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51. MPSK-MIMO FMCW Radar-Based Indoor Multipath Recognition

Author

Park, Jeong-Ki, Park, Jae-Hyun, Kang, Dong-Kook, Jeong, Jun-Ho, and Kim, Kyung-Tae

Abstract

We propose a scheme for indoor multipath recognition to identify ghost targets using multiple-input multiple-output frequency-modulated continuous-wave (MIMO FMCW) radar. For ensuring the orthogonality of the transmitted signals, the M-ary phase-shift keying (MPSK) method was exploited. According to an in-depth analysis of the phase information contained in the received signals using MPSK-MIMO FMCW radar, direction-of-arrival (DoA) and direction-of-departure (DoD) information was investigated to identify the multipath. To achieve this, clutter suppression, spatial filtering, and high-resolution DoA/DoD estimation were performed. Simulation and experimental results obtained using a commercial MIMO FMCW radar system indicated that the proposed method can discriminate direct paths from persons and multipaths.

Published
2024
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53. Pharmacokinetic Interactions Between the Fixed-Dose Combination of Ezetimibe/Rosuvastatin 10/20 Mg and the Fixed-Dose Combination of Telmisartan/Amlodipine 80/5 Mg in Healthy Subjects

Author

Ryu,Hyunwook, Kim,Hyun Chul, Jeon,Inseung, Jang,In-Jin, Cho,Joo-Youn, Kim,Kyung Tae, Oh,Jaeseong, Ryu,Hyunwook, Kim,Hyun Chul, Jeon,Inseung, Jang,In-Jin, Cho,Joo-Youn, Kim,Kyung Tae, and Oh,Jaeseong

Abstract

Hyunwook Ryu,1 Hyun Chul Kim,1 Inseung Jeon,1 In-Jin Jang,1 Joo-Youn Cho,1,2 Kyung Tae Kim,3 Jaeseong Oh1,4,5 1Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul, Republic of Korea; 2Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, Republic of Korea; 3Addpharma, Inc., Yongin-si, Gyeonggi-do, Republic of Korea; 4Department of Pharmacology, Jeju National University College of Medicine, Jeju, Republic of Korea; 5Clinical Research Institute, Jeju National University Hospital, Jeju, Republic of KoreaCorrespondence: Jaeseong Oh, Department of Pharmacology, Jeju National University College of Medicine, Jeju, Republic of Korea, Email jaeseong5@jejunu.ac.krBackground: Management of hypertension and hyperlipidemia, which are common comorbid risk factors for cardiovascular diseases, require multiple medications. The development of a fixed-dose combination (FDC) containing ezetimibe, rosuvastatin, telmisartan, and amlodipine aims to enhance patient adherence and persistence, but the potential interactions among the four medications have not been studied. This study aimed to evaluate the pharmacokinetic (PK) interactions between the FDC of ezetimibe/rosuvastatin 10/20 mg (ER) and the FDC of telmisartan/amlodipine 80/5 mg (TA).Methods: An open-label, single-sequence, three-period, three-treatment crossover study was conducted in healthy male subjects. All subjects received ER for 7 days, TA for 9 days and ER combined with TA for 7 days during each treatment period. For PK analysis of total/free ezetimibe, rosuvastatin, telmisartan, and amlodipine, serial blood samples were collected for 24 hours at steady state. Safety profiles were assessed throughout the study.Results: Thirty-eight subjects were enrolled, and 34 subjects completed the study. The systemic exposure to each active ingredient after coadministration of the two FDCs was similar to that after each FDC alone. Th

Published
2024

55. The utility of intraoperative ultrasonography for spinal cord surgery.

Author

Park, Hangeul, Kim, Jun-Hoe, Lee, Chang-Hyun, Kim, Sum, Kim, Young-Rak, Kim, Kyung-Tae, Kim, Ji-hoon, Rhee, John M., Jo, Woo-Young, Oh, Hyongmin, Park, Hee-Pyoung, and Kim, Chi Heon

Subjects
SPINAL cord surgery, OPERATIVE ultrasonography, DURA mater, BLOOD vessels
Abstract

Objectives: Intraoperative ultrasonography (IOUS) offers the advantage of providing real-time imaging features, yet it is not generally used. This study aims to discuss the benefits of utilizing IOUS in spinal cord surgery and review related literature. Materials and methods: Patients who underwent spinal cord surgery utilizing IOUS at a single institution were retrospectively collected and analyzed to evaluate the benefits derived from the use of IOUS. Results: A total of 43 consecutive patients were analyzed. Schwannoma was the most common tumor (35%), followed by cavernous angioma (23%) and ependymoma (16%). IOUS confirmed tumor extent and location before dura opening in 42 patients (97.7%). It was particularly helpful for myelotomy in deep-seated intramedullary lesions to minimize neural injury in 13 patients (31.0% of 42 patients). IOUS also detected residual or hidden lesions in 3 patients (7.0%) and verified the absence of hematoma post-tumor removal in 23 patients (53.5%). In 3 patients (7.0%), confirming no intradural lesions after removing extradural tumors avoided additional dural incisions. IOUS identified surrounding blood vessels and detected dural defects in one patient (2.3%) respectively. Conclusions: The IOUS can be a valuable tool for spinal cord surgery in identifying the exact location of the pathologic lesions, confirming the completeness of surgery, and minimizing the risk of neural and vascular injury in a real-time fashion. [ABSTRACT FROM AUTHOR]

Published
2024
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73. Clinical Factors, Treatment Selection, and Outcomes in Postcataract Fungal Endophthalmitis from Contaminated Viscoelastics

Author

Kim, Jae Hui, primary, Choi, Mihyun, additional, Kim, Seong-Woo, additional, Park, Kyu Hyung, additional, Nam, Dong Heun, additional, Lee, Dae Yeong, additional, Park, Young-Hoon, additional, Park, Young-Gun, additional, Kim, Mirinae, additional, Lee, Mee Yon, additional, Choi, Soon-Il, additional, Kim, Min, additional, Lee, Junwon, additional, Moon, Sang Woong, additional, Chung, Hyewon, additional, Lee, Young Hoon, additional, Lee, Min Woo, additional, Shin, Jae Pil, additional, Park, Dong Ho, additional, Park, Han Sang, additional, Kang, Yong Koo, additional, Chung, In Young, additional, Yoo, Woong-Sun, additional, Cho, Yong-Wun, additional, Kim, Yu Cheol, additional, Kang, Kyung Tae, additional, Jang, Ji Hye, additional, Choi, Kwang-Eon, additional, Nam, Ki Tae, additional, Kim, Young Ho, additional, Ahn, So Min, additional, Lee, Sang Joon, additional, Lim, Jae Wan, additional, Ku, Hee Chan, additional, Yoo, Su Jin, additional, Choi, Moon Jung, additional, Lew, Young Ju, additional, Kim, Jae Hui, additional, Kim, Joo Yeon, additional, Hwang, Jae Hyung, additional, Lee, Seung Woo, additional, Bae, Kunho, additional, Jeong, Woo Jin, additional, Kwon, Yoon Hyung, additional, An, Seoung Hyun, additional, Ahn, Jeeyun, additional, Shin, Joo Young, additional, Byon, Ik Soo, additional, Park, Sung Who, additional, Kang, Se Woong, additional, Ham, Don-Il, additional, Kim, Sang Jin, additional, Park, Un Chul, additional, Oh, Baek Lok, additional, Kim, June-Gone, additional, Lee, Joo Yong, additional, Lee, Jun Yeop, additional, Kim, Yoon Jeon, additional, Chae, Ju Byung, additional, Kim, Dong Yoon, additional, Lee, Christopher Seungkyu, additional, Cho, Kwan Hyuk, additional, Kim, Min Seok, additional, Kim, Seong Wook, additional, Lee, Jung Pil, additional, Kim, Hoon Dong, additional, Cho, In Hwan, additional, Song, Ji Hun, additional, Lee, Ki Hwang, additional, Kwon, Han Jo, additional, Lee, Seung Min, additional, Sagong, Min, additional, Lee, Tae Gon, additional, Han, Jung Il, additional, Chang, Young Suk, additional, Min, Jung Kee, additional, Yang, Yun Sik, additional, Kim, Soo Han, additional, Chin, Hee Seung, additional, Ji, Yong Sok, additional, Lee, Jong Young, additional, Kim, Seong Taeck, additional, Shin, Min Ho, additional, Kim, Jee Taek, additional, Han, Yong Seop, additional, Lee, Woo Hyuk, additional, Jo, Young Joon, additional, Kim, Jung Yeul, additional, Kim, Kyung Tae, additional, Seo, Eoi Jong, additional, Lim, Sun Taek, additional, Lee, Jun Sung, additional, Kim, Chang Ryong, additional, Duck-Jin Hwang, Daniel, additional, Kim, Ha Kyoung, additional, Ma, Dae Joong, additional, Hong, In Hwan, additional, Cho, Bum Joo, additional, Shin, Yong Un, additional, Cho, Heeyoon, additional, and Ahn, Seong Joon, additional

Published
2023
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98. Clinical Factors, Treatment Selection, and Outcomes in Postcataract Fungal Endophthalmitis from Contaminated Viscoelastics

Author

Kim, Jae Hui, Choi, Mihyun, Kim, Seong-Woo, Park, Kyu Hyung, Nam, Dong Heun, Lee, Dae Yeong, Park, Young-Hoon, Park, Young-Gun, Kim, Mirinae, Lee, Mee Yon, Choi, Soon-Il, Kim, Min, Lee, Junwon, Moon, Sang Woong, Chung, Hyewon, Lee, Young Hoon, Lee, Min Woo, Shin, Jae Pil, Park, Dong Ho, Park, Han Sang, Kang, Yong Koo, Chung, In Young, Yoo, Woong-Sun, Cho, Yong-Wun, Kim, Yu Cheol, Kang, Kyung Tae, Jang, Ji Hye, Kim, Seong-Woo, Choi, Kwang-Eon, Choi, Mihyun, Nam, Ki Tae, Kim, Young Ho, Ahn, So Min, Lee, Sang Joon, Lim, Jae Wan, Ku, Hee Chan, Yoo, Su Jin, Choi, Moon Jung, Lew, Young Ju, Kim, Jae Hui, Kim, Joo Yeon, Hwang, Jae Hyung, Lee, Seung Woo, Bae, Kunho, Jeong, Woo Jin, Kwon, Yoon Hyung, An, Seoung Hyun, Ahn, Jeeyun, Shin, Joo Young, Byon, Ik Soo, Park, Sung Who, Park, Kyu Hyung, Kang, Se Woong, Ham, Don-Il, Kim, Sang Jin, Park, Un Chul, Oh, Baek Lok, Kim, June-Gone, Lee, Joo Yong, Lee, Jun Yeop, Kim, Yoon Jeon, Chae, Ju Byung, Kim, Dong Yoon, Lee, Christopher Seungkyu, Cho, Kwan Hyuk, Kim, Min Seok, Kim, Seong Wook, Lee, Jung Pil, Kim, Hoon Dong, Cho, In Hwan, Song, Ji Hun, Lee, Ki Hwang, Kwon, Han Jo, Lee, Seung Min, Sagong, Min, Lee, Tae Gon, Han, Jung Il, Chang, Young Suk, Min, Jung Kee, Yang, Yun Sik, Kim, Soo Han, Chin, Hee Seung, Ji, Yong Sok, Lee, Jong Young, Kim, Seong Taeck, Shin, Min Ho, Kim, Jee Taek, Han, Yong Seop, Lee, Woo Hyuk, Jo, Young Joon, Kim, Jung Yeul, Kim, Kyung Tae, Seo, Eoi Jong, Lim, Sun Taek, Lee, Jun Sung, Kim, Chang Ryong, Duck-Jin Hwang, Daniel, Kim, Ha Kyoung, Ma, Dae Joong, Hong, In Hwan, Cho, Bum Joo, Shin, Yong Un, Cho, Heeyoon, and Ahn, Seong Joon

Abstract

To investigate the factors associated with treatment outcomes of postcataract surgery fungal endophthalmitis outbreaks related to contaminated viscoelastics.

Published
2024
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