15,623 results on '"K. Ito"'
Search Results
52. 46P Multi-center, phase II study of docetaxel (DTX) plus ramucirumab (RAM) following platinum-based chemotherapy plus ICIs in patients with NSCLC: SCORPION study
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R. Matsuzawa, M. Morise, K. Ito, O. Hataji, K. Takahashi, Y. Kuwatsuka, Y. Goto, K. Imaizumi, H. Itani, T. Yamaguchi, Y. Zenke, M. Oki, and M. Ishii
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Pulmonary and Respiratory Medicine ,Oncology - Published
- 2023
53. WCN23-0367 The Cases withheld Renal Replacement Therapy at a Regional General Hospital in Japan
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H. MORI, K. Tabei, K. Ito, Y. Kaku, S. Ookawara, and Y. Morishita
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Nephrology - Published
- 2023
54. Examining how preferences for employer branding attributes differ from entry to exit and how they relate to commitment, satisfaction, and retention
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K. Ito, Jack, M. Brotheridge, Céleste, and McFarland, Kathie
- Published
- 2013
- Full Text
- View/download PDF
55. A single oral supplementation of nicotinamide within the daily tolerable upper level increases blood NAD+ levels in healthy subjects
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Zinat Tamannaa, Mitsutoshi Setou, Keiichi Odagiri, Yusuke Takanashi, Takashi K. Ito, Tomohito Sato, and Takuya Kitamoto
- Subjects
Vitamin ,Aging ,medicine.medical_specialty ,Physiology ,Blood lipids ,Nicotinamide adenine dinucleotide ,Lipidome ,chemistry.chemical_compound ,Internal medicine ,NAD+ ,Medicine ,Nicotinamide ,business.industry ,Healthy subjects ,Cell Biology ,Multiple species ,Clinical trial ,Endocrinology ,chemistry ,Composition (visual arts) ,Neurology (clinical) ,NAD+ kinase ,Geriatrics and Gerontology ,business - Abstract
A decrease in nicotinamide adenine dinucleotide (NAD+) levels is a hallmark of aging in multiple species, including humans. Our previous clinical trial showed that supplementation of 200 mg nicotinamide, a form of vitamin B3, increased blood NAD+ levels. Here we report a clinical trial to assess the efficacy of a lower and a higher dose nicotinamide on increasing NAD+ levels. Blood NAD+ levels were evaluated before and after treatment of 100 mg nicotinamide, 500 mg nicotinamide, or water only. The three treatment arms were tested in the same cohort of 5 healthy adults. Oral supplementation of 500 mg nicotinamide led to a significant increase in blood NAD+ after 12 h and showed a trend of increase after 48 h (P = 0.056), whereas 100 mg nicotinamide or water intake only did not change the NAD+ levels in the same subjects. Blood lipidome analysis showed that the levels of 277 lipid species significantly changed after 12 h among 1463 species detected, while no changes were detected at 0 h among the 3 groups. These lipid changes largely reflected the difference between the nicotinamide supplemented groups and the water control group. Together with our previous results, this study shows that oral supplementation of nicotinamide within the daily tolerable upper level is an effective way to transiently increase NAD+ levels and affect the composition of blood lipids.
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- 2021
56. An approximation theory for strongly stabilizing solutions to the operator LQ Riccati equation.
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Job C. Oostveen, Ruth F. Curtain, and K. Ito
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- 2001
- Full Text
- View/download PDF
57. Temporal Profiles of Symptom Scores after Palliative Radiotherapy for Bleeding Gastric Cancer with the Adjustment for the Palliative Prognostic Index: An Exploratory Analysis of a Multicenter Prospective Observational Study (JROSG 17-3)
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T. Kawamoto, T. Saito, T. Kosugi, N. Nakamura, H. Wada, A. Tonari, H. Ogawa, N. Mitsuhashi, K. Yamada, T. Takahashi, K. Ito, S. Sekii, N. Araki, M. Nozaki, J. Heianna, K. Murotani, Y. Hirano, A. Satoh, T. Onoe, and N. Shikama
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Cancer Research ,Radiation ,Oncology ,Radiology, Nuclear Medicine and imaging - Published
- 2022
58. Stereotactic Body Radiotherapy vs. Conventional Radiotherapy for Painful Bone Metastases: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
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K. Ito, T. Saito, N. Nakamura, N. Imano, and P. Hoskin
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Cancer Research ,Radiation ,Oncology ,Radiology, Nuclear Medicine and imaging - Published
- 2022
59. 679P Clinical outcomes in patients with recurrent or metastatic head and neck squamous cell carcinoma after failure of platinum and nivolumab: A multicenter retrospective study
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H. Oka, K. Nagashima, H. Nishi, Y. Kumai, H. Iijima, K. Okami, Y. Shimizu, S. Kano, K. Ito, T. Yamazaki, H. Takahashi, N. Oridate, T. Yokota, T. Koyama, N. Kiyota, K. Kato, S. Kadowaki, and Y. Honma
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Oncology ,Hematology - Published
- 2022
60. 990P Osimertinib for RT-naïve CNS metastasis of EGFR mutation-positive NSCLC: Phase II OCEAN study (LOGIK 1603/WJOG 9116L), part of the first-line cohort
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H. Yamaguchi, K. Wakuda, M. Fukuda, H. Kenmotsu, K. Ito, Y. Tsuchiya-Kawano, K. Tanaka, T. Harada, Y. Nakatani, S. Miura, T. Yokoyama, T. Nakamura, M. Izumi, A. Nakamura, S. Ikeda, K. Takayama, K. Yoshimura, K. Nakagawa, N. Yamamoto, and K. Sugio
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Oncology ,Hematology - Published
- 2022
61. Model-based Cross-correlation Search for Gravitational Waves from the Low-mass X-Ray Binary Scorpius X-1 in LIGO O3 Data
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Abbott, R, Abe, H, Acernese, F, Ackley, K, Adhicary, S, Adhikari, N, Adhikari, R, Adkins, V, Adya, V, Affeldt, C, Agarwal, D, Agathos, M, Aguiar, O, Aiello, L, Ain, A, Ajith, P, Akutsu, T, Albanesi, S, Alfaidi, R, Alléné, C, Allocca, A, Altin, P, Amato, A, Anand, S, Ananyeva, A, Anderson, S, Anderson, W, Ando, M, Andrade, T, Andres, N, Andrés-Carcasona, M, Andrić, T, Ansoldi, S, Antelis, J, Antier, S, Apostolatos, T, Appavuravther, E, Appert, S, Apple, S, Arai, K, Araya, A, Araya, M, Areeda, J, Arène, M, Aritomi, N, Arnaud, N, Arogeti, M, Aronson, S, Asada, H, Ashton, G, Aso, Y, Assiduo, M, Assis de Souza Melo, S, Aston, S, Astone, P, Aubin, F, Aultoneal, K, Babak, S, Badaracco, F, Badger, C, Bae, S, Bae, Y, Bagnasco, S, Bai, Y, Baier, J, Baird, J, Bajpai, R, Baka, T, Ball, M, Ballardin, G, Ballmer, S, Baltus, G, Banagiri, S, Banerjee, B, Bankar, D, Barayoga, J, Barish, B, Barker, D, Barneo, P, Barone, F, Barr, B, Barsotti, L, Barsuglia, M, Barta, D, Bartlett, J, Barton, M, Bartos, I, Basak, S, Bassiri, R, Basti, A, Bawaj, M, Bayley, J, Bazzan, M, Bécsy, B, Bedakihale, V, Beirnaert, F, Bejger, M, Belahcene, I, Bell, A, Benedetto, V, Beniwal, D, Benoit, W, Bentley, J, Benyaala, M, Bera, S, Berbel, M, Bergamin, F, Berger, B, Bernuzzi, S, Beroiz, M, Bersanetti, D, Bertolini, A, Betzwieser, J, Beveridge, D, Bhandare, R, Bhandari, A, Bhardwaj, U, Bhatt, R, Bhattacharjee, D, Bhaumik, S, Bianchi, A, Bilenko, I, Bilicki, M, Billingsley, G, Bini, S, Birnholtz, O, Biscans, S, Bischi, M, Biscoveanu, S, Bisht, A, Biswas, B, Bitossi, M, Bizouard, M, Blackburn, J, Blair, C, Blair, D, Blair, R, Bobba, F, Bode, N, Boër, M, Bogaert, G, Boldrini, M, Bolingbroke, G, Bonavena, L, Bondarescu, R, Bondu, F, Bonilla, E, Bonnand, R, Booker, P, Bork, R, Boschi, V, Bose, N, Bose, S, Bossilkov, V, Boudart, V, Bouffanais, Y, Bozzi, A, Bradaschia, C, Brady, P, Bramley, A, Branch, A, Branchesi, M, Brau, J, Breschi, M, Briant, T, Briggs, J, Brillet, A, Brinkmann, M, Brockill, P, Brooks, A, Brooks, J, Brown, D, Brunett, S, Bruno, G, Bruntz, R, Bryant, J, Bucci, F, Buchanan, J, Bulik, T, Bulten, H, Buonanno, A, Burtnyk, K, Buscicchio, R, Buskulic, D, Buy, C, Byer, R, Cabourn Davies, G, Cabras, G, Cabrita, R, Cadonati, L, Cagnoli, G, Cahillane, C, Calderón Bustillo, J, Callaghan, J, Callister, T, Calloni, E, Camp, J, Canepa, M, Caneva, G, Cannavacciuolo, M, Cannon, K, Cao, H, Cao, Z, Capistran, L, Capocasa, E, Capote, E, Carapella, G, Carbognani, F, Carlassara, M, Carlin, J, Carpinelli, M, Carrillo, G, Carter, J, Carullo, G, Casanueva Diaz, J, Casentini, C, Castaldi, G, Caudill, S, Cavaglià, M, Cavalier, F, Cavalieri, R, Cella, G, Cerdá-Durán, P, Cesarini, E, Chaibi, W, Chakalis, W, Chalathadka Subrahmanya, S, Champion, E, Chan, C, Chan, K, Chan, M, Chandra, K, Chang, I, Chang, W, Chanial, P, Chao, S, Chapman-Bird, C, Charlton, P, Chassande-Mottin, E, Chatterjee, C, Chatterjee, D, Chaturvedi, M, Chaty, S, Chen, C, Chen, D, Chen, H, Chen, J, Chen, K, Chen, X, Chen, Y, Cheng, H, Chessa, P, Cheung, H, Chia, H, Chiadini, F, Chiang, C, Chiarini, G, Chierici, R, Chincarini, A, Chiofalo, M, Chiummo, A, Choudhary, R, Choudhary, S, Christensen, N, Chu, Q, Chu, Y, Chua, S, Chung, K, Ciani, G, Ciecielag, P, Cieślar, M, Cifaldi, M, Ciobanu, A, Ciolfi, R, Clara, F, Clark, J, Clarke, T, Clearwater, P, Clesse, S, Cleva, F, Coccia, E, Codazzo, E, Cohadon, P, Cohen, D, Colleoni, M, Collette, C, Colombo, A, Colpi, M, Compton, C, Conti, L, Cooper, S, Corban, P, Corbitt, T, Cordero-Carrión, I, Corezzi, S, Cornish, N, Corsi, A, Cortese, S, Coschizza, A, Cotesta, R, Cottingham, R, Coughlin, M, Coulon, J, Countryman, S, Cousins, B, Couvares, P, Coward, D, Cowart, M, Coyne, D, Coyne, R, Craig, K, Creighton, J, Creighton, T, Criswell, A, Croquette, M, Crowder, S, Cudell, J, Cullen, T, Cumming, A, Cummings, R, Cuoco, E, Curyło, M, Dabadie, P, Dal Canton, T, Dall'Osso, S, Dálya, G, Dana, A, D'Angelo, B, Danilishin, S, D'Antonio, S, Danzmann, K, Darsow-Fromm, C, Dasgupta, A, Datrier, L, Datta, S, Dattilo, V, Dave, I, Davier, M, Davis, D, Davis, M, Daw, E, Dax, M, Debra, D, Deenadayalan, M, Degallaix, J, De Laurentis, M, Deléglise, S, Del Favero, V, De Lillo, F, De Lillo, N, Dell'Aquila, D, Del Pozzo, W, De Matteis, F, D'Emilio, V, Demos, N, Dent, T, Depasse, A, De Pietri, R, De Rosa, R, De Rossi, C, Desalvo, R, De Simone, R, Dhurandhar, S, Diab, R, Díaz, M, Didio, N, Dietrich, T, Di Fiore, L, Di Fronzo, C, Di Giorgio, C, Di Giovanni, F, Di Giovanni, M, Di Girolamo, T, Diksha, D, Di Lieto, A, Di Michele, A, Di Pace, S, Di Palma, I, Di Renzo, F, Divakarla, A, Dmitriev, A, Doctor, Z, Doleva, P, Donahue, L, D'Onofrio, L, Donovan, F, Dooley, K, Dooney, T, Doravari, S, Dorosh, O, Drago, M, Driggers, J, Drori, Y, Ducoin, J, Dunn, L, Dupletsa, U, Durante, O, D'Urso, D, Duverne, P, Dwyer, S, Eassa, C, Easter, P, Ebersold, M, Eckhardt, T, Eddolls, G, Edelman, B, Edo, T, Edy, O, Effler, A, Eguchi, S, Eichholz, J, Eikenberry, S, Eisenmann, M, Eisenstein, R, Ejlli, A, Engelby, E, Enomoto, Y, Errico, L, Essick, R, Estellés, H, Estevez, D, Etzel, T, Evans, M, Evans, T, Evstafyeva, T, Ewing, B, Fabrizi, F, Faedi, F, Fafone, V, Fair, H, Fairhurst, S, Fan, P, Farah, A, Farr, B, Farr, W, Favaro, G, Favata, M, Fays, M, Fazio, M, Feicht, J, Fejer, M, Fenyvesi, E, Ferguson, D, Fernandez-Galiana, A, Ferrante, I, Ferreira, T, Fidecaro, F, Figura, P, Fiori, A, Fiori, I, Fishbach, M, Fisher, R, Fittipaldi, R, Fiumara, V, Flaminio, R, Floden, E, Fong, H, Font, J, Fornal, B, Forsyth, P, Franke, A, Frasca, S, Frasconi, F, Freed, J, Frei, Z, Freise, A, Freitas, O, Frey, R, Fritschel, P, Frolov, V, Fronzé, G, Fujii, Y, Fujikawa, Y, Fujimoto, Y, Fulda, P, Fyffe, M, Gabbard, H, Gabella, W, Gadre, B, Gair, J, Gais, J, Galaudage, S, Gamba, R, Ganapathy, D, Ganguly, A, Gao, D, Gaonkar, S, Garaventa, B, García-Núñez, C, García-Quirós, C, Gardner, K, Gargiulo, J, Garufi, F, Gasbarra, C, Gateley, B, Gayathri, V, Ge, G, Gemme, G, Gennai, A, George, J, Gerberding, O, Gergely, L, Ghonge, S, Ghosh, A, Ghosh, S, Ghosh, T, Giacoppo, L, Giaime, J, Giardina, K, Gibson, D, Gier, C, Giri, P, Gissi, F, Gkaitatzis, S, Glanzer, J, Gleckl, A, Godoy, F, Godwin, P, Goetz, E, Goetz, R, Golomb, J, Goncharov, B, González, G, Gosselin, M, Gouaty, R, Gould, D, Goyal, S, Grace, B, Grado, A, Graham, V, Granata, M, Granata, V, Gras, S, Grassia, P, Gray, C, Gray, R, Greco, G, Green, A, Green, R, Gretarsson, A, Gretarsson, E, Griffith, D, Griffiths, W, Griggs, H, Grignani, G, Grimaldi, A, Grimm, S, Grote, H, Grunewald, S, Gruson, A, Guerra, D, Guidi, G, Guimaraes, A, Gulati, H, Gulminelli, F, Gunny, A, Guo, H, Guo, Y, Gupta, A, Gupta, P, Gupta, S, Gurs, J, Gustafson, R, Gutierrez, N, Guzman, F, Ha, S, Hadiputrawan, I, Haegel, L, Haino, S, Halim, O, Hall, E, Hamilton, E, Hammond, G, Han, W, Haney, M, Hanks, J, Hanna, C, Hannam, M, Hannuksela, O, Hansen, H, Hanson, J, Harada, R, Harder, T, Haris, K, Harms, J, Harry, G, Harry, I, Hartwig, D, Hasegawa, K, Haskell, B, Haster, C, Hathaway, J, Hattori, K, Haughian, K, Hayakawa, H, Hayama, K, Hayes, F, Healy, J, Heidmann, A, Heidt, A, Heintze, M, Heinze, J, Heinzel, J, Heitmann, H, Hellman, F, Hello, P, Helmling-Cornell, A, Hemming, G, Hendry, M, Heng, I, Hennes, E, Hennig, J, Hennig, M, Henshaw, C, Hernandez, A, Hernandez Vivanco, F, Heurs, M, Hewitt, A, Higginbotham, S, Hild, S, Hill, P, Himemoto, Y, Hines, A, Hirata, N, Hirose, C, Ho, T, Hochheim, S, Hofman, D, Hohmann, J, Holcomb, D, Holland, N, Hollows, I, Holmes, Z, Holt, K, Holz, D, Hong, Q, Hough, J, Hourihane, S, Howell, D, Howell, E, Hoy, C, Hoyland, D, Hreibi, A, Hsieh, B, Hsieh, H, Hsiung, C, Huang, H, Huang, P, Huang, Y, Hübner, M, Huddart, A, Hughey, B, Hui, D, Hui, V, Husa, S, Huttner, S, Huxford, R, Huynh-Dinh, T, Hyland, J, Iandolo, G, Ide, S, Idzkowski, B, Iess, A, Inayoshi, K, Inoue, Y, Iosif, P, Irwin, J, Gupta, I, Isi, M, Ito, K, Itoh, Y, Iyer, B, Jaberianhamedan, V, Jacqmin, T, Jacquet, P, Jadhav, S, Jain, T, James, A, Jan, A, Jani, K, Janquart, J, Janssens, K, Janthalur, N, Jaranowski, P, Jariwala, D, Jarov, S, Jaume, R, Jenkins, A, Jenner, K, Jeon, C, Jia, W, Jiang, J, Jin, H, Johns, G, Johnston, R, Johny, N, Jones, A, Jones, D, Jones, P, Jones, R, Joshi, P, Ju, L, Jung, K, Jung, P, Junker, J, Juste, V, Kaihotsu, K, Kajita, T, Kakizaki, M, Kalaghatgi, C, Kalogera, V, Kamai, B, Kamiizumi, M, Kanda, N, Kandhasamy, S, Kang, G, Kanner, J, Kao, Y, Kapadia, S, Kapasi, D, Karat, S, Karathanasis, C, Karki, S, Kashyap, R, Kasprzack, M, Kastaun, W, Kato, T, Katsanevas, S, Katsavounidis, E, Katzman, W, Kaur, T, Kawabe, K, Kawaguchi, K, Kéfélian, F, Keitel, D, Key, J, Khadka, S, Khalili, F, Khan, S, Khanam, T, Khazanov, E, Khetan, N, Khursheed, M, Kijbunchoo, N, Kim, C, Kim, J, Kim, K, Kim, P, Kim, W, Kim, Y, Kimball, C, Kimura, N, King, B, Kinley-Hanlon, M, Kirchhoff, R, Kissel, J, Klimenko, S, Klinger, T, Knee, A, Knust, N, Kobayashi, Y, Koch, P, Koehlenbeck, S, Koekoek, G, Kohri, K, Kokeyama, K, Koley, S, Kolitsidou, P, Kolstein, M, Kondrashov, V, Kong, A, Kontos, A, Korobko, M, Kossak, R, Kovalam, M, Koyama, N, Kozak, D, Kozakai, C, Kranzhoff, L, Kringel, V, Krishnendu, N, Królak, A, Kuehn, G, Kuijer, P, Kulkarni, S, Kumar, A, Kumar, P, Kumar, R, Kume, J, Kuns, K, Kuromiya, Y, Kuroyanagi, S, Kuwahara, S, Kwak, K, Lacaille, G, Lagabbe, P, Laghi, D, Lalande, E, Lalleman, M, Lamberts, A, Landry, M, Lane, B, Lang, R, Lange, J, Lantz, B, La Rosa, I, Lartaux-Vollard, A, Lasky, P, Lawrence, J, Laxen, M, Lazzarini, A, Lazzaro, C, Leaci, P, Leavey, S, Lebohec, S, Lecoeuche, Y, Lee, E, Lee, H, Lee, K, Lee, R, Legred, I, Lehmann, J, Lemaître, A, Lenti, M, Leonardi, M, Leonova, E, Leroy, N, Letendre, N, Levesque, C, Levin, Y, Leviton, J, Leyde, K, Li, A, Li, B, Li, K, Li, P, Li, T, Li, X, Lin, C, Lin, E, Lin, F, Lin, H, Lin, L, Linde, F, Linker, S, Littenberg, T, Liu, G, Liu, J, Liu, X, Llamas, F, Lo, R, Lo, T, London, L, Longo, A, Lopez, D, Lopez Portilla, M, Lorenzini, M, Loriette, V, Lormand, M, Losurdo, G, Lott, T, Lough, J, Lousto, C, Lovelace, G, Lowry, M, Lucaccioni, J, Lück, H, Lumaca, D, Lundgren, A, Lung, Y, Luo, L, Lussier, A, Lynam, J, Ma'Arif, M, Macas, R, Macinnis, M, Macleod, D, Macmillan, I, Macquet, A, Magaña Hernandez, I, Magazzù, C, Magee, R, Maggiore, R, Magnozzi, M, Mahesh, S, Majorana, E, Makarem, C, Maksimovic, I, Maliakal, S, Malik, A, Man, N, Mandic, V, Mangano, V, Mannix, B, Mansell, G, Mansingh, G, Manske, M, Mantovani, M, Mapelli, M, Marchesoni, F, Marín Pina, D, Marion, F, Mark, Z, Márka, S, Márka, Z, Markakis, C, Markosyan, A, Markowitz, A, Maros, E, Marquina, A, Marsat, S, Martelli, F, Martin, I, Martin, R, Martinez, M, Martinez, V, Martinovic, K, Martynov, D, Marx, E, Masalehdan, H, Mason, K, Masserot, A, Masso-Reid, M, Mastrogiovanni, S, Matas, A, Mateu-Lucena, M, Matiushechkina, M, Mavalvala, N, Mccann, J, Mccarthy, R, Mcclelland, D, Mcclincy, P, Mccormick, S, Mcculler, L, Mcghee, G, Mcginn, J, Mcguire, S, Mcisaac, C, Mciver, J, Mcleod, A, Mcrae, T, Mcwilliams, S, Meacher, D, Mehmet, M, Mehta, A, Meijer, Q, Melatos, A, Mendell, G, Menendez-Vazquez, A, Menoni, C, Mercer, R, Mereni, L, Merfeld, K, Merilh, E, Merritt, J, Merzougui, M, Messenger, C, Messick, C, Meyers, P, Meylahn, F, Mhaske, A, Miani, A, Miao, H, Michaloliakos, I, Michel, C, Michimura, Y, Middleton, H, Mihaylov, D, Miller, A, Miller, B, Millhouse, M, Mills, J, Milotti, E, Minenkov, Y, Mio, N, Mir, L, Miravet-Tenés, M, Mishkin, A, Mishra, C, Mishra, T, Mistry, T, Mitchell, A, Mitra, S, Mitrofanov, V, Mitselmakher, G, Mittleman, R, Miyakawa, O, Miyo, K, Miyoki, S, Mo, G, Modafferi, L, Moguel, E, Mogushi, K, Mohapatra, S, Mohite, S, Molina-Ruiz, M, Mondal, C, Mondin, M, Montani, M, Moore, C, Moragues, J, Moraru, D, Morawski, F, More, A, More, S, Moreno, C, Moreno, G, Mori, Y, Morisaki, S, Morisue, N, Moriwaki, Y, Mours, B, Mow-Lowry, C, Mozzon, S, Muciaccia, F, Mukherjee, D, Mukherjee, S, Mukund, N, Mullavey, A, Munch, J, Muñiz, E, Murray, P, Muusse, S, Nadji, S, Nagano, K, Nagar, A, Nagar, T, Nakamura, K, Nakano, H, Nakano, M, Nakayama, Y, Napolano, V, Nardecchia, I, Narikawa, T, Narola, H, Naticchioni, L, Nayak, R, Neil, B, Neilson, J, Nelson, A, Nelson, T, Nery, M, Neubauer, P, Neunzert, A, Ng, K, Ng, S, Nguyen, C, Nguyen, P, Nguyen, T, Nguyen Quynh, L, Ni, J, Ni, W, Nichols, S, Nieradka, G, Nishimoto, T, Nishizawa, A, Nissanke, S, Nitoglia, E, Niu, W, Nocera, F, Norman, M, North, C, Notte, J, Novak, J, Nozaki, S, Nurbek, G, Nuttall, L, Obayashi, Y, Oberling, J, O'Brien, B, O'Dell, J, Oelker, E, Oertel, M, Ogaki, W, Oganesyan, G, Oh, J, Oh, K, Oh, S, O'Hanlon, T, Ohashi, M, Ohashi, T, Ohkawa, M, Ohme, F, Ohta, H, Okutani, Y, Oliveri, R, Olivetto, C, Oohara, K, Oram, R, O'Reilly, B, Ormiston, R, Ormsby, N, Orselli, M, O'Shaughnessy, R, O'Shea, E, Oshino, S, Ossokine, S, Osthelder, C, Otabe, S, Ottaway, D, Overmier, H, Pace, A, Pagano, G, Pagano, R, Pagliaroli, G, Pai, A, Pai, S, Pal, S, Palamos, J, Palashov, O, Palomba, C, Pan, K, Panda, P, Pang, P, Pannarale, F, 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Yamamoto, T. Yamamoto, K. Yamashita, R. Yamazaki, F. W. Yang, K. Z. Yang, L. Yang, Y. -C. Yang, Y. Yang, Yang Yang, M. J. Yap, D. W. Yeeles, S. -W. Yeh, A. B. Yelikar, J. Yokoyama, T. Yokozawa, J. Yoo, T. Yoshioka, Hang Yu, Haocun Yu, H. Yuzurihara, A. Zadrożny, M. Zanolin, S. Zeidler, T. Zelenova, J. -P. Zendri, M. Zevin, M. Zhan, H. Zhang, J. Zhang, L. Zhang, R. Zhang, T. Zhang, Y. Zhang, C. Zhao, G. Zhao, Y. Zhao, Yue Zhao, Y. Zheng, R. Zhou, X. J. Zhu, Z. -H. Zhu, A. B. Zimmerman, M. E. Zucker, and J. Zweizig
- Abstract
We present the results of a model-based search for continuous gravitational waves from the low-mass X-ray binary Scorpius X-1 using LIGO detector data from the third observing run of Advanced LIGO and Advanced Virgo. This is a semicoherent search that uses details of the signal model to coherently combine data separated by less than a specified coherence time, which can be adjusted to balance sensitivity with computing cost. The search covered a range of gravitational-wave frequencies from 25 to 1600 Hz, as well as ranges in orbital speed, frequency, and phase determined from observational constraints. No significant detection candidates were found, and upper limits were set as a function of frequency. The most stringent limits, between 100 and 200 Hz, correspond to an amplitude h(0) of about 10(-25) when marginalized isotropically over the unknown inclination angle of the neutron star's rotation axis, or less than 4 x 10(-26) assuming the optimal orientation. The sensitivity of this search is now probing amplitudes predicted by models of torque balance equilibrium. For the usual conservative model assuming accretion at the surface of the neutron star, our isotropically marginalized upper limits are close to the predicted amplitude from about 70 to 100 Hz; the limits assuming that the neutron star spin is aligned with the most likely orbital angular momentum are below the conservative torque balance predictions from 40 to 200 Hz. Assuming a broader range of accretion models, our direct limits on gravitational-wave amplitude delve into the relevant parameter space over a wide range of frequencies, to 500 Hz or more.
- Published
- 2022
62. Search for Gravitational Waves Associated with Gamma-Ray Bursts Detected by Fermi and Swift during the LIGO-Virgo Run O3b
- Author
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Sintes, V. Sipala, V. Skliris, B. J. J. Slagmolen, T. J. Slaven-Blair, J. Smetana, J. R. Smith, R. J. E. Smith, J. Soldateschi, S. N. Somala, K. Somiya, E. J. Son, K. Soni, S. Soni, V. Sordini, F. Sorrentino, N. Sorrentino, H. Sotani, R. Soulard, T. Souradeep, E. Sowell, V. Spagnuolo, A. P. Spencer, M. Spera, R. Srinivasan, A. K. Srivastava, V. Srivastava, K. Staats, C. Stachie, D. A. Steer, J. Steinlechner, S. Steinlechner, D. J. Stops, M. Stover, K. A. Strain, L. C. Strang, G. Stratta, A. Strunk, R. Sturani, A. L. Stuver, S. Sudhagar, V. Sudhir, R. Sugimoto, H. G. Suh, T. Z. Summerscales, H. Sun, L. Sun, S. Sunil, A. Sur, J. Suresh, P. J. Sutton, Takamasa Suzuki, Toshikazu Suzuki, B. L. Swinkels, M. J. Szczepa??czyk, P. Szewczyk, M. Tacca, H. Tagoshi, S. C. Tait, H. Takahashi, R. Takahashi, A. Takamori, S. Takano, H. Takeda, M. Takeda, C. J. Talbot, C. Talbot, H. Tanaka, Kazuyuki Tanaka, Kenta Tanaka, Taiki Tanaka, Takahiro Tanaka, A. J. Tanasijczuk, S. Tanioka, D. B. Tanner, D. Tao, L. Tao, E. N. Tapia San Martin, E. N. Tapia San Mart??n, C. Taranto, J. D. Tasson, S. Telada, R. Tenorio, J. E. Terhune, L. Terkowski, M. P. Thirugnanasambandam, M. Thomas, P. Thomas, E. E. Thompson, J. E. Thompson, S. R. Thondapu, K. A. Thorne, E. Thrane, Shubhanshu Tiwari, Srishti Tiwari, V. Tiwari, A. M. Toivonen, K. Toland, A. E. Tolley, T. Tomaru, Y. Tomigami, T. Tomura, M. Tonelli, A. Torres-Forn??, C. I. Torrie, I. Tosta e Melo, D. T??yr??, A. Trapananti, F. Travasso, G. Traylor, M. Trevor, M. C. Tringali, A. Tripathee, L. Troiano, A. Trovato, L. Trozzo, R. J. Trudeau, D. S. Tsai, D. Tsai, K. W. Tsang, T. Tsang, J-S. Tsao, M. Tse, R. Tso, K. Tsubono, S. Tsuchida, L. Tsukada, D. Tsuna, T. Tsutsui, T. Tsuzuki, K. Turbang, M. Turconi, D. Tuyenbayev, A. S. Ubhi, N. Uchikata, T. Uchiyama, R. P. Udall, A. Ueda, T. Uehara, K. Ueno, G. Ueshima, C. S. Unnikrishnan, F. Uraguchi, A. L. Urban, T. Ushiba, A. Utina, H. Vahlbruch, G. Vajente, A. Vajpeyi, G. Valdes, M. Valentini, V. Valsan, N. van Bakel, M. van Beuzekom, J. F. J. van den Brand, C. Van Den Broeck, D. C. Vander-Hyde, L. van der Schaaf, J. V. van Heijningen, J. Vanosky, M. H. P. M. van Putten, N. van Remortel, M. Vardaro, A. F. Vargas, V. Varma, M. Vas??th, A. Vecchio, G. Vedovato, J. Veitch, P. J. Veitch, J. Venneberg, G. Venugopalan, D. Verkindt, P. Verma, Y. Verma, D. Veske, F. Vetrano, A. Vicer??, S. Vidyant, A. D. Viets, A. Vijaykumar, V. Villa-Ortega, J. -Y. Vinet, A. Virtuoso, S. Vitale, T. Vo, H. Vocca, E. R. G. von Reis, J. S. A. von Wrangel, C. Vorvick, S. P. Vyatchanin, L. E. Wade, M. Wade, K. J. Wagner, R. C. Walet, M. Walker, G. S. Wallace, L. Wallace, S. Walsh, J. Wang, J. Z. Wang, W. H. Wang, R. L. Ward, J. Warner, M. Was, T. Washimi, N. Y. Washington, J. Watchi, B. Weaver, S. A. Webster, M. Weinert, A. J. Weinstein, R. Weiss, C. M. Weller, F. Wellmann, L. Wen, P. We??els, K. Wette, J. T. Whelan, D. D. White, B. F. Whiting, C. Whittle, D. Wilken, D. Williams, M. J. Williams, A. R. Williamson, J. L. Willis, B. Willke, D. J. Wilson, W. Winkler, C. C. Wipf, T. Wlodarczyk, G. Woan, J. Woehler, J. K. Wofford, I. C. F. Wong, C. Wu, D. S. Wu, H. Wu, S. Wu, D. M. Wysocki, L. Xiao, W-R. Xu, T. Yamada, H. Yamamoto, Kazuhiro Yamamoto, Kohei Yamamoto, T. Yamamoto, K. Yamashita, R. Yamazaki, F. W. Yang, L. Yang, Y. Yang, Yang Yang, Z. Yang, M. J. Yap, D. W. Yeeles, A. B. Yelikar, M. Ying, K. Yokogawa, J. Yokoyama, T. Yokozawa, J. Yoo, T. Yoshioka, Hang Yu, Haocun Yu, H. Yuzurihara, A. Zadro??ny, M. Zanolin, S. Zeidler, T. Zelenova, J. -P. Zendri, M. Zevin, M. Zhan, H. Zhang, J. Zhang, L. Zhang, T. Zhang, Y. Zhang, C. Zhao, G. Zhao, Y. Zhao, Yue Zhao, Y. Zheng, R. Zhou, Z. Zhou, X. J. Zhu, Z. -H. Zhu, A. B. Zimmerman, M. E. Zucker, and J. Zweizig
- Abstract
We search for gravitational-wave signals associated with gamma-ray bursts (GRBs) detected by the Fermi and Swift satellites during the second half of the third observing run of Advanced LIGO and Advanced Virgo (2019 November 1 15:00 UTC-2020 March 27 17:00 UTC). We conduct two independent searches: A generic gravitational-wave transients search to analyze 86 GRBs and an analysis to target binary mergers with at least one neutron star as short GRB progenitors for 17 events. We find no significant evidence for gravitational-wave signals associated with any of these GRBs. A weighted binomial test of the combined results finds no evidence for subthreshold gravitational-wave signals associated with this GRB ensemble either. We use several source types and signal morphologies during the searches, resulting in lower bounds on the estimated distance to each GRB. Finally, we constrain the population of low-luminosity short GRBs using results from the first to the third observing runs of Advanced LIGO and Advanced Virgo. The resulting population is in accordance with the local binary neutron star merger rate.
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- 2022
63. Weight loss, phase angle, and survival in cancer patients undergoing radiotherapy: a prospective study with 10-year follow-up
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Maria Cristina Gonzalez, Nathalia Pizato, Eduardo Yoshio Nakano, Marina K. Ito, and Elemárcia Martins da Silva Paixão
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Oncology ,medicine.medical_specialty ,medicine.medical_treatment ,Medicine (miscellaneous) ,Weight loss ,Neoplasms ,Internal medicine ,Weight Loss ,Electric Impedance ,Humans ,Medicine ,Prospective Studies ,Prospective cohort study ,Proportional Hazards Models ,Nutrition and Dietetics ,business.industry ,Proportional hazards model ,Cancer ,Anthropometry ,Prognosis ,medicine.disease ,Radiation therapy ,medicine.symptom ,business ,Bioelectrical impedance analysis ,Weight gain ,Follow-Up Studies - Abstract
Cancer patients undergoing radiotherapy (RT) frequently experience weight loss and changes in body composition, which negatively affect their nutritional status, lead to a poor clinical prognosis, and reduce survival rates. This study aimed to evaluate whether changes in body weight, phase angle, and standardized phase angle are associated with longer survival in cancer patients undergoing RT. This prospective cohort study included 62 cancer patients who underwent RT between 2008 and 2009 and were followed until 2019. Anthropometric and bioelectrical impedance analysis data were assessed before and after RT. The Kaplan–Meier method was used to calculate survival, and mortality risk was assessed using the Cox proportional hazards model. Kaplan–Meier analysis indicated no significant difference in survival time after the 10-year follow-up between patients who had weight loss during RT and those with weight maintenance or weight gain during RT. Mortality risk was associated, in the adjusted multivariate analysis, with age (p = 0.023), site of treatment (p = 0.001), and weight loss during RT (p = 0.044). Every 1 kg lost increased the risk of death by 25% compared with patients who maintained or gained weight during RT. Changes in phase angle and standardized phase angle after RT were not associated with increased mortality risk. Weight loss during RT, site of treatment, and age are associated with a higher risk of death in cancer patients after the 10-year follow-up.
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- 2020
64. Discordant responses of plasma low-density lipoprotein cholesterol and lipoprotein(a) to alirocumab: A pooled analysis from 10 ODYSSEY Phase 3 studies
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Matthew K. Ito, Sergio Fazio, Andrew Koren, Jessica Minnier, Michael D. Shapiro, Ivy W. Kam, Tahir Mahmood, and Qian H Li
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Male ,medicine.medical_specialty ,Epidemiology ,Low density lipoprotein cholesterol ,Familial hypercholesterolemia ,030204 cardiovascular system & hematology ,Antibodies, Monoclonal, Humanized ,03 medical and health sciences ,0302 clinical medicine ,Internal medicine ,medicine ,Humans ,030212 general & internal medicine ,Randomized Controlled Trials as Topic ,Alirocumab ,biology ,business.industry ,Anticholesteremic Agents ,PCSK9 ,PCSK9 Inhibitors ,Subtilisin ,Cholesterol, LDL ,Lipoprotein(a) ,Middle Aged ,medicine.disease ,Treatment Outcome ,Endocrinology ,Clinical Trials, Phase III as Topic ,biology.protein ,Kexin ,lipids (amino acids, peptides, and proteins) ,Proprotein Convertase 9 ,Cardiology and Cardiovascular Medicine ,business ,Lipoprotein - Abstract
AimsProprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors consistently reduce low-density lipoprotein cholesterol (LDL-C) by 50–60% and lipoprotein(a) (Lp(a)) by 20–30%, but the mechanism of Lp(a) lowering remains unclear. If Lp(a) is cleared by the LDL receptor, similar to LDL-C, then one would expect PCSK9 inhibition to induce a concordant LDL-C/Lp(a) response in an approximately 2:1 ratio. We aim to determine the prevalence of discordant plasma LDL-C/Lp(a) response to the PCSK9 inhibitor alirocumab.MethodsThis is a post hoc, pooled analysis of 10 randomized controlled trials from the ODYSSEY Phase 3 clinical trial program for alirocumab. Patients enrolled in the trials were high cardiovascular risk and/or with heterozygous familial hypercholesterolemia. The primary end point was prevalence of discordant LDL-C/Lp(a) response to alirocumab at 24 weeks. Discordant response was defined as LDL-C reduction >35% and Lp(a) reduction ≤10%, or LDL-C reduction ≤35% and Lp(a) reduction >10%.ResultsOf the 1709 patients in the pooled study cohort, 62.4% were male, and the mean age was 59.2 (SD: 11.0) years. Baseline mean LDL-C was 126.5 (SD: 46.3) mg/dL and baseline median Lp(a) was 46.9 (interquartile range: 21.8-89.0) mg/dL. Total prevalence of discordant LDL-C/Lp(a) response was 21.5% (12.6% with LDL-C >35% reduction and Lp(a) ≤10% reduction; 8.9% with LDL-C ≤35% reduction and Lp(a) >10% reduction). Baseline Lp(a) and familial hypercholesterolemia status did not affect discordance.ConclusionA high prevalence of discordant LDL-C/Lp(a) response was observed with alirocumab, further suggesting that PCSK9 inhibitor therapy with alirocumab reduces plasma Lp(a) through alternative pathways to LDL receptor clearance.
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- 2020
65. Waiawa Station (1934)
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Nakashima Naoto and Ken K. Ito
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General Earth and Planetary Sciences ,General Environmental Science - Published
- 2020
66. A nonrandomized study of single oral supplementation within the daily tolerable upper level of nicotinamide affects blood nicotinamide and NAD+ levels in healthy subjects
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Takuya Kitamoto, Yuki Onoda, Akio Hakamata, Shumpei Sato, Tomohito Sato, Yutaka Takahashi, Fumiyoshi Yamazaki, Mitsutoshi Setou, Masako Suzuki, Shinya Uchida, Makoto Horikawa, Keiichi Odagiri, and Takashi K. Ito
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0301 basic medicine ,Vitamin ,Aging ,medicine.medical_specialty ,Physiology ,lcsh:Medicine ,Nicotinamide adenine dinucleotide ,03 medical and health sciences ,chemistry.chemical_compound ,0302 clinical medicine ,Internal medicine ,NAD+ ,Medicine ,Potency ,Pharmacokinetics ,Nicotinamide ,Nicotinamide mononucleotide ,Whole blood ,business.industry ,lcsh:R ,Cell Biology ,Clinical trial ,030104 developmental biology ,Endocrinology ,chemistry ,Basal (medicine) ,Neurology (clinical) ,NAD+ kinase ,Geriatrics and Gerontology ,business ,030217 neurology & neurosurgery - Abstract
A decrease in nicotinamide adenine dinucleotide (NAD+) levels is a hallmark of aging in multiple organisms, including humans. We report a human clinical trial designed to assess the efficacy of single-dose supplementation of nicotinamide, a form of vitamin B3, on increasing NAD+ levels. Nicotinamide intake within the daily tolerable upper level (200 mg) led to the maximal whole blood concentration by a 30-fold increase at 0.5 h with a consistent decrease until 6 h in all 6 healthy male volunteers. The increase in blood nicotinamide amounted to 17%, whereas renal clearance accounted for 1.8% of the ingested dose. NAD+ levels reached a maximum concentration at 12 h, with all time points showing a trend of increase. Blood metabolome assay indicates that the metabolomic changes with NAM supplementation lasted 24 h and then returned to baseline by 48 h. The basal levels of whole blood NAD+ varied among individuals with a negative correlation with body height as well as nicotinamide mononucleotide (NMN) levels. These data warrant consideration for further clinical evaluation with repeated doses of nicotinamide within the safety dose range for the potency to increase NAD+ levels and potential accompanying benefits for healthy longevity.
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- 2020
67. Tunneling and countermeasure design in unexpected squeezing rock zone
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M. Yamazaki, T. Hironaka, K. Ito, and T. Kato
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- 2022
68. Global Properties of Sprites Observed over the Sea of Japan and the Pacific Ocean between 2016 and 2021
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M Duan, T Sakamoto, T Enoto, Y Wada, M Kamogawa, K Ito, T Miyoshi, T Sekiguchi, C Shimoda, and H Kawakami
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- 2022
69. Machine Learning-Based Gene Suggestion for Molecular Biology Experiments Using Diverse Information Sources
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Kei K. Ito, Yoshimasa Tsuruoka, and Daiju Kitagawa
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History ,Polymers and Plastics ,Business and International Management ,Industrial and Manufacturing Engineering - Published
- 2022
70. Measurements of the Schumann-Runge Bands of O2 with VUV-FT Spectrometer and Synchrotron Radiation Source
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K. Yoshino, J.R. Esmond, W.H. Parkinson, A.P. Thorne, L.E. Murray, G. Cox, R.C.M. Learner, K. Ito, T. Imajo, T. Mastsui, A. S.-C. Cheung, and K.-S. Leung
- Abstract
Current research on the Earth’s upper atmosphere requires molecular parameters of unprecedented detail and accuracy. State-of-the-art models of the vacuum-ultraviolet (VUV) absorbing properties of the atmosphere call for absorption cross sections with details on the scale of the Doppler linewidths (i.e., 0.1 to 0.15 cm−1 at 295 K). As a consequence, spectroscopic data at resolving powers of the order of 106 are needed. Current particular needs are for ultrahigh resolution absorption cross section data for some bands of NO and O2 in the UV to VUV region. To meet some of these requirements, we have used a UV Fourier transform (FT) spectrometer at Imperial College (IC) to measure the Herzberg I bands of O2 [1,2] and the δ (0,0) band of NO [3]
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- 2022
71. Neutron tagging following atmospheric neutrino events in a water Cherenkov detector
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K. Abe, Y. Haga, Y. Hayato, K. Hiraide, K. Ieki, M. Ikeda, S. Imaizumi, K. Iyogi, J. Kameda, Y. Kanemura, Y. Kataoka, Y. Kato, Y. Kishimoto, S. Miki, S. Mine, M. Miura, T. Mochizuki, S. Moriyama, Y. Nagao, M. Nakahata, T. Nakajima, Y. Nakano, S. Nakayama, T. Okada, K. Okamoto, A. Orii, K. Sato, H. Sekiya, M. Shiozawa, Y. Sonoda, Y. Suzuki, A. Takeda, Y. Takemoto, A. Takenaka, H. Tanaka, S. Tasaka, T. Tomura, K. Ueno, S. Watanabe, T. Yano, T. Yokozawa, S. Han, T. Irvine, T. Kajita, I. Kametani, K. Kaneyuki, K.P. Lee, T. McLachlan, K. Okumura, E. Richard, T. Tashiro, R. Wang, J. Xia, G.D. Megias, D. Bravo-Berguño, L. Labarga, B. Zaldivar, M. Goldhaber, F.d.M. Blaszczyk, J. Gustafson, C. Kachulis, E. Kearns, J.L. Raaf, J.L. Stone, L.R. Sulak, S. Sussman, L. Wan, T. Wester, B.W. Pointon, J. Bian, G. Carminati, M. Elnimr, N.J. Griskevich, W.R. Kropp, S. Locke, A. Renshaw, M.B. Smy, H.W. Sobel, V. Takhistov, P. Weatherly, K.S. Ganezer, B.L. Hartfiel, J. Hill, W.E. Keig, N. Hong, J.Y. Kim, I.T. Lim, R.G. Park, T. Akiri, B. Bodur, A. Himmel, Z. Li, E. O'Sullivan, K. Scholberg, C.W. Walter, T. Wongjirad, L. Bernard, A. Coffani, O. Drapier, S. El Hedri, A. Giampaolo, J. Imber, Th.A. Mueller, P. Paganini, B. Quilain, T. Ishizuka, T. Nakamura, J.S. Jang, K. Choi, J.G. Learned, S. Matsuno, S.N. Smith, J. Amey, L.H.V. Anthony, R.P. Litchfield, W.Y. Ma, D. Marin, A.A. Sztuc, Y. Uchida, M.O. Wascko, V. Berardi, M.G. Catanesi, R.A. Intonti, E. Radicioni, N.F. Calabria, G. De Rosa, L.N. Machado, G. Collazuol, F. Iacob, M. Lamoureux, N. Ospina, L. Ludovici, M. Gonin, G. Pronost, Y. Maekawa, Y. Nishimura, S. Cao, M. Friend, T. Hasegawa, T. Ishida, T. Ishii, M. Jakkapu, T. Kobayashi, T. Matsubara, T. Nakadaira, K. Nakamura, Y. Oyama, K. Sakashita, T. Sekiguchi, T. Tsukamoto, T. Boschi, F. Di Lodovico, J. Migenda, S. Molina Sedgwick, M. Taani, S. Zsoldos, K.E. Abe, M. Hasegawa, Y. Isobe, Y. Kotsar, H. Miyabe, H. Ozaki, T. Shiozawa, T. Sugimoto, A.T. Suzuki, Y. Takeuchi, S. Yamamoto, A. Ali, Y. Ashida, C. Bronner, J. Feng, T. Hayashino, T. Hiraki, S. Hirota, K. Huang, M. Jiang, T. Kikawa, M. Mori, A. Murakami, KE. Nakamura, T. Nakaya, N.D. Patel, K. Suzuki, S. Takahashi, K. Tateishi, R.A. Wendell, K. Yasutome, P. Fernandez, N. McCauley, P. Mehta, A. Pritchard, K.M. Tsui, Y. Fukuda, Y. Itow, H. Menjo, G. Mitsuka, M. Murase, F. Muto, T. Niwa, T. Suzuki, M. Tsukada, K. Frankiewicz, P. Mijakowski, J. Hignight, J. Jiang, C.K. Jung, X. Li, J.L. Palomino, G. Santucci, C. Vilela, M.J. Wilking, C. Yanagisawa, D. Fukuda, K. Hagiwara, M. Harada, T. Horai, H. Ishino, S. Ito, T. Kayano, A. Kibayashi, H. Kitagawa, Y. Koshio, W. Ma, T. Mori, H. Nagata, N. Piplani, S. Sakai, M. Sakuda, Y. Takahira, C. Xu, R. Yamaguchi, Y. Kuno, G. Barr, D. Barrow, L. Cook, A. Goldsack, S. Samani, C. Simpson, D. Wark, F. Nova, R. Tacik, J.Y. Yang, A. Cole, S.J. Jenkins, M. Malek, J.M. McElwee, O. Stone, M.D. Thiesse, L.F. Thompson, H. Okazawa, Y. Choi, S.B. Kim, I. Yu, A.K. Ichikawa, K. Ito, K. Nishijima, R.G. Calland, P. de Perio, K. Martens, M. Murdoch, M.R. Vagins, M. Koshiba, Y. Totsuka, K. Iwamoto, Y. Nakajima, N. Ogawa, Y. Suda, M. Yokoyama, D. Hamabe, S. Izumiyama, M. Kuze, Y. Okajima, M. Tanaka, T. Yoshida, M. Inomoto, M. Ishitsuka, H. Ito, R. Matsumoto, K. Ohta, M. Shinoki, J.F. Martin, C.M. Nantais, H.A. Tanaka, T. Towstego, R. Akutsu, M. Hartz, A. Konaka, N.W. Prouse, S. Chen, B.D. Xu, Y. Zhang, S. Berkman, S. Tobayama, K. Connolly, R.J. Wilkes, M. Posiadala-Zezula, D. Hadley, B. Richards, B. Jamieson, J. Walker, Ll. Marti, A. Minamino, G. Pintaudi, S. Sano, R. Sasaki, Abe, K., Haga, Y., Hayato, Y., Hiraide, K., Ieki, K., Ikeda, M., Imaizumi, S., Iyogi, K., Kameda, J., Kanemura, Y., Kataoka, Y., Kato, Y., Kishimoto, Y., Miki, S., Mine, S., Miura, M., Mochizuki, T., Moriyama, S., Nagao, Y., Nakahata, M., Nakajima, T., Nakano, Y., Nakayama, S., Okada, T., Okamoto, K., Orii, A., Sato, K., Sekiya, H., Shiozawa, M., Sonoda, Y., Suzuki, Y., Takeda, A., Takemoto, Y., Takenaka, A., Tanaka, H., Tasaka, S., Tomura, T., Ueno, K., Watanabe, S., Yano, T., Yokozawa, T., Han, S., Irvine, T., Kajita, T., Kametani, I., Kaneyuki, K., Lee, K. P., Mclachlan, T., Okumura, K., Richard, E., Tashiro, T., Wang, R., Xia, J., Megias, G. D., Bravo-Bergu??o, D., Labarga, L., Zaldivar, B., Goldhaber, M., Blaszczyk, F. d. M., Gustafson, J., Kachulis, C., Kearns, E., Raaf, J. L., Stone, J. L., Sulak, L. R., Sussman, S., Wan, L., Wester, T., Pointon, B. W., Bian, J., Carminati, G., Elnimr, M., Griskevich, N. J., Kropp, W. R., Locke, S., Renshaw, A., Smy, M. B., Sobel, H. W., Takhistov, V., Weatherly, P., Ganezer, K. S., Hartfiel, B. L., Hill, J., Keig, W. E., Hong, N., Kim, J. Y., Lim, I. T., Park, R. G., Akiri, T., Bodur, B., Himmel, A., Li, Z., O'Sullivan, E., Scholberg, K., Walter, C. W., Wongjirad, T., Bernard, L., Coffani, A., Drapier, O., El Hedri, S., Giampaolo, A., Imber, J., Mueller, Th. A., Paganini, P., Quilain, B., Ishizuka, T., Nakamura, T., Jang, J. S., Choi, K., Learned, J. G., Matsuno, S., Smith, S. N., Amey, J., Anthony, L. H. V., Litchfield, R. P., Ma, W. Y., Marin, D., Sztuc, A. A., Uchida, Y., Wascko, M. O., Berardi, V., Catanesi, M. G., Intonti, R. A., Radicioni, E., Calabria, N. F., De Rosa, G., Nascimento Machado, L., Collazuol, G., Iacob, F., Lamoureux, M., Ospina, N., Ludovici, L., Gonin, M., Pronost, G., Maekawa, Y., Nishimura, Y., Cao, S., Friend, M., Hasegawa, T., Ishida, T., Ishii, T., Jakkapu, M., Kobayashi, T., Matsubara, T., Nakadaira, T., Nakamura, K., Oyama, Y., Sakashita, K., Sekiguchi, T., Tsukamoto, T., Boschi, T., Di Lodovico, F., Migenda, J., Molina Sedgwick, S., Taani, M., Zsoldos, S., Abe, K. E., Hasegawa, M., Isobe, Y., Kotsar, Y., Miyabe, H., Ozaki, H., Shiozawa, T., Sugimoto, T., Suzuki, A. T., Takeuchi, Y., Yamamoto, S., Ali, A., Ashida, Y., Bronner, C., Feng, J., Hayashino, T., Hiraki, T., Hirota, S., Huang, K., Jiang, M., Kikawa, T., Mori, M., Murakami, A., Nakamura, Ke., Nakaya, T., Patel, N. D., Suzuki, K., Takahashi, S., Tateishi, K., Wendell, R. A., Yasutome, K., Fernandez, P., Mccauley, N., Mehta, P., Pritchard, A., Tsui, K. M., Fukuda, Y., Itow, Y., Menjo, H., Mitsuka, G., Murase, M., Muto, F., Niwa, T., Suzuki, T., Tsukada, M., Frankiewicz, K., Mijakowski, P., Hignight, J., Jiang, J., Jung, C. K., Li, X., Palomino, J. L., Santucci, G., Vilela, C., Wilking, M. J., Yanagisawa, C., Fukuda, D., Hagiwara, K., Harada, M., Horai, T., Ishino, H., Ito, S., Kayano, T., Kibayashi, A., Kitagawa, H., Koshio, Y., Ma, W., Mori, T., Nagata, H., Piplani, N., Sakai, S., Sakuda, M., Takahira, Y., Xu, C., Yamaguchi, R., Kuno, Y., Barr, G., Barrow, D., Cook, L., Goldsack, A., Samani, S., Simpson, C., Wark, D., Nova, F., Tacik, R., Yang, J. Y., Cole, A., Jenkins, S. J., Malek, M., Mcelwee, J. M., Stone, O., Thiesse, M. D., Thompson, L. F., Okazawa, H., Choi, Y., Kim, S. B., Yu, I., Ichikawa, A. K., Ito, K., Nishijima, K., Calland, R. G., de Perio, P., Martens, K., Murdoch, M., Vagins, M. R., Koshiba, M., Totsuka, Y., Iwamoto, K., Nakajima, Y., Ogawa, N., Suda, Y., Yokoyama, M., Hamabe, D., Izumiyama, S., Kuze, M., Okajima, Y., Tanaka, M., Yoshida, T., Inomoto, M., Ishitsuka, M., Ito, H., Matsumoto, R., Ohta, K., Shinoki, M., Martin, J. F., Nantais, C. M., Tanaka, H. A., Towstego, T., Akutsu, R., Hartz, M., Konaka, A., Prouse, N. W., Chen, S., Xu, B. D., Zhang, Y., Berkman, S., Tobayama, S., Connolly, K., Wilkes, R. J., Posiadala-Zezula, M., Hadley, D., Richards, B., Jamieson, B., Walker, J., Marti, Ll., Minamino, A., Pintaudi, G., Sano, S., and Sasaki, R.
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Physics - Instrumentation and Detectors ,Large detector systems for particle and astroparticle physics ,hep-ex ,Cherenkov detectors ,FOS: Physical sciences ,Acceleratorfysik och instrumentering ,Instrumentation and Detectors (physics.ins-det) ,Accelerator Physics and Instrumentation ,High Energy Physics - Experiment ,Subatomär fysik ,High Energy Physics - Experiment (hep-ex) ,Particle identification methods ,Neutrino detectors ,Subatomic Physics ,Cherenkov detectors Large detector systems for particle and astroparticle physics Neutrino detectors Particle identification methods ,Detectors and Experimental Techniques ,Astrophysics - Instrumentation and Methods for Astrophysics ,Instrumentation ,Instrumentation and Methods for Astrophysics (astro-ph.IM) ,physics.ins-det ,Mathematical Physics ,Particle Physics - Experiment ,astro-ph.IM - Abstract
We present the development of neutron-tagging techniques in Super-Kamiokande IV using a neural network analysis. The detection efficiency of neutron capture on hydrogen is estimated to be 26%, with a mis-tag rate of 0.016 per neutrino event. The uncertainty of the tagging efficiency is estimated to be 9.0%. Measurement of the tagging efficiency with data from an Americium-Beryllium calibration agrees with this value within 10%. The tagging procedure was performed on 3,244.4 days of SK-IV atmospheric neutrino data, identifying 18,091 neutrons in 26,473 neutrino events. The fitted neutron capture lifetime was measured as 218±9 μs. We present the development of neutron-tagging techniques in Super-Kamiokande IV using a neural network analysis. The detection efficiency of neutron capture on hydrogen is estimated to be 26%, with a mis-tag rate of 0.016 per neutrino event. The uncertainty of the tagging efficiency is estimated to be 9.0%. Measurement of the tagging efficiency with data from an Americium-Beryllium calibration agrees with this value within 10%. The tagging procedure was performed on 3,244.4 days of SK-IV atmospheric neutrino data, identifying 18,091 neutrons in 26,473 neutrino events. The fitted neutron capture lifetime was measured as 218 \pm 9 \mu s.
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- 2022
72. LEXAS: a web application for life science experiment search and suggestion
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Kei K Ito, Yoshimasa Tsuruoka, and Daiju Kitagawa
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MotivationIn cellular biology, researchers design wet experiments by reading the relevant articles and considering the described experiments and results. Today, researchers spend a long time exploring the literature in order to plan experiments.ResultsTo accelerate experiment planning, we have developed a web application named LEXAS (Life-science EXperiment seArch and Suggestion). LEXAS curates the description of biomedical experiments and suggests the experiments on genes that could be performed next. To develop LEXAS, we first retrieved the descriptions of experiments from full-text biomedical articles archived in PubMed Central. Using these retrieved experiments and biomedical knowledgebases and databases, we trained a machine learning model that suggests the next experiments. This model can suggest not only reasonable genes but also novel genes as targets for the next experiment as long as they share some critical features with the gene of interest.Availability and implementationLEXAS is available at https://lexas.f.u-tokyo.ac.jp/ and provides users with two interfaces: search and suggestion. The search interface allows users to find a comprehensive list of experiment descriptions, and the suggestion interface allows users to find a list of genes that could be analyzed along with possible experiment methods. The source code is available at https://github.com/lexas-f-utokyo/lexas.Contactito-delightfully-kei@g.ecc.u-tokyo.ac.jpSupplementary informationSupplementary data are available at Bioinformatics online.
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- 2021
73. Aortic Valve and Arch Replacements in a High-Risk Patient with Essential Thrombocythemia
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H, Harada, primary, H, Miyamoto, additional, T, Nakastu, additional, F, Kimura, additional, T, Baba, additional, and K, Ito, additional
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- 2022
- Full Text
- View/download PDF
74. Pain Response Rates after Conventional Radiation Therapy for Bone Metastases Assessed Using International Consensus Pain Response Endpoints: A Systematic Review and Meta-Analysis of Initial Radiation Therapy and Re-Irradiation
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N. Imano, T. Saito, N. Nakamura, K. Ito, A. Yorozu, I. Nishibuchi, Y. Murakami, and Y. Nagata
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Cancer Research ,Radiation ,Oncology ,Radiology, Nuclear Medicine and imaging - Published
- 2022
75. 333P Efficacy and safety of immune checkpoint inhibitors alone or combined with chemotherapy in pulmonary sarcomatoid carcinoma
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H. Kaneda, D. Hazama, H. Kodama, A. Miyazaki, K. Azuma, Y. Kawashima, Y. Sato, K. Ito, Y. Shiraishi, K. Miura, T. Takahama, S. Oizumi, Y. Namba, S. Ikeda, S. Miura, and M. Tachihara
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Oncology ,Hematology - Published
- 2022
76. 52P HGCSG1901: A retrospective cohort study evaluating the safety and efficacy of S-1 and irinotecan plus bevacizumab in patients with metastatic colorectal cancer - Impact of single-heterozygous UGT1A1 on the clinical outcomes
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S. Yuki, K. Ito, K. Harada, Y. Kawamoto, M. Yagisawa, K. Sawada, A. Ishiguro, O. Muto, K. Hatanaka, H. Okuda, A. Sato, Y. Sasaki, M. Nakamura, T. Meguro, M. Dazai, H. Nakatsumi, A. Ueda, N. Sakamoto, Y. Sakata, and Y. Komatsu
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Oncology ,Hematology - Published
- 2022
77. Multi-Institutional Prospective Observational Study of Radiotherapy for Metastatic Bone Tumor
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H. Harada, N. Shikama, A. Notsu, H. Shirato, K. Yamada, H. Uezono, Y. Koide, H. Kubota, T. Yamazaki, K. Ito, J. Heianna, Y. Okada, A. Tonari, N. Katoh, H. Wada, Y. Ejima, K. Yoshida, T. Kosugi, S. Takahashi, T. Komiyama, N. Uchida, M. Miwa, M. Watanabe Nemoto, H. Nagakura, H. Ikeda, T. Saito, I. Asakawa, T. Takahashi, and N. Shigematsu
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Cancer Research ,Radiation ,Oncology ,Radiology, Nuclear Medicine and imaging - Published
- 2022
78. 1535P Efficacy and safety of amrubicin after treatment with immune checkpoint inhibitor combined with chemotherapy in extensive-stage small cell carcinoma: MiSSION1
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T. Nishimura, H. Fujimoto, T. Fujiwara, K. Ito, A. Fujiwara, H. Yuda, H. Itani, C.N. D'Alessandro-Gabazza, E.C. Gabazza, and T. Kobayashi
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Oncology ,Hematology - Published
- 2022
79. Intelligent Design System of CIM for Shipbuilding.
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K. Koga, K. Ito, Y. Nakai, and J. Fujita
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- 1991
80. Effect of peripheral cryoneurotomy and nerve transection on the trigeminal ganglion in rats
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Alastair N. Goss, K. Ito, and R. D’Rozario
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business.industry ,Mandibular Nerve ,medicine.medical_treatment ,Neurectomy ,medicine.disease ,Mental nerve ,Rats ,Peripheral ,Trigeminal ganglion ,Trigeminal Ganglion ,Otorhinolaryngology ,Full recovery ,Trigeminal neuralgia ,Anesthesia ,medicine ,Animals ,Surgery ,Oral Surgery ,business - Abstract
In this experimental study, we did peripheral neurectomyand peripheral cryoneurotomy of the mental nerve in rats and histologically assessed their effects on the trigeminal ganglion at timed intervals for six months. There were marked irreversible changes in the neurectomy group whereas the cryoneurotomy group made a full recovery. These results help to explain the differing effects of these procedures on trigeminal neuralgia.
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- 2019
81. The Cep57-pericentrin module organizes PCM expansion and centriole engagement
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Koki Watanabe, Daisuke Takao, Kei K. Ito, Daiju Kitagawa, and Mikiko Takahashi
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0301 basic medicine ,Microcephaly ,Centriole ,Science ,Mitosis ,General Physics and Astronomy ,02 engineering and technology ,Osteodysplastic primordial dwarfism ,Biology ,medicine.disease_cause ,Article ,General Biochemistry, Genetics and Molecular Biology ,Chromosome segregation ,03 medical and health sciences ,Protein Domains ,medicine ,Humans ,Antigens ,lcsh:Science ,Centrioles ,Pericentriolar material ,Centrosome ,Mutation ,Multidisciplinary ,Nuclear Proteins ,General Chemistry ,Cell cycle ,021001 nanoscience & nanotechnology ,medicine.disease ,Cell biology ,030104 developmental biology ,lcsh:Q ,0210 nano-technology ,Microtubule-Associated Proteins ,HeLa Cells ,Protein Binding - Abstract
Centriole duplication occurs once per cell cycle to ensure robust formation of bipolar spindles and chromosome segregation. Each newly-formed daughter centriole remains connected to its mother centriole until late mitosis. The disengagement of the centriole pair is required for centriole duplication. However, the mechanisms underlying centriole engagement remain poorly understood. Here, we show that Cep57 is required for pericentriolar material (PCM) organization that regulates centriole engagement. Depletion of Cep57 causes PCM disorganization and precocious centriole disengagement during mitosis. The disengaged daughter centrioles acquire ectopic microtubule-organizing-center activity, which results in chromosome mis-segregation. Similar defects are observed in mosaic variegated aneuploidy syndrome patient cells with cep57 mutations. We also find that Cep57 binds to the well-conserved PACT domain of pericentrin. Microcephaly osteodysplastic primordial dwarfism disease pericentrin mutations impair the Cep57-pericentrin interaction and lead to PCM disorganization. Together, our work demonstrates that Cep57 provides a critical interface between the centriole core and PCM., Centriole disengagement occurs towards mitotic exit and involves cleavage of pericentrin, a component of the pericentriolar material. Here the authors show that depletion of the centrosomal protein Cep57 leads to precocious centriole disengagement, and that Cep57 binds pericentrin.
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- 2019
82. Association between Subjective Evaluation of Skin Toxicities and Quality of Life in Patients with Lung Cancer Undergoing Epidermal Growth Factor Receptor-Tyrosine Kinase Inhibitor Treatment: A Pilot Study for Developing Skin Toxicity Assessment
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K. Ito, Megumi Chiba, Ya Su, Kengo Hirayama, Yasuyuki Ikezawa, and Michiko Yuki
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Oncology ,medicine.medical_specialty ,integumentary system ,030504 nursing ,biology ,business.industry ,Therapeutic effect ,Cancer ,medicine.disease ,Hospital Anxiety and Depression Scale ,Rash ,03 medical and health sciences ,0302 clinical medicine ,Quality of life ,Internal medicine ,Toxicity ,medicine ,biology.protein ,030212 general & internal medicine ,Epidermal growth factor receptor ,medicine.symptom ,0305 other medical science ,business ,Lung cancer - Abstract
Purposes: Epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitors (TKIs) exert satisfactory therapeutic effects in lung cancer patients. However, the resultant skin toxicity can deteriorate patients’ quality of life (QoL). Differences exist in skin toxicity evaluation between patients and clinicians. We aimed to clarify the association between the subjective evaluation of skin toxicities and QoL in lung cancer patients and to establish a document of scale development in the subjective evaluation of skin toxicity. Methods: We used self-administered questionnaires to evaluate 12 lung cancer patients receiving EGFR-TKI treatment. Indices of QoL were generated using the Functional Assessment of Cancer Therapy-Lung and Hospital Anxiety and Depression Scale, and a subjective evaluation questionnaire concerning skin toxicity was completed. The data were collected immediately before treatment initiation and at 4 weeks post treatment. Results: In the subjective evaluation of skin toxicity, four patients (33.3%) were classified as ≥Grade 2 (painful group), experiencing painful pruritus at the emergence site of the skin rash or xerosis. In this group, the QoL scores of physical and emotional aspects declined after treatment. Conversely, patients in the painless group (Grade 0 - 1) demonstrated an improved emotional QoL following treatment (p = 0.028). Conclusions: Lung cancer patients suffering from painful skin toxicity tended to show a decline in the physical and emotional aspects of QoL following EGFR-TKI treatment. The skin toxicity questionnaire was useful from the point of view of a subjective evaluation and could be a powerful assessment tool in future clinical settings with further modification.
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- 2019
83. SO-30 Impact of single-heterozygous UGT1A1 on the clinical outcomes of nano-liposomal irinotecan plus 5-fluorouracil/leucovorin for patients with pancreatic ductal adenocarcinoma
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K. Harada, T. Yamamura, O. Muto, M. Nakamura, S. Sogabe, K. Sawada, S. Nakano, M. Yagisawa, T. Muranaka, M. Dazai, M. Tateyama, K. Ito, R. Saito, Y. Kobayashi, S. Kato, T. Miyagishima, Y. Kawamoto, S. Yuki, Y. Sakata, N. Sakamoto, and Y. Komatsu
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Oncology ,Hematology - Published
- 2022
84. Overview of KAGRA: Calibration, detector characterization, physical environmental monitors, and the geophysics interferometer
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R. Shimizu, Ettore Majorana, H. B. Jin, P. Jung, M. Fukunaga, G-Z. Huang, F. E. Peña Arellano, H. Pang, Kunihiro Nagano, John J. Oh, Atsushi Nishizawa, M. Nakano, C. Kozakai, Yasufumi Kojima, S. Saito, Takayuki Tomaru, T. Tomura, Y. Fujikawa, Kazuhiro Hayama, Hajime Sotani, Shigeo Nagano, Masatake Ohashi, S. Otabe, Naoki Aritomi, Chunglee Kim, Tatsuhiro Yamada, Kipp Cannon, Shuen De Wu, Yuhang Zhao, Fumihiro Uraguchi, Hideki Asada, Ryutaro Takahashi, Kei Kotake, Yutaro Enomoto, Naoko Ohishi, L. W. Luo, K. Inayoshi, S. Bae, S. Ha, Sadakazu Haino, T. Narikawa, Yoshiyuki Obuchi, Ryo Yamazaki, K. Hattori, Y. Tomigami, K. Ueno, Zhoujian Cao, Keiko Kokeyama, Kentaro Somiya, G. Ge, K. Yamashita, Wei-Tou Ni, Satoshi Tsuchida, Takashi Sato, M. Zhan, Akiteru Takamori, Masaki Ando, Y. Nakayama, F. K. Lin, W-R. Xu, T. Sawada, Seog Oh, Ray-Kuang Lee, C. P. Ooi, C. Chen, Takahiro Tanaka, S. Ide, H. Vocca, J. Wang, Albert K. H. Kong, T. Yoshioka, Lijing Shao, T. Shimoda, Y. Okutani, R. Flaminio, S. Eguchi, T. Sekiguchi, Y. Sakuno, R. Kozu, Hyang Woon Lee, Zong-Hong Zhu, Y. Hiranuma, Wen-Biao Han, Hideaki Hayakawa, K. Chen, Y. Mori, Yuki Fujii, H. Ohta, Y. Miyazaki, A. Shoda, B. H. Hsieh, Y. Sakai, K. Sakai, S. Oshino, T. Ushiba, Luca Baiotti, Simon Zeidler, Yousuke Itoh, Hiroyuki Nakano, Takaaki Kajita, Yuki Inoue, S. Shibagaki, Hiroyuki Takeda, Chau Ron Wu, Y-K. Chu, M. Kamiizumi, Guo-Chin Liu, Yoshiaki Himemoto, I. M. Pinto, S. Sato, Y. Kuromiya, Yuta Michimura, N. Hirata, A. Miyamoto, Y. Huang, K. L. Li, Yi Chen, Yuichiro Sekiguchi, Kimio Tsubono, Hideyuki Tagoshi, S. Imam, H. L. Lin, M. Chan, Rajesh Kumar, L. C.C. Lin, K. Kusayanagi, K. Okutomi, D. C. Y. Hui, Sachiko Kuroyanagi, K. Kaihotsu, J. Kim, Jinsook Kim, K. Ito, Takashi Uchiyama, Kunihito Ioka, L. Nguyen Quynh, K. Yokogawa, R. Bajpai, K. Shimode, Norikatsu Mio, Koya Arai, Toshihiro Tsuzuki, L. Naticchioni, T. Shishido, R. Nakashima, M. Takeda, Akito Araya, A. Parisi, T. Yokozawa, E. N. Tapia San Martin, Souichi Telada, M. H. P. M. van Putten, Jishnu Suresh, Y. Arai, K. Miyo, K. Oohara, N. Kawai, Soichiro Morisaki, C. Jeon, W. S. Kim, T. Uehara, Jun'ichi Yokoyama, Nobutada Kimura, K. Oh, D. Tuyenbayev, Kentaro Komori, N. Kita, T. Kawasaki, T. Tsang, Hong Wu, Yi Yang, Kuo-Chuan Pan, S. Tanioka, K. Jung, A. Hagiwara, D. Gao, R. Negishi, C-Y. Lin, E. Capocasa, Shinji Miyoki, H. Chu, G. Ueshima, Tomotada Akutsu, M. A. Barton, Y. M. Kim, C-Y. Chiang, Hisa-aki Shinkai, L. Trozzo, Norichika Sago, K. Kwak, J. Kume, Takahiro Yamamoto, Nobuyuki Kanda, S. Nozaki, H. K. Tanaka, H. Yuzurihara, Masako Kakizaki, Eiichi Hirose, Kouji Nakamura, F-L. Lin, M. Leonardi, Haruki Kitazawa, J-S. Tsao, Takuya Tsutsui, M. Marchio, Yoichi Aso, J. Park, K. Izumi, F. Travasso, Hirotaka Takahashi, Nami Uchikata, Mitsuhiro Fukushima, H. Y. Huang, G. Kang, H. Zhang, A. Ueda, Sakae Araki, Osamu Miyakawa, Chin Guo Kuo, Y. Moriwaki, K. Yamamoto, Toshio Suzuki, Hyun Lee, Y. Bae, Masashi Ohkawa, K. Hasegawa, T. Washimi, Kyohei Kawaguchi, B. Ikenoue, H-S. Kuo, P. W. Huang, Kazuyuki Tanaka, Y. Saito, S. Takano, E. J. Son, W. Ogaki, Z. Hong, R. Sugimoto, Laboratoire d'Annecy de Physique des Particules (LAPP), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-Centre National de la Recherche Scientifique (CNRS), and KAGRA
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[PHYS.ASTR.IM]Physics [physics]/Astrophysics [astro-ph]/Instrumentation and Methods for Astrophysic [astro-ph.IM] ,data acquisition ,interferometer ,General Physics and Astronomy ,FOS: Physical sciences ,detector: noise ,General Relativity and Quantum Cosmology (gr-qc) ,01 natural sciences ,General Relativity and Quantum Cosmology ,Optics ,0103 physical sciences ,Calibration ,detector: calibration ,KAGRA ,laser: interferometer ,[PHYS.PHYS.PHYS-INS-DET]Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det] ,010306 general physics ,Instrumentation and Methods for Astrophysics (astro-ph.IM) ,Physics ,010308 nuclear & particles physics ,business.industry ,geophysics ,Detector ,gravitational radiation ,KAGRA gravitational wave kamioka ,gravitational radiation detector ,Characterization (materials science) ,detector: sensitivity ,Interferometry ,F32 Calibration and operation of gravitational wave detector ,[PHYS.GRQC]Physics [physics]/General Relativity and Quantum Cosmology [gr-qc] ,Dewey Decimal Classification::500 | Naturwissenschaften::530 | Physik ,Astrophysics - Instrumentation and Methods for Astrophysics ,business ,detector: sensitivity, data acquisition, interferometer, geophysics, detector: noise, detector: calibration, KAGRA, gravitational radiation detector, gravitational radiation, laser: interferometer - Abstract
KAGRA is a newly built gravitational wave observatory, a laser interferometer with a 3 km arm length, located in Kamioka, Gifu, Japan. In this series of articles, we present an overview of the baseline KAGRA, for which we finished installing the designed configuration in 2019. This article describes the method of calibration (CAL) used for reconstructing gravitational wave signals from the detector outputs, as well as the characterization of the detector (DET). We also review the physical environmental monitors (PEM) system and the geophysics interferometer (GIF). Both are used for characterizing and evaluating the data quality of the gravitational wave channel. They play important roles in utilizing the detector output for gravitational wave searches. These characterization investigations will be even more important in the near future, once gravitational wave detection has been achieved, and in using KAGRA in the gravitational wave astronomy era., Comment: 2021/02/08 Accepted by PTEP
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- 2021
85. J-PARC E07: Systematic Study of Double Strangeness System with Hybrid Emulsion Method
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Megumi Naruki, R. Kiuchi, Kazuya Watanabe, S. H. Hwang, A. Koshikawa, Y. Sasaki, J. W. Lee, K. Ito, A. Iskendir, Yuki Sato, A. N. L. Nyaw, T. Nanamura, T. Takeda, Shoichi Hasegawa, S. Y. Matsumoto, Junya Yoshida, Yuki Fujikawa, M. Ichikawa, Masahiro Yoshimoto, Manabu Moritsu, Takayoshi Kawai, Hiroki Ito, K. Miwa, Hitoshi Takahashi, Y. Ogura, Hiroyuki Ekawa, C. S. Yoon, K. Imai, K. Inaba, D. H. Zhang, H. Kanauchi, W. S. Jung, Yoshiro Takahashi, Hitoshi Sugimura, Kazuma Nakazawa, T. Hashimoto, Manami Fujita, J. Y. Sohn, Jihwa Lee, Shunsuke Kanatsuki, K. Tanida, H. Sako, T. L. Ma, T. Hayakawa, A. T. Moe, M. Hirose, S. Kinbara, D. Nakashima, M. H. Kim, K. Oue, Y. Nakada, T. J. Moon, M. Minakawa, Myint Kyaw Soe, T. Takahashi, K. Agari, E. Umezaki, Toyoki Watabe, Seongbae Yang, S. Ashikaga, Y. C. Han, Yoshikazu Ishikawa, Mifuyu Ukai, M. Ohashi, Masaharu Ieiri, Kazuhiro Suzuki, Aye Moh Moh Theint, Kensuke Kobayashi, M. M. Soe, K. Hosomi, Manami Nakagawa, K. Hicks, S. Hoshino, Kotaro Shirotori, Yuya Akazawa, S. Y. Ryu, S. H. Kim, E. Hayata, B. Bassalleck, A. Kasagi, Z. Zhang, J. K. Ahn, J. Pochodzalla, Khin Than Tint, Shuhei Hayakawa, T. O. Yamamoto, Takeshi Koike, Y. Toyama, S. Sato, S. Ozawa, N. Fujioka, Ryotaro Honda, Yoko Endo, Y. Ichikawa, T. Akaishi, K. Hoshino, Erina Hirose, S. Bleser, Y. Nagase, Hitoshi Tamura, F. Schupp, Hidetaka Kobayashi, and R. Goto
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Nuclear physics ,Physics ,Emulsion ,J-PARC ,Strangeness - Published
- 2021
86. The Treatment Outcomes of Stereotactic Body Radiotherapy for Bone Oligo-Metastatic Disease
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K. Ito, Kumiko Karasawa, and H. Ogawa
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Cancer Research ,medicine.medical_specialty ,Univariate analysis ,Radiation ,Performance status ,business.industry ,medicine.medical_treatment ,Bone metastasis ,Common Terminology Criteria for Adverse Events ,medicine.disease ,Metastasis ,Radiation therapy ,Prostate cancer ,Oncology ,medicine ,Radiology, Nuclear Medicine and imaging ,Radiology ,Progression-free survival ,business - Abstract
Purpose/Objective(s) Stereotactic body radiotherapy (SBRT) has been increasingly expected to be a treatment option for bone metastases, especially in oligometastatic disease (OMD). This study aimed to clarify the efficacy of SBRT for bone oligo-metastases. Materials/Methods Patients who met the following criteria were retrospectively reviewed from a prospective database; 1) with bone metastases, 2) treated with SBRT for bone metastases and 3) with active lesion less than 5 in 3 different sites. OMD was defined as the patients with active lesion less than 5 in 3 different sites. Progression free survival (PFS), local failure (LF), overall survival (OS) and adverse events (AEs) were evaluated. LF was estimated using the cumulative incidence function adjusted for the competing risk of death. AEs were evaluated based on Common Terminology Criteria for Adverse Events 5.0. Results There were 219 cases in 188 patients selected from our database showed: median age, 66 years (range, 23-85 years); performance status, 0/1/2/3/4, 123/74/13/6/3; lesion histopathology, lung/prostate/ colorectal/breast/thyroid/kidney/others, 35/31/22/21/21/21/68; region of bone metastases, spine/non-spine, 139/80; number of metastases, 1/2/3/4/5, 146/45/20/6/2; type of OMD, synchronous OMD/metachronus OMD/repeat OMD/induced OMD, 39/93/64/23; treatment for primary site, local therapy/systemic therapy/none, 196/20/3; systemic therapy before SBRT, yes/no, 96/123; systemic therapy after SBRT, yes/no/unknown, 105/111/3; median interval from upfront treatment, 36 months (range, 1-300 months); radiotherapy history for targeted lesion, yes/no, 49/170; the prescribed dose, 20 Gy in single fraction/24 Gy in 2 fractions/30 Gy in 5 fractions/35 Gy in 5 fractions, 9/121/21/68. Median follow-up after SBRT was 16 months (range, 1-82 months). The 1-year PFS rate, LF rate and OS rate were 43.1%, 12.8% and 89.7%, respectively. The median PFS was 11 months. Most dominant first failure pattern was another bone metastasis. In univariate analysis of PFS, good performance status (P = 0.028), metastasis from prostate cancer (P = 0.00052) and longer interval from upfront treatment (P = 0.012) were associated with a significant better prognosis. In multivariate analysis, metastasis from prostate cancer (P = 0.010) and interval from upfront treatment (P = 0.019) were independent prognostic factors. In the cases excluding prostate cancer, median PFS was 9 months and the 1-year PFS rate was 39.4%. In 111 cases with treated before December 2018, 2-year progression-free survival was achieved in 22 cases (19.8%). Grade 5 infection, grade 4 radiation myelopathy and grade 3 dermatitis were observed in one case, respectively. Seventeen cases of fracture were encountered. Conclusion SBRT for bone oligo-metastases provided long term systemic disease control in about 20% of cases. SBRT is effective treatment option for bone OMD especially for the cases with long interval from upfront treatment.
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- 2021
87. 545P First-in-human (FIH) study of E7130 in patients (pts) with advanced solid tumors: Primary result of dose-escalation part
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S. Takahashi, Makiko Ono, Toshihiko Doi, T. Hisai, Yasutoshi Kuboki, Yoichi Naito, Nobuaki Matsubara, Hiroki Ikezawa, Akihiro Ohmoto, Kenichi Harano, K. Ito, S. Shiba, A. Mikubo, Tetsuya Urasaki, and O. Asano
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Oncology ,medicine.medical_specialty ,business.industry ,Internal medicine ,Dose escalation ,Medicine ,In patient ,Hematology ,First in human ,business - Published
- 2021
88. Observation of Coulomb-Assisted Nuclear Bound State of Ξ−–N14 System
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S. Bleser, Hitoshi Sugimura, S H Hayakawa, T. Takeda, T. L. Ma, H. Kanauchi, D. H. Zhang, Junya Yoshida, T. Hayakawa, Z. Zhang, Khin Than Tint, M. Minakawa, M. H. Kim, M. Hirose, T. J. Moon, S. Y. Matsumoto, R. Kiuchi, T. Takahashi, Manami Nakagawa, E. Hayata, Jihwa Lee, Y. Nakada, Hitoshi Tamura, F. Schupp, Hidetaka Kobayashi, Hiroyuki Ekawa, K. Agari, Yudai Ichikawa, M. Ohashi, Kotaro Shirotori, Yoko Endo, B. Bassalleck, A. Kasagi, Satoshi Sato, R. Goto, E. Umezaki, K. Ito, Manabu Moritsu, S. Ashikaga, Yuya Akazawa, Masahiro Yoshimoto, Yoshikazu Ishikawa, K. Miwa, Hiroyuki Sako, Yuki Fujikawa, M. Ichikawa, J. Pochodzalla, S. Y. Ryu, A. T. Moe, Kenichi Imai, Hiroki Ito, Kazuya Watanabe, Takashi Yamamoto, S. H. Hwang, K. Inaba, S. Ozawa, N. Fujioka, S. H. Kim, Hitoshi Takahashi, Erina Hirose, Shoichi Hasegawa, Y. Nagase, R Honda, Seongbae Yang, K. Hicks, S. Hoshino, T. Hashimoto, J. Y. Sohn, T. Akaishi, Yuki Sato, A. N. L. Nyaw, T. Nanamura, Shunsuke Kanatsuki, Y. Toyama, Aye Moh Moh Theint, M. M. Soe, Myint Kyaw Soe, Takeshi Koike, Y Han, J. K. Ahn, Kenji Hosomi, Kensuke Kobayashi, S. Kinbara, K. Hoshino, Megumi Naruki, A. Koshikawa, K. Tanida, C. S. Yoon, Manami Fujita, D. Nakashima, K. Oue, Toyoki Watabe, W. S. Jung, Kazuma Nakazawa, Takayoshi Kawai, Y. Ogura, Mifuyu Ukai, and Kazuhiro Suzuki
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Physics ,Binding energy ,Hyperon ,General Physics and Astronomy ,State (functional analysis) ,Coupling (probability) ,01 natural sciences ,0103 physical sciences ,Bound state ,Coulomb ,Absorption (logic) ,Atomic physics ,010306 general physics ,Energy (signal processing) - Abstract
In an emulsion-counter hybrid experiment performed at J-PARC, a Ξ^{-} absorption event was observed which decayed into twin single-Λ hypernuclei. Kinematic calculations enabled a unique identification of the reaction process as Ξ^{-}+^{14}N→_{Λ}^{10}Be+_{Λ}^{5}He. For the binding energy of the Ξ^{-} hyperon in the Ξ^{-}-^{14}N system a value of 1.27±0.21 MeV was deduced. The energy level of Ξ^{-} is likely a nuclear 1p state which indicates a weak ΞN-ΛΛ coupling.
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- 2021
89. Cep57 and Cep57L1 maintain centriole engagement in interphase to ensure centriole duplication cycle
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Shoji Hata, Daiju Kitagawa, Koki Watanabe, Kyohei Matsuhashi, Takumi Chinen, Haruki Ishida, and Kei K. Ito
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Centriole ,Cell cycle progression ,Cell Cycle Proteins ,Spindle Apparatus ,Protein Serine-Threonine Kinases ,Biology ,Models, Biological ,Article ,Chromosome segregation ,03 medical and health sciences ,0302 clinical medicine ,Chromosome Segregation ,Proto-Oncogene Proteins ,Humans ,Amino Acid Sequence ,Interphase ,Mitosis ,Centrioles ,030304 developmental biology ,Centrosome ,0303 health sciences ,Sequence Homology, Amino Acid ,Nuclear Proteins ,Centriole duplication ,Cell Biology ,Cell cycle ,Cell biology ,Protein Transport ,HEK293 Cells ,Phenotype ,Microtubule-Associated Proteins ,030217 neurology & neurosurgery ,HeLa Cells ,Cell Cycle and Division - Abstract
Ito et al. revealed that centrosomal proteins Cep57 and Cep57L1 cooperatively maintain centriole engagement during interphase in human cells. Codepletion of Cep57 and Cep57L1 induces precocious centriole disengagement in interphase, which results in centriole reduplication, centriole amplification, and chromosome segregation errors., Centrioles duplicate in interphase only once per cell cycle. Newly formed centrioles remain associated with their mother centrioles. The two centrioles disengage at the end of mitosis, which licenses centriole duplication in the next cell cycle. Therefore, timely centriole disengagement is critical for the proper centriole duplication cycle. However, the mechanisms underlying centriole engagement during interphase are poorly understood. Here, we show that Cep57 and Cep57L1 cooperatively maintain centriole engagement during interphase. Codepletion of Cep57 and Cep57L1 induces precocious centriole disengagement in interphase without compromising cell cycle progression. The disengaged daughter centrioles convert into centrosomes during interphase in a Plk1-dependent manner. Furthermore, the centrioles reduplicate and the centriole number increases, which results in chromosome segregation errors. Overall, these findings demonstrate that the maintenance of centriole engagement by Cep57 and Cep57L1 during interphase is crucial for the tight control of centriole copy number and thus for proper chromosome segregation.
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- 2021
90. Search for anisotropic gravitational-wave backgrounds using data from Advanced LIGO and Advanced Virgo's first three observing runs
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A. Grimaldi, M. A. Barton, Samuele Cortese, Charlie Hoy, Charalampos Markakis, L. Trozzo, Albert Lazzarini, Benno Willke, A. Grado, P. Booker, C. Cahillane, Norichika Sago, J. Hennig, V. Gayathri, J. Baird, M. Jeunon, Sascha Husa, Samaya Nissanke, S. Walsh, A. Hreibi, M. J. Szczepańczyk, M. Chaturvedi, G. Venugopalan, S. R. Mohite, Alessandra Buonanno, Gabrielle Allen, H. Y. Cheung, Rana X. Adhikari, Om Sharan Salafia, F. Donovan, Edoardo Milotti, B. Lantz, M. A. Bizouard, B. K. Berger, Denis Martynov, Claudia Moreno, N. V. Krishnendu, Marco Bazzan, Satoshi Tsuchida, C. Ingram, D. A. Melchor, F. Marion, E. Goetz, Matthew Giesler, D.B. DeBra, Giuseppe Castaldi, S. G. Crowder, K. Ito, E. Lalande, M. Cannavacciuolo, E. N. Clark, Geoffrey Lovelace, L. Nguyen Quynh, J. D. E. Creighton, Lijing Shao, M. Carpinelli, J. Liu, A. Pasqualetti, R. Bajpai, F. Garufi, Archana Pai, Surendra Nadh Somala, Yoshiyuki Obuchi, C. Talbot, Carl-Johan Haster, S. Nozaki, H. Sun, V. JaberianHamedan, Tyson Littenberg, T. Washimi, T. D. Creighton, L. A. Rees, Silvia Corezzi, S. Bae, Kai-Feng Chen, F. Paoletti, Felice Sorrentino, C. L. Chan, P. Szewczyk, A. K. Prajapati, M. Patel, C. M. Mow-Lowry, Sergey P. Vyatchanin, L. Aiello, Luigi Troiano, M. Gosselin, R. Green, H. Yuzurihara, D. Hoyland, B. F. Whiting, J. Casanueva Diaz, V. M. Bedakihale, Masako Kakizaki, R. Maggiore, C. Van Den Broeck, E. Sowell, E. Coccia, M. E. Zucker, B. A. Weaver, G. Vajente, S. M. Gaebel, T. Shimoda, Y. Okutani, J. G. Rollins, A. Mhaske, H. Hansen, T. Wlodarczyk, Laura Cadonati, L. Rolland, S. T. Countryman, S. Penn, R. M. S. Schofield, K. Mogushi, H. Estelles, Y. Huang, P. A. Duverne, S. Karki, D. Moraru, A. Dmitriev, E. Floden, V. B. Adya, A. Renzini, G. L. Mansell, Y. K. Lecoeuche, G. M. Harry, L. Naticchioni, T. Shishido, Salvatore Vitale, A. Cumming, F. Di Renzo, Gianpietro Cagnoli, L.-W. Wei, S. Katsanevas, Madeline Wade, M. Tse, D. S. Tsai, D. M. Macleod, T. D. Ramirez, M. T. Hübner, Yasufumi Kojima, J. F. J. van den Brand, C. Pluchar, P. Chanial, Abhirup Ghosh, S. Sunil, M. Tacca, G. Kang, E. Capote, A. K. Mehta, N. Man, H. Pang, K. A. Strain, K. Haughian, P. Ruggi, A. Puecher, A. Mullavey, T. J. N. Nelson, Filip Morawski, P. J. Easter, G. Guixé, Xiaohui Fan, P. Leaci, Y. R. Chen, Alessandro Bertolini, J. C. Driggers, John A. Clark, Ben Farr, Fabrizio Barone, Giuseppe Intini, D. Rozza, V. Dattilo, Tejinder Kaur, Edwin J. Son, Isobel M. Romero-Shaw, T. C. Pechsiri, Umakant D. Rapol, G. S. Wallace, Stefan Hild, J. D. Jones, A. C. Baylor, L. M. DaneshgaranBajastani, R. Huxford, Surabhi Sachdev, Christopher J. Moore, V. V. Frolov, Kazuhiro Hayama, K. Venkateswara, R. Cotesta, R. Mittleman, Kentaro Komori, Soubhik Kumar Bhaumik, Yuri Levin, Akito Araya, J. Von Wrangel, T. Kajita, L. Kleybolte, S. Oshino, G. S. Davies, T. Huynh-Dinh, Hajime Sotani, A. Z. Jan, C. Makarem, Martin Hendry, Cecilio García-Quirós, Hong Wu, J.-G. Ducoin, Richard O'Shaughnessy, B. Barr, M. C. Díaz, A. Menendez-Vazquez, P. Figura, C. M. Compton, Antonios Kontos, B. L. Swinkels, Wei-Tou Ni, V. Tiwari, K. A. Thorne, Hisa-aki Shinkai, Isabel Cordero-Carrión, S. Wu, Ll. M. Mir, Junwei Cao, R. Kirchhoff, S. P. Jadhav, M. C. Heintze, Yann Bouffanais, V. Fafone, A. Pereira, J. A. Rocha, Nelson Christensen, S. A. Usman, E. G. Seo, E. K. Porter, Kendall Ackley, R. K. Nayak, A. Allocca, Marco Romanelli, Christophe Collette, C. J. Perez, B. D. O'Brien, R. P. Udall, R. C. Walet, C. Di Fronzo, T. R. Saravanan, J. Zhang, L. F. Ortega, V. P. Mitrofanov, R. Cummings, G. Koekoek, J. Betzwieser, M. Zhan, D. W. Yeeles, Antoine Heidmann, A. Brillet, G. Eddolls, A. D. Viets, D. Meacher, E. N. Tapia San Martin, K. Haris, F. Vetrano, Z. Hong, K. Kaihotsu, S. E. Dwyer, David Keitel, A. Hagiwara, L. C. Strang, R. L. Savage, Chunglee Kim, F. W. Yang, J. S. Kissel, H. Cao, Marc Favata, A. J. Weinstein, Fumihiro Uraguchi, Roger Jones, V. Villa-Ortega, David A. Williams, S. J. Cooper, N. Raza, I. W. Harry, C-Y. Lin, N. Y. Washington, N. Letendre, Nikhil Sarin, J. Heinzel, Thanh D. Nguyen, V. J. Roma, Leo Tsukada, E. Z. Hamilton, M. Matiushechkina, Nikita S. Shcheblanov, B. H. Hsieh, Y. Miyazaki, A. D. Huddart, N. Kawai, R. J. Trudeau, Anindita Ganguly, M. Diaz-Ortiz, J. Venneberg, W. Del Pozzo, P. F. Cohadon, K. E. Ramirez, H. Heitmann, D. Sawant, M. Laxen, Anchal Gupta, Kei Kotake, H. Y. Chia, E. Cuoco, N. A. Didio, E. N.Tapia San Mertin, Fabrizio Giulio Luca Pilo, F. E. Peña Arellano, A. Ueda, D. Lumaca, L. Xiao, A. P. Spencer, A. M. Farah, M. F. Carney, D. D. Brown, Chad Hanna, A. Bramley, Yue Zhao, C. Kimball, Sakae Araki, J. J. McCann, T. J. Slaven-Blair, S. ShyamSundar, C. Stachie, A. Parisi, J. Oberling, M. Pirello, Alena Ananyeva, A. Lartaux-Vollard, Suvadeep Bose, A. Depasse, A. F. Helmling-Cornell, Ajay Kumar, N. D. Ormsby, C. Whittle, Yuki Inoue, A. M. Gretarsson, C. Bradaschia, W-R. Xu, F. Carbognani, Yang Yang, Yoshiaki Himemoto, I. M. Pinto, I. La Rosa, Jean-René Cudell, C. De Rossi, Stanislav Babak, S. Sayah, H. Overmier, B. Garaventa, Nobutada Kimura, Ka Yee C. Lee, M. A. Okada, Matteo Pegoraro, Piero Rettegno, R. Gouaty, A. V. Bhandari, Z. Márka, M. Boer, Shubhanshu Tiwari, T. B. Edo, R. Gray, Masashi Ohkawa, V. Srivastava, Y. Aso, M. Fays, N. van Bakel, M. Leonardi, Osamu Miyakawa, Lior Cohen, R. Zhang, Ik Siong Heng, Geert Raaijmakers, P. Fulda, M. Mondin, K. Mason, S. Shibagaki, D. Rosińska, E. R. G. von Reis, Ray-Kuang Lee, F. Y. Khalili, Ofelia Durante, Jay D. Tasson, J. L. Willis, M. Eisenmann, Ofek Birnholtz, Sanjeev Dhurandhar, M. Merzougui, Sebastien Biscans, S. A. Nichols, A. Malik, S. Gaudio, G. Valdes, Pulak Ranjan Giri, A. Adams, I. Tosta e Melo, Deirdre Shoemaker, F. Robinet, J. K. Blackburn, Q. Chu, F. L. Linde, R. Tenorio, N. A. Holland, Yichen Huang, D. Sellers, G. R. Johns, S. Ponrathnam, Michael Williams, Moritz Mehmet, L. Terkowski, E. Cesarini, P. Kumar, A. Singha, Ken K. Y. Ng, M. Constancio, E. Chassande-Mottin, S. Galaudage, C. Darsow-Fromm, C. Di Giorgio, J. D. Callaghan, Torrey Cullen, G. Ge, A. Di Lieto, J. Sadiq, Angela Trapananti, Kopin Liu, M. Vasúth, W. Griffiths, Eric Howell, Sadakazu Haino, J. D. Merritt, A. Masserot, Sylvain Marsat, Yuichiro Sekiguchi, M. Nakano, Sheila Rowan, M. Ebersold, S. Márka, N. Sennett, C. Wu, K. Kawabe, Jimin George, M. Sieniawska, F. Kuei, Brynmor Haskell, Alberto Vecchio, Geoffrey Mo, Will M. Farr, M. Montani, F. K. Lin, Nancy Aggarwal, J. B. Carlin, Simone Mozzon, Patrice Hello, G. Pagliaroli, M. Was, Xin Chen, R. M. Martin, J. C. Barayoga, B. F. Neil, R. Robie, L. W. Luo, I. Molina, M. Landry, A. Tripathee, L. Di Fiore, B. Mours, F. Meylahn, C. Austin, N. W. Farrow, M. Barsuglia, A. L. Miller, Leo Singer, Bartosz Fornal, Shinji Miyoki, Matteo Breschi, W. Kastaun, H. Qi, K. Chandra, H. Vocca, S. Leavey, S. Eguchi, Hai-Ping Cheng, A. Iess, D. Ugolini, P. Jung, M. Bawaj, Lili Yang, J. Smetana, A. C. Utina, Riccardo Sturani, V. Bossilkov, A. Ramos-Buades, M. Bischi, Kiran Prasai, G. Ueshima, Kyujin Kwak, S. Nagano, V. Kringel, J. Bidler, R. Dean, A. B. Yelikar, D. Gao, E. Katsavounidis, K. Shimode, D. C. Y. Hui, F. Nocera, A. Grant, C. Zhao, D. Bankar, I. Dorrington, Xiuling Li, M. Branchesi, Xing-Jiang Zhu, Takuma Yamada, G. Vedovato, L. E. H. Datrier, Y. Sakai, I. Di Palma, J. Gais, L. K. Nuttall, R. Macas, G. Billingsley, D. Jariwala, K. Jung, R. Jaume, R. A. Eisenstein, Hee-Suk Cho, M. H. P. M. van Putten, Jishnu Suresh, L. Prudenzi, T. Zelenova, Riccardo Bassiri, D. B. Kozak, C. Vorvick, Ryan Magee, Nandita Khetan, R. Tso, M. Kovalam, Alec Mishkin, R. Cavalieri, Magnus Manske, A. K. Srivastava, A. E. Pace, K. Miyo, A. S. Hines, Roberto Chierici, P. Clearwater, S. Sudhagar, M. Pürrer, S. Kwang, I. Dave, S. Sato, D. Agarwal, Thierry Pradier, David Jones, A. Shoda, Marco Cavaglia, B. Hughey, N. Hirata, M. Curyło, Subroto Mukherjee, P. Astone, V. Kondrashov, Bruno Giacomazzo, L. Errico, D. B. Tanner, Kevin M. Ryan, Patrick M. Koch, Carmen S. Menoni, M. Korobko, T. Zhang, S. M. Aston, Michael W. Coughlin, Zhoujian Cao, I. Khan, S. Banagiri, T. Kawasaki, H. Radkins, J. Brooks, R. Musenich, M. Kamiizumi, J. Lange, Tania Regimbau, A. J. Tanasijczuk, A. M. Knee, K. Merfeld, Y. Tomigami, A. Viceré, Frances Hellman, K. Chakravarti, Arunava Mukherjee, Haruki Kitazawa, Fabio Marchesoni, J. Park, A. Chiummo, Kyungmin Kim, Debarati Chatterjee, B. O'Reilly, P. Gruning, Mario Spera, Peter Aufmuth, T. L. Lam, K. W. Tsang, E. J. Fauchon-Jones, Atsushi Nishizawa, Gianluca Grignani, D. Y. T. Pong, A. Gennai, A. Ain, E. Massera, Y. Asali, Y. Bae, D. Schaetzl, Thibaut Jacqmin, C. Olivetto, A. Yoon, M. Lormand, L. Zhang, D. Töyrä, O. Sauter, S. B. Anderson, K. M. Aleman, Graham Woan, Robert L. Byer, Stuart Reid, Riccardo Ciolfi, Yi Chen, Harald P. Pfeiffer, Peter T. H. Pang, Tomasz Bulik, T. Tomura, Francesco Chiadini, F. J. Hayes, A. Basti, C. I. Torrie, Alessandro Longo, Jürgen Heinze, K. Oohara, E. Maros, J. Glanzer, Manel Molina-Ruiz, Edward Seidel, Richard J. Oram, A. Bozzi, S. B. Coughlin, W. G. Anderson, G. Cella, Ryan N. Lang, D. D'Urso, Krzysztof Piotrzkowski, B. W. Schulte, Vuk Mandic, D. J. Stops, S. Ide, Y. Minenkov, M. Turconi, J. Junker, H. M. Lee, Jessica Steinlechner, M. Pracchia, A. Neunzert, Norikatsu Mio, D. Sentenac, M. Heurs, J. S. H. Lee, P. Couvares, Patrick Brady, T. Dal Canton, Felix Wellmann, J. Warner, Podila Satya Venkata Narasimha Sharma, E. K. Gustafson, M. Rizzo, G. Cho, Pablo Cerdá-Durán, Vivien Raymond, A. A. Ciobanu, David E. McClelland, J. C. Bayley, J.-P. Coulon, François Bondu, H. Chu, M. Kolstein, P. J. Veitch, M. Ball, M. L. Lollie, P. J. Sutton, M. Deenadayalan, Sung-Po Chao, R. De Simone, S. Ghosh, D. Passuello, F. Badaracco, E. A. Chase, Z. Frei, Jacob Scheuer, Astrid Lamberts, J. Woehler, S. V. Angelova, Kyohei Kawaguchi, I. Michaloliakos, R. Passaquieti, G. Pagano, Reed Essick, C. Nguyen, N. Kita, J. N. Hohmann, C. Jeon, A. Cirone, R. Coyne, Fabrice Matichard, R. De Rosa, Kazuyuki Tanaka, Bernard F. Schutz, Kwan-Lok Li, M. Ying, M. Saleem, Veronica Granata, Yi-Ting Hsu, M. Haney, A. Balsamo, S. Khadka, Marta Colleoni, Yuta Michimura, P. Thomas, M. Arène, J. A. Giaime, I. Nardecchia, A. Amato, L. E. Wade, B. U. Gadre, A. C. Green, J. Z. Wang, Y-K. Chu, K. Yokogawa, D. Corre, Y. M. Kim, R. G. Ormiston, Hyun Lee, J. Calderón Bustillo, Safura Sharifi, J. H. Romie, B. Edelman, G. Mendell, C. Rajan, S. Kandhasamy, M. Fishbach, R. Abbott, Samuel Deléglise, S. J. Jadhav, A. R. Williamson, A. Miyamoto, Felipe Guzman, I. Belahcene, Albert K. H. Kong, B. Sorazu, E. O'Shea, Y. Nakayama, Piotr Jaranowski, Kazuhiro Yamamoto, Geraint Pratten, H. Fair, H. W. Lee, Robert J. McCarthy, S. Takano, Linqing Wen, T. A. Callister, G. Kuehn, T. Sekiguchi, László Á. Gergely, A. Macquet, M. Boldrini, Philip F. Hopkins, Y. Kao, Fausto Acernese, K. Kuns, C-Y. Chiang, Laurent Pinard, Shaon Ghosh, F. J. Raab, N. Mukund, V. Savant, Valérie Martinez, M. Cieślar, Terry G. McRae, Takahiro Tanaka, J. B. Kanner, Li Ju, Yoshio Arai, Brittany Kamai, Andreu Sanuy, Y. Hiranuma, A. Fernandez-Galiana, Hideki Asada, C. V. Kalaghatgi, J. Hanson, H. Fong, G. Greco, Zong-Hong Zhu, Francesco Pannarale, A. L. Stuver, David Coward, A. Miani, Jan Harms, A. S. Sengupta, D. Bhattacharjee, Daniele A. Steer, H. Satari, D. Bersanetti, G. Ashton, B. Ikenoue, T. Yamamoto, E. Fenyvesi, C. Messenger, Fabrizio Bobba, Stephan Grimm, F. Hernandez Vivanco, C. H. Chan, E. Payne, Takashi Uchiyama, C. Gray, I. Fiori, A. K. Zadrożny, S. Ha, Kohei Yamamoto, T. J. Shaffer, Tomotada Akutsu, Shawn Rosofsky, H-S. Kuo, C. Osthelder, Daichi Tsuna, Anupreeta More, Y. Kuromiya, P. Relton, Michela Mapelli, Z. Chen, T. Mishra, R. Gustafson, G. A. Prodi, Andrea Chincarini, Minkyun Noh, Cesare Barbieri, Walter Winkler, A. S. Markosyan, R. DeSalvo, T. Z. Summerscales, A. Lemaître, J. N. Linley, F. Cipriano, Soichiro Morisaki, M. Bals, N. Radulesco, Kunihito Ioka, L. G. Prokhorov, Harald Lück, E. Knyazev, D. Verkindt, A. Rocchi, B. Goncharov, R. Birney, Zachariah B. Etienne, D. Lopez, Y. Drori, Jennifer Watchi, V. Boschi, M. van Beuzekom, H. L. Lin, A. L. James, Jade Powell, V. Mangano, C. Pankow, P. Dupej, M. Mantovani, Eric B. Flynn, J. Kume, Jianfang Wang, B. Gateley, A. Sur, T. Di Girolamo, Aaron Buikema, Hang Yu, N. Leroy, Kentaro Somiya, Iii H.W. Cain, D. Tsai, Christos Karathanasis, Eric Thrane, P. Barneo, W. Katzman, A. F. Vargas, T. Sadecki, Sheon Chua, R. Bonnand, Mariana Fazio, S. C. McGuire, J. F. Read, S. Di Pace, S. Otabe, Toshikazu Suzuki, Aldo Ejlli, M. Piendibene, M. K. M. Bader, D. L. Ferguson, Y. Sakuno, Miriam Lucio Martinez, Michael Thomas, S. Biscoveanu, W. Ogaki, E. Polini, B. Bécsy, Matthias H. Hennig, N. Van Remortel, Des Gibson, H. K. Gulati, Hiroyuki Nakano, Eric Grimes, P. M. Meyers, A. Branch, K. Sakai, J. V. van Heijningen, C. C. Wipf, M. Fyffe, S. Koley, M. Brinkmann, P. Prosposito, S. Grunewald, R. Prasanna, P. Popolizio, Koji Arai, Gabriela Gonzalez, K. R. Corley, S. Choudhary, J. N. Leviton, D. Pascucci, T. Uehara, R. Gamba, M. J. Cowart, M. Nery, S. Raja, S. Maliakal, Yuka Fujii, O. V. Palashov, Sean T. McWilliams, F. Piergiovanni, D. E. Cohen, C. Michel, Maria Luisa Chiofalo, A. E. Gleckl, Rajesh Kumar, Kuo-Chuan Pan, I. Maksimovic, A. Effler, A. Franke, Vivishek Sudhir, C. C. Kuo, R. L. Ward, G. Hemming, Valeria Sipala, David H. Reitze, H. Masalehdan, D. Buskulic, Rahul Kashyap, C. McIsaac, N. De Lillo, N. Sorrentino, W. Jia, H. Zhang, I. J. Hollows, D. H. Shoemaker, James Healy, Y. Moriwaki, Masaki Ando, H. Vahlbruch, Gunnar Riemenschneider, J. C. Mills, K. Riles, K. Kusayanagi, J. Y. Vinet, H. Middleton, C. Affeldt, Ettore Majorana, R. P. Fisher, S. Mitra, M. Zevin, M. Fukunaga, S. Frasca, Jonathan Richardson, Sarah Caudill, M. P. Thirugnanasambandam, E. J. Sanchez, D. Tuyenbayev, Maria Ilaria Del Principe, Yogesh Verma, Kai Staats, S. Mastrogiovanni, L. Conti, Yi Yang, M. Agathos, S. Choate, S. Tanioka, Soumen Roy, Alejandro Torres-Forné, R. Negishi, P. Gupta, Giovanni Carapella, Otto A. Hannuksela, L. Pierini, P. Brockill, Albino Perego, A. Vajpeyi, T. D. Knowles, Gregorio Carullo, G-Z. Huang, Paul M. Ricker, B. Biswas, Marica Valentini, D. P. Kapasi, J. Zweizig, William Parker, Yoshihiko Saito, Shreya Anand, E. L. Merilh, Shrobana Ghosh, M. Davier, Rosalba Fittipaldi, Anuradha Gupta, Kunihiro Nagano, Carl Blair, T. J. Hansen, M. Shikauchi, F. Gissi, M. Bitossi, Jordan Camp, D. Tao, M. Weinert, H. A. G. Gabbard, Rakesh Kumar, M. Khursheed, E. J. Marx, F. Fidecaro, F. Bergamin, G. M. Guidi, Sebastian Steinlechner, C. A. Rose, S. Karat, J. Neilson, Hideaki Hayakawa, K. Wette, John J. Oh, Timothy Evans, T. Etzel, F. Cleva, M. P. Ross, S. Rodriguez, A. E. Tolley, John Veitch, M. Pichot, Sebastien Clesse, N. Bode, Maximiliano Isi, J. Lehmann, J. O'Dell, Ernesto Placidi, P. Ciecielag, Dániel Barta, C. S. Unnikrishnan, M. G. Benjamin, B. Cousins, Rory Smith, C. Adams, O. J. Piccinni, R. D. Rodriguez-Soto, Gor Oganesyan, C. Frederick, HyunGyu Suh, Doğa Veske, J. P. Zendri, A. F. Brooks, P. J. Quinonez, R. M. Blair, D. Sigg, C. García-Núñez, S. W. Ballmer, C. Kozakai, M. Takeda, E. M. Gretarsson, Ying Guo, D. Beniwal, J. McIver, Peter Fritschel, Wenxiao Wang, D. Davis, V. Valsan, E. Bonilla, Karsten Danzmann, T. Harder, Andrea H. Tapia, K. S. Phukon, Javier Sánchez, M. Masso-Reid, Michelle E. Walker, Z. J. Holmes, V. Del Favero, J. Eichholz, G. Moreno, H. Inchauspe, Y. Fujikawa, K. Isleif, Naoki Aritomi, E. Schwartz, A. W. Criswell, Lindsay DeMarchi, J. Petermann, Kenta Tanaka, A. Schindler-Tyka, Kimio Tsubono, J. Vanosky, Kazuhiro Agatsuma, M. Punturo, M. BenYaala, B. C. Pant, C. Messick, Matthew Evans, S. J. Rowlinson, D. Petterson, C. Magazzù, N. Arnaud, P. J. King, Jun'ichi Yokoyama, J. G. Guerrero, K. A. Pham, Frank Ohme, E. Leon, O. Halim, S. Klimenko, Ryutaro Takahashi, M. Tonelli, F. Muciaccia, M. J. Yap, K. Hattori, C. Palomba, L. E. Sanchez, K. J. Wagner, D. Hartwig, K. Okutomi, Anupam Sharma, Tim Dietrich, Lionel London, M. S. Shahriar, Sachiko Kuroyanagi, Imre Bartos, B. Idzkowski, V. Loriette, V. Skliris, Enrico Calloni, G. Traylor, S. Soni, Alexander C. Jenkins, Olivier Minazzoli, Thomas Corbitt, A. Markowitz, Takamasa Suzuki, Koya Arai, M. Razzano, Hiroki Takeda, B. Grace, Leopoldo Milano, G. Dálya, Guoying Zhao, C. Gier, Slawomir Gras, L. Salconi, C. A. Costa, S. W. S. Ng, S. M. Aronson, T. Tsang, Akiteru Takamori, N. Koper, Roman Schnabel, H. L. Griggs, R. K. Choudhary, M. Cifaldi, Prafulla K. Panda, V. Quetschke, Rainer Weiss, F. Ricci, X. Liu, Vijay Varma, D. Estevez, J. T. Whelan, M. MacInnis, Rémi Soulard, S. D'Antonio, H. B. Jin, S. Appert, Y. Setyawati, P. Rapagnani, J. E. Brau, J. Feicht, T. Mistry, V. Boudart, Souichi Telada, Aykutlu Dana, Martin M. Fejer, Hideyuki Tagoshi, J. R. Smith, R. Bork, S. Ghonge, P. B. Covas, Paul Hill, S. L. Nadji, Binlei Ding, Efim A. Khazanov, G. Ballardin, M. Caesar, David Blair, K. AultONeal, Robert Bruntz, Andreas Freise, Vincenzo Pierro, M. Pedraza, Z. Yang, R. Quitzow-James, N. N. Janthalur, T. Sawada, Paul D. Lasky, R. K. Hasskew, P. Shawhan, I. Ferrante, J. W. Westhouse, Rico K. L. Lo, D. Ganapathy, D. D. White, Matthew Pitkin, S. M. Scott, L. van der Schaaf, S. A. Pai, Satya Mohapatra, P. McClincy, D. J. McManus, Joey Shapiro Key, S. Meshkov, Seog Oh, S. Bernuzzi, A. M. Holgado, F. Martelli, Karan Jani, R. Shink, Monica Colpi, E. Capocasa, L. Rei, R. Kozu, Andrew Lundgren, W. S. Kim, Shuji Saito, S. D. Linker, P. Charlton, K. Yamashita, Gijs Nelemans, E. D. Hall, N. Bose, M. Granata, J. Bryant, Mark A. Scheel, K. Martinovic, O. Edy, C. Ooi, J. R. Sanders, Daniel E. Holz, B. J. J. Slagmolen, Dalziel J. Wilson, F. Clara, A. Lockwood, K. Holt, R. Shimizu, T. L. Carver, F. Cavalier, K. Hasegawa, S. C. Tait, A. Paolone, K. Shukla, Tatiana da Silva Pereira, F. Salemi, Koh Ueno, Peter Graham Jones, A. W. Jones, R. De Pietri, J. S. Areeda, T. Prestegard, V. Spagnuolo, S. Imam, Rocco Romano, M. Kinley-Hanlon, John D. Scott, R. A. Mercer, S. Ossokine, Jinsook Kim, Y. Mori, C. K. Cheong, Toshihiro Tsuzuki, Jonathan E. Thompson, Kohei Inayoshi, F. Aubin, G. Stratta, T. Yokozawa, Jesper Munch, Achamveedu Gopakumar, Guo-Chin Liu, B. B. Lane, Zifan Zhou, I. A. Bilenko, J. L. Mango, L. Mereni, M. De Laurentis, V. Benedetto, B. Patricelli, D. S. Wu, Margaret Millhouse, M. Kasprzack, David J. Ottaway, A. Paoli, S. G. Gaonkar, Haixing Miao, H. Ohta, S. L. Danilishin, C. Périgois, Santosh Roy, F. Di Giovanni, G. Bogaert, K. L. Dooley, Aaron Zimmerman, A. Romero, Taiki Tanaka, A. R. Guimaraes, Fangchen Feng, Hong Guo, Lisa Barsotti, T. Sato, Anirban Dasgupta, R. Sugimoto, M. Vardaro, Y. Bai, A. K. Divakarla, I. C. F. Wong, R. J. G. Jonker, C. Chan, Nobuyuki Kanda, J. Südbeck, Hartmut Grote, G. Losurdo, G. G. Fronzé, H. K. Tanaka, Eiichi Hirose, Kouji Nakamura, R. S. Bankar, M. C. 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D., Abraham, S., Acernese, F., Ackley, K., Adams, A., Adams, C., Adhikari, R. X., Adya, V. B., Affeldt, C., Agarwal, D., Agathos, M., Agatsuma, K., Aggarwal, N., Aguiar, O. D., Aiello, L., Ain, A., Ajith, P., Akutsu, T., Aleman, K. M., Allen, G., Allocca, A., Altin, P. A., Amato, A., Anand, S., Ananyeva, A., Anderson, S. B., Anderson, W. G., Ando, M., Angelova, S. V., Ansoldi, S., Antelis, J. M., Antier, S., Appert, S., Arai, Koya, Arai, Koji, Arai, Y., Araki, S., Araya, A., Araya, M. C., Areeda, J. S., Arène, M., Aritomi, N., Arnaud, N., Aronson, S. M., Asada, H., Asali, Y., Ashton, G., Aso, Y., Aston, S. M., Astone, P., Aubin, F., Aufmuth, P., Aultoneal, K., Austin, C., Babak, S., Badaracco, F., Bader, M. K. M., Bae, S., Bae, Y., Baer, A. M., Bagnasco, S., Bai, Y., Baiotti, L., Baird, J., Bajpai, R., Ball, M., Ballardin, G., Ballmer, S. W., Bals, M., Balsamo, A., Baltus, G., Banagiri, S., Bankar, D., Bankar, R. S., Barayoga, J. C., Barbieri, C., Barish, B. C., Barker, D., Barneo, P., Barone, F., Barr, B., Barsotti, L., Barsuglia, M., Barta, D., Bartlett, J., Barton, M. A., Bartos, I., Bassiri, R., Basti, A., Bawaj, M., Bayley, J. C., Baylor, A. C., Bazzan, M., Bécsy, B., Bedakihale, V. M., Bejger, M., Belahcene, I., Benedetto, V., Beniwal, D., Benjamin, M. G., Bennett, T. F., Bentley, J. D., Benyaala, M., Bergamin, F., Berger, B. K., Bernuzzi, S., Bersanetti, D., Bertolini, A., Betzwieser, J., Bhandare, R., Bhandari, A. V., Bhattacharjee, D., Bhaumik, S., Bidler, J., Bilenko, I. A., Billingsley, G., Birney, R., Birnholtz, O., Biscans, S., Bischi, M., Biscoveanu, S., Bisht, A., Biswas, B., Bitossi, M., Bizouard, M. -A., Blackburn, J. K., Blackman, J., Blair, C. D., Blair, D. G., Blair, R. M., Bobba, F., Bode, N., Boer, M., Bogaert, G., Boldrini, M., Bondu, F., Bonilla, E., Bonnand, R., Booker, P., Boom, B. A., Bork, R., Boschi, V., Bose, N., Bose, S., Bossilkov, V., Boudart, V., Bouffanais, Y., Bozzi, A., Bradaschia, C., Brady, P. R., Bramley, A., Branch, A., Branchesi, M., Brau, J. E., Breschi, M., Briant, T., Briggs, J. H., Brillet, A., Brinkmann, M., Brockill, P., Brooks, A. F., Brooks, J., Brown, D. D., Brunett, S., Bruno, G., Bruntz, R., Bryant, J., Buikema, A., Bulik, T., Bulten, H. J., Buonanno, A., Buscicchio, R., Buskulic, D., Byer, R. L., Cadonati, L., Caesar, M., Cagnoli, G., Cahillane, C., Cain, H. W., Bustillo, J. Calderón, Callaghan, J. D., Callister, T. A., Calloni, E., Camp, J. B., Canepa, M., Cannavacciuolo, M., Cannon, K. C., Cao, H., Cao, J., Cao, Z., Capocasa, E., Capote, E., Carapella, G., Carbognani, F., Carlin, J. B., Carney, M. F., Carpinelli, M., Carullo, G., Carver, T. L., Diaz, J. Casanueva, Casentini, C., Castaldi, G., Caudill, S., Cavaglià, M., Cavalier, F., Cavalieri, R., Cella, G., Cerdá-Durán, P., Cesarini, E., Chaibi, W., Chakravarti, K., Champion, B., Chan, C. -H., Chan, C., Chan, C. L., Chan, M., Chandra, K., Chanial, P., Chao, S., Charlton, P., Chase, E. A., Chassande-Mottin, E., Chatterjee, D., Chaturvedi, M., Chen, A., Chen, C., Chen, H. Y., Chen, J., Chen, K., Chen, X., Chen, Y. -B., Chen, Y. -R., Chen, Z., Cheng, H., Cheong, C. K., Cheung, H. Y., Chia, H. Y., Chiadini, F., Chiang, C-Y., Chierici, R., Chincarini, A., Chiofalo, M. L., Chiummo, A., Cho, G., Cho, H. S., Choate, S., Choudhary, R. K., Choudhary, S., Christensen, N., Chu, H., Chu, Q., Chu, Y-K., Chua, S., Chung, K. W., Ciani, G., Ciecielag, P., Cieślar, M., Cifaldi, M., Ciobanu, A. A., Ciolfi, R., Cipriano, F., Cirone, A., Clara, F., Clark, E. N., Clark, J. A., Clarke, L., Clearwater, P., Clesse, S., Cleva, F., Coccia, E., Cohadon, P. -F., Cohen, D. E., Cohen, L., Colleoni, M., Collette, C. G., Colpi, M., Compton, C. M., Constancio, M., Conti, L., Cooper, S. J., Corban, P., Corbitt, T. R., Cordero-Carrión, I., Corezzi, S., Corley, K. R., Cornish, N., Corre, D., Corsi, A., Cortese, S., Costa, C. A., Cotesta, R., Coughlin, M. W., Coughlin, S. B., Coulon, J. -P., Countryman, S. T., Cousins, B., Couvares, P., Covas, P. B., Coward, D. M., Cowart, M. J., Coyne, D. C., Coyne, R., Creighton, J. D. E., Creighton, T. D., Criswell, A. W., Croquette, M., Crowder, S. G., Cudell, J. R., Cullen, T. J., Cumming, A., Cummings, R., Cuoco, E., Curyło, M., Canton, T. Dal, Dálya, G., Dana, A., Daneshgaranbajastani, L. M., D’Angelo, B., Danilishin, S. L., D’Antonio, S., Danzmann, K., Darsow-Fromm, C., Dasgupta, A., Datrier, L. E. H., Dattilo, V., Dave, I., Davier, M., Davies, G. S., Davis, D., Daw, E. J., Dean, R., Debra, D., Deenadayalan, M., Degallaix, J., De Laurentis, M., Deléglise, S., Del Favero, V., De Lillo, F., De Lillo, N., Del Pozzo, W., Demarchi, L. M., De Matteis, F., D’Emilio, V., Demos, N., Dent, T., Depasse, A., De Pietri, R., De Rosa, R., De Rossi, C., Desalvo, R., De Simone, R., Dhurandhar, S., Díaz, M. C., Diaz-Ortiz, M., Didio, N. A., Dietrich, T., Di Fiore, L., Di Fronzo, C., Di Giorgio, C., Di Giovanni, F., Di Girolamo, T., Di Lieto, A., Ding, B., Di Pace, S., Di Palma, I., Di Renzo, F., Divakarla, A. K., Dmitriev, A., Doctor, Z., D’Onofrio, L., Donovan, F., Dooley, K. L., Doravari, S., Dorrington, I., Drago, M., Driggers, J. C., Drori, Y., Du, Z., Ducoin, J. -G., Dupej, P., Durante, O., D’Urso, D., Duverne, P. -A., Dwyer, S. E., Easter, P. J., Ebersold, M., Eddolls, G., Edelman, B., Edo, T. B., Edy, O., Effler, A., Eguchi, S., Eichholz, J., Eikenberry, S. S., Eisenmann, M., Eisenstein, R. A., Ejlli, A., Enomoto, Y., Errico, L., Essick, R. C., Estellés, H., Estevez, D., Etienne, Z., Etzel, T., Evans, M., Evans, T. M., Ewing, B. E., Fafone, V., Fair, H., Fairhurst, S., Fan, X., Farah, A. M., Farinon, S., Farr, B., Farr, W. M., Farrow, N. W., Fauchon-Jones, E. J., Favata, M., Fays, M., Fazio, M., Feicht, J., Fejer, M. M., Feng, F., Fenyvesi, E., Ferguson, D. L., Fernandez-Galiana, A., Ferrante, I., Ferreira, T. A., Fidecaro, F., Figura, P., Fiori, I., Fishbach, M., Fisher, R. P., Fittipaldi, R., Fiumara, V., Flaminio, R., Floden, E., Flynn, E., Fong, H., Font, J. A., Fornal, B., Forsyth, P. W. F., Franke, A., Frasca, S., Frasconi, F., Frederick, C., Frei, Z., Freise, A., Frey, R., Fritschel, P., Frolov, V. V., Fronzé, G. G., Fujii, Y., Fujikawa, Y., Fukunaga, M., Fukushima, M., Fulda, P., Fyffe, M., Gabbard, H. A., Gadre, B. U., Gaebel, S. M., Gair, J. R., Gais, J., Galaudage, S., Gamba, R., Ganapathy, D., Ganguly, A., Gao, D., Gaonkar, S. G., Garaventa, B., García-Núñez, C., García-Quirós, C., Garufi, F., Gateley, B., Gaudio, S., Gayathri, V., Ge, G., Gemme, G., Gennai, A., George, J., Gergely, L., Gewecke, P., Ghonge, S., Ghosh, Abhirup., Ghosh, Archisman, Ghosh, Shaon, Ghosh, Shrobana, Ghosh, Sourath, Giacomazzo, B., Giacoppo, L., Giaime, J. A., Giardina, K. D., Gibson, D. R., Gier, C., Giesler, M., Giri, P., Gissi, F., Glanzer, J., Gleckl, A. 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H., Huxford, R., Huynh-Dinh, T., Ide, S., Idzkowski, B., Iess, A., Ikenoue, B., Imam, S., Inayoshi, K., Inchauspe, H., Ingram, C., Inoue, Y., Intini, G., Ioka, K., Isi, M., Isleif, K., Ito, K., Itoh, Y., Iyer, B. R., Izumi, K., Jaberianhamedan, V., Jacqmin, T., Jadhav, S. J., Jadhav, S. P., James, A. L., Jan, A. Z., Jani, K., Janssens, K., Janthalur, N. N., Jaranowski, P., Jariwala, D., Jaume, R., Jenkins, A. C., Jeon, C., Jeunon, M., Jia, W., Jiang, J., Jin, H. -B., Johns, G. R., Jones, A. W., Jones, D. I., Jones, J. D., Jones, P., Jones, R., Jonker, R. J. G., Ju, L., Jung, K., Jung, P., Junker, J., Kaihotsu, K., Kajita, T., Kakizaki, M., Kalaghatgi, C. V., Kalogera, V., Kamai, B., Kamiizumi, M., Kanda, N., Kandhasamy, S., Kang, G., Kanner, J. B., Kao, Y., Kapadia, S. J., Kapasi, D. 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J., Richardson, J. W., Richardson, L., Ricker, P. M., Riemenschneider, G., Riles, K., Rizzo, M., Robertson, N. A., Robie, R., Robinet, F., Rocchi, A., Rocha, J. A., Rodriguez, S., Rodriguez-Soto, R. D., Rolland, L., Rollins, J. G., Roma, V. J., Romanelli, M., Romano, J., Romano, R., Romel, C. L., Romero, A., Romero-Shaw, I. M., Romie, J. H., Rose, C. A., Rosińska, D., Rosofsky, S. G., Ross, M. P., Rowan, S., Rowlinson, S. J., Roy, Santosh, Roy, Soumen, Rozza, D., Ruggi, P., Ryan, K., Sachdev, S., Sadecki, T., Sadiq, J., Sago, N., Saito, S., Saito, Y., Sakai, K., Sakai, Y., Sakellariadou, M., Sakuno, Y., Salafia, O. S., Salconi, L., Saleem, M., Salemi, F., Samajdar, A., Sanchez, E. J., Sanchez, J. H., Sanchez, L. E., Sanchis-Gual, N., Sanders, J. R., Sanuy, A., Saravanan, T. R., Sarin, N., Sassolas, B., Satari, H., Sato, S., Sato, T., Sauter, O., Savage, R. L., Savant, V., Sawada, T., Sawant, D., Sawant, H. 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E., Zweizig, J., The LIGO Scientific Collaboration, The Virgo Collaboration, The KAGRA Collaboration, Other Research IHEF (IoP, FNWI), Astroparticle Physics (IHEF, IoP, FNWI), IoP (FNWI), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP), Centre National de la Recherche Scientifique (CNRS)-Observatoire de la Côte d'Azur, Université Côte d'Azur (UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Université Côte d'Azur (UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Institut national des sciences de l'Univers (INSU - CNRS)-Université Nice Sophia Antipolis (... - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA), Institut National des Sciences Appliquées (INSA)-Université de Rennes (UNIV-RENNES)-Institut National des Sciences Appliquées (INSA)-École Nationale Supérieure des Sciences Appliquées et de Technologie (ENSSAT)-Centre National de la 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Lyon-Université de Lyon, Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS), Université Côte d'Azur (UCA)-Université Nice Sophia Antipolis (... - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Observatoire de la Côte d'Azur, Université Côte d'Azur (UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS), Abbott, R, Abbott, T, Abraham, S, Acernese, F, Ackley, K, Adams, A, Adams, C, Adhikari, R, Adya, V, Affeldt, C, Agarwal, D, Agathos, M, Agatsuma, K, Aggarwal, N, Aguiar, O, Aiello, L, Ain, A, Ajith, P, Akutsu, T, Aleman, K, Allen, G, Allocca, A, Altin, P, Amato, A, Anand, S, Ananyeva, A, Anderson, S, Anderson, W, Ando, M, Angelova, S, Ansoldi, S, Antelis, J, Antier, S, Appert, S, Arai, K, Arai, Y, Araki, S, Araya, A, Araya, M, Areeda, J, Arene, M, Aritomi, N, Arnaud, N, Aronson, S, Asada, H, Asali, Y, Ashton, G, Aso, Y, Aston, S, Astone, P, Aubin, F, Aufmuth, P, Aultoneal, K, Austin, C, Babak, S, Badaracco, F, Bader, M, Bae, S, Bae, Y, Baer, A, Bagnasco, S, Bai, Y, Baiotti, L, Baird, J, Bajpai, R, Ball, M, Ballardin, G, Ballmer, S, Bals, M, Balsamo, A, Baltus, G, Banagiri, S, Bankar, D, Bankar, R, Barayoga, J, Barbieri, C, Barish, B, Barker, D, Barneo, P, Barone, F, Barr, B, Barsotti, L, Barsuglia, M, Barta, D, Bartlett, J, Barton, M, Bartos, I, Bassiri, R, Basti, A, Bawaj, M, Bayley, J, Baylor, A, Bazzan, M, Becsy, B, Bedakihale, V, Bejger, M, Belahcene, I, Benedetto, V, Beniwal, D, Benjamin, M, Bennett, T, Bentley, J, Benyaala, M, Bergamin, F, Berger, B, Bernuzzi, S, Bersanetti, D, Bertolini, A, Betzwieser, J, Bhandare, R, Bhandari, A, Bhattacharjee, D, Bhaumik, S, Bidler, J, Bilenko, I, Billingsley, G, Birney, R, Birnholtz, O, Biscans, S, Bischi, M, Biscoveanu, S, Bisht, A, Biswas, B, Bitossi, M, Bizouard, M, Blackburn, J, Blackman, J, Blair, C, Blair, D, Blair, R, Bobba, F, Bode, N, Boer, M, Bogaert, G, Boldrini, M, Bondu, F, Bonilla, E, Bonnand, R, Booker, P, Boom, B, Bork, R, Boschi, V, Bose, N, Bose, S, Bossilkov, V, Boudart, V, Bouffanais, Y, Bozzi, A, Bradaschia, C, Brady, P, Bramley, A, Branch, A, Branchesi, M, Brau, J, Breschi, M, Briant, T, Briggs, J, Brillet, A, Brinkmann, M, Brockill, P, Brooks, A, Brooks, J, Brown, D, Brunett, S, Bruno, G, Bruntz, R, Bryant, J, Buikema, A, Bulik, T, Bulten, H, Buonanno, A, Buscicchio, R, Buskulic, D, Byer, R, Cadonati, L, Caesar, M, Cagnoli, G, Cahillane, C, Cain, H, Bustillo, J, Callaghan, J, Callister, T, Calloni, E, Camp, J, Canepa, M, Cannavacciuolo, M, Cannon, K, Cao, H, Cao, J, Cao, Z, Capocasa, E, Capote, E, Carapella, G, Carbognani, F, Carlin, J, Carney, M, Carpinelli, M, Carullo, G, Carver, T, Diaz, J, Casentini, C, Castaldi, G, Caudill, S, Cavaglia, M, Cavalier, F, Cavalieri, R, Cella, G, Cerda-Duran, P, Cesarini, E, Chaibi, W, Chakravarti, K, Champion, B, Chan, C, Chan, M, Chandra, K, Chanial, P, Chao, S, Charlton, P, Chase, E, Chassande-Mottin, E, Chatterjee, D, Chaturvedi, M, Chen, A, Chen, C, Chen, H, Chen, J, Chen, K, Chen, X, Chen, Y, Chen, Z, Cheng, H, Cheong, C, Cheung, H, Chia, H, Chiadini, F, Chiang, C, Chierici, R, Chincarini, A, Chiofalo, M, Chiummo, A, Cho, G, Cho, H, Choate, S, Choudhary, R, Choudhary, S, Christensen, N, Chu, H, Chu, Q, Chu, Y, Chua, S, Chung, K, Ciani, G, Ciecielag, P, Cieslar, M, Cifaldi, M, Ciobanu, A, Ciolfi, R, Cipriano, F, Cirone, A, Clara, F, Clark, E, Clark, J, Clarke, L, Clearwater, P, Clesse, S, Cleva, F, Coccia, E, Cohadon, P, Cohen, D, Cohen, L, Colleoni, M, Collette, C, Colpi, M, Compton, C, Constancio, M, Conti, L, Cooper, S, Corban, P, Corbitt, T, Cordero-Carrion, I, Corezzi, S, Corley, K, Cornish, N, Corre, D, Corsi, A, Cortese, S, Costa, C, Cotesta, R, Coughlin, M, Coughlin, S, Coulon, J, Countryman, S, Cousins, B, Couvares, P, Covas, P, Coward, D, Cowart, M, Coyne, D, Coyne, R, Creighton, J, Creighton, T, Criswell, A, Croquette, M, Crowder, S, Cudell, J, Cullen, T, Cumming, A, Cummings, R, Cuoco, E, Curylo, M, Canton, T, Dalya, G, Dana, A, Daneshgaranbajastani, L, D'Angelo, B, Danilishin, S, D'Antonio, S, Danzmann, K, Darsow-Fromm, C, Dasgupta, A, Datrier, L, Dattilo, V, Dave, I, Davier, M, Davies, G, Davis, D, Daw, E, Dean, R, Debra, D, Deenadayalan, M, Degallaix, J, De Laurentis, M, Deleglise, S, Del Favero, V, De Lillo, F, De Lillo, N, Del Pozzo, W, Demarchi, L, De Matteis, F, D'Emilio, V, Demos, N, Dent, T, Depasse, A, De Pietri, R, De Rosa, R, De Rossi, C, Desalvo, R, De Simone, R, Dhurandhar, S, Diaz, M, Diaz-Ortiz, M, Didio, N, Dietrich, T, Di Fiore, L, Di Fronzo, C, Di Giorgio, C, Di Giovanni, F, Di Girolamo, T, Di Lieto, A, Ding, B, Di Pace, S, Di Palma, I, Di Renzo, F, Divakarla, A, Dmitriev, A, Doctor, Z, D'Onofrio, L, Donovan, F, Dooley, K, Doravari, S, Dorrington, I, Drago, M, Driggers, J, Drori, Y, Du, Z, Ducoin, J, Dupej, P, Durante, O, D'Urso, D, Duverne, P, Dwyer, S, Easter, P, Ebersold, M, Eddolls, G, Edelman, B, Edo, T, Edy, O, Effler, A, Eguchi, S, Eichholz, J, Eikenberry, S, Eisenmann, M, Eisenstein, R, Ejlli, A, Enomoto, Y, Errico, L, Essick, R, Estelles, H, Estevez, D, Etienne, Z, Etzel, T, Evans, M, Evans, T, Ewing, B, Fafone, V, Fair, H, Fairhurst, S, Fan, X, Farah, A, Farinon, S, Farr, B, Farr, W, Farrow, N, Fauchon-Jones, E, Favata, M, Fays, M, Fazio, M, Feicht, J, Fejer, M, Feng, F, Fenyvesi, E, Ferguson, D, Fernandez-Galiana, A, Ferrante, I, Ferreira, T, Fidecaro, F, Figura, P, Fiori, I, Fishbach, M, Fisher, R, Fittipaldi, R, Fiumara, V, Flaminio, R, Floden, E, Flynn, E, Fong, H, Font, J, Fornal, B, Forsyth, P, Franke, A, Frasca, S, Frasconi, F, Frederick, C, Frei, Z, Freise, A, Frey, R, Fritschel, P, Frolov, V, Fronze, G, Fujii, Y, Fujikawa, Y, Fukunaga, M, Fukushima, M, Fulda, P, Fyffe, M, Gabbard, H, Gadre, B, Gaebel, S, Gair, J, Gais, J, Galaudage, S, Gamba, R, Ganapathy, D, Ganguly, A, Gao, D, Gaonkar, S, Garaventa, B, Garcia-Nunez, C, Garcia-Quiros, C, Garufi, F, Gateley, B, Gaudio, S, Gayathri, V, Ge, G, Gemme, G, Gennai, A, George, J, Gergely, L, Gewecke, P, Ghonge, S, Ghosh, A, Ghosh, S, Giacomazzo, B, Giacoppo, L, Giaime, J, Giardina, K, Gibson, D, Gier, C, Giesler, M, Giri, P, Gissi, F, Glanzer, J, Gleckl, A, Godwin, P, Goetz, E, Goetz, R, Gohlke, N, Goncharov, B, Gonzalez, G, Gopakumar, A, Gosselin, M, Gouaty, R, Grace, B, Grado, A, Granata, M, Granata, V, Grant, A, Gras, S, Grassia, P, Gray, C, Gray, R, Greco, G, Green, A, Green, R, Gretarsson, A, Gretarsson, E, Griffith, D, Griffiths, W, Griggs, H, Grignani, G, Grimaldi, A, Grimes, E, Grimm, S, Grote, H, Grunewald, S, Gruning, P, Guerrero, J, Guidi, G, Guimaraes, A, Guixe, G, Gulati, H, Guo, H, Guo, Y, Gupta, A, Gupta, P, Gustafson, E, Gustafson, R, Guzman, F, Ha, S, Haegel, L, Hagiwara, A, Haino, S, Halim, O, Hall, E, Hamilton, E, Hammond, G, Han, W, Haney, M, Hanks, J, Hanna, C, Hannam, M, Hannuksela, O, Hansen, H, Hansen, T, Hanson, J, Harder, T, Hardwick, T, Haris, K, Harms, J, Harry, G, Harry, I, Hartwig, D, Hasegawa, K, Haskell, B, Hasskew, R, Haster, C, Hattori, K, Haughian, K, Hayakawa, H, Hayama, K, Hayes, F, Healy, J, Heidmann, A, Heintze, M, Heinze, J, Heinzel, J, Heitmann, H, Hellman, F, Hello, P, Helmling-Cornell, A, Hemming, G, Hendry, M, Heng, I, Hennes, E, Hennig, J, Hennig, M, Vivanco, F, Heurs, M, Hild, S, Hill, P, Himemoto, Y, Hines, A, Hiranuma, Y, Hirata, N, Hirose, E, Hochheim, S, Hofman, D, Hohmann, J, Holgado, A, Holland, N, Hollows, I, Holmes, Z, Holt, K, Holz, D, Hong, Z, Hopkins, P, Hough, J, Howell, E, Hoy, C, Hoyland, D, Hreibi, A, Hsieh, B, Hsu, Y, Huang, G, Huang, H, Huang, P, Huang, Y, Hubner, M, Huddart, A, Huerta, E, Hughey, B, Hui, D, Hui, V, Husa, S, Huttner, S, Huxford, R, Huynh-Dinh, T, Ide, S, Idzkowski, B, Iess, A, Ikenoue, B, Imam, S, Inayoshi, K, Inchauspe, H, Ingram, C, Inoue, Y, Intini, G, Ioka, K, Isi, M, Isleif, K, Ito, K, Itoh, Y, Iyer, B, Izumi, K, Jaberianhamedan, V, Jacqmin, T, Jadhav, S, James, A, Jan, A, Jani, K, Janssens, K, Janthalur, N, Jaranowski, P, Jariwala, D, Jaume, R, Jenkins, A, Jeon, C, Jeunon, M, Jia, W, Jiang, J, Jin, H, Johns, G, Jones, A, Jones, D, Jones, J, Jones, P, Jones, R, Jonker, R, Ju, L, Jung, K, Jung, P, Junker, J, Kaihotsu, K, Kajita, T, Kakizaki, M, Kalaghatgi, C, Kalogera, V, Kamai, B, Kamiizumi, M, Kanda, N, Kandhasamy, S, Kang, G, Kanner, J, Kao, Y, Kapadia, S, Kapasi, D, Karat, S, Karathanasis, C, Karki, S, Kashyap, R, Kasprzack, M, Kastaun, W, Katsanevas, S, Katsavounidis, E, Katzman, W, Kaur, T, Kawabe, K, Kawaguchi, K, Kawai, N, Kawasaki, T, Kefelian, F, Keitel, D, Key, J, Khadka, S, Khalili, F, Khan, I, Khan, S, Khazanov, E, Khetan, N, Khursheed, M, Kijbunchoo, N, Kim, C, Kim, J, Kim, K, Kim, W, Kim, Y, Kimball, C, Kimura, N, King, P, Kinley-Hanlon, M, Kirchhoff, R, Kissel, J, Kita, N, Kitazawa, H, Kleybolte, L, Klimenko, S, Knee, A, Knowles, T, Knyazev, E, Koch, P, Koekoek, G, Kojima, Y, Kokeyama, K, Koley, S, Kolitsidou, P, Kolstein, M, Komori, K, Kondrashov, V, Kong, A, Kontos, A, Koper, N, Korobko, M, Kotake, K, Kovalam, M, Kozak, D, Kozakai, C, Kozu, R, Kringel, V, Krishnendu, N, Krolak, A, Kuehn, G, Kuei, F, Kumar, A, Kumar, P, Kumar, R, Kume, J, Kuns, K, Kuo, C, Kuo, H, Kuromiya, Y, Kuroyanagi, S, Kusayanagi, K, Kwak, K, Kwang, S, Laghi, D, Lalande, E, Lam, T, Lamberts, A, Landry, M, Lane, B, Lang, R, Lange, J, Lantz, B, La Rosa, I, Lartaux-Vollard, A, Lasky, P, Laxen, M, Lazzarini, A, Lazzaro, C, Leaci, P, Leavey, S, Lecoeuche, Y, Lee, H, Lee, J, Lee, K, Lee, R, Lehmann, J, Lemaitre, A, Leon, E, Leonardi, M, Leroy, N, Letendre, N, Levin, Y, Leviton, J, Li, A, Li, B, Li, J, Li, K, Li, T, Li, X, Lin, C, Lin, F, Lin, H, Lin, L, Linde, F, Linker, S, Linley, J, Littenberg, T, Liu, G, Liu, J, Liu, K, Liu, X, Llorens-Monteagudo, M, Lo, R, Lockwood, A, Lollie, M, London, L, Longo, A, Lopez, D, Lorenzini, M, Loriette, V, Lormand, M, Losurdo, G, Lough, J, Lousto, C, Lovelace, G, Luck, H, Lumaca, D, Lundgren, A, Luo, L, Macas, R, Macinnis, M, Macleod, D, Macmillan, I, Macquet, A, Hernandez, I, Magana-Sandoval, F, Magazzu, C, Magee, R, Maggiore, R, Majorana, E, Makarem, C, Maksimovic, I, Maliakal, S, Malik, A, Man, N, Mandic, V, Mangano, V, Mango, J, Mansell, G, Manske, M, Mantovani, M, Mapelli, M, Marchesoni, F, Marchio, M, Marion, F, Mark, Z, Marka, S, Marka, Z, Markakis, C, Markosyan, A, Markowitz, A, Maros, E, Marquina, A, Marsat, S, Martelli, F, Martin, I, Martin, R, Martinez, M, Martinez, V, Martinovic, K, Martynov, D, Marx, E, Masalehdan, H, Mason, K, Massera, E, Masserot, A, Massinger, T, Masso-Reid, M, Mastrogiovanni, S, Matas, A, Mateu-Lucena, M, Matichard, F, Matiushechkina, M, Mavalvala, N, Mccann, J, Mccarthy, R, Mcclelland, D, Mcclincy, P, Mccormick, S, Mcculler, L, Mcghee, G, Mcguire, S, Mcisaac, C, Mciver, J, Mcmanus, D, Mcrae, T, Mcwilliams, S, Meacher, D, Mehmet, M, Mehta, A, Melatos, A, Melchor, D, Mendell, G, Menendez-Vazquez, A, Menoni, C, Mercer, R, Mereni, L, Merfeld, K, Merilh, E, Merritt, J, Merzougui, M, Meshkov, S, Messenger, C, Messick, C, Meyers, P, Meylahn, F, Mhaske, A, Miani, A, Miao, H, Michaloliakos, I, Michel, C, Michimura, Y, Middleton, H, Milano, L, Miller, A, Millhouse, M, Mills, J, Milotti, E, Milovich-Goff, M, Minazzoli, O, Minenkov, Y, Mio, N, Mir, L, Mishkin, A, Mishra, C, Mishra, T, Mistry, T, Mitra, S, Mitrofanov, V, Mitselmakher, G, Mittleman, R, Miyakawa, O, Miyamoto, A, Miyazaki, Y, Miyo, K, Miyoki, S, Mo, G, Mogushi, K, Mohapatra, S, Mohite, S, Molina, I, Molina-Ruiz, M, Mondin, M, Montani, M, Moore, C, Moraru, D, Morawski, F, More, A, Moreno, C, Moreno, G, Mori, Y, Morisaki, S, Moriwaki, Y, Mours, B, Mow-Lowry, C, Mozzon, S, Muciaccia, F, Mukherjee, A, Mukherjee, D, Mukherjee, S, Mukund, N, Mullavey, A, Munch, J, Muniz, E, Murray, P, Musenich, R, Nadji, S, Nagano, K, Nagano, S, Nakamura, K, Nakano, H, Nakano, M, Nakashima, R, Nakayama, Y, Nardecchia, I, Narikawa, T, Naticchioni, L, Nayak, B, Nayak, R, Negishi, R, Neil, B, Neilson, J, Nelemans, G, Nelson, T, Nery, M, Neunzert, A, Ng, K, Ng, S, Nguyen, C, Nguyen, P, Nguyen, T, Quynh, L, Ni, W, Nichols, S, Nishizawa, A, Nissanke, S, Nocera, F, Noh, M, Norman, M, North, C, Nozaki, S, Nuttall, L, Oberling, J, O'Brien, B, Obuchi, Y, O'Dell, J, Ogaki, W, Oganesyan, G, Oh, J, Oh, K, Oh, S, Ohashi, M, Ohishi, N, Ohkawa, M, Ohme, F, Ohta, H, Okada, M, Okutani, Y, Okutomi, K, Olivetto, C, Oohara, K, Ooi, C, Oram, R, O'Reilly, B, Ormiston, R, Ormsby, N, Ortega, L, O'Shaughnessy, R, O'Shea, E, Oshino, S, Ossokine, S, Osthelder, C, Otabe, S, Ottaway, D, Overmier, H, Pace, A, Pagano, G, Page, M, Pagliaroli, G, Pai, A, Pai, S, Palamos, J, Palashov, O, Palomba, C, Pan, K, Panda, P, Pang, H, Pang, P, Pankow, C, Pannarale, F, Pant, B, Paoletti, F, Paoli, A, Paolone, A, Parisi, A, Park, J, Parker, W, Pascucci, D, Pasqualetti, A, Passaquieti, R, Passuello, D, Patel, M, Patricelli, B, Payne, E, Pechsiri, T, Pedraza, M, Pegoraro, M, Pele, A, Arellano, F, Penn, S, Perego, A, Pereira, A, Pereira, T, Perez, C, Perigois, C, Perreca, A, Perries, S, Petermann, J, Petterson, D, Pfeiffer, H, Pham, K, Phukon, K, Piccinni, O, Pichot, M, Piendibene, M, Piergiovanni, F, Pierini, L, Pierro, V, Pillant, G, Pilo, F, Pinard, L, Pinto, I, Piotrzkowski, B, Piotrzkowski, K, Pirello, M, Pitkin, M, Placidi, E, Plastino, W, Pluchar, C, Poggiani, R, Polini, E, Pong, D, Ponrathnam, S, Popolizio, P, Porter, E, Powell, J, Pracchia, M, Pradier, T, Prajapati, A, Prasai, K, Prasanna, R, Pratten, G, Prestegard, T, Principe, M, Prodi, G, Prokhorov, L, Prosposito, P, Prudenzi, L, Puecher, A, Punturo, M, Puosi, F, Puppo, P, Purrer, M, Qi, H, Quetschke, V, Quinonez, P, Quitzow-James, R, Raab, F, Raaijmakers, G, Radkins, H, Radulesco, N, Raffai, P, Rail, S, Raja, S, Rajan, C, Ramirez, K, Ramirez, T, Ramos-Buades, A, Rana, J, Rapagnani, P, Rapol, U, Ratto, B, Raymond, V, Raza, N, Razzano, M, Read, J, Rees, L, Regimbau, T, Rei, L, Reid, S, Reitze, D, Relton, P, Renzini, A, Rettegno, P, Ricci, F, Richardson, C, Richardson, J, Richardson, L, Ricker, P, Riemenschneider, G, Riles, K, Rizzo, M, Robertson, N, Robie, R, Robinet, F, Rocchi, A, Rocha, J, Rodriguez, S, Rodriguez-Soto, R, Rolland, L, Rollins, J, Roma, V, Romanelli, M, Romano, J, Romano, R, Romel, C, Romero, A, Romero-Shaw, I, Romie, J, Rose, C, Rosinska, D, Rosofsky, S, Ross, M, Rowan, S, Rowlinson, S, Roy, S, Rozza, D, Ruggi, P, Ryan, K, Sachdev, S, Sadecki, T, Sadiq, J, Sago, N, Saito, S, Saito, Y, Sakai, K, Sakai, Y, Sakellariadou, M, Sakuno, Y, Salafia, O, Salconi, L, Saleem, M, Salemi, F, Samajdar, A, Sanchez, E, Sanchez, J, Sanchez, L, Sanchis-Gual, N, Sanders, J, Sanuy, A, Saravanan, T, Sarin, N, Sassolas, B, Satari, H, Sato, S, Sato, T, Sauter, O, Savage, R, Savant, V, Sawada, T, Sawant, D, Sawant, H, Sayah, S, Schaetzl, D, Scheel, M, Scheuer, J, Schindler-Tyka, A, Schmidt, P, Schnabel, R, Schneewind, M, Schofield, R, Schonbeck, A, Schulte, B, Schutz, B, Schwartz, E, Scott, J, Scott, S, Seglar-Arroyo, M, Seidel, E, Sekiguchi, T, Sekiguchi, Y, Sellers, D, Sergeev, A, Sengupta, A, Sennett, N, Sentenac, D, Seo, E, Sequino, V, Setyawati, Y, Shaffer, T, Shahriar, M, Shams, B, Shao, L, Sharifi, S, Sharma, A, Sharma, P, Shawhan, P, Shcheblanov, N, Shen, H, Shibagaki, S, Shikauchi, M, Shimizu, R, Shimoda, T, Shimode, K, Shink, R, Shinkai, H, Shishido, T, Shoda, A, Shoemaker, D, Shukla, K, Shyamsundar, S, Sieniawska, M, Sigg, D, Singer, L, Singh, D, Singh, N, Singha, A, Sintes, A, Sipala, V, Skliris, V, Slagmolen, B, Slaven-Blair, T, Smetana, J, Smith, J, Smith, R, Somala, S, Somiya, K, Son, E, Soni, K, Soni, S, Sorazu, B, Sordini, V, Sorrentino, F, Sorrentino, N, Sotani, H, Soulard, R, Souradeep, T, Sowell, E, Spagnuolo, V, Spencer, A, Spera, M, Srivastava, A, Srivastava, V, Staats, K, Stachie, C, Steer, D, Steinlechner, J, Steinlechner, S, Stops, D, Stover, M, Strain, K, Strang, L, Stratta, G, Strunk, A, Sturani, R, Stuver, A, Sudbeck, J, Sudhagar, S, Sudhir, V, Sugimoto, R, Suh, H, Summerscales, T, Sun, H, Sun, L, Sunil, S, Sur, A, Suresh, J, Sutton, P, Suzuki, T, Swinkels, B, Szczepanczyk, M, Szewczyk, P, Tacca, M, Tagoshi, H, Tait, S, Takahashi, H, Takahashi, R, Takamori, A, Takano, S, Takeda, H, Takeda, M, Talbot, C, Tanaka, H, Tanaka, K, Tanaka, T, Tanasijczuk, A, Tanioka, S, Tanner, D, Tao, D, Tapia, A, Martin, E, Mertin, E, Tasson, J, Telada, S, Tenorio, R, Terkowski, L, Test, M, Thirugnanasambandam, M, Thomas, M, Thomas, P, Thompson, J, Thondapu, S, Thorne, K, Thrane, E, Tiwari, S, Tiwari, V, Toland, K, Tolley, A, Tomaru, T, Tomigami, Y, Tomura, T, Tonelli, M, Torres-Forne, A, Torrie, C, E Melo, I, Toyra, D, Trapananti, A, Travasso, F, Traylor, G, Tringali, M, Tripathee, A, Troiano, L, Trovato, A, Trozzo, L, Trudeau, R, Tsai, D, Tsang, K, Tsang, T, Tsao, J, Tse, M, Tso, R, Tsubono, K, Tsuchida, S, Tsukada, L, Tsuna, D, Tsutsui, T, Tsuzuki, T, Turconi, M, Tuyenbayev, D, Ubhi, A, Uchikata, N, Uchiyama, T, Udall, R, Ueda, A, Uehara, T, Ueno, K, Ueshima, G, Ugolini, D, Unnikrishnan, C, Uraguchi, F, Urban, A, Ushiba, T, Usman, S, Utina, A, Vahlbruch, H, Vajente, G, Vajpeyi, A, Valdes, G, Valentini, M, Valsan, V, Van Bakel, N, Van Beuzekom, M, Van Den Brand, J, Van Den Broeck, C, Vander-Hyde, D, Van Der Schaaf, L, Van Heijningen, J, Vanosky, J, Van Putten, M, Van Remortel, N, Vardaro, M, Vargas, A, Varma, V, Vasuth, M, Vecchio, A, Vedovato, G, Veitch, J, Veitch, P, Venkateswara, K, Venneberg, J, Venugopalan, G, Verkindt, D, Verma, Y, Veske, D, Vetrano, F, Vicere, A, Viets, A, Villa-Ortega, V, Vinet, J, Vitale, S, Vo, T, Vocca, H, Von Reis, E, Von Wrangel, J, Vorvick, C, Vyatchanin, S, Wade, L, Wade, M, Wagner, K, Walet, R, Walker, M, Wallace, G, Wallace, L, Walsh, S, Wang, J, Wang, W, Ward, R, Warner, J, Was, M, Washimi, T, Washington, N, Watchi, J, Weaver, B, Wei, L, Weinert, M, Weinstein, A, Weiss, R, Weller, C, Wellmann, F, Wen, L, Wessels, P, Westhouse, J, Wette, K, Whelan, J, White, D, Whiting, B, Whittle, C, Wilken, D, Williams, D, Williams, M, Williamson, A, Willis, J, Willke, B, Wilson, D, Winkler, W, Wipf, C, Wlodarczyk, T, Woan, G, Woehler, J, Wofford, J, Wong, I, Wu, C, Wu, D, Wu, H, Wu, S, Wysocki, D, Xiao, L, Xu, W, Yamada, T, Yamamoto, H, Yamamoto, K, Yamamoto, T, Yamashita, K, Yamazaki, R, Yang, F, Yang, L, Yang, Y, Yang, Z, Yap, M, Yeeles, D, Yelikar, A, Ying, M, Yokogawa, K, Yokoyama, J, Yokozawa, T, Yoon, A, Yoshioka, T, Yu, H, Yuzurihara, H, Zadrozny, A, Zanolin, M, Zeidler, S, Zelenova, T, Zendri, J, Zevin, M, Zhan, M, Zhang, H, Zhang, J, Zhang, L, Zhang, R, Zhang, T, Zhao, C, Zhao, G, Zhao, Y, Zhou, Z, Zhu, X, Zhu, Z, Zimmerman, A, Zucker, M, Zweizig, J, RS: FSE Grav. waves and fundamental physics, Grav. waves and fundamental physics, RS: FSE MSP, UCL - SST/IRMP - Institut de recherche en mathématique et physique, Arai, K., Arene, M., Becsy, B., Bustillo, J. C., Diaz, J. C., Cavaglia, M., Cerda-Duran, P., Chiang, C. -Y., Chu, Y. -K., Cieslar, M., Cordero-Carrion, I., Curylo, M., Canton, T. D., Dalya, G., D'Angelo, B., D'Antonio, S., Deleglise, S., D'Emilio, V., Diaz, M. C., D'Onofrio, L., D'Urso, D., Estelles, H., Fronze, G. G., Garcia-Nunez, C., Garcia-Quiros, C., Ghosh, A., Ghosh, S., Gonzalez, G., Guixe, G., Gupta, A., Vivanco, F. H., Hsieh, B. -H., Huang, G. -Z., Huang, H. -Y., Huang, Y. -C., Hubner, M. T., Kefelian, F., Krolak, A., Kumar, R., Kuo, H. -S., Lemaitre, A., Lin, C. -Y., Lin, F. -K., Lin, F. -L., Luck, H., Hernandez, I. M., Magana-Sandoval, F., Magazzu, C., Marka, S., Marka, Z., Mir, L. M., Mo, G., Mukherjee, A., Mukherjee, S., Muniz, E. A., Quynh, L. N., O'Brien, B. D., O'Dell, J., O'Reilly, B., O'Shaughnessy, R., O'Shea, E., Arellano, F. E. P., Perigois, C., Perries, S., Purrer, M., Rosinska, D., Roy, S., Schonbeck, A., Sudbeck, J., Suzuki, T., Szczepanczyk, M. J., Tanaka, K., Tanaka, T., Martin, E. N. T. S., Mertin, E. N. T. S., Tiwari, S., Torres-Forne, A., E Melo, I. T., Toyra, D., Tsao, J. -S., Van Bakel, N., Van Beuzekom, M., Van Den Brand, J. F. J., Van Der Schaaf, L., Van Heijningen, J. V., Van Putten, M. H. P. M., Van Remortel, N., Vasuth, M., Vicere, A., Von Reis, E. R. G., Von Wrangel, J., Wessels, P., Xu, W. -R., Yamamoto, K., Yang, Y., Yu, H., Zadrozny, A., Zhao, Y., LIGO Sci Collaboration, Virgo Collaboration, KAGRA Collaboration, Van Swinderen Institute for Particle Physics and G, and (Astro)-Particles Physics
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gravitational radiation: anisotropy ,Physics and Astronomy (miscellaneous) ,gravitational radiation: stochastic ,Astronomy ,Astrophysics ,01 natural sciences ,General Relativity and Quantum Cosmology ,Physics, Particles & Fields ,Cosmology & Astrophysics ,energy: flux ,energy: density ,gravitational radiation: energy ,LIGO ,QC ,QB ,Physics ,Settore FIS/01 ,Spectral index ,Galactic Center ,Amplitude ,General relativity ,Sidereal time ,Physical Sciences ,[PHYS.GRQC]Physics [physics]/General Relativity and Quantum Cosmology [gr-qc] ,gravitational radiation: power spectrum ,Gravitation ,data analysis method ,Anisotropic stochastic gravitational-wave background ,Experimental studies of gravity ,FOS: Physical sciences ,O3 ,O2 ,General Relativity and Quantum Cosmology (gr-qc) ,Astronomy & Astrophysics ,Stochastic Background, Gravitational Waves, LIGO, Virgo, O1, O2, O3 ,O1 ,Gravitational waves ,UPPER LIMITS ,statistical analysis ,0103 physical sciences ,advanced LIGO and Virgo ,ddc:530 ,KAGRA ,010306 general physics ,STFC ,gravitational waves ,Virgo ,Gravitational Waves ,Science & Technology ,010308 nuclear & particles physics ,Gravitational wave ,gravitational radiation: background ,RCUK ,Galaxy ,VIRGO ,gravitational radiation: emission ,spectrum: density ,RADIATION ,CROSS-CORRELATION SEARCH ,Stochastic Background ,Dewey Decimal Classification::500 | Naturwissenschaften::530 | Physik ,galaxy - Abstract
We report results from searches for anisotropic stochastic gravitational-wave backgrounds using data from the first three observing runs of the Advanced LIGO and Advanced Virgo detectors. For the first time, we include Virgo data in our analysis and run our search with a new efficient pipeline called {\tt PyStoch} on data folded over one sidereal day. We use gravitational-wave radiometry (broadband and narrow band) to produce sky maps of stochastic gravitational-wave backgrounds and to search for gravitational waves from point sources. A spherical harmonic decomposition method is employed to look for gravitational-wave emission from spatially-extended sources. Neither technique found evidence of gravitational-wave signals. Hence we derive 95\% confidence-level upper limit sky maps on the gravitational-wave energy flux from broadband point sources, ranging from $F_{\alpha, \Theta} < {\rm (0.013 - 7.6)} \times 10^{-8} {\rm erg \, cm^{-2} \, s^{-1} \, Hz^{-1}},$ and on the (normalized) gravitational-wave energy density spectrum from extended sources, ranging from $\Omega_{\alpha, \Theta} < {\rm (0.57 - 9.3)} \times 10^{-9} \, {\rm sr^{-1}}$, depending on direction ($\Theta$) and spectral index ($\alpha$). These limits improve upon previous limits by factors of $2.9 - 3.5$. We also set 95\% confidence level upper limits on the frequency-dependent strain amplitudes of quasimonochromatic gravitational waves coming from three interesting targets, Scorpius X-1, SN 1987A and the Galactic Center, with best upper limits range from $h_0 < {\rm (1.7-2.1)} \times 10^{-25},$ a factor of $\geq 2.0$ improvement compared to previous stochastic radiometer searches., Comment: 23 Pages, 9 Figures
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- 2021
91. Vibration isolation systems for the beam splitter and signal recycling mirrors of the KAGRA gravitational wave detector
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Hirotaka Takahashi, T. Sekiguchi, Nami Uchikata, Zong-Hong Zhu, Mitsuhiro Fukushima, H. Y. Huang, Ping Huang, Kimio Tsubono, M. Kamiizumi, R. Kozu, Shuji Saito, K. L. Li, Y. Moriwaki, Y. Mori, Atsushi Nishizawa, Souichi Telada, A. Miyamoto, T. Sawada, Kazuhiro Hayama, D. C. Y. Hui, W. S. Kim, Hiroyuki Nakano, S. Imam, Shigeo Nagano, H. L. Lin, S. Otabe, Takuya Tsutsui, Kei Kotake, Masashi Ohkawa, Jinsook Kim, K. Ito, Soichiro Morisaki, Takashi Sato, Yasufumi Kojima, C. Jeon, M. Marchio, Toshihiro Tsuzuki, T. Yamamoto, Yoichi Aso, Kohei Inayoshi, Nobuyuki Kanda, Hideaki Hayakawa, M. Takeda, Y. Tomigami, Hajime Sotani, Nobutada Kimura, Chunglee Kim, Yuka Fujii, Toshio Suzuki, M. Zhan, F. E. Peña Arellano, Fumihiro Uraguchi, T. Yokozawa, H. K. Tanaka, Hyun Lee, Eiichi Hirose, Kouji Nakamura, K. Yamashita, H. Vocca, Takahiro Tanaka, Satoshi Tsuchida, C. C. Kuo, D. Tuyenbayev, T. Yamada, Sadakazu Haino, H. Pang, C. Wu, K. Ueno, B. Ikenoue, F-L. Lin, Lijing Shao, T. Shimoda, Y. Okutani, K. Kaihotsu, Zhoujian Cao, Yoshiaki Himemoto, I. M. Pinto, S. Tanioka, K. Jung, Y. Sakuno, M. A. Barton, K. Izumi, Albert K. H. Kong, H-S. Kuo, M. Nakano, Wen-Biao Han, G. Ueshima, Y. Huang, Kyujin Kwak, K. Yamamoto, B. H. Hsieh, M. Leonardi, Y. Bae, Yuki Inoue, T. Ushiba, Yuichiro Sekiguchi, K. Shimode, J-S. Tsao, Shuen De Wu, S. Shibagaki, W. Ogaki, Simon Zeidler, Luca Baiotti, Yousuke Itoh, Z. Hong, Yuhang Zhao, E. Capocasa, Kyohei Kawaguchi, Hong Wu, Y. Kuromiya, L. Nguyen Quynh, Hiroyuki Takeda, Haruki Kitazawa, Y. Hiranuma, T. Narikawa, R. Bajpai, J. Park, Ryo Yamazaki, Y. M. Kim, H. Chu, A. Hagiwara, Hisa-aki Shinkai, C-Y. Lin, S. Sato, N. Hirata, Jun'ichi Yokoyama, Keiko Kokeyama, L. Naticchioni, T. Shishido, C-Y. Chiang, Yi Chen, R. Sugimoto, Y. Nakayama, Takashi Uchiyama, Kunihito Ioka, Yutaro Enomoto, K. Hattori, R. Nakashima, L. Trozzo, K. Oh, Yoshiyuki Obuchi, E. N. Tapia San Martin, Y. Sakai, K. Sakai, D. Gao, T. Yoshioka, N. Kawai, Norichika Sago, Akiteru Takamori, Kazuyuki Tanaka, S. Eguchi, F. K. Lin, R. Flaminio, H. B. Jin, T. Kawasaki, Akito Araya, Shinji Miyoki, G. Kang, H. Ohta, S. Takano, Kentaro Somiya, R. Hatoya, T. Kajita, A. Parisi, T. Washimi, S. Bae, A. Shoda, S. Oshino, S. Ide, H. Zhang, Masaki Ando, K. Hasegawa, E. J. Son, J. Kume, M. H. P. M. van Putten, Jishnu Suresh, Yi Yang, Yoshio Arai, C. Chen, A. Ueda, T. Tomura, K. Miyo, K. Oohara, Sakae Araki, Osamu Miyakawa, K. Okutomi, Sachiko Kuroyanagi, Tomotada Akutsu, Hideki Asada, R. Shimizu, L. C.-C. Lin, Naoki Aritomi, N. Kita, T. Tsang, Ryutaro Takahashi, Kuo-Chuan Pan, M. Chan, R. Negishi, Seog Oh, Takayuki Tomaru, Jung-Hoon Kim, Ettore Majorana, P. Jung, M. Fukunaga, G-Z. Huang, Yoshihiko Saito, Kunihiro Nagano, John J. Oh, G. Ge, C. Kozakai, Y. Fujikawa, Wei-Tou Ni, Kentaro Komori, Hideyuki Tagoshi, S. Nozaki, Norikatsu Mio, Kai-Feng Chen, S. Ha, T. Uehara, H. Yuzurihara, Masako Kakizaki, Kipp Cannon, L. W. Luo, Yuta Michimura, Rajesh Kumar, K. Kusayanagi, Ray-Kuang Lee, Hyang Woon Lee, Y. Miyazaki, Guo-Chin Liu, J. Z. Wang, Y-K. Chu, K. Yokogawa, Koji Arai, Masatake Ohashi, Naoko Ohishi, W-R. Xu, C. P. Ooi, F. Travasso, Laboratoire d'Annecy de Physique des Particules (LAPP), and Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-Centre National de la Recherche Scientifique (CNRS)
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Gravitational-wave observatory ,Physics and Astronomy (miscellaneous) ,7. Clean energy ,01 natural sciences ,Signal ,law.invention ,gravitational wave detectors ,Optics ,law ,gravitational waves, vibration isolation, underground experiments, gravitational wave detectors ,0103 physical sciences ,KAGRA ,Interferometric gravitational wave detector ,[PHYS.PHYS.PHYS-INS-DET]Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det] ,010306 general physics ,mirror ,Physics ,010308 nuclear & particles physics ,Payload ,business.industry ,Detector ,oscillation ,optics ,vibration isolation ,Vibration isolation ,underground experiments ,gravitational waves ,mechanical engineering ,gravitational radiation detector: interferometer ,business ,Beam splitter ,mechanics ,performance - Abstract
KAGRA is an underground interferometric gravitational wave detector which is currently being commissioned. This detector relies on high-performance vibration-isolation systems to suspend its key optical components. These suspensions come in four different configurations, of which the type-B is used for the beam splitter and signal recycling mirrors. The type-B suspension comprises the payload, three geometric anti-spring filters for vertical isolation and one inverted pendulum for horizontal isolation. The payload comprises the optic, its marionette and their recoil masses, which hold local displacement sensors and coil magnet actuators used for damping the resonant modes of oscillation of the suspension itself. The beam splitter version has a modified lower section to accommodate a wider optical component. The payload is also equipped with an optical lever, used to monitor and control the position of the suspended optics from the ground. All four suspensions have now been installed in vacuum chambers. We describe the mechanical, electrical and control design, and the measured performance compared to requirements.
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- 2021
92. Prevention of dental caries by eating vegetables at the beginning of a meal in Japanese children
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K, Ito, A, Isumi, S, Doi, M, Ochi, T, Fujiwara, K, Ito, A, Isumi, S, Doi, M, Ochi, and T, Fujiwara
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16th World Congress on Public Health 2020;2020.10.12-16;Web(Rome), source:European Journal of Public Health. 2020;30(Supplement_5):ckaa166.384., source:https://doi.org/10.1093/eurpub/ckaa166.384
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- 2021
93. POS1339 FACTORS RELATED TO SERUM IgG4 ELEVATION AND DEVELOPMENT OF IgG4-RELATED DISEASE: DATA FROM RESIDENT EXAMINATION
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S. Tsuge, H. Fujii, M. Tamai, I. Mizushima, M. Yoshida, N. Suzuki, Y. Takahashi, A. Takeji, S. Horita, Y. Fujisawa, T. Matsunaga, T. Zoshima, R. Nishioka, H. Nuka, S. Hara, Y. Tani, Y. Suzuki, K. Ito, K. Yamada, S. Nakazaki, A. Kawakami, and M. Kawano
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Rheumatology ,Immunology ,Immunology and Allergy ,General Biochemistry, Genetics and Molecular Biology - Abstract
BackgroundElevated serum IgG4 levels are one of the characteristic findings in immunoglobulin G4 (IgG4)-related disease (IgG4-RD). Serum IgG4 levels have an impact to a certain extent on the diagnosis of IgG4-RD although there are some issues in their sensitivity and specificity. In the reports from Japan, China, USA, and Europe, elevated serum IgG4 levels were reported to be observed in 83-97% of patients with IgG4-RD [1-5]. In the past investigations of hospital patients, some studies reported that 10-15% of hospital patients with elevated serum IgG4 levels had IgG4-RD [6,7]. However, in general adults with no symptom, investigations of prevalence of elevated serum IgG4 levels and/or IgG4-RD have rarely been conducted.ObjectivesThis study aimed to investigate the frequency of serum IgG4 elevation in the general Japanese population and its associated factors using data from resident examinations.MethodsWe measured the serum IgG4 levels in 1,204 residents who underwent a general medical examination in Ishikawa prefecture, Japan. Logistic regression analysis was used to search for factors related to elevated serum IgG4 levels. Secondary examinations were conducted for participants in whom elevation was identified.ResultsThe mean serum IgG4 level was 44 mg/dL, and elevated serum IgG4 levels were observed in 42 patients (3.5%). Univariate logistic regression analyses showed that male sex, older age, lower estimated glomerular filtration rates based on cystatin C (eGFR-CysC), serum high-density lipoprotein cholesterol levels, and higher hemoglobin A1c (HbA1c) levels were associated with elevated serum IgG4 levels. Subgroup analyses in men showed that older age, lower eGFR-CysC levels, and higher serum HbA1c levels were associated with elevated serum IgG4 levels. In contrast, the analyses in women found no significant factors. One of the 10 residents who underwent secondary examinations was diagnosed with possible IgG4-related retroperitoneal fibrosis.ConclusionIn the general population, elevated serum IgG4 levels are more common in elderly men, which is similar to the epidemiological features of IgG4-RD.References[1]Inoue D, et al. IgG4-related disease: dataset of 235 consecutive patients. Medicine (Baltimore). 2015;94(15):e680.[2]Yamada K, et al. New clues to the nature of immunoglobulin G4-related disease: a retrospective Japanese multicenter study of baseline clinical features of 334 cases. Arthritis Res Ther. 2017;19(1):262[3]Culver EL, et al. Elevated serum IgG4 levels in diagnosis, treatment response, organ involvement, and relapse in a prospective IgG4-related disease UK cohort. Am J Gastroenterol 2016;111:733–43.[4]Lin W, et al. Clinical characteristics of immunoglobulin G4-related disease: a prospective study of 118 Chinese patients. Rheumatology (Oxford). 2015;54(11):1982–90.[5]Carruthers MN, et al. The diagnostic utility of serum IgG4 concentrations in IgG4-related disease. Ann Rheum Dis 2015;74:14-18.[6]James Yun, et al. Poor positive predictive value of serum immunoglobulin G4 concentrations in the diagnosis of immunoglobulin G4-related sclerosing disease. Asia Pac Allergy. 2014 Jul;4(3):172-176.[7]Taiwo N Ngwa, et al. Sreum immunoglobulin G4 level is a poor predictor of immunoglobulin G4–related disease. Pancreas. 2014 Jul;43(5):704-7.Disclosure of InterestsNone declared
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- 2022
94. TARGETED PROTEOMIC ANALYSIS TO EXPLORE THE ANTI-INFLAMMATORY EFFECTS OF NOTOCHORDAL CELL-DERIVED MATRIX
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L.T. Laagland, F.C. Bach, F.M. Riemers, A. Medzikovic, G. Erdmann, L.B. Creemers, C. Sachse, K. Ito, M. Templin, and M.A. Tryfonidou
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Rheumatology ,Biomedical Engineering ,Orthopedics and Sports Medicine - Published
- 2022
95. 354 Bevacizumab with metronomic oral cyclophosphamide for patients with recurrent cervical cancer
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Kayo Inoue, Tomoko Ueda, Hiroshi Tsubamoto, M Goto, K Ito, R Isono, and Y Takimoto
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Cervical cancer ,Chemotherapy ,medicine.medical_specialty ,Bevacizumab ,business.industry ,medicine.medical_treatment ,Standard treatment ,Neutropenia ,medicine.disease ,Gastroenterology ,Regimen ,Internal medicine ,medicine ,Adverse effect ,business ,Progressive disease ,medicine.drug - Abstract
No standard treatment is available for 2nd line, especially for patients who experience anaphylaxis to platinum, or develop early recurrence. Previously, we reported 4 cases treated with 50 mg of oral cyclophosphamide daily and 15 mg/kg of intravenous bevacizumab every 3 weeks (mCPA-BEV). Here, we report follow up of the 4 cases and the additional cases. Methods Patients with cervical cancer who had anaphylaxis to platinum or who recurred less than 6 months after the last administration of cisplatin, and treated with mCPA-BEV were retrospectively reviewed. Adverse events and response rate were recorded according to CTCAE ver 5.0 and RECIST ver 1.1, respectively. Results During 2016 and 2020, 11 patients were enrolled. Histology of the tumor were SCC in 6, adeno in 3, adeno-SCC in 1, and LCNEC in 1. Two patients had platinum anaphylaxis, 7 patients had progressive disease during previous chemotherapy, and 2 patients recurred within 6 months. One patient suffered from grade 3 neutropenia; however, no grade 2 or higher non-hematological toxicities were observed. Median duration of chemotherapy was 4.1M (range 0.2–30.6 M). One patient had CR in RECIST criteria, and none had PR. Median PFS was 4.1 months (95%CI: 2.1–11.3M), and median OS was 33.7M (95%CI: 13.5–33.7M, figure 1). Conclusion The tumor dormancy was probably maintained by long administration with mild toxicities. These cases demonstrate the use of mCPA-BEV with minimal toxicity and expected anti-cancer activity and indicate that this regimen could be considered for the second-line chemotherapy in advanced recurrent cervical cancer.
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- 2020
96. Usefulness of lead delivery catheter system for true right ventricular septal pacing
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Yuichiro Maekawa, F Kin, Tomoyuki Watanabe, K Ito, T. Urushida, Yoshihisa Naruse, Y Takashima, K Miyajima, A Okazaki, Y Kawaguchi, and Yasushi Wakabayashi
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medicine.medical_specialty ,Catheter ,business.industry ,Internal medicine ,Cardiology ,Medicine ,Cardiology and Cardiovascular Medicine ,business ,Lead (electronics) - Abstract
Background Right ventricular (RV) septal pacing is often selected to preserve a more physiologic ventricular activation. But the pacing leads are not always located in true septal wall, rather in hinge or free wall in some cases with the conventional stylet-guided lead implantation. In recent years, new guiding catheter systems has attracted attention as a solution to that problem. Objective The aim of this study is to investigate that true ventricular sepal pacing can be achieved by use of the new guiding catheter system for pacing lead. Methods We enrolled 198 patients who underwent RV septal lead implantation and computed tomography (CT) after pacemaker implantation. 16 cases were used delivery catheter (Delivery), and 182 cases were used stylet for targeting ventricular septum (Conventional). We analyzed the lead locations with CT, and evaluated capture thresholds, R-wave amplitudes, lead impedances and 12-lead electrocardiogram findings one month after implantation. Results All cases of delivery catheter group had true septal lead positions (Delivery; 100% vs Conventional; 44%, p Conclusions The delivery catheter system designated for pacing lead can contribute to select the true ventricular septal sites and to attain the more physiologic ventricular activation. Funding Acknowledgement Type of funding source: None
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- 2020
97. 312 Combination therapy of oral cyclophosphamide and bevacizumab for patients with recurrent ovarian and peritoneal cancer
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R Isono, K Hori, Y Takimoto, M Goto, K Ito, R Tashima, M Yamashita, E Yoshioka, Hiroshi Tsubamoto, and M Onoue
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Chemotherapy ,medicine.medical_specialty ,Bevacizumab ,Combination therapy ,business.industry ,medicine.medical_treatment ,Neutropenia ,medicine.disease ,Gastroenterology ,Regimen ,Quality of life ,Internal medicine ,Medicine ,business ,Ovarian cancer ,Esophagitis ,medicine.drug - Abstract
Objective The purpose of chemotherapy for recurrent cancer is to get survival benefit, relieve symptoms, and improve quality of life. We used oral cyclophosphamide (CPA) and bevacizumab (BEV) combination therapy in cases of recurrent ovarian and peritoneal cancer, where standard chemotherapy was difficult to conduct. We subsequently evaluated the safety and efficacy of this treatment. Methods Between August 2014 and June 2020, subjects who provided informed consent received the following regimen: oral CPA 50 mg daily and intravenous BEV15 mg/kg every 3 weeks as 1 cycle. Data from the two facilities were retrospectively studied. Result Twenty-two patients were enrolled (20 with ovarian cancer and 2 with peritoneal cancer). The median follow-up period was 18.9 months (range, 5.0–51.5), and median age was 60 years (range 37–81). Sixteen patients had platinum resistance. The median number of previous chemotherapy regimens was 2.5 (range 0–5). The median implementation cycle was 5 (range 2–14). Eighteen patients discontinued treatment: three due to side effects, and fifteen due to disease progression. Grade 2 toxicities included neutropenia (1), protein urea (1), hypertension (2), and esophagitis (1). Two patients had a complete response, and one patient had a partial response. Five patients had stable disease. The response rate was 13.6%. Median PFS was 5.3 months (range, 0.8–23.5). The median OS from the initiation of CPA/BEV was 9.2 months (range, 4.8–51.5+). Conclusions The combination therapy of oral cyclophosphamide and bevacizumab had relatively effective, and can be used safely in patients who have become difficult to treat after second-line chemotherapy.
- Published
- 2020
98. Observation of Coulomb-Assisted Nuclear Bound State of Ξ^{-}-^{14}N System
- Author
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S H, Hayakawa, K, Agari, J K, Ahn, T, Akaishi, Y, Akazawa, S, Ashikaga, B, Bassalleck, S, Bleser, H, Ekawa, Y, Endo, Y, Fujikawa, N, Fujioka, M, Fujita, R, Goto, Y, Han, S, Hasegawa, T, Hashimoto, T, Hayakawa, E, Hayata, K, Hicks, E, Hirose, M, Hirose, R, Honda, K, Hoshino, S, Hoshino, K, Hosomi, S H, Hwang, Y, Ichikawa, M, Ichikawa, K, Imai, K, Inaba, Y, Ishikawa, H, Ito, K, Ito, W S, Jung, S, Kanatsuki, H, Kanauchi, A, Kasagi, T, Kawai, M H, Kim, S H, Kim, S, Kinbara, R, Kiuchi, H, Kobayashi, K, Kobayashi, T, Koike, A, Koshikawa, J Y, Lee, T L, Ma, S Y, Matsumoto, M, Minakawa, K, Miwa, A T, Moe, T J, Moon, M, Moritsu, Y, Nagase, Y, Nakada, M, Nakagawa, D, Nakashima, K, Nakazawa, T, Nanamura, M, Naruki, A N L, Nyaw, Y, Ogura, M, Ohashi, K, Oue, S, Ozawa, J, Pochodzalla, S Y, Ryu, H, Sako, S, Sato, Y, Sato, F, Schupp, K, Shirotori, M M, Soe, M K, Soe, J Y, Sohn, H, Sugimura, K N, Suzuki, H, Takahashi, T, Takahashi, T, Takeda, H, Tamura, K, Tanida, A M M, Theint, K T, Tint, Y, Toyama, M, Ukai, E, Umezaki, T, Watabe, K, Watanabe, T O, Yamamoto, S B, Yang, C S, Yoon, J, Yoshida, M, Yoshimoto, D H, Zhang, and Z, Zhang
- Abstract
In an emulsion-counter hybrid experiment performed at J-PARC, a Ξ^{-} absorption event was observed which decayed into twin single-Λ hypernuclei. Kinematic calculations enabled a unique identification of the reaction process as Ξ^{-}+^{14}N→_{Λ}^{10}Be+_{Λ}^{5}He. For the binding energy of the Ξ^{-} hyperon in the Ξ^{-}-^{14}N system a value of 1.27±0.21 MeV was deduced. The energy level of Ξ^{-} is likely a nuclear 1p state which indicates a weak ΞN-ΛΛ coupling.
- Published
- 2020
99. Effects of land use and vegetation on nighttime air temperature in heat vulnerable neighborhoods in New York City
- Author
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K. Charles-Guzman, B. Gunther, K. Ito, L. Smalls-Mantey, and S. Johnson
- Subjects
Hydrology ,Land use ,Air temperature ,medicine ,General Earth and Planetary Sciences ,Environmental science ,medicine.symptom ,Vegetation (pathology) ,General Environmental Science - Published
- 2020
100. Developing a framework to connect health equity energy, and green infrastructure for heat impacts mitigation in New York City
- Author
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K. Ito, B. Gunther, K. Charles-Guzman, L. Smalls-Mantey, and S. Johnson
- Subjects
Energy (esotericism) ,General Earth and Planetary Sciences ,Business ,Environmental economics ,Green infrastructure ,Health equity ,General Environmental Science - Published
- 2020
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