51. Ciprofloxacin interacts with thyroid replacement therapy
- Author
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Sofia K Frost, Øyvind Skadberg, John G. Cooper, and Knut Harboe
- Subjects
endocrine system ,Pediatrics ,medicine.medical_specialty ,endocrine system diseases ,Levothyroxine ,Administration, Oral ,Thyroid-stimulating hormone ,Anti-Infective Agents ,Hypothyroidism ,Ciprofloxacin ,medicine ,Humans ,Drug Interactions ,Thyroid cancer ,General Environmental Science ,Antibacterial agent ,Aged ,Aged, 80 and over ,Have Nausea ,business.industry ,Osteomyelitis ,Contraindications ,Thyroid ,General Engineering ,General Medicine ,medicine.disease ,Surgery ,Thyroxine ,medicine.anatomical_structure ,Papers ,Vomiting ,General Earth and Planetary Sciences ,Female ,medicine.symptom ,business ,medicine.drug - Abstract
We report two cases of unexplained hypothyroidism in patients taking oral ciprofloxacin (figure). Nursing staff gave levothyroxine. Prescription charts showed no drug administration errors. Patients did not have nausea, vomiting, or diarrhoea. Unexplained hypothyroidism in patients taking oral ciprofloxacin ### Case 1 An 80 year old woman with advanced thyroid cancer had maintained suppressed concentrations of thyroid stimulating hormone and stable free thyroxine by taking 125 μg levothyroxine daily. She was admitted with a pathological fracture of the femur and complicating osteomyelitis. After four weeks' treatment with oral …
- Published
- 2005