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284,651 results on '"Insulin resistance"'

60. Glycemic Effect of Diazoxide in NAFLD

Author

University of California, Berkeley, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), and Joshua Cook, Assistant Professor of Medicine

Published
2024

62. Pancreatic Clamp in NAFLD

Author

Albert Einstein College of Medicine, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), and Joshua Cook, Assistant Professor of Medicine

Published
2024

64. Food insecurity, poor diet, and metabolic measures: The roles of stress and cortisol

Author

Chiu, Dorothy T, Parker, Jordan E, Wiley, Cameron R, Epel, Elissa S, Laraia, Barbara A, Leung, Cindy W, and Tomiyama, A Janet

Subjects
Public Health, Biomedical and Clinical Sciences, Nutrition and Dietetics, Health Sciences, Nutrition, Clinical Research, Behavioral and Social Science, Obesity, Prevention, Mental Health, Health Disparities, 2.1 Biological and endogenous factors, 2.3 Psychological, social and economic factors, Metabolic and endocrine, Oral and gastrointestinal, Zero Hunger, Humans, Female, Hydrocortisone, Food Supply, Diet, Food Insecurity, Glucose, Sugars, Sodium, Stress, Psychological, Food insecurity, Stress, Cortisol, Waist circumference, Insulin resistance, Nutrition & Dietetics
Abstract

Food insecurity is highly prevalent and linked to poorer diet and worse metabolic outcomes. Food insecurity can be stressful, and could elicit chronic psychological and physiological stress. In this study, we tested whether stress could be used to identify those at highest risk for worse diet and metabolic measures from food insecurity. Specifically, we hypothesized that cortisol (a physiological marker of stress) and perceived psychological stress would amplify the link between food insecurity and hyperpalatable food intake as well as metabolic measures. In a sample of 624 Black and White women aged 36-43 who participated in the NHLBI Growth and Health Study's midlife assessment, we assessed associations between food insecurity with hyperpalatable food intake (high fat + high sodium foods; high fat + high sugar foods; and high carbohydrate + high sodium foods), and metabolic measures (fasting glucose, insulin resistance, and waist circumference). We found that food insecurity was associated with higher levels of perceived stress (R2 = 0.09), and greater intake of high fat + high sugar (hyperpalatable) foods (R2 = 0.03). In those with higher cumulative cortisol (as indexed by hair cortisol), food insecurity was associated with higher levels of fasting glucose. Neither cortisol nor perceived stress moderated any other relationships, and neither variable functioned as a mediator in sensitivity analyses. Given these largely null findings, further research is needed to understand the role stress plays in the chronic health burdens of food insecurity.

Published
2024

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