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56. Can Trait Anxiety, Grades, and Test Scores Measured Prior to Medical School Matriculation Predict Clerkship Performance?

Author

Jones, Bonnie J.

Abstract

A study followed 66 medical students from matriculation through clerkship to determine the use of an anxiety measure, undergraduate grades, and Medical College Admission Test scores in predicting clerkship performance. Results showed disparities in prediction but suggest that the way students are evaluated in clerkships determined which factors predicted performance. (MSE)

Published
1991

60. Idiopathic CD4+ T-lymphocytopenia - an analysis of five patients with unexplained opportunistic infections

Author

Spira, Thomas J., Jones, Bonnie M., Nicholson, Janet K.A., Lal, Renu B., Rowe, Thomas, Mawle, Alison C., Lauter, Carl B., Shulman, Jonas A., and Monson, Roberta A.

Subjects
Opportunistic infections -- Case studies, Immunodeficiency -- Case studies, CD4 lymphocytes -- Physiological aspects
Abstract

The immunological activity and the disease progression characteristic of HIV infection are not seen in patients who have CD4+ lymphocytopenia without HIV infection. CD4+ T-lymphocytopenia is the depletion of certain white blood cells and is normally associated with HIV infection. Of five patients with CD4+ T-lymphocytopenia and unexplained opportunistic infections, none were infected with either HIV or human T-cell lymphotropic virus. The patients' spouses and one patient's blood donors were all healthy and had normal levels of CD4+ T-cells. Furthermore, there were no signs in these patients of any other virus-like particles that might be capable of killing CD4+ T-cells. In comparison with 100 HIV-infected patients and 30 healthy individuals, these five patients had lower counts of CD4+ cells. Immunoglobulin levels, which are usually increased in HIV patients, were normal or lower than normal in these five patients. CD4+ T-cell counts continue to drop in patients with HIV, but in these patients, levels of CD4+ T-cells changed little over time.

Published
1993

63. High energy large scale blast sound propagation experiments

Author

Pater, Larry L.; White, Michael J.; Swearingen, Michelle E.; Nykaza, Edward T.; MacAllister, Bruce A.; Mifflin, Jeffery A.; Valente, Daniel P.; Nemeth, Sarah B.; Wilson, D. Keith; Albert, Donald G.; Jones, Bonnie J., United States. Army. Corps of Engineers; Engineer Research and Development Center (U.S.); Construction Engineering Research Laboratory (U.S.); Cold Regions Research and Engineering Laboratory (U.S.); U.S. Army Public Health Command, Pater, Larry L.; White, Michael J.; Swearingen, Michelle E.; Nykaza, Edward T.; MacAllister, Bruce A.; Mifflin, Jeffery A.; Valente, Daniel P.; Nemeth, Sarah B.; Wilson, D. Keith; Albert, Donald G.; Jones, Bonnie J., and United States. Army. Corps of Engineers; Engineer Research and Development Center (U.S.); Construction Engineering Research Laboratory (U.S.); Cold Regions Research and Engineering Laboratory (U.S.); U.S. Army Public Health Command

Abstract

ERDC TR-17-16 High Energy Large Scale Blast Sound Propagation Experiments Engineer Research and Development Center Larry L. Pater, Michael J. White, Donald G. Albert, Michelle E. Swearingen, D. Keith Wilson, Edward T. Nykaza, Bruce A. Macallister, Jeffrey A. Mifflin, Bonnie J. Jones, Daniel P. Valente, and Sarah B. Nemeth March 2017 Approved for public release; distribution is unlimited. The U.S. Army Engineer Research and Development Center (ERDC) solves the nation’s toughest engineering and environmental challenges. ERDC develops innovative solutions in civil and military engineering, geospatial sciences, water resources, and environmental sciences for the Army, the Department of Defense, civilian agencies, and our nation’s public good. Find out more at www.erdc.usace.army.mil. To search for other technical reports published by ERDC, visit the ERDC online library at http://acwc.sdp.sirsi.net/client/default. ERDC TR-17-16 March 2017 High Energy Large Scale Blast Sound Propagation Experiments Larry L. Pater, Michael J. White, Michelle E. Swearingen, Edward T. Nykaza, Bruce A. Macallister, Jeffrey A. Mifflin, Daniel P. Valente, and Sarah B. Nemeth Construction Engineering Research Laboratory (CERL) U.S. Army Engineer Research and Development Center 2902 Newmark Dr. Champaign, IL 61822-1076 D. Keith Wilson, Donald G. Albert, and Bonnie J. Jones Cold Regions Research Laboratory (CRREL) U.S. Army Engineer Research and Development Center 72 Lyme Rd Hanover, NH 03755-1290 Final Report Approved for public release; distribution is unlimited. Prepared for U.S. Army Public Health Command Aberdeen Proving Ground, MD 21012-5403 Under Physics Models Environmental Quality Technology Program, Project 622720D048, Work Unit C43279 ERDC TR-17-16 ii Abstract Atmospheric conditions greatly affect the propagation of the sound. Currently, little information exists regarding the amount of variation in level and spectra of blast noise that is caused by changing meteorological conditions al

Published
2017

68. Helping Teachers Teach the LD Student

Author

Jones, Bonnie

Abstract

This article outlines an inservice program for regular teachers dealing with learning disabled students, with emphasis upon identification of problems and ways of dealing with them. (JD)

Published
1977

71. Brief of Dr. Carhart et al. in Stenberg v. Carhart(*).

Author

HUG, JERRY M., STOLER, ALAN G., HELLER, SIMON, BENSHOFF, JANET, SMITH, PRISCILLA J., JONES, BONNIE SCOTT, ROSENTHAL, LINDA, NOVAK, SUZANNE, and AMIRI, BRIGITTE

Abstract

Questions Presented 1. Whether the Nebraska partial-birth abortion statute violates women's right to privacy because it bans a broad range of abortion procedures, including the safest method of second-trimester abortion, [...]

Published
2000

73. Increased immunogenicity to P815 cells modified with malondialdehyde and acetaldehyde

Author

Willis, Monte S., Jones, Bonnie L., Tuma, Dean J., Duryee, Michael J., Thiele, Geoffrey M., and Klassen, Lynell W.

Subjects
otorhinolaryngologic diseases, hemic and immune systems, chemical and pharmacologic phenomena
Abstract

Aldehyde modified proteins have been associated with the development and/or progression of alcoholic liver disease (ALD). These protein adducts are capable of initiating many immunological responses that are harmful to the normal homeostasis of organism function. Previous studies have shown that malondialdehyde (MDA) and acetaldehyde (AA) synergistically form a unique adduct (MAA) with soluble proteins, which are capable of inducing cytokine release, T-cell proliferation, and antibody production. The purpose of this study was to determine whether MAA-adduction can elicit similar responses to cells using a well-defined tumor model. The mouse mastocytoma P815 tumor cell line was modified with MAA (P815-MAA) or left unmodified (P815) and 106 irradiated cells were injected into DBA/2 mice once a week for 5 weeks. Serum was collected and tested for antibody responses to P815 cells and the MAA epitope. Immunization of MAA-adducted P815 cells into syngeneic DBA/2 mice induced a strong antibody response to the MAA epitope as determined by ELISA on Alb and MAA-Alb (508 µg/ml and 1092 µg/ml, respectively). In addition, antibody to unmodified P815 cells was detected by fluorescent technique. Mice immunized with P815 cells or PBS showed little or no reactivity to the MAA epitope or P815 cells. Studies to assess IL-12 stimulation showed that peritoneal macrophages from P815 and PBS immunized animals produced modest amounts of IL-12 (20 and 35 pg/ml) when stimulated with Alb or MAA-Alb. However, macrophage from P815-MAA immunized mice responded to soluble MAA-adduct (142 pg/ml). Finally, in tumor survival studies the mean survival was 14.25 days in PBS treated mice; 15.75 days with P815 immunized mice and 18.25 days with P815-MAA immunized mice. Therefore, these data strongly suggest that antibody responses are induced by P815 cells modified with MAA-adducts. This may be a possible tool to begin looking at how alcohol metabolites potentially modify cells and/or cellular components making them recognizable to the immune system as foreign. It is thought that these studies define a model system that will be useful in assessing antibody and potentially T cell responses to cells that are modified by MAA.

Published
2008
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80. Maternal Mortality from Obstructed Labor: A MANDATE Analysis of the Ability of Technology to Save Lives in Sub-Saharan Africa.

Author

Harrison, Margo S., Griffin, Jennifer B., McClure, Elizabeth M., Jones, Bonnie, Moran, Katelin, and Goldenberg, Robert L.

Subjects
HEMORRHAGE complications, HEMORRHAGE diagnosis, ANTIBIOTICS, BLOOD transfusion, INFECTION, LABOR complications (Obstetrics), MATHEMATICS, MATERNAL mortality, STATISTICAL models, UTERINE rupture, DISEASE complications, DIAGNOSIS, THERAPEUTICS, PREVENTION
Abstract

Objective The aim of the study is to evaluate clinical interventions to significantly reduce maternal mortality from prolonged labor, obstructed labor, and prolonged obstructed labor (PL/OL/POL) in sub-Saharan Africa (SSA). Methods A mathematical model--Maternal and Neonatal Directed Assessment of Technology ("MANDATE")--was created for SSA with estimated prevalence for PL/OL/POL and case fatality rates from hemorrhage, infection, and uterine rupture. Based on a literature review and expert opinion, the model was populated with estimated likelihoods of the current healthcare system ability to diagnose, transfer, and treat women with these conditions. Impact on maternal mortality of improved diagnosis, transfer, and delivery to relieve PL/OL/POL was assessed. Results Without current technologies, the model estimated 8,464 maternal deaths annually in SSA from these conditions. Imputing current diagnosis, transfer, and treatment of PL/OL/POL, an estimated 7,033 maternal deaths occur annually from these complications. With improved PL/OL/POL diagnosis and improved transfer, 1,700 and 740 lives could be saved, respectively. Improved diagnosis, transfer, and treatment for PL/OL/POL reduce the mortality rate to 864 maternal deaths annually, saving 6,169 lives. If improved transfusion and antibiotic use were added, only 507 women per year would die from PL/OL/POL in SSA. Conclusion In SSA, increasing diagnostics, transfer to higher care, and operative delivery could substantially reduce maternal mortality from PL/OL/POL. Synopsis A computerized model of obstructed labor in SSA was created to explore the interventions necessary to reduce maternal mortality from this condition. [ABSTRACT FROM AUTHOR]

Published
2016
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