95 results on '"Kazuki Nishimura"'
Search Results
52. Characterization of amorphous aluminium oxide thin films synthesized by mist-CVD
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Zenji Yatabe, Koshi Nishiyama, Yusui Nakamura, Takaaki Tsuda, and Kazuki Nishimura
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chemistry.chemical_compound ,Atomic layer deposition ,Materials science ,chemistry ,Chemical engineering ,Vacuum deposition ,Aluminium oxide ,Deposition (phase transition) ,Metalorganic vapour phase epitaxy ,Chemical vapor deposition ,Thin film ,Amorphous solid - Abstract
With its wide-bandgap (~7 eV), high breakdown field (~ 10 MV/cm) and high dielectric constant (~9) amorphous aluminum oxide (Al 2 O 3 ) film is an attractive material for applications as gate insulator and/or surface passivation layers for electrical devices. Using several vacuum deposition techniques, such as sputtering, metal organic chemical vapor deposition (MOCVD) and atomic layer deposition (ALD), high-quality Al 2 O 3 thin films have been reportedly obtained. One alternative approach to obtain high-quality Al 2 O 3 thin films is the mist chemical vapor deposition (mist-CVD), which can deposit various metal oxide thin films from relative non-toxic and nonpyrophoric aqueous solution, resulting in relatively simple and low-cost. In this study, we report on the deposition of Al 2 O 3 thin films by atmospheric pressure solution-processed mist chemical vapor deposition (mist-CVD) technique at 400 °C and subsequent investigation of the chemical properties, crystallinity, bandgap, mass density and refractive index of the deposited films. We confirmed that the obtained values are comparable to those reported for high-quality amorphous Al 2 O 3 thin films deposited by ALD.
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- 2019
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53. Synthesis and characterization of AlTiO films by mist-CVD
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Yusui Nakamura, Kazuki Nishimura, Zenji Yatabe, Takaaki Tsuda, and Koshi Nishiyama
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Materials science ,Band gap ,Alloy ,Analytical chemistry ,chemistry.chemical_element ,Dielectric ,Chemical vapor deposition ,engineering.material ,Titanium oxide ,X-ray photoelectron spectroscopy ,chemistry ,Aluminium ,engineering ,Spectroscopy - Abstract
High-k dielectric aluminum titanium oxide (AlTiO, an alloy of Al 2 O 3 and TiO 2 ) films were obtained by mist chemical vapor deposition (mist-CVD), utilizing Al 2 O 3 and TiO 2 precursors. By X-ray fluorescence (XRF) investigations, atomic composition ratios of Al and Ti ratios in the Al x Ti y O films were verified. X-ray diffraction (XRD) revealed that the Al x Ti y O films deposited at 400 °C has amorphous-phase structure. It was shown that the refractive index and mass density of the Al x Ti y O films increases with increase in the Ti composition. Bandgap of the Al x Ti y O films was also estimated from X-ray photoelectron spectroscopy (XPS) and ultraviolet-visible spectroscopy. It was found that the bandgap of the Al x Ti y O films decrease with increase in the Ti composition. Moreover, the obtained refractive index, mass density and bandgap of Al 2 O 3 and TiO 2 films are all comparable to those reported for high-quality Al 2 O 3 and TiO 2 films deposited by ALD, thereby demonstrating the efficacy of using mist-CVD in synthesizing films having almost the same properties as those prepared by the more mature ALD.
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- 2019
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54. Study on User Acceptability for Nishiharima MaaS Demonstration Experiment
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Jyunji Nishida, Kazuki Nishimura, and Toshiyuki Nakamura
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User acceptability ,Computer science ,Human–computer interaction - Published
- 2021
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55. Stress Graphitization Behavior of c/c Composites Fabricated from Milled Short Pitch-Based Carbon Fibers and their Electrical Properties.
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Toshihira Irisawa, Kazuki Nishimura, Tetsuya Yamamoto, Yasuhiro Tanabe, and Norio Iwashita
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This study focuses on the possibility of applying recycled carbon fiber (CF) as a high electric conductivity material for use in CF-reinforced carbon composites, i.e., the so-called c/c composites, in the future. For this application, discontinuous CF- reinforced furan resin films were molded, and discontinuous CFreinforced carbon (D-c/c) films were fabricated through carbonization and graphitization, respectively (D-c/c-C: after carbonization at 1500 °C, D-c/c-G: after graphitization at 3000 °C. The apparent density of the matrix in Dc/c-C increased owing to stress graphitization, leading to this densification of the matrix after the graphitization process. Stress graphitization was proved by varying the shrinkage of the matrix with the amount of hardener added. The electrical conductivity of D-c/c-c-G, where graphitization progressed the most, reached 1.80 × 105 S/m. We revealed the possibility of using D-c/c-G as a high-conductivity material for future applications. [ABSTRACT FROM AUTHOR]
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- 2021
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56. The relationship between health-related quality of life measures, daily rhythm of oral temperature and lifestyle in young men
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Sho Onodera, Noboru Takamoto, Yuka Nose, Hidetaka Yamaguchi, Akira Yoshioka, Kazuki Nishimura, and Koji Nagasaki
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Health related quality of life ,Gerontology ,03 medical and health sciences ,0302 clinical medicine ,Rhythm ,business.industry ,Oral temperature ,Medicine ,Physical Therapy, Sports Therapy and Rehabilitation ,Orthopedics and Sports Medicine ,030229 sport sciences ,business ,030217 neurology & neurosurgery - Published
- 2016
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57. Effects of Low-intensity Exercise in the Morning on Afternoon Exercise Performance
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Koji Nagasaki, Akira Yoshioka, Sho Onodera, Hidetaka Yamaguchi, Kazuki Nishimura, Manabu Sakai, and Noboru Takamoto
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medicine.medical_specialty ,business.industry ,Low intensity exercise ,Exercise performance ,Physical therapy ,Medicine ,business ,Morning - Published
- 2015
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58. Synthesis and characterization of mist chemical vapor deposited aluminum titanium oxide films
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Nishiyama, Koshi, Tsuda, Takaaki, Nishimura, Kazuki, Nakamura, Yusui, Zenji, Yatabe, Koshi, Nishiyama, Takaaki, Tsuda, Kazuki, Nishimura, and Yusui, Nakamura
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010302 applied physics ,Materials science ,Physics and Astronomy (miscellaneous) ,General Engineering ,chemistry.chemical_element ,General Physics and Astronomy ,Chemical vapor deposition ,01 natural sciences ,Titanium oxide ,Atomic layer deposition ,chemistry ,Aluminium ,0103 physical sciences ,Nuclear chemistry - Abstract
Aluminium titanium oxide (Alalt;subagt;1–alt;iagt;xalt;/iagt;alt;/subagt;Tialt;/subagt;alt;iagt;alt;subagt;xalt;/subagt;alt;/iagt;alt;/subagt;Oalt;subagt;alt;iagt;yalt;/iagt;alt;/subagt;, an alloy of Alalt;subagt;2alt;/subagt;Oalt;subagt;3alt;/subagt; and TiOalt;subagt;2alt;/subagt;), an attractive high-κ dielectric material, were synthesized by mist chemical vapor deposition, utilizing Alalt;subagt;2alt;/subagt;Oalt;subagt;3alt;/subagt; and TiOalt;subagt;2alt;/subagt; precursors. X-ray diffraction investigations revealed that the Alalt;subagt;1–alt;iagt;xalt;/iagt;alt;/subagt;Tialt;subagt;alt;iagt;xalt;/iagt;alt;/subagt;Oalt;subagt;alt;iagt;yalt;/iagt;alt;/subagt; (0 alt; alt;iagt;xalt;/iagt; alt; 0.72) films deposited at 400 oC has amorphous-phase structure. It was found that the bandgap of the Alalt;subagt;1–alt;iagt;xalt;/iagt;alt;/subagt;Tialt;subagt;alt;iagt;xalt;/iagt;alt;/subagt;Oalt;subagt;alt;iagt;yalt;/iagt;alt;/subagt;, films decreases with increasing Ti composition. Moreover, the obtained refractive index, mass density and bandgap of Alalt;subagt;2alt;/subagt;Oalt;subagt;3alt;/subagt; and TiOalt;subagt;2alt;/subagt; films are all comparable to those reported for high-quality Alalt;subagt;2alt;/subagt;Oalt;subagt;3alt;/subagt; and TiOalt;subagt;2alt;/subagt; films deposited by atomic layer deposition.
- Published
- 2019
59. Suitability of modified tandem-bicycle ergometer for the improvement of physical fitness and athletic performance
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Hiroshi Kawano, Kazutoshi Seki, Hidetaka Yamaguchi, Yusuke Takagi, Keisho Katayama, Megumi Murata, Takuma Wada, Akira Yoshioka, Yuka Nose, Sho Onodera, Nozomi Matsumoto, Wooram Baik, Sotaro Hayashi, Tatsuya Saito, Futoshi Ogita, Kazuki Nishimura, and Keita Arakane
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Rating of perceived exertion ,medicine.medical_specialty ,Physiology ,business.industry ,Physical fitness ,coefficient of variations ,Oxygen uptake ,tandem-bicycle ergometer ,oxygen uptake ,Physical medicine and rehabilitation ,rating of perceived exertion ,Sports medicine ,Heart rate ,heart rate ,medicine ,Physical therapy ,QP1-981 ,Bicycle ergometer ,business ,RC1200-1245 - Abstract
In the present study, a tandem-bicycle ergometer was developed, because it is believed that such an ergometer can be used to eliminate differences in signaling between single- and tandem-exercise in cardiorespiratory responses, and is able to quantify interdependence in one load. It is necessary to verify whether cardiorespiratory responses to submaximal exercise are the same between single and tandem-bicycle ergometers. Accordingly, we compared cardiorespiratory variables during exercise in three conditions: 1) with a general bicycle single saddle using a general bicycle ergometer, 2) with a tandem bicycle front saddle using a tandem ergometer, and 3) with a tandem bicycle rear saddle using a tandem ergometer. Eleven healthy males participated in this study. The subjects exercised for 15 min at three intensities (1.5, 2.0 and 2.5 kp) in each condition. The pedaling rate was constantly kept at 60 rpm. Heart rate (HR), oxygen uptake (VO2), and the rating of perceived exertion (RPE) were measured during the last minute of each intensity. There were no significant differences in the variables HR, VO2, and RPE at each load among the three conditions. The ranges of coefficient of variation (CV) values were 3.0 - 4.8%: HR and 4.2 - 5.1%: VO2. It was reported that between-day CV for HR and VO2 during treadmill running was 1.0 - 10.7% and 1.9 - 11.6%. Given these CV values of present and previous studies, it can be seen that physiological response is stable during developed tandem-bicycle ergometer exercise. These results suggest that cardiorespiratory responses to exercise are at comparable levels between a normal bicycle ergometer and the newly developed tandem-bicycle ergometer.
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- 2015
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60. Effects of periodic hypobaric and hypoxic environment systems on the anaerobic threshold.
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Kazuki NISHIMURA, Yutaro TAMARI, and Koji NAGASAKI
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Purpose: This study aimed to determine the relationship between exercise in a periodic hypobaric hypoxic environment (PHHE) system, which we developed, and the anaerobic threshold. Methods: Fifteen healthy men were recruited, and written informed consent was obtained. The participants performed a graded cycle ergometer exercise test, with each stage lasting 90 seconds. Exercise intensity was initially set at 10 W and was increased by 10 W at succeeding stages. We established three experimental conditions: exercise in a PHHE system (periodic), at an altitude of 750 m (fixed), and at an altitude of 0 m (control). The periodic condition varied between decreased pressure at an altitude of 1,500 m for 180 seconds and increased pressure at an altitude of 0 m for 180 seconds. Heart rate, blood pressure, double product (DP), cardiac autonomic nervous system modulation, and arterial oxygen saturation were measured during each exercise stage. Results: The DP breaking point and breaking point of natural logarithm of high frequency were significantly reached at higher exercise intensity in the periodic and control conditions than in the fixed condition. Discussion: The results suggest that the efficiency of oxygen uptake through repeated exposure might enhance aerobic energy supply. In conclusion, the anaerobic threshold under PHHE was found to be enhanced compared with that at a fixed average altitude. [ABSTRACT FROM AUTHOR]
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- 2024
61. 56.4: New Deep Blue Fluorescent Materials and Their Application to High Performance OLEDs
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Yumiko Mizuki, Kazuki Nishimura, Masakazu Funahashi, Ryo Naraoka, Hiroyuki Saito, Chishio Hosokawa, Toshihiro Iwakuma, Hitoshi Kuma, Yukitoshi Jinde, Masahiro Kawamura, and Yuichiro Kawamura
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Materials science ,business.industry ,Stacking ,OLED ,Fluorescent materials ,Optoelectronics ,Color temperature ,business ,Deep blue ,Phosphorescence ,Layer (electronics) ,Fluorescence - Abstract
We developed highly efficient deep blue fluorescent materials. The bottom-emission OLED showed a CIE1931 coordinate of (0.14, 0.08) and a current efficiency of 6.5 cd/A with using a new efficiency-enhancement layer. We achieved CIEy of 0.062, a current efficiency of 7.5 cd/A and lifetime (LT95) of 2,000 hrs by depositing a new organic capping layer on a top-emission blue OLEDs, A hybrid white OLED by stacking a deep blue fluorescence and a phosphorescent red/green stacked yellow was also demonstrated which has an efficacy of 23 lm/W and color temperature of 10,000 K at 10 mA/cm2 and lifetime (LT50) of over 60,000 hrs at a luminance of 1,000 cd/m2.
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- 2011
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62. Recent transposition activity of Xenopus T2 family miniature inverted-repeat transposable elements
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Kazuki Nishimura, Tomoe Hikosaka-Katayama, Akira Kawahara, and Akira Hikosaka
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Transposable element ,Inverted repeat ,Inverted Repeat Sequences ,Xenopus ,Molecular Sequence Data ,Locus (genetics) ,Polymerase Chain Reaction ,law.invention ,Evolution, Molecular ,law ,Genetics ,Mite ,Animals ,Molecular Biology ,Western clawed frog ,Polymerase chain reaction ,DNA Primers ,Polymorphism, Genetic ,Base Sequence ,biology ,Sequence Analysis, DNA ,General Medicine ,biology.organism_classification ,DNA Transposable Elements - Abstract
To investigate the recent transposition activity of T2 family miniature inverted-repeat transposable elements (MITEs) in Xenopus tropicalis (Western clawed frog), we analyzed the intraspecific polymorphisms associated with MITE insertion in X. tropicalis for three subfamilies of the T2 family (T2-A1, T2-C, and T2-E). A high frequency of MITE-insertion polymorphisms was observed at the T2-A1 (50%) and T2-C insertion loci (60%), but none were noted at the T2-E insertion locus (0%). Analyses of the collected data indicated that members of the T2-A1 and T2-C subfamilies may be currently active in the host species. Identification of these active transpositions will help us in understanding the mechanisms underlying the long-term survival (over several tens of millions of years) of the T2-A1 and T2-C subfamilies.
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- 2011
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63. Development of Moving Finite Element Methods for Fast Crack Propagation in Functionally Graded Materials
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Toshihisa Nishioka, Kazuki Nishimura, and Takehiro Fujimoto
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Materials science ,Mechanics of Materials ,business.industry ,Mechanical Engineering ,General Materials Science ,Development (differential geometry) ,Fracture mechanics ,Structural engineering ,business ,Finite element method - Published
- 2010
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64. Effects of the Difference of Intense of Exercise of Footbath on Heart Rate, Oxygen uptake and Rectal Temperature during Arm Cranking Exercise
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Hiroshi, Amaoka, Kazuki, Nishimura, Kazutoshi, Seki, Sho, Onodera, Department of Health and Human Performance, School of Social Welfare, KIBI International University, Doctoral Program in Health Science, Graduate School of Medical Profession, Kawasaki University of Medical Welfare, and Department of Health and Sports Science, Kawasaki University of Medical Welfare
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有酸素運動 ,足浴 ,運動強度 - Published
- 2009
65. Relationship between Practicing Activity of Individual Support and Achievement of tasks in Water Exercise for The Children with Autism Spectrum Disorders
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Akira Yoshioka, Kazuki Nishimura, Wooram Baik, Kumiko Ono, Kazutoshi Seki, Terumasa Takahara, Sho Onodera, Yasuo Ishida, Mayo Komiyama, and Tomoko Fujisawa
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medicine.medical_specialty ,medicine ,Autism ,Mind-blindness ,Water exercise ,medicine.disease ,Psychology ,Psychiatry ,Clinical psychology - Published
- 2007
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66. Effects of Low-Intensity Exercise in the Morning on Physiological Responses During Unsteady Workload Exercise in the Evening
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Koji Nagasaki, Hidetaka Yamaguchi, Noboru Takamoto, Kazuki Nishimura, Sho Onodera, and Akira Yoshioka
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Adult ,Male ,medicine.medical_specialty ,Evening ,Time Factors ,chemistry.chemical_element ,Physical Therapy, Sports Therapy and Rehabilitation ,Blood Pressure ,Workload ,Oxygen ,03 medical and health sciences ,Young Adult ,0302 clinical medicine ,Oxygen Consumption ,Heart Rate ,Internal medicine ,Heart rate ,medicine ,Humans ,Orthopedics and Sports Medicine ,Exercise ,Morning ,Exercise Tolerance ,business.industry ,VO2 max ,030229 sport sciences ,General Medicine ,Blood pressure ,chemistry ,Cardiology ,Exercise Test ,Conditioning ,business ,030217 neurology & neurosurgery - Abstract
This study examined the effects of low-intensity morning exercise (ME) on physiological response during unsteady workload evening exercise. Nine healthy men participated in the following 2 experimental conditions: 15 minutes of bicycle exercise at 40% maximum oxygen consumption (V[Combining Dot Above]O2max) in the morning (the ME condition) and rest (control [C] condition). Heart rate (HR), blood pressure (BP), temperature, oxygen uptake, and natural logarithm of high frequency, an index of cardiac parasympathetic modulation, were measured before evening exercises, which were performed for 32 minutes in 2 parts: The steady-state exercise test included three 4-min bouts of exercise at 20, 60, and 40% V[Combining Dot Above]O2max. The unsteady exercise test consisted of 4-min bouts of exercise with gradual increases and decreases in workload at 20 and 60% V[Combining Dot Above]O2max. Heart rate, BP, and oxygen uptake were measured in both experiments. Maximal and minimal values, amplitude, and phase lags were measured with each cycle of unsteady workload exercise. With steady-state exercise, HR and systolic BP at 60 and 40% V[Combining Dot Above]O2max were significantly lower in the ME condition than in the C condition. However, oxygen uptake was not significantly different between the 2 conditions. With unsteady exercise, the HR and oxygen uptake phase lags were significantly shorter and the amplitude of oxygen intake was significantly larger in the ME condition than in the C condition. There were no significant differences in physiological parameters between the conditions at rest or during recovery. The physiological response during evening exercise is enhanced by low-intensity ME, which might be an effective conditioning method on a sporting event day.
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- 2015
67. Reduction in Power Consumption for Full-Color Active Matrix Organic Light-Emitting Devices
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Kazunobu Mameno, Kenji Okumoto, Kazuki Nishimura, Nobuo Saito, Yuji Hamada, Kenichi Shibata, and Hiroshi Kanno
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Liquid-crystal display ,Physics and Astronomy (miscellaneous) ,Pixel ,business.industry ,Computer science ,General Engineering ,General Physics and Astronomy ,Viewing angle ,Active matrix ,law.invention ,AMOLED ,Optics ,law ,Filter (video) ,OLED ,RGB color model ,Optoelectronics ,business - Abstract
The active matrix organic light-emitting diode (AMOLED) is expected to serve as next generation flat panels display with the outstanding features of wide viewing angle, vivid images, and quick response. For practical use of full-color AMOLEDs in mobile devices, it is essential to reduce the power consumption, which is generally higher than that of liquid crystal displays (LCDs). For this aim, a red, green, blue, and white (RGBW) pixel format combined with an RGB color filter array (RGBW format) with a common white emission layer (EML) has been developed. We find that the RGBW format can successfully reduce the power consumption of a full-color AMOLED by nearly half that of a conventionally filtered RGB pixel format. This improved power consumption is almost equal to the power consumption of a same-sized LCD. The RGBW format is a promising technique for the further reduction of the power consumption of a full-color AMOLED.
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- 2006
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68. The relationship between the effects of elastic components of muscle and tendon in human triceps surae and decrease of oxygen uptake during rope skipping
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Hidetaka, Yamaguchi, Kenta, Yamamoto, Cihiro, Edamatsu, kouki, Takahashi, Takeshi, Miyakawa, Kazuki, Nishimura, Sho, Onodera, Department of Health Welfare and Human performance, School of Social Welfare, Kibi International University, Department of Cardiovascular Dynamics, National Cardiovascular Center Research Institute, Department of Health Sciences, Kurashiki University of Science and the Art, Foundation for Advancement of International Science(FAIS), and Department of Health and Sports Sciences, Kawasaki University of Med. Welfare
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跳躍周期 ,EMG elastic component ,oxygen uptake ,酸素摂取量 ,rope skipping ,なわとび ,弾性系 ,筋電図 ,jump frequency - Published
- 2005
69. [Untitled]
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Kazuki Nishimura
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Physical Therapy, Sports Therapy and Rehabilitation ,Orthopedics and Sports Medicine - Published
- 2005
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70. Effects of different water temperatures on rectal temperature and oxygen uptake during supine floating
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Hidetaka Yamaguchi, Youhei Nakanishi, Sho Onodera, and Kazuki Nishimura
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Animal science ,Supine position ,Degree Celsius ,Chemistry ,Water temperature ,Rectal temperature ,sense organs ,Oxygen uptake - Abstract
The purpose of this study was to determine the effects of water temperature on rectal temperature and oxygen uptake during supine floating. Eight healthy males volunteered for this study. This study was performed in a supine position at rest on land and in three water conditions (25, 30 and 35 degrees Celsius). All experiments were performed for 35 minutes. Water conditions of immersion at 25 degrees Celsius resulted in a decrease in rectal temperature and an increase in oxygen uptake. The changes in rectal temperature differed among individuals. A significant correlation was observed between changes in rectal temperature and % body fat. However, the changes in rectal temperature were affected by other factors. These data suggest that the changes in rectal temperature during immersion at 25 degrees Celsius could be affected by other factors elaborated in this paper.
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- 2004
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71. Characteristic of small-scale BESS for HOTT generation system
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Kazuki Nishimura, Shotaro Fujioka, Yasuyuki Shirai, Kei Motobayashi, and Mohammad Lutfur Rahman
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Engineering ,Wind power ,Power station ,business.industry ,Electrical engineering ,Insulated-gate bipolar transistor ,Turbine ,Compensation (engineering) ,Power (physics) ,Offshore wind power ,Control theory ,business ,Tidal power ,Physics::Atmospheric and Oceanic Physics - Abstract
Integrating a small-scale battery energy storage system (BESS) with a hybrid offshore-wind and tidal turbine (HOTT) generation system can smooth out the intermittent power generated by the offshore-wind turbine. In this system, tidal turbine is connected to an IGBT bi-directional converter and offshore-wind turbine is connected to a diode rectifier. They are connected at DC side. The power flow of tidal turbine is controlled by switching of the bi-directional converter and wind fluctuation is compensated by changing tidal turbine output. There are some problems to compensate the offshore-wind power fluctuation by the tidal output power. First, tidal turbine cannot change its output very fast because of its inertia. So there is some delay to control the output. Another problem is the loss of tidal turbine generated power due to change of the slip. However, the capacity and response speed of tidal turbine is inadequate to achieve good compensation. That's why it is required to integrate BESS with HOTT generation system to enhance reliability, increase throughput of existing grid infrastructure and yield various ancillary benefits such as to reduce system losses and improve power factor control. As a large-scale BESS is still an expensive option for renewable resources, an optimal control strategy is necessary for the use of small-scale feasible BESS. In this paper, BESS is connected to help tidal turbine to compensate fast fluctuations of offshore wind turbine. The effect of the battery is investigated through simulations. This is a small capacity simulation study which is prepared to use in our small experimental model HOTT system with BESS.
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- 2014
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72. OS0617 Simulation of fracture path prediction in functionally graded materials
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Kazuki Nishimura, Takehiro Fujimoto, and Toshihisa Nishioka
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business.industry ,Path (graph theory) ,Fracture (geology) ,Structural engineering ,business ,Geology - Published
- 2009
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73. Quantitative and in situ detection of oxidatively generated DNA damage 8,5'-cyclo-2'-deoxyadenosine using an immunoassay with a novel monoclonal antibody
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Toshio Mori, Philip J. Brooks, Takaaki Iwamoto, Tomohisa Nishiwaki, Kazuki Nishimura, Shigeki Sugiura, and Nobuhiko Kobayashi
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Xeroderma pigmentosum ,DNA damage ,Pyrimidine dimer ,Biology ,Biochemistry ,chemistry.chemical_compound ,Mice ,Deoxyadenosine ,Cell Line, Tumor ,medicine ,Animals ,Humans ,Physical and Theoretical Chemistry ,Immunoassay ,Hybridomas ,Deoxyadenosines ,Molecular Structure ,Oligonucleotide ,2'-deoxyadenosine ,Antibodies, Monoclonal ,General Medicine ,medicine.disease ,Molecular biology ,chemistry ,Gene Expression Regulation ,DNA ,Nucleotide excision repair ,DNA Damage - Abstract
Xeroderma pigmentosum (XP) is a genetic disorder associated with defects in nucleotide excision repair, which eliminates a wide variety of helix-distorting types of DNA damage including sunlight-induced pyrimidine dimers. In addition to skin disease, approximately 30% of XP patients develop progressive neurological disease, which has been hypothesized to be associated with the accumulation of a particular type of oxidatively generated DNA damage called purine 8,5'-cyclo-2'-deoxynucleosides (purine cyclonucleosides). However, there are no currently available methods to detect purine cyclonucleosides in DNA without the need for DNA hydrolysis. In this study, we generated a novel monoclonal antibody (CdA-1) specific for purine cyclonucleosides in single-stranded DNA that recognizes 8,5'-cyclo-2'-deoxyadenosine (cyclo-dA). An immunoassay using CdA-1 revealed a linear dose response between known amounts of cyclo-dA in oligonucleotides and the antibody binding to them. The quantitative immunoassay revealed that treatment with Fenton-type reagents (CuCl(2)/H(2)O(2)/ascorbate) efficiently produces cyclo-dA in DNA in a dose-dependent manner. Moreover, immunofluorescent analysis using CdA-1 enabled the visualization of cyclo-dA in human osteosarcoma cells, which had been transfected with oligonucleotides containing cyclo-dA. Thus, the CdA-1 antibody is a valuable tool for the detection and quantification of cyclo-dA in DNA, and may be useful for characterizing the mechanism(s) underlying the development of XP neurological disease.
- Published
- 2013
74. Proposal of the performance evaluation method for a MIMO antenna
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Kouhei Itou, Kazuki Nishimura, Shigeki Takeda, and Kenichi Kagoshima
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3G MIMO ,Computer science ,ComputerSystemsOrganization_COMPUTER-COMMUNICATIONNETWORKS ,MIMO ,Astrophysics::Instrumentation and Methods for Astrophysics ,Data_CODINGANDINFORMATIONTHEORY ,MIMO-OFDM ,Precoding ,Multi-user MIMO ,Antenna efficiency ,Spatial multiplexing ,Hardware_GENERAL ,Electronic engineering ,Antenna (radio) ,Computer Science::Information Theory - Abstract
This paper has proposed the evaluation method of the MIMO antenna performance including frequency characteristics. Since the performance of the MIMO antenna depends on both radiation efficiency and correlation coefficient, the task for evaluating the antenna, especially including frequency characteristic is heavy and time consuming.
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- 2012
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75. Enhancement of the frequency characteristics of a decoupling and matching feeding network for a MIMO antenna
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Kazuki Nishimura, Atsuhiro Kagaya, Kenichi Kagoshima, and S. Takeda
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Loop antenna ,Computer science ,law ,Antenna measurement ,Electronic engineering ,Antenna factor ,Antenna noise temperature ,Dipole antenna ,Antenna tuner ,Computer Science::Information Theory ,Antenna efficiency ,Radiation pattern ,law.invention - Abstract
In order to enhance the bandwidth of the radiation efficiency of a MIMO antenna using a decoupling and matching feeding network, a new design formula of the DMFN elements which can match the antenna conductance to the terminal loads with different value. The unitary matrix in the design formula of the DMFN, which can equalize the bandwidth of each feeding terminal has been derived. It has been also evaluated how the imaginary part of the antenna admittance affect to the bandwidth of the radiation efficiency.
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- 2011
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76. An array antenna for MIMO systems with a decoupling network using bridge susceptances
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Atsuhiro Kagaya, Kenichi Kagoshima, Shigeki Obote, Kazuki Nishimura, and Nobuyuki Endo
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3G MIMO ,Approximation theory ,Electric power transmission ,business.industry ,Computer science ,Electronic engineering ,Wireless ,Telecommunications ,business ,Mimo communication ,Multi-user MIMO ,Decoupling (electronics) ,Mimo systems - Abstract
Decoupling and matching feeding networks are considerably interested in small wireless terminals to enhance their abilities for MIMO systems. In various proposals of DMFN's, the feeding networks composed of bridge susceptances and transmission lines are simple. However, this DMFN has only been applied to the limited array with special characteristics. This paper presents general design formulas of the DMFN for the two elements and three elements arrays and fundamental numerical data are presented to assure the validity of the design formulas.
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- 2011
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77. Distinct DNA methylation patterns of lysophosphatidic acid receptor genes during rat hepatocarcinogenesis induced by a choline-deficient L-amino acid-defined diet
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Toshifumi Tsujiuchi, Ikuma Yoshida, Mai Hayashi, Kazuki Nishimura, Nobuyuki Fukushima, and Kyoko Okabe
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Male ,Carcinoma, Hepatocellular ,Health, Toxicology and Mutagenesis ,Bisulfite sequencing ,Biology ,Toxicology ,medicine.disease_cause ,chemistry.chemical_compound ,Lysophosphatidic acid ,medicine ,Animals ,Receptors, Lysophosphatidic Acid ,Receptor ,Gene ,Liver Neoplasms ,General Medicine ,Methylation ,HCCS ,DNA Methylation ,Molecular biology ,Rats, Inbred F344 ,Choline Deficiency ,Diet ,Rats ,Gene Expression Regulation, Neoplastic ,chemistry ,Liver ,DNA methylation ,Carcinogenesis - Abstract
Altered expressions of lysophosphatidic acid (LPA) receptor genes have been reported in tumor cells of human and rats. Recently, we detected the frequent mutations of LPA receptor-1 (LPA1) gene in rat hepatocellular carcinomas (HCCs) induced by a choline-deficient l-amino acid-defined (CDAA) diet. In this study, the DNA methylation patterns of LPA receptor genes and their expression levels during rat hepatocarcinogenesis induced by the CDAA diet were investigated. Six-week-old F344 male rats were continuously fed with the CDAA diet, and animals were then killed at 7 days and 2, 12, 20, and 75 weeks, respectively. Genomic DNAs were extracted from livers and HCCs for the assessment of methylation status by bisulfite sequencing, comparing to normal livers. The livers of rats fed the CDAA diet were unmethylated in LPA1 and LPA2 genes as well as normal livers. In LPA3 gene, although normal livers were unmethylated, the livers at 7 days and 2 and 12 weeks weakly or moderately methylated and those at 20 weeks markedly methylated. Moreover, 4 HCCs were completely methylated in LPA3 gene. Expression levels of LPA receptor genes in the livers of rats fed the CDAA diet and HCCs were correlating with DNA methylation status. These results indicate that DNA methylation status of the LPA3 gene was disturbed in the livers of rats fed the CDAA diet and established HCCs, suggesting that alterations of the LPA receptor genes might be involved during rat hepatocarcinogenesis induced by the CDAA diet.
- Published
- 2010
78. Circadian variations in anaerobic threshold
- Author
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Kazuki Nishimura, Koji Nagasaki, Hidetaka Yamaguchi, Akira Yoshioka, Yuka Nose, Sho Onodera, Noboru Takamoto, Kazuki Nishimura, Koji Nagasaki, Hidetaka Yamaguchi, Akira Yoshioka, Yuka Nose, Sho Onodera, and Noboru Takamoto
- Abstract
This study aimed to determine whether certain respiratory and cardiovascular parameters associated with anaerobic threshold (AT), measured during graded exercise testing, occur at lower intensities in the morning than in the evening. Ten healthy Japanese men volunteered to participate in this study, which involved two conditions that were performed at different times of day: morning (M) exercise was performed between 9:00 and 10:00 a.m., and afternoon (A) exercise was performed between 4:00–6:00 p.m. After resting supine for 30 minutes, each subject performed graded cycle ergometer exercise testing comprising 90-second stages. Exercise intensity was initially 10 W and was increased by 10 W for each stage. Heart rate (HR), blood pressure (BP), absolute double product (DP), cardiac autonomic nervous system modulation, and ventilatory volume (VE) were measured during each exercise stage. Ventilatory threshold (VT), the double product breaking point (DPBP), and breaking point of the natural log of high frequency (ln HF) (HFBP) were reached at a lower exercise intensity in the M condition than in the A condition (p<.05). Values for VE at VT intensity, DP, HR, and systolic blood pressure (SBP) at DPBP were significantly lower in the M condition than in the A condition (p<.05). These data suggest that AT is reached at a lower intensity in the morning than in the afternoon, and that relative burden, as indicated by HR and SBP, is greater in the morning than in the afternoon. Exercise prescriptions that incorporate awareness of the circadian rhythms may prevent cardiac or cerebrovascular accidents during exercise.
- Published
- 2014
79. Influence of defects on photoluminescence in C 60 crystals
- Author
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Masaru Tachibana, Kazuki Nishimura, Takeshi Komatsu, Kenichi Kojima, and Takaaki Sunakawa
- Subjects
Crystallography ,Materials science ,Quality (physics) ,Photoluminescence ,Condensed matter physics ,Etching ,Deformation (meteorology) ,Luminescence ,Crystallographic defect ,Spectral line ,Intensity (heat transfer) - Abstract
Photoluminescence spectra of C60 crystals with high quality was measured before and after the mechanical deformation . New peak at 685 nm appeared after the deformation. The peak was observed only at temperatures lower than about 90 K, where its intensity decrease with increasing temperature. The temperature dependence of the peak intensity was correlated with that of main other peak at 735 nm, which would originate in intrinsic C60 crystals. From these result, the origin of the peak at 685 nm is discussed in the light of crystal defects, especially dislocations.© (1997) COPYRIGHT SPIE--The International Society for Optical Engineering. Downloading of the abstract is permitted for personal use only.
- Published
- 1997
- Full Text
- View/download PDF
80. 23.2: New Green and Red Phosphorescent Host Materials for Highly-Efficient and Long-Lifetime OLEDs
- Author
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Hiroshi Yamamoto, Toshihiro Iwakuma, Yukitoshi Jinde, Tomoki Kato, Yuichiro Kawamura, Chishio Hosokawa, Toshinari Ogiwara, Kazuki Nishimura, Masaki Numata, and Masahiro Kawamura
- Subjects
Materials science ,business.industry ,Power consumption ,OLED ,Optoelectronics ,Luminous efficacy ,business ,Phosphorescence ,Fluorescence ,Luminance ,Host (network) ,Common emitter - Abstract
We successfully found new phosphorescent host materials. Red host material PRH-01 with a red phosphorescent emitter achieved very high performance of 4.9 V, current efficiency of 20.2 cd/A and half lifetime of 150,000 hrs at an initial luminance of 1,000 cd/m2. We designed new molecular structure of green host material focusing on electron transport property and newly developed material PGH-01 achieved very high performance of 5.3 V, 71.9 cd/A and half lifetime of 150,000 hrs at an initial luminance of 1,000 cd/m2. It was confirmed by simulation that these host materials have great potential to reduce power consumption of full-color OLED displays. We also studied hybrid white OLEDs with combining the latest blue fluorescent material and the phosphorescent materials. High luminous efficacy of about 30 lm/W and long lifetime over 200,000 hrs at an initial luminance of 1,000 cd/m2 without any light outcoupling structure were successfully obtained.
- Published
- 2009
- Full Text
- View/download PDF
81. P-203: The Improvement of White OLED's Performance
- Author
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Kenichi Fukuoka, Yukitoshi Jinde, Hiroshi Yamamoto, Nobuhiro Yabunouchi, Toshihiro Iwakuma, Takashi Arakane, Kazuki Nishimura, Masakazu Funahashi, Masahiro Kawamura, and Chishio Hosokawa
- Subjects
Host material ,Materials science ,Dopant ,Power consumption ,business.industry ,Color gel ,Fluorescent materials ,OLED ,Optoelectronics ,business ,Phosphorescence ,Voltage - Abstract
We have researched further improvement upon three-component white OLED devices with using fluorescent materials disclosed in SID'07. The long lifetime over 70,000hr@1,000cd/m2 maintaining at a high efficiency of 20cd/A was achieved by optimization of a carrier balance with using new carrier transport materials. Performance of blue and red OLEDs were also developed in order to enhance capability of white OLEDs, respectively. A long lifetime of 50,000hr@1,000cd/m2 was achieved by a new light blue dopant BD-5. Meanwhile, we studied phosphorescent materials for the red device to progress towards further low power consumption. A low driving voltage of 4.4V at 10mA/cm2 and a long lifetime of 100,000hr@1,000cd/m2 were realized by employing a new host material and new carrier transport materials. These materials will contribute to large-Size OLED TVs with color filter method or lighting application for practical use.
- Published
- 2008
- Full Text
- View/download PDF
82. High Efficiency Stacked Organic Light-Emitting Diodes Employing Li2O as a Connecting Layer
- Author
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Kazunobu Mameno, Nobuo Saito, Hiroshi Kanno, Kenji Okumoto, Hisakazu Takahashi, Kazuki Nishimura, Yuji Hamada, Kenichi Shibata, and Hiroki Ishida
- Subjects
Materials science ,business.industry ,General Engineering ,General Physics and Astronomy ,Luminance ,Stack (abstract data type) ,Backplane ,Thin-film transistor ,OLED ,Optoelectronics ,business ,Layer (electronics) ,Electrical efficiency ,Diode - Abstract
We demonstrate the high-efficiency stacked organic light-emitting diodes (OLEDs) introducing new connecting layers. In the green stacked OLEDs, the external efficiencies increase proportionally to the number of the stacked units without suffering the decrease in power efficiency. The current, power and external efficiencies at 0.5 mA/cm2 of the stacked OLED with six stacked units (6-stacked OLED) have reached 235 cd/A, 46.6 lm/W, and 65.8%, respectively. Furthermore, we have applied the connecting layers to a white stacked OLED and fabricated an active-matrix full-color display with a low temperature polysilicon thin film transistor backplane. In the device, the current efficiency of the white 2-stacked OLED is enhanced by a factor of 2.2. The initial luminance drop is significantly suppressed for the white 2-stacked OLED compared to 1-stacked OLED. The proposed white stacked OLED technology can be applied to a full-color display for a practical use.
- Published
- 2006
- Full Text
- View/download PDF
83. Effects of periodic hypobaric and hypoxic environment systems on glucose metabolism during endurance exercise.
- Author
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Kazuki NISHIMURA and Koji NAGASAKI
- Abstract
Purpose: The present study aimed to determine the relationship between exercise in the periodic hypobaric hypoxic environment (PHHE) and physiological responses evaluated using an oral glucose tolerance test . Methods : This study included 13 healthy men. They provided written informed consent. All subjects performed an oral glucose tolerance test for 120 minutes and exercise tests. The exercise test started 30 minutes after oral glucose tolerance test. The exercise tests consisted of 40% maximal oxygen intake for 18 minutes, We established three experimental conditions: exercise in PHHE system (periodic), at an altitude of 750 in (fixed), and at an attitude of 0 m (control). The periodic condition varied between decreased pressure at an altitude of 1,500 m for 180 seconds and increased pressure at an altitude of 0 m for 180 seconds. Pulse rate (PR). blood pressure (BP), arterial oxygen saturation (SpO
2 ). and blood glucose values were measured during the oral glucose tolerance test. Heart rate (HR). SpO2 , and the rating of perceived exertion (RPE) were measured during exercise. Results and Discussion: SpO2 was significantly lower in the periodic condition, PR, and systolic BP were significantly different among the 3 conditions. There were no significant differences in blood glucose values among the 3 conditions. During exercise, HR and RPE were not significantly different. These data suggested that glucose metabolism was not suppressed by endurance exercise in the PHHE. [ABSTRACT FROM AUTHOR]- Published
- 2022
84. Relationship between prolonged expiration and the physiological responses during low intensity exercise.
- Author
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Kazuki NISHIMURA, Yutaro TAMARI, Sho ONODERA, and Koji NAGASAKI
- Abstract
Purpose: The present study aimed to determine the effects of prolonged expiration on the physiological responses during low intensity exercise and after exercise. Methods: This study included 10 healthy men. They provided written informed consent. All participants performed a cycling exercise for 15 minutes. The participants recovered after exercise by laying in the supine position for 10 minutes. Exercise intensity was set to 20% maximum oxygen intake. We established two experimental conditions according to the breathing rhythms during the exercise: namely, 3-second inspiration paired with 7-second expiration (prolonged expiration; PE) and normal breathing (control; C). The heart rate (HR), natural log of high frequency in HR variability (ln HF), blood pressure (BP), and respiratory responses were measured under both conditions. Results: During exercise, the HR was significantly lower in the PE condition than in the C condition. However, the BP, and respiratory responses did not show a significant difference between the conditions. After exercise, the HR significantly decreased, while ln HF was significantly higher in the PE condition. The respiration rate, ventilatory volume, and ventilatory equivalent were significantly lower in the PE condition. Discussion: These data suggested that the prolonged expiration during low-intensity exercise decreased the HR, enhanced promoted of the cardiac parasympathetic nervous system, and increased the oxygen ventilation efficiency. [ABSTRACT FROM AUTHOR]
- Published
- 2021
85. Comparison of physiological responses during unsteady slope treadmill walking between spring and autumn.
- Author
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Kazuki Nishimura, Yutaro Tamari, Sho Onodera, and Koji Nagasaki
- Abstract
Purpose: The present study aimed to determine the effects of circannual variations in physiological responses during unsteady slope treadmill walking. Methods: The study included 11 healthy men who provided written informed consent before participation. The study was performed in spring and autumn. Each subject was walked for 32 min in two parts. The steady-state exercise test included three 4-min bouts of walk at 0°, 16°, and 8° at slope, whereas the unsteady workload exercise test consisted of 4-min bouts of exercise with gradual increases and decreases in workload at 0° and 16° at slope. The walking speed set of 25% of peak oxygen uptake. Heart rate (HR) and rating of perceived exertion (RPE) were measured in both experiments. Maximal and minimal values, amplitude, and phase lags were measured. Results and Discussion: At rest, there were no significant differences in HR, In HF, and blood pressure between two conditions. However, the oral temperature was significantly higher in the spring condition. The HR during exercise was higher in the spring condition compared to those in autumn condition. However, RPE during exercise was lower in the spring condition. The HR phase lags and amplitude were no significant difference in the two conditions. These data suggested that the human adaptability to unsteady slope treadmill walking was comparable between spring and autumn. [ABSTRACT FROM AUTHOR]
- Published
- 2020
86. Synthesis and characterization of mist chemical vapor deposited aluminum titanium oxide films.
- Author
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Zenji Yatabe, Koshi Nishiyama, Takaaki Tsuda, Kazuki Nishimura, and Yusui Nakamura
- Abstract
Aluminum titanium oxide (Al
1–x Tix Oy , an alloy of Al2 O3 and TiO2 ), an attractive high-κ dielectric material, was synthesized by mist chemical vapor deposition, utilizing Al2 O3 and TiO2 precursors. X-ray diffraction investigations revealed that the Al1–x Tix Oy (0 < x < 0.72) films deposited at 400 °C have an amorphous-phase structure. It was found that the bandgap of the Al1–x Tix Oy films decreases with increasing Ti composition. Moreover, the obtained refractive index, mass density and bandgap of Al2 O3 and TiO2 films are all comparable to those reported for high-quality Al2 O3 and TiO2 films deposited by atomic layer deposition. [ABSTRACT FROM AUTHOR]- Published
- 2019
- Full Text
- View/download PDF
87. Solution electrochemiluminescent cell with a high luminance using an ion conductive assistant dopant
- Author
-
Takashi Fuyuki, Tsuyoshi Tsujioka, Shigeki Matsuta, Yuji Hamada, Kenichi Shibata, and Kazuki Nishimura
- Subjects
chemistry.chemical_compound ,chemistry ,Dopant ,Electrode ,General Engineering ,Analytical chemistry ,General Physics and Astronomy ,Electroluminescence ,Acetonitrile ,Rubrene ,Luminous efficacy ,Luminance ,Ion - Abstract
Conventional solution electrochemiluminescent (SECL) cells have a low luminance. In this paper, we propose an ion conductive assistant dopant (ICAD) system to improve the luminance of SECL cells. The SECL cell is assumed to have a simple structure of [transparent electrode/emitting solution/transparent electrode]. The solution of the cell consists of a mixed solvent (o-dichlorobenzene/acetonitrile=2/1 (vol/vol)), rubrene used as the emitting material, and 1,2-diphenoxyethane used as the ICAD. When voltage is applied to this SECL cell, the cell achieves a luminance of 183 cd/m2 and a luminous efficiency of 1.5 cd/A at 8 V with yellow emission. On the other hand, an SECL cell without an ICAD results in a low luminance of 0.3 cd/m2 at 8 V, corresponding to a conventional SECL cell. The ICAD improves the luminance 600 times by enhancing the ion conduction of rubrene cations in the solution. Furthermore, when the mixed solvent (o-dichlorobenzene/toluene=2/1 (vol/vol)), which has a high voltage resistance, is used in the SECL cell, the cell obtains a maximum luminance of 986 cd/m2 at 80 V. The features of the SECL cell are a simple cell structure and a transparent emitting area. SECL cells are expected to be used in unique displays with a see-through function for automobiles, windows, information equipment, and so on.
88. Circadian variations in anaerobic threshold
- Author
-
Kazuki Nishimura, Nagasaki, K., Yamaguchi, H., Yoshioka, A., Nose, Y., Onodera, S., and Takamoto, N.
- Subjects
circadian rhythm ,cardiac autonomic nervous system ,double product ,ventilatory volume - Abstract
This study aimed to determine whether certain respiratory and cardiovascular parameters associated with anaerobic threshold (AT), measured during graded exercise testing, occur at lower intensities in the morning than in the evening. Ten healthy Japanese men volunteered to participate in this study, which involved two conditions that were performed at different times of day: morning (M) exercise was performed between 9:00 and 10:00 a.m., and afternoon (A) exercise was performed between 4:00–6:00 p.m. After resting supine for 30 minutes, each subject performed graded cycle ergometer exercise testing comprising 90-second stages. Exercise intensity was initially 10 W and was increased by 10 W for each stage. Heart rate (HR), blood pressure (BP), absolute double product (DP), cardiac autonomic nervous system modulation, and ventilatory volume (VE) were measured during each exercise stage. Ventilatory threshold (VT), the double product breaking point (DPBP), and breaking point of the natural log of high frequency (ln HF) (HFBP) were reached at a lower exercise intensity in the M condition than in the A condition (p
89. Solution electrochemiluminescent cell using tris(phenylpyridine) iridium
- Author
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Kazuki Nishimura, Tsuyoshi Tsujioka, Yuji Hamada, Kenichi Shibata, and Takashi Fuyuki
- Subjects
Tris ,General Engineering ,Analytical chemistry ,General Physics and Astronomy ,chemistry.chemical_element ,Electroluminescence ,Photochemistry ,Solvent ,chemistry.chemical_compound ,Benzonitrile ,chemistry ,Electrode ,Electrochemiluminescence ,Iridium ,Luminous efficacy - Abstract
A solution electrochemiluminescent (SECL) cell is an emitting device that employs one type of emitting solution. In this study, tris(2-phenylpyridine) iridium [Ir(ppy)3], a well-known emitting material in organic electroluminescent cells, was used in a SECL cell. The cell had a simple structure of transparent electrode/emitting solution/transparent electrode. The solution consisted of benzonitrile used as the solvent, and Ir(ppy)3 used as the emitting material. When voltage was applied to this SECL cell, green emission was produced with a peak wavelength of 530 nm, which originated from Ir(ppy)3. This SECL cell showed a maximum luminance of 3 cd/m2 and a luminous efficiency of 0.014 cd/A. The features of the SECL cell are a simple cell structure and a transparent emitting area. SECL cells are expected to be used in unique displays with a see-through function for automobiles, windows, information displays, and so forth.
90. Effects of backpack loading on physiological responses during unsteady slope treadmill walking.
- Author
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Kazuki Nishimura, Takehiko Takmoaoto, Sho Onodera, and Noboru Takamoto
- Abstract
Purpose: The present study aimed to identify the relationship between backpack loading and physiological responses during unsteady slope treadmill walking. Methods: This study included 11 healthy men who provided written informed consent. The study was performed under two different conditions of backpack loading (% body weight): 0% and 15%. Each participant walked for 32 minutes in two sections. The steady-state exercise test included three 4-minute bouts of walking at 0°, 14°, and 7° slopes, whereas the unsteady workload exercise test consisted of 4-minute bouts of exercise with gradual increases and decreases in workload at 0° and 14° slopes. The walking speed was set at 25% of the peak oxygen uptake (VO
2 ). Heart rate (HR) and VO2 were measured in both experiments. Maximal and minimal values, amplitude, and phase lags were measured during each cycle of unsteady slope walking. Results/Discussion: HR and VO2 during exercise were significantly higher in the 15% condition than in those in the 0% condition. During the unsteady workload exercise, the HR and VO2 phase lags during maximum and minimum slopes were significantly longer in the 15% condition. Additionally, the HR and VO2 amplitude were significantly lower in the 15% condition. These data suggest that unsteady slope treadmill walking can assess the human adaptability to physiological responses. The heavy backpack loading delayed the capability of the physiological response. [ABSTRACT FROM AUTHOR]- Published
- 2017
91. Association between circannual variations and physiological responses during unsteady workload exercise.
- Author
-
Kazuki Nishimura, Hidetaka Yamaguchi, Akira Yoshioka, Koji Nagasaki, and Sho Onodera
- Abstract
Purpose: The present study aimed to determine the relationship between circannual variations and physiological responses during unsteady workload exercise. Methods: We included 14 healthy men, who provided written informed consent before participation. The study was performed under two conditions: summer (S) and winter (W). Each subject was performed for 32 min in two parts. The steady-state exercise test included three 4-min bouts of exercise at 20%, 60%, and 40% VO
2 max, whereas the unsteady workload exercise test consisted of 4-min bouts of exercise with gradual increases and decreases in workload at 20% and 60% V02max. Heart rate (HR), blood pressure (BP), and rate of perceived exertion (RPE) were measured in both experiments. Maximal and minimal values, amplitude, and phase lags were measured during each cycle of unsteady workload exercise. Results and Discussion: Resting BP was significantly higher in the S condition than in the W condition. HR and RPE during exercise were significantly higher in the S condition compared to those in the W condition. With unsteady workload exercise, the HR phase lags during maximum and minimum workload were significantly longer in the S condition compared to those in the W condition. Exercise prescriptions that incorporate an awareness of the human circannual rhythm may prevent cardiac and cerebrovascular accidents during exercise. [ABSTRACT FROM AUTHOR]- Published
- 2016
92. Characteristics of circadian variations of the body temperature and grip strength.
- Author
-
Hidetaka Yamaguchi, Terumasa Takahara, Kazutoshi Seki, Kazuki Nishimura, Sho Onodera, and Kuniatsu Nagami
- Abstract
Purpose: The study aimed to examine the relationship between the circadian rhythms of the body temperature and grip strength. Methods: The subjects were 14 healthy adult males. The measurements were conducted at 9:00, 16:00, 18:00, 20:00 and 22:00. The oral temperature, heart rate, and grip strength were measured in this order. The grip strength was measured twice, and the better score was adopted as the representative value. The time for rest between the performances was two minutes or longer. Measurements were randomly conducted on different days. There were no restrictions on the physical activities of the subjects except during the measurements. Results and Discussion: At 9:00, the body temperature was significantly lower and the grip strength was weaker than those during other time periods. At 20:00, the body temperature was the highest and the grip strength was the strongest. This suggests that there were delays in the peak hours of the body temperature and maximum muscle strength in the present study compared to those reported in previous studies. The results of the present study suggest that the circadian rhythm, or peak hours, of the grip strength may be related to changes in the body temperature. [ABSTRACT FROM AUTHOR]
- Published
- 2015
93. Effects of morning exercise on postexercise physiological responses.
- Author
-
Kazuki Nishimura, Koji Nagasaki, Hidetaka Yamaguchi, Akira Yoshioka, Sho Onodera, and Noboru Takamoto
- Abstract
Purpose: The present study aimed to determine the relationship between low-intensity exercise in the morning and post-exercise physiological responses in humans. Methods: This study included 9 healthy men who provided written informed consent for participation. The study was performed under 2 conditions: the exercise (E) condition and the control (C) condition. In the E condition, the participants performed cycling exercises for 15 min at 0830 hours. The exercise intensity was adjusted to 40% of maximum oxygen uptake. In the C condition, the participants did not perform any exercise in the morning. The heart rate (HR), In HF, blood pressure (BP), double product (DP), and oral temperature were first recorded at 0700 hours and then every hour from 0700 to 1600 hours. Results and Discussion: Changes in all 5 parameters showed no significant differences between 2 conditions. However, At 0900 hours, the HR and DP in the E condition were significantly higher than those in the C condition. All participants had their physiological parameters measured in the same room and ate the same meal, whereby the effects of factors other than morning exercise were minimized. Thus, the impact of morning exercise may be small compared to diurnal fluctuations in physiological responses. In conclusion, low-intensity exercise in the morning has little effect on post-exercise physiological responses. [ABSTRACT FROM AUTHOR]
- Published
- 2015
94. Changes in relative exercise intensity during a two hour endurance race using a tandem-bicycle for exercise.
- Author
-
Sho Onodera, Sotaro Hayashi, Takuma Wada, Noboru Yoshida, Yutaro Tamari, Megumi Murata, Hidetaka Yamaguchi, Akira Yoshioka, Kazuki Nishimura, and Nozomi Matsumoto
- Abstract
Purpose: The purpose of this study was to clarify the relative exercise intensity during tandem-bicycle exercise in two hours endurance race. Methods: Two healthy male subjects (the front saddle: age; 23yrs, height; 173 cm, body weight; 80 kg, peak oxygen uptake; 43.9 ml/kg/min, the rear saddle: height; 161 cm, body weight; 72 kg, peak oxygen uptake; 45.1 ml/kg/min) volunteered for this study. Measurement items were RPE, heart rate, blood pressure and rectal temperature. They performed ten laps around a 3.7 kilometer track. The temperature and humidity were 5 degrees Celsius and 57 percent. Results: The average speed was 21.9 km/h of one track. The average relative oxygen uptake (%V02peak) of the front and rear saddle were 77.6 % ± 5.8 and 72.6% ± 5.8. Discussion: It was considered the difference in front and rear saddle was about six present of relative exercise intensity. Conclusion: The relative exercise intensity of the front saddle was higher than that of the rear saddle. [ABSTRACT FROM AUTHOR]
- Published
- 2015
95. Effects of Menstrual Cycle Phase on Fluid Regulation during Walking Exercise.
- Author
-
Yuka Nose, Kana Fujita, Takuma Wada, Kazuki Nishimura, and Masayuki Hakoda
- Subjects
- *
ANALYSIS of variance , *BODY fluids , *EXERCISE , *EXERCISE physiology , *HEART beat , *SEX hormones , *LUTEAL phase , *MENSTRUAL cycle , *T-test (Statistics) , *WALKING , *RENIN-angiotensin system , *BODY mass index , *DATA analysis software , *DESCRIPTIVE statistics - Abstract
To elucidate the fluid regulation in different menstrual cycle phases during exercise. Sex hormones affect fluid regulation in different ways. Moreover, the renin angiotensin-aldosterone system is activated in the luteal phase in rest. However, there are limited studies on fluid regulation affected by such hormone excretion in the menstrual cycle during exercise, especially during a light walking exercise. A non-invasive method using urine samples to determine menstrual cycle phases was used, and the follicular and luteal phases were successfully confirmed in 10 participants (age, 21 ± 1 years; body mass index, 20.5 ± 2.1 kg/m²). The experimental exercise sessions consisted of 5-min standing and 15-min walking at 2 km/h on 15% slope (approximately 8.3°) on a treadmill. Each participant carried a backpack weighing 5% of her own weight, and performed three sessions of walking exercise. Urine aldosterone excretion was significantly higher in the luteal than in the follicular phase before and after walking (p < 0.05). Urinary excretion of aldosterone was five times higher in the luteal than in the follicular phase before and after walking exercise. Heart rates during walking, after rest, and after recovery were all significantly higher in the luteal than in the follicular phase (p < 0.05). The participants' ratings of perceived exertion during the first and third session of walking in the luteal phase was not higher than that at the follicular phase. The results of our study suggested that increased activity of the renin-angiotensin-aldosterone system in the luteal phase of the menstrual cycle might be further activated during exercise. This may increase the circulatory load, which is reflected as increased heart rate. These results suggested that premenopausal women may better take into account a possibility of an increased circulatory load in the luteal phase even when they perform light exercise. [ABSTRACT FROM AUTHOR]
- Published
- 2020
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