51. Preoperative INR and postoperative major bleeding and mortality: A retrospective cohort study
- Author
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Antoine N. Saliba, Khaled M. Musallam, Ali T. Taher, Muhyeddine Al-Taki, Jamal J. Hoballah, Hani Tamim, Mohamad Habbal, and Sarah Jamali
- Subjects
Adult ,Male ,endocrine system ,medicine.medical_specialty ,Postoperative Hemorrhage ,Logistic regression ,03 medical and health sciences ,0302 clinical medicine ,health services administration ,Preoperative Care ,medicine ,Humans ,heterocyclic compounds ,In patient ,International Normalized Ratio ,cardiovascular diseases ,Aged ,Retrospective Studies ,Aged, 80 and over ,Prothrombin time ,030222 orthopedics ,medicine.diagnostic_test ,business.industry ,fungi ,Retrospective cohort study ,Hematology ,Odds ratio ,Middle Aged ,Acs nsqip ,Surgery ,030220 oncology & carcinogenesis ,Hemostasis ,Female ,Cardiology and Cardiovascular Medicine ,business ,Major bleeding - Abstract
Little research has been done on the current cut-off international normalized ratio (INR) value of 1.5 for patients undergoing surgery. The objectives of this study are to assess the association between INR and postoperative major bleeding and mortality in patients undergoing surgery and to identify an ideal pre-operative INR for surgical patients. We analyzed data from the American College of Surgeons’ National Surgical Quality Improvement Program database between 2008 and 2011 (636,231 patients). The primary outcomes were major bleeding and mortality at 30 days postoperatively. Multivariate logistic regression analyses were carried out to assess these associations. Compared to an INR of
- Published
- 2015
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