiSeq), Ion Torrent Personal Genome Machine (IonPGM), and Pacific Biosciences (PacBio). Our evaluation demonstrated that PacBio's circular consensus sequencing with greater than 8 full-passes most accurately reconstructed the composition of the mock community. Using this strategy for deepsequencing analysis of the gut mycobiota in healthy Japanese individuals revealed two major mycobiota types: a single-species type composed of Candida albicans or Saccharomyces cerevisiae and a multi-species type. In this study, we proposed the best possible processing strategies for the three sequencing platforms, of which, the PacBio platform allowed for the most accurate estimation of the fungal community. The database and methodology described here provide critical tools for the emerging field of mycobiome studies. [ABSTRACT FROM AUTHOR]
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- 2017
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67. Vibration wave driving apparatus and method of setting shape of support member supporting elastic member forming vibration member of vibration wave driving apparatus
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Mitsuo Nishimura, Kosuke Fujimoto, Shinji Yamamoto, and Mori Takao
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Materials science ,Acoustics and Ultrasonics ,Frequency band ,Acoustics ,Mode (statistics) ,Stiffness ,Natural frequency ,Vibration ,Arts and Humanities (miscellaneous) ,Active vibration control ,Physics::Atomic and Molecular Clusters ,medicine ,Energy transformation ,Physics::Chemical Physics ,medicine.symptom - Abstract
The invention relates to a vibration wave driving apparatus which comprises a vibration member in which an electro-mechanical energy conversion element is fixed to the elastic member, and a contact member pressed against a sliding part provided in the vibration member, so as to be kept in contact therewith, and which is configured to supply alternating signals in a predetermined driving frequency band to the electro-mechanical energy conversion element, thereby generating a predetermined natural vibration mode in the elastic member to drive the contact member. In the apparatus, the natural vibration mode is generated in the elastic member, a natural frequency of another vibration mode different from the natural vibration mode is detected, and a stiffness of the support member is altered if the natural frequency of the other vibration mode detected is included in the driving frequency band.
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- 2008
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68. Minimal neonatal transfer of certolizumab pegol in a Japanese patient with rheumatoid arthritis.
- Author
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Takayoshi Morita, Kosuke Fujimoto, Yoshihito Shima, Atsushi Ogata, Atsushi Kumanogoh, Morita, Takayoshi, Fujimoto, Kosuke, Shima, Yoshihito, Ogata, Atsushi, and Kumanogoh, Atsushi
- Published
- 2018
- Full Text
- View/download PDF
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