51. Assessing the quality of reports of randomized trials in pediatric complementary and alternative medicine
- Author
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David Moher, Isabelle Gaboury, Margaret Sampson, Kaitryn Campbell, Brian Berman, William Beckner, and Leah Lepage
- Subjects
Complementary Therapies ,medicine.medical_specialty ,Canada ,Quality Assurance, Health Care ,media_common.quotation_subject ,Alternative medicine ,Psychological intervention ,Information Storage and Retrieval ,Pediatrics ,law.invention ,paediatrics ,03 medical and health sciences ,0302 clinical medicine ,Alternative and Complementary Medicine ,Randomized controlled trial ,law ,medicine ,Humans ,Quality (business) ,Pediatrics, Perinatology, and Child Health ,030212 general & internal medicine ,Program Development ,Adverse effect ,Child ,media_common ,Randomized Controlled Trials as Topic ,business.industry ,lcsh:RJ1-570 ,lcsh:Pediatrics ,Evidence-based medicine ,Jadad scale ,Checklist ,3. Good health ,030220 oncology & carcinogenesis ,Family medicine ,Population Surveillance ,Pediatrics, Perinatology and Child Health ,business ,Library and Information Science ,complementary and alternative medicine ,Research Article - Abstract
Objective To evaluate the quality of reports of complementary and alternative medicine (CAM) randomized controlled trials (RCTs) in the pediatric population. We also examined whether there was a change in the quality of reporting over time. Methods We used a systematic sample of 251 reports of RCTs that used a CAM intervention. The quality of each report was assessed using the number of CONSORT checklist items included, the frequency of unclear allocation concealment, and a 5-point quality assessment instrument. Results Nearly half (40%) of the CONSORT checklist items were included in the reports, with an increase in the number of items included. The majority (81.3%) of RCTs reported unclear allocation concealment with no significant change over time. The quality of reports achieved approximately 40% of their maximum possible total score as assessed with the Jadad scale with no change over time. Information regarding adverse events was reported in less than one quarter of the RCTs (22%) and information regarding costs was mentioned in only a minority of reports (4%). Conclusions RCTs are an important tool for evidence based health care decisions. If these studies are to be relevant in the evaluation of CAM interventions it is important that they are conducted and reported with the highest possible standards. There is a need to redouble efforts to ensure that children and their families are participating in RCTs that are conducted and reported with minimal bias. Such studies will increase their usefulness to a board spectrum of interested stakeholders.
- Published
- 2002