51. Magnetic resonance microscopy of chemically fixed human embryos at high spatial resolution
- Author
-
Kohei Shiota, Yosuke Otake, Katsumi Kose, Shinya Handa, Shigehito Yamada, and Chigako Uwabe
- Subjects
Microscope ,Anatomical structures ,Datasets as Topic ,Gestational Age ,Superconducting magnet ,Signal-To-Noise Ratio ,Signal ,law.invention ,Nuclear magnetic resonance ,Imaging, Three-Dimensional ,law ,medicine ,High spatial resolution ,Image Processing, Computer-Assisted ,Humans ,Radiology, Nuclear Medicine and imaging ,Microscopy ,medicine.diagnostic_test ,Anatomy, Cross-Sectional ,business.industry ,Magnetic resonance microscopy ,Dynamic range ,Magnetic resonance imaging ,Anatomy ,Embryo, Mammalian ,Magnetic Resonance Imaging ,business - Abstract
We acquired magnetic resonance (MR) microscopic images of chemically fixed human embryos of Carnegie stages 16 to 22 with a large image matrix (256 × 256 × 512) using an MR microscope that we developed with a 9.4-tesla vertical wide-bore superconducting magnet and a dual-channel receiver system to extend the dynamic range of the MR signal. The images showed clear anatomical structures at spatial resolutions of (40 µm)(3) to (60 µm)(3). We concluded that the experimental technique we developed will aid construction of the next anatomical database of the collection of chemically fixed human embryos.
- Published
- 2015